Page last updated: 2024-08-21

2-aminopurine and guanine

2-aminopurine has been researched along with guanine in 122 studies

Research

Studies (122)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (9.84)	18.7374
1990's	39 (31.97)	18.2507
2000's	41 (33.61)	29.6817
2010's	29 (23.77)	24.3611
2020's	1 (0.82)	2.80

Authors

Authors	Studies
Brereton, IM; de Jersey, J; Guddat, LW; Jones, MK; Keough, DT; Ng, AL; Skinner-Adams, T	1
Chaudhary, D; Chauhan, V; Dhaked, RK; Pathak, U; Saxena, N	1
Carlson, EE; Goswami, M; Wilke, KE	1
Kocharian, ShM	1
Boyd, MR; Harnden, MR; Jarvest, RL; Sutton, D; Vere Hodge, RA	2
Goodman, MF; Hopkins, RL; Lasken, R; Mhaskar, DN	1
Clifford, AJ; Clifford, CK; Ho, YK; Koehn, DJ; Sobieski, RJ	1
Garber, BB; Gots, JS	1
Bailly, C; Travers, AA; Waring, MJ	1
Duggan, LJ; Garrison, K; Gottlieb, PA; Hill, TM; Wu, S; Zhang, X	1
Beigelman, L; Cech, TR; Strobel, SA; Usman, N	1
Bailly, C; Waring, MJ	2
Allen, GD; Brown, TA; Filer, CW; Fowles, SE; Hollis, FJ; Mort, EE; Ramji, JV	1
Chenery, RJ; Clarke, SE; Harrell, AW	1
Audet, PR; Boike, SC; Fairless, A; Freed, MI; Ilson, BE; Jorkasky, DK; Pue, M; Zariffa, N	1
Day, RS; Xu, YZ	1
Fowles, SE; Laroche, J; Pratt, SK; Prince, WT	1
Maung, M; Slomka, MJ; Tsiquaye, KN	1
Acedo, M; Aviño, A; Eritja, R; Fàbrega, C; Fagan, P; Goodman, M; Wemmer, D	1
Fairless, AJ; Fowles, S; Georgiou, P; Laroche, J; Pratt, SK; Prince, W; Pue, MA	1
Darlison, SJ; Readshaw, SA; Vere Hodge, RA	1
Rolan, P	1
Sacks, SL	1
Schacke, M; Thust, R; Wutzler, P	1
Whitley, RJ	2
Crumpacker, C	1
Reusser, P	1
Beigelman, L; Herschlag, D; Peracchi, A; Usman, N	1
Fowler, SL; Goade, D; Kraus, SJ; Levin, MJ; Loveless, MO; Mertz, GJ; Tyring, SK	1
Cassady, KA; Whitley, RJ	1
Dubois, S; Eritja, R; Guschlbauer, W; Thielking, V	1
Boudinot, FD; Chu, CK; Manouilov, KK; Manouilova, LS; Schinazi, RF	1
Marks, L; Saltzman, R	1
Gremaud, E; Markovic, J; Ravanat, JL; Turesky, RJ	1
Jaeckel, E; Manns, MP	1
Barton, JK; Kelley, SO	1
Evdokimov, AA; Hattman, S; Jen-Jacobson, L; Kossykh, VG; Malygin, EG; Petrov, NA; Zinoviev, VV	1
Benfeldt, E; Borg, N; Götharson, E; Groth, L; Ståhle, L	1
Sacks, SL; Wilson, B	1
Keating, MR	1
Bradley, RK; Colbert, DT; Hardin, SH; Jones, LB; Reddy, MS; Smalley, RE; Ying, J	1
Déclais, AC; Lilley, DM	1
Bengis, RG; Cambre, RC; Hamzeh, FM; Hardy, D; Hayward, GS; Hildbrandt, T; Montali, RJ; Richman, LK; Schmitt, D; Shahkolahi, A	1
Allinson, SL; Brown, T; Fox, KR; Sahagun-Krause, H	1
Barton, JK; Fiebig, T; Schiemann, O; Wan, C; Zewail, AH	1
Blum, HE; Hafkemeyer, P; Keppler-Hafkemeyer, A; Offensperger, S; Offensperger, WB	1
Burke, JM; Chan, PA; Hampel, KJ; Millar, DP; Walter, NG	1
Kontogiannis, L; Lilley, DM; Maxwell, K; Wilson, TJ; Zhao, ZY	1
Kozlov, IA; Orgel, LE	1
Dekker, CL; Prober, CG	1
de Man, RA; Niesters, HG; Wolters, LM	1
De Clercq, E; Naesens, L	1
Field, HJ; Gürr, WK; Littler, E; Shaw, MM; Thackray, AM; Watts, PA	1
Bossi, P	1
Brown, TJ; McCrary, M; Tyring, SK	1
Hall, KB; Jean, JM	1
Dvoráková, H; Kubelka, V; Linhart, I; Novák, J	1
Cairns, MJ; King, A; Sun, LQ	1
DUNCAN, RE; SETTERFIELD, G	1
HOWARD, BD; TESSMAN, I	1
GUTHRIE, R; LU, WC	1
Doláková, P; Holý, A; Masojídková, M	1
Kawai, K; Kimura, T; Majima, T	1
Barton, JK; Dohno, C; O'Neill, MA	1
MORGAN, HR	1
Arent, S; Frieden, M; Jensen, FR; Koch, T; Larsen, S; Pedersen, DS; Rosenbohm, C	1
Avci, A; Erhardt, A; Häussinger, D; Heintges, T; Lörke, J; Sagir, A	1
Andrei, G; De Clercq, E; Snoeck, R	1
Barton, JK; O'Neill, MA	1
BENDICH, A; BROWN, GB; FURST, SS	1
Beutner, K; Chakrabarty, A; Rauser, M; Tyring, SK	1
Crean, C; Geacintov, NE; Misiaszek, R; Shafirovich, V	1
Chaires, JB; Correia, JJ; Li, J; Trent, JO; Wang, L	1
Arar, K; Gamper, HB; Gewirtz, A; Hou, YM	1
Batey, RT; Gilbert, SD; Stoddard, CD; Wise, SJ	1
Abdel-Haq, N; Al-Tatari, H; Asmar, B; Chearskul, P	1
Hijiya, T; Izawa, K; Kojima, M; Suzuki, Y; Torii, T; Yamashita, K	1
Kool, ET; Lai, J; Shuman, S; Yakovleva, L	1
Aldern, KA; Beadle, JR; Hartline, CB; Hostetler, KY; Kern, ER; Ruiz, JC	1
Douglas, KT; Fedorova, OS; Koval, VV; Kuznetsov, NA; Nevinsky, GA; Zharkov, DO	1
Lafontaine, DA; Mulhbacher, J	1
Maggs, DJ; Moulin, NK; Stanley, SD; Thomasy, SM	1
BONDICH, A; BROWN, GB	1
Matsika, S; Mburu, E	1
Xia, T; Zhao, L	1
Ivanova, E; Wang, F; Zhu, Q	1
Kondo, T; Kurosawa, M; Matsumura, T; Nagata, S; Nemoto, M; Tsujimura, K; Yamada, M; Yamanaka, T	1
Arico, JW; Calhoun, AK; McLaughlin, LW	1
Blumer, J; Hamed, K; Kaiser, G; Rodriguez, A; Sallas, W; Sánchez, PJ	1
Jain, N; Liu, JD; Xia, T; Zhao, L	1
Blaustein, GS; Burin, AL; Lewis, FD	1
Kankia, BI	1
Dumas, A; Luedtke, NW	1
Crégut, O; Gelot, T; Haacke, S; Léonard, J; Tourón-Touceda, P	1
Covert, JC; Maggs, DJ; Stanley, SD; Thomasy, SM	1
Geacintov, NE; Liu, Y; Liu, Z; Shafirovich, V	1
Bales, JL; Ferrone, M; Maggs, DJ; Stanley, SD; Thomasy, SM; Whittem, T	1
Brock, AP; Hunter, RP; Isaza, R; Koch, DE; Lindsay, WA; Montali, RJ; Richman, LK; Schmitt, DL	1
Gogichaishvili, S; Joseph, A; Kankia, B; Musier-Forsyth, K; Okyere, R; Taylor, A	1
Baglivo, E; Csajka, C; Daali, Y; Dayer, P; Gex-Fabry, M; Kondo-Oestreicher, M; Schenkel, F	1
Liang, J; Matsika, S; Nguyen, QL	1
Contreras, MT; Groth, AD; Kado-Fong, HK; Maggs, DJ; Nguyen, KQ; Thomasy, SM	1
Belogurov, GA; Malinen, AM; Turtola, M	1
Buechner, CN; Drohat, AC; Maiti, A; Tessmer, I	1
Horvath, A; Qiu, R; Stahlmann, R	1
Knych, HK; Maggs, DJ; Sebbag, L; Thomasy, SM; Woodward, AP	1
Fujimoto, K; Ooe, M; Sakamoto, T; Sethi, S	1
Jeong, LS; Kim, G; Naik, SD; Qu, S; Sahu, PK; Umme, T; Yu, J	1
Mondal, S; Puranik, M	1
Kamble, NR; Sigurdsson, ST	1
Bull, GD; Thompson, KC	1
Hornum, M; Kumar, P; Nielsen, P; Nielsen, RB; Petersen, M; Sharma, PK; Stendevad, J	1
Chen, J; Pang, L; Wang, X; Zhang, JZH; Zhu, T	1
Chatterjee, S; Daher, M; Lund, PE; Walter, NG	1

