Page last updated: 2024-09-03

2-aminobicyclo(2,2,1)heptane-2-carboxylic acid and tolbutamide

2-aminobicyclo(2,2,1)heptane-2-carboxylic acid has been researched along with tolbutamide in 2 studies

Compound Research Comparison

Studies
(2-aminobicyclo(2,2,1)heptane-2-carboxylic acid)
Trials
(2-aminobicyclo(2,2,1)heptane-2-carboxylic acid)
Recent Studies (post-2010)
(2-aminobicyclo(2,2,1)heptane-2-carboxylic acid)
Studies
(tolbutamide)
Trials
(tolbutamide)
Recent Studies (post-2010) (tolbutamide)
1660345,368238265

Protein Interaction Comparison

ProteinTaxonomy2-aminobicyclo(2,2,1)heptane-2-carboxylic acid (IC50)tolbutamide (IC50)
Cytochrome P450 2C9 Homo sapiens (human)0.392

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christensen, HN; Tager, HS1
Bertrand, G; Henquin, JC; Ishiyama, N; Nenquin, M; Ravier, MA1

Other Studies

2 other study(ies) available for 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid and tolbutamide

ArticleYear
Hypoglycemic action of 2-aminonorbornane-2-carboxylic acid in the rat.
    Biochemical and biophysical research communications, 1971, Jul-02, Volume: 44, Issue:1

    Topics: Amino Acids; Amino Acids, Cyclic; Animals; Binding Sites; Blood Glucose; Drug Synergism; Hypoglycemia; Insulin; Insulin Secretion; Kinetics; Leucine; Male; Rats; Stereoisomerism; Structure-Activity Relationship; Terpenes; Tolbutamide

1971
The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related.
    The Journal of biological chemistry, 2002, Sep-06, Volume: 277, Issue:36

    Topics: Allosteric Site; Amino Acids, Cyclic; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Exocytosis; Female; Glucose; Glutamic Acid; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Male; Mice; Pancreas; Potassium; Potassium Chloride; Protein Binding; Rats; Rats, Wistar; Time Factors; Tolbutamide

2002