2-amino-5-phosphonovalerate has been researched along with valine in 935 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 307 (32.83) | 18.7374 |
| 1990's | 53 (5.67) | 18.2507 |
| 2000's | 273 (29.20) | 29.6817 |
| 2010's | 300 (32.09) | 24.3611 |
| 2020's | 2 (0.21) | 2.80 |
| Authors | Studies |
|---|---|
| Felipo, V; Grisolía, S; Hermenegildo, C; Marcaida, G; Miñana, MD | 1 |
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Beckstead, RM; Somers, DL | 1 |
| Dreifuss, JJ; Raggenbass, M; Widmer, H | 1 |
| Isom, GE; Patel, MN; Yim, GK | 1 |
| Arslan, M; Plant, TM; Pohl, CR; Smith, MS | 1 |
| Baron, BM; Chi, EM; Harrison, BL; Kehne, JH; McCloskey, TC; Palfreyman, MG; Whitten, JP | 1 |
| Monaghan, DT | 1 |
| Fukushima, R; Kizu, A; Miyagishi, T; Ono, T; Yoshida, Y | 1 |
| Baud, J; Baumann, P; Bittiger, H; Fagg, GE; Olpe, HR; Portet, C; Pozza, MF; Schmutz, M; Steinmann, M; Thedinga, K | 1 |
| Clements, JD; Jahr, CE; Lester, RA; Westbrook, GL | 1 |
| Adams, RN; Bunney, BS; Gruen, RJ; Moghaddam, B; Roth, RH | 1 |
| Brugger, F; Fagg, GE; Olpe, HR; Pozza, MF | 1 |
| Crunelli, V; Emri, Z; Juhász, G; Kékesi, K; Soltesz, I | 1 |
| Doi, K; Matsunaga, T; Tsumoto, T | 1 |
| Mitchell, D; Sher, GD | 1 |
| Paoli, F; Pepeu, G; Spignoli, G | 1 |
| Massey, SC; Miller, RF | 1 |
| Girault, JA; Greengard, P; Halpain, S | 1 |
| Gonzales, RA; Woodward, JJ | 1 |
| Biesterfeldt, JP; Compton, RP; Cordi, AA; Hood, WF; Lanthorn, TH; Monahan, JB; Vazquez, MI; Wood, PL | 1 |
| Akerman, KE; Holopainen, I | 1 |
| Dudek, FE; Gribkoff, VK | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Fischbach, GD; O'Brien, RJ | 1 |
| Cherubini, E; King, AE; Nistri, A | 1 |
| Pastuszko, A; Wilson, DF; Yee, DK | 1 |
| Amano, T; Iijima, T; Kudo, Y; Ogura, A | 1 |
| de Graan, PN; Gispen, WH; Heemskerk, FM; Schrama, LH | 1 |
| Bear, MF; Kleinschmidt, A; Singer, W | 1 |
| Finkbeiner, S; Stevens, CF | 1 |
| Bossut, D; Frenk, H; Mayer, DJ | 1 |
| Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Vega, JL | 1 |
| Javitt, DC; Zukin, SR | 1 |
| Iino, M; Ozawa, S; Tsuzuki, K | 1 |
| Moran, J; Patel, AJ | 1 |
| Christensen, BN; O'Dell, TJ | 1 |
| Morris, RG | 1 |
| Buckley, KS; Collins, GG | 1 |
| Nelson, D; Pastuszko, A; Wilson, DF; Yee, DK | 2 |
| Chambers, G; Cottrell, JE; Kass, IS | 1 |
| Haberly, LB; Hoffman, WH | 1 |
| Dudek, S; Joly, M; Lynch, G; Muller, D; Schottler, F; Thibault, O | 1 |
| Boden, P; Hill, RG; McBain, CJ | 1 |
| Hablitz, JJ; Sutor, B | 2 |
| Barbeito, L; Cheramy, A; Girault, JA; Glowinski, J; Godeheu, G; Pittaluga, A | 1 |
| Bloch, V; Doyere, V; Laroche, S | 1 |
| DiLorenzo, M; Lynch, G; Staubli, U; Thibault, O | 1 |
| Girdlestone, D; Thomson, AM; West, DC | 1 |
| Hoehn, K; White, TD | 1 |
| Bagust, J; Kerkut, GA; Rakkah, NI | 1 |
| Schild, CP; Stein, PS | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| Benedetti, M; Pézzola, A; Sagratella, S; Scotti de Carolis, A | 1 |
| Miyamoto, T; Okada, Y | 1 |
| Matthies, H; Matthies, HK; Reymann, KG; Schulzeck, K | 1 |
| Jeftinija, S | 1 |
| Chandler, SH | 1 |
| Greer, JJ; Stein, RB | 1 |
| Greenberg, JH; Karp, A; Reivich, M; Uematsu, D | 1 |
| Krebs, JC; Trifunovic, R; Wirtshafter, D | 1 |
| Burgard, EC; Decker, G; Sarvey, JM | 1 |
| Choi, DW; Goldberg, MP; Monyer, H | 1 |
| Beart, PM; Manallack, DT; Sheehan, KA | 1 |
| Dingledine, R; Traynelis, SF | 1 |
| Costa, E; Danysz, W; Fadda, E; Wroblewski, JT | 1 |
| Jones, RS; Lambert, JD | 1 |
| Bode-Greuel, KM; Singer, W | 1 |
| Kamata, O; Katsuda, N; Nakanishi, H | 1 |
| Brugger, F; Olpe, HR; Pozza, MF; Steinmann, MW | 1 |
| Brodbelt, AR; Garthwaite, J | 1 |
| Lazarewicz, JW; Pluta, R; Salinska, E | 1 |
| Pierson, MG; Smith, KL; Swann, JW | 1 |
| Collingridge, GL; Davies, SN | 1 |
| Chapman, B; Miller, KD; Stryker, MP | 1 |
| Bear, MF; Gu, QA; Singer, W | 1 |
| Alesiani, M; Cherici, G; Galli, A; Mori, F; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Daw, N; Fox, K; Sato, H | 1 |
| Beart, PM; Lodge, D; Manallack, DT | 1 |
| Baldino, F; Gutnick, MJ; Wolfson, B | 1 |
| Gale, K; Maggio, R | 1 |
| Hauber, W; Schmidt, WJ | 1 |
| Akoev, GN; Andrianov, IuN; Bromm, B; Sabo, T; Sherman, NO | 1 |
| Ishihara, K; Katsuki, H; Satoh, M; Sugimura, M | 1 |
| Choi, DW; Hartley, DM | 1 |
| Chavkin, C; Swearengen, E | 2 |
| Evans, RH; Long, SK | 1 |
| Dun, NJ; Minota, S; Miyazaki, T; Read, HL; Wang, MY | 1 |
| Anderson, WW; Clark, S; Stasheff, SF; Wilson, WA | 1 |
| Clifford, DB; Todd, RD; Zorumski, CF | 1 |
| Caspary, DM; Faingold, CL; Hoffmann, WE | 1 |
| Bowe, MA; Martin, D; Nadler, JV | 1 |
| Fink, K; Göthert, M; Molderings, G; Schlicker, E | 1 |
| Aizenman, E; Rosenberg, PA | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| Czéh, G; Somjen, GG | 1 |
| Miyachi, E; Murakami, M | 1 |
| Evans, RH; Krijzer, F; Long, SK | 1 |
| Arslan, M; Plant, TM; Pohl, CR | 1 |
| De Bruin, LA; Korf, J; Schasfoort, EM | 1 |
| Collins, JF; Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Coan, EJ; Collingridge, GL | 2 |
| King, AE; Nistri, A; Rovira, C | 1 |
| Dale, N; Roberts, A | 1 |
| Gibson, BL; Reif-Lehrer, L | 1 |
| Colton, CA; Colton, JS | 1 |
| Gustafsson, B; Huang, YY; Wigström, H | 4 |
| Corradetti, R; King, AE; Nistri, A; Rovira, C; Sivilotti, L | 1 |
| Cunningham, JR; Neal, MJ | 1 |
| Lukasiewicz, PD; McReynolds, JS | 1 |
| Galvan, M; Slater, NT; Stelzer, A | 1 |
| Chmielewska, B; Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA | 1 |
| Lodge, D; Martin, D | 2 |
| Collingridge, GL; Herron, CE; Williamson, R | 1 |
| Hablitz, JJ | 1 |
| Henneberry, RC; Novelli, A | 1 |
| Martin, MR | 1 |
| Hablitz, JJ; Langmoen, IA | 1 |
| Cavalheiro, EA; Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA | 1 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| Carpenter, DO; Ffrench-Mullen, JM; Hori, N | 1 |
| Jahr, CE; Yoshioka, K | 1 |
| Kleer, E; Koek, W; Mudar, PJ; Woods, JH | 1 |
| Curry, K; Magnuson, DS; McLennan, H; Peet, MJ | 2 |
| Canning, HM; Leach, MJ; Marden, CM | 1 |
| Collins, KJ; Wheatley, PL | 1 |
| Collins, JF; Stone, TW | 1 |
| Gregersen, H; McLennan, H; Peet, MJ | 1 |
| Aimone, LD; Gebhart, GF | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Nelson, PG; Pun, RY; Westbrook, GL | 1 |
| Ashwood, TJ; Wheal, HV | 2 |
| Koek, W; Ornstein, P; Woods, JH | 2 |
| Andersson, P; Butcher, S; Hagberg, H; Hamberger, A; Lehmann, A; Sandberg, M | 1 |
| Koerner, JF; Marks, RL; Robinson, MB; Whittemore, ER | 1 |
| Stone, TW | 2 |
| Schmidt, WJ | 1 |
| Davies, J; Evans, RH; Herrling, PL; Jones, AW; Olverman, HJ; Pook, P; Watkins, JC | 1 |
| Baldino, F; Gutnick, MJ; Heinemann, U; Wolfson, B | 1 |
| Hamberger, A; Jacobson, I | 1 |
| Dragunow, M; Goddard, GV; Morimoto, K | 1 |
| Butcher, S; Hamberger, A; Jacobson, I | 1 |
| De Belleroche, JS; Gardiner, IM; Hamilton, MH; Herberg, LJ | 1 |
| Dingledine, R; King, GL | 1 |
| King, AE; Nistri, A | 1 |
| Rothman, SM | 1 |
| Davies, J; Miller, AJ; Sheardown, MJ | 1 |
| Freeman, JA; Langdon, RB | 1 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Johnson, KM; Jones, SM; Snell, LD | 2 |
| Ballanyi, K; Endres, W; Grafe, P; Serve, G | 1 |
| Gordon, FJ | 1 |
| Fagg, GE; Foster, AC | 1 |
| Anderson, WW; Swartzwelder, HS; Wilson, WA | 1 |
| Abraham, WC; Gustafsson, B; Huang, YY; Wigström, H | 1 |
| Bliss, TV; Errington, ML; Lynch, MA | 1 |
| Gustafsson, B; Wigström, H | 2 |
| Hamon, B; Heinemann, U; Stanton, PK | 1 |
| Ito, K; Izumi, Y; Kato, H; Kudo, Y; Miyakawa, H; Ogura, A | 1 |
| MacDonald, JF; Schneiderman, JH | 1 |
| Goddard, GV; Holmes, KH; Morimoto, K | 1 |
| Avoli, M; Olivier, A | 1 |
| Butcher, SP; Hagberg, H; Hamberger, A; Jacobson, I; Sandberg, M | 1 |
| Cline, HT; Constantine-Paton, M; Debski, EA | 1 |
| Brodin, L; Buchanan, JT; Dale, N; Grillner, S | 1 |
| Foster, AC; Wong, EH | 1 |
| Cherniack, NS; Mitra, J; Overholt, JL; Prabhakar, NR | 1 |
| Dingledine, R; Hynes, MA; King, GL | 1 |
| Crepel, F; Dupont, JL; Gardette, R | 1 |
| Drejer, J; Honoré, T; Schousboe, A | 1 |
| Clark, GD; Rothman, SM | 1 |
| Lees, GJ | 1 |
| Javitt, DC; Jotkowitz, A; Sircar, R; Zukin, SR | 1 |
| Addae, JI; Stone, TW | 1 |
| Cherniack, NS; Deal, EC; Haxhiu, MA; Norcia, MP; Strohl, KP; van Lunteren, E | 1 |
| Crunelli, V; Kelly, JS; Leresche, N; Pirchio, M | 1 |
| Krähling, H; Ruhland, M; Schmidt, WJ | 1 |
| de Carolis, AS; Frank, C; Sagratella, S | 1 |
| Burgoyne, RD; Cambray-Deakin, MA; Pearce, IA | 1 |
| Bockaert, J; Kemp, DE; Schmidt, BH; Sebben, M; Sladeczek, F; Weiss, S | 1 |
| Choi, DW; Peters, S | 1 |
| Raigorodsky, G; Urca, G | 2 |
| Choi, DW; Goldberg, MP; Pham, PC; Weiss, JH | 1 |
| Knöpfel, T | 1 |
| Barry, MJ; O'Donovan, MJ | 1 |
| Jones, RS | 2 |
| Choi, DW; Koh, JY; Peters, S | 1 |
| Hagiwara, S; Hirano, T | 1 |
| Jacobson, AE; Koek, W; Rice, KC; Woods, JH | 1 |
| Hagihara, K; Hata, Y; Sato, H; Tsumoto, T | 1 |
| Aram, JA; Lodge, D | 1 |
| Childs, AM; Evans, RH; Watkins, JC | 1 |
| Dewhurst, DG | 1 |
| Cain, DP; Desborough, KA; McKitrick, DJ | 1 |
| Kloog, Y; Nadler, V; Sokolovsky, M | 1 |
| Salt, TE | 1 |
| Krishtal, OA; Vrublevsky, SV | 1 |
| Roberts, A; Sillar, KT | 1 |
| Casella, C; Masetto, S; Prigioni, I; Russo, G | 1 |
| Larson, J; Lynch, G | 1 |
| Caudle, RM; Isaac, L | 2 |
| Krishtal, OA; Smirnov, SV | 1 |
| Davis, M; Spiera, RF | 1 |
| Burton, NR; Smith, DA; Stone, TW | 1 |
| Beart, PM; Headley, PM; Nicolopoulos, LS; West, DC | 1 |
| Choi, DW; Coulter, DA; Prince, DA; Wong, BY | 1 |
| Chang, HS; Kano, M; Kato, M | 1 |
| Coopersmith, R; Cotman, CW; Harris, EW; Leon, M; Lincoln, J | 1 |
| Ambar, I; Kloog, Y; Sokolovsky, M | 1 |
| Lason, W; McGinty, JF; Simpson, JN | 1 |
| Kihara, M; Kubo, T | 1 |
| Bockaert, J; Pin, JP; Van-Vliet, BJ | 1 |
| Heinemann, U; Jones, RS | 1 |
| Connick, JH; Stone, TW | 2 |
| Carter, CJ; L'Heureux, R; Scatton, B | 1 |
| Aitken, PG; Balestrino, M; Somjen, GG | 1 |
| Consolo, S; Forloni, G; Ladinsky, H; Palazzi, E | 1 |
| Pastuszko, A; Wilson, DF | 1 |
| Abraham, WC; Kairiss, EW | 1 |
| Nishizaki, T; Okada, Y | 1 |
| Collingridge, GL; Herron, CE; Lester, RA | 2 |
| Lopes da Silva, FH; Melchers, BP; Pennartz, CM; Wadman, WJ | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Forsythe, ID; Westbrook, GL | 1 |
| Fletcher, EJ; Lodge, D | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| Gean, PW; Shinnick-Gallagher, P | 1 |
| Costa, E; Danysz, W; Wroblewski, JT | 1 |
| Collins, GG; Howlett, SJ | 1 |
| Jones, AW; Olverman, HJ; Watkins, JC | 1 |
| Jones, AW; Mewett, KN; Olverman, HJ; Watkins, JC | 1 |
| King, AE; Thompson, SW; Urban, L; Woolf, CJ | 1 |
| Avoli, M; Hwa, GG; Tancredi, V | 1 |
| Benedetti, M; Sagratella, S; Scotti de Carolis, AS | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Dieringer, N; Knöpfel, T | 1 |
| Mayer, ML; Vyklický, L; Westbrook, GL | 1 |
| Baughman, RW; Jones, KA | 1 |
| Trifunovic, R; Wirtshafter, D | 1 |
| Ben-Ari, Y; Cherubini, E; Neuman, R | 1 |
| Fagni, L; Hugon, M; Zinebi, F | 1 |
| Aihara, H; Okuyama, S | 1 |
| Gasser, T; Reddington, M; Schubert, P | 1 |
| Aniksztejn, L; Ben-Ari, Y; Charriaut-Marlangue, C; Roisin, MP | 1 |
| Alford, ST; Coan, EJ; Collingridge, GL; Davies, SN; Lester, RA | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Lynch, G; Muller, D | 2 |
| Desborough, KA; Leung, LW | 1 |
| Heinemann, U; Jones, RS; Mody, I; Stanton, PK | 1 |
| Burton, NR; Smith, DA; Stone, TW; Williams, TL | 2 |
| Coleman, PA; Miller, RF | 1 |
| Joly, M; Lynch, G; Muller, D | 1 |
| Lovinger, DM; Weight, FF | 1 |
| Beart, PM; Davies, SN; Jones, MG; Lodge, D; Manallack, DT; Millar, J; Ornstein, PL; Verberne, AJ; Young, N | 1 |
| Felder, RB; Miller, BD | 1 |
| Linden, DJ; Routtenberg, A; Sheu, FS; Wong, KL | 1 |
| Bliss, TV; Dolphin, AC; Errington, ML; Fazeli, MS | 1 |
| Morris, RG; Rawlins, JN; Tonkiss, J | 1 |
| Lauritzen, M; Nicholson, C; Okada, Y; Rice, ME | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Baudry, M; Jung, MW; Larson, J; Lynch, G; Oliver, M; Seubert, P | 1 |
| Benveniste, H; Diemer, NH; Hansen, AJ; Jørgensen, MB | 1 |
| Kita, H; Kitai, ST; Nakanishi, H | 1 |
| Ben-Ari, Y; Corradetti, R; Gaïarsa, JL | 1 |
| Armstrong-James, M; Fox, K | 1 |
| Ben-Ari, Y; Gho, M | 1 |
| Cherubini, E; North, RA; Williams, JT | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 1 |
| Collins, JF; Curry, K; Labruyere, J; Olney, JW | 1 |
| McLennan, H | 3 |
| Collins, JF; Cunningham, JR; James, TA; Joseph, M; Neal, MJ | 1 |
| Dawbarn, D; Pycock, CJ | 1 |
| Ikeda, H; Sheardown, MJ | 2 |
| Collins, JF; Foster, GA; Roberts, PJ; Sharif, NA | 1 |
| Collins, GG | 1 |
| Curtis, DR; Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Leah, JD; Peet, MJ | 1 |
| Close, JM; Loewy, AD; Neil, JJ | 1 |
| Collingridge, GL; Crunelli, V; Forda, S; Kelly, JS | 1 |
| Lehmann, J; Scatton, B | 1 |
| Nair, NP; Pilapil, C; Richard, JW; Wood, PL | 1 |
| Collins, JF; Parks, DA; Schwarcz, R | 1 |
| Davies, J; Watkins, JC | 2 |
| Eng, P; Hösli, E; Hösli, L; Lehmann, R | 1 |
| Collingridge, GL; Kehl, SJ; McLennan, H | 2 |
| Cotman, CW; Ganong, AH | 1 |
| Crunelli, V; Forda, S; Kelly, JS | 1 |
| Collins, JF; Croucher, MJ; Curry, K; Czuczwar, SJ; Joseph, M; Meldrum, BS; Stone, TW | 1 |
| Bradford, HF; Collins, JF; Peterson, DW | 2 |
| Badman, G; Collins, JF; Croucher, MJ; Meldrum, BS | 1 |
| Coyle, JT; Ferkany, JW; Lehmann, J; Schaefer, P | 1 |
| Goh, JW; Pandanaboina, MM; Sastry, BR | 1 |
| Joëls, M; Urban, IJ | 1 |
| Dvorak, DR; Morgan, IG | 1 |
| Croucher, MJ; Jones, AW; Meldrum, BS; Watkins, JC | 1 |
| Czuczwar, SJ; Kleinrok, Z; Schwarz, M; Turski, L; Turski, WA | 1 |
| Cahusac, PM; Evans, RH; Hill, RG; Rodriquez, RE; Smith, DA | 1 |
| Bolz, J; Thier, P; Wässle, H | 1 |
| Mayer, ML; Westbrook, GL | 1 |
| King, AE; Wheal, HV | 1 |
| MacDonald, JF; Morris, ME | 1 |
| Cotman, CW; Monaghan, DT; Olverman, HJ; Watkins, JC; Yao, D | 1 |
| Cotman, CW; Ganong, AH; Harris, EW | 1 |
| Buchhalter, JR; Djali, S; Robinson, MB | 1 |
| Akhondzadeh, S; Stone, TW | 1 |
| Chung, SH; Premkumar, L | 1 |
| Bennett, JP; Richard, MG | 1 |
| Feuerstein, TJ | 1 |
| Kato, N | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M | 1 |
| Laber, B; Lindell, SD; Pohlenz, HD | 1 |
| Xue, GP; Zhang, DS; Zhang, L; Zhang, SS | 1 |
| Fukunaga, K; Miyamoto, E; Muller, D; Stoppini, L | 1 |
| Ben-Ari, Y; Congar, P; Khazipov, R | 1 |
| Elaagouby, A; Gervais, R | 1 |
| Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
| Liesi, P; Wright, JM | 1 |
| Banczerowski-Pelyhe, I; Csúcs, G; Tarnawa, I; Világi, I | 1 |
| Chieng, B; Christie, MD | 1 |
| Bartlett, E; Oliver, DL; Peruzzi, D; Smith, PH | 1 |
| Furukawa, K; Holtsberg, FW; Keller, JN; Mattson, MP; Steiner, MR; Steiner, SM | 1 |
| Kawabe, A; Maruoka, Y; Nakamura, M; Ohno, Y; Ohtani, K; Sakamoto, H; Tamamura, C; Tanaka, H; Yasuda, H | 1 |
| Gatherer, M; Sundstrom, LE | 1 |
| Buerkle, H; Khan, IM; Taylor, P; Yaksh, TL | 1 |
| Behrens, MM; Díaz-Guerra, M; García-Gallo, M; Renart, J | 1 |
| Cash, SS; Denk, W; Majewska, A; Yuste, R | 1 |
| Diao, L; Dunwiddie, TV; Finger, TE; Smeraski, CA | 1 |
| Goto, F; Ishizaki, K; Karasawa, S; Nara, T; Obata, H; Sasaki, M | 1 |
| Arai, Y; Kamino, K; Mochida, H; Momose-Sato, Y; Sato, K; Yazawa, I | 1 |
| Delgado-Lezama, R; Hounsgaard, J; Perrier, JF | 1 |
| Mele, A; Oliverio, A; Roullet, P; Sargolini, F | 1 |
| Cowan, AI; Field, AC; Redman, SJ; Stricker, C | 1 |
| Foldes, JK; Hauser, KF; Turbek, CS | 1 |
| Kouznetsova, M; Nistri, A | 1 |
| Bennett, AD; Everhart, AW; Hulsebosch, CE | 1 |
| Cohen, I; Miles, R | 1 |
| Kötter, R; Luhmann, HJ; Staiger, JF; Zilles, K | 1 |
| Helmstetter, FJ; Tershner, SA | 1 |
| Aoyagi, A; Kaneko, T; Kikusui, T | 1 |
| Bertram, EH; Mangan, PS; Scott, CA; Williamson, JM | 1 |
| Birkenfeld, K; Palve, M; Spiess, J; Stiedl, O | 1 |
| Empson, RM; Gee, VJ; Newberry, NR; Sheardown, MJ | 1 |
| Gorji, A; Köhling, R; Scheller, D; Speckmann, EJ; Straub, H; Tegtmeier, F | 1 |
| Gyermek, L; Hanaoka, K; Kawasaki-Yatsugi, S; Lee, C; Nishiyama, T; Yamaguchi, T | 1 |
| de Groat, WC; Kawatani, M; Miura, A | 1 |
| Aihara, H; Kondoh, T; Nishizaki, T; Tamaki, N | 1 |
| Bhave, G; Carlton, SM; Gereau , RW; Karim, F | 1 |
| Kleschevnikov, AM; Routtenberg, A | 1 |
| Castro, SL; Zigmond, MJ | 1 |
| Bohn, I; Giertler, C; Hauber, W | 2 |
| Guo, Y; Sánchez, C; Udin, SB | 1 |
| Boettiger, CA; Doupe, AJ | 1 |
| Akaike, N; Katsurabayashi, S; Kiyosawa, A; Pang, ZP | 1 |
| Kazuta, Y; Kohsaka, S; Kudo, Y; Matsuda, A; Mishina, M; Nakajima-Iijima, S; Nakamura, T; Shuto, S; Uchino, S; Watanabe, W | 1 |
| Hu, JY; Zhao, ZQ | 1 |
| Abe, H; Iwasaki, T | 1 |
| Colicos, MA; Collins, BE; Goda, Y; Sailor, MJ | 1 |
| Wang, GD; Zhuo, M | 1 |
| Blitz, DM; Chen, C; Regehr, WG | 1 |
| Lei, S; McBain, CJ | 1 |
| Hess, G; Kossut, M; Urban, J | 1 |
| Glick, SD; Maisonneuve, IM; Shoblock, JR; Sullivan, EB | 1 |
| Hama, A; Sagen, J; Woon Lee, J | 1 |
| Iino, M; Kakegawa, W; Ozawa, S; Tsuzuki, K | 1 |
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| Jacobs, KM; Jin, X; Povlishock, JT; Vascak, M | 1 |
| Frazier, CJ; Krause, EG; Pati, D | 1 |
| Goodman, J; Packard, MG; Ressler, RL | 1 |
| Ebrahimi-Ghiri, M; Khakpai, F; Nasehi, M; Ostadi, E; Zarrindast, MR | 1 |
| Copeland, CS; Neale, SA; Nisenbaum, E; Parri, HR; Salt, TE; Sims, RE; Wall, TM | 1 |
| Davies, DA; Greba, Q; Howland, JG; Hurtubise, JL | 1 |
| Kato, T; Kawano, T; Sato, H; Toyoda, H; Yin, DX | 1 |
| Enomoto, A; Hamada, S; Ishihama, K; Kogo, M; Seki, S; Tanaka, S; Yamanishi, T | 1 |
| Gu, K; Jiang, B; Li, Y; Ma, P; Ma, X; Song, T; Wang, C; Yang, Y; Zhao, J | 1 |
| Li, Y; Liu, X; Patel, KP; Zheng, H | 1 |
| Momose-Sato, Y; Sato, K | 1 |
| Blümcke, I; Groemer, TW; Hackenbracht, J; Jablonski, J; Kiese, K; Kobow, K; Kornhuber, J; Wrosch, JK | 1 |
| Feng, SF; Huang, Y; Liu, G; Shi, TY; Wei, MX; Wu, HT; Zhang, YX; Zhou, WX | 1 |
| Collingridge, GL; Jia, Z; Leung, C; Liu, A; Meng, Y; Park, P; Qi, J; Xia, S; Xie, W; Zhou, Z | 1 |
| Macklis, JD; Markopoulos, F; Murthy, VN; Padmanabhan, H; Wheeler, AP; Wuttke, TV | 1 |
| Kucharz, K; Lauritzen, M | 1 |
| Kelly, CJ; Martina, M | 1 |
| Barragan, EV; Crestani, AP; Gray, JA; Krueger, JN; Nakazawa, Y; Nemes, SE; Quillfeldt, JA; Wiltgen, BJ | 1 |
| Antic, SD; McKimm, EJ; Milosevic, MM; Singh, MB; White, JA | 1 |
| Bhandiwad, AA; Raible, DW; Rubel, EW; Sisneros, JA | 1 |
| Hisatsune, A; Katsuki, H; Kurauchi, Y; Noma, K; Seki, T | 1 |
| Kozyrev, SA; Nikitin, VP; Solntseva, SV | 1 |
| Khaliq, ZM; Philippart, F | 1 |
| Alaei, H; Eidi, A; Keramatian, A; Radahmadi, M | 1 |
| Bing, YH; Chu, CP; Cui, BR; Cui, LN; Li, BX; Qiu, DL; Zhang, GJ; Zhang, XY | 1 |
| Kozyrev, SA; Nikitin, PV; Nikitin, VP; Solntseva, SV | 1 |
2 review(s) available for 2-amino-5-phosphonovalerate and valine
| Article | Year |
|---|---|
On the excitatory post-synaptic potential evoked by stimulation of the optic tract in the rat lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aminobutyrates; Animals; Aspartic Acid; Calcium; Dipeptides; Glutamates; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Optic Nerve; Rats; Rats, Inbred Strains; Synapses; Thalamic Nuclei; Valine | 1987 |
Modulation of allopregnanolone on excitatory transmitters release from single glutamatergic terminal.