Reviews

19 review(s) available for 2-aminopurine and guanine

Article	Year
Pharmacokinetics of new antiherpetic agents. Clinical pharmacokinetics, 1995, Volume: 29, Issue:5 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Famciclovir; Guanine; Herpesviridae Infections; Humans; Prodrugs; Valacyclovir; Valine	1995
Use of penciclovir and famciclovir in the management of genital herpes. Current problems in dermatology, 1996, Volume: 24 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Guanine; Herpes Genitalis; Humans; Recurrence	1996
Advances in the management of herpesvirus infections. Introduction. Seminars in dermatology, 1996, Volume: 15, Issue:2 Suppl 1 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Guanine; Herpes Zoster; Herpesviridae Infections; Humans	1996
The pharmacological profile of famciclovir. Seminars in dermatology, 1996, Volume: 15, Issue:2 Suppl 1 Topics: 2-Aminopurine; Acyclovir; Aged; Antiviral Agents; Drug Interactions; Famciclovir; Guanine; Herpes Zoster; Humans	1996
Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options. The Journal of hospital infection, 1996, Volume: 33, Issue:4 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine	1996
New therapeutic approaches to the alphaherpesvirus infections. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2 Topics: 2-Aminopurine; Acyclovir; Alphaherpesvirinae; Antibodies, Monoclonal; Arabinofuranosyluracil; Cidofovir; Cytosine; Famciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine	1997
Experience with lamivudine against hepatitis B virus. Intervirology, 1997, Volume: 40, Issue:5-6 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Famciclovir; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Interferons; Lamivudine; Liver Transplantation; Mutation; Nucleosides; Reverse Transcriptase Inhibitors	1997
Famciclovir/penciclovir. Advances in experimental medicine and biology, 1999, Volume: 458 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Guanine; Herpes Genitalis; Herpes Labialis; Herpes Simplex; Herpes Zoster; Herpesvirus 3, Human; Humans; Immunocompromised Host; Prodrugs; Simplexvirus; Virus Replication	1999
Antiviral agents for non-human immunodeficiency virus infections. Mayo Clinic proceedings, 1999, Volume: 74, Issue:12 Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir	1999
Approaches to the treatment of varicella-zoster virus infections. Contributions to microbiology, 1999, Volume: 3 Topics: 2-Aminopurine; Acyclovir; Adrenal Cortex Hormones; Antiviral Agents; Chickenpox; Famciclovir; Guanine; Herpes Zoster; Humans; Immunocompromised Host; Prodrugs; Valacyclovir; Valine	1999
Pediatric uses of valacyclovir, penciclovir and famciclovir. The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Child; Drug Approval; Famciclovir; Guanine; Herpesviridae Infections; Humans; Immunocompetence; United States; United States Food and Drug Administration; Valacyclovir; Valine	2001
Nucleoside analogues for chronic hepatitis B. European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:12 Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Ganciclovir; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors	2001
Recent developments in herpesvirus therapy. Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:1 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine	2001
[Genital herpes: epidemiology, transmission, clinic, asymptomatic viral excretion, impact on other sexually transmitted diseases, prevention, and treatment]. Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:4 Pt 2 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Drug Therapy, Combination; Famciclovir; Female; France; Guanine; Herpes Genitalis; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Male; Patient Education as Topic; Risk Factors; Valacyclovir; Valine; Virus Shedding	2002
Antiviral agents: Non-antiretroviral [correction of Nonantiviral] drugs. Journal of the American Academy of Dermatology, 2002, Volume: 47, Issue:4 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Chickenpox; Cytomegalovirus Infections; Famciclovir; Foscarnet; Guanine; Hepatitis B; Hepatitis C; Herpes Genitalis; Herpes Simplex; Herpesvirus 3, Human; Herpesvirus 8, Human; Humans; Papillomavirus Infections; Sarcoma, Kaposi; Skin Diseases, Viral; Valacyclovir; Valine	2002
[New approaches in the treatment of hepatitis B]. Deutsche medizinische Wochenschrift (1946), 2004, May-21, Volume: 129, Issue:21 Topics: 2-Aminopurine; Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Contraindications; Deoxycytidine; Emtricitabine; Famciclovir; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Organophosphorus Compounds; Polyethylene Glycols; Prodrugs; Prognosis; Recombinant Proteins; Tenofovir; Zalcitabine	2004
Recent clinical experience with famciclovir--a "third generation" nucleoside prodrug. Antiviral chemistry & chemotherapy, 2004, Volume: 15, Issue:5 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Biological Availability; Clinical Trials as Topic; Famciclovir; Guanine; Herpes Genitalis; Herpes Zoster; Humans; Male; Nervous System; Prodrugs	2004
New antiviral agents. Indian journal of pediatrics, 2006, Volume: 73, Issue:4 Topics: 2-Aminopurine; Acyclovir; Aminoquinolines; Antiviral Agents; Bromodeoxyuridine; Famciclovir; Fatty Alcohols; Ganciclovir; Guanine; Humans; Imiquimod; Valganciclovir; Virus Diseases	2006
Probing RNA conformational dynamics and heterogeneity using femtosecond time-resolved fluorescence spectroscopy. Methods (San Diego, Calif.), 2009, Volume: 49, Issue:2 Topics: 2-Aminopurine; Adenine; Anisotropy; Equipment Design; Guanine; Models, Molecular; Models, Statistical; Molecular Conformation; Molecular Structure; Nucleic Acid Conformation; RNA; RNA, Viral; Spectrometry, Fluorescence; Time Factors	2009

