2-aminoadipic acid has been researched along with lysine in 119 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (36.13) | 18.7374 |
| 1990's | 17 (14.29) | 18.2507 |
| 2000's | 27 (22.69) | 29.6817 |
| 2010's | 27 (22.69) | 24.3611 |
| 2020's | 5 (4.20) | 2.80 |
| Authors | Studies |
|---|---|
| Stahmann, MA | 1 |
| Mechanic, GL | 1 |
| Demain, AL; Friedrich, CG | 2 |
| Casey, RE; MacKenzie, SL; Mendelson, IS; Philp, M; Zaleski, WA | 1 |
| Brandt, NJ; Christensen, E; Gregersen, N; Grøn, IH; Rasmussen, K | 1 |
| Bhattacharjee, JK; Kinzel, JJ | 1 |
| Ranta, H | 1 |
| Friede, JD; Henderson, LM | 1 |
| Spencer, AK; Stahmann, MA | 1 |
| Boulanger, P; Mizon, J | 1 |
| Boon, B; Roelants, P; Troonen, H | 1 |
| Fournier, P; Gaillardin, C; Heslot, H; Sylvestre, G | 1 |
| Filipek, J; Kuryłowicz, W; Kurzatkowski, JD; Kurzatkowski, W; Solecka, J | 1 |
| Brakhage, AA; Turner, G | 1 |
| Bode, R; Hammer, T | 1 |
| Divry, P; Mathieu, M; Vianey-Liaud, C | 1 |
| Bhattacharjee, JK; Garrad, RC; Winston, MK; Ye, ZH | 1 |
| Madduri, K; Stuttard, C; Vining, LC | 1 |
| Affenzeller, K; Hönlinger, C; Jaklitsch, WM; Kubicek, CP | 1 |
| Drescher, DG; Drescher, MJ | 1 |
| Chang, YF; Myslinski, NR | 1 |
| Alvarez, E; López-Nieto, MJ; Martín, JF; Ramos, FR; Revilla, G | 1 |
| Guarneri, P; Guarneri, R; Piccoli, F; Ponte, F | 1 |
| Dubois, E; Piérard, A; Ramos, F | 1 |
| Hampel, WA; Hönlinger, C; Kubicek, CP; Röhr, M | 1 |
| Bhattacharjee, JK; Winston, MK | 1 |
| Bhattacharjee, JK; Ye, ZH | 1 |
| Sherman, F; Zaret, KS | 1 |
| Bhattacharjee, JK | 1 |
| Hartline, RA | 1 |
| Beemer, FA; Duran, M; Janssen, B; Wadman, SK; Wendel, U | 1 |
| Brown, RR; Fischer, MH | 1 |
| Hendlin, D; Inamine, E; Kern, BA | 1 |
| Crombie, G; Faris, B; Franzblau, C; Snider, R | 1 |
| Chang, YF | 1 |
| Arneson, DW; Tipton, RE; Ward, JC | 1 |
| Dubois, E; Feller, A; Piérard, A; Ramos, F | 3 |
| Alvarez, E; Esmahan, C; Martin, JF; Montenegro, E | 1 |
| Ghali, D; Kubicek, CP; Kubicek-Pranz, EM; Lendenfeld, T; Wolschek, M | 1 |
| Perry, D; Sim, KL | 1 |
| de La Fuente, JL; Liras, P; Martín, JF; Rumbero, A | 1 |
| Ajami, AM; Al-Amiri, HA; Atkinson, A; Basile, A; Beaumier, L; El-Khoury, AE; Selvaraj, A; Wang, SY; Wong, S; Young, VR | 1 |
| Hoshino, T; Kosuge, T | 1 |
| Kobashi, N; Nishiyama, M; Tanokura, M | 1 |
| Ehmann, DE; Gehring, AM; Walsh, CT | 1 |
| Hoshino, T; Kobashi, N; Kosuge, T; Nishida, H; Nishiyama, M; Yamane, H | 1 |
| Bañuelos, O; Casqueiro, J; Gutiérrez, S; Martín, JF | 1 |
| Akagawa, M; Suyama, K | 1 |
| Galili, G; Tang, G; Zhu, X | 1 |
| Nishida, H; Nishiyama, M | 1 |
| Johansson, E; Lindqvist, Y; Schneider, G; Steffens, JJ | 1 |
| Kobashi, N; Miyazaki, J; Nishiyama, M; Yamane, H | 1 |
| Dubois, E; El Alami, M; Feller, A; Piérard, A | 1 |
| Akagawa, M; Sasaki, T; Suyama, K | 1 |
| Gotoh, K; Kuramitsu, S; Matsuura, T; Nishiyama, M; Sakai, H; Sekine, Si; Shirouzu, M; Terada, T; Vassylyev, DG; Vassylyeva, MN; Yokoyama, S | 1 |
| VOGEL, HJ; YURA, T | 1 |
| SAGISAKA, S; SHIMURA, K | 3 |
| DEMAIN, AL; NEWKIRK, JF | 1 |
| BROQUIST, HP; KUO, MH; SAUNDERS, PP | 1 |
| BROQUIST, HP; KUO, MH; SAUNDERS, P | 1 |
| Battaglia, FC; Meschia, G; Teng, C; Wilkening, RB; Wilkes, PT; Zhu, Y | 1 |
| Bañuelos, O; Casqueiro, J; Lamas-Maceiras, M; Martín de Valmaseda, E; Martín, JF; Naranjo, L; Ullán, RV | 1 |
| WINDSOR, E | 1 |
| Balogh, H; Kaminskyj, SG; Ma, G; Marko, M; Palmer, DR; Zhou, X | 1 |
| Nishiyama, M | 2 |
| Fascetti, A; Rucker, R; Sheets, A; Storms, D; Tchaparian, E | 1 |
| Campoy, S; Casqueiro, J; Martín, JF; Naranjo, L; Valmaseda, EM | 1 |
| Campoy, S; Casqueiro, J; Lamas-Maceiras, M; Martín, JF; Naranjo, L; Teijeira, F; Ullán, RV | 1 |
| Espinosa-Urgel, M; Fuhrer, T; Ramos, JL; Revelles, O; Sauer, U | 1 |
| Isobe, K; Matuura, A; Nagasawa, S; Sakaguchi, T; Tokuta, K; Wakao, N | 1 |
| He, M | 1 |
| Andi, B; Cook, PF; Qian, J; West, AH; Xu, H | 1 |
| Bauerly, KA; Cheung, CP; Fascetti, AJ; Hajizadeh, S; Harris, CB; Rucker, RB; Satre, MA; Storms, DH; Sun, MY; Tchaparian, E | 1 |