Topics: Animals; Animals, Newborn; Bicuculline; Biophysics; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutamic Acid; Muscimol; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnanolone; Presynaptic Terminals; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Tetraethylammonium; Valine | 2013 |
933 other study(ies) available for 2-amino-5-phosphonovalerate and valine
| Article | Year |
|---|---|
Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors.
Topics: Ammonia; Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1992 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
N-methyl-D-aspartate receptor antagonism alters substance P and met5-enkephalin biosynthesis in neurons of the rat striatum.
Topics: Animals; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Male; N-Methylaspartate; Neurons; Piperazines; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P; Tachykinins; Valine | 1992 |
N-methyl-D-aspartate and vasopressin activate distinct voltage-dependent inward currents in facial motoneurones.
Topics: Animals; Arginine Vasopressin; Brain Stem; Dizocilpine Maleate; Electric Conductivity; Evoked Potentials; Facial Nerve; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Valine | 1992 |
Potentiation of cyanide neurotoxicity by blockade of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Diazoxide; Drug Synergism; Glyburide; Hippocampus; Kinetics; L-Lactate Dehydrogenase; Neurons; Neurotoxins; Potassium Channels; Sodium Cyanide; Valine | 1992 |
Studies of the role of the N-methyl-D-aspartate (NMDA) receptor in the hypothalamic control of prolactin secretion.
Topics: Animals; Hypothalamus; Male; N-Methylaspartate; Prolactin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety, Separation; Behavior, Animal; Buspirone; Diazepam; Dioxins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Indoles; Kynurenic Acid; Maternal Deprivation; Mephenesin; Piperidines; Quinolizines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Valine; Vocalization, Animal | 1991 |
Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors.
Topics: Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Glutamates; Glutamic Acid; In Vitro Techniques; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Thalamus; Valine | 1991 |
Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy.
Topics: Animals; Catalepsy; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haloperidol; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1991 |
CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Binding, Competitive; Electrophysiology; Electroshock; Glutamates; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1990 |
Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1990 |
Effect of L-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies.
Topics: Animals; Corpus Striatum; Dialysis; Dopamine; Glutamates; Glutamic Acid; Kinetics; Male; Membrane Potentials; Microelectrodes; Perfusion; Potassium; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Electrophysiology; Hippocampus; Iontophoresis; Male; Oxadiazoles; Piperazines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Substantia Nigra; Valine | 1990 |
Sleep-promoting action of excitatory amino acid antagonists: a different role for thalamic NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sleep; Thalamic Nuclei; Valine | 1990 |
Actions of excitatory amino acid antagonists on synaptic inputs to the rat medial vestibular nucleus: an electrophysiological study in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Male; Neural Pathways; Neurons, Afferent; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine; Vestibular Nuclei | 1990 |
N-methyl-D-aspartate receptors mediate responses of rat dorsal horn neurones to hindlimb ischemia.
Topics: Animals; Anterior Horn Cells; Hindlimb; Injections, Spinal; Ischemia; Ketamine; Male; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1990 |
Oxiracetam and D-pyroglutamic acid antagonize a disruption of passive avoidance behaviour induced by the N-methyl-D-aspartate receptor antagonist 2-amino-5-phosphonovalerate.
Topics: Animals; Avoidance Learning; Injections, Intraventricular; Male; Motor Activity; Pyrrolidines; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
N-methyl-D-aspartate receptors of ganglion cells in rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Valine | 1990 |
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.
Topics: Animals; Aspartic Acid; Calcineurin; Calmodulin-Binding Proteins; Colforsin; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Activation; N-Methylaspartate; Nerve Tissue Proteins; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphothreonine; Protein Kinases; Protein Phosphatase 1; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
Ethanol inhibits N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat cortical slices.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Culture Techniques; Ethanol; Glycine; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Valine | 1990 |
Differential modulation of the associated glycine recognition site by competitive N-methyl-D-aspartate receptor antagonists.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Glycine; Male; N-Methylaspartate; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
Efflux of 45calcium from cultured primary astrocytes: effects of glutamate receptor agonists and antagonists.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Calcium Radioisotopes; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Valine | 1990 |
Effects of excitatory amino acid antagonists on synaptic responses of supraoptic neurons in slices of rat hypothalamus.
Topics: Animals; Bicuculline; Dipeptides; Female; In Vitro Techniques; Kynurenic Acid; Male; Membrane Potentials; Neurons; Rats; Supraoptic Nucleus; Synapses; Valine | 1990 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1986 |
A study of amino acid-activated currents recorded from frog motoneurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neural Conduction; Oxadiazoles; Quisqualic Acid; Rana temporaria; Valine | 1987 |
Regulation of calcium uptake in synaptosomes from rat brain by DL-2-amino-5-phosphonovaleric acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Ion Channels; Kinetics; Male; Membrane Potentials; Oxygen Consumption; Rats; Rats, Inbred Strains; Ruthenium Red; Sodium; Synaptosomes; Valine | 1987 |
Optical monitoring of excitatory synaptic activity between cultured hippocampal neurons by a multi-site Ca2+ fluorometry.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Cytophotometry; Hippocampus; Ion Channels; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 1987 |
4-Aminopyridine inhibits synaptosomal plasma membrane protein phosphorylation in vitro: effect of the selective NMDA-antagonist 2-amino-5-phosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Hippocampus; In Vitro Techniques; Ion Channels; Male; Membrane Proteins; Molecular Weight; Nerve Tissue Proteins; Phosphoproteins; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Valine | 1987 |
Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cats; Corpus Striatum; Ion Channels; Neurons; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Synapses; Valine; Vision, Ocular | 1987 |
Applications of quantitative measurements for assessing glutamate neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Glycine; Hippocampus; In Vitro Techniques; Ion Channels; Magnesium; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Is substance P a primary afferent neurotransmitter for nociceptive input? IV. 2-Amino-5-phosphonovalerate (APV) and [D-Pro2,D-Trp7,9]-substance P exert different effects on behaviors induced by intrathecal substance P, strychnine and kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P; Valine | 1988 |
Systemic approaches to modifying quinolinic acid striatal lesions in rats.
Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine | 1988 |
Excitatory transmitters, ventral root potentials and [K+]o in the isolated frog leg-spinal cord preparation.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; In Vitro Techniques; Kynurenic Acid; Pain; Physical Stimulation; Potassium; Rana pipiens; Spinal Nerve Roots; Substance P; Valine | 1988 |
Biexponential kinetics of [3H]MK-801 binding: evidence for access to closed and open N-methyl-D-aspartate receptor channels.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glycine; In Vitro Techniques; Ion Channels; Kinetics; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Synaptosomes; Valine | 1989 |
Ion channels activated by quinolinic acid in cultured rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Hippocampus; Ion Channels; Magnesium; Membrane Potentials; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Stimulation of the N-methyl-D-aspartate receptor promotes the biochemical differentiation of cerebellar granule neurons and not astrocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Cell Differentiation; Cells, Cultured; Cerebellum; Glutaminase; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA; Valine | 1989 |
Horizontal cells isolated from catfish retina contain two types of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Cations, Divalent; Cell Membrane Permeability; Cells, Cultured; Concanavalin A; Convulsants; Glutamates; Ibotenic Acid; Ictaluridae; Ion Channels; Kainic Acid; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Valine; Zinc | 1989 |
Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5.
Topics: Animals; Behavior, Animal; Discrimination Learning; Learning; Male; Motor Activity; Neuronal Plasticity; Rats; Rats, Inbred Strains; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retention, Psychology; Sensation; Space Perception; Synapses; Valine; Visual Perception | 1989 |
Antagonism of monosynaptic excitations in the mouse olfactory cortex slice by 6,7-dinitroquinoxaline-2,3-dione.
Topics: Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Male; Mice; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Reflex, Monosynaptic; Synapses; Synaptic Transmission; Valine | 1989 |
Effects of DL-2-amino-5-phosphonovalerate on metabolism of catecholamines in synaptosomes from rat brain.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catecholamines; Dopamine; Male; Monoamine Oxidase; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Valine; Veratridine | 1989 |
The N-methyl-D-aspartate antagonists aminophosphonovaleric acid and MK-801 reduce anoxic damage to dentate granule and CA1 pyramidal cells in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Male; N-Methylaspartate; Neurotoxins; Pyramidal Tracts; Rats; Rats, Inbred Strains; Valine | 1989 |
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine | 1989 |
Long-lasting physiological effects of bath applied N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Spermine; Time Factors; Valine | 1989 |
Rat hippocampal slices 'in vitro' display spontaneous epileptiform activity following long-term organotypic culture.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Culture Techniques; Epilepsy; Hippocampus; Magnesium; Membrane Potentials; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Time Factors; Valine | 1989 |
Long-term potentiation in frontal cortex: role of NMDA-modulated polysynaptic excitatory pathways.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Frontal Lobe; In Vitro Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Valine | 1989 |
Activation of the bilateral corticostriatal glutamatergic projection by infusion of GABA into thalamic motor nuclei in the cat: an in vivo release study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Injections; Male; Synaptic Transmission; Thalamic Nuclei; Valine | 1989 |
Linear relation between the magnitude of long-term potentiation in the dentate gyrus and associative learning in the rat. A demonstration using commissural inhibition and local infusion of an N-methyl-D-aspartate receptor antagonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Behavior, Animal; Electric Stimulation; Electrophysiology; Hippocampus; Injections; Learning; Male; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Valine | 1989 |
Antagonism of NMDA receptors impairs acquisition but not retention of olfactory memory.
Topics: 2-Amino-5-phosphonovalerate; Animals; Central Nervous System; Discrimination Learning; Injections, Intraventricular; Memory; Odorants; Olfactory Pathways; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
A local circuit neocortical synapse that operates via both NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dipeptides; Electric Stimulation; Female; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neural Conduction; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1989 |
Evoked release of endogenous adenosine from rat cortical slices by K+ and glutamate.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Cerebral Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Potassium; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Differential sensitivity of dorsal and ventral root activity to magnesium and 2-amino-5-phosphonovalerate (APV) in an isolated mammalian spinal cord preparation.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cricetinae; Electric Stimulation; In Vitro Techniques; Magnesium; Spinal Nerve Roots; Valine | 1989 |
N-methyl-D-aspartate antagonist applied to the spinal cord hindlimb enlargement reduces the amplitude of flexion reflex in the turtle.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hindlimb; Motor Neurons; Neurons, Afferent; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Spinal Cord; Turtles; Valine | 1989 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Behavioural and electroencephalographic effects of excitatory amino acid antagonists and sigma opiate/phencyclidine-like compounds in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Male; Phencyclidine; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Valine | 1989 |
Formation of long-term potentiation in superior colliculus slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Guinea Pigs; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Time Factors; Valine | 1989 |
N-methyl-D-aspartate receptor activation is required for the induction of both early and late phases of long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Valine | 1989 |
Excitatory transmission in the dorsal horn is in part mediated through APV-sensitive NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; In Vitro Techniques; Magnesium; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission; Valine | 1989 |
Evidence for excitatory amino acid transmission between mesencephalic nucleus of V afferents and jaw-closer motoneurons in the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Guinea Pigs; Kynurenic Acid; Male; Masseter Muscle; Mesencephalon; Motor Neurons; N-Methylaspartate; Neurotransmitter Agents; Synapses; Synaptic Transmission; Trigeminal Nuclei; Valine | 1989 |
Patterns of gamma-motoneuron activity in the external intercostal muscles of the cat during respiration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electromyography; Motor Neurons; Respiration; Respiratory Muscles; Valine | 1989 |
Cytosolic free calcium and NAD/NADH redox state in the cat cortex during in vivo activation of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cats; Cerebral Cortex; Cytosol; Fluorescent Dyes; In Vitro Techniques; Male; N-Methylaspartate; NAD; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Behavioral and biochemical evidence for a functional role of excitatory amino acids in the median raphe nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Dopamine; Dose-Response Relationship, Drug; Kynurenic Acid; Male; Motor Activity; Raphe Nuclei; Rats; Rats, Inbred Strains; Valine | 1989 |
NMDA receptor antagonists block norepinephrine-induced long-lasting potentiation and long-term potentiation in rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Glucose deprivation neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; Glucose; L-Lactate Dehydrogenase; Mice; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Comparison of the properties of [3H]-D-2-amino-5-phosphonopentanoic acid and [3H]-DL-2-amino-7-phosphonoheptanoic acid binding to homogenates of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; In Vitro Techniques; Ligands; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Salts; Tritium; Valine | 1989 |
EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Modification of potassium-induced interictal bursts and electrographic seizures by divalent cations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Hippocampus; In Vitro Techniques; Magnesium; Potassium; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1989 |
Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the N-methyl-D-aspartate-sensitive glutamate receptor domain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding Sites; Binding, Competitive; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Kynurenic Acid; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine; Subcellular Fractions; Valine | 1989 |
Activation of N-methyl-D-aspartate receptors contributes to the EPSP at perforant path synapses in the rat dentate gyrus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Evoked Potentials; Hippocampus; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
The development of N-methyl-D-aspartate receptors in cat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Binding, Competitive; Cats; Glutamates; Glutamic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex | 1989 |
2-amino-5-phosphonovaleric acid blocks induction of an epileptiform discharge following a brief hypoxic episode in the hippocampal slices prepared from dietary Mg-deficient mouse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Diet; Epilepsy; Hippocampus; Hypoxia; In Vitro Techniques; Magnesium Deficiency; Male; Mice; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Valine | 1989 |
Excitatory amino acid receptors in rat locus coeruleus. An extracellular in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Locus Coeruleus; Magnesium; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1989 |
Synaptic activation of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors in the mossy fibre pathway in adult and immature rat cerebellar slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Cerebellum; Female; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Participation of NMDA-receptors in ischemic changes of calcium homeostasis in rabbit brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Calcium; Female; Hippocampus; Homeostasis; Ischemic Attack, Transient; Male; Nimodipine; Rabbits; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Valine | 1989 |
A slow NMDA-mediated synaptic potential underlies seizures originating from midbrain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; In Vitro Techniques; Inferior Colliculi; N-Methylaspartate; Picrotoxin; Rats; Seizures; Valine | 1989 |
Role of excitatory amino acid receptors in synaptic transmission in area CA1 of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Valine | 1989 |
Visual responses in adult cat visual cortex depend on N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cats; Electric Conductivity; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Perception | 1989 |
Blockade of NMDA-receptors prevents ocularity changes in kitten visual cortex after reversed monocular deprivation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Cats; Cattle; Evoked Potentials, Visual; Neuronal Plasticity; Ocular Physiological Phenomena; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex | 1989 |
Glycine and kynurenate modulate the glutamate receptors in the myenteric plexus and in cortical membranes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Cerebral Cortex; Glycine; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Myenteric Plexus; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
The location and function of NMDA receptors in cat and kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Cats; Dose-Response Relationship, Drug; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tissue Distribution; Valine; Visual Cortex | 1989 |
Subchronic administration of MK-801 in the rat decreases cortical binding of [3H]D-AP5, suggesting down-regulation of the cortical N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Ataxia; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Tolerance; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Synchronized neuronal activities in neocortical explant cultures.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Cerebral Cortex; Magnesium; Membrane Potentials; Neural Conduction; Organ Culture Techniques; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1989 |
Seizures evoked from area tempestas are subject to control by GABA and glutamate receptors in substantia nigra.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Glutamates; Male; Morphine; Muscimol; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Seizures; Substantia Nigra; Valine | 1989 |
Effects of intrastriatal blockade of glutamatergic transmission on the acquisition of T-maze and radial maze tasks.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Glutamates; Glutamic Acid; Male; Psychomotor Performance; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1989 |
[Analysis of the effect of quisqualate, N-methyl-D- aspartate and several blockers of amino acid receptors on synaptic transmission in the ampullae of Lorenzini].
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Electric Fish; Evoked Potentials; Magnesium; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sensory Receptor Cells; Skates, Fish; Synapses; Synaptic Transmission; Valine | 1989 |
Idebenone and vinpocetine augment long-term potentiation in hippocampal slices in the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Benzoquinones; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Pyramidal Tracts; Quinones; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Ubiquinone; Valine; Vinca Alkaloids | 1989 |
Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1989 |
Comparison of opioid and GABA receptor control of excitability and membrane conductance in hippocampal CA1 pyramidal cells in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Morphine Derivatives; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Valine | 1989 |
Primary afferent depolarization in the rat spinal cord is mediated by pathways utilising NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Ganglia, Spinal; In Vitro Techniques; Kynurenic Acid; Neurons, Afferent; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Glycine potentiates NMDA responses in rat hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glycine; Hippocampus; Humans; N-Methylaspartate; Rats; Valine | 1989 |
NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1989 |
Complex responses activated by ibotenate in postnatal rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cells, Cultured; Hippocampus; Ibotenic Acid; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Effects of excitant amino acids on acoustic responses of inferior colliculus neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Inferior Colliculi; N-Methylaspartate; Parasympathomimetics; Rats; Rats, Inbred Strains; Valine | 1989 |
A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Female; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1989 |
N-methyl-D-aspartate (NMDA) receptor-mediated stimulation of noradrenaline release, but not release of other neurotransmitters, in the rat brain cortex: receptor location, characterization and desensitization.
Topics: 2-Amino-5-phosphonovalerate; 5-Hydroxytryptophan; Animals; Cerebral Cortex; Choline; Glutamates; Hippocampus; Male; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes; Valine | 1989 |
Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Electrophysiology; Glutamates; Glycine; Hippocampus; Histocytochemistry; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
Spontaneous activity induced in isolated mouse spinal cord by high extracellular calcium and by low extracellular magnesium.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Calcium; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Mice; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1989 |
Coexistence of NMDA and non-NMDA receptors on turtle horizontal cells revealed using isolated retina preparations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Visual; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles; Valine | 1989 |
Effects of depressant amino acids and antagonists on an in vitro spinal cord preparation from the adult rat.
Topics: Action Potentials; Amino Acids; Animals; Bicuculline; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; Picrotoxin; Piperazines; Rats; Spinal Cord; Strychnine; Synapses; Taurine; Valine | 1989 |
DL-2-amino-5-phosphonopentanoic acid, a specific N-methyl-D-aspartic acid receptor antagonist, suppresses pulsatile LH release in the rat.
Topics: Animals; Aspartic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Mild stress stimulates rat hippocampal glucose utilization transiently via NMDA receptors, as assessed by lactography.
Topics: Animals; Extracellular Space; Glucose; Hippocampus; Lactates; Lactic Acid; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Restraint, Physical; Stress, Physiological; Valine | 1988 |
Muscle relaxant action of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Spasticity; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
Magnesium ions block an N-methyl-D-aspartate receptor-mediated component of synaptic transmission in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; In Vitro Techniques; Magnesium; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Valine | 1985 |
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine | 1985 |
Dual-component amino-acid-mediated synaptic potentials: excitatory drive for swimming in Xenopus embryos.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Evoked Potentials; Interneurons; Motor Neurons; Pipecolic Acids; Spinal Cord; Swimming; Synapses; Synaptic Transmission; Time Factors; Valine; Xenopus | 1985 |
Mg2+ reduces N-methyl-D-aspartate neurotoxicity in embryonic chick neural retina in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Animals; Aspartic Acid; Chick Embryo; In Vitro Techniques; Magnesium; N-Methylaspartate; Retina; Valine | 1985 |
Blockade of hyperbaric oxygen induced seizures by excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Anticonvulsants; Glutamates; Hyperbaric Oxygenation; Mice; Proline; Seizures; Valine | 1985 |
A synaptic potential following single volleys in the hippocampal CA1 region possibly involved in the induction of long-lasting potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; Picrotoxin; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
Pharmacological characterization of D-aminophosphonovaleric acid antagonism of amino acid and synaptically evoked excitations on frog motoneurones in vitro: an intracellular study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Microelectrodes; Motor Neurons; Rana temporaria; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 1985 |
Effect of excitatory amino acids and analogues on [3H]acetylcholine release from amacrine cells of the rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cholinergic Fibers; Electroretinography; N-Methylaspartate; Neurons; Pipecolic Acids; Rabbits; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Valine | 1985 |
Synaptic transmission at N-methyl-D-aspartate receptors in the proximal retina of the mudpuppy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; In Vitro Techniques; N-Methylaspartate; Necturus; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Valine | 1985 |
Kindling-like stimulus patterns induce epileptiform discharges in the guinea pig in vitro hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Membrane Potentials; Neural Pathways; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Valine | 1985 |
Modification of the anticonvulsant activity of 2-amino-5-phosphonovalerate by agents affecting different neurotransmitter systems.