Trials

7 trial(s) available for 2-aminopurine and guanine

Article	Year
Linear pharmacokinetics of penciclovir following administration of single oral doses of famciclovir 125, 250, 500 and 750 mg to healthy volunteers. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:1 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Famciclovir; Guanine; Half-Life; Humans; Male; Middle Aged; Prodrugs; Single-Blind Method; Spectrophotometry, Ultraviolet	1994
Oral famciclovir for suppression of recurrent genital herpes simplex virus infection in women. A multicenter, double-blind, placebo-controlled trial. Collaborative Famciclovir Genital Herpes Research Group. Archives of internal medicine, 1997, Feb-10, Volume: 157, Issue:3 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Antigen-Antibody Complex; Antiviral Agents; Double-Blind Method; Famciclovir; Female; Guanine; Herpes Genitalis; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Recurrence; Simplexvirus; Treatment Outcome	1997
Distribution to the skin of penciclovir after oral famciclovir administration in healthy volunteers: comparison of the suction blister technique and cutaneous microdialysis. Acta dermato-venereologica, 1999, Volume: 79, Issue:4 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Antiviral Agents; Blister; Dialysis Solutions; Epinephrine; Famciclovir; Female; Guanine; Humans; Male; Microdialysis; Prodrugs; Skin; Temperature; Time Factors; Tissue Distribution; Vasoconstrictor Agents	1999
Pharmacokinetics and safety of penciclovir following oral administration of famciclovir to cats. American journal of veterinary research, 2007, Volume: 68, Issue:11 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Cats; Cross-Over Studies; Drug Interactions; Famciclovir; Female; Guanine; Half-Life; Prodrugs; Specific Pathogen-Free Organisms	2007
Single-dose pharmacokinetics of famciclovir in infants and population pharmacokinetic analysis in infants and children. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Antiviral Agents; Body Weight; Capsules; Child; Child, Preschool; Famciclovir; Female; Guanine; Herpes Simplex; Humans; Infant, Newborn; Male; Models, Biological	2010
Pharmacokinetics of famciclovir and penciclovir in tears following oral administration of famciclovir to cats: a pilot study. Veterinary ophthalmology, 2012, Volume: 15, Issue:5 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Antiviral Agents; Cats; Dose-Response Relationship, Drug; Eye Diseases; Famciclovir; Guanine; Herpesviridae Infections; Pilot Projects; Specimen Handling; Tears	2012
Pharmacokinetic modeling of penciclovir and BRL42359 in the plasma and tears of healthy cats to optimize dosage recommendations for oral administration of famciclovir. American journal of veterinary research, 2016, Volume: 77, Issue:8 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Cats; Cross-Over Studies; Dose-Response Relationship, Drug; Famciclovir; Guanine; Male; Specific Pathogen-Free Organisms; Tears	2016