| Gómez, D; Lucas-Elío, P; Sanchez-Amat, A; Solano, F | 1 |
| Eisenreich, W; Fuchs, G; Huber, H; Hügler, M; Jahn, U | 1 |
| Isobe, K; Nagasawa, S | 1 |
| BORSOOK, H; DEASY, CL | 2 |
| DUNN, HJ; GEIGER, E | 1 |
| Monnier, VM; Sell, DR; Shen, W; Strauch, CM | 1 |
| Fujimura, T; Horie, A; Kono, H; Kuzuyama, T; Mineki, R; Nishiyama, C; Nishiyama, M; Saiki, A; Taka, H; Tomita, T | 1 |
| Fan, X; Giblin, FJ; Liu, X; Monnier, VM; Nemet, I; Qian, J; Strauch, C; Theves, M; Zhang, J | 1 |
| Isobe, K | 1 |
| Fukuda, N; Isobe, K; Nagasawa, S; Saitou, K | 1 |
| Hoffmann, GF; Koeller, DM; Kölker, S; Okun, JG; Opp, S; Sauer, SW | 1 |
| Almasi, JN; Bushnell, EA; Gauld, JW | 1 |
| Bok, LA; Emal, D; Houterman, S; Jakobs, C; Struys, EA; Willemsen, MA | 1 |
| Ceyhan, S; Clayton, PT; Footitt, EJ; Jakobs, C; Mills, PB; Struys, EA; Waters, PJ | 1 |
| Bok, LA; Cheng, B; Collet, JP; Connolly, M; Coughlin, CR; Das, AM; Gospe, SM; Hartmann, H; Jaggumantri, S; Jakobs, C; Mercimek-Mahmutoglu, S; Meyer, U; Plecko, BR; Sinclair, G; Stockler, S; Struys, E; van der Lee, JH; Van Hove, J; van Karnebeek, CD | 1 |
| Brock, M; Fazius, F; Gebhardt, P; Shelest, E | 1 |
| Albers, SV; Fujimura, T; Horie, A; Kosono, S; Kuramitsu, S; Kuzuyama, T; Lassak, K; Masui, R; Mineki, R; Nishida, H; Nishiyama, C; Nishiyama, M; Ouchi, T; Taka, H; Takahashi, K; Tomita, T; Yoshida, A | 1 |
| Araujo, ML; Cavallieri, AP; Leite, CA | 1 |
| Davidson, VL; Sanchez-Amat, A; Sehanobish, E; Shin, S | 1 |
| Bliss, JM; Gabriel, I; Kur, K; Laforce-Nesbitt, SS; Milewski, S; Pulickal, AS | 1 |
| Fujimura, T; Kuzuyama, T; Nishiyama, C; Nishiyama, M; Tomita, T; Yoshida, A | 1 |
| Fujimura, S; Kadowaki, M; Kobayashi, H; Kubota, M; Shibata, M; Watanabe, G | 1 |
| Biffoni, M; Cappellari, M; De Maria, R; Grande, S; Guidoni, L; Luciani, AM; Pallini, R; Palma, A; Ricci-Vitiani, L; Rosi, A; Runci, D; Viti, V | 1 |
| Chang, HC; Cheng, RP; Chiu, WC; Fang, CJ; Huang, SJ; Huang, SL; Kuo, HT; Li, JH; Liu, SL; Wang, WR; Yang, PA | 1 |
| Hoffmeister, D; Kalb, D; Lackner, G; Rappe, M | 1 |
| Chou, HT; Lu, CD; Madhuri Indurthi, S | 1 |
| Arruda, P; Eberlin, MN; Laranjeira, ÂB; MacKenzie, A; Marques, LA; Pena, IA; Yunes, JA | 1 |
| Al Teneiji, A; Bruun, TU; Cordeiro, D; Inbar-Feigenberg, M; Mercimek-Mahmutoglu, S; Patel, J; Struys, E; Weiss, S | 1 |
| Dai, S; Fang, X; Hsu, WW; Kurra, Y; Liu, WR; Tharp, JM; Vatansever, EC; Wang, X; Wang, ZA; Zeng, Y | 1 |
| Gates, KS; Henzl, MT; Korasick, DA; Laciak, AR; Luo, M; Ruddraraju, K; Tanner, JJ; Wyatt, JW | 1 |
| Brinckmann, J; Heinz, A; Karaman Mayack, B; Majovsky, P; Schmelzer, CEH; Schräder, CU; Sippl, W | 1 |
| Crowther, LM; Mathis, D; Plecko, B; Poms, M | 1 |
| Gong, P; Jiang, S; Jiang, Y; Li, H; Wang, J; Wu, M; Wu, Y; Xue, J; Yang, W; Yang, Z; Yuzyuk, T; Zhang, Y | 1 |
| Alonso-Gómez, A; Clish, CB; Corella, D; Dennis, C; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hu, FB; Lapetra, J; Li, J; Liang, L; Martínez-González, MA; Pierce, KA; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Huetos, A; Salas-Salvadó, J; Serra-Majem, L; Toledo, E | 1 |
| Hedtke, T; Heinz, A; Schmelzer, CEH | 1 |
| Bouchereau, J; Schiff, M | 1 |
| Matthews, DE | 1 |
| Andrade, MJ; Estévez, M; Padilla, P; Peña, FJ; Rodríguez, A | 1 |
| An, N; Li, X; Shen, X; Sun, X; Wang, J; Yuan, Q; Zhang, Y; Zhao, Y | 1 |
10 review(s) available for 2-aminoadipic acid and lysine
| Article | Year |
|---|---|
[Inborn errors of lysine metabolism].
Topics: 2-Aminoadipic Acid; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Glutarates; Humans; Infant; Infant, Newborn; Lysine; Male; Pipecolic Acids | 1991 |
alpha-Aminoadipate pathway for the biosynthesis of lysine in lower eukaryotes.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Chromosome Mapping; Cloning, Molecular; Feedback; Lysine; Molecular Biology; Mutation; Pipecolic Acids; Recombination, Genetic; Saccharomyces cerevisiae | 1985 |
[Novel lysine biosynthesis: a key to elucidate evolution of metabolic and biosynthetic pathways].
