2-amino-7-phosphonoheptanoic acid has been researched along with n-methylaspartate in 110 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (36.36) | 18.7374 |
| 1990's | 50 (45.45) | 18.2507 |
| 2000's | 10 (9.09) | 29.6817 |
| 2010's | 10 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Hisanaga, K; Sagar, SM; Sharp, FR | 1 |
| Lu, CL; Shaikh, MB; Siegel, A | 1 |
| De Sarro, A; De Sarro, G; Meldrum, BS; Patel, S | 1 |
| Grigor'ev, VV; Nemanova, VA; Ragulin, VV | 1 |
| Conti, L; Ellenberger, SR; Ellenberger, WP; Ferkany, JW; Guzewska, ME; Hudkins, R; Kyle, DJ; Narayanan, BA; Patch, R; Rzeszotarski, WJ | 1 |
| Beninger, RJ; Jhamandas, K; Thanos, PK | 1 |
| Fragoso-Veloz, J; Tapia, R | 1 |
| Boje, K; Miller, R; Skolnick, P; Trullas, R; Young, A | 1 |
| Clark, D; Overton, P | 2 |
| Denavit-Saubie, M; Foutz, AS; Pierrefiche, O; Schmid, K | 1 |
| Anderton, PJ; Millar, TJ | 1 |
| Dougherty, PM; Willis, WD | 1 |
| Sapru, H; Sundaram, K | 1 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Bigalke, H; Lampe, H | 1 |
| Linn, DM; Massey, SC | 1 |
| Chai, CY; Kao, MC; Lee, HK; Wang, Y | 1 |
| Insel, TR; Skolnick, P; Trullas, R; Winslow, JT | 1 |
| Ohno, Y; Warnick, JE | 1 |
| Liu, GQ; Ping, HX; Wu, HQ | 1 |
| Massey, SC; Miller, RF | 1 |
| Butler, TW; Butterfield, GC; Chenard, BL; Dominy, BW; Lipinski, CA; Marinovic, LC; Mena, EE; Pagnozzi, M; Ronau, RT; Tsang, T | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Halsey, MJ; Meldrum, BS; Millan, MH; Wardley-Smith, B | 2 |
| Coenen, AM; Peeters, BW; van Rijn, CM; Vossen, JM | 1 |
| Baker, RE; Ruijter, JM | 1 |
| Jope, RS; Li, X; Ormandy, GC | 1 |
| Rogers, BC; Tilson, HA | 1 |
| Buerki, H; Fagg, GE; Mondadori, C; Petschke, F; Weiskrantz, L | 1 |
| Bartkowski, H; Roman, R; Simon, R | 1 |
| Clow, DW; Jhamandas, K | 1 |
| Ogita, K; Yoneda, Y | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| Ben-Ari, Y; Cherubini, E; King, AE | 1 |
| McCaslin, PP; Morgan, WW | 3 |
| Evans, MC; Meldrum, BS; Swan, JH | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Wamil, A | 1 |
| De Prins, E; Marrannes, R; Wauquier, A; Willems, R | 1 |
| Jacquet, YF; Squires, RF | 1 |
| Jacquet, YF | 1 |
| Collins, JF; Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Carpenter, DO; Ffrench-Mullen, JM; Hori, N | 2 |
| Canning, HM; Leach, MJ; Marden, CM | 1 |
| Stone, TW | 1 |
| Samanin, R; Vezzani, A; Wu, HQ | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Ben-Ari, Y; Cherubini, E; Neuman, R | 1 |
| Kapetanovic, IM; Kupferberg, HJ; Torchin, CD; Yonekawa, WD | 1 |
| Beart, PM; Davies, SN; Jones, MG; Lodge, D; Manallack, DT; Millar, J; Ornstein, PL; Verberne, AJ; Young, N | 1 |
| Wieloch, T | 1 |
| Cavalheiro, EA; Meldrum, BS; Turski, L; Turski, WA | 1 |
| Ho, PM; Tang, AH | 1 |
| Cherubini, E; Herrling, PL; Lanfumey, L; Stanzione, P | 1 |
| Balster, RL; Willetts, J | 1 |
| Compton, RP; Contreras, PC; Monahan, JB; O'Donohue, TL | 1 |
| Do, KQ; Herrling, PL; Turski, WA | 1 |
| Boast, CA; Pastor, G | 1 |