Other Studies

96 other study(ies) available for 2-aminopurine and guanine

Article	Year
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases. Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25 Topics: Animals; Antimalarials; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Pentosyltransferases; Plasmodium falciparum; Purines; Structure-Activity Relationship	2006
In Silico Discovery and Validation of Amide Based Small Molecule Targeting the Enzymatic Site of Shiga Toxin. Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23 Topics: Amides; Animals; Cells, Cultured; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Discovery; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Shiga Toxin; Small Molecule Libraries; Structure-Activity Relationship; Vero Cells	2016
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases. Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19 Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship	2017
[Genetic control of Escherichia coli K-12 strains' assimilation of 2,6-diaminopurine as a purine source]. Genetika, 1977, Volume: 13, Issue:7 Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Escherichia coli; Guanine; Hypoxanthines; Mutation; Transduction, Genetic	1977
Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir]. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:10 Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Bile; Biological Availability; Chromatography, High Pressure Liquid; Duodenum; Famciclovir; Guanine; Humans; In Vitro Techniques; Intestinal Mucosa; Liver; Male; Prodrugs; Rats; Tissue Distribution	1989
Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties. Journal of medicinal chemistry, 1989, Volume: 32, Issue:8 Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Famciclovir; Guanine; Intestinal Absorption; Mice; Prodrugs	1989
The biochemical basis of 5-bromouracil- and 2-aminopurine-induced mutagenesis. Basic life sciences, 1985, Volume: 31 Topics: 2-Aminopurine; Adenine; Base Composition; Bromouracil; Cytosine; Deoxycytosine Nucleotides; Deoxyribonucleotides; Deoxyuracil Nucleotides; Guanine; Mutation; Nucleic Acid Heteroduplexes; Thymine	1985
Effects of purine amino groups on the development of Drosophila. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:2 Topics: 2-Aminopurine; Adenine; Animals; Charcoal; Drosophila melanogaster; Guanine; Larva; Purines	1984
Utilization of 2,6-diaminopurine by Salmonella typhimurium. Journal of bacteriology, 1980, Volume: 143, Issue:2 Topics: 2-Aminopurine; Adenine; Adenosine Deaminase; Guanine; Mutation; Purine-Nucleoside Phosphorylase; Purines; Salmonella typhimurium	1980
Effects of base substitutions on the binding of a DNA-bending protein. Journal of molecular biology, 1995, Oct-13, Volume: 253, Issue:1 Topics: 2-Aminopurine; Base Sequence; Carrier Proteins; DNA Footprinting; DNA-Binding Proteins; DNA, Bacterial; Factor For Inversion Stimulation Protein; Guanine; Inosine; Integration Host Factors; Molecular Sequence Data; Nucleic Acid Conformation; Promoter Regions, Genetic; RNA, Transfer, Tyr	1995
Using modified nucleotides to map the DNA determinants of the Tus-TerB complex, the protein-DNA interaction associated with termination of replication in Escherichia coli. The Journal of biological chemistry, 1995, Nov-24, Volume: 270, Issue:47 Topics: 2-Aminopurine; Bacterial Proteins; Base Sequence; Binding Sites; Binding, Competitive; Calorimetry; Deoxyribonucleotides; DNA Replication; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli Proteins; Genes, Bacterial; Guanine; Hydrogen Bonding; Inosine; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Structure-Activity Relationship; Terminator Regions, Genetic; Thymine; Uracil	1995
The 2,6-diaminopurine riboside.5-methylisocytidine wobble base pair: an isoenergetic substitution for the study of G.U pairs in RNA. Biochemistry, 1994, Nov-22, Volume: 33, Issue:46 Topics: 2-Aminopurine; Amides; Base Composition; Base Sequence; Cytidine; Guanine; Molecular Sequence Data; Phosphoric Acids; RNA; Thermodynamics; Uridine	1994
The purine 2-amino group as a critical recognition element for binding of small molecules to DNA. Gene, 1994, Nov-04, Volume: 149, Issue:1 Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Autoradiography; Base Sequence; Dactinomycin; Deoxyribonuclease I; DNA; Echinomycin; Guanine; Inosine; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; RNA, Transfer, Tyr	1994
Metabolic and pharmacokinetic studies following oral administration of famciclovir to the rat and dog. Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:5 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Biotransformation; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Famciclovir; Feces; Guanine; Male; Mass Spectrometry; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrophotometry, Ultraviolet	1995
Transferring the purine 2-amino group from guanines to adenines in DNA changes the sequence-specific binding of antibiotics. Nucleic acids research, 1995, Mar-25, Volume: 23, Issue:6 Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Dinucleoside Phosphates; DNA; Guanine; Inosine; Intercalating Agents; Ligands; Molecular Sequence Data; Peptides; RNA, Transfer, Tyr	1995
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver. Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:2 Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Antiviral Agents; Benzaldehydes; Cytosol; Famciclovir; Guanine; Humans; Kinetics; Liver; Oxidation-Reduction; Prodrugs; Vitamin K; Xanthine Oxidase	1995
Pharmacokinetics of famciclovir in subjects with chronic hepatic disease. Journal of clinical pharmacology, 1994, Volume: 34, Issue:12 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adolescent; Adult; Biological Availability; Chromatography, High Pressure Liquid; Chronic Disease; Famciclovir; Female; Guanine; Humans; Liver Diseases; Male; Metabolic Clearance Rate; Middle Aged; Prodrugs	1994
Incision at diaminopurine: thymine base pairs but not at guanine:O4-methylthymine base pairs in DNA by extracts of human cells. Biochemistry, 1995, Jun-06, Volume: 34, Issue:22 Topics: 2-Aminopurine; Base Composition; Base Sequence; Cell Line; Cell-Free System; DNA; Glioma; Guanine; Humans; Hydrogen Bonding; Molecular Sequence Data; Oligodeoxyribonucleotides; Thymine; Tumor Cells, Cultured	1995
Lack of a pharmacokinetic interaction between oral famciclovir and allopurinol in healthy volunteers. European journal of clinical pharmacology, 1994, Volume: 46, Issue:4 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Allopurinol; Antiviral Agents; Drug Interactions; Famciclovir; Guanine; Half-Life; Humans; Male; Middle Aged; Oxypurinol	1994
