2-aminobicyclo(2,2,1)heptane-2-carboxylic acid has been researched along with sirolimus in 3 studies
| Studies (2-aminobicyclo(2,2,1)heptane-2-carboxylic acid) | Trials (2-aminobicyclo(2,2,1)heptane-2-carboxylic acid) | Recent Studies (post-2010) (2-aminobicyclo(2,2,1)heptane-2-carboxylic acid) | Studies (sirolimus) | Trials (sirolimus) | Recent Studies (post-2010) (sirolimus) |
|---|---|---|---|---|---|
| 166 | 0 | 34 | 20,711 | 2,368 | 11,516 |
| Protein | Taxonomy | 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid (IC50) | sirolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.25 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | 0.001 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 4 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0897 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.0042 | |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | 0.225 | |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | 0.225 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.9 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akaishi, R; Fujimura, S; Furuya, N; Kadowaki, M; Kanazawa, T; Taneike, I; Yoshizawa, F | 1 |
| Ishikawa, T; Kadota, Y; Kitaura, Y; Kondo, Y; Nakamura, K; Shimomura, Y; Xu, M; Zhen, H | 1 |
| Jihong, P; Lin, W; Rui, Z; Yu, Z | 1 |
3 other study(ies) available for 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid and sirolimus
| Article | Year |
|---|---|
Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Bacterial Toxins; Cell Membrane; Enzyme Inhibitors; Hemolysin Proteins; Hepatocytes; Insulin; Leucine; Male; Peptide Hydrolases; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2004 |
Regulation of the plasma amino acid profile by leucine via the system L amino acid transporter.
Topics: Amino Acid Transport System L; Amino Acids; Amino Acids, Cyclic; Animals; Dose-Response Relationship, Drug; Leucine; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Sirolimus; Time Factors; TOR Serine-Threonine Kinases | 2015 |
Fibroblast-like synoviocyte migration is enhanced by IL-17-mediated overexpression of L-type amino acid transporter 1 (LAT1) via the mTOR/4E-BP1 pathway.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Amino Acids, Cyclic; Arthritis, Rheumatoid; Cell Cycle Proteins; Cell Movement; Cells, Cultured; Female; Fibroblasts; Gene Expression; Gene Expression Regulation; Humans; Leucine; Middle Aged; Phosphoproteins; RNA, Small Interfering; Signal Transduction; Sirolimus; Synovial Membrane; Synoviocytes; TOR Serine-Threonine Kinases | 2018 |