| Balm, M; Coyle, JT; Markl, A; Zaczek, R | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 1 |
| Collins, JF; Croucher, MJ; Curry, K; Czuczwar, SJ; Joseph, M; Meldrum, BS; Stone, TW | 1 |
| Czuczwar, SJ; Meldrum, B | 1 |
| Perkins, MN; Stone, TW | 2 |
| Collins, JF; Perkins, MN; Stone, TW | 1 |
| Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Block, F | 1 |
| Block, F; Schmitt, T; Schwarz, M | 1 |
| Evrard, P; Gadisseux, JF; Gressens, P; Marret, S; Mukendi, R | 1 |
| Lowry, T; Simon, RP; Tanaka, K | 1 |
| Cabrera, RJ; Donoso, AO; Navarro, CE | 1 |
| Garcia-Cairasco, N; Terra, VC | 1 |
| Faiman, CP; Skolnick, P; Trullas, R; Viu, E | 1 |
| Ebner, TJ; Elias, SA; Yae, H | 1 |
| Sluka, KA; Westlund, KN | 1 |
| Block, F; Schwarz, M | 1 |
| Bradford, HF; Cotterell, KL; Croucher, MJ | 2 |
| Cabrera, RJ; Navarro, CE | 1 |
| Yamazaki, M | 1 |
| Beninger, RJ; Boegman, RJ; Flesher, S; Jhamandas, KH; Pawley, AC | 1 |
| Tang, H; Yamamoto, H | 1 |
| Bhatnagar, T; Chitravanshi, VC; Sapru, HN | 1 |
| Dirnagl, U; Isaev, N; Stelmashook, EV; Victorov, I; Weih, M; Zorov, D | 1 |
| Darbin, O; Risso, JJ; Rostain, JC | 1 |
| Barat, A; Burgos, JS; Ramírez, G | 1 |
| Alvarado, R; Camacho-Arroyo, I; Manjarrez, J | 1 |
| Sitniewska, EM; Wiśniewska, RJ; Wiśniewski, K | 1 |
| Kaczyńska, K; Szereda-Przestaszewska, M | 1 |
| Bertoglio, LJ; Guimarães, FS; Zangrossi, H | 1 |
| Bertoglio, LJ; Zangrossi, H | 1 |
| Chrapusta, SJ; Kaczyńska, K; Szereda-Przestaszewska, M | 1 |
| Heinmiller, A; Ting-A-Kee, R; van der Kooy, D; Vargas-Perez, H; Yeh, A | 1 |
| Brandão, ML; Coimbra, NC; Ferrari, EA; Francisco, A; Maisonnette, SS; Medeiros, P; Mello, RO; Melo, LL; Santos, P | 1 |
| Aguiar, DC; Guimarães, FS | 1 |
| Cabrera, R; Giuliani, FA; Laconi, M; Mohn, CE; Rettori, V; Yunes, R | 1 |
| Barbosa-Silva, R; Iacopucci, AP; Mello, RO; Melo-Thomas, L | 1 |
| Hosseini, N; Nasehi, M; Radahmadi, M; Zarrindast, MR | 1 |
| Bum, EN; Moto, FC; Ngoupaye, GT; Taiwe, GS; Talla, E | 1 |
| Nasehi, M; Oryan, S; Rasekhi, K; Zarrindast, MR | 1 |
| Amin-Yavari, S; Ebrahimi-Ghiri, M; Nasehi, M; Torabi-Nami, M; Zarrindast, MR | 1 |
| Khakpai, F; Nasehi, M; Zarrindast, MR | 1 |
| Chitravanshi, VC; Kawabe, K; Sapru, HN | 1 |
110 other study(ies) available for 2-amino-7-phosphonoheptanoic acid and n-methylaspartate
| Article | Year |
|---|---|
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes | 1990 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Proto-Oncogene Proteins c-fos; Signal Transduction | 1992 |
Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Cats; Female; Hypothalamus, Middle; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Periaqueductal Gray; Quinoxalines; Rage; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Epilepsy; Glutamine; Kainic Acid; Limbic System; Male; N-Methylaspartate; Neurotransmitter Agents; Pilocarpine; Pons; Rats; Rats, Wistar; Thalamus | 1992 |
[Species differences in the action of concurrent NMDA receptor antagonists in mouse and rat hippocampal neurons].