Oral famciclovir against duck hepatitis B virus replication in hepatic and nonhepatic tissues of ducklings infected in ovo. Journal of medical virology, 1994, Volume: 42, Issue:3 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Animals, Newborn; Antiviral Agents; Biotransformation; Disease Models, Animal; DNA, Viral; Ducks; Eggs; Famciclovir; Guanine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Kidney; Liver; Organ Specificity; Pancreas; Poultry Diseases; Prodrugs; Spleen; Viremia; Virus Replication; Xanthine Oxidase	1994
A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides. Nucleic acids research, 1994, Aug-11, Volume: 22, Issue:15 Topics: 2-Aminopurine; Adenine; Ammonia; Base Sequence; Chromatography, High Pressure Liquid; Cytosine; Guanine; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes; Oligodeoxyribonucleotides	1994
Use of isotopically chiral [4'-13C]famciclovir and 13C NMR to identify the chiral monoacetylated intermediates in the conversion of famciclovir to penciclovir by human intestinal wall extract. Chirality, 1993, Volume: 5, Issue:8 Topics: 2-Aminopurine; Acetylation; Acyclovir; Antiviral Agents; Biotransformation; Carbon Isotopes; Famciclovir; Guanine; Humans; In Vitro Techniques; Intestine, Small; Magnetic Resonance Spectroscopy; Prodrugs; Stereoisomerism; Tissue Extracts	1993
Cytogenetic genotoxicity of antiherpes virostatics in Chinese hamster V79-E cells. I. Purine nucleoside analogues. Antiviral research, 1996, Volume: 31, Issue:1-2 Topics: 2-Aminopurine; Acyclovir; Animals; CHO Cells; Cricetinae; Famciclovir; Ganciclovir; Guanine; Mutagenicity Tests; Mutagens; Valacyclovir; Valine	1996
Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases. Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-15, Volume: 93, Issue:21 Topics: 2-Aminopurine; Base Composition; Base Sequence; Guanine; Hypoxanthine; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; Oligoribonucleotides; RNA, Catalytic	1996
Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers: nonmethylated substrates. Biological chemistry, 1997, Volume: 378, Issue:5 Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Methylation; DNA Probes; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Guanine; Hypoxanthine; Kinetics; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligonucleotide Probes; Site-Specific DNA-Methyltransferase (Adenine-Specific); Software; Substrate Specificity; Temperature; Thermodynamics; Thymine; Uracil	1997
Drugs for non-HIV viral infections. The Medical letter on drugs and therapeutics, 1997, Aug-01, Volume: 39, Issue:1006 Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases	1997
Biotransformation and pharmacokinetics of prodrug 9-(beta-D-1,3-dioxolan-4-yl)-2-aminopurine and its antiviral metabolite 9-(beta-D-1,3-dioxolan-4-yl)guanine in mice. Antiviral research, 1997, Volume: 35, Issue:3 Topics: 2-Aminopurine; Administration, Oral; Allopurinol; Animals; Biotransformation; Brain Chemistry; Dioxolanes; Drug Interactions; Female; Guanine; Guanosine; Injections, Intravenous; Liver; Mice; Prodrugs; Purines; Xanthine Oxidase	1997
Contempo 1997: dermatology. JAMA, 1997, Oct-08, Volume: 278, Issue:14 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Guanine; Herpes Labialis; Herpes Zoster; Humans; Valacyclovir; Valine	1997
Detection of 8-oxoguanine in cellular DNA using 2,6-diamino-8-oxopurine as an internal standard for high-performance liquid chromatography with electrochemical detection. Analytical biochemistry, 1998, Jun-15, Volume: 260, Issue:1 Topics: 2-Aminopurine; Animals; Artifacts; Chromatography, High Pressure Liquid; Colon; DNA; Electrochemistry; Ferric Compounds; Guanine; Hydrolysis; Kidney; Liver; Male; Nitrilotriacetic Acid; Organ Specificity; Oxidation-Reduction; Rats; Rats, Sprague-Dawley	1998
Electron transfer between bases in double helical DNA. Science (New York, N.Y.), 1999, Jan-15, Volume: 283, Issue:5400 Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Electrons; Guanine; Hydrogen Bonding; Kinetics; Light; Nucleic Acid Conformation; Oxidation-Reduction; Spectrometry, Fluorescence; Thermodynamics	1999
Effect of base analog substitutions in the specific GATC site on binding and methylation of oligonucleotide duplexes by the bacteriophage T4 Dam DNA-[N6-adenine] methyltransferase. Nucleic acids research, 1999, Feb-15, Volume: 27, Issue:4 Topics: 2-Aminopurine; Adenine; Bacteriophage T4; Binding Sites; DNA Methylation; Guanine; Kinetics; Mutagenesis, Site-Directed; Oligonucleotides; Purines; Site-Specific DNA-Methyltransferase (Adenine-Specific); Viral Proteins	1999
Guanine-rich telomeric sequences stimulate DNA polymerase activity in vitro. Biochemistry, 1999, Dec-14, Volume: 38, Issue:50 Topics: 2-Aminopurine; Animals; Base Pairing; Deoxyguanine Nucleotides; DNA; DNA Replication; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; Hypotrichida; Oligonucleotides; Saccharomyces cerevisiae; Sequence Analysis, DNA; Telomere; Tetrahymena	1999
Extensive central disruption of a four-way junction on binding CCE1 resolving enzyme. Journal of molecular biology, 2000, Feb-18, Volume: 296, Issue:2 Topics: 2-Aminopurine; Base Pairing; Base Sequence; DNA; DNA Footprinting; Endodeoxyribonucleases; Fluorescence; Guanine; Holliday Junction Resolvases; Models, Genetic; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Potassium Permanganate; Recombinant Proteins; Recombination, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spectrometry, Fluorescence; Temperature; Thymine	2000
Clinical and pathological findings of a newly recognized disease of elephants caused by endotheliotropic herpesviruses. Journal of wildlife diseases, 2000, Volume: 36, Issue:1 Topics: 2-Aminopurine; Acyclovir; Animals; Animals, Zoo; Antiviral Agents; DNA, Viral; Elephants; Endothelium, Vascular; Famciclovir; Female; Guanine; Herpesviridae; Herpesviridae Infections; Liver; Lung; Male; Myocardium; North America; Polymerase Chain Reaction; Prodrugs; Retrospective Studies; Tongue	2000
Recognition of GT mismatches by Vsr mismatch endonuclease. Nucleic acids research, 2000, 07-01, Volume: 28, Issue:13 Topics: 2-Aminopurine; Base Pair Mismatch; Base Pairing; Base Sequence; Deoxyuridine; DNA; Endodeoxyribonucleases; Escherichia coli; Guanine; Kinetics; Purine Nucleosides; Ribonucleosides; Substrate Specificity; Thymine; Toluene	2000
Drugs for non-HIV viral infections. The Medical letter on drugs and therapeutics, 1999, Dec-03, Volume: 41, Issue:1067 Topics: 2-Aminopurine; Acetamides; Acyclovir; Aged; Amantadine; Animals; Anti-HIV Agents; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Enzyme Inhibitors; Famciclovir; Ganciclovir; Guanidines; Guanine; Herpes Simplex; Herpes Zoster; History, 18th Century; HIV Infections; Humans; Injections, Intravenous; Interferon-alpha; Lamivudine; Neuraminidase; Oseltamivir; Pyrans; Rats; Ribavirin; Sialic Acids; Teratogens; Valacyclovir; Valine; Zanamivir	1999