Topics: 2-Amino-5-phosphonovalerate; 4-Butyrolactone; Animals; Anticonvulsants; Atropine; Baclofen; Brain; Drug Interactions; Male; Mice; Muscimol; Neurotransmitter Agents; Sodium Oxybate; Synaptic Transmission; Valine | 1985 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
A selective N-methyl-D-aspartate antagonist depresses epileptiform activity in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Epilepsy; Evoked Potentials; Female; Folic Acid Antagonists; Hippocampus; In Vitro Techniques; Magnesium; Pentylenetetrazole; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
Action of excitatory amino acids and their antagonists on hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; Iontophoresis; Manganese; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Tetrodotoxin; Valine | 1985 |
Veratrine- and glutamate-stimulated cGMP production in cultured rat neurons is differentially inhibited by imipramine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebellum; Cyclic GMP; Cytoplasmic Granules; Glutamates; Glutamic Acid; Imipramine; Neurons; Rats; Tetrodotoxin; Valine; Veratrine | 1985 |
Evidence for an excitatory amino acid as the transmitter of the auditory nerve in the in vitro mouse cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials; Female; Kainic Acid; Male; Mice; Mice, Inbred C3H; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Neurotransmitter; Valine; Vestibulocochlear Nerve | 1985 |
N-methyl-D-aspartate receptor antagonists reduce synaptic excitation in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Conductivity; Electrophysiology; Evoked Potentials; Hippocampus; Membrane Potentials; Microelectrodes; Picrotoxin; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1986 |
Phosphonic analogues of excitatory amino acids raise the threshold for maximal electroconvulsions in mice.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Amino Acids, Dicarboxylic; Animals; Electroshock; Glutamates; Male; Mice; Seizures; Valine | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
A comparison of the effects of quinolinate and N-methyl-aspartate on neurons in rat piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Iontophoresis; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Rats; Valine | 1986 |
Ia afferent excitation of motoneurones in the in vitro new-born rat spinal cord is selectively antagonized by kynurenate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Animals, Newborn; Carbachol; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Male; Motor Neurons; Muscle Spindles; Neurons, Afferent; Rats; Spinal Cord; Spinal Nerve Roots; Strychnine; Synapses; Valine | 1986 |
Phencyclidine-like catalepsy induced by the excitatory amino acid antagonist DL-2-amino-5-phosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Columbidae; Injections, Intraventricular; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1986 |
Ca2+-dependent depolarization and burst firing of rat CA1 pyramidal neurones induced by N-methyl-D-aspartic acid and quinolinic acid: antagonism by 2-amino-5-phosphonovaleric and kynurenic acids.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium; Convulsants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Valine | 1986 |
(+/-)-cis-2,3-Piperidine dicarboxylic acid is a partial N-methyl-D-aspartate agonist in the in vitro rat cerebellar cGMP model.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Quantitative studies of N-methyl-D-aspartate, 2-amino-5-phosphonovalerate and cis-2,3-piperidine dicarboxylate interactions on the neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electrophysiology; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Spinal Cord; Valine | 1986 |
Activity of beta-kainic acid on neocortical neurons in vivo and hippocampal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Hippocampus; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Receptors, Neurotransmitter; Valine | 1986 |
2-Amino-5-phosphonovalerate and Co2+ selectively block depolarization and burst firing of rat hippocampal CA1 pyramidal neurones by N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cobalt; Evoked Potentials; Hippocampus; Iontophoresis; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Tetrodotoxin; Valine | 1986 |
Stimulation-produced spinal inhibition from the midbrain in the rat is mediated by an excitatory amino acid neurotransmitter in the medial medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dipeptides; Electric Stimulation; Lidocaine; Male; Medulla Oblongata; Mesencephalon; Methysergide; Neural Inhibition; Neurotransmitter Agents; Raphe Nuclei; Rats; Reflex; Spinal Cord; Valine | 1986 |
Mode of action of excitatory amino acid receptor antagonists on hippocampal long-lasting potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Valine | 1986 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
Synaptic excitation in cultures of mouse spinal cord neurones: receptor pharmacology and behaviour of synaptic currents.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Glutamates; Glutamic Acid; Mice; Neurons; Pipecolic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Synapses; Time Factors; Valine | 1986 |
Extracellular studies on the role of N-methyl-D-aspartate receptors in epileptiform activity recorded from the kainic acid-lesioned hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1986 |
Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Catalepsy; Columbidae; Dose-Response Relationship, Drug; Injections, Intraventricular; N-Methylaspartate; Phencyclidine; Stereotyped Behavior; Valine | 1986 |
Blockade of N-methyl-D-aspartate-sensitive acidic amino acid receptors inhibits ischemia-induced accumulation of purine catabolites in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Brain Ischemia; Corpus Striatum; Hypoxanthine; Hypoxanthines; Inosine; Male; Purines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xanthine; Xanthines | 1986 |
Exposure of hippocampal slices to quisqualate sensitizes synaptic responses to phosphonate-containing analogues of glutamate.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Evoked Potentials; Glutamates; Hippocampus; In Vitro Techniques; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Stereoisomerism; Synapses; Valine | 1986 |
The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Intrastriatal injection of DL-2-amino-5-phosphonovaleric acid (AP-5) induces sniffing stereotypy that is antagonized by haloperidol and clozapine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Clozapine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Grooming; Haloperidol; Injections; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Valine | 1986 |
CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Brain; Cats; Cell Membrane; Interneurons; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Neurons; Piperazines; Rats; Spinal Cord; Valine | 1986 |
An N-methyl-D-aspartate (NMDA) receptor antagonist reduces bicuculline-induced depolarization shifts in neocortical explant cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Cerebral Cortex; Culture Techniques; Epilepsy; Membrane Potentials; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1986 |
Effects of kynurenic acid on evoked extracellular field potentials in the rat olfactory bulb in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Kynurenic Acid; Male; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Valine | 1986 |
Deep prepyriform cortex kindling and its relation to amygdala kindling in the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; N-Methylaspartate; Rats; Valine | 1986 |
An analysis of the effects of excitatory amino acid receptor antagonists on evoked field potentials in the olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dialysis; Dipeptides; Electric Stimulation; Evoked Potentials; Olfactory Bulb; Pipecolic Acids; Rabbits; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1986 |
Stimulatory effect of N-methyl aspartate on locomotor activity and transmitter release from rat nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Aspartic Acid; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Motor Activity; N-Methylaspartate; Nialamide; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Valine | 1986 |
Evidence for the activation of the N-methyl-D-aspartate receptor during epileptiform discharge.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Epilepsy; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Neural Inhibition; Picrotoxin; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Synaptic Transmission; Valine | 1986 |
Blockade by D-aminophosphonovalerate or Mg2+ of excitatory amino acid-induced responses on spinal motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electric Conductivity; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Synaptic Transmission; Valine | 1986 |
Glutamate and anoxic neuronal death in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Glutamates; Hippocampus; Hypoxia; In Vitro Techniques; Neural Inhibition; Rats; Receptors, Neurotransmitter; Valine | 1986 |
Amino acid receptor mediated excitatory synaptic transmission in the cat red nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cats; Dipeptides; Female; Glutamates; Glutamine; Kynurenic Acid; Male; Neurons; Piperazines; Receptors, Amino Acid; Receptors, Cell Surface; Red Nucleus; Synapses; Synaptic Transmission; Time Factors; Valine | 1986 |
Antagonists of glutaminergic neurotransmission block retinotectal transmission in goldfish.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cyprinidae; Dipeptides; Excitatory Amino Acid Antagonists; Glutamic Acid; Goldfish; In Vitro Techniques; Kynurenic Acid; Pipecolic Acids; Retina; Superior Colliculi; Synaptic Transmission; Time Factors; Valine | 1986 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Rats; Structure-Activity Relationship; Valine | 1987 |
Excitatory amino acids and intracellular pH in motoneurons of the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Valine | 1986 |
Aortic baroreceptor reflexes are mediated by NMDA receptors in caudal ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Aspartic Acid; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Medulla Oblongata; Microinjections; N-Methylaspartate; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Synaptic Transmission; Valine | 1987 |
Comparison of L-[3H]glutamate, D-[3H]aspartate, DL-[3H]AP5 and [3H]NMDA as ligands for NMDA receptors in crude postsynaptic densities from rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
The NMDA receptor antagonist 2-amino-5-phosphonovalerate blocks stimulus train-induced epileptogenesis but not epileptiform bursting in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Long-term potentiation in the hippocampus using depolarizing current pulses as the conditioning stimulus to single volley synaptic potentials.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Conditioning, Psychological; Electric Stimulation; Guinea Pigs; Hippocampus; Picrotoxin; Synapses; Time Factors; Valine | 1987 |
Long-term potentiation in the dentate gyrus: induction and increased glutamate release are blocked by D(-)aminophosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Depression, Chemical; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Male; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
A simple and rapid method for assessing similarities among directly observable behavioral effects of drugs: PCP-like effects of 2-amino-5-phosphonovalerate in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dextroamphetamine; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1987 |
Postsynaptic control of hippocampal long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Evoked Potentials; GABA Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Picrotoxin; Synapses; Valine | 1986 |
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine | 1987 |
An N-methyl-D-aspartate receptor-independent excitatory action of partial reduction of extracellular [Mg2+] in CA1-region of rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Extracellular Space; Hippocampus; In Vitro Techniques; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1987 |
Cytoplasmic calcium elevation in hippocampal granule cell induced by perforant path stimulation and L-glutamate application.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Aspartic Acid; Benzofurans; Calcium; Cytoplasm; Egtazic Acid; Electric Stimulation; Fluorescent Dyes; Fura-2; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neural Pathways; Tetrodotoxin; Valine | 1987 |
Effects of reduced magnesium on hippocampal synchrony.
Topics: 2-Amino-5-phosphonovalerate; Animals; Convulsants; Electrophysiology; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1987 |
Kindling-induced changes in EEG recorded during stimulation from the site of stimulation. III. Direct pharmacological manipulations of the kindled amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Atropine; Baclofen; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Neural Inhibition; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Valine | 1987 |
Bursting in human epileptogenic neocortex is depressed by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anticonvulsants; Aspartic Acid; Epilepsy, Temporal Lobe; Humans; In Vitro Techniques; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Temporal Lobe; Valine | 1987 |
2-Amino-5-phosphonovalerate attenuates the severe hypoglycemia-induced loss of perforant path-evoked field potentials in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Female; Glucose; Hippocampus; Hypoglycemia; Male; Membrane Potentials; Neural Pathways; Rats; Rats, Inbred Strains; Valine | 1987 |
N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Aspartic Acid; Evoked Potentials, Visual; N-Methylaspartate; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Valine | 1987 |
Reticulospinal neurones activate excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Kynurenic Acid; Lampreys; Membrane Potentials; Motor Neurons; Pipecolic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Reticular Formation; Spinal Cord; Valine | 1987 |
The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Valine | 1987 |
Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apnea; Aspartic Acid; Blood Pressure; Carotid Sinus; Cats; Female; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Phrenic Nerve; Quisqualic Acid; Respiration; Vagotomy; Valine; Vasomotor System | 1987 |
Involvement of N-methyl-D-aspartate receptors in epileptiform bursting in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Bicuculline; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1986 |
NMDA receptor antagonist D-APV depresses excitatory activity produced by normorphine in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; In Vitro Techniques; Male; Morphine Derivatives; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellar Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Valine | 1987 |
Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Valine | 1987 |
Blockade of excitatory amino acid receptors protects anoxic hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Conductivity; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Kynurenine; Magnesium; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
Characterization of an N-methyl-D-aspartate receptor component of synaptic transmission in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Culture Techniques; Evoked Potentials; Female; Hippocampus; Magnesium; Neuronal Plasticity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Valine | 1987 |
Facilitated induction of hippocampal long-term potentiation in slices perfused with low concentrations of magnesium.
Topics: 2-Amino-5-phosphonovalerate; Animals; Culture Techniques; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; Magnesium; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1987 |
Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia, General; Animals; Aspartic Acid; Drug Interactions; Female; Halothane; Hippocampus; Ketamine; N-Methylaspartate; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1987 |
Non-competitive regulation of phencyclidine/sigma-receptors by the N-methyl-D-aspartate receptor antagonist D-(-)-2-amino-5-phosphonovaleric acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Glutamates; Glutamic Acid; Humans; Male; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Schizophrenia; Valine | 1987 |
Involvement of N-methyl-D-aspartate receptors in the augmenting response in rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Male; Motor Cortex; Neural Pathways; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Somatosensory Cortex; Thalamic Nuclei; Valine | 1987 |
Inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release by phencyclidine is dependent on potassium concentration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Magnesium Sulfate; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Potassium; Rats; Rats, Inbred Strains; Valine | 1987 |
A role for the ventral surface of the medulla in regulation of nasal resistance.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Airway Resistance; Animals; Aspartic Acid; Blood Pressure; Cats; Lidocaine; Medulla Oblongata; N-Methylaspartate; Nose; Phrenic Nerve; Receptors, Amino Acid; Receptors, Neurotransmitter; Valine | 1987 |
Antagonism of AP-5- and amphetamine-induced behaviour by timelotem as compared with clozapine and haloperidol.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Behavior, Animal; Benzodiazepines; Clozapine; Dibenzazepines; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereotyped Behavior; Valine | 1987 |
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
The expression of N-methyl-D-aspartate-receptor-mediated component during epileptiform synaptic activity in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1987 |
Glutamate acting on NMDA receptors stimulates neurite outgrowth from cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Cerebellum; Glutamates; Kynurenic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Dual action of excitatory amino acids on the metabolism of inositol phosphates in striatal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Carbachol; Cells, Cultured; Corpus Striatum; Glutamates; Inositol Phosphates; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Sugar Phosphates; Valine | 1987 |
Quinolinate is a weak excitant of cortical neurons in cell culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Magnesium; Membrane Potentials; Mice; Pyridines; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Intrathecal N-methyl-D-aspartate (NMDA) activates both nociceptive and antinociceptive systems.
Topics: 2-Amino-5-phosphonovalerate; Analgesia; Animals; Aspartic Acid; Behavior, Animal; Decerebrate State; Injections, Spinal; Male; N-Methylaspartate; Nociceptors; Pain; Rats; Valine | 1987 |
N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Cyanides; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; Mice; Neurons; Oxygen; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Evidence for N-methyl-D-aspartic acid receptor-mediated modulation of the commissural input to central vestibular neurons of the frog.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Anticonvulsants; Aspartic Acid; Brain Stem; Evoked Potentials; Functional Laterality; In Vitro Techniques; Magnesium; Membrane Potentials; Models, Neurological; Neurons; Rana temporaria; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Vestibular Nuclei | 1987 |
The effects of excitatory amino acids and their antagonists on the generation of motor activity in the isolated chick spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Chick Embryo; Convulsants; Dipeptides; In Vitro Techniques; Kynurenic Acid; Motor Activity; Motor Neurons; N-Methylaspartate; Spinal Cord; Valine | 1987 |
Complex synaptic responses of entorhinal cortical cells in the rat to subicular stimulation in vitro: demonstration of an NMDA receptor-mediated component.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Brain; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1987 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Comparison of kynurenic acid and 2-APV suppression of epileptiform activity in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Electrophysiology; Epilepsy; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Osmolar Concentration; Rats; Valine | 1988 |
Synaptic transmission between rat cerebellar granule and Purkinje cells in dissociated cell culture: effects of excitatory-amino acid transmitter antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aspartic Acid; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Purkinje Cells; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 1988 |
Phencyclidine (PCP)-like discriminative stimulus effects of metaphit and of 2-amino-5-phosphonovalerate in pigeons: generality across different training doses of PCP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Chlordiazepoxide; Columbidae; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Pentobarbital; Phencyclidine; Valine | 1987 |
Actions of excitatory amino acid antagonists on geniculo-cortical transmission in the cat's visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electric Stimulation; Evoked Potentials, Visual; Geniculate Bodies; Kainic Acid; Optic Chiasm; Photic Stimulation; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Pathways | 1988 |
Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Alkalosis; Animals; Aspartic Acid; Cerebral Cortex; Epilepsy; In Vitro Techniques; Ketamine; Magnesium Deficiency; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
The pharmacological selectivity of three NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hexamethonium Compounds; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Norepinephrine; Piperazines; Rats; Serotonin; Synaptic Transmission; Valine | 1988 |
Possible role of excitatory amino acids in the convulsant action of catechol.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Catechols; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Electromyography; Female; Pipecolic Acids; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Seizures; Valine | 1988 |
Retardation of amygdala kindling by antagonism of NMD-aspartate and muscarinic cholinergic receptors: evidence for the summation of excitatory mechanisms in kindling.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Kindling, Neurologic; Male; Rats; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Scopolamine; Seizures; Valine | 1988 |
Mode of binding of [3H]dibenzocycloalkenimine (MK-801) to the N-methyl-D-aspartate (NMDA) receptor and its therapeutic implication.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Excitatory amino acid receptors and synaptic transmission in the rat ventrobasal thalamus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Female; Glutamates; Glutamine; Hair; Kynurenic Acid; Male; Neurons; Neurons, Afferent; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Synapses; Synaptic Transmission; Thalamus; Valine; Vibrissae | 1987 |
Properties of glycine-activated conductances in rat brain neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; beta-Alanine; Glycine; Hippocampus; In Vitro Techniques; Male; Medulla Oblongata; Neural Conduction; Neurons; Rats; Taurine; Valine | 1988 |
Unmyelinated cutaneous afferent neurons activate two types of excitatory amino acid receptor in the spinal cord of Xenopus laevis embryos.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Kynurenic Acid; Magnesium; Neurons, Afferent; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Skin; Spinal Cord; Valine; Xenopus laevis | 1988 |
[Action of several amino acids on the vestibular receptors in the frog].
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Axons; In Vitro Techniques; Pipecolic Acids; Ranidae; Receptors, Amino Acid; Receptors, Cell Surface; Semicircular Canals; Valine | 1987 |
Role of N-methyl-D-aspartate receptors in the induction of synaptic potentiation by burst stimulation patterned after the hippocampal theta-rhythm.
Topics: 2-Amino-5-phosphonovalerate; Animals; Convulsants; Electric Stimulation; Electroencephalography; Evoked Potentials; Hippocampus; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Theta Rhythm; Valine | 1988 |
A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Aspartic Acid; Atropine; Binding, Competitive; Dipeptides; Dynorphins; Hot Temperature; Kinetics; Male; N-Methylaspartate; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Changes in the state of the excitatory synaptic system in the hippocampus on prolonged exposure to excitatory amino acids and antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Animals; Aspartic Acid; Dipeptides; Female; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1988 |
Excitatory amino acid antagonists depress acoustic startle after infusion into the ventral nucleus of the lateral lemniscus or paralemniscal zone.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Dipeptides; Dose-Response Relationship, Drug; Glutamates; Glutamine; Hearing; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Reflex, Startle; Valine | 1988 |
A quantitative pharmacological analysis of some excitatory amino acid receptors in the mouse neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1988 |
An excitatory amino acid projection from ventromedial hypothalamus to periaqueductal gray in the rat: autoradiographic and electrophysiological evidence.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Autoradiography; Electric Stimulation; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reaction Time; Valine; Ventromedial Hypothalamic Nucleus | 1988 |
Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Antitussive Agents; Aspartic Acid; Cerebral Cortex; Dextromethorphan; Dextrorphan; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Levorphanol; Morphinans; N-Methylaspartate; Seizures; Valine | 1988 |
The glutamate receptor subtype mediating parallel fibre-Purkinje cell transmission in rabbit cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellar Cortex; Dipeptides; Glutamates; Kynurenic Acid; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rabbits; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1988 |
NMDA receptor activation and early olfactory learning.
Topics: 2-Amino-5-phosphonovalerate; Animals; Learning; Male; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Smell; Valine | 1988 |
Solubilization of rat brain phencyclidine receptors in an active binding form that is sensitive to N-methyl-D-aspartate receptor ligands.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain Chemistry; Cell Membrane; Cholic Acid; Cholic Acids; Detergents; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Solubility; Valine | 1988 |
Effects of D-(-)-aminophosphonovalerate on behavioral and histological changes induced by systemic kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Injections, Intraperitoneal; Kainic Acid; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1988 |
Evidence of N-methyl-D-aspartate receptor-mediated modulation of the aortic baroreceptor reflex in the rat nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Kainic Acid; Male; Medulla Oblongata; Oxadiazoles; Pressoreceptors; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
NMDA- and kainate-evoked GABA release from striatal neurones differentiated in primary culture: differential blocking by phencyclidine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Synaptic and intrinsic responses of medical entorhinal cortical cells in normal and magnesium-free medium in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Reaction Time; Synapses; Valine | 1988 |
Excitatory amino acid antagonists and endogenous aspartate and glutamate release from rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1988 |
Differential control by N-methyl-D-aspartate and kainate of striatal dopamine release in vivo: a trans-striatal dialysis study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Atropine; Carbachol; Corpus Striatum; Dopamine; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
NMDA antagonists: lack of protective effect against hypoxic damage in CA1 region of hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Female; Hippocampus; Hypoxia, Brain; Membrane Potentials; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Enhancement of opioid cataleptic response by cortical frontal deafferentation or intrastriatal injection of NMDA-receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Catalepsy; Cerebral Cortex; Cerebral Ventricles; Corpus Striatum; Female; Kinetics; Methadone; Morphine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Valine | 1988 |
Amino acids modulate calcium permeability of the plasma membrane of human neuroblastoma cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Calcium; Cell Membrane Permeability; Cysteine; Humans; Kainic Acid; N-Methylaspartate; Neuroblastoma; Neurotransmitter Agents; Tumor Cells, Cultured; Valine | 1988 |
Effects of the NMDA antagonist 2AP5 on complex spike discharge by hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Hippocampus; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Effects of excitatory amino acids on the oxygen consumption of hippocampal slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Oxygen Consumption; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spider Venoms; Valine | 1988 |
Influence of dynorphin (1-13) on spinal reflexes in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dynorphins; Electrophysiology; Injections, Spinal; Male; N-Methylaspartate; Nerve Fibers; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Reflex; Spinal Cord; Valine | 1988 |
Synaptic activation of N-methyl-D-aspartate receptors in the Schaffer collateral-commissural pathway of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Female; Hippocampus; In Vitro Techniques; Magnesium; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1988 |
Frequency-dependent N-methyl-D-aspartate receptor-mediated synaptic transmission in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Female; Hippocampus; In Vitro Techniques; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1988 |
Quantitative correlation between tetanus-induced decreases in extracellular calcium and LTP.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Calcium; Electric Stimulation; Extracellular Space; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Homocysteine; Iontophoresis; Ketamine; Male; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Valine | 1988 |
Facilitation of hippocampal long-term potentiation in slices perfused with high concentrations of calcium.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Valine | 1988 |
Slow excitatory postsynaptic currents mediated by N-methyl-D-aspartate receptors on cultured mouse central neurones.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Cells, Cultured; Convulsants; Hippocampus; Magnesium; Mice; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Spinal Cord; Synapses; Time Factors; Valine | 1988 |
Glycine reverses antagonism of N-methyl-D-aspartate (NMDA) by 1-hydroxy-3-aminopyrrolidone-2 (HA-966) but not by D-2-amino-5-phosphonovalerate (D-AP5) on rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Evoked Potentials; Glycine; In Vitro Techniques; N-Methylaspartate; Pyrrolidinones; Rats; Valine | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
Epileptiform activity induced by magnesium-free solution in slices of rat amygdala: antagonism by N-methyl-D-aspartate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anticonvulsants; Epilepsy; In Vitro Techniques; Magnesium; Membrane Potentials; Microelectrodes; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Learning impairment in rats by N-methyl-D-aspartate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Avoidance Learning; Injections, Intraventricular; Learning; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Scopolamine; Valine | 1988 |
The pharmacology of excitatory transmission in the rat olfactory cortex slice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebral Cortex; Electrodes; In Vitro Techniques; Olfactory Bulb; Pipecolic Acids; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1988 |
[3H]D-2-amino-5-phosphonopentanoate as a ligand for N-methyl-D-aspartate receptors in the mammalian central nervous system.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Subcellular Fractions; Temperature; Valine | 1988 |
Structure/activity relations of N-methyl-D-aspartate receptor ligands as studied by their inhibition of [3H]D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Cerebral Cortex; Kinetics; Molecular Conformation; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Subcellular Fractions; Valine | 1988 |
An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrodotoxin; Valine | 1988 |
Low-magnesium epilepsy in rat hippocampal slices: inhibitory postsynaptic potentials in the CA1 subfield.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebrospinal Fluid; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Neural Inhibition; Rats; Synapses; Valine | 1988 |
Behavioural and EEG effects of some excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Injections, Intraventricular; Pipecolic Acids; Rats; Valine | 1988 |
Epileptiform events induced by GABA-antagonists in entorhinal cortical cells in vitro are partly mediated by N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Cerebral Cortex; Epilepsy; In Vitro Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
Lesion-induced vestibular plasticity in the frog: are N-methyl-D-aspartate receptors involved?
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; In Vitro Techniques; Rana temporaria; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine; Vestibular Nuclei | 1988 |
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cations, Divalent; Cells, Cultured; Glycine; Hippocampus; Ketamine; Kynurenic Acid; Magnesium; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Zinc | 1988 |
NMDA- and non-NMDA-receptor components of excitatory synaptic potentials recorded from cells in layer V of rat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; In Vitro Techniques; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine; Visual Cortex | 1988 |
Stimulation of ingestive behaviors following injections of excitatory amino acid antagonists into the median raphe nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Catheterization; Drinking; Eating; Injections; Kynurenic Acid; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Valine | 1988 |
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Decrease of recurrent and feed-forward inhibitions under high pressure of helium in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; gamma-Aminobutyric Acid; Helium; Hippocampus; In Vitro Techniques; Male; Posture; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Valine | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
Effect of minaprine on synaptic transmission in the neocortex of the rat in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Corpus Callosum; Dipeptides; Drug Interactions; Injections, Intravenous; Male; Pyridazines; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Valine | 1988 |
Effect of carbamazepine on stimulus-evoked Ca2+ fluxes in rat hippocampal slices and its interaction with A1-adenosine receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Carbamazepine; Hippocampus; In Vitro Techniques; Membrane Potentials; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synapses; Theophylline; Valine | 1988 |
Release of proteins during long-term potentiation in the hippocampus of the anaesthetized rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Electric Stimulation; Hippocampus; Male; Molecular Weight; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Time Factors; Valine | 1988 |
Ketamine blocks an NMDA receptor-mediated component of synaptic transmission in rat hippocampus in a voltage-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; In Vitro Techniques; Ketamine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1988 |
Glycine potentiates strychnine-induced convulsions: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Drug Synergism; Glycine; Injections, Spinal; Mice; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Strychnine; Valine | 1988 |
Long-term potentiation differentially affects two components of synaptic responses in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Somatosensory; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Synapses; Valine | 1988 |
APV, an N-methyl-D-aspartate receptor antagonist, blocks the hippocampal theta rhythm in behaving rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Valine | 1988 |
Epileptiform activity induced by lowering extracellular [Mg2+] in combined hippocampal-entorhinal cortex slices: modulation by receptors for norepinephrine and N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cerebral Cortex; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1987 |
Kynurenic acid and AP5 distinguish between NMDA receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Ibotenic Acid; Kynurenic Acid; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Do N-methyl-D-aspartate receptors mediate synaptic responses in the mudpuppy retina?