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Hippocampus; Mice; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Species Specificity | 1992 |
Pharmacological profile of novel cyclic analogs of 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Electroshock; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship | 1992 |
N-methyl-D-aspartate unilaterally injected into the dorsal striatum of rats produces contralateral circling: antagonism by 2-amino-7-phosphonoheptanoic acid and cis-flupenthixol.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Corpus Striatum; Flupenthixol; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Rotation | 1992 |
NMDA receptor antagonists protect against seizures and wet-dog shakes induced by 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amino Acids; Animals; Behavior, Animal; Male; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures | 1992 |
Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-D-aspartate receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Learning; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Swimming | 1992 |
Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Corpus Striatum; Dopamine; Electrophysiology; Injections; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1992 |
Endogenous activation of NMDA and non-NMDA glutamate receptors on respiratory neurones in cat medulla.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Decerebrate State; Iontophoresis; Medulla Oblongata; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiratory Center | 1991 |
Effects of excitatory amino acids and their antagonists on the light response of luminosity and color-opponent horizontal cells in the turtle (Pseudemys scripta elegans) retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Color Perception; Dizocilpine Maleate; Electrophysiology; Kainic Acid; Light; N-Methylaspartate; Photic Stimulation; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles | 1991 |
Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Glutamates; Glutamic Acid; Macaca fascicularis; N-Methylaspartate; Neurons; Quisqualic Acid; Spinothalamic Tracts | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
An arthropod NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Astacoidea; Cesium; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Immunoenzyme Techniques; Interneurons; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1991 |
Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Carbamazepine; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Female; Ion Channels; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Phenytoin; Pregnancy; Spinal Cord | 1990 |
N-methyl-D-aspartate increases the excitability of nigrostriatal dopamine terminals.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Binding, Competitive; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Nerve Fibers; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Acetylcholine release from the rabbit retina mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Convulsants; Dizocilpine Maleate; Glycine; In Vitro Techniques; Light; Magnesium; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1991 |
NMDA antagonists attenuate hypertension induced by carotid clamping in the rostral ventrolateral medulla of rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Arterial Occlusive Diseases; Blood Pressure; Carotid Arteries; Carotid Artery Diseases; Cerebral Ventricles; Hypertension; Injections, Intraventricular; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Pain; Phencyclidine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Vagotomy | 1991 |
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Female; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Social Isolation; Vocalization, Animal | 1990 |
Selective depression of the segmental polysynaptic reflex by phencyclidine and its analogs in the rat in vitro: interaction with N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Haloperidol; In Vitro Techniques; Magnesium; Male; Methiothepin; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Spinal Cord | 1990 |
Modulation of neuronal activity of locus coeruleus in rats induced by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Electrophysiology; Glutamates; Locus Coeruleus; Male; N-Methylaspartate; Neurons; Quinolinic Acids; Rats; Rats, Inbred Strains | 1990 |
N-methyl-D-aspartate receptors of ganglion cells in rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Valine | 1990 |
A unified approach to systematic isosteric substitution for acidic groups and application to NMDA antagonists related to 2-amino-7-phosphonoheptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Models, Molecular; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Effect of NMDA and 2-amino-7-phosphonoheptanoate focal injection into the ventrolateral thalamic nucleus on the high pressure neurological syndrome in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Central Nervous System Diseases; High Pressure Neurological Syndrome; Male; Microinjections; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamic Nuclei | 1990 |
Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electroencephalography; Epilepsy; Female; Injections, Intraventricular; Male; N-Methylaspartate; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
The effects of potassium-induced depolarization, glutamate receptor antagonists and N-methyl-D-aspartate on neuronal survival in cultured neocortex explants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cell Survival; Cerebral Cortex; Culture Techniques; Electrophysiology; Glutamates; N-Methylaspartate; Neurons; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1990 |
Dibenzocycloalkenimine (MK-801) stimulates phosphoinositide hydrolysis in rat cerebral cortical slices).