Topics: 2-Aminoadipic Acid; Alcohol Oxidoreductases; Catalysis; Evolution, Molecular; Lysine; Oxo-Acid-Lyases; Substrate Specificity; Thermus thermophilus | 2004 |
Pipecolic acid in microbes: biosynthetic routes and enzymes.
Topics: 2-Aminoadipic Acid; Bacteria; Lysine; Pipecolic Acids | 2006 |
The alpha-aminoadipate pathway for lysine biosynthesis in fungi.
Topics: 2-Aminoadipate Transaminase; 2-Aminoadipic Acid; Alcohol Oxidoreductases; Bacteria; Fungi; Hydro-Lyases; Lysine; Oxo-Acid-Lyases; Plants; Saccharopine Dehydrogenases | 2006 |
Enzymes responsible for metabolism of Nα-benzyloxycarbonyl-L-lysine in microorganisms.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Amino Acid Sequence; Aspergillus niger; Bacterial Proteins; Fungal Proteins; Lysine; Molecular Sequence Data; Molecular Structure; Rhodococcus; Sequence Alignment | 2010 |
[Regulatory mechanisms of novel lysine biosynthesis in thermophile].
Topics: 2-Aminoadipic Acid; 2-Isopropylmalate Synthase; Arginine; Bacterial Proteins; Carrier Proteins; Gene Expression Regulation, Enzymologic; Ketoglutaric Acids; Lysine; Oxo-Acid-Lyases; Thermus thermophilus | 2012 |
Unique molecular networks: Formation and role of elastin cross-links.
Topics: 2-Aminoadipic Acid; Aging; Animals; Blood Vessels; Connective Tissue Diseases; Elastic Tissue; Elastin; Humans; Ligaments; Lung; Lysine; Microfibrils; Oxidation-Reduction; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase; Skin | 2020 |
Inherited Disorders of Lysine Metabolism: A Review.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Arginine; Brain; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Carnitine; Epilepsy; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Lysine; Metabolic Diseases; Pyridoxal Phosphate; Pyridoxine | 2020 |
Review of Lysine Metabolism with a Focus on Humans.
Topics: 2-Aminoadipic Acid; Acetyl Coenzyme A; Ammonia; Animals; Bacteria; Body Weight; Deficiency Diseases; Diet; Gastrointestinal Microbiome; Humans; Lysine; Nitrogen; Nutritional Requirements; Nutritional Status; Proteins; Urea | 2020 |
109 other study(ies) available for 2-aminoadipic acid and lysine
| Article | Year |
|---|---|
Cross-linking of protein by peroxidase.
Topics: 2-Aminoadipic Acid; Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Molecular Weight; Peroxidases; Proteins | 1977 |
The qualitative and quantitative crosslink chemistry of collagen matrices.
Topics: 2-Aminoadipic Acid; Animals; Aorta; Bone and Bones; Calcium; Chemical Phenomena; Chemistry; Chickens; Collagen; Histidine; Humans; Hydroxylysine; Lysine; Macromolecular Substances; Osteogenesis Imperfecta; Phosphates; Protein-Lysine 6-Oxidase; Rickets; Vitamin D Deficiency | 1977 |
Uptake and metabolism of alpha-aminoadipic acid by Penicillium chrysogenum Wis 54-1255.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Carbon Dioxide; Cysteine; Hydrogen-Ion Concentration; Lysine; Penicillin G; Penicillium; Penicillium chrysogenum; Valine | 1978 |
Biochemical and clinical studies of a new case of alpha-aminoadipic aciduria.
Topics: 2-Aminoadipic Acid; Amino Acid Metabolism, Inborn Errors; Amino Acids, Dicarboxylic; Child; Female; Gas Chromatography-Mass Spectrometry; Humans; Lysine; Pyridoxine; Thiamine | 1978 |
Effects of lysine analogs on Penicillium chrysogenum.
Topics: 2-Aminoadipic Acid; Drug Antagonism; Lysine; Penicillins; Penicillium; Penicillium chrysogenum; Spores, Fungal; Stereoisomerism | 1977 |
Treatment of glutaryl-CoA dehydrogenase deficiency (glutaric aciduria). Experience with diet, riboflavin, and GABA analogue.
Topics: 2-Aminoadipic Acid; Amino Acid Metabolism, Inborn Errors; Aminobutyrates; Baclofen; Child; Diet Therapy; Dietary Proteins; Female; Glutarates; Humans; Lysine; Male; Oxidoreductases; Riboflavin; Tryptophan | 1979 |
Role of pipecolic acid in the biosynthesis of lysine in Rhodotorula glutinis.
Topics: 2-Aminoadipic Acid; Lysine; Mitosporic Fungi; Mutation; Pipecolic Acids; Rhodotorula; Saccharopine Dehydrogenases; Substrate Specificity | 1979 |
Age-related changes in collagen cross-linking. Changes in bovine dentine and periodontal ligament and description of a new type of non-reducible cross-link.
Topics: 2-Aminoadipic Acid; Age Factors; Animals; Cattle; Chemical Phenomena; Chemistry; Collagen; Dentin; Lysine; Peptides; Periodontal Ligament | 1978 |
Metabolism of 5-hydroxylysine in Pseudomonas fluorescens.
Topics: 2-Aminoadipic Acid; Glutarates; Hydroxylysine; Lysine; Pipecolic Acids; Pseudomonas fluorescens; Racemases and Epimerases; Stereoisomerism | 1976 |
Deamination of protein lysyl epsilon-amino groups by peroxidase in vitro.
Topics: 2-Aminoadipic Acid; Deamination; Lysine; Mass Spectrometry; Peroxidases; Proteins | 1977 |
[The fate of alpha and epsilon lysine amino groups in rat liver in vitro (author's transl)].
Topics: 2-Aminoadipic Acid; Animals; Electrophoresis, Paper; Glutamates; Liver; Lysine; Rats | 1976 |
RIT 2214, a new biosynthetic penicillin produced by a mutant of Cephalosporium acremonium.
Topics: 2-Aminoadipic Acid; Acremonium; Animals; Bacteria; Bacterial Infections; Carbocysteine; Cephalosporins; Chemical Phenomena; Chemistry; Drug Stability; Fermentation; Lactams; Lysine; Mice; Penicillins; Time Factors | 1976 |
Mutants of Saccharomycopsis lipolytica defective in lysine catabolism.
