Page last updated: 2024-08-21

2-aminopurine and brl 42359

2-aminopurine has been researched along with brl 42359 in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (80.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Allen, GD; Brown, TA; Filer, CW; Fowles, SE; Hollis, FJ; Mort, EE; Ramji, JV	1
Chenery, RJ; Clarke, SE; Harrell, AW	1
Fairless, AJ; Fowles, S; Georgiou, P; Laroche, J; Pratt, SK; Prince, W; Pue, MA	1
Beedham, C; Clarke, SE; Rashidi, MR; Smith, JA	1
Contreras, MT; Groth, AD; Kado-Fong, HK; Maggs, DJ; Nguyen, KQ; Thomasy, SM	1

Trials

1 trial(s) available for 2-aminopurine and brl 42359

Article	Year
Linear pharmacokinetics of penciclovir following administration of single oral doses of famciclovir 125, 250, 500 and 750 mg to healthy volunteers. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:1 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Famciclovir; Guanine; Half-Life; Humans; Male; Middle Aged; Prodrugs; Single-Blind Method; Spectrophotometry, Ultraviolet	1994

Article

Year

Linear pharmacokinetics of penciclovir following administration of single oral doses of famciclovir 125, 250, 500 and 750 mg to healthy volunteers.

The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:1

Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Famciclovir; Guanine; Half-Life; Humans; Male; Middle Aged; Prodrugs; Single-Blind Method; Spectrophotometry, Ultraviolet

1994

Other Studies

4 other study(ies) available for 2-aminopurine and brl 42359

Article	Year
Metabolic and pharmacokinetic studies following oral administration of famciclovir to the rat and dog. Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:5 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Biotransformation; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Famciclovir; Feces; Guanine; Male; Mass Spectrometry; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrophotometry, Ultraviolet	1995
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver. Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:2 Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Antiviral Agents; Benzaldehydes; Cytosol; Famciclovir; Guanine; Humans; Kinetics; Liver; Oxidation-Reduction; Prodrugs; Vitamin K; Xanthine Oxidase	1995
In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver. Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:7 Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Antiviral Agents; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Famciclovir; Female; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Liver; Male; Oxidation-Reduction; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrophotometry, Ultraviolet; Xanthine Oxidase	1997
In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites. Veterinary ophthalmology, 2014, Volume: 17, Issue:4 Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Cats; Cell Line; Dose-Response Relationship, Drug; Famciclovir; Guanine; Herpesviridae; Inhibitory Concentration 50; Viral Plaque Assay	2014