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Aspartic Acid; Electroretinography; Light; N-Methylaspartate; Necturus maculosus; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Stereoisomerism; Synapses; Valine | 1988 |
Contributions of quisqualate and NMDA receptors to the induction and expression of LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; Magnesium; Male; Membrane Potentials; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1988 |
Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ganglia, Spinal; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Amino acid pharmacology in neocortical slices: evidence for bimolecular actions from an extension of the Hill and Gaddum-Schild equations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kynurenic Acid; Mathematics; Mice; N-Methylaspartate; Pyridines; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; In Vitro Techniques; N-Methylaspartate; Neurons; Piperazines; Rats; Reflex; Spine; Valine | 1988 |
Excitatory amino acid receptors intrinsic to synaptic transmission in nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Functional Laterality; Glutamates; In Vitro Techniques; Kynurenic Acid; Male; Medulla Oblongata; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Reference Values; Synapses; Synaptic Transmission; Valine | 1988 |
NMDA receptor blockade prevents the increase in protein kinase C substrate (protein F1) phosphorylation produced by long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; GAP-43 Protein; Hippocampus; Kinetics; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Reference Values; Valine | 1988 |
Long-term potentiation in the dentate gyrus of the anaesthetized rat is accompanied by an increase in protein efflux into push-pull cannula perfusates.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Calcium; Electric Stimulation; Hippocampus; Male; Molecular Weight; Nerve Tissue Proteins; Perfusion; Rats; Rats, Inbred Strains; Time Factors; Valine | 1988 |
Intra-ventricular infusion of the NMDA antagonist AP5 impairs performance on a non-spatial operant DRL task in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Injections, Intraventricular; Male; Memory; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reinforcement, Psychology; Retention, Psychology; Valine | 1988 |
N-methyl-D-aspartate receptor-mediated component of synaptic responses to single-pulse stimulation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebellum; Electric Stimulation; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quisqualic Acid; Turtles; Valine | 1988 |
N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antigens, Surface; Aspartic Acid; Cell Adhesion Molecules; Cell Survival; Cells, Cultured; Cerebellum; N-Methylaspartate; Nerve Tissue Proteins; Potassium; Rats; Rats, Inbred Strains; Valine | 1988 |
Stimulation of NMDA receptors induces proteolysis of spectrin in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium Chloride; Evoked Potentials; Hippocampus; Hydrolysis; In Vitro Techniques; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spectrin; Valine | 1988 |
Calcium accumulation by glutamate receptor activation is involved in hippocampal cell damage after ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Extracellular Space; Hippocampus; Ischemic Attack, Transient; Kainic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Valine | 1988 |
Calcium dependent regulation of catecholamine and serotonin metabolism in human neuroblastoma cells.
Topics: 2-Amino-5-phosphonovalerate; Calcium; Catecholamines; Cell Line; Dopamine; Humans; Neuroblastoma; Serotonin; Valine | 1988 |
Structural requirements for activation of excitatory amino acid receptors in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; In Vitro Techniques; Kynurenic Acid; Male; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1988 |
An N-methyl-D-aspartate receptor mediated excitatory postsynaptic potential evoked in subthalamic neurons in an in vitro slice preparation of the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamic Nuclei; Valine | 1988 |
D-aminophosphonovaleric acid-sensitive spontaneous giant EPSPs in immature rat hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Piperazines; Rats; Synapses; Tetrodotoxin; Valine | 1988 |
Evidence for a specific role for cortical NMDA receptors in slow-wave sleep.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebral Cortex; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sleep; Valine | 1988 |
Long-lasting modification of the synaptic properties of rat CA3 hippocampal neurones induced by kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; Membrane Potentials; Neurons; Potassium; Rats; Synapses; Tetrodotoxin; Valine | 1988 |
Synaptic potentials in rat locus coeruleus neurones.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Neuromuscular Depolarizing Agents; Neurons; Rats; Synapses; Time Factors; Valine | 1988 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
D-aminophosphonovalerate is 100-fold more powerful than D-alpha-aminoadipate in blocking N-methylaspartate neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Female; Hypothalamus; Male; Mice; N-Methylaspartate; Neurons; Organophosphorus Compounds; Structure-Activity Relationship; Valine | 1981 |
Actions of the optical isomers of 2-amino-5-phosphonovalerate as antagonists of excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Neurons; Rats; Spinal Cord; Stereoisomerism; Valine | 1981 |
The effect of 2-amino-4-phosphonobutyrate (APB) on acetylcholine release from the rabbit retina: evidence for on-channel input to cholinergic amacrine cells.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aminobutyrates; Animals; Ion Channels; Neurons; Organophosphorus Compounds; Parasympathetic Nervous System; Rabbits; Retina; Synaptic Transmission; Valine | 1981 |
Motor effects following application of putative excitatory amino acid antagonists to the region of the mesencephalic dopamine cell bodies in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Brain Chemistry; Dipeptides; Dopamine; Female; Injections; Mesencephalon; Motor Activity; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Substantia Nigra; Tegmentum Mesencephali; Valine | 1981 |
Aspartate may be an excitatory transmitter mediating visual excitation of "sustained" but not "transient" cells in the cat retina: iontophoretic studies in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cats; Dipeptides; Glutamates; Glutamic Acid; Neurons; Neurotransmitter Agents; Retina; Synaptic Transmission; Valine | 1982 |
The isomers of 2-amino-5-phosphonovalerate as excitatory amino acid antagonists--a reappraisal.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Stereoisomerism; Time Factors; Valine | 1982 |
Phosphonate analogues of acidic amino acids: inhibition of excitatory amino acid transmitter binding to cerebellar membranes and of the stimulation of cerebellar cyclic GMP levels.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Aminobutyrates; Animals; Cerebellum; Cyclic GMP; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Neurotransmitter; Stereoisomerism; Valine | 1982 |
Some effects of excitatory amino acid receptor antagonists on synaptic transmission in the rat olfactory cortex slice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Aspartic Acid; Culture Techniques; Dipeptides; Electric Stimulation; Evoked Potentials; N-Methylaspartate; Olfactory Bulb; Olfactory Pathways; Pipecolic Acids; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine | 1982 |
Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Ibotenic Acid; Interneurons; Oxazoles; Spinal Cord; Stereoisomerism; Synaptic Transmission; Valine | 1982 |
Actions of N-methyl aspartate and its antagonist aminophosphonovalerate on the A5 catecholamine cell group in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Blood Pressure; Brain; Dose-Response Relationship, Drug; Female; Heart Rate; Male; N-Methylaspartate; Neurons; Rats; Receptors, Adrenergic; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Valine | 1982 |
Intracellular recorded synaptic antagonism in the rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Body Fluids; Dipeptides; Evoked Potentials; Hippocampus; Intracellular Fluid; Rats; Synapses; Valine | 1982 |
Characterization of the excitatory amino acid receptor-mediated release of [3H]acetylcholine from rat striatal slices.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Afferent Pathways; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 1982 |
Antagonists of excitatory amino acids and cyclic guanosine monophosphate in cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Brain Chemistry; Cerebellum; Cyclic GMP; Male; Mice; Valine | 1982 |
alpha-Amino-omega-phosphono carboxylates block ibotenate but not kainate neurotoxicity in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Diseases; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Neurotoxins; Oxazoles; Pyrrolidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valine | 1982 |
Role of excitatory amino acid receptors in mono- and polysynaptic excitation in the cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cats; Dipeptides; Female; Glutamates; Glutamic Acid; Male; Pipecolic Acids; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission; Valine | 1983 |
Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Stem; Cells, Cultured; Embryo, Mammalian; Glutamates; Ibotenic Acid; N-Methylaspartate; Oxazoles; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1983 |
The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Valine | 1983 |
Acidic amino acid antagonists of lateral perforant path synaptic transmission: agonist-antagonist interactions in the dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Animals; Electric Conductivity; Hippocampus; Iontophoresis; Male; Phosphoserine; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Valine | 1982 |
Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rats; Synapses; Valine | 1983 |
A comparison of the anticonvulsant potency of (+/-) 2-amino-5-phosphonopentanoic acid and (+/-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Valine | 1983 |
The kindled amygdala model of epilepsy: anticonvulsant action of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Amygdala; Animals; Anticonvulsants; Epilepsy; Male; Rats; Rats, Inbred Strains; Valine | 1983 |
Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, Papio papio.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Glutamates; Papio; Photic Stimulation; Pipecolic Acids; Seizures; Valine | 1983 |
Functional transmitters at retinal ganglion cells in the cat.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Action Potentials; Animals; Aspartic Acid; Bicuculline; Cats; Dihydro-beta-Erythroidine; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Neurotransmitter Agents; Retina; Retinal Ganglion Cells; Strychnine; Valine | 1983 |
Quinolinic acid evokes [3H]acetylcholine release in striatal slices: mediation by NMDA-type excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Aminobutyrates; Animals; Corpus Striatum; Drug Interactions; In Vitro Techniques; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium; Valine | 1983 |
Verapamil counteracts the masking of long-lasting potentiation of hippocampal population spike produced by 2-amino-5-phosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Hippocampus; In Vitro Techniques; Rats; Rats, Inbred Strains; Time Factors; Valine; Verapamil | 1984 |
Amino acid neurotransmission between fimbria-fornix fibers and neurons in the lateral septum of the rat: a microiontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Iontophoresis; Male; N-Methylaspartate; Nerve Fibers; Neural Pathways; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Septal Nuclei; Synaptic Transmission; Valine | 1984 |
A physiologically active kainic acid-preferring receptor in chicken retina.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Chickens; Dipeptides; Kainic Acid; Photoreceptor Cells; Pipecolic Acids; Receptors, Cell Surface; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Valine | 1984 |
A possible correlate of the postsynaptic condition for long-lasting potentiation in the guinea pig hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Guinea Pigs; Hippocampus; In Vitro Techniques; Picrotoxin; Synapses; Time Factors; Valine | 1984 |
Suppression of audiogenic seizures in DBA/2 mice by two new dipeptide NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Glutamates; Glutamine; Mice; Mice, Inbred DBA; Seizures; Valine | 1984 |
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Cats; Depression, Chemical; Interneurons; Neurotransmitter Agents; Spinal Cord; Stereoisomerism; Synapses; Synaptic Transmission; Valine | 1982 |
The action of some analogues of the excitatory amino acids in the dentate gyrus of the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Dipeptides; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Rats; Stereoisomerism; Synapses; Valine | 1984 |
Effects of excitatory amino-acid antagonists on the anticonvulsant action of phenobarbital or diphenylhydantoin in mice.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Anticonvulsants; Drug Interactions; Electroshock; Glutamates; Male; Mice; Phenobarbital; Phenytoin; Seizures; Valine | 1984 |
A comparison of the effects of N-methyl-D-aspartate and quinolinate on central neurones of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Iontophoresis; Microinjections; N-Methylaspartate; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Somatosensory Cortex; Spinal Cord; Stimulation, Chemical; Valine | 1984 |
The behavioural effects of an N-methylaspartate receptor antagonist following application to the lumbar spinal cord of conscious rats.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Glutamates; Glutamine; Hindlimb; Injections, Spinal; Locomotion; Male; Morphine; Motor Activity; Muscle Contraction; Muscles; Nociceptors; Pipecolic Acids; Posture; Rats; Reaction Time; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tail; Valine | 1984 |
Pharmacological modulation of on and off ganglion cells in the cat retina.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Cats; Iontophoresis; Retina; Retinal Ganglion Cells; Valine | 1984 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
Anticonvulsant action of amino acid antagonists against kindled hippocampal seizures.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Animals; Anticonvulsants; Cerebral Ventricles; Electric Stimulation; Hippocampus; Kindling, Neurologic; Male; Pyramidal Tracts; Rats; Rats, Inbred Strains; Seizures; Valine | 1984 |
The actions of 'selective' excitatory amino acid antagonists on the crustacean neuromuscular junction.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Anomura; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Neuromuscular Junction; Norleucine; Pyridines; Synaptic Transmission; Valine | 1984 |
Lathyrus excitotoxin: mechanism of neuronal excitation by L-2-oxalylamino-3-amino- and L-3-oxalylamino-2-amino-propionic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Cadmium; Cells, Cultured; Fabaceae; Fetus; Iontophoresis; Mice; Neurotoxins; Plants, Medicinal; Spinal Cord; Valine | 1984 |
Autoradiography of D-2-[3H]amino-5-phosphonopentanoate binding sites in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Autoradiography; Binding Sites; Brain; Kinetics; Rats; Rats, Inbred Strains; Valine | 1984 |
Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Animals; Hippocampus; In Vitro Techniques; Male; Norleucine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1984 |
Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cells, Cultured; Dicarboxylic Acids; Drug Synergism; Embryo, Mammalian; Female; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Macrophages; Neuroglia; Neurons; Neurotoxins; Pregnancy; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1993 |
Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors.
Topics: Action Potentials; Adenosine; Alanine; Anesthetics; Animals; Anti-Anxiety Agents; Bicuculline; Corpus Striatum; Culture Techniques; Dose-Response Relationship, Drug; Electric Stimulation; GABA Agonists; GABA Antagonists; Hippocampus; Male; Muscimol; Neuronal Plasticity; Pregnanediones; Pregnanolone; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA; Receptors, Metabotropic Glutamate; Valine | 1995 |
Activation of K+ channels by stimulation of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cycloleucine; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurons; Potassium Channels; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stimulation, Chemical; Valine | 1995 |
NMDA receptor blockade increases in vivo striatal dopamine synthesis and release in rats and mice with incomplete, dopamine-depleting, nigrostriatal lesions.
Topics: Animals; Arginine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Excitatory Amino Acids; Male; Mice; Microdialysis; Nitroarginine; Oxidopamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Valine | 1995 |
[Ketamine inhibits n-methyl-d-aspartate (NMDA) receptor mediated acetylcholine release from rabbit caudate nucleus slices].
Topics: Acetylcholine; Action Potentials; Amantadine; Animals; Caudate Nucleus; Choline; Dizocilpine Maleate; In Vitro Techniques; Ketamine; Memantine; Rabbits; Receptors, N-Methyl-D-Aspartate; Valine | 1994 |
Long-term depression requiring tACPD-receptor activation and NMDA-receptor blockade.
Topics: Animals; Cycloleucine; In Vitro Techniques; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetany; Valine; Visual Cortex | 1994 |
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine | 1993 |
Inactivation of Escherichia coli threonine synthase by DL-Z-2-amino-5-phosphono-3-pentenoic acid.
Topics: Carbon-Oxygen Lyases; Escherichia coli; Lyases; Time Factors; Valine | 1994 |
[Effect of intracerebroventricular injection of N-methyl-D-aspartate on learning and memory in mice].
Topics: Animals; Female; Injections, Intraventricular; Learning; Male; Memory; Mice; N-Methylaspartate; Valine | 1993 |
Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II.
Topics: Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Electric Stimulation; Evoked Potentials; Hippocampus; Kinetics; Male; Marine Toxins; Neurons; Organ Culture Techniques; Oxazoles; Phosphoprotein Phosphatases; Protein Kinases; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1993 |
Hippocampal CA1 lacunosum-moleculare interneurons: modulation of monosynaptic GABAergic IPSCs by presynaptic GABAB receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Interneurons; Male; Neural Inhibition; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Presynaptic; Synaptic Transmission; Valine | 1995 |
Induction of a calcium-dependent long-term enhancement of excitability in the rate olfactory bulb.
Topics: Animals; Calcium; Electric Stimulation; Electrophysiology; Evoked Potentials; Male; Neurons; Olfactory Bulb; Picrotoxin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Valine | 1996 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
Weaver granule neurons are rescued by calcium channel antagonists and antibodies against a neurite outgrowth domain of the B2 chain of laminin.
Topics: Animals; Antibodies, Monoclonal; Calcium Channel Blockers; Cell Movement; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Laminin; Leukocyte L1 Antigen Complex; Mice; Mice, Mutant Strains; Neural Cell Adhesion Molecules; Neurites; Neurons; omega-Conotoxin GVIA; Peptides; Rabbits; Receptors, N-Methyl-D-Aspartate; Valine; Verapamil | 1996 |
An increased intensity of N-methyl-D-aspartate (NMDA) but not non-NMDA receptor activation may be responsible for the enhancement of excitatory processes in the neocortex of two-week-old rats: a brain slices study.
Topics: Action Potentials; Animals; Animals, Suckling; Benzodiazepines; Binding, Competitive; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Antagonists; Organophosphonates; Pentanoic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synaptic Transmission; Valine | 1996 |
Local opioid withdrawal in rat single periaqueductal gray neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Bicuculline; Clonidine; Drug Tolerance; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Membrane Potentials; Morphine; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Periaqueductal Gray; Potassium Channels; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance Withdrawal Syndrome; Tetrodotoxin; Time Factors; Valine | 1996 |
A monosynaptic GABAergic input from the inferior colliculus to the medial geniculate body in rat.
Topics: Animals; Cell Size; Electrophysiology; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Inferior Colliculi; Interneurons; Membrane Potentials; Microspheres; Neural Pathways; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, GABA-B; Synapses; Thalamic Nuclei; Valine | 1997 |
Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Ion Channel Gating; Lysophospholipids; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Glutamate; Valine | 1997 |
Selective depression of the spinal polysynaptic reflex by the NMDA receptor antagonists in an isolated spinal cord in vitro.
Topics: Animals; Depression, Chemical; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Piperazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Reflex, Monosynaptic; Serine; Spinal Cord; Spinal Nerve Roots; Strychnine; Valine | 1997 |
Mossy fibre innervation is not required for the development of kainic acid toxicity in organotypic hippocampal slice cultures.
Topics: Animals; Cell Death; Cell Survival; Hippocampus; In Vitro Techniques; Kainic Acid; Microelectrodes; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Pathways; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Time Factors; Valine | 1998 |
Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonists.
Topics: Alkaloids; Analgesia; Animals; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Escape Reaction; Hindlimb; Hot Temperature; Injections, Spinal; Lobeline; Male; Mecamylamine; Microinjections; Nicotine; Nicotinic Agonists; Pain; Pyridines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine; Vocalization, Animal | 1998 |
Expression of N-methyl-D-aspartate receptors using vaccinia virus causes excitotoxic death in human kidney cells.
Topics: Calcium; Cell Line; Cell Survival; Excitatory Amino Acids; Gene Expression Regulation; Genes, Reporter; Glycoside Hydrolases; Glycosylation; Humans; Immunohistochemistry; Kidney; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Transfection; Tunicamycin; Vaccinia virus; Valine | 1999 |
Mechanisms of calcium influx into hippocampal spines: heterogeneity among spines, coincidence detection by NMDA receptors, and optical quantal analysis.
Topics: Action Potentials; Animals; Calcium; Calcium Channels; Dendrites; Drug Resistance; Electric Stimulation; Electrophysiology; Hippocampus; Optics and Photonics; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Valine | 1999 |
NMDA and non-NMDA receptors mediate responses in the primary gustatory nucleus in goldfish.
Topics: Animals; Brain; Cerebrospinal Fluid; Electric Stimulation; Electrophysiology; Evoked Potentials; Goldfish; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vagus Nerve; Valine | 1999 |
Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Anesthetics, Inhalation; Animals; Biphenyl Compounds; Catheters, Indwelling; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Locomotion; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Synaptic Transmission; Valine | 1999 |
Optical mapping reveals the functional organization of the trigeminal nuclei in the chick embryo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Mapping; Cadmium; Calcium; Carbocyanines; Chick Embryo; Coloring Agents; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Motor Neurons; Neurons; Ophthalmic Nerve; Rhodanine; Synaptic Transmission; Thiazolidines; Trigeminal Nuclei; Valine | 1999 |
Oscillatory interaction between dorsal root excitability and dorsal root potentials in the spinal cord of the turtle.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Receptors, Presynaptic; Spinal Nerve Roots; Turtles; Valine | 1999 |
Effects of lesions to the glutamatergic afferents to the nucleus accumbens in the modulation of reactivity to spatial and non-spatial novelty in mice.
Topics: Afferent Pathways; Amygdala; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Hippocampus; Ibotenic Acid; Injections; Limbic System; Mice; Models, Neurological; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Spatial Behavior; Valine | 1999 |
Analysis of NMDA-independent long-term potentiation induced at CA3-CA1 synapses in rat hippocampus in vitro.
Topics: Animals; Calcium; Cerebrospinal Fluid; Electrophysiology; Excitatory Postsynaptic Potentials; Female; Hippocampus; Long-Term Potentiation; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Valine | 1999 |
Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons.
Topics: Analgesics, Opioid; Animals; Calcium; Cell Survival; Dizocilpine Maleate; Dynorphins; Embryo, Mammalian; Kynurenic Acid; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Neurotoxins; Peptide Fragments; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1999 |
Facilitation of cholinergic transmission by substance P methyl ester in the mouse hippocampal slice preparation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Cholinergic Agonists; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; Male; Membrane Potentials; Mice; Patch-Clamp Techniques; Piperidines; Pyramidal Cells; Quinuclidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Tetrodotoxin; Valine | 2000 |
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine | 2000 |
Contributions of intrinsic and synaptic activities to the generation of neuronal discharges in in vitro hippocampus.
Topics: Action Potentials; Animals; Calibration; Excitatory Postsynaptic Potentials; Extracellular Space; Guinea Pigs; Hippocampus; In Vitro Techniques; Microelectrodes; Neurons; Patch-Clamp Techniques; Potassium; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, Presynaptic; Synapses; Valine | 2000 |
Laminar characteristics of functional connectivity in rat barrel cortex revealed by stimulation with caged-glutamate.
Topics: Animals; Brain Mapping; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Neural Pathways; Neurons; Photic Stimulation; Photolysis; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Somatosensory Cortex; Synapses; Time Factors; Valine; Vibrissae | 2000 |
Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray.
Topics: Amygdala; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Naltrexone; Narcotic Antagonists; Neural Pathways; Neurons; Neurotensin; Nociceptors; Pain; Peptides; Periaqueductal Gray; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Opioid, delta; Receptors, Opioid, mu; Time Factors; Valine | 2000 |
Spatial working memory is independent of hippocampal CA1 long-term potentiation in rats.
Topics: Animals; Brain Mapping; Cholinergic Agents; Discrimination Learning; Escape Reaction; Hemicholinium 3; Hippocampus; Injections, Intraventricular; Long-Term Potentiation; Male; Mental Recall; Neurons; Orientation; Pirenzepine; Rats; Rats, Inbred F344; Receptor, Muscarinic M1; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Valine | 2000 |
Aberrant neuronal physiology in the basal nucleus of the amygdala in a model of chronic limbic epilepsy.
Topics: Action Potentials; Amygdala; Animals; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Kindling, Neurologic; Neural Pathways; Neurons; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Valine | 2000 |
Impairment of conditioned contextual fear of C57BL/6J mice by intracerebral injections of the NMDA receptor antagonist APV.
Topics: Animals; Association Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Hippocampus; Injections, Intraventricular; Male; Memory, Short-Term; Mice; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; Valine | 2000 |
Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine | 2000 |
NiCl2 and amiloride induce spreading depression in guinea pig hippocampal slices.
Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cortical Spreading Depression; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nickel; Valine | 2000 |
The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in rats.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Imidazoles; Injections, Spinal; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Effects of pituitary adenylate cyclase activating polypeptide on lumbosacral preganglionic neurons in the neonatal rat spinal cord.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amidines; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; Glycine Agents; Lumbar Vertebrae; Neurons; Neuropeptides; Parasympathetic Nervous System; Patch-Clamp Techniques; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sacrum; Spinal Cord; Strychnine; Valine | 2001 |
NMDA-responsible, APV-insensitive receptor in cultured human astrocytes.
Topics: Astrocytes; Calcium; Cells, Cultured; Glial Fibrillary Acidic Protein; Glycine; GTP-Binding Proteins; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Peripheral group I metabotropic glutamate receptors modulate nociception in mice.
Topics: Animals; Chromones; Excitatory Amino Acid Antagonists; Glycine; Hindlimb; Hot Temperature; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain; Pain Measurement; Pyridines; Receptors, Metabotropic Glutamate; Valine | 2001 |
PKC activation rescues LTP from NMDA receptor blockade.
Topics: Animals; Enzyme Activation; Lip; Male; Mice; Mice, Inbred C57BL; Phorbol 12,13-Dibutyrate; Presynaptic Terminals; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Stress-induced increase in extracellular dopamine in striatum: role of glutamatergic action via N-methyl-D-aspartate receptors in substantia nigra.
Topics: Animals; Dopamine; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Hydrazines; Male; Microdialysis; Neostriatum; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Substantia Nigra; Valine | 2001 |
NMDA and dopamine D2 receptors in the caudate-putamen are not involved in control of motor readiness in rats.
Topics: Animals; Caudate Nucleus; Conditioning, Psychological; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Male; Motor Skills; Putamen; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
MAP2 phosphorylation and visual plasticity in Xenopus.
Topics: Aging; Animals; Dendrites; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Glutamic Acid; Immunoblotting; Microtubule-Associated Proteins; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Valine; Vision, Binocular; Visual Pathways; Xenopus laevis | 2001 |
Developmentally restricted synaptic plasticity in a songbird nucleus required for song learning.
Topics: Afferent Pathways; Aging; Animals; Axons; Electric Stimulation; Excitatory Amino Acid Antagonists; Learning; Long-Term Potentiation; Male; Membrane Potentials; Neostriatum; Neurons; Receptors, N-Methyl-D-Aspartate; Songbirds; Synaptic Transmission; Valine; Vocalization, Animal | 2001 |
Nicotine facilitates glycine release in the rat spinal dorsal horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Bacterial Toxins; Bicuculline; Bungarotoxins; Calcium; Calcium Channels; Choline; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Marine Toxins; Mecamylamine; Microcystins; Nerve Endings; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Gelatinosa; Tetrodotoxin; Tropanes; Valine | 2001 |
Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of a novel antagonist PPDC.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Glycine; Hot Temperature; Piperidines; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat.
Topics: Afferent Pathways; Animals; Cell Count; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Inflammation; Male; Muscle, Skeletal; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Skin; Synaptic Transmission; Turpentine; Valine | 2001 |
NMDA and muscarinic blockade in the perirhinal cortex impairs object discrimination in rats.