Topics: 2-Aminoadipic Acid; Ascomycota; Genetic Complementation Test; Genetic Linkage; Lysine; Mutation; Phenotype; Pipecolic Acids; Recombination, Genetic; Saccharomycopsis; Valerates | 1976 |
Reversion of L-lysine inhibition of penicillin G biosynthesis by 6-oxopiperidine-2-carboxylic acid in Penicillium chrysogenum PQ-96.
Topics: 2-Aminoadipic Acid; Lysine; Penicillin G; Penicillium chrysogenum; Pipecolic Acids | 1990 |
L-lysine repression of penicillin biosynthesis and the expression of penicillin biosynthesis genes acvA and ipnA in Aspergillus nidulans.
Topics: 2-Aminoadipic Acid; Aspergillus nidulans; Cloning, Molecular; Fermentation; Gene Expression Regulation, Fungal; Genes, Fungal; Lysine; Oxidoreductases; Penicillin V; Peptide Synthases | 1992 |
Enzymatic production of alpha-aminoadipate-delta-semialdehyde and related compounds by lysine epsilon-dehydrogenase from Candida albicans.
Topics: 2-Aminoadipic Acid; Amino Acid Oxidoreductases; Candida albicans; Culture Media; Hydrogen-Ion Concentration; Lysine; Temperature | 1992 |
Use of alpha-aminoadipate and lysine as sole nitrogen source by Schizosaccharomyces pombe and selected pathogenic fungi.
Topics: 2-Aminoadipic Acid; Lysine; Nitrogen; Saccharomyces cerevisiae; Schizosaccharomyces | 1991 |
Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Anti-Bacterial Agents; beta-Lactams; Cadaverine; Diamines; Lysine; Molecular Structure; Mutation; Species Specificity; Streptomyces | 1989 |
Lysine biosynthesis in Penicillium chrysogenum is regulated by feedback inhibition of alpha-aminoadipate reductase.
Topics: 2-Aminoadipic Acid; Aldehyde Oxidoreductases; Feedback; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Penicillium; Penicillium chrysogenum | 1989 |
Amino acids, including neurotransmitter candidates, in a hair cell-enriched fraction from the lateral line of Xenopus laevis.
Topics: 2-Aminoadipic Acid; Amino Acids; Animals; Ethanolamines; Female; Hair Cells, Auditory; Lysine; Male; Neurotransmitter Agents; Phosphatidylethanolamines; Phosphoserine; Xenopus laevis | 1987 |
Effects of L-lysine and its metabolites on pentylenetetrazol-induced seizures.
Topics: 2-Aminoadipic Acid; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Lysine; Male; Mice; Pentylenetetrazole; Pipecolic Acids; Piperidines; Seizures; Synaptic Transmission | 1985 |
Glucose represses formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine and isopenicillin N synthase but not penicillin acyltransferase in Penicillium chrysogenum.
Topics: 2-Aminoadipic Acid; Acyltransferases; Bacterial Proteins; Cysteine; Enzyme Repression; Enzymes; Glucose; Lysine; Oligopeptides; Oxidoreductases; Oxo-Acid-Lyases; Penicillin-Binding Proteins; Penicillium; Penicillium chrysogenum; Peptide Synthases; Saccharopine Dehydrogenases; Valine | 1986 |
L-[3H]lysine binding to rat retinal membrane: II. Effect of kainic acid, D,L-alpha-aminoadipic acid, iodoacetic acid, and modification by dark-exposure.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Animals; Brain; Darkness; Iodoacetates; Iodoacetic Acid; Kainic Acid; Kinetics; Lysine; Male; Rats; Retina; Visual Pathways | 1986 |
Control of enzyme synthesis in the lysine biosynthetic pathway of Saccharomyces cerevisiae. Evidence for a regulatory role of gene LYS14.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Cloning, Molecular; Enzyme Induction; Enzyme Repression; Gene Expression Regulation; Genes, Fungal; Genes, Regulator; Lysine; Saccharomyces cerevisiae; Saccharopine Dehydrogenases; Transcription, Genetic | 1988 |
Differential effects of general amino acid control of lysine biosynthesis on penicillin formation in strains of Penicillium chrysogenum.
Topics: 2-Aminoadipic Acid; Aldehyde Oxidoreductases; Amino Acids; Amitrole; Chromatography, High Pressure Liquid; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Penicillins; Penicillium; Penicillium chrysogenum | 1988 |
Biosynthetic and regulatory role of lys9 mutants of Saccharomyces cerevisiae.
Topics: 2-Aminoadipic Acid; Genes; Genes, Fungal; Genes, Mating Type, Fungal; Genes, Recessive; Genes, Regulator; Lysine; Mutation; Saccharomyces cerevisiae | 1987 |
Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe.
Topics: 2-Aminoadipic Acid; Genotype; Lysine; Mutation; Saccharomycetales; Schizosaccharomyces | 1988 |
alpha-Aminoadipate as a primary nitrogen source for Saccharomyces cerevisiae mutants.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Ammonia; Lysine; Mutation; Nitrogen; Saccharomyces cerevisiae | 1985 |
alpha-Aminoadipate.
Topics: 2-Aminoadipic Acid; Alcaligenes; Amino Acids, Dicarboxylic; Animals; Anti-Bacterial Agents; Biological Transport; Chemical Phenomena; Chemistry; Colorimetry; Flavobacterium; Kinetics; Lactams; Liver; Lysine; Optical Rotation; Pseudomonas; Species Specificity | 1985 |
A patient with alpha-ketoadipic and alpha-aminoadipic aciduria.
Topics: 2-Aminoadipic Acid; Adipates; Amino Acid Metabolism, Inborn Errors; Amino Acids, Dicarboxylic; Child; Dietary Proteins; Fibroblasts; Humans; Lysine; Male; Pipecolic Acids; Tryptophan | 1984 |
Tryptophan and lysine metabolism in alpha-aminoadipic aciduria.
Topics: 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Child; Humans; Intellectual Disability; Lysine; Male; Metabolism, Inborn Errors; Tryptophan | 1980 |
L-lysine epsilon-aminotransferase involved in cephamycin C synthesis in Streptomyces lactamdurans.
Topics: 2-Aminoadipic Acid; Cephalosporins; Cephamycins; Fermentation; Lysine; Pipecolic Acids; Stereoisomerism; Streptomyces; Transaminases | 1980 |
Lysine-derived cross-links in the egg shell membrane.
