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2-aminopurine and guanosine

2-aminopurine has been researched along with guanosine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (42.86)18.2507
2000's4 (28.57)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlson, EE; Goswami, M; Wilke, KE1
Andis, SL; Bewley, JR; Boder, GB; Burke, T; Dudley, DE; Eichelberger, LE; Grindey, GB; Grossman, CS; Hertel, LW; Jordan, CL1
Benseler, F; Eckstein, F; Ng, MM; Tuschl, T1
Bailly, C; Payet, D; Travers, AA; Waring, MJ1
Boudinot, FD; Chu, CK; Manouilov, KK; Manouilova, LS; Schinazi, RF1
Bowlin, TL; de Muys, JM; Gu, Z; L'Heureux, L; Nguyen-Ba, N; Rando, RF; Wainberg, MA1
Hall, KB; Jean, JM1
Osman, R; Rachofsky, EL; Ross, JB1
Doudna, JA; Rich, A; Szostak, JW; Usman, N1
Grahn, E; Helgstrand, C; Liljas, L; Moss, T; Stockley, PG; Stonehouse, NJ; Tars, K1
Douglas, KT; Fedorova, OS; Koval, VV; Kuznetsov, NA; Nevinsky, GA; Zharkov, DO1
Arico, JW; Calhoun, AK; McLaughlin, LW1
Greenberg, MM; Hiemstra, CN; Sczepanski, JT1
Das, R; Mély, Y; Sharma, R; Shin, D; Sholokh, M; Tor, Y; Zaporozhets, OA1

Other Studies

14 other study(ies) available for 2-aminopurine and guanosine

ArticleYear
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship

2017
Medicinal chemistry of difluoropurines.
    Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 11

    Topics: 2-Aminopurine; Animals; Antineoplastic Agents; Blood Cell Count; Blood Pressure; Deoxyadenosines; Deoxyguanosine; Dogs; Drug Screening Assays, Antitumor; Female; Guanosine; Heart; Humans; In Vitro Techniques; Infusions, Intravenous; Injections, Intraperitoneal; Liver; Lymphoid Tissue; Male; Mice; Neoplasms, Experimental; Ovarian Neoplasms; Structure-Activity Relationship; Testis

1995
Isoguanosine substitution of conserved adenosines in the hammerhead ribozyme.
    Biochemistry, 1994, Oct-11, Volume: 33, Issue:40

    Topics: 2-Aminopurine; Adenosine; Amidines; Base Sequence; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Guanosine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; RNA, Catalytic; Structure-Activity Relationship; Trypsin Inhibitors

1994
PCR-based development of DNA substrates containing modified bases: an efficient system for investigating the role of the exocyclic groups in chemical and structural recognition by minor groove binding drugs and proteins.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Nov-26, Volume: 93, Issue:24

    Topics: 2-Aminopurine; Base Composition; Base Sequence; Binding Sites; Deoxyribonuclease I; Distamycins; DNA; DNA Footprinting; DNA Primers; Guanosine; High Mobility Group Proteins; Hydrogen Bonding; Inosine; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Plicamycin; Polymerase Chain Reaction

1996
Biotransformation and pharmacokinetics of prodrug 9-(beta-D-1,3-dioxolan-4-yl)-2-aminopurine and its antiviral metabolite 9-(beta-D-1,3-dioxolan-4-yl)guanine in mice.
    Antiviral research, 1997, Volume: 35, Issue:3

    Topics: 2-Aminopurine; Administration, Oral; Allopurinol; Animals; Biotransformation; Brain Chemistry; Dioxolanes; Drug Interactions; Female; Guanine; Guanosine; Injections, Intravenous; Liver; Mice; Prodrugs; Purines; Xanthine Oxidase

1997
Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:10

    Topics: 2-Aminopurine; Anti-HIV Agents; Cells, Cultured; Dioxolanes; Drug Interactions; Drug Resistance, Microbial; Guanosine; HIV Reverse Transcriptase; HIV-1; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests

1999
2-Aminopurine fluorescence quenching and lifetimes: role of base stacking.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-02, Volume: 98, Issue:1

    Topics: 2-Aminopurine; Adenosine; Algorithms; Base Pairing; Computer Simulation; DNA; Fluorescence; Guanosine; Hydrogen Bonding; Kinetics; Models, Molecular; Pyrimidine Dimers

2001
Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence.
    Biochemistry, 2001, Jan-30, Volume: 40, Issue:4

    Topics: 2-Aminopurine; Adenosine; Adenosine Triphosphate; Antimetabolites; Cytidine; DNA; Guanosine; Guanosine Triphosphate; Hydrogen Bonding; Kinetics; Models, Chemical; Quantum Theory; Solutions; Solvents; Spectrometry, Fluorescence; Structure-Activity Relationship; Thermodynamics; Thymidine; Titrimetry

2001
Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function.
    The Journal of organic chemistry, 1990, Oct-12, Volume: 55, Issue:21

    Topics: 2-Aminopurine; Animals; Directed Molecular Evolution; Guanosine; Molecular Biology; Molecular Structure; Oligoribonucleotides; Ribonucleosides; RNA, Catalytic; Substrate Specificity; Tetrahymena

1990
Investigating the structural basis of purine specificity in the structures of MS2 coat protein RNA translational operator hairpins.
    Nucleic acids research, 2002, Jun-15, Volume: 30, Issue:12

    Topics: 2-Aminopurine; Adenosine; Amino Acid Substitution; Base Sequence; Binding Sites; Capsid; Capsid Proteins; Cytidine; Guanosine; Hydrogen Bonding; Inosine; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Protein Biosynthesis; Purines; RNA-Binding Proteins; RNA-Dependent RNA Polymerase; RNA, Viral

2002
Kinetic conformational analysis of human 8-oxoguanine-DNA glycosylase.
    The Journal of biological chemistry, 2007, Jan-12, Volume: 282, Issue:2

    Topics: 2-Aminopurine; Catalysis; Cytosine; DNA Glycosylases; DNA Repair; Enzyme Activation; Guanine; Guanosine; Humans; Kinetics; Ligands; Nucleotides; Protein Conformation; Reactive Oxygen Species; Substrate Specificity

2007
Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation.
    The Journal of organic chemistry, 2010, Mar-05, Volume: 75, Issue:5

    Topics: 2-Aminopurine; Adenosine; Glycosylation; Guanine; Guanosine; Molecular Structure; Nucleosides; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship

2010
Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides.
    Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19

    Topics: 2-Aminopurine; Adenosine; Catalysis; Cross-Linking Reagents; DNA; Guanosine; Models, Molecular; Oxidation-Reduction; Tubercidin

2011
Conquering 2-aminopurine's deficiencies: highly emissive isomorphic guanosine surrogate faithfully monitors guanosine conformation and dynamics in DNA.
    Journal of the American Chemical Society, 2015, Mar-11, Volume: 137, Issue:9

    Topics: 2-Aminopurine; Binding Sites; DNA, Viral; Fluorescence Polarization; Guanosine; HIV-1; Nucleic Acid Heteroduplexes; Pyrimidinones; Spectrometry, Fluorescence; Thiophenes

2015