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atropine; Cerebral Cortex; Dizocilpine Maleate; Hydrolysis; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Phencyclidine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Zinc | 1990 |
Stereospecificity of N-MDA-induced functional deficits.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Hippocampus; Learning; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred F344; Stereoisomerism | 1990 |
NMDA receptor antagonists can enhance or impair learning performance in animals.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gerbillinae; Male; Memory; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
The specific NMDA receptor antagonist AP-7 attenuates focal ischemic brain injury.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Ischemic Attack, Transient; Kinetics; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Catalepsy; Globus Pallidus; Male; N-Methylaspartate; Nervous System Diseases; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Substantia Nigra; Syndrome | 1989 |
Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Oxadiazoles; Phenazocine; Potassium; Putamen; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Solubilization of quisqualate-sensitive [3H]glutamate binding activity from rat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Octoxynol; Oxadiazoles; Polyethylene Glycols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Solubility | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
N-methyl-D-aspartate induces recurrent synchronized burst activity in immature hippocampal CA3 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Tetrodotoxin | 1989 |
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
Long-term development of selective neuronal loss and the mechanism of protection by 2-amino-7-phosphonoheptanoate in a rat model of incomplete forebrain ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cell Survival; Cerebrovascular Circulation; Hippocampus; Ischemic Attack, Transient; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Inhibition of aminophylline-induced convulsions in mice by antiepileptic drugs and other agents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminophylline; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Female; Mice; N-Methylaspartate; Phenobarbital; Seizures; Synaptic Transmission; Valproic Acid | 1987 |
Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cortical Spreading Depression; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Excitatory amino acids: role in morphine excitation in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; Motor Activity; N-Methylaspartate; Oxadiazoles; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Muscle relaxant action of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Spasticity; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
A comparison of the effects of quinolinate and N-methyl-aspartate on neurons in rat piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Iontophoresis; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Rats; Valine | 1986 |
(+/-)-cis-2,3-Piperidine dicarboxylic acid is a partial N-methyl-D-aspartate agonist in the in vitro rat cerebellar cGMP model.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Continuously infused 2-amino-7-phosphonoheptanoic acid antagonizes N-methyl-D-aspartate-induced elevations of cyclic GMP in vivo in multiple brain areas and chemically-induced seizure activity.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Barbiturates; Bicuculline; Brain; Brain Chemistry; Cyclic GMP; Female; Injections, Intraventricular; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains | 1986 |
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1987 |
Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Homocysteine; Iontophoresis; Ketamine; Male; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Valine | 1988 |
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate and glutamine in mouse brain cortex.
Topics: 2-Amino-5-phosphonovalerate; 3-Mercaptopropionic Acid; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Male; Mice; N-Methylaspartate; Valproic Acid | 1988 |
A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; In Vitro Techniques; N-Methylaspartate; Neurons; Piperazines; Rats; Reflex; Spine; Valine | 1988 |
Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Electroencephalography; Hypoglycemia; Male; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1985 |
Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electroencephalography; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Stereotaxic Techniques; Substantia Nigra; Synaptic Transmission | 1986 |
2-Amino-7-phosphonoheptanoic acid, a selective N-methyl-D-aspartate antagonist, blocks swim-induced elevation of cerebellar cyclic guanosine monophosphate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Female; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Swimming | 1986 |
Both competitive and non-competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Light; Male; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred F344 | 1988 |
Excitatory amino acids in synaptic excitation of rat striatal neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Glutamates; Glutamine; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Synapses | 1988 |
The discriminative stimulus effects of N-methyl-D-aspartate antagonists in phencyclidine-trained rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Discrimination, Psychological; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Methohexital; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Time Factors | 1988 |
The N-methyl-D-aspartate antagonist, 2-amino-7-phosphonoheptanoate, produces phencyclidine-like behavioral effects in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1987 |
Effects of L-cysteine-sulphinate and L-aspartate, mixed excitatory amino acid agonists, on the membrane potential of cat caudate neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Cysteine; Female; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1987 |
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors | 1987 |
A simple method for quantitative electroencephalographic assessment of drugs with convulsant and anticonvulsant properties.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Diazepam; Electroencephalography; Hippocampus; Injections; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1986 |