Topics: 2-Aminoadipic Acid; Amino Acids; Amino Acids, Dicarboxylic; Animals; Borohydrides; Desmosine; Egg Shell; Lysine; Membrane Proteins | 1981 |
Lysine metabolism in the human and the monkey: demonstration of pipecolic acid formation in the brain and other organs.
Topics: 2-Aminoadipic Acid; Adult; Animals; Brain; Female; Humans; Kidney; Liver; Lysine; Macaca mulatta; Pipecolic Acids; Spinal Cord | 1982 |
Hyperpipecolic acidemia. Occurrence in an infant with clinical findings of the cerebrohepatorenal (Zellweger) syndrome.
Topics: 2-Aminoadipic Acid; Abnormalities, Multiple; Bone and Bones; Bone Diseases; Facial Asymmetry; Female; Humans; Hypoprothrombinemias; Infant; Jaundice; Kidney Diseases; Kidney Diseases, Cystic; Liver Diseases; Lysine; Muscle Hypotonia; Pipecolic Acids; Skull; Syndrome | 1982 |
Repression of the genes for lysine biosynthesis in Saccharomyces cerevisiae is caused by limitation of Lys14-dependent transcriptional activation.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Reporter; Lysine; Molecular Sequence Data; Mutagenesis; Recombinant Fusion Proteins; Restriction Mapping; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine Endopeptidases; Trans-Activators; Transcription, Genetic | 1994 |
Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesis.
Topics: 2-Aminoadipic Acid; Lysine; Penicillins; Penicillium chrysogenum; Pipecolic Acids | 1994 |
Subcellular compartmentation of penicillin biosynthesis in Penicillium chrysogenum. The amino acid precursors are derived from the vacuole.
Topics: 2-Aminoadipic Acid; Amino Acids; Cell-Free System; Lysine; Models, Biological; Penicillins; Penicillium chrysogenum; Peptide Synthases; Polyphosphates; Protoplasts; Subcellular Fractions; Vacuoles; Valine | 1993 |
Analysis of swainsonine and its early metabolic precursors in cultures of Metarhizium anisopliae.
Topics: 2-Aminoadipic Acid; Chromatography, High Pressure Liquid; Lysine; Mitosporic Fungi; Pipecolic Acids; Swainsonine | 1997 |
Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Cephamycins; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Kinetics; L-Lysine 6-Transaminase; Lysine; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Picolinic Acids; Pipecolic Acids; Piperidines; Pyrroles; Quaternary Ammonium Compounds; Streptomyces; Substrate Specificity; Transaminases | 1997 |
Lys80p of Saccharomyces cerevisiae, previously proposed as a specific repressor of LYS genes, is a pleiotropic regulatory factor identical to Mks1p.
Topics: 2-Aminoadipic Acid; Citric Acid Cycle; Cloning, Molecular; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Suppressor; Ketoglutaric Acids; Lysine; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors | 1997 |
Twenty-four-hour intravenous and oral tracer studies with L-[1-13C]-2-aminoadipic acid and L-[1-13C]lysine as tracers at generous nitrogen and lysine intakes in healthy adults.
Topics: 2-Aminoadipic Acid; Administration, Oral; Adult; Carbon Isotopes; Female; Food; Humans; Infusions, Intravenous; Kinetics; Lysine; Male; Nitrogen; Nutritional Requirements; Oxidation-Reduction | 1998 |
Lysine is synthesized through the alpha-aminoadipate pathway in Thermus thermophilus.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Cloning, Molecular; Genes, Bacterial; Genes, Fungal; Hydro-Lyases; Lysine; Molecular Sequence Data; Mutation; Open Reading Frames; Oxo-Acid-Lyases; Saccharomyces cerevisiae; Sequence Alignment; Thermus thermophilus | 1998 |
Aspartate kinase-independent lysine synthesis in an extremely thermophilic bacterium, Thermus thermophilus: lysine is synthesized via alpha-aminoadipic acid not via diaminopimelic acid.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Aspartate Kinase; Base Sequence; Cloning, Molecular; Diaminopimelic Acid; DNA, Bacterial; Genes, Bacterial; Genetic Complementation Test; Hydro-Lyases; Lysine; Molecular Sequence Data; Multigene Family; Mutation; Plasmids; Thermus thermophilus | 1999 |
In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p.
Topics: 2-Aminoadipic Acid; Base Sequence; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Feedback; Fungal Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Fungal; Isoenzymes; Kinetics; Lysine; Mutation; Oxo-Acid-Lyases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Subcellular Fractions; Trans-Activators | 1999 |
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.
Topics: 2-Aminoadipic Acid; Acyl Carrier Protein; Aldehyde Oxidoreductases; Carbocysteine; Escherichia coli; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; NADP; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Sulfur Radioisotopes | 1999 |
A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis.
Topics: 2-Aminoadipic Acid; Amino Acids; Evolution, Molecular; Gene Transfer Techniques; Genes, Bacterial; Lysine; Multigene Family; Phylogeny; Pyrococcus; Thermus thermophilus | 1999 |
Overexpression of the lys1 gene in Penicillium chrysogenum: homocitrate synthase levels, alpha-aminoadipic acid pool and penicillin production.
Topics: 2-Aminoadipic Acid; Base Sequence; Chromatography, High Pressure Liquid; DNA Primers; Genetic Vectors; Lysine; Oxo-Acid-Lyases; Penicillins; Penicillium chrysogenum | 2000 |
Mechanism of formation of elastin crosslinks.
Topics: 2-Aminoadipic Acid; Aldehydes; Amino Acids; Butylamines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cross-Linking Reagents; Desmosine; Elastin; Hydrogen-Ion Concentration; Isodesmosine; Lysine; Pyridinium Compounds | 2000 |
The catabolic function of the alpha-aminoadipic acid pathway in plants is associated with unidirectional activity of lysine-oxoglutarate reductase, but not saccharopine dehydrogenase.
Topics: 2-Aminoadipic Acid; Arabidopsis; Gene Deletion; Genes, Fungal; Genes, Plant; Genetic Complementation Test; Lysine; Multienzyme Complexes; Oxo-Acid-Lyases; Protein Structure, Tertiary; Protein Transport; Saccharopine Dehydrogenases; Yeasts | 2000 |
What is characteristic of fungal lysine synthesis through the alpha-aminoadipate pathway?