Herpes drugs fetch R11.4 bil. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2000, Volume: 90, Issue:10 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Drug Industry; Famciclovir; Guanine; Humans; South Africa	2000
Femtosecond direct observation of charge transfer between bases in DNA. Proceedings of the National Academy of Sciences of the United States of America, 2000, Dec-19, Volume: 97, Issue:26 Topics: 2-Aminopurine; Adenine; Base Pairing; DNA; Electron Transport; Guanine; Inosine; Models, Molecular; Time Factors	2000
Antiviral activities of penciclovir and famciclovir on duck hepatitis B virus in vitro and in vivo. Antiviral therapy, 1996, Volume: 1, Issue:3 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Ducks; Famciclovir; Guanine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Hepatocytes; Virus Replication	1996
A base change in the catalytic core of the hairpin ribozyme perturbs function but not domain docking. Biochemistry, 2001, Feb-27, Volume: 40, Issue:8 Topics: 2-Aminopurine; Base Composition; Catalysis; Catalytic Domain; Energy Transfer; Enzyme Stability; Guanine; Hydrolysis; Kinetics; Mutation; Nucleic Acid Conformation; RNA, Catalytic; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics; Uridine	2001
Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme. Biochemistry, 2001, Feb-20, Volume: 40, Issue:7 Topics: 2-Aminopurine; Adenine; Base Composition; Base Sequence; Carbocyanines; Cytosine; Deoxyribonucleosides; Energy Transfer; Fluorescein; Fluorescent Dyes; Guanine; Hydrolysis; Molecular Sequence Data; Nepovirus; Nucleic Acid Conformation; Oligonucleotides; Point Mutation; Purine Nucleotides; Ribose; RNA, Catalytic; Spectrometry, Fluorescence; Uridine	2001
Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues. Helvetica chimica acta, 1999, Volume: 82, Issue:11 Topics: 2-Aminopurine; Adenine; Adenosine; Adenosine Monophosphate; Base Pairing; Cytidine Monophosphate; Cytosine; DNA Primers; Evolution, Chemical; Evolution, Molecular; Exobiology; Guanine; Inosine Monophosphate; RNA; Templates, Genetic; Uracil; Uridine Monophosphate	1999
Drugs for non-HIV viral infections. The Medical letter on drugs and therapeutics, 2002, Feb-04, Volume: 44, Issue:1123 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Amantadine; Animals; Antiviral Agents; Cidofovir; Cytosine; Famciclovir; Foscarnet; Guanine; Herpesviridae Infections; Humans; Influenza, Human; Injections, Intravenous; Lamivudine; Organophosphonates; Organophosphorus Compounds; Rats; Ribavirin; Rimantadine; Thionucleotides; Trifluridine; Valacyclovir; Valine	2002
Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues. Journal of virological methods, 2002, Volume: 102, Issue:1-2 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Apoptosis; Brain Stem; Disease Models, Animal; DNA Fragmentation; Famciclovir; Female; Ganciclovir; Guanine; Herpes Simplex; Herpesvirus 1, Human; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Valacyclovir; Valine	2002
2-Aminopurine electronic structure and fluorescence properties in DNA. Biochemistry, 2002, Nov-05, Volume: 41, Issue:44 Topics: 2-Aminopurine; Dimerization; DNA; Electrons; Fluorescence Resonance Energy Transfer; Guanine; Models, Chemical; Models, Molecular; Purines; Pyrimidines; Thymine	2002
Synthesis of 7-hydroxy(phenyl)ethylguanines by alkylation of 2-amino-6-chloropurine with allyl-protected bromohydrins. Organic letters, 2003, Mar-06, Volume: 5, Issue:5 Topics: 2-Aminopurine; Alcohols; Alkylation; Allyl Compounds; DNA Adducts; Guanine	2003
Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites. Nucleic acids research, 2003, Jun-01, Volume: 31, Issue:11 Topics: 2-Aminopurine; Adenine; Base Pairing; Base Sequence; Catalysis; Cytosine; DNA, Catalytic; DNA, Single-Stranded; Guanine; Hydrogen Bonding; Kinetics; Nucleic Acid Conformation; RNA; RNA, Catalytic; Substrate Specificity	2003
Cytological studies on the antimetabolite action of 2, 6-diaminopurine in Vicia faba roots. The Journal of biophysical and biochemical cytology, 1955, Sep-25, Volume: 1, Issue:5 Topics: 2-Aminopurine; Adenine; Adenosine; Antimetabolites; Cell Division; Deoxyadenosines; DNA; Growth; Guanine; Hypoxanthine; Purines; Vicia faba	1955
IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. II. IN VIVO MUTAGENESIS BY 5-BROMODEOXYURIDINE AND 2-AMINOPURINE. Journal of molecular biology, 1964, Volume: 9 Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Bromodeoxyuridine; Coliphages; Cytosine; Cytosine Nucleotides; DNA; DNA, Single-Stranded; DNA, Viral; Guanine; Guanine Nucleotides; Mutagenesis; Mutation; Nucleosides; Purines; Research; Thymidine; Thymine	1964
ANTAGONISM BETWEEN PURINES IN PURINE-REQUIRING BACILLUS SUBTILIS MUTANTS. Archives of biochemistry and biophysics, 1964, Volume: 108 Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Azaguanine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Mercaptopurine; Metabolism; Mutation; Nucleosides; Nucleotides; Pharmacology; Purines; Research; Xanthines	1964
Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids. Nucleosides, nucleotides & nucleic acids, 2003, Volume: 22, Issue:12 Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Antiviral Agents; Butyrates; Guanine; Hypoxanthines; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Purines	2003
Fluorescence properties of 2-aminopurine-cytidine-7-deazaguanine (5'-ApCdzG-3') trimer in B- and Z-DNA. Chemical communications (Cambridge, England), 2004, Feb-07, Issue:3 Topics: 2-Aminopurine; Base Sequence; Cytidine; DNA, Z-Form; Electron Transport; Fluorescence; Guanine; Nucleic Acid Conformation; Sodium Chloride; Spectrometry, Fluorescence	2004
Direct chemical evidence for charge transfer between photoexcited 2-aminopurine and guanine in duplex DNA. Journal of the American Chemical Society, 2004, Feb-11, Volume: 126, Issue:5 Topics: 2-Aminopurine; Chromatography, High Pressure Liquid; DNA; Guanine; Photochemistry	2004
Factors related to the growth of psittacosis virus (strain 6BC) II. Purines, pyrimidines, and other components related to nucleic acid. The Journal of experimental medicine, 1952, Volume: 95, Issue:3 Topics: 2-Aminopurine; Adenine; Benzimidazoles; Guanine; Nucleic Acids; Psittacosis; Pterins; Purines; Pyrimidines	1952
LNA guanine and 2,6-diaminopurine. Synthesis, characterization and hybridization properties of LNA 2,6-diaminopurine containing oligonucleotides. Bioorganic & medicinal chemistry, 2004, May-01, Volume: 12, Issue:9 Topics: 2-Aminopurine; Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Hybridization; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization	2004
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir? Antiviral research, 2004, Volume: 61, Issue:3 Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins	2004
