2-aminomethyl-4-t-butyl-6-iodophenol has been researched along with furosemide in 3 studies
| Studies (2-aminomethyl-4-t-butyl-6-iodophenol) | Trials (2-aminomethyl-4-t-butyl-6-iodophenol) | Recent Studies (post-2010) (2-aminomethyl-4-t-butyl-6-iodophenol) | Studies (furosemide) | Trials (furosemide) | Recent Studies (post-2010) (furosemide) |
|---|---|---|---|---|---|
| 41 | 0 | 1 | 13,631 | 1,358 | 2,486 |
| Protein | Taxonomy | 2-aminomethyl-4-t-butyl-6-iodophenol (IC50) | furosemide (IC50) |
|---|---|---|---|
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Homo sapiens (human) | 3.76 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Mus musculus (house mouse) | 3.76 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cragoe, EJ; Ludden, CT; Russo, HF; Smith, RL; Stokker, GE; Sweet, CS; Watson, LS | 1 |
| Johnston, PA; Kau, ST | 1 |
| Johnston, PA; Kau, ST; Leszczynska, K; Yochim, C | 1 |
3 other study(ies) available for 2-aminomethyl-4-t-butyl-6-iodophenol and furosemide
| Article | Year |
|---|---|
2-(Aminomethyl)phenols, a new class of saluretic agents. 2. Synthesis and pharmacological properties of the 5-aza isostere of 2-(aminomethyl)-4-(1,1-dimethylethyl)-6-iodophenol.
Topics: Animals; Blood Pressure; Chemical Phenomena; Chemistry; Diuretics; Dogs; Electrolytes; Hypertension; Iodopyridones; Rats | 1981 |
Micropuncture evaluation of the site of action of 2-aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride (MK447) in the rat kidney.
Topics: Absorption; Animals; Butylated Hydroxytoluene; Diuretics; Furosemide; Kidney; Male; Perfusion; Potassium; Punctures; Rats; Rats, Inbred Strains; Sodium | 1991 |
Effect of route of administration on the relative efficacy and potency of 2-aminoethyl-4-(1,1-dimethylethyl)-6-iodophenol HCl (MK447) and furosemide.
Topics: Administration, Oral; Animals; Butylated Hydroxytoluene; Diuretics; Dogs; Female; Furosemide; Infusions, Intravenous; Injections, Intravenous; Kidney; Male; Rats; Rats, Inbred Strains; Species Specificity | 1990 |