Topics: 2-Aminoadipic Acid; Aldehyde Oxidoreductases; Amino Acid Sequence; Evolution, Molecular; Fungi; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Phylogeny; Saccharomyces cerevisiae; Saccharopine Dehydrogenases; Sequence Homology, Amino Acid | 2000 |
Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Fungal Proteins; Hydrogen Bonding; Ligands; Lysine; Magnaporthe; Models, Molecular; Molecular Sequence Data; NADP; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharopine Dehydrogenases | 2000 |
Functional and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate.
Topics: 2-Aminoadipic Acid; Arginine; Bacterial Proteins; Cloning, Molecular; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Evolution, Molecular; Ketoglutaric Acids; Kinetics; Lysine; Ornithine; Sequence Analysis, DNA; Thermus thermophilus; Transaminases | 2001 |
The proper folding of a long C-terminal segment of the yeast Lys14p regulator is required for activation of LYS genes in response to the metabolic effector.
Topics: 2-Aminoadipic Acid; Culture Media; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Lysine; Point Mutation; Protein Folding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators; Transcription, Genetic | 2002 |
Oxidative deamination of lysine residue in plasma protein of diabetic rats. Novel mechanism via the Maillard reaction.
Topics: 2-Aminoadipic Acid; Animals; Blood Proteins; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Copper; Diabetes Mellitus, Experimental; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Maillard Reaction; Male; Models, Chemical; Oxidation-Reduction; Oxygen; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Temperature; Time Factors | 2002 |
Crystal structure of a lysine biosynthesis enzyme, LysX, from Thermus thermophilus HB8.
Topics: 2-Aminoadipic Acid; Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Enzymes; Escherichia coli Proteins; Lysine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Processing, Post-Translational; Ribosomal Protein S6; Thermus thermophilus | 2003 |
On the glutamic family and lysine in Neurospora; enzymic formation of glutamic gamma-semialdehyde and alpha-aminoadipic delta-semialdehyde from penta-and hexahomoserine.
Topics: 2-Aminoadipic Acid; Amino Acids; Glutamates; Lysine; Neurospora; Oligosaccharides; Oxidoreductases; Rubiaceae | 1957 |
Studies in lysine biosynthesis. II. Metabolic fate of DL-alpha-aminoadipic acid-6-C14 in T. utilis.
Topics: 2-Aminoadipic Acid; Amino Acids; Lysine | 1961 |
Biosynthesis of cephalosporin C.
Topics: 2-Aminoadipic Acid; Anti-Bacterial Agents; Cephalosporins; Cysteine; Lysine; Methionine | 1962 |
Studies in lysine biosynthesis. IV. Mechanism of activation and reduction of alpha-aminoadipic acid.
Topics: 2-Aminoadipic Acid; Adipates; Amino Acids; Diphosphates; Lysine; Oxidoreductases | 1962 |
LYSINE BIOSYNTHESIS IN YEAST: A NEW METABOLITE OF ALPHA-AMINOADIPIC ACID.
Topics: 2-Aminoadipic Acid; Adipates; Carbon Isotopes; Chromatography; Infrared Rays; Lysine; Proteins; Research; Saccharomyces; Saccharomyces cerevisiae; X-Ray Diffraction | 1964 |
A metabolite of alpha-aminoadipic acid in yeast: relation to lysine biosynthesis.
Topics: 2-Aminoadipic Acid; Amino Acids; Lysine; Saccharomyces cerevisiae; Yeasts | 1962 |
Studies in lysine biosynthesis. III. Enzymatic reduction of alpha-aminoadipic acid: isolation and some properties of the enzyme.
Topics: 2-Aminoadipic Acid; Amino Acids; Enzymes; Lysine | 1962 |
The effect of an elevated maternal lysine concentration on placental lysine transport in pregnant sheep.
Topics: 2-Aminoadipic Acid; Amino Acids; Animals; Biological Transport; Female; Fetal Blood; Fetus; Lysine; Osmolar Concentration; Placenta; Pregnancy; Pregnancy, Animal; Sheep | 2003 |
Inactivation of the lys7 gene, encoding saccharopine reductase in Penicillium chrysogenum, leads to accumulation of the secondary metabolite precursors piperideine-6-carboxylic acid and pipecolic acid from alpha-aminoadipic acid.
Topics: 2-Aminoadipic Acid; Carboxylic Acids; Culture Media; Fungal Proteins; Gene Deletion; Lysine; Penicillium chrysogenum; Pipecolic Acids; Saccharopine Dehydrogenases; Transformation, Genetic | 2004 |
Alpha-Aminoadipic acid as a precursor to lysine in Neurospora.
Topics: 2-Aminoadipic Acid; Fungi; Lysine; Neurospora | 1951 |
Synthesis and antifungal properties of compounds which target the alpha-aminoadipate pathway.
Topics: 2-Aminoadipic Acid; Alkylation; Antifungal Agents; Aspergillus nidulans; Biomass; Citrates; Culture Media; Indicators and Reagents; Lysine; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Stereoisomerism | 2004 |
Biochemistry: is pyrroloquinoline quinone a vitamin?
Topics: 2-Aminoadipic Acid; Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Body Weight; Diet; Evolution, Molecular; L-Aminoadipate-Semialdehyde Dehydrogenase; Liver; Lysine; Mice; PQQ Cofactor; Proteins; Rats; Repetitive Sequences, Amino Acid; Reproducibility of Results; Vitamins | 2005 |
Lysine is catabolized to 2-aminoadipic acid in Penicillium chrysogenum by an omega-aminotransferase and to saccharopine by a lysine 2-ketoglutarate reductase. Characterization of the omega-aminotransferase.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Base Sequence; Chromatography, High Pressure Liquid; Lysine; Molecular Sequence Data; Penicillins; Penicillium chrysogenum; Saccharopine Dehydrogenases; Sequence Analysis, DNA; Transaminases | 2005 |
Characterization of the oat1 gene of Penicillium chrysogenum encoding an omega-aminotransferase: induction by L-lysine, L-ornithine and L-arginine and repression by ammonium.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Arginine; Base Sequence; Blotting, Northern; Cloning, Molecular; Conserved Sequence; DNA Primers; DNA, Complementary; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Introns; Lysine; Molecular Sequence Data; Mutation; Ornithine; Penicillium chrysogenum; Promoter Regions, Genetic; Quaternary Ammonium Compounds; Sequence Analysis, DNA; Transaminases; Transcription Factors | 2005 |
Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440.