Topics: Acetylcholine; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memory, Short-Term; Muscarinic Antagonists; Neurons; Parahippocampal Gyrus; Pattern Recognition, Visual; Photic Stimulation; Rats; Rats, Long-Evans; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Scopolamine; Synaptic Transmission; Valine | 2001 |
Remodeling of synaptic actin induced by photoconductive stimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Aniline Compounds; Animals; Calcium; Cells, Cultured; Cyclic AMP; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Genes, Reporter; Green Fluorescent Proteins; Hippocampus; Light; Luminescent Proteins; Microscopy, Video; Neuronal Plasticity; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Signal Transduction; Silicon; Synapses; Thionucleotides; Valine; Xanthenes | 2001 |
Synergistic enhancement of glutamate-mediated responses by serotonin and forskolin in adult mouse spinal dorsal horn neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenylyl Cyclases; Animals; Colforsin; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Posterior Horn Cells; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serotonin; Valine | 2002 |
Contributions of receptor desensitization and saturation to plasticity at the retinogeniculate synapse.
Topics: Animals; Benzothiadiazines; Biphenyl Compounds; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Geniculate Bodies; In Vitro Techniques; Mice; Neuronal Plasticity; Patch-Clamp Techniques; Propionates; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Valine; Visual Pathways | 2002 |
Distinct NMDA receptors provide differential modes of transmission at mossy fiber-interneuron synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Chlorides; Cyclopropanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Mossy Fibers, Hippocampal; N-Methylaspartate; Patch-Clamp Techniques; Phenols; Piperidines; Polyamines; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2002 |
Long-term depression and long-term potentiation in horizontal connections of the barrel cortex.
Topics: Animals; Brain Mapping; Cerebral Cortex; Electric Stimulation; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Membrane Potentials; Mice; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Valine; Vibrissae | 2002 |
Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Homovanillic Acid; Methamphetamine; Microdialysis; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Valine | 2003 |
Differential efficacy of intrathecal NMDA receptor antagonists on inflammatory mechanical and thermal hyperalgesia in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Treatment Outcome; Valine | 2003 |
Functional NMDA receptor channels generated by NMDAR2B gene transfer in rat cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Immunohistochemistry; Infections; Luminescent Proteins; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, N-Methyl-D-Aspartate; Sindbis Virus; Valine | 2003 |
Expression of the specific type IV phosphodiesterase gene PDE4B3 during different phases of long-term potentiation in single hippocampal slices of rats in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Animals, Newborn; Bacterial Proteins; Blotting, Northern; Blotting, Western; Cyclic Nucleotide Phosphodiesterases, Type 4; Electric Stimulation; Electrophysiology; Gene Expression; Hemolysin Proteins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neurofilament Proteins; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Valine | 2003 |
How does prolonged caloric restriction ameliorate age-related impairment of long-term potentiation in the hippocampus?
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Arachidonic Acid; Calcium; Calcium Signaling; Caloric Restriction; Docosahexaenoic Acids; Excitatory Amino Acid Antagonists; Fatty Acids, Unsaturated; Food Deprivation; Hippocampus; Long-Term Potentiation; Male; Membrane Lipids; N-Methylaspartate; Neural Pathways; Neurons; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2003 |
Stimulation of luteinizing hormone secretion by N-methyl-D,L-aspartic acid in the adult male guinea-pig: incomplete blockade by gonadotropin-releasing hormone receptor antagonism.
Topics: Animals; Gonadotropin-Releasing Hormone; Guinea Pigs; Luteinizing Hormone; Male; N-Methylaspartate; Receptors, LHRH; Valine | 2003 |
Developmental and regional differences in the consolidation of long-term potentiation.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Integrin alpha Chains; Long-Term Potentiation; Male; Neural Pathways; Oligopeptides; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2003 |
Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY(93)-->ALA) mutation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Alanine; Animals; Avoidance Learning; Calcium; Cell Membrane; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Electric Stimulation; Genotype; Glycine; Gyrus Cinguli; Humans; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Motor Activity; Mutation; Neural Pathways; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinpirole; Superoxide Dismutase; Valine | 2003 |
Cellular mechanisms of the trigeminally evoked startle response.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Animals; Animals, Newborn; Brain Stem; Carbocyanines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; Glycine Agents; Habituation, Psychophysiologic; In Vitro Techniques; Neurons, Afferent; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Reflex, Startle; Refractory Period, Electrophysiological; Strychnine; Synaptic Transmission; Trigeminal Nerve; Valine | 2003 |
Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Models, Neurological; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex, Monosynaptic; Spinal Cord; Synapses; Time Factors; Valine | 2003 |
Spinal sensitization mechanism in vincristine-induced hyperalgesia in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Elapid Venoms; Hyperalgesia; Male; Mice; Neurokinin-1 Receptor Antagonists; omega-Agatoxin IVA; omega-Conotoxins; Pain Measurement; Pain Threshold; Quinuclidines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors; Valine; Vincristine | 2003 |
Serotonin type II receptor activation facilitates synaptic plasticity via N-methyl-D-aspartate-mediated mechanism in the rat basolateral amygdala.
Topics: Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indophenol; Ketanserin; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Synaptic Transmission; Time Factors; Valine | 2003 |
Transduction of light in the suprachiasmatic nucleus: evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin.
Topics: Animals; Autoradiography; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Light; Male; Melatonin; Microinjections; N-Methylaspartate; Nuclear Proteins; Pineal Gland; Quinoxalines; Radioimmunoassay; RNA, Messenger; Suprachiasmatic Nucleus; Valine | 2003 |
Excitatory GABA input directly drives seizure-like rhythmic synchronization in mature hippocampal CA1 pyramidal cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetazolamide; Animals; Animals, Newborn; Anti-Ulcer Agents; Atropine; Bicuculline; Carbenoxolone; Carbonic Anhydrase Inhibitors; Chlorides; Drug Interactions; Electric Conductivity; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Fluorides; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Muscarinic Antagonists; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Rats, Wistar; Seizures; Valine | 2003 |
Glutamate release in the nucleus accumbens is involved in behavioral depression during the PORSOLT swim test.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Male; Microdialysis; Microinjections; Motor Activity; Nucleus Accumbens; Physical Stimulation; Rats; Rats, Sprague-Dawley; Swimming; Tail; Time Factors; Valine | 2003 |
Involvement of post-synaptic kainate receptors during synaptic transmission between unitary connections in rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Dicarboxylic Acids; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Neocortex; Neural Pathways; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyramidal Cells; Pyrrolidines; Rats; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission; Time Factors; Valine | 2003 |
Protein kinase C and ERK involvement in dendritic spine plasticity in cultured rodent hippocampal neurons.
Topics: Activating Transcription Factor 1; Analysis of Variance; Animals; Animals, Newborn; Cell Size; Cells, Cultured; Culture Media, Conditioned; Dendrites; DNA-Binding Proteins; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; Imaging, Three-Dimensional; Immunohistochemistry; In Vitro Techniques; Luminescent Proteins; Mice; Mitogen-Activated Protein Kinases; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Kinase C; Quinoxalines; Rats; Time Factors; Transcription Factors; Transfection; Valine | 2003 |
Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII.
Topics: Alanine; Anesthetics, Local; Animals; Animals, Newborn; Aspartic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Count; Cell Surface Extensions; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Immunohistochemistry; Luminescent Proteins; Lysine; Mutation; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Organ Culture Techniques; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Long-Evans; Synapses; Synapsins; Synaptic Transmission; Tetrodotoxin; Threonine; Transfection; Valine | 2003 |
Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory.
Topics: Animals; Antirheumatic Agents; Bacterial Proteins; Behavior, Animal; Blotting, Western; Colforsin; Conditioning, Psychological; Cues; Cyclic AMP; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Enzymologic; Hippocampus; Immunoenzyme Techniques; In Situ Hybridization; Interleukin 1 Receptor Antagonist Protein; Long-Term Potentiation; Memory; Metalloproteins; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Neuronal Plasticity; Prosencephalon; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; rap1 GTP-Binding Proteins; Reaction Time; RNA, Messenger; Sialoglycoproteins; Signal Transduction; Subcellular Fractions; Synapses; Synaptic Transmission; Tetanus; Theta Rhythm; Valine | 2003 |
Neurological phenotype and synaptic function in mice lacking the CaV1.3 alpha subunit of neuronal L-type voltage-dependent Ca2+ channels.
Topics: Animals; Behavior, Animal; Binding Sites; Body Weight; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Case-Control Studies; Deoxyadenine Nucleotides; Dose-Response Relationship, Drug; Drinking; Ear; Eating; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; Immunohistochemistry; In Situ Hybridization; Isotope Labeling; Isradipine; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Oligonucleotide Probes; Pain Threshold; Phenotype; Rats; Rotation; Synapses; Time Factors; Valine | 2003 |
In vitro reconstitution of signal transmission from a hair cell to the growth cone of a chick vestibular ganglion cell.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Calcium; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Fura-2; Ganglia, Sensory; Glutamic Acid; Growth Cones; Hair Cells, Vestibular; Hippocampus; Immunohistochemistry; In Vitro Techniques; Neural Conduction; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Signal Transduction; Time Factors; Valine; Vestibule, Labyrinth | 2003 |
Pre-training prevents context fear conditioning deficits produced by hippocampal NMDA receptor blockade.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Fear; Female; Hippocampus; Learning; Male; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Valine | 2003 |
Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Acyclovir; Animals; Animals, Newborn; Atropine; Bicuculline; Bungarotoxins; Carrier Proteins; Cell Count; Choline; Chromones; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Membrane Transport Proteins; Microscopy, Electron; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Septum of Brain; Synapses; Tetrodotoxin; Tubocurarine; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2003 |
Synaptic and membrane properties of neurons in the dorsomedial hypothalamus.
Topics: Amino Acids; Analysis of Variance; Anesthetics, Local; Animals; Bicuculline; Cell Membrane; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Hypothalamus; In Vitro Techniques; Male; Membrane Potentials; Neural Conduction; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Synapses; Tetrodotoxin; Valine | 2003 |
Topiramate alters excitatory synaptic transmission in mouse hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Calcium; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fructose; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neural Inhibition; Synaptic Transmission; Time Factors; Topiramate; Valine | 2003 |
Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes.
Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cell Line; Cells, Cultured; Coculture Techniques; Cycloleucine; Cytosol; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Epithelial Cells; Glutamic Acid; Green Fluorescent Proteins; Humans; Indomethacin; Luminescent Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Patch-Clamp Techniques; Prostaglandins; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Transfection; Valine; Xanthones | 2003 |
Serofendic acid prevents acute glutamate neurotoxicity in cultured cortical neurons.
Topics: Animals; Calcium; Cattle; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Fetal Blood; Fetus; Ionomycin; Neurons; Neurotoxicity Syndromes; Nitric Oxide; Quinoxalines; Rats; S-Nitrosothiols; Sodium Glutamate; Time Factors; Valine | 2003 |
Synaptic plasticity in rat subthalamic nucleus induced by high-frequency stimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Subthalamic Nucleus; Synapses; Time Factors; Valine | 2003 |
Hydrogen peroxide increases the activity of rat sympathetic preganglionic neurons in vivo and in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Autonomic Fibers, Preganglionic; Blood Pressure; Catalase; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Heart Rate; Hydrogen Peroxide; In Vitro Techniques; Injections, Spinal; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors; Valine | 2003 |
Distinct roles of the different ionotropic glutamate receptors within the nucleus accumbens in passive-avoidance learning and memory in mice.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Excitatory Amino Acid Antagonists; Male; Memory; Mice; Nucleus Accumbens; Quinoxalines; Reaction Time; Receptors, Glutamate; Staining and Labeling; Time Factors; Valine | 2003 |
The rat nucleus accumbens is involved in guiding of instrumental responses by stimuli predicting reward magnitude.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Valine | 2003 |
Reduction of glycine receptor-mediated miniature inhibitory postsynaptic currents in rat spinal lamina I neurons after peripheral inflammation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Freund's Adjuvant; GABA Antagonists; Glycine Agents; In Vitro Techniques; Inflammation; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Spinal Cord; Strychnine; Synapses; Tetrodotoxin; Valine | 2003 |
Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adaptor Proteins, Signal Transducing; Alternative Splicing; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; COP-Coated Vesicles; COS Cells; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Endoplasmic Reticulum; Excitatory Amino Acid Antagonists; Exons; GABA Antagonists; Green Fluorescent Proteins; Hippocampus; Immunoblotting; Luminescent Proteins; Membrane Potentials; Models, Biological; Mutation; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Synapses; Tetrodotoxin; Time Factors; Transfection; Valine | 2003 |
Differential actions of diazepam and zolpidem in basolateral and central amygdala nuclei.
Topics: Amygdala; Animals; Animals, Newborn; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; In Vitro Techniques; Male; Neural Inhibition; Patch-Clamp Techniques; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine; Zolpidem | 2004 |
Dopamine receptor supersensitivity in rat subthalamus after 6-hydroxydopamine lesions.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Functional Laterality; In Vitro Techniques; Male; Neural Inhibition; Oxidopamine; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Subthalamic Nucleus; Sympatholytics; Time Factors; Valine | 2003 |
Depression of mGluR-mediated IPSCs by 5-HT in dopamine neurons of the rat substantia nigra pars compacta.
Topics: Animals; Animals, Newborn; Apamin; Calcium; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Methoxyhydroxyphenylglycol; Neural Conduction; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Serotonin; Serotonin Agents; Substantia Nigra; Valine | 2003 |
Non-calyceal excitatory inputs mediate low fidelity synaptic transmission in rat auditory brainstem slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Auditory Pathways; Brain Stem; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2003 |
Restoration of spontaneous exploratory behaviors with an intrathecal NMDA receptor antagonist or a PKC inhibitor in rats with acute pancreatitis.
Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Injections, Spinal; Male; Pancreatitis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2004 |
Activation of long-term synaptic plasticity causes suppression of epileptiform activity in rat hippocampal slices.
Topics: Animals; Bicuculline; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Epilepsy; Excitatory Amino Acid Agonists; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neural Inhibition; Neuronal Plasticity; Rats; Synaptic Transmission; Time Factors; Valine | 2004 |
Involvement of endogeneous glutamate in the stimulatory effect of norepinephrine and serotonin on the hypothalamo-pituitary-adrenocortical axis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Pituitary-Adrenal System; Quinoxalines; Radioimmunoassay; Rats; Serotonin; Serotonin Receptor Agonists; Valine | 2004 |
Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity.
Topics: Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Electrophysiology; Embryo, Mammalian; Homocysteine; Hyperhomocysteinemia; N-Methylaspartate; Neocortex; Nerve Net; Neural Inhibition; Rats; Rats, Wistar; Valine | 2004 |
Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Aminobutyrates; Animals; Binding Sites; Darkness; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Light; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Photons; Retina; Retinal Rod Photoreceptor Cells; Synapses; Synaptic Transmission; Valine; Xanthenes | 2004 |
Afferent modulation of neonatal rat respiratory rhythm in vitro: cellular and synaptic mechanisms.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Brain Stem; Exhalation; In Vitro Techniques; Inhalation; Lung; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Respiratory System; Spinal Nerve Roots; Strychnine; Synapses; Valine | 2004 |
Failure to form a stable topographic map during optic nerve regeneration: abnormal activity-dependent mechanisms.
Topics: Animals; Blotting, Western; Brain Mapping; Electrophysiology; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Immunohistochemistry; Lizards; Nerve Crush; Nerve Regeneration; Optic Nerve; Optic Nerve Injuries; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2003 |
Amygdalar NMDA receptors control the expression of associative reflex facilitation and three other conditional responses.
Topics: Amygdala; Animals; Association Learning; Conditioning, Eyelid; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2004 |
Electrophysiological characterization of synaptic connections between layer VI cortical cells and neurons of the nucleus reticularis thalami in juvenile rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Neural Conduction; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium; Quinoxalines; Rats; Rats, Wistar; Synapses; Thalamic Nuclei; Valine | 2004 |
Local gamma-aminobutyric acid and glutamate circuit control of hypophyseotrophic corticotropin-releasing factor neuron activity in the paraventricular nucleus of the hypothalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Corticotropin-Releasing Hormone; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Microscopy, Electron; Neurons; Organ Culture Techniques; Paraventricular Hypothalamic Nucleus; Radiometry; Rats; Rats, Sprague-Dawley; Synapses; Valine | 2004 |
Characterization of a fast transient outward current in neocortical neurons from epilepsy patients.
Topics: Adolescent; Adult; Anesthetics, Local; Anti-Arrhythmia Agents; Cadmium; Child, Preschool; Epilepsy; Female; Flecainide; Humans; In Vitro Techniques; Male; Membrane Potentials; Middle Aged; Neocortex; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Tetraethylammonium; Tetrodotoxin; Valine | 2004 |
A proportional but slower NMDA potentiation follows AMPA potentiation in LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transfection; Valine; Visual Cortex | 2004 |
Effects of manipulation of N-methyl-D-aspartate receptors on imipenem/cilastatin-induced seizures in rats.
Topics: Acetamides; Animals; Binding Sites; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Electroencephalography; Imipenem; Male; Pyrrolidinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Valine | 2004 |
Fentanyl inhibits GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Animals, Newborn; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fentanyl; gamma-Aminobutyric Acid; Glycine Agents; Heart; In Vitro Techniques; Medulla Oblongata; Membrane Potentials; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Somatostatin; Strychnine; Synaptic Transmission; Tetrodotoxin; Vagus Nerve; Valine | 2004 |
Distinct mechanisms of bidirectional activity-dependent synaptic plasticity in superficial and deep layers of rat entorhinal cortex.
Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Models, Neurological; Neuronal Plasticity; Nifedipine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine | 2004 |
Enhancement of excitatory postsynaptic potentials by preceding application of acetylcholine in mesencephalic dopamine neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Animals, Newborn; Atropine; Chelating Agents; Dopamine; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mesencephalon; Muscarinic Antagonists; Neurons; Nickel; ortho-Aminobenzoates; Patch-Clamp Techniques; Pertussis Toxin; Phenytoin; Rats; Thapsigargin; Time Factors; Valine | 2004 |
Dependence of calcium influx in neocortical cells on temporal structure of depolarization, number of spikes, and blockade of NMDA receptors.
Topics: Action Potentials; Animals; Calcium; Electric Stimulation; Fluorescent Dyes; In Vitro Techniques; Membrane Potentials; Neurons; Organic Chemicals; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Valine; Visual Cortex | 2004 |
Subthreshold contribution of N-methyl-d-aspartate receptors to long-term potentiation induced by low-frequency pairing in rat hippocampal CA1 pyramidal cells.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Kynurenic Acid; Long-Term Potentiation; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2004 |
Frequency-dependent requirement for calcium store-operated mechanisms in induction of homosynaptic long-term depression at hippocampus CA1 synapses.
Topics: Animals; Animals, Newborn; Caffeine; Calcium; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Indoles; Long-Term Synaptic Depression; Nerve Tissue Proteins; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Ruthenium Red; Ryanodine; Synapses; Thapsigargin; Valine | 2004 |
NMDA receptor-mediated depolarizing after-potentials in the basal dendrites of CA1 pyramidal neurons.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; Gallopamil; Hippocampus; Lidocaine; Male; Models, Neurological; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Statistics, Nonparametric; Valine | 2004 |
Retrograde amnesia induced by drugs acting on different molecular systems.
Topics: Amnesia, Retrograde; Animals; Avoidance Learning; Behavior, Animal; Brain; Butadienes; Enzyme Inhibitors; GABA Agonists; Male; Muscimol; Neural Inhibition; Nitriles; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2004 |
Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Bicuculline; Calbindin 2; Calcium; Calcium-Binding Proteins; Cell Count; Cell Size; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Nerve Net; Parvalbumins; Picrotoxin; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Time Factors; Valine | 2004 |
Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Blotting, Northern; Blotting, Western; Dendrites; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Immunohistochemistry; In Situ Hybridization; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron; Models, Neurological; Nerve Tissue Proteins; Neurofilament Proteins; Neurons; p21-Activated Kinases; Prosencephalon; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Rats; Retention, Psychology; Silver Staining; Spatial Behavior; Synapses; Synaptophysin; Time Factors; Valine | 2004 |
Stimulation of N-methyl-D-aspartate receptors, AMPA receptors or metabotropic glutamate receptors leads to rapid internalization of AMPA receptors in cultured nucleus accumbens neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Immunohistochemistry; Male; Neurons; Nucleus Accumbens; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2004 |
Brain-derived neurotrophic factor acutely depresses excitatory synaptic transmission to GABAergic neurons in visual cortical slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Immunoglobulin G; In Vitro Techniques; Isoenzymes; Luminescent Proteins; Lysine; Mice; Mice, Transgenic; Neural Inhibition; Neurons; Parvalbumins; Receptor, trkB; Synaptic Transmission; Valine; Visual Cortex | 2004 |
Morpho-functional characterization of neuronal cells at different stages of maturation in granule cell layer of adult rat dentate gyrus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium Channel Blockers; Carbocyanines; Cellular Senescence; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Microscopy, Confocal; Neural Cell Adhesion Molecule L1; Neurons; Patch-Clamp Techniques; Perforant Pathway; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialic Acids; Synapses; Synaptic Transmission; Tetrodotoxin; Tubulin; Valine; Verapamil | 2004 |
Intracellular pH and KATP channel activity in dorsal vagal neurons of juvenile rats in situ during metabolic disturbances.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyanides; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fluoresceins; Glucose; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Intracellular Space; Male; Membrane Potentials; Membrane Proteins; Neurons; Patch-Clamp Techniques; Potassium Channels; Rats; Rotenone; Time Factors; Vagus Nerve; Valine | 2004 |
Functional re-establishment of the perforant pathway in organotypic co-cultures on microelectrode arrays.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Brain Mapping; Carbocyanines; Coculture Techniques; Complement C3d; Dentate Gyrus; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Antagonists; GABA Antagonists; Immunohistochemistry; Indoles; Membrane Potentials; Mice; Mice, Inbred BALB C; Microelectrodes; Nerve Regeneration; Nerve Tissue Proteins; Neural Cell Adhesion Molecules; Organ Culture Techniques; Perforant Pathway; Pyrimidines; Pyrrolidinones; Recovery of Function; Signal Transduction; Time Factors; Valine | 2004 |
A molecular technique for detecting the liberation of intracellular zinc in cultured neurons.
Topics: Animals; Cadmium; Cells, Cultured; Cerebral Cortex; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Genes, Reporter; Intracellular Space; Luciferases; Models, Neurological; Molecular Probe Techniques; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor MTF-1; Transcription Factors; Valine; Zinc | 2004 |
Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rats.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Long-Term Potentiation; N-Methylaspartate; Nervous System Physiological Phenomena; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Valine | 2004 |
Heterosynaptic co-activation of glutamatergic and dopaminergic afferents is required to induce persistent long-term potentiation.
Topics: Animals; Benzazepines; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neurons, Afferent; Rats; Rats, Wistar; Synapses; Time Factors; Valine | 2004 |
Characterisation of the effects of ATPA, a GLU(K5) kainate receptor agonist, on GABAergic synaptic transmission in the CA1 region of rat hippocampal slices.
Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Membrane Potentials; Neural Inhibition; Propionates; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission; Valine | 2004 |
Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Microtubule-Associated Proteins; Neocortex; Neurons; Patch-Clamp Techniques; Protein Conformation; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2004 |
Bi-directional plasticity and age-dependent long-term depression at mouse CA3-CA1 hippocampal synapses.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Synapses; Valine | 2004 |
Functional properties of electrical synapses between inhibitory interneurons of neocortical layer 4.
Topics: Analysis of Variance; Animals; Animals, Newborn; Electric Stimulation; Electrodes; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; In Vitro Techniques; Interneurons; Models, Neurological; Neocortex; Neural Inhibition; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Synapses; Synaptic Transmission; Time Factors; Valine | 2005 |
Post-synaptic GABA(B) receptors--possible controllers of coincidence detection?
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Baclofen; Chickens; Electric Impedance; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Neurons; Prosencephalon; Receptors, GABA-B; Synapses; Synaptic Transmission; Valine | 2004 |
Differentiation of mouse embryonic stem cells into a defined neuronal lineage.
Topics: Animals; Bicuculline; Blotting, Western; Calmodulin-Binding Proteins; Carrier Proteins; Cell Count; Cell Differentiation; Cell Lineage; Cells, Cultured; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; GABA Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Homeodomain Proteins; Immunohistochemistry; Indoles; Intermediate Filament Proteins; Membrane Potentials; Mice; Nerve Tissue Proteins; Nestin; Neuroglia; Neurogranin; Neurons; Paired Box Transcription Factors; Patch-Clamp Techniques; PAX6 Transcription Factor; Quinoxalines; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, AMPA; Receptors, Nerve Growth Factor; Repressor Proteins; Stem Cells; Synaptophysin; Tetrodotoxin; Time Factors; Tretinoin; Tubulin; Valine | 2004 |
NR2B receptors are involved in the mediation of spinal segmental reflex potentials but not in the cumulative motoneuronal depolarization in vitro.
Topics: Animals; Animals, Newborn; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Neural Inhibition; Physical Stimulation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Spinal Nerve Roots; Valine | 2004 |
Capsaicin-evoked substance P release in rat dorsal horn increases after peripheral inflammation: a microdialysis study.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Freund's Adjuvant; Male; Microdialysis; Neurogenic Inflammation; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Time Factors; Valine | 2004 |
Role of N-methyl-D-aspartate receptors in gastric mucosal blood flow induced by histamine.
Topics: Acids; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspartic Acid; Cimetidine; Drug Interactions; Gastric Mucosa; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Immunohistochemistry; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Time Factors; Tripelennamine; Valine; Yohimbine | 2004 |
The effects of corticotropin-releasing factor on anoxia-induced changes in evoked potentials in living slices of rat olfactory cortex.
