2-aminopurine has been researched along with allopurinol in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brereton, IM; de Jersey, J; Guddat, LW; Jones, MK; Keough, DT; Ng, AL; Skinner-Adams, T | 1 |
| Chen, ST; Choong, KF; Hsieh, JF; Wu, SH; Yang, YL | 1 |
| Chaudhary, D; Chauhan, V; Dhaked, RK; Pathak, U; Saxena, N | 1 |
| Czochralska, B; Johansson, NG; Kusmierek, JT; Shugar, D | 1 |
| Chenery, RJ; Clarke, SE; Harrell, AW | 1 |
| Fowles, SE; Laroche, J; Pratt, SK; Prince, WT | 1 |
| Maung, M; Slomka, MJ; Tsiquaye, KN | 1 |
| Beedham, C; Clarke, SE; Rashidi, MR; Smith, JA | 1 |
| Boudinot, FD; Chu, CK; Manouilov, KK; Manouilova, LS; Schinazi, RF | 1 |
| Chen, X; Drach, JC; Kern, ER; Wang, R; Zemlicka, J | 1 |
| BERGMANN, F; KWIETNY, H; LEVIN, G | 1 |
11 other study(ies) available for 2-aminopurine and allopurinol
| Article | Year |
|---|---|
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.
Topics: Animals; Antimalarials; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Pentosyltransferases; Plasmodium falciparum; Purines; Structure-Activity Relationship | 2006 |
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Leaves; Purines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Triticum; Xanthine Oxidase | 2007 |
In Silico Discovery and Validation of Amide Based Small Molecule Targeting the Enzymatic Site of Shiga Toxin.
Topics: Amides; Animals; Cells, Cultured; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Discovery; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Shiga Toxin; Small Molecule Libraries; Structure-Activity Relationship; Vero Cells | 2016 |
Preparative electrochemical reduction of 2-amino-6-chloropurine and synthesis of 6-deoxyacyclovir, a fluorescent substrate of xanthine oxidase and a prodrug of acyclovir.
Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Electrolysis; Guinea Pigs; Herpes Simplex; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Polarography; Prodrugs; Simplexvirus; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Viral Plaque Assay; Xanthine Oxidase | 1987 |
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver.
Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Antiviral Agents; Benzaldehydes; Cytosol; Famciclovir; Guanine; Humans; Kinetics; Liver; Oxidation-Reduction; Prodrugs; Vitamin K; Xanthine Oxidase | 1995 |
Lack of a pharmacokinetic interaction between oral famciclovir and allopurinol in healthy volunteers.
Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Adult; Allopurinol; Antiviral Agents; Drug Interactions; Famciclovir; Guanine; Half-Life; Humans; Male; Middle Aged; Oxypurinol | 1994 |
Oral famciclovir against duck hepatitis B virus replication in hepatic and nonhepatic tissues of ducklings infected in ovo.
Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Animals, Newborn; Antiviral Agents; Biotransformation; Disease Models, Animal; DNA, Viral; Ducks; Eggs; Famciclovir; Guanine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Kidney; Liver; Organ Specificity; Pancreas; Poultry Diseases; Prodrugs; Spleen; Viremia; Virus Replication; Xanthine Oxidase | 1994 |
In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver.
Topics: 2-Aminopurine; Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Antiviral Agents; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Famciclovir; Female; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Liver; Male; Oxidation-Reduction; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrophotometry, Ultraviolet; Xanthine Oxidase | 1997 |
Biotransformation and pharmacokinetics of prodrug 9-(beta-D-1,3-dioxolan-4-yl)-2-aminopurine and its antiviral metabolite 9-(beta-D-1,3-dioxolan-4-yl)guanine in mice.
Topics: 2-Aminopurine; Administration, Oral; Allopurinol; Animals; Biotransformation; Brain Chemistry; Dioxolanes; Drug Interactions; Female; Guanine; Guanosine; Injections, Intravenous; Liver; Mice; Prodrugs; Purines; Xanthine Oxidase | 1997 |
Synthesis and biological activity of 2-aminopurine methylenecyclopropane analogues of nucleosides.
Topics: 2-Aminopurine; Alkylation; Antiviral Agents; Chromatography, Gel; Cyclopropanes; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Nucleosides; Prodrugs; Spectrophotometry, Ultraviolet; Stereoisomerism; Xanthine Oxidase | 2003 |
The oxidation of 2-aminopurine by mammalian xanthine oxidase.
Topics: 2-Aminopurine; Animals; Biochemical Phenomena; Mammals; Oxidation-Reduction; Oxidoreductases; Purines; Xanthine Oxidase | 1958 |