Topics: 2-Aminoadipic Acid; Amino Acid Isomerases; Bacterial Proteins; Carbon; Carbon Radioisotopes; DNA Transposable Elements; Enzymes; Gas Chromatography-Mass Spectrometry; Genes, Bacterial; Glutarates; Lysine; Mutagenesis, Insertional; Mutation; Nitrogen; Pipecolic Acids; Piperidines; Pseudomonas putida; Valerates | 2005 |
A new microbial method for more efficient production of Nalpha-benzyloxycarbonyl-L-aminoadipate delta-semialdehyde and Nalpha-benzyloxycarbonyl-D-aminoadipate delta-semialdehyde.
Topics: 2-Aminoadipic Acid; Biotechnology; Lysine; Rhodococcus | 2005 |
Pyrroloquinoline quinone nutritional status alters lysine metabolism and modulates mitochondrial DNA content in the mouse and rat.
Topics: 2-Aminoadipic Acid; Animals; DNA, Mitochondrial; Female; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Mice; Nutritional Status; PQQ Cofactor; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
A novel type of lysine oxidase: L-lysine-epsilon-oxidase.
Topics: 2-Aminoadipic Acid; Amino Acid Oxidoreductases; Catalysis; Cloning, Molecular; Deamination; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Lysine; Marinomonas; Proteins; Substrate Specificity | 2006 |
Insights into the autotrophic CO2 fixation pathway of the archaeon Ignicoccus hospitalis: comprehensive analysis of the central carbon metabolism.
Topics: 2-Aminoadipic Acid; Acetyl Coenzyme A; Archaea; Autotrophic Processes; Carbon; Carbon Dioxide; Carbon Isotopes; Citrate (si)-Synthase; Citric Acid; Fructose-Bisphosphate Aldolase; Gluconeogenesis; Glycolysis; Hexosephosphates; Isoleucine; Lysine; Magnetic Resonance Spectroscopy; Malates; Models, Biological; Molecular Structure; Oxaloacetic Acid; Pentosephosphates; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxylase; Pyruvate Synthase; Pyruvates | 2007 |
Characterization of Nalpha-benzyloxycarbonyl-L-lysine oxidizing enzyme from Rhodococcus sp. AIU Z-35-1.
Topics: 2-Aminoadipic Acid; Enzyme Activation; Enzyme Stability; Lysine; Oxidation-Reduction; Oxidoreductases; Rhodococcus; Substrate Specificity | 2007 |
The degradation of l-lysine in guinea pig liver homogenate; formation of alpha-aminoadipic acid.
Topics: 2-Aminoadipic Acid; Guinea Pigs; Liver; Lysine | 1948 |
On the failure to utilize alpha-aminoadipic acid as a precursor of lysine by rats and certain bacteria.
Topics: 2-Aminoadipic Acid; Acids; Animals; Bacteria; Lysine; Rats | 1949 |
Aging, diabetes, and renal failure catalyze the oxidation of lysyl residues to 2-aminoadipic acid in human skin collagen: evidence for metal-catalyzed oxidation mediated by alpha-dicarbonyls.
Topics: 2-Aminoadipic Acid; Adolescent; Adult; Aging; Child; Child, Preschool; Collagen; Diabetes Mellitus; Diabetic Nephropathies; Humans; Infant; Infant, Newborn; Lysine; Middle Aged; Oxidation-Reduction; Skin; Skin Aging | 2008 |
Alpha-Aminoadipic acid; a product of lysine metabolism.
Topics: 2-Aminoadipic Acid; Amino Acids; Antifibrinolytic Agents; Lysine | 1948 |
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Bacterial Proteins; Escherichia coli; Genes, Bacterial; Lysine; Molecular Sequence Data; Multigene Family; Plasmids; Protein Conformation; Sequence Alignment; Thermus thermophilus | 2009 |
Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes.
Topics: 2-Aminoadipic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Cattle; Child; Crystallins; Diabetes Mellitus; Humans; Hydrogen Peroxide; Hyperbaric Oxygenation; Lens, Crystalline; Leucine; Lysine; Metals; Mice; Mice, Inbred C57BL; Middle Aged; Molecular Structure; Oxidants; Oxidation-Reduction; Rabbits; Regression Analysis; Young Adult | 2009 |
Enzymes responsible for the conversion of N alpha-[(Benzyloxy)carbonyl]-D-lysine to N alpha-[(Benzyloxy)carbonyl]-D-aminoadipic acid by Rhodococcus sp. AIU Z-35-1.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Bacterial Proteins; L-Amino Acid Oxidase; Lysine; Rhodococcus; Time Factors | 2010 |
Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I.
Topics: 2-Aminoadipate Transaminase; 2-Aminoadipic Acid; Amino Acid Metabolism, Inborn Errors; Analysis of Variance; Animals; Arginine; Brain; Brain Diseases, Metabolic; Carnitine; Catalase; Glutaryl-CoA Dehydrogenase; Ketoglutaric Acids; Lysine; Mice | 2011 |
A QM/MM-based computational investigation on the catalytic mechanism of saccharopine reductase.
Topics: 2-Aminoadipic Acid; Catalysis; Glutamic Acid; Lysine; Magnaporthe; NADP; Saccharopine Dehydrogenases | 2011 |
The measurement of urinary Δ¹-piperideine-6-carboxylate, the alter ego of α-aminoadipic semialdehyde, in Antiquitin deficiency.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Diet; Epilepsy; Humans; Lysine; Picolinic Acids | 2012 |
Urinary AASA excretion is elevated in patients with molybdenum cofactor deficiency and isolated sulphite oxidase deficiency.
Topics: 2-Aminoadipic Acid; Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Coenzymes; Cysteine; Humans; Infant, Newborn; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Metabolic Networks and Pathways; Metal Metabolism, Inborn Errors; Metalloproteins; Models, Biological; Molybdenum Cofactors; Molybdoferredoxin; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Sulfite Oxidase; Sulfites | 2012 |
Lysine restricted diet for pyridoxine-dependent epilepsy: first evidence and future trials.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Child; Child, Preschool; Cognition; Diet; Epilepsy; Female; Humans; Infant; Longitudinal Studies; Lysine; Male; Pipecolic Acids; Pyridoxine | 2012 |
The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate.
Topics: 2-Aminoadipic Acid; Aconitate Hydratase; Biosynthetic Pathways; Energy Metabolism; Fungi; Lysine; Tricarboxylic Acids | 2012 |
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
Topics: 2-Aminoadipic Acid; Archaeal Proteins; Arginine; Bacterial Proteins; Carrier Proteins; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Evolution, Molecular; Gene Duplication; Glutamic Acid; Lysine; Models, Molecular; Ornithine; Phylogeny; Protein Binding; Protein Interaction Domains and Motifs; Recombinant Proteins; Substrate Specificity; Sulfolobus acidocaldarius; Thermus | 2013 |
Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus.
