Page last updated: 2024-09-03

2-aminobicyclo(2,2,1)heptane-2-carboxylic acid and gamma-aminobutyric acid

2-aminobicyclo(2,2,1)heptane-2-carboxylic acid has been researched along with gamma-aminobutyric acid in 4 studies

Compound Research Comparison

Studies
(2-aminobicyclo(2,2,1)heptane-2-carboxylic acid)
Trials
(2-aminobicyclo(2,2,1)heptane-2-carboxylic acid)
Recent Studies (post-2010)
(2-aminobicyclo(2,2,1)heptane-2-carboxylic acid)
Studies
(gamma-aminobutyric acid)
Trials
(gamma-aminobutyric acid)
Recent Studies (post-2010) (gamma-aminobutyric acid)
16603440,2151,4239,631

Protein Interaction Comparison

ProteinTaxonomy2-aminobicyclo(2,2,1)heptane-2-carboxylic acid (IC50)gamma-aminobutyric acid (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 2Rattus norvegicus (Norway rat)0.0292
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0332
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0323
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)2.152
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0333
Sodium- and chloride-dependent GABA transporter 1Homo sapiens (human)5.2623
Sodium- and chloride-dependent taurine transporterHomo sapiens (human)354
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)2.51
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent GABA transporter 1Mus musculus (house mouse)6.349
Sodium- and chloride-dependent GABA transporter 2Mus musculus (house mouse)7.0795
Sodium- and chloride-dependent GABA transporter 3Mus musculus (house mouse)8.1283
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent betaine transporterHomo sapiens (human)6.4082
Sodium- and chloride-dependent GABA transporter 3Homo sapiens (human)3.9953
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0333
GABA theta subunitRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 1Rattus norvegicus (Norway rat)0.0292

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, JK; Eisenach, JC; Pan, HL1
Al-Sarraf, H1
Brawek, B; Feuerstein, TJ; Löffler, M; Weyerbrock, A1
Frølund, S; Garmer, M; Holm, R; Kreilgaard, M; Larsen, MS; Nielsen, CU; Nøhr, MK1

Other Studies

4 other study(ies) available for 2-aminobicyclo(2,2,1)heptane-2-carboxylic acid and gamma-aminobutyric acid

ArticleYear
Antiallodynic effect of intrathecal gabapentin and its interaction with clonidine in a rat model of postoperative pain.
    Anesthesiology, 2000, Volume: 92, Issue:4

    Topics: Acetates; Adrenergic alpha-Agonists; Amines; Amino Acids; Amino Acids, Cyclic; Analgesics; Animals; Behavior, Animal; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Reflex

2000
Transport of 14C-gamma-aminobutyric acid into brain, cerebrospinal fluid and choroid plexus in neonatal and adult rats.
    Brain research. Developmental brain research, 2002, Dec-15, Volume: 139, Issue:2

    Topics: Aging; Amino Acids, Cyclic; Animals; Animals, Newborn; beta-Alanine; Biological Transport, Active; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cerebrospinal Fluid; Choroid Plexus; Female; gamma-Aminobutyric Acid; Male; Mannitol; Perfusion; Rats; Time Factors

2002
Effects of gabapentin and pregabalin on K+-evoked 3H-GABA and 3H-glutamate release from human neocortical synaptosomes.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:4

    Topics: Adolescent; Adult; Aged; Amines; Amino Acids, Cyclic; Anticonvulsants; Aspartic Acid; Calcium Channel Blockers; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Exocytosis; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Infant; Isoleucine; Male; Middle Aged; Neocortex; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Potassium; Pregabalin; Synaptosomes; Tacrolimus; Young Adult

2009
In vivo and in vitro evaluations of intestinal gabapentin absorption: effect of dose and inhibitors on carrier-mediated transport.
    Pharmaceutical research, 2015, Volume: 32, Issue:3

    Topics: Administration, Oral; Amines; Amino Acids, Cyclic; Animals; Caco-2 Cells; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Male; Membrane Transport Modulators; Membrane Transport Proteins; Models, Biological; Rats, Sprague-Dawley

2015