Topics: Action Potentials; Animals; Corticotropin-Releasing Hormone; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; Hypoxia; Olfactory Pathways; Organ Culture Techniques; Oxygen; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Valine | 2004 |
Dendritic sodium spikelets and low-threshold calcium spikes in turtle olfactory bulb granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channel Blockers; Dendrites; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Mibefradil; Models, Neurological; Neurons; Nickel; Olfactory Bulb; Patch-Clamp Techniques; Pyridazines; Sodium; Synaptic Transmission; Tetrodotoxin; Time Factors; Turtles; Valine | 2005 |
Long-term potentiation in the optic tectum of rainbow trout.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Cadmium Chloride; Calcium; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Oncorhynchus mykiss; Superior Colliculi; Tetrodotoxin; Time Factors; Valine | 2004 |
NMDA receptor-dependent long-term potentiation in the telencephalon of the zebrafish.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channel Blockers; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Magnesium; Nifedipine; Potassium Chloride; Receptors, N-Methyl-D-Aspartate; Telencephalon; Time Factors; Valine; Zebrafish | 2004 |
Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Animals; Baculoviridae; Biophysics; Brain; Cells, Cultured; Chromatography, Gel; Dendritic Spines; Discs Large Homolog 1 Protein; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Genetic Vectors; Guanylate Kinases; Humans; Immunohistochemistry; In Vitro Techniques; Insecta; Intracellular Signaling Peptides and Proteins; Lentivirus; Long-Term Potentiation; Membrane Proteins; Mice; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Energy-Filtering Transmission Electron; Mutagenesis; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Receptors, AMPA; Recombinant Fusion Proteins; RNA, Antisense; RNA, Small Interfering; Sequence Alignment; Synapses; Synaptic Transmission; Time Factors; Transfection; Valine | 2004 |
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
Topics: Animals; Bicuculline; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Ionophores; Membrane Potentials; Microscopy, Electron, Transmission; Models, Neurological; Neural Inhibition; Neurons; Nystatin; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Presynaptic Terminals; Pyridines; Quinoxalines; Retina; Time Factors; Valine | 2004 |
Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons.
Topics: Analysis of Variance; Animals; Bicuculline; Blotting, Western; Cyclic Nucleotide-Gated Cation Channels; Dendrites; Electroencephalography; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Immunohistochemistry; In Vitro Techniques; Ion Channels; Kainic Acid; Male; Membrane Potentials; Muscle Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Seizures; Valine | 2004 |
Protective effect of rhynchophylline and isorhynchophylline on in vitro ischemia-induced neuronal damage in the hippocampus: putative neurotransmitter receptors involved in their action.
Topics: Alkaloids; Animals; Brain Ischemia; Cell Hypoxia; Hippocampus; In Vitro Techniques; Indole Alkaloids; Ketanserin; Male; Membrane Potentials; Neurons; Oocytes; Oxindoles; Pirenzepine; Rats; Rats, Wistar; Uncaria; Valine; Xenopus laevis | 2004 |
The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals.
Topics: Alkanes; Animals; Bicuculline; Bungarotoxins; Chromatography, High Pressure Liquid; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Linoleic Acid; Lysine; Male; Maleimides; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Receptors, Presynaptic; Synaptic Transmission; Valine | 2005 |
Synaptic physiology in the cochlear nucleus angularis of the chick.
Topics: Age Factors; Animals; Bicuculline; Chick Embryo; Cochlear Nerve; Cochlear Nucleus; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine Agents; Immunohistochemistry; In Vitro Techniques; Kinetics; Kv1.2 Potassium Channel; Neurons; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Quinoxalines; Reaction Time; Strychnine; Synapses; Synaptic Transmission; Valine | 2005 |
Two intra-amygdaloid pathways to the central amygdala exhibit different mechanisms of long-term potentiation.
Topics: Amygdala; Animals; Calcium Channel Blockers; Central Nervous System Stimulants; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; Male; Neural Pathways; Neurons; Nimodipine; Picrotoxin; Rats; Valine | 2005 |
Activity dependence of cortical axon branch formation: a morphological and electrophysiological study using organotypic slice cultures.
Topics: Action Potentials; Animals; Axons; Cerebral Cortex; Electroporation; Luminescent Proteins; Microelectrodes; Microscopy, Confocal; Neocortex; Neurons; Occipital Lobe; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tetrodotoxin; Tissue Culture Techniques; Valine | 2005 |
Beta-Amyloid peptide25-35 depresses excitatory synaptic transmission in the rat basolateral amygdala "in vitro".
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Amygdala; Amyloid beta-Peptides; Anesthetics, Local; Animals; Bicuculline; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Elapid Venoms; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Neurons; Nicotinic Antagonists; Nifedipine; Peptide Fragments; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin; Valine | 2005 |
Activity-dependent maturation of excitatory synaptic connections in solitary neuron cultures of mouse neocortex.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Neocortex; Neurons; Pyridinium Compounds; Quaternary Ammonium Compounds; Quinoxalines; Statistics, Nonparametric; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2005 |
GluR- and TrkB-mediated maturation of GABA receptor function during the period of eye opening.
Topics: Age Factors; Animals; Animals, Newborn; Blotting, Northern; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Embryo, Mammalian; Eye; GABA Agonists; Gene Expression Regulation, Developmental; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; Receptor, trkB; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superior Colliculi; Synapses; Synaptic Transmission; Valine; Zolpidem | 2005 |
Intraglomerular inhibition: signaling mechanisms of an olfactory microcircuit.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Bicuculline; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Dendrites; Diagnostic Imaging; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neural Conduction; Neural Inhibition; Neural Networks, Computer; Neurons; Nickel; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phosphinic Acids; Potassium; Propanolamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2005 |
Kv1 K+ channels control Purkinje cell output to facilitate postsynaptic rebound discharge in deep cerebellar neurons.
Topics: Action Potentials; Animals; Calcium Signaling; Cerebellum; Dendrites; Elapid Venoms; Electric Stimulation; Excitatory Postsynaptic Potentials; Ion Transport; Male; Neurotoxins; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Potassium; Potassium Channel Blockers; Potassium Channels; Propanolamines; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Shaker Superfamily of Potassium Channels; Sodium; Tetrodotoxin; Valine | 2005 |
5-HT1B receptor-mediated presynaptic inhibition of GABA release in the suprachiasmatic nucleus.
Topics: Animals; Bicuculline; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Knockout; Neural Inhibition; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Pyridines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Serotonin Receptor Agonists; Suprachiasmatic Nucleus; Tetrodotoxin; Time Factors; Valine | 2005 |
The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Western; Brain; Calcium; Cell Line; Cell Size; Cloning, Molecular; Dendritic Spines; DNA-Binding Proteins; Drug Interactions; Egtazic Acid; Ephrin-B1; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Humans; Immunohistochemistry; Immunoprecipitation; Microscopy, Immunoelectron; Models, Neurological; Neoplasm Proteins; Neurons; p21-Activated Kinases; Protein Serine-Threonine Kinases; Proteins; rac1 GTP-Binding Protein; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Antisense; RNA, Small Interfering; Synaptosomes; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Tetrodotoxin; Time Factors; Transcription Factors; Transfection; Valine | 2005 |
Single cell analysis of activity-dependent cyclic AMP-responsive element-binding protein phosphorylation during long-lasting long-term potentiation in area CA1 of mature rat hippocampal-organotypic cultures.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Colforsin; Cyclic AMP Response Element-Binding Protein; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Immunohistochemistry; In Vitro Techniques; Long-Term Potentiation; Male; Microscopy, Confocal; Neurons; Phosphorylation; Rats; Serine; Time Factors; Valine | 2005 |
Maturation of cultured hippocampal slices results in increased excitability in granule cells.
Topics: Animals; Animals, Newborn; Cellular Senescence; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Lysine; Neural Networks, Computer; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors; Valine | 2005 |
Drosophila mushroom body Kenyon cells generate spontaneous calcium transients mediated by PLTX-sensitive calcium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Analysis of Variance; Animals; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Chlorine; Cobalt; Curare; Diagnostic Imaging; Dose-Response Relationship, Radiation; Drosophila; Drug Combinations; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Iodine; Mushroom Bodies; Neurons; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Phenols; Picrotoxin; Pupa; Salicylates; Spider Venoms; Tetrodotoxin; Thapsigargin; Time Factors; Valine | 2005 |
Augmented prefrontal acetylcholine release during challenged attentional performance.
Topics: Acetylcholine; Adaptation, Physiological; Animals; Attention; Behavior, Animal; Male; Prefrontal Cortex; Psychomotor Performance; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2006 |
Dissection of bidirectional synaptic plasticity into saturable unidirectional processes.
Topics: Animals; Animals, Newborn; Carbazoles; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hippocampus; In Vitro Techniques; Indole Alkaloids; Lissamine Green Dyes; Long-Term Potentiation; Long-Term Synaptic Depression; Models, Biological; Neuronal Plasticity; Okadaic Acid; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Theta Rhythm; Time Factors; Valine | 2005 |
Learning twice is different from learning once and from learning more.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzylamines; Corpus Striatum; Dichlororibofuranosylbenzimidazole; Electroshock; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Hippocampus; Learning; Male; Maze Learning; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Retention, Psychology; Statistics, Nonparametric; Sulfonamides; Time Factors; Valine | 2005 |
Differences between cation-chloride co-transporter functions in the visual cortex of pigmented and albino rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Bumetanide; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Female; Furosemide; GABA Antagonists; Gramicidin; In Vitro Techniques; K Cl- Cotransporters; Male; Membrane Potentials; Models, Neurological; Neural Inhibition; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Long-Evans; Rats, Wistar; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Species Specificity; Symporters; Valine; Visual Cortex | 2005 |
D-serine enhances impaired long-term potentiation in CA1 subfield of hippocampal slices from aged senescence-accelerated mouse prone/8.
Topics: Age Factors; Aging; Analysis of Variance; Animals; D-Amino-Acid Oxidase; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Mice; Mice, Neurologic Mutants; Serine; Valine | 2005 |
GABAB receptors in the medial septum/diagonal band slice from 16-25 day rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-A; Septum Pellucidum; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2005 |
Kinetics and subunit composition of NMDA receptors in respiratory-related neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Northern; Brain Stem; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Respiration; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Valine | 2005 |
Integrin signaling cascades are operational in adult hippocampal synapses and modulate NMDA receptor physiology.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Western; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Hippocampus; In Vitro Techniques; Integrins; Male; Microscopy, Electron, Transmission; Neurons; Oligopeptides; Oligoribonucleotides, Antisense; Patch-Clamp Techniques; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Synapses; Synaptosomes; Time Factors; Valine | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
Sulfhydryl oxidation reduces hippocampal susceptibility to hypoxia-induced spreading depression by activating BK channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aniline Compounds; Animals; Calcium; Charybdotoxin; Cortical Spreading Depression; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamine; Hippocampus; Hypoxia; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Neurons; Nickel; Oxidation-Reduction; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Tolbutamide; Valine; Xanthenes | 2005 |
Hippocalcin-deficient mice display a defect in cAMP response element-binding protein activation associated with impaired spatial and associative memory.
Topics: Animals; Association Learning; Avoidance Learning; Behavior, Animal; Blotting, Western; Brain; Cadmium Chloride; Calcium Channel Blockers; Calcium-Binding Proteins; Choice Behavior; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Discrimination Learning; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavonoids; Hippocalcin; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Knockout; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Nimodipine; Phosphorylation; Potassium Chloride; Psychomotor Performance; Reaction Time; Rotarod Performance Test; Spatial Behavior; Valine | 2005 |
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.
Topics: Animals; Blotting, Western; Depression; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neuronal Plasticity; Quinoxalines; Receptor, Nerve Growth Factor; Receptors, AMPA; Receptors, Nerve Growth Factor; Signal Transduction; Synaptic Transmission; Valine | 2005 |
BDNF-induced facilitation of afferent-evoked responses in lamina II neurons is reduced after neonatal spinal cord contusion injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lamin Type B; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Valine | 2005 |
Chronic intermittent ethanol exposure enhances NMDA-receptor-mediated synaptic responses and NMDA receptor expression in hippocampal CA1 region.
Topics: Animals; Blotting, Western; Body Weight; Brain; Central Nervous System Depressants; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Organ Size; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors; Valine | 2005 |
Blockade of NMDA receptors enhances spontaneous sharp waves in rat hippocampal slices.
Topics: Animals; Apamin; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scorpion Venoms; Valine | 2005 |
Peripheral NMDA receptor modulation of jaw muscle electromyographic activity induced by capsaicin injection into the temporomandibular joint of rats.
Topics: Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Facial Pain; Inflammation; Jaw; Male; Muscle, Skeletal; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Valine | 2005 |
Gliotoxicity in hippocampal cultures is induced by transportable, but not by nontransportable, glutamate uptake inhibitors.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Death; Cells, Cultured; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Neuroglia; Neurons; Neurotoxins; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Dendritic Spines; Diagnostic Imaging; Dose-Response Relationship, Radiation; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Lasers; Membrane Potentials; Models, Neurological; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2005 |
Rap2-JNK removes synaptic AMPA receptors during depotentiation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Long-Term Synaptic Depression; Magnesium; Models, Neurological; Mutagenesis; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; rap GTP-Binding Proteins; Rats; Receptors, AMPA; Recombinant Proteins; Synaptic Transmission; Time Factors; Transfection; Valine | 2005 |
Hypoxia recruits a respiratory-related excitatory pathway to brainstem premotor cardiac vagal neurons in animals exposed to prenatal nicotine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Brain Stem; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine Agents; Hypoxia; Neural Pathways; Neurons; Nicotine; Nicotinic Agonists; Picrotoxin; Rats; Rats, Sprague-Dawley; Respiration; Strychnine; Valine | 2005 |
Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit.
Topics: 4-Aminopyridine; Animals; Bicuculline; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Deletion; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Mice; Mice, Knockout; Phosphinic Acids; Potassium Channel Blockers; Propanolamines; Pyramidal Cells; Quinolinium Compounds; Receptors, GABA-B; Time Factors; Valine | 2005 |
Calcium-stimulated adenylyl cyclases required for long-term potentiation in the anterior cingulate cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenine; Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Gyrus Cinguli; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nifedipine; Patch-Clamp Techniques; Picrotoxin; Synaptic Transmission; Time Factors; Valine | 2005 |
Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro.
Topics: Adenosine; Adenosine Deaminase; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Emodin; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Valine | 2005 |
AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Biotinylation; Blotting, Western; Brain; Brefeldin A; Calcium Channel Blockers; Cell Adhesion; Cells, Cultured; Chlorocebus aethiops; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Glycine; In Vitro Techniques; Integrin alphaVbeta3; Mitogen-Activated Protein Kinase Kinases; Neurons; Nifedipine; Paxillin; Phenanthridines; Phosphoproteins; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Quinoxalines; Rats; Receptors, AMPA; src-Family Kinases; Time Factors; Transfection; Valine | 2005 |
Effects of glutamate transporter and receptor ligands on neuronal glutamate uptake.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ligands; N-Methylaspartate; Naphthalenes; Neurons; Neuroprotective Agents; Oxepins; Rats; Rats, Wistar; Receptors, Glutamate; Tritium; Valine | 2005 |
Selective sparing of hippocampal CA3 cells following in vitro ischemia is due to selective inhibition by acidosis.
Topics: Acidosis; Animals; Animals, Newborn; Calcium; Cell Death; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Hydrogen-Ion Concentration; Ischemia; Mice; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Time Factors; Valine | 2005 |
Frequency-dependent impairment of hippocampal LTP from NMDA receptors with reduced calcium permeability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Integrases; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Effects of agonists and antagonists of NMDA and ACh receptors on plasticity of bat auditory system elicited by fear conditioning.
Topics: Acetylcholine; Acoustic Stimulation; Action Potentials; Animals; Atropine; Auditory Cortex; Auditory Pathways; Chiroptera; Cholinergic Agonists; Cholinergic Antagonists; Drug Interactions; Electric Stimulation; Fear; Inferior Colliculi; N-Methylaspartate; Neuronal Plasticity; Time Factors; Valine | 2005 |
In vivo calcium imaging of circuit activity in cerebellar cortex.
Topics: Animals; Animals, Newborn; Brain Mapping; Calcium; Cerebellar Cortex; Dendrites; Diagnostic Imaging; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Nerve Net; Neurons; Poloxamer; Quinoxalines; Rats; Rats, Wistar; Valine | 2005 |
Role of AMPA receptor desensitization and the side effects of a DMSO vehicle on reticulospinal EPSPs and locomotor activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Benzothiadiazines; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Lampreys; Motor Activity; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Neurons; Receptors, AMPA; Spinal Cord; Synapses; Valine | 2005 |
Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultured; Electric Impedance; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus, Anterior; Immunohistochemistry; Isoenzymes; Membrane Potentials; Mice; Microtubule-Associated Proteins; Muscimol; Neural Inhibition; Neurons; Nimodipine; Patch-Clamp Techniques; Pyrimidines; Receptors, AMPA; Sodium; Sodium Channel Blockers; Temperature; Tetrodotoxin; Valine | 2005 |
Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction.
Topics: Acetylcholinesterase; Aconitine; Animals; Animals, Newborn; Antibodies, Monoclonal; Cholinergic Fibers; Denervation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Immunotoxins; In Vitro Techniques; Long-Term Potentiation; N-Glycosyl Hydrolases; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Receptors, Nicotinic; Ribosome Inactivating Proteins, Type 1; Saporins; Valine | 2005 |
Effects of brain-derived neurotrophic factor (BDNF) on activity mediated by NMDA receptors in rat spinal cord cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Local; Animals; Antibodies; Brain-Derived Neurotrophic Factor; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neural Inhibition; Neurons; Organ Culture Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin; Valine | 2005 |
Glucocorticoid receptor activation selectively hampers N-methyl-D-aspartate receptor dependent hippocampal synaptic plasticity in vitro.
Topics: Animals; Calcium Channel Blockers; Corticosterone; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Hormone Antagonists; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mifepristone; Neuronal Plasticity; Nifedipine; Patch-Clamp Techniques; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Electrophysiological properties of human hypothalamic hamartomas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Bicuculline; Cadmium Chloride; Child; Child, Preschool; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Glutamic Acid; Hamartoma; Humans; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Infant; Isoenzymes; Kainic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periodicity; Phosphopyruvate Hydratase; Potassium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Valine | 2005 |
BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo.
Topics: Animals; Axons; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Green Fluorescent Proteins; Larva; Microscopy, Electron, Transmission; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Superior Colliculi; Synapses; Valine; Vesicle-Associated Membrane Protein 2; Xenopus laevis | 2005 |
The contribution of NMDA receptors in the dorsolateral striatum to egocentric response learning.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corpus Striatum; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Maze Learning; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Reversal Learning; Space Perception; Valine | 2005 |
Cooperative glutamatergic and cholinergic mechanisms generate short-term modifications of synaptic effectiveness in prepositus hypoglossi neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Animals, Newborn; Atropine; Brain Stem; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Muscarinic Antagonists; Nerve Net; Neurons; Patch-Clamp Techniques; Pirenzepine; Rats; Synaptic Transmission; Time Factors; Valine | 2005 |
NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feeding Behavior; Hypothalamus; Kynurenic Acid; Male; Microinjections; Neurons; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Satiety Response; Statistics, Nonparametric; Valine | 2005 |
Excitatory amino acid receptors are involved in morphine-induced synchronous oscillatory discharges in the locus coeruleus of rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Evoked Potentials; Injections, Intraventricular; Kynurenic Acid; Locus Coeruleus; Male; Morphine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Depression of extra-cellular GABA and increase of NMDA-induced nitric oxide following acute intra-nuclear administration of alcohol in the cerebellar nuclei of the rat.
Topics: Animals; Central Nervous System Depressants; Cerebellar Nuclei; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Agonists; gamma-Aminobutyric Acid; Indazoles; Injections, Intraventricular; Male; Microdialysis; N-Methylaspartate; Nipecotic Acids; Nitric Oxide; Quinoxalines; Rats; Rats, Wistar; Tiagabine; Valine | 2005 |
Dendrites contain a spacing pattern.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cells, Cultured; Cerebellum; Dendrites; Diffusion; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Mice; Microtubule-Associated Proteins; Microtubules; Morphogenesis; Neocortex; Neurons; Nocodazole; Paclitaxel; Potassium Chloride; Pyramidal Cells; Rats; Sodium Channel Blockers; Staining and Labeling; Tetrodotoxin; Valine | 2006 |
High content kinetic assays of neuronal signaling implemented on BD pathway HT.
Topics: Amyloid beta-Protein Precursor; Animals; Automation; Bicuculline; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Preclinical; Embryo, Mammalian; Fluorescent Dyes; GABA Antagonists; Humans; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Receptors, N-Methyl-D-Aspartate; Reproducibility of Results; Valine | 2005 |
Effect of NMDA antagonists on the death of cerebellar granule neurons at different ages.
Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; Carbachol; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cholinergic Agonists; Dizocilpine Maleate; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2006 |
NMDA-induced preconditioning attenuates synaptic plasticity in the rat hippocampus.
Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Neurons; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Valine; Xanthines | 2006 |
cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bacterial Proteins; Blotting, Western; Calcineurin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dendrites; Disks Large Homolog 4 Protein; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Long-Term Synaptic Depression; Luminescent Proteins; Male; Membrane Proteins; Mutagenesis; N-Methylaspartate; Neurons; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Time Factors; Transfection; Valine | 2006 |
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Topics: Age Factors; Animals; Biomarkers; Calpain; Dipeptides; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gene Expression Regulation, Developmental; Glucose; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Membrane Proteins; N-Methylaspartate; Neurons; Oxygen; Phenols; Piperidines; Propidium; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrin; Valine | 2006 |
Impaired feedforward inhibition of the thalamocortical projection in epileptic Ca2+ channel mutant mice, tottering.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Evoked Potentials; Excitatory Postsynaptic Potentials; Homeostasis; Lidocaine; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Somatosensory Cortex; Synaptic Transmission; Thalamic Nuclei; Valine | 2006 |
Long-lasting spontaneous calcium transients in the striatal cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Calcium; Chi-Square Distribution; Corpus Striatum; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fura-2; In Vitro Techniques; Neurons; Rats; Thapsigargin; Time Factors; Valine | 2006 |
Aversive learning under different training conditions: effects of NMDA receptor blockade in area CA1 of the hippocampus.
Topics: Animals; Behavior, Animal; Hippocampus; Learning; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Valine | 2006 |
Zinc modulates bidirectional hippocampal plasticity by effects on NMDA receptors.
Topics: Animals; Chelating Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Organ Culture Techniques; Phenanthrolines; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine; Zinc | 2006 |
Spontaneous field potentials in the glomeruli of the olfactory bulb: the leading role of juxtaglomerular cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; In Vitro Techniques; Male; Models, Neurological; Nerve Net; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Valine | 2006 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
BDNF up-regulates alpha7 nicotinic acetylcholine receptor levels on subpopulations of hippocampal interneurons.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cells, Cultured; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Interneurons; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Time Factors; Up-Regulation; Valine | 2006 |
Blocking L-type calcium channels enhances long-term depression induced by low-frequency stimulation at hippocampal CA1 synapses.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Male; Neurons; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Wistar; Synapses; Thapsigargin; Valine | 2006 |
Morphological constraints on calcium dependent glutamate receptor trafficking into individual dendritic spine.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Dendritic Spines; Fluorescence; Long-Term Potentiation; Neuronal Plasticity; Protein Transport; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thiazolidines; Valine | 2007 |
Platelet-activating factor contributes to the induction of long-term potentiation in the rat somatosensory cortex in vitro.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Agonists; In Vitro Techniques; Long-Term Potentiation; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Valine | 2007 |
Modulation of isolated N-methyl-d-aspartate receptor response under hyperbaric conditions.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Helium; High Pressure Neurological Syndrome; Hippocampus; In Vitro Techniques; Magnesium; Male; Pressure; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2006 |
Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines.
Topics: Actins; Animals; Animals, Newborn; Cell Survival; Central Nervous System Depressants; Dendritic Spines; Disks Large Homolog 4 Protein; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocrateaceae; Homeostasis; Hypoglycemic Agents; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Confocal; N-Methylaspartate; Neurons; Palmitates; Rats; Synapsins; Valine | 2006 |
Response profiles to amino acid odorants of olfactory glomeruli in larval Xenopus laevis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Calcium; Calcium Signaling; Excitatory Amino Acid Antagonists; In Vitro Techniques; Larva; Microscopy, Confocal; Olfactory Bulb; Olfactory Mucosa; Olfactory Pathways; Olfactory Receptor Neurons; Receptors, Odorant; Smell; Time Factors; Valine; Xenopus laevis | 2007 |
Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant.
Topics: Animals; Basal Ganglia; Caudate Nucleus; Cricetinae; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Microinjections; Movement; Muscle Contraction; Mutation; Posture; Putamen; Pyrrolidinones; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Valine | 2007 |
Endogenous GABA and glutamate finely tune the bursting of olfactory bulb external tufted cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Isonicotinic Acids; Male; Neurons; Olfactory Bulb; Pyridazines; Rats; Rats, Sprague-Dawley; Valine | 2007 |
Hepatocyte growth factor-induced enhancement of dendritic branching is blocked by inhibitors of N-methyl-D-aspartate receptors and calcium/calmodulin-dependent kinases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Dendrites; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hepatocyte Growth Factor; Hippocampus; Immunohistochemistry; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2007 |
D-Serine inhibits AMPA receptor-mediated current in rat hippocampal neurons.
Topics: Action Potentials; Amino Acids; Aminobutyrates; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Molecular Structure; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Valine | 2007 |
Pharmacological analysis of excitatory and inhibitory synaptic transmission in horizontal brainstem slices preserving three subnuclei of spinal trigeminal nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses; Trigeminal Nucleus, Spinal; Valine | 2008 |
The effect of the NMDA receptor antagonist MK-801 on the acquisition and extinction of learned fear in the developing rat.
Topics: Age Factors; Animals; Avoidance Learning; Conditioning, Classical; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2007 |
Effects of chronic network hyperexcitability on the growth of hippocampal dendrites.