DNA charge transport: conformationally gated hopping through stacked domains. Journal of the American Chemical Society, 2004, Sep-22, Volume: 126, Issue:37 Topics: 2-Aminopurine; Base Pairing; Base Sequence; DNA; Guanine; Nucleic Acid Conformation; Oligonucleotides; Photochemistry; Spectrometry, Fluorescence; Static Electricity; Temperature	2004
On the role of 2,6-diaminopurine in the biosynthesis of nucleic acid guanine. The Journal of biological chemistry, 1950, Volume: 185, Issue:1 Topics: 2-Aminopurine; Guanine; Nucleic Acids; Purines	1950
Combination of nitrogen dioxide radicals with 8-oxo-7,8-dihydroguanine and guanine radicals in DNA: oxidation and nitration end-products. Journal of the American Chemical Society, 2005, Feb-23, Volume: 127, Issue:7 Topics: 2-Aminopurine; Chromatography, High Pressure Liquid; DNA; Free Radicals; Guanine; Isotope Labeling; Kinetics; Nitrogen Dioxide; Oligonucleotides; Oxidation-Reduction; Oxygen Isotopes; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2005
Drugs for non-HIV viral infections. Treatment guidelines from the Medical Letter, 2005, Volume: 3, Issue:32 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cytomegalovirus Infections; Drug Resistance, Viral; Famciclovir; Guanine; Hepatitis B; Hepatitis C; Herpes Simplex; Herpes Zoster; Humans; Influenza, Human; Valacyclovir; Valine; Virus Diseases	2005
Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal. Nucleic acids research, 2005, Volume: 33, Issue:14 Topics: 2-Aminopurine; Crystallography, X-Ray; DNA; Fluorescent Dyes; G-Quadruplexes; Guanine; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Potassium; Sodium; Solutions; Telomere; Ultracentrifugation	2005
Unrestricted accessibility of short oligonucleotides to RNA. RNA (New York, N.Y.), 2005, Volume: 11, Issue:9 Topics: 2-Aminopurine; Base Pairing; Guanine; Hypoxanthine; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; RNA; RNA Probes; Temperature; Thiouracil	2005
Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain. Journal of molecular biology, 2006, Jun-09, Volume: 359, Issue:3 Topics: 2-Aminopurine; 5' Untranslated Regions; Adenine; Aptamers, Nucleotide; Guanine; Ligands; Models, Molecular; Mutation; Nucleic Acid Conformation; Purines; Pyrimidines; Regulatory Sequences, Ribonucleic Acid; RNA, Bacterial; Thermodynamics	2006
Improved industrial syntheses of penciclovir and famciclovir using N2-acetyl-7-benzylguanine and a cyclic side chain precursor. Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:4-6 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Famciclovir; Guanine; Molecular Structure; Prodrugs	2006
Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase. The Journal of biological chemistry, 2006, Nov-24, Volume: 281, Issue:47 Topics: 2-Aminopurine; Base Sequence; DNA; DNA Topoisomerases, Type I; Guanine; Indoles; Models, Molecular; Molecular Sequence Data; Oligonucleotides; Protein Binding; Recombinant Proteins; Toluene; Tyrosine; Vaccinia virus	2006
Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine. Antiviral chemistry & chemotherapy, 2006, Volume: 17, Issue:2 Topics: 2-Aminopurine; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Guanine; Herpesvirus 1, Human; Humans; Magnetic Resonance Spectroscopy; Organophosphonates; Spectrometry, Mass, Electrospray Ionization; Viral Plaque Assay	2006
Kinetic conformational analysis of human 8-oxoguanine-DNA glycosylase. The Journal of biological chemistry, 2007, Jan-12, Volume: 282, Issue:2 Topics: 2-Aminopurine; Catalysis; Cytosine; DNA Glycosylases; DNA Repair; Enzyme Activation; Guanine; Guanosine; Humans; Kinetics; Ligands; Nucleotides; Protein Conformation; Reactive Oxygen Species; Substrate Specificity	2007
Ligand recognition determinants of guanine riboswitches. Nucleic acids research, 2007, Volume: 35, Issue:16 Topics: 2-Aminopurine; Bacillus subtilis; Base Sequence; Consensus Sequence; Fluorescent Dyes; Gene Expression Regulation, Bacterial; Guanine; Ligands; Molecular Sequence Data; Nucleic Acid Conformation; Regulatory Sequences, Ribonucleic Acid; RNA, Bacterial; RNA, Messenger; Transcription, Genetic; Untranslated Regions	2007
2,6-Diaminopurine, a precursor of nucleic acid guanine. The Journal of biological chemistry, 1948, Volume: 176, Issue:3 Topics: 2-Aminopurine; Guanine; Nucleic Acids	1948
An ab initio study of substituent effects on the excited states of purine derivatives. The journal of physical chemistry. A, 2008, Dec-04, Volume: 112, Issue:48 Topics: 2-Aminopurine; Adenine; Electrons; Gases; Guanine; Hypoxanthine; Isomerism; Purines; Quantum Theory; Xanthine	2008
Impact of ketone and amino on the inner shell of guanine. Journal of synchrotron radiation, 2009, Volume: 16, Issue:Pt 4 Topics: 2-Aminopurine; DNA; Guanine; Hypoxanthine; Models, Chemical; Models, Molecular; Photochemical Processes; Purines; Quantum Theory; Structure-Activity Relationship; Synchrotrons	2009
Pharmacokinetics of penciclovir after oral administration of its prodrug famciclovir to horses. The Journal of veterinary medical science, 2010, Volume: 72, Issue:3 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Famciclovir; Guanine; Half-Life; Herpesviridae Infections; Herpesvirus 1, Equid; Horse Diseases; Horses	2010
Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation. The Journal of organic chemistry, 2010, Mar-05, Volume: 75, Issue:5 Topics: 2-Aminopurine; Adenosine; Glycosylation; Guanine; Guanosine; Molecular Structure; Nucleosides; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship	2010
Heterogeneity and dynamics of the ligand recognition mode in purine-sensing riboswitches. Biochemistry, 2010, May-04, Volume: 49, Issue:17 Topics: 2-Aminopurine; Adenine; Aptamers, Nucleotide; Base Pairing; Base Sequence; Binding Sites; Fluorescence Polarization; Guanine; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Catalytic; Spectrometry, Fluorescence; Thermodynamics	2010
Kinetics of charge separation in poly(A)-poly(T) DNA hairpins. The journal of physical chemistry. B, 2010, May-20, Volume: 114, Issue:19 Topics: 2-Aminopurine; Adenosine; Base Pairing; DNA; Guanine; Imides; Kinetics; Naphthalenes; Phenothiazines; Polymers; Thymidine	2010
Self-dissociative primers for nucleic acid amplification and detection based on DNA quadruplexes with intrinsic fluorescence. Analytical biochemistry, 2011, Feb-01, Volume: 409, Issue:1 Topics: 2-Aminopurine; DNA; DNA Primers; G-Quadruplexes; Guanine; Nucleic Acid Amplification Techniques; Spectrometry, Fluorescence; Temperature	2011
Fluorescence properties of 8-(2-pyridyl)guanine "2PyG" as compared to 2-aminopurine in DNA. Chembiochem : a European journal of chemical biology, 2011, Sep-05, Volume: 12, Issue:13 Topics: 2-Aminopurine; Circular Dichroism; DNA; Fluorescence; G-Quadruplexes; Guanine; Guanosine Monophosphate; Humans; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Quantum Theory; Thermodynamics	2011