Topics: 2-Aminoadipic Acid; Anti-Bacterial Agents; Cephamycins; Culture Media; Diamines; Humans; Industrial Microbiology; Lysine; Models, Theoretical; Streptomyces | 2013 |
Steady-state kinetic mechanism of LodA, a novel cysteine tryptophylquinone-dependent oxidase.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Coenzymes; Dipeptides; Hydrogen-Ion Concentration; Indolequinones; Kinetics; Lysine; Marinomonas; Models, Chemical; Proteins | 2014 |
Phenotypic consequences of LYS4 gene disruption in Candida albicans.
Topics: 2-Aminoadipic Acid; Animal Structures; Animals; Candida albicans; Candidiasis; Colony Count, Microbial; Culture Media; Disease Models, Animal; Fungal Proteins; Gene Knockout Techniques; Lysine; Mice; Virulence | 2014 |
Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ·LysW complex from Thermus thermophilus.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Escherichia coli; Gene Expression; Ketoglutaric Acids; Lysine; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Static Electricity; Substrate Specificity; Thermus thermophilus | 2015 |
Regulation of free glutamate content in meat by dietary lysine in broilers.
Topics: 2-Aminoadipic Acid; Animal Feed; Animals; Chickens; Dietary Supplements; Female; Food Quality; Glutamic Acid; Liver; Lysine; Meat; Muscles; Pipecolic Acids; RNA, Messenger; Saccharopine Dehydrogenases | 2015 |
(1) H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness.
Topics: 2-Aminoadipic Acid; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Cell Survival; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Lysine; Male; Metabolic Networks and Pathways; Mitochondria; Multivariate Analysis; Neoplasm Invasiveness; Neoplastic Stem Cells; Proton Magnetic Resonance Spectroscopy; Signal Processing, Computer-Assisted | 2015 |
Effect of charged amino acid side chain length on lateral cross-strand interactions between carboxylate- and guanidinium-containing residues in a β-hairpin.
Topics: 2-Aminoadipic Acid; Alanine; Arginine; Aspartic Acid; Databases, Protein; Glutamic Acid; Guanidines; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lysine; Models, Molecular; Protein Folding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protein Structure, Tertiary; Static Electricity; Thermodynamics | 2015 |
Activity of α-Aminoadipate Reductase Depends on the N-Terminally Extending Domain.
Topics: 2-Aminoadipic Acid; Basidiomycota; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Models, Molecular; Protein Structure, Tertiary | 2015 |
Molecular characterization of lysR-lysXE, gcdR-gcdHG and amaR-amaAB operons for lysine export and catabolism: a comprehensive lysine catabolic network in Pseudomonas aeruginosa PAO1.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Base Sequence; Biological Transport; Carboxy-Lyases; Coenzyme A-Transferases; DNA-Binding Proteins; DNA, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genome, Bacterial; Glutarates; Glutaryl-CoA Dehydrogenase; Lysine; Pipecolic Acids; Promoter Regions, Genetic; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Deletion; Transaminases; Transcription Factors; Transcriptional Activation | 2016 |
Mouse lysine catabolism to aminoadipate occurs primarily through the saccharopine pathway; implications for pyridoxine dependent epilepsy (PDE).
Topics: 2-Aminoadipic Acid; Animals; Epilepsy; Female; Lysine; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Picolinic Acids; Pyridoxal Phosphate | 2017 |
Phenotype, biochemical features, genotype and treatment outcome of pyridoxine-dependent epilepsy.
Topics: 2-Aminoadipic Acid; Adolescent; Aldehyde Dehydrogenase; Arginine; Child; Child, Preschool; Cohort Studies; Epilepsy; Female; Genotype; Humans; Infant; Lysine; Male; Mutation, Missense; Phenotype; Pyridoxine; Retrospective Studies; Seizures; Treatment Outcome; Vitamins | 2017 |
A Genetically Encoded Allysine for the Synthesis of Proteins with Site-Specific Lysine Dimethylation.
Topics: 2-Aminoadipic Acid; Escherichia coli; Genetic Code; Histones; Humans; Lysine; Methylation; Models, Molecular; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Tumor Suppressor Protein p53 | 2017 |
Importance of the C-Terminus of Aldehyde Dehydrogenase 7A1 for Oligomerization and Catalytic Activity.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Biocatalysis; Epilepsy; Humans; Kinetics; Lysine; Protein Multimerization; Protein Structure, Quaternary; Substrate Specificity | 2017 |
Elastin is heterogeneously cross-linked.
Topics: 2-Aminoadipic Acid; Animals; Biopolymers; Cattle; Desmosine; Dipeptides; Elastin; Humans; Lysine; Protein Domains; Tropoelastin | 2018 |
New insights into human lysine degradation pathways with relevance to pyridoxine-dependent epilepsy due to antiquitin deficiency.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Epilepsy; Humans; Lysine; Metabolic Networks and Pathways; Pipecolic Acids; Vitamin B 6 | 2019 |
Simultaneous quantification of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate, pipecolic acid and alpha-aminoadipic acid in pyridoxine-dependent epilepsy.
Topics: 2-Aminoadipic Acid; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Epilepsy; Female; Humans; Infant; Lysine; Male; Mass Screening; Picolinic Acids; Pipecolic Acids; Tandem Mass Spectrometry | 2019 |
Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies.
Topics: 2-Aminoadipic Acid; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet, Mediterranean; Female; Humans; Incidence; Lysine; Male; Middle Aged; Pipecolic Acids; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Risk Reduction Behavior; Time Factors; Treatment Outcome | 2019 |
An in vitro assay of the effect of lysine oxidation end-product, α-aminoadipic acid, on the redox status and gene expression in probiotic Lactobacillus reuteri PL503.
Topics: 2-Aminoadipic Acid; Amino Acids; Gene Expression; Limosilactobacillus reuteri; Lysine; Oxidation-Reduction; Probiotics | 2022 |
Efficient biosynthesis of α-aminoadipic acid via lysine catabolism in Escherichia coli.
Topics: 2-Aminoadipic Acid; Escherichia coli; Lysine; Saccharomyces cerevisiae; Saccharopine Dehydrogenases | 2023 |