N-Methyl-D-aspartate and L-aspartate activate distinct receptors in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Limbic System; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1984 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
A comparison of the anticonvulsant potency of (+/-) 2-amino-5-phosphonopentanoic acid and (+/-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Valine | 1983 |
Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Seizures | 1982 |
In vivo release of [3H]-purines by quinolinic acid and related compounds.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Kynurenic Acid; Male; N-Methylaspartate; Purines; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium | 1983 |
On the interaction of 2-amino-7-phosphono-heptanoic acid and quinolinic acid in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Iontophoresis; Male; Mice; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Seizures | 1983 |
Isomers of 2-amino-7-phosphonoheptanoic acid as antagonists of neuronal excitants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats | 1982 |
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Apnea; Blood Pressure; Cats; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Piperazines; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Respiration; Solitary Nucleus; Vagotomy | 1995 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Stimulation of N-methyl-D-aspartate receptors in the rat nucleus reticularis thalami suppresses somatosensory evoked potentials.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Somatosensory; Male; Microinjections; N-Methylaspartate; Nerve Fibers; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thalamic Nuclei | 1994 |
Pentamidine, an inhibitor of spinal flexor reflexes in rats, is a potent N-methyl-D-aspartate (NMDA) antagonist in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Drug Interactions; Electromyography; H-Reflex; Ibotenic Acid; Injections, Spinal; Male; N-Methylaspartate; Pentamidine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Stretch; Tibial Nerve | 1993 |
Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Brain; Brain Diseases; Embryonic and Fetal Development; Excitatory Amino Acids; Female; Glial Fibrillary Acidic Protein; Hypoxia; Ibotenic Acid; Male; Mice; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Bilateral intranigral NMDA blockade increases status duration and neuronal injury from systemic kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Carbon Dioxide; Diazepam; Drug Synergism; Electroencephalography; Functional Laterality; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Injections, Intravenous; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neurons; Oxygen; Partial Pressure; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors | 1994 |
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium | 1994 |
NMDA-dependent audiogenic seizures are differentially regulated by inferior colliculus subnuclei.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Brain Mapping; Epilepsy, Tonic-Clonic; Inferior Colliculi; N-Methylaspartate; Neurons; Rats; Seizures; Synaptic Transmission | 1994 |
Differential effects of compounds that act at strychnine-insensitive glycine receptors in a punishment procedure.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Diazepam; Learning; Male; Memory; Mice; N-Methylaspartate; Punishment; Reaction Time; Receptors, Glycine; Strychnine | 1994 |
Optical imaging of parallel fiber activation in the rat cerebellar cortex: spatial effects of excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebellar Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
An experimental arthritis model in rats: the effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Aspartic Acid; Carrageenan; Glutamates; Glutamic Acid; Injections, Intra-Articular; Kaolin; Knee Joint; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of dextromethorphan in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Dextromethorphan; Electric Stimulation; Electromyography; H-Reflex; Injections, Intraperitoneal; Injections, Spinal; Male; Muscle Relaxation; Muscles; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reflex, Stretch | 1993 |
Amygdaloid kindling by repeated focal N-methyl-D-aspartate administration: comparison with electrical kindling.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Calcium; Excitatory Amino Acid Agonists; Kindling, Neurologic; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
Progesterone in vitro increases NMDA-evoked [3H] dopamine release from striatal slices in proestrus rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Corpus Striatum; Dizocilpine Maleate; Dopamine; Drug Synergism; Estrus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; N-Methylaspartate; Progesterone; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
Characterisation of N-methyl-D-aspartate (NMDA)-induced kindling.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Anticonvulsants; Electroencephalography; Kindling, Neurologic; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors | 1996 |
[The influence of intrathecal NMDA receptor antagonist on the isoflurane MAC and on the motor function].
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1996 |
Differential action of NMDA antagonists on cholinergic neurotoxicity produced by N-methyl-D-aspartate and quinolinic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Choline O-Acetyltransferase; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Effects of 2-amino-7-phosphonohepatanoic acid, melatonin or NG-nitro-L-arginine on cyanide or N-methyl-D-aspartate-induced neurotoxicity in rat cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radicals; In Vitro Techniques; L-Lactate Dehydrogenase; Melatonin; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Poisons; Potassium Cyanide; Rats | 1998 |
Cardiovascular responses to microinjections of excitatory amino acids into the area postrema of the rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Cerebral Ventricles; Cycloleucine; Decerebrate State; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Tachycardia; Urethane | 1999 |
Short-term block of Na+/K+-ATPase in neuro-glial cell cultures of cerebellum induces glutamate dependent damage of granule cells.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Binding, Competitive; Calcium; Cells, Cultured; Cerebellum; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium; N-Methylaspartate; Neuroglia; Ouabain; Rats; Rats, Wistar; Rhodamine 123; Sodium-Potassium-Exchanging ATPase; Xanthenes | 1999 |