Ultrafast site-specific fluorescence quenching of 2-aminopurine in a DNA hairpin studied by femtosecond down-conversion. The journal of physical chemistry. A, 2012, Mar-22, Volume: 116, Issue:11 Topics: 2-Aminopurine; DNA, Viral; Fluorescence; Guanine; HIV-1; Humans; Inverted Repeat Sequences; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Signal-To-Noise Ratio; Solutions; Spectrometry, Fluorescence; Thermodynamics; Time Factors	2012
Proton-coupled hole hopping in nucleosomal and free DNA initiated by site-specific hole injection. Physical chemistry chemical physics : PCCP, 2012, May-28, Volume: 14, Issue:20 Topics: 2-Aminopurine; Base Sequence; DNA; DNA Damage; Guanine; Histones; Hydroxyl Radical; Models, Molecular; Molecular Sequence Data; Nucleosomes; Oxidation-Reduction; Protein Multimerization; Protein Refolding; Protons; Recombinant Proteins	2012
Pharmacokinetics of penciclovir in healthy cats following oral administration of famciclovir or intravenous infusion of penciclovir. American journal of veterinary research, 2012, Volume: 73, Issue:7 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Biological Availability; Cats; Cross-Over Studies; Famciclovir; Female; Guanine; Half-Life; Male; Prodrugs	2012
Estimates of the pharmacokinetics of famciclovir and its active metabolite penciclovir in young Asian elephants (Elephas maximus). American journal of veterinary research, 2012, Volume: 73, Issue:12 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Rectal; Animals; Antiviral Agents; Area Under Curve; Chromatography, Liquid; Cross-Over Studies; Elephants; Famciclovir; Female; Guanine; Half-Life; Male; Mass Spectrometry	2012
Isothermal quadruplex priming amplification for DNA-based diagnostics. Biophysical chemistry, 2013, Volume: 171 Topics: 2-Aminopurine; Base Sequence; DNA; DNA Primers; Fluorescent Dyes; G-Quadruplexes; Guanine; Nucleic Acid Amplification Techniques; Spectrometry, Fluorescence; Temperature; Templates, Genetic; Thermodynamics; Xanthopterin	2013
Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:7 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Aged; Aged, 80 and over; Antiviral Agents; Aqueous Humor; Famciclovir; Female; Guanine; Humans; Male; Middle Aged; Models, Statistical; Plasma	2013
Exciplexes and conical intersections lead to fluorescence quenching in π-stacked dimers of 2-aminopurine with natural purine nucleobases. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2013, Volume: 12, Issue:8 Topics: 2-Aminopurine; Adenine; Dimerization; Fluorescence; Guanine; Models, Molecular	2013
In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites. Veterinary ophthalmology, 2014, Volume: 17, Issue:4 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Cats; Cell Line; Dose-Response Relationship, Drug; Famciclovir; Guanine; Herpesviridae; Inhibitory Concentration 50; Viral Plaque Assay	2014
Monitoring translocation of multisubunit RNA polymerase along the DNA with fluorescent base analogues. Methods in molecular biology (Clifton, N.J.), 2015, Volume: 1276 Topics: 2-Aminopurine; Adenine; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Fluorescence; Guanine; Molecular Biology; Molecular Structure; Oligonucleotides; Spectrometry, Fluorescence; Transcription, Genetic; Xanthopterin	2015
Lesion search and recognition by thymine DNA glycosylase revealed by single molecule imaging. Nucleic acids research, 2015, Mar-11, Volume: 43, Issue:5 Topics: 2-Aminopurine; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Guanine; Humans; Microscopy, Atomic Force; Mutation; Nucleic Acid Conformation; Substrate Specificity; Thymine DNA Glycosylase	2015
Effects of four nucleoside analogues used as antiviral agents on rat Sertoli cells (SerW3) in vitro. Archives of toxicology, 2016, Volume: 90, Issue:8 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Biomarkers; Blotting, Western; Cadherins; Cell Culture Techniques; Cell Line; Connexin 43; Dose-Response Relationship, Drug; Famciclovir; Ganciclovir; Guanine; Male; Microscopy, Fluorescence; Nerve Tissue Proteins; Rats; Sertoli Cells; Vimentin	2016
Effect of nucleobase change on cytosine deamination through DNA photo-cross-linking reaction via 3-cyanovinylcarbazole nucleoside. Molecular bioSystems, 2017, Jun-01, Volume: 13, Issue:6 Topics: 2-Aminopurine; Base Pairing; Cytosine; Deamination; DNA; Guanine; Hydrogen Bonding; Indoles; Molecular Structure; Mutagenesis, Site-Directed; Nucleosides; Oligodeoxyribonucleotides; Purine Nucleosides; Ribonucleosides	2017
Structure-Activity Relationships of Acyclic Selenopurine Nucleosides as Antiviral Agents. Molecules (Basel, Switzerland), 2017, Jul-12, Volume: 22, Issue:7 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cytomegalovirus; Guanine; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Nucleosides; Organoselenium Compounds; Prodrugs; Purines; Simplexvirus; Structure-Activity Relationship	2017
Ultrafast structural dynamics of photoexcited adenine. Physical chemistry chemical physics : PCCP, 2017, Aug-02, Volume: 19, Issue:30 Topics: 2-Aminopurine; Adenine; Guanine; Quantum Theory; Spectrum Analysis, Raman; Ultraviolet Rays	2017
Purine-Derived Nitroxides for Noncovalent Spin-Labeling of Abasic Sites in Duplex Nucleic Acids. Chemistry (Weinheim an der Bergstrasse, Germany), 2018, Mar-15, Volume: 24, Issue:16 Topics: 2-Aminopurine; Adenine; Cyclic N-Oxides; Cytosine; DNA; Guanine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acids; Purines; RNA; Spin Labels; Thymine	2018
Proton Transfer and Tautomerism in 2-Aminopurine-Thymine and Pyrrolocytosine-Guanine Base Pairs. Biochemistry, 2018, 07-31, Volume: 57, Issue:30 Topics: 2-Aminopurine; Base Pairing; Cytosine; Electrons; Guanine; Models, Molecular; Protons; Pyrroles; Quantum Theory; Stereoisomerism; Thermodynamics; Thymine	2018
Base-Pairing Properties of Double-Headed Nucleotides. Chemistry (Weinheim an der Bergstrasse, Germany), 2019, May-28, Volume: 25, Issue:30 Topics: 2-Aminopurine; Adenine; Base Pair Mismatch; Base Pairing; Cytosine; DNA; Guanine; Hypoxanthine; Models, Molecular; Nucleic Acid Conformation; Nucleotides; Thymine	2019
Effect of mutations on binding of ligands to guanine riboswitch probed by free energy perturbation and molecular dynamics simulations. Nucleic acids research, 2019, 07-26, Volume: 47, Issue:13 Topics: 2-Aminopurine; Bacillus subtilis; Bacterial Proteins; Gene Expression Regulation, Bacterial; Guanine; Hypoxanthine; Ligands; Membrane Transport Proteins; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Point Mutation; Riboswitch; Structure-Activity Relationship; Thermodynamics	2019
Protein unties the pseudoknot: S1-mediated unfolding of RNA higher order structure. Nucleic acids research, 2020, 02-28, Volume: 48, Issue:4 Topics: 2-Aminopurine; Binding Sites; Escherichia coli; Guanine; Ligands; Nucleic Acid Conformation; Pyrimidinones; Pyrroles; Ribosomal Proteins; Ribosomes; Riboswitch; RNA; RNA Folding; Single Molecule Imaging	2020