High pressure enhanced NMDA activity in the striatum and the globus pallidus: relationships with myoclonia and locomotor and motor activity in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Atmospheric Pressure; Corpus Striatum; Excitatory Amino Acid Antagonists; Globus Pallidus; High Pressure Neurological Syndrome; Male; Motor Activity; Myoclonus; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 2000 |
Guanine nucleotides block agonist-driven 45Ca2+ influx in chick embryo retinal explants.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Calcium Radioisotopes; Chick Embryo; Excitatory Amino Acid Antagonists; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Monophosphate; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Thionucleotides | 2000 |
Differential effects of NMDA antagonists microinjections into the nucleus reticularis pontis caudalis on seizures induced by pentylenetetrazol in the rat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Pentylenetetrazole; Pons; Rats; Rats, Wistar; Reticular Formation; Seizures | 2001 |
The role of ionotropic receptors of glutaminic acid in cardiovascular system. A. The influence of ionotropic receptor NMDA agonist - 1R,3R-ACPD and antagonist - DL-AP7 on the systemic pressure in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Chlorisondamine; Cycloleucine; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2003 |
Carotid sinus nerve section abolishes NMDA evoked respiratory effects in anaesthetised rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Blood Pressure; Carotid Sinus; Denervation; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Pulmonary Ventilation; Rats; Rats, Wistar; Respiration; Tidal Volume; Time Factors; Vagotomy | 2005 |
Lack of interaction between NMDA and cholecystokinin-2 receptor-mediated neurotransmission in the dorsolateral periaqueductal gray in the regulation of rat defensive behaviors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gastrointestinal Agents; Male; Maze Learning; N-Methylaspartate; Periaqueductal Gray; Quinazolinones; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Signal Transduction; Tetragastrin | 2006 |
Involvement of dorsolateral periaqueductal gray N-methyl-D-aspartic acid glutamate receptors in the regulation of risk assessment and inhibitory avoidance behaviors in the rat elevated T-maze.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Anxiety; Ethosuximide; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Hippocampus; Male; Microinjections; N-Methylaspartate; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Risk-Taking | 2006 |
Non-vagal apnea evoked by intra-common carotid artery injection of N-methyl-D-aspartic acid (NMDA) in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Apnea; Blood Pressure; Carotid Sinus; Denervation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intra-Arterial; Male; N-Methylaspartate; Rats; Rats, Wistar; Respiration; Vagotomy; Vagus Nerve | 2006 |
Tegmental pedunculopontine glutamate and GABA-B synapses mediate morphine reward.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Morphine; N-Methylaspartate; Narcotics; Pedunculopontine Tegmental Nucleus; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Glutamate; Reward | 2009 |
Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synaptic Transmission | 2010 |
Blockade of NMDA or NO in the dorsal premammillary nucleus attenuates defensive behaviors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cats; Defense Mechanisms; Excitatory Amino Acid Antagonists; Fear; Freezing Reaction, Cataleptic; Locomotion; Male; Mammillary Bodies; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Statistics, Nonparametric | 2011 |
Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Estrogen Replacement Therapy; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Models, Animal; N-Methylaspartate; Neurotransmitter Agents; Ovariectomy; Pregnanolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Inferior Colliculi; Male; Microinjections; N-Methylaspartate; Nitroarginine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Time Factors | 2012 |
Effects of CA1 glutamatergic systems upon memory impairments in cholestatic rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; CA1 Region, Hippocampal; Cholestasis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Memory; Memory Disorders; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2013 |
Antidepressant properties of aqueous macerate from Gladiolus dalenii corms.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Fluoxetine; Hindlimb Suspension; Imipramine; Iridaceae; Male; Medicine, African Traditional; Mice; Motor Activity; N-Methylaspartate; Phytotherapy; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming | 2014 |
Involvement of the nucleus accumbens shell glutamatergic system in ACPA-induced impairment of inhibitory avoidance memory consolidation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acids; Avoidance Learning; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Memory; Memory Disorders; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Piperidines; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2014 |
The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Learning; CA1 Region, Hippocampal; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Mice; Microinjections; N-Methylaspartate; Piperidines; Pyrazoles; Receptors, N-Methyl-D-Aspartate | 2015 |
The role of NMDA receptors of the medial septum and dorsal hippocampus on memory acquisition.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; CA1 Region, Hippocampal; Excitatory Amino Acid Antagonists; Locomotion; Male; Memory; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2016 |
Stimulation of the hypothalamic arcuate nucleus increases brown adipose tissue nerve activity via hypothalamic paraventricular and dorsomedial nuclei.
Topics: 2-Amino-5-phosphonovalerate; Adipose Tissue, Brown; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA-A Receptor Agonists; Glutamic Acid; Immunohistochemistry; Male; Microinjections; Muscimol; N-Methylaspartate; Neural Inhibition; Paraventricular Hypothalamic Nucleus; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Stilbamidines; Sympathetic Nervous System; Temperature; Thermogenesis; Vesicular Glutamate Transport Proteins | 2016 |