Topics: Analysis of Variance; Animals; Bicuculline; Convulsants; CREB-Binding Protein; Dendrites; Drug Interactions; Hippocampus; Luminescent Proteins; Mice; Mice, Transgenic; Nerve Net; Neurons; Patch-Clamp Techniques; Thy-1 Antigens; Valine | 2008 |
The slow afterhyperpolarization modulates high pH-induced changes in the excitability of rat CA1 pyramidal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Neurotransmitter Agents; Pyramidal Cells; Rats; Rats, Wistar; Valine | 2007 |
Learning-induced modulation of SK channels-mediated effect on synaptic transmission.
Topics: Analysis of Variance; Animals; Apamin; Behavior, Animal; Brain; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Learning; Male; Membrane Potentials; Patch-Clamp Techniques; Random Allocation; Rats; Rats, Sprague-Dawley; Small-Conductance Calcium-Activated Potassium Channels; Synaptic Transmission; Valine; Water Deprivation | 2007 |
Recruiting extrasynaptic NMDA receptors augments synaptic signaling.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Dendrites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Neurons; Organic Chemicals; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin; Valine | 2008 |
Recruitment of excitatory serotonergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus post hypoxia and hypercapnia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Animals, Newborn; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hypercapnia; Hypoxia; In Vitro Techniques; Neurons; Nucleus Accumbens; Ondansetron; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Respiration; Serotonin; Serotonin Antagonists; Vagus Nerve; Valine | 2008 |
Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Electric Stimulation; Ephrins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Long-Term Potentiation; Microscopy, Electron, Transmission; Neuronal Plasticity; Patch-Clamp Techniques; Peptide Fragments; Retinal Ganglion Cells; Signal Transduction; Superior Colliculi; Synapses; Synaptic Transmission; Synaptosomal-Associated Protein 25; Time Factors; Valine; Xenopus laevis | 2008 |
GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
Topics: Age Factors; Animals; Animals, Newborn; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Rats; Rats, Wistar; Valine | 2008 |
Distinct single but not necessarily repeated tetanization is required to induce hippocampal late-LTP in the rat CA1.
Topics: Animals; Anisomycin; Benzazepines; Dopamine Antagonists; Electric Stimulation; Emetine; Hippocampus; In Vitro Techniques; Learning; Long-Term Potentiation; Male; Memory; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D5; Receptors, N-Methyl-D-Aspartate; Synapses; Valine | 2008 |
Global evaluation of contributions of GABA A, AMPA and NMDA receptors to orientation maps in cat's visual cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Brain Mapping; Cats; GABA Antagonists; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Valine; Visual Cortex | 2008 |
Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury.
Topics: Animals; Astrocytes; Brain Injuries; CD11b Antigen; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Ion Channels; Kynurenic Acid; Male; Microglia; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Sodium Channel Blockers; Time Factors; Treatment Outcome; Up-Regulation; Valine | 2008 |
Presynaptic modulation by somatostatin in the neostriatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Somatostatin; Valine | 2008 |
Transient disruption of fear-related memory by post-retrieval inactivation of gastrin-releasing peptide or N-methyl-D-aspartate receptors in the hippocampus.
Topics: Analysis of Variance; Animals; Avoidance Learning; Bombesin; Excitatory Amino Acid Antagonists; Fear; Gastrin-Releasing Peptide; Hippocampus; Male; Mental Recall; Peptide Fragments; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2008 |
Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated alpha7 nicotinic receptor gene transfer.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Animals, Newborn; Dependovirus; Drug Interactions; Excitatory Amino Acid Antagonists; Gene Transfer Techniques; Hippocampus; In Vitro Techniques; Indoles; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sodium Channel Blockers; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 2008 |
Rapid synaptic scaling induced by changes in postsynaptic firing.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Bacterial Proteins; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Excitatory Amino Acid Antagonists; Hydrogen-Ion Concentration; Luminescent Proteins; Neurons; Nickel; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Transfection; Valine | 2008 |
Endocannabinoids mediate neuron-astrocyte communication.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Calcium; Cannabinoid Receptor Modulators; Cell Communication; Egtazic Acid; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Photolysis; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Type C Phospholipases; Valine | 2008 |
Morphine withdrawal affects both delayed-escape behaviour in Morris water maze and hippocampal NR2A/2B expression ratio.
Topics: Analysis of Variance; Animals; Behavior, Animal; Conditioning, Operant; Escape Reaction; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Morphine; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Time Factors; Valine | 2008 |
The role of NMDA receptors in regulating group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex.
Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2008 |
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine | 2008 |
Altered dendritic integration in hippocampal granule cells of spatial learning-impaired aged rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Analysis of Variance; Animals; Behavior, Animal; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Reaction Time; Space Perception; Valine | 2008 |
Synaptic commitment: developmentally regulated reciprocal changes in hippocampal granule cell NMDA and AMPA receptors over the lifespan.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Swimming; Synapses; Time Factors; Valine | 2008 |
Spike timing-dependent long-term potentiation in ventral tegmental area dopamine cells requires PKC.
Topics: Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Phorbol Esters; Protein Kinase C; Time Factors; Valine; Ventral Tegmental Area | 2008 |
Postsynaptic action of brain-derived neurotrophic factor attenuates alpha7 nicotinic acetylcholine receptor-mediated responses in hippocampal interneurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Bungarotoxins; Chelating Agents; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Interneurons; Male; Patch-Clamp Techniques; Protein Kinase Inhibitors; Pyrimidines; Rats; Receptors, Nicotinic; Sodium Channel Blockers; Tetrodotoxin; Triazoles; Valine | 2008 |
Excitatory GABA in rodent developing neocortex in vitro.
Topics: Age Factors; Animals; Animals, Newborn; Bumetanide; Excitatory Amino Acid Antagonists; Female; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Lysine; Male; Membrane Potentials; Mice; Models, Neurological; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Sodium Potassium Chloride Symporter Inhibitors; Valine | 2008 |
Silencing-induced metaplasticity in hippocampal cultured neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Analysis of Variance; Animals; Calcium Channel Blockers; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Mice; Mice, Inbred C57BL; Neural Inhibition; Neuronal Plasticity; Neurons; Nifedipine; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2008 |
Estradiol-induced enhancement of object memory consolidation involves NMDA receptors and protein kinase A in the dorsal hippocampus of female C57BL/6 mice.
Topics: Animals; Behavior, Animal; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Estradiol; Estrogens; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Memory; Mice; Mice, Inbred C57BL; Ovariectomy; Pattern Recognition, Visual; Photic Stimulation; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; Thionucleotides; Valine | 2008 |
Spike timing-dependent long-term depression requires presynaptic NMDA receptors.
Topics: Action Potentials; Animals; Animals, Newborn; Dizocilpine Maleate; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Presynaptic Terminals; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Valine | 2008 |
Formation and maintenance of ventilatory long-term facilitation require NMDA but not non-NMDA receptors in awake rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Heart Rate; Hypoxia; Long-Term Potentiation; Male; Motor Neurons; Neural Pathways; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Respiratory Muscles; Tidal Volume; Time Factors; Valine; Wakefulness | 2008 |
AMPA receptor-dependent H2O2 generation in striatal medium spiny neurons but not dopamine axons: one source of a retrograde signal that can inhibit dopamine release.
Topics: Analysis of Variance; Animals; Axons; Benzodiazepines; Catalase; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Electric Stimulation; Excitatory Amino Acid Antagonists; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Neural Pathways; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Thiomalates; Tyrosine 3-Monooxygenase; Valine | 2008 |
High potassium induces taurine release by osmosensitive and osmoresistant mechanisms in the rat hippocampus in vivo.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Hippocampus; Hypertonic Solutions; Male; Microdialysis; N-Methylaspartate; Potassium Chloride; Rats; Rats, Sprague-Dawley; Taurine; Valine; Water-Electrolyte Balance | 2009 |
Glutamate receptors on dopamine neurons control the persistence of cocaine seeking.
Topics: Animals; Behavior, Animal; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; Motor Activity; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine; Ventral Tegmental Area | 2008 |
Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microscopy, Electron, Scanning; N-Methylaspartate; Potassium Chloride; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium; Valine | 2008 |
BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Behavior, Animal; Calcium; Colforsin; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Synapses; Synaptic Transmission; Valine | 2008 |
Reassembling a system from the sensor to cerebral representation: the olfactory system in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Animals, Newborn; Axons; Bromodeoxyuridine; Calcium; Calcium-Binding Proteins; Cell Differentiation; Cell Proliferation; Coculture Techniques; Electric Stimulation; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Transgenic; Nerve Tissue Proteins; Olfactory Mucosa; Olfactory Pathways; Olfactory Receptor Neurons; Organ Culture Techniques; Time Factors; Valine | 2008 |
Neuronal activity and TrkB ligands influence Kv3.1b and Kv3.2 expression in developing cortical interneurons.
Topics: Action Potentials; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Interneurons; Magnesium; Nerve Growth Factors; Nerve Tissue Proteins; Organ Culture Techniques; Rats; Rats, Long-Evans; Receptor, trkB; RNA, Messenger; Shaw Potassium Channels; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine; Visual Cortex | 2008 |
Use of calcium imaging for analysis of neuronal gap junction coupling.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Anesthetics; Animals; Bicuculline; Calcium; Cells, Cultured; Connexins; CREB-Binding Protein; Diagnostic Imaging; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA Antagonists; Gap Junction delta-2 Protein; Gap Junctions; Glycyrrhetinic Acid; Halothane; Hypothalamus, Middle; Mice; Mice, Knockout; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2008 |
Behavioral state regulation of dendrodendritic synaptic inhibition in the olfactory bulb.
Topics: Anesthesia; Animals; Behavior, Animal; Cholinergic Antagonists; Dendrites; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Antagonists; Male; Models, Biological; Neural Inhibition; Neurons; Olfactory Bulb; Olfactory Pathways; Picrotoxin; Rats; Rats, Wistar; Scopolamine; Synapses; Synaptic Transmission; Valine; Wakefulness | 2008 |
Spatiotemporal profiles of field potentials in mouse superior colliculus analyzed by multichannel recording.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Electric Stimulation; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Neurons; Patch-Clamp Techniques; Spectrum Analysis; Superior Colliculi; Valine | 2008 |
Developmental switch in requirement for PKA RIIbeta in NMDA-receptor-dependent synaptic plasticity at Schaffer collateral to CA1 pyramidal cell synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Valine | 2009 |
AMPA silencing is a prerequisite for developmental long-term potentiation in the hippocampal CA1 region.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Animals, Newborn; Colforsin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Models, Biological; Rats; Valine; Xanthenes | 2008 |
Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Topics: Animals; Autoradiography; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guinea Pigs; In Vitro Techniques; Iodine Isotopes; Male; Membrane Potentials; Neurokinin B; Patch-Clamp Techniques; Peptide Fragments; Prefrontal Cortex; Protein Binding; Pyramidal Cells; Quinolines; Quinoxalines; Receptors, Neurokinin-3; Substance P; Valine | 2008 |
The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Conditioning, Classical; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fear; Hippocampus; In Vitro Techniques; Learning Disabilities; Long-Term Potentiation; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Nerve Growth Factors; Neuropeptides; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Valine | 2008 |
Alternating low frequency stimulation of medial septal and commissural fibers induces NMDA-dependent, long-lasting potentiation of hippocampal synapses in urethane-anesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Long-Evans; Scopolamine; Septum of Brain; Synapses; Urethane; Valine | 2009 |
Continuous shifts in the active set of spinal interneurons during changes in locomotor speed.
Topics: Action Potentials; Adaptation, Physiological; Animals; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Electronic Data Processing; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Interneurons; Larva; Motor Neurons; Movement; Nerve Net; Neural Inhibition; Patch-Clamp Techniques; Periodicity; Quinoxalines; Recruitment, Neurophysiological; Spinal Cord; Swimming; Synaptic Potentials; Valine; Zebrafish | 2008 |
NMDA receptor activation by HIV-Tat protein is clade dependent.
Topics: Amino Acid Motifs; Animals; Antibodies; Cells, Cultured; Cysteine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; Humans; Immunoprecipitation; Models, Molecular; Mutagenesis, Site-Directed; Neurons; Nitric Oxide Donors; Protein Binding; Rats; Receptors, N-Methyl-D-Aspartate; S-Nitrosoglutathione; Serine; tat Gene Products, Human Immunodeficiency Virus; Transfection; Valine | 2008 |
Abolishment of serotonergic neurotransmission to cardiac vagal neurons during and after hypoxia and hypercapnia with prenatal nicotine exposure.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Conotoxins; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agents; Female; Heart; Hypercapnia; Hypoxia; In Vitro Techniques; Male; Neurons; Nicotine; Nicotinic Antagonists; Ondansetron; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Serotonin; Serotonin Antagonists; Synaptic Transmission; Vagus Nerve; Valine | 2009 |
Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts.
Topics: Animals; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Disks Large Homolog 4 Protein; Hippocampus; Intracellular Signaling Peptides and Proteins; Iontophoresis; Membrane Potentials; Membrane Proteins; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Protein Binding; Rats; Receptors, AMPA; Synapses; Time Factors; Valine | 2008 |
Abnormal network activity in a targeted genetic model of human double cortex.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroporation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Humans; In Vitro Techniques; Malformations of Cortical Development; Membrane Potentials; Microtubule-Associated Proteins; Mutation; Nerve Net; Neurons; Neuropeptides; Pregnancy; Quinoxalines; Rats; Rats, Wistar; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways.
Topics: Animals; Arginine; Cannabinoid Receptor Modulators; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Dronabinol; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucocorticoids; Glutamic Acid; GTP-Binding Proteins; Guanosine Diphosphate; Hypothalamus; In Vitro Techniques; Male; Neurons; Nitric Oxide; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Piperidines; Pyrans; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Rimonabant; Signal Transduction; Synapses; Synaptic Transmission; Thionucleotides; Valine | 2009 |
Deficits in development of synaptic plasticity in rat dorsal striatum following prenatal and neonatal exposure to low-dose bisphenol A.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Benzazepines; Benzhydryl Compounds; Corpus Striatum; Dopamine Agonists; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Male; Neuronal Plasticity; Phenols; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Rats, Sprague-Dawley; Synapses; Valine | 2009 |
The contribution of synaptic inputs to sustained depolarizations in reticulospinal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Electric Stimulation; Electromyography; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; In Vitro Techniques; Larva; Lidocaine; Membrane Potentials; Neural Pathways; Neurons; Patch-Clamp Techniques; Petromyzon; Reticular Formation; Spinal Cord; Strychnine; Synapses; Time Factors; Trigeminal Nerve; Valine | 2009 |
Post-training infusion of glutamate into the bed nucleus of the stria terminalis enhanced inhibitory avoidance memory: an effect involving norepinephrine.
Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memory; Motor Activity; Norepinephrine; Propranolol; Rats; Rats, Wistar; Septal Nuclei; Valine | 2009 |
Homeostatic presynaptic suppression of neuronal network bursts.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Green Fluorescent Proteins; Hippocampus; Inhibitory Postsynaptic Potentials; Lidocaine; N-Methylaspartate; Nerve Net; Neurons; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptosomal-Associated Protein 25; Tetrodotoxin; Time Factors; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2009 |
Presynaptic muscarinic receptors enhance glutamate release at the mitral/tufted to granule cell dendrodendritic synapse in the rat main olfactory bulb.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Animals, Newborn; Biophysics; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Models, Biological; Muscarinic Antagonists; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Pirenzepine; Presynaptic Terminals; Rats; Receptors, Muscarinic; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
Neuregulin signaling is dispensable for NMDA- and GABA(A)-receptor expression in the cerebellum in vivo.
Topics: Animals; Animals, Newborn; Cerebellum; Electric Stimulation; Enzyme Inhibitors; ErbB Receptors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; Male; Mice; Mice, Knockout; Neuregulins; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Receptor, ErbB-2; Receptor, ErbB-4; Receptors, GABA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
NMDA receptor activation by spontaneous glutamatergic neurotransmission.
Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Miniature Postsynaptic Potentials; Neocortex; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2009 |
Synchronous GABA-receptor-dependent potentials in limbic areas of the in-vitro isolated adult guinea pig brain.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cortical Spreading Depression; Cortical Synchronization; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Guinea Pigs; Inhibitory Postsynaptic Potentials; Limbic System; Neurons; Olfactory Pathways; Organ Culture Techniques; Potassium Channel Blockers; Quinoxalines; Receptors, GABA; Valine | 2009 |
Cocaine-induced LTP in the ventral tegmental area: new insights into mechanism and time course illuminate the cellular substrates of addiction.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Long-Term Potentiation; Receptors, Dopamine D5; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine; Ventral Tegmental Area | 2009 |
Rapid plasticity at inhibitory and excitatory synapses in the hippocampus induced by ictal epileptiform discharges.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biophysics; Calcium; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-B Receptor Antagonists; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Magnesium; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuronal Plasticity; Potassium; Pyridazines; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2009 |
Prenatal ethanol exposure persistently impairs NMDA receptor-dependent activation of extracellular signal-regulated kinase in the mouse dentate gyrus.
Topics: Analysis of Variance; Animals; Butadienes; Dentate Gyrus; Dizocilpine Maleate; Embryo, Mammalian; Enzyme Activation; Ethanol; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Nitriles; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Valine | 2009 |
Rapid and sensitive mapping of long-range connections in vitro using flavoprotein autofluorescence imaging combined with laser photostimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Brain Mapping; Excitatory Amino Acid Antagonists; Female; Flavoproteins; Fourier Analysis; Glutamates; In Vitro Techniques; Lasers; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Neural Pathways; Patch-Clamp Techniques; Photic Stimulation; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Synapses; Thalamus; Time Factors; Valine | 2009 |
Subcellular topography of visually driven dendritic activity in the vertebrate visual system.
Topics: Action Potentials; Animals; Brain Mapping; Calcium; Calcium Signaling; Dendrites; Excitatory Amino Acid Antagonists; GABA Antagonists; Imaging, Three-Dimensional; Larva; Light; Microscopy, Confocal; Neurons; Photic Stimulation; Presynaptic Terminals; Pyridazines; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions; Valine; Visual Pathways; Xenopus | 2009 |
Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling.
Topics: Aniline Compounds; Animals; Animals, Newborn; Arachidonic Acids; Benzamides; Bicuculline; Biophysics; Calcium; Calcium Signaling; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Carbamates; Cerebellum; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluoresceins; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycerides; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lactones; Mice; Muscimol; Orlistat; Patch-Clamp Techniques; Piperidines; Purkinje Cells; Pyrazoles; Quinoxalines; Rimonabant; Signal Transduction; Synapses; Valine | 2009 |
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Movement; Cerebral Cortex; Electroporation; Embryo, Mammalian; Female; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Homeodomain Proteins; Interneurons; K Cl- Cotransporters; LIM-Homeodomain Proteins; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microtubule-Associated Proteins; Models, Biological; Muscimol; Nerve Tissue Proteins; Nifedipine; omega-Conotoxin GVIA; Organ Culture Techniques; Pregnancy; Quinoxalines; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sequence Deletion; Symporters; Transcription Factors; Valine | 2009 |
Synaptic and extrasynaptic factors governing glutamatergic retinal waves.
Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Aspartic Acid; Calcium; Dihydro-beta-Erythroidine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; N-Methylaspartate; Neural Inhibition; Nicotinic Antagonists; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2009 |
Severity of atypical absence phenotype in GABAB transgenic mice is subunit specific.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Autoradiography; Cognition Disorders; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Maze Learning; Mice; Mice, Transgenic; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Phenotype; Protein Binding; Receptors, GABA-B; Tritium; Valine | 2009 |
Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patterns.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Lidocaine; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Time Factors; Tubulin; Valine | 2009 |
Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.
Topics: 14-3-3 Proteins; Alanine; Animals; Biotinylation; Cell Line, Transformed; Cells, Cultured; Cerebellum; Dendrites; Excitatory Amino Acid Antagonists; Gene Expression; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Insulin-Like Growth Factor I; Luminescent Proteins; Mice; Mutation; N-Methylaspartate; Neurons; Oncogene Protein v-akt; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Transfection; Valine | 2009 |
Pretraining does not ameliorate spatial learning deficits induced by intrahippocampal infusion of AP5.
Topics: Analysis of Variance; Animals; Catheterization; Central Nervous System Agents; Hippocampus; Learning Disabilities; Male; Maze Learning; Microinjections; Practice, Psychological; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Space Perception; Swimming; Time Factors; Valine | 2009 |
Expression of glutamate receptor subunits in human cancers.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Brain; Cell Line, Tumor; Excitatory Amino Acid Antagonists; Humans; Neoplasms; Patch-Clamp Techniques; Protein Subunits; Receptors, AMPA; Receptors, Metabotropic Glutamate; Valine | 2009 |
Dopamine-deprived striatal GABAergic interneurons burst and generate repetitive gigantic IPSCs in medium spiny neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Animals; Biological Clocks; Biophysics; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lysine; Mice; Nicotine; Nicotinic Agonists; Oxidopamine; Patch-Clamp Techniques; Spectrum Analysis; Tyrosine 3-Monooxygenase; Valine | 2009 |
Serotonergic modulation of the trigeminocardiac reflex neurotransmission to cardiac vagal neurons in the nucleus ambiguus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Citalopram; Dipeptides; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Heart; In Vitro Techniques; Ketanserin; Neural Pathways; Neurons; Nucleus Accumbens; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Vagus Nerve; Valine | 2009 |
N-type calcium channels mediate a GABA(B) presynaptic modulation in the corticostriatal synapse in turtle's paleostriatum augmentatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Biophysics; Calcium Channel Blockers; Calcium Channels, N-Type; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Presynaptic Terminals; Receptors, GABA-B; Synapses; Turtles; Valine | 2009 |
Estradiol negative feedback regulation by glutamatergic afferents to A15 dopaminergic neurons: variation with season.
Topics: Animals; Estradiol; Excitatory Amino Acid Antagonists; Feedback, Physiological; Female; Luteinizing Hormone; Neurons, Afferent; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seasons; Sheep; Tyrosine 3-Monooxygenase; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Inhibitory Amino Acid Transport Proteins | 2009 |
Direct excitation of spinal GABAergic interneurons by noradrenaline.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic Agents; Adrenergic alpha-Agonists; Analysis of Variance; Anesthetics, Local; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Membrane Potentials; Mice; Mice, Transgenic; Norepinephrine; Patch-Clamp Techniques; Spinal Cord; Tetrodotoxin; Valine | 2009 |
Respiratory activity of the neonatal dorsolateral pons in vitro.
Topics: Animals; Animals, Newborn; Bicuculline; Brain Stem; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Functional Laterality; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Models, Biological; Neurons; Patch-Clamp Techniques; Pons; Rats; Respiratory Physiological Phenomena; Respiratory System; Spinal Cord; Valine | 2009 |
NMDA receptor blockage with 2-amino-5-phosphonovaleric acid improves oxidative stress after spinal cord trauma in rats.
Topics: Animals; Disease Models, Animal; Glutathione; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Superoxide Dismutase; Valine | 2010 |
A self-adapting approach for the detection of bursts and network bursts in neuronal cultures.
Topics: Action Potentials; Adaptation, Physiological; Algorithms; Animals; Bicuculline; Cells, Cultured; Cerebral Cortex; Computer Simulation; Electrodes; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Nerve Net; Neurons; Probability; Rats; Time Factors; Valine | 2010 |
Long-term potentiation in the rat medial vestibular nuclei depends on locally synthesized 17beta-estradiol.
Topics: Animals; Animals, Newborn; Aromatase Inhibitors; Bicuculline; Biophysics; Drug Interactions; Electric Stimulation; Estradiol; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Fulvestrant; GABA Antagonists; In Vitro Techniques; Letrozole; Long-Term Potentiation; Male; Nitriles; Quinoxalines; Rats; Rats, Wistar; Triazoles; Valine; Vestibular Nuclei | 2009 |
Effects of the NMDA receptor antagonists on deltamethrin-induced striatal dopamine release in conscious unrestrained rats.
Topics: Animals; Consciousness; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Insecticides; Male; Nitriles; Pyrethrins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2009 |
The dorsal periaqueductal gray modulates the increased fear-like behavior exhibited by experienced rats in the elevated plus-maze.
Topics: Analysis of Variance; Animals; Avoidance Learning; Catheters, Indwelling; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Injections, Intraventricular; Male; Maze Learning; Periaqueductal Gray; Piperidines; Rats; Rats, Wistar; Space Perception; Staining and Labeling; Valine | 2010 |
GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cells, Cultured; CREB-Binding Protein; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Lysine; Membrane Potentials; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Quinoxalines; Receptors, GABA-B; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2009 |
Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Biophysics; CA1 Region, Hippocampal; Cadmium Chloride; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lamotrigine; Lysine; Male; Neural Inhibition; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Quinoxalines; Rats; Rats, Long-Evans; Tetraethylammonium; Triazines; Valine | 2010 |
Tonic modulation of GABA release by nicotinic acetylcholine receptors in layer V of the murine prefrontal cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Choline O-Acetyltransferase; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lysine; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Receptors, Nicotinic; Valine; Vesicular Acetylcholine Transport Proteins | 2010 |
Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors.
Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Valine | 2010 |
Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; Chelating Agents; Disks Large Homolog 4 Protein; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Patch-Clamp Techniques; Posterior Horn Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synapses; Valine | 2009 |
Role of AMPA and NMDA receptors and back-propagating action potentials in spike timing-dependent plasticity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; CA1 Region, Hippocampal; Central Nervous System Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; Magnesium; Membrane Potentials; Neuronal Plasticity; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats contributes to the induction of persistent LTD via an adenosine-A1 receptor-regulated mechanism.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Biophysics; CA3 Region, Hippocampal; Cyclopropanes; Dihydropyridines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Synaptic Depression; Male; Mossy Fibers, Hippocampal; Rats; Rats, Wistar; Receptor, Adenosine A1; Statistics as Topic; Time Factors; Valine; Wakefulness; Xanthines; Xylenes | 2010 |
Optical tracking of phenotypically diverse individual synapses on solitary tract nucleus neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Capsaicin; Complex Mixtures; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kinetics; Male; Nerve Fibers, Myelinated; Neural Inhibition; Neurons; Neurons, Afferent; Optics and Photonics; Patch-Clamp Techniques; Potassium Chloride; Protein Transport; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Sensory System Agents; Solitary Nucleus; Synapses; Synaptic Transmission; Synaptophysin; Valine | 2010 |
Regulation of stargazin synaptic trafficking by C-terminal PDZ ligand phosphorylation in bidirectional synaptic plasticity.
Topics: Animals; Calcium Channels; Cells, Cultured; Chlorocebus aethiops; Cyclic AMP-Dependent Protein Kinases; Disks Large Homolog 4 Protein; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Hippocampus; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Long-Term Synaptic Depression; Membrane Proteins; Methoxyhydroxyphenylglycol; Mitogen-Activated Protein Kinases; Mutagenesis; Neuronal Plasticity; Neurons; PDZ Domains; Phosphorylation; Protein Transport; Rats; Threonine; Transfection; Valine | 2010 |
Nuclear calcium controls the apoptotic-like cell death induced by d-erythro-sphinganine in tobacco cells.
Topics: Active Transport, Cell Nucleus; Apoptosis; Calcium; Calcium Signaling; Cell Line; Cell Nucleus; Dizocilpine Maleate; Hydrolysis; Lanthanum; Nicotiana; Phosphotransferases (Alcohol Group Acceptor); Receptors, N-Methyl-D-Aspartate; Serine C-Palmitoyltransferase; Sphingosine; Valine | 2010 |
Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alcoholism; Amygdala; Animals; Body Weight; Central Nervous System Depressants; Corticotropin-Releasing Hormone; Cyclophilins; Ethanol; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hormone Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Microdialysis; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; RNA, Messenger; Time Factors; Valine | 2010 |
Embryonic striatal grafts restore bi-directional synaptic plasticity in a rodent model of Huntington's disease.
Topics: Animals; Biophysics; Chi-Square Distribution; Corpus Striatum; Disease Models, Animal; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Huntington Disease; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Recovery of Function; Synapses; Tissue Transplantation; Valine | 2009 |
Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anti-Anxiety Agents; Bicuculline; Cerebral Cortex; Cyclic Nucleotide-Gated Cation Channels; Desoxycorticosterone; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Agents; Homeostasis; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Patch-Clamp Techniques; Potassium Channels; Protein Subunits; Pyramidal Cells; Pyridazines; Pyrimidines; Receptors, GABA-A; Sodium Channel Blockers; Synapses; Tetrodotoxin; Up-Regulation; Valine | 2010 |
Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus.
Topics: Animals; Animals, Newborn; Benzoxazines; Cyclohexanones; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lipoprotein Lipase; Lysine; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Neocortex; Neural Inhibition; Neurons; Pyridazines; Quinoxalines; Receptor, Cannabinoid, CB1; Valine | 2010 |
Bidirectional synaptic plasticity in response to single or paired pulse activation of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Transient oxidative stress evokes early changes in the functional properties of neonatal rat hypoglossal motoneurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Activating Transcription Factor 3; Animals; Animals, Newborn; Bicuculline; Biophysics; Brain Stem; Cell Survival; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine Agents; Hydrogen Peroxide; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neurofilament Proteins; Oxidative Stress; Patch-Clamp Techniques; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium Channel Blockers; Statistics, Nonparametric; Strychnine; Tetrodotoxin; Thapsigargin; Valine | 2010 |
Intracellular calcium ion dynamics involved in long-term potentiation in hippocampal CA1 neurons in mice lacking the IP3 type 1 receptor.
Topics: Animals; Animals, Newborn; Biophysics; CA1 Region, Hippocampal; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Long-Term Potentiation; Mice; Mice, Knockout; Neurons; Valine | 2010 |
Opioid-induced long-term potentiation in the spinal cord is a presynaptic event.
Topics: Analgesics, Opioid; Animals; Biophysics; Calcium; Chelating Agents; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guanosine Diphosphate; In Vitro Techniques; Lectins; Long-Term Potentiation; Male; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spinal Cord; Thionucleotides; TRPV Cation Channels; Valine | 2010 |
Demonstration of a neural circuit critical for imprinting behavior in chicks.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Biotin; Brain Mapping; Cell Count; Cerebral Cortex; Chick Embryo; Chickens; Cholera Toxin; Dextrans; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Imprinting, Psychological; In Vitro Techniques; Nerve Net; Optic Nerve; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Rhodanine; RNA, Messenger; Thiazolidines; Valine; Vesicular Glutamate Transport Protein 2; Visual Pathways | 2010 |
Evidence for the persistence of contextual fear memories following immediate extinction.
Topics: Animals; Behavior, Animal; Biophysics; Conditioning, Classical; Electroshock; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2010 |
Indian red scorpion venom depresses spinal synaptic transmission without involving NMDA receptors.
Topics: Animals; Animals, Newborn; In Vitro Techniques; Motor Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Reflex; Scorpion Venoms; Spinal Cord; Synaptic Potentials; Synaptic Transmission; Valine | 2010 |
NMDAR-dependent control of call duration in Xenopus laevis.
Topics: Afferent Pathways; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Laryngeal Nerves; Medulla Oblongata; Neurons; Periodicity; Receptors, N-Methyl-D-Aspartate; Serotonin; Temperature; Time Factors; Valine; Vocalization, Animal; Xenopus laevis | 2010 |
Off-line concomitant release of dopamine and glutamate involvement in taste memory consolidation.
Topics: Amygdala; Animals; Avoidance Learning; Benzazepines; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Dopamine; Electrophoresis, Capillary; Glutamic Acid; Male; Memory; Microdialysis; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Taste; Valine | 2010 |
Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons.
Topics: Animals; Excitatory Postsynaptic Potentials; Inhibitory Postsynaptic Potentials; Male; N-Methylaspartate; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin; Valine; Xenon | 2010 |
Early APV chronic blocked alters experience-dependent plasticity of auditory spatial representation in rat auditory cortical neurons.
Topics: Acoustic Stimulation; Aging; Animals; Auditory Cortex; Auditory Perception; Drug Implants; Excitatory Amino Acid Antagonists; Microelectrodes; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Space Perception; Valine | 2010 |
Effects of pharmacological entopeduncular manipulations on idiopathic dystonia in the dt(sz) mutant hamster.
Topics: Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dystonia; Entopeduncular Nucleus; Excitatory Amino Acid Antagonists; GABA Agents; Microinjections; Muscimol; Nipecotic Acids; Oximes; Pentylenetetrazole; Quinoxalines; Reaction Time; Severity of Illness Index; Time Factors; Valine | 2010 |
Activation of NMDA receptors is necessary for the recovery of cortical binocularity.
Topics: Analysis of Variance; Animals; Catheterization; Cell Count; Central Nervous System Agents; Ferrets; Microelectrodes; Neurons; Photomicrography; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Valine; Vision, Binocular; Vision, Monocular; Visual Cortex; Visual Perception | 2010 |
The lateral paragigantocellular nucleus modulates parasympathetic cardiac neurons: a mechanism for rapid eye movement sleep-dependent changes in heart rate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Heart; Heart Rate; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medulla Oblongata; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Time Factors; Vagus Nerve; Valine | 2010 |
Trace and contextual fear conditioning require neural activity and NMDA receptor-dependent transmission in the medial prefrontal cortex.
Topics: Animals; Conditioning, Classical; Fear; GABA Agonists; Male; Memory; Muscimol; Neuronal Plasticity; Prefrontal Cortex; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2010 |
Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Clocks; Biophysics; Calcium; Dopamine; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamates; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Tyrosine 3-Monooxygenase; Valine; Ventral Tegmental Area | 2010 |
NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats.
Topics: Acoustic Stimulation; Amygdala; Animals; Auditory Perception; Conditioning, Classical; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Memory; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Increased dentate gyrus excitability in neuroligin-2-deficient mice in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Carrier Proteins; Cell Adhesion Molecules, Neuronal; Computer Simulation; Dentate Gyrus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; In Vitro Techniques; Inhibition, Psychological; Membrane Proteins; Mice; Mice, Knockout; Models, Neurological; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Receptors, GABA-A; Sodium Channel Blockers; Statistics, Nonparametric; Tetrodotoxin; Valine; Vesicular Inhibitory Amino Acid Transport Proteins | 2011 |
[Protein synthesis is necessary for induction of amnesia, elicited by disruption of long-term memory reconsolidation].
Topics: Amnesia; Animals; Anisomycin; Cycloheximide; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Helix, Snails; Memory; Protein Biosynthesis; Protein Synthesis Inhibitors; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2010 |
Adrenergic receptor-mediated disinhibition of mitral cells triggers long-term enhancement of synchronized oscillations in the olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Norepinephrine; Olfactory Bulb; Pyridazines; Quinoxalines; Rats; Receptors, Adrenergic; Valine | 2010 |
Long-term potentiation of neuronal excitation in the central nucleus of the rat amygdala revealed by imaging with a voltage-sensitive dye.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Animals, Newborn; Anisomycin; Biophysics; Calcium; Carbazoles; Colforsin; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyrroles; Rats; Rats, Wistar; Time Factors; Valine; Voltage-Sensitive Dye Imaging | 2010 |
The effect of intra-locus coeruleus injection of 17beta-estradiol on inflammatory pain modulation in male rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Formaldehyde; Fulvestrant; Inflammation; Locus Coeruleus; Male; Microinjections; Pain; Rats; Rats, Sprague-Dawley; Valine | 2010 |
Metaplasticity at single glutamatergic synapses.
Topics: Anesthetics, Local; Animals; Biophysics; Dendritic Spines; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Long-Term Potentiation; Models, Biological; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetanus Toxin; Tetrodotoxin; Time Factors; Transfection; Valine | 2010 |
Alteration of GABAergic neurotransmission by pulsed infrared laser stimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzylamines; Bicuculline; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Radiation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Inhibitory Postsynaptic Potentials; Lasers; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Pregnancy; Rats; Synaptic Transmission; Temperature; Valine | 2010 |
Cannabinoids excite circadian clock neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adaptation, Ocular; Analgesics; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Benzoxazines; Biophysics; Cannabinoids; Circadian Rhythm; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Transgenic; Morpholines; Motor Activity; Naphthalenes; Neurons; Patch-Clamp Techniques; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Suprachiasmatic Nucleus; Tetrodotoxin; Valine | 2010 |
An NMDA antagonist inhibits light but not GRP-induced phase shifts when administered after the phase-shifting stimulus.
Topics: Analysis of Variance; Animals; Behavior, Animal; Circadian Rhythm; Cricetinae; Excitatory Amino Acid Antagonists; Gastrin-Releasing Peptide; Gastrointestinal Agents; Light; Male; Microinjections; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus; Time Factors; Valine | 2010 |
GPI-1046 increases presenilin-1 expression and restores NMDA channel activity.
Topics: Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; In Vitro Techniques; Male; Membrane Potentials; Neurons; Oxidopamine; Parkinson Disease; Patch-Clamp Techniques; Presenilin-1; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tyrosine 3-Monooxygenase; Up-Regulation; Valine | 2010 |
CDK5 serves as a major control point in neurotransmitter release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cyclin-Dependent Kinase 5; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Munc18 Proteins; Neurons; Neurotransmitter Agents; Protein Kinase Inhibitors; Purines; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Roscovitine; Sodium Channel Blockers; Synapses; Tetrodotoxin; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2010 |
Multivesicular release differentiates the reliability of synaptic transmission between the visual cortex and the somatosensory cortex.
Topics: Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Mice; Models, Neurological; Neural Pathways; Neurons; Nonlinear Dynamics; Patch-Clamp Techniques; Potassium Channel Blockers; Probability; Somatosensory Cortex; Synapses; Synaptic Transmission; Synaptic Vesicles; Tetraethylammonium; Valine; Visual Cortex | 2010 |
Involvement of the 3'-untranslated region of the brain-derived neurotrophic factor gene in activity-dependent mRNA stabilization.
Topics: 3' Untranslated Regions; Animals; Brain-Derived Neurotrophic Factor; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dactinomycin; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, Immediate-Early; Neurons; Nicardipine; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA Precursors; RNA, Messenger; Transfection; Valine | 2010 |
Kv4.2 block of long-term potentiation is partially dependent on synaptic NMDA receptor remodeling.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Hippocampus; Long-Term Potentiation; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Shal Potassium Channels; Synapses; Tissue Culture Techniques; Valine | 2011 |
Encoding of the cough reflex in anesthetized guinea pigs.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citric Acid; Cough; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Mechanoreceptors; Propionates; Quinoxalines; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Recurrent Laryngeal Nerve; Reflex; Respiratory Mucosa; Sensory Receptor Cells; Solitary Nucleus; Substance P; Trachea; Vagus Nerve; Valine | 2011 |
Non-redundant odor coding by sister mitral cells revealed by light addressable glomeruli in the mouse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Channelrhodopsins; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Light; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Odorants; Olfactory Bulb; Olfactory Marker Protein; Olfactory Pathways; Sensory Receptor Cells; Statistics as Topic; Time; Valine | 2010 |
Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdala.
Topics: Action Potentials; Adaptation, Psychological; Amygdala; Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Conditioning, Psychological; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; GABA Antagonists; Gene Expression Regulation; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphinic Acids; Piperidines; Propanolamines; Pyrazoles; Pyridazines; Quinoxalines; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; Signal Transduction; Time Factors; Valine | 2011 |
Protein kinase Mzeta is essential for the induction and maintenance of dopamine-induced long-term potentiation in apical CA1 dendrites.
Topics: Animals; Benzazepines; Biophysics; CA1 Region, Hippocampal; Dactinomycin; Dendrites; Dopamine; Dopamine Antagonists; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Immunosuppressive Agents; In Vitro Techniques; Long-Term Potentiation; Male; Neurons; Patch-Clamp Techniques; Peptides; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Sirolimus; Time Factors; Valine | 2010 |
Developmental maturation of excitation and inhibition balance in principal neurons across four layers of somatosensory cortex.
Topics: Animals; Cerebral Cortex; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Time Factors; Valine | 2011 |
Synapse- and subtype-specific modulation of synaptic transmission by nicotinic acetylcholine receptors in the ventrobasal thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Animals, Newborn; Bicuculline; Cholinesterase Inhibitors; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Galantamine; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Nicotinic Agonists; Patch-Clamp Techniques; Receptors, Nicotinic; Sodium Channel Blockers; Somatosensory Cortex; Synapses; Synaptic Transmission; Tetrodotoxin; Thalamus; Valine | 2011 |
Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Endocytosis; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Membrane Potentials; Microscopy, Confocal; N-Methylaspartate; Nedd4 Ubiquitin Protein Ligases; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA Interference; Transfection; Ubiquitin-Protein Ligases; Ubiquitination; Valine | 2010 |
Nicotine ameliorates NMDA receptor antagonist-induced deficits in contextual fear conditioning through high-affinity nicotinic acetylcholine receptors in the hippocampus.
Topics: Analysis of Variance; Animals; Association Learning; Conditioning, Classical; Excitatory Amino Acid Antagonists; Fear; Hippocampus; Male; Mice; Nicotine; Nicotinic Agonists; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Valine | 2011 |
Information capacity and transmission are maximized in balanced cortical networks with neuronal avalanches.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cerebral Cortex; Computer Simulation; Dose-Response Relationship, Drug; Entropy; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Likelihood Functions; Macaca mulatta; Male; Microelectrodes; Models, Neurological; Nerve Net; Neurons; Organ Culture Techniques; Picrotoxin; Quinoxalines; Rats; Synaptic Transmission; Valine | 2011 |
NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants.
Topics: Analysis of Variance; Animals; Cells, Cultured; Dendritic Spines; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Humans; In Vitro Techniques; Microscopy, Confocal; Nerve Tissue Proteins; Neurons; Neuropeptides; Post-Synaptic Density; Protein Binding; Protein Isoforms; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Transfection; Two-Hybrid System Techniques; Valine | 2011 |
Selective suppression of plasticity in amygdala inputs from temporal association cortex by the external capsule.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amygdala; Animals; Cerebral Cortex; Channelrhodopsins; Dependovirus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Luminescent Proteins; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Patch-Clamp Techniques; Photic Stimulation; Picrotoxin; Time Factors; Valine | 2011 |
Acquisition of Pavlovian fear conditioning using β-adrenoceptor activation of the dorsal premammillary nucleus as an unconditioned stimulus to mimic live predator-threat exposure.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Atenolol; Butoxamine; Conditioning, Classical; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fear; Isoproterenol; Male; Mammillary Bodies; Microinjections; Neural Pathways; Odorants; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Valine | 2011 |
Evaluating the neural basis of temporal order memory for visual stimuli in the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Behavior, Animal; Brain; Cholinergic Antagonists; Discrimination, Psychological; Excitatory Amino Acid Antagonists; Memory; Photic Stimulation; Rats; Scopolamine; Synaptic Transmission; Time Factors; Valine | 2011 |
Parasagittally aligned, mGluR1-dependent patches are evoked at long latencies by parallel fiber stimulation in the mouse cerebellar cortex in vivo.
Topics: Animals; Benzoates; Calcium; Cerebellar Cortex; Electric Stimulation; Estrenes; Evoked Potentials; Glycine; Long-Term Potentiation; Male; Mice; Mice, Inbred Strains; Models, Animal; Nerve Fibers; Purkinje Cells; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Ryanodine; Valine | 2011 |
A circuit model for saccadic suppression in the superior colliculus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Genetically Modified; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Models, Neurological; Nerve Net; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Reaction Time; Saccades; Sodium Channel Blockers; Superior Colliculi; Tetrodotoxin; Valine; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2011 |
Activity-dependent regulation of surface glucose transporter-3.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Biotinylation; Cerebral Cortex; Cyclic GMP; Disks Large Homolog 4 Protein; Dogs; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Glucose Transporter Type 3; Green Fluorescent Proteins; Hexoses; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Potassium Channel Blockers; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptosomes; Thionucleotides; Time Factors; Transfection; Valine | 2011 |
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis.
Topics: Acid Sensing Ion Channels; Acidosis; Amino Acid Transport System y+; Animals; Biophysics; Brain Injuries; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Antagonists; Glucose; Hippocampus; Hydrogen-Ion Concentration; Hypoxia; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mice, Knockout; Mutation; Nerve Tissue Proteins; Neurons; Oligonucleotides; Patch-Clamp Techniques; Picrotoxin; Putrescine; Sodium Channels; Spermine; Tetrazolium Salts; Time Factors; Transfection; Valine | 2011 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Ovarian hormone deficiency reduces intrinsic excitability and abolishes acute estrogen sensitivity in hippocampal CA1 pyramidal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Analysis of Variance; Animals; Biophysics; Electric Stimulation; Estrogens; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Ovariectomy; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyridazines; Rats; Time Factors; Valine | 2011 |
Amyloid β peptide oligomers directly activate NMDA receptors.
Topics: Amyloid beta-Peptides; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Electrophysiological Phenomena; Female; Humans; Memantine; Neurons; Oocytes; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine; Xenopus laevis | 2011 |
Early, time-dependent disturbances of hippocampal synaptic transmission and plasticity after in utero immune challenge.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; In Vitro Techniques; Long-Term Synaptic Depression; Male; Patch-Clamp Techniques; Polysaccharides; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2011 |
Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Dihydrotestosterone; Enzyme Activation; Estrogens; Female; GABA Antagonists; Glucose; Gonadotropin-Releasing Hormone; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Ovariectomy; Ribonucleotides; Valine | 2011 |
Preconditioning effects of tumor necrosis factor-α and glutamate on calcium dynamics in rat organotypic hippocampal cultures.
Topics: Animals; Animals, Newborn; Calcium; Cell Death; Cell Survival; Drug Administration Schedule; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Imidazoles; Male; Nonlinear Dynamics; Organ Culture Techniques; Propidium; Pyridines; Rats; Rats, Wistar; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Valine | 2011 |
Different effects of α-chloralose on spontaneous and evoked GABA release in rat hippocampal CA1 neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bumetanide; CA1 Region, Hippocampal; Cadmium Chloride; Chloralose; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neurons; Patch-Clamp Techniques; Rats; Sodium Channel Blockers; Sodium Potassium Chloride Symporter Inhibitors; Tetrodotoxin; Valine | 2011 |
D-serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor.
Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cells, Cultured; Cerebellum; Chromatography, High Pressure Liquid; D-Amino-Acid Oxidase; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine Agents; Green Fluorescent Proteins; Long-Term Synaptic Depression; Mice; Mice, Transgenic; Microdialysis; Mutation; Patch-Clamp Techniques; Phosphoglycerate Dehydrogenase; Psychomotor Performance; Purkinje Cells; Receptors, Glutamate; Rotarod Performance Test; Serine; Statistics, Nonparametric; Strychnine; Valine | 2011 |
Glutamatergic pre-ictal discharges emerge at the transition to seizure in human epilepsy.
Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Biophysics; Brain Mapping; Confidence Intervals; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Magnesium; Male; Middle Aged; Nerve Net; Potassium Chloride; Quinoxalines; Valine; Young Adult | 2011 |
Use-dependent AMPA receptor block reveals segregation of spontaneous and evoked glutamatergic neurotransmission.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Lidocaine; Male; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Polyamines; Receptors, AMPA; Tetrodotoxin; Valine | 2011 |
A requirement for nuclear factor-kappaB in developmental and plasticity-associated synaptogenesis.
Topics: Animals; Animals, Newborn; Bacterial Proteins; Bicuculline; Cells, Cultured; Computational Biology; Dendrites; Dendritic Spines; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA-A Receptor Antagonists; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Luminescent Proteins; Male; Membrane Proteins; Mice; Mutation; Nerve Tissue Proteins; Neurogenesis; Neuronal Plasticity; NF-kappa B; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Sodium-Activated; Pyramidal Cells; Synapses; Time Factors; Transfection; Valine; Vesicular Inhibitory Amino Acid Transport Proteins | 2011 |
Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Male; Memory; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Oligopeptides; Organophosphonates; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome; Time Factors; Valine | 2011 |
Excitation-inhibition balance in the CA3 network--neuronal specificity and activity-dependent plasticity.
Topics: Animals; CA3 Region, Hippocampal; Convulsants; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Kindling, Neurologic; Male; Nerve Net; Neuronal Plasticity; Neurons; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Seizures; Synaptic Transmission; Valine | 2011 |
Molecular determinants controlling NMDA receptor synaptic incorporation.
Topics: Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; Macromolecular Substances; Male; Mutation; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Transfection; Valine | 2011 |
Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway.
Topics: Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Astrocytes; Biotinylation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Immunoprecipitation; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; SNARE Proteins; Somatosensory Cortex; src-Family Kinases; Tyrosine; Valine | 2011 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine | 2012 |
Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice.
Topics: 4-Aminopyridine; Age Factors; Animals; Bicuculline; Brain; Convulsants; Electric Stimulation; Electroencephalography; Epilepsy; GABA-A Receptor Antagonists; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Knockout; Receptors, N-Methyl-D-Aspartate; Synapsins; Synaptic Transmission; Valine | 2011 |
Synaptic vesicle retrieval time is a cell-wide rather than individual-synapse property.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adaptor Protein Complex 2; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Cells, Cultured; Electric Stimulation; Endocytosis; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Markov Chains; Models, Neurological; Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Synapses; Synaptic Transmission; Synaptic Vesicles; Tetrodotoxin; Time Factors; Transfection; Valine; Vesicular Glutamate Transport Protein 1 | 2011 |
Protein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension.
Topics: Animals; Benzimidazoles; Blood Pressure; Brain Stem; Casein Kinase II; Dichlororibofuranosylbenzimidazole; Excitatory Postsynaptic Potentials; Ganglionectomy; Heart Rate; Hypertension; In Vitro Techniques; Injections, Intraventricular; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Prefrontal Cortex; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System; Valine | 2011 |
Effect of acute soman exposure on GABA(A) receptors in rat hippocampal slices and cultured hippocampal neurons.
Topics: Animals; Animals, Newborn; Anticonvulsants; Atropine; Cells, Cultured; Cholinesterase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Endocytosis; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Microscopy, Confocal; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Pregnancy; Protein Transport; Rats; Receptors, GABA-A; Soman; Valine | 2011 |
GABAA receptor endocytosis in the basolateral amygdala is critical to the reinstatement of fear memory measured by fear-potentiated startle.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic beta-Agonists; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Biotinylation; Conditioning, Classical; Dynamins; Endocytosis; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Immunoprecipitation; Isoproterenol; Male; Maze Learning; Memory; Patch-Clamp Techniques; Propranolol; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Fusion Proteins; Reward; Synaptic Transmission; tat Gene Products, Human Immunodeficiency Virus; Valine | 2011 |
Visual-induced excitation leads to firing pauses in striatal cholinergic interneurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Bicuculline; Cholinergic Agents; Corpus Striatum; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Functional Laterality; GABA-A Receptor Antagonists; In Vitro Techniques; Interneurons; Light; Male; Models, Biological; Phosphinic Acids; Photic Stimulation; Propanolamines; Pyridazines; Rats; Rats, Long-Evans; Regression Analysis; Statistics, Nonparametric; Thalamus; Valine; Visual Pathways | 2011 |
The importance of having Arc: expression of the immediate-early gene Arc is required for hippocampus-dependent fear conditioning and blocked by NMDA receptor antagonism.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Conditioning, Classical; Cytoskeletal Proteins; Excitatory Amino Acid Antagonists; Fear; Gene Expression Regulation; Hippocampus; Male; Nerve Tissue Proteins; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Valine | 2011 |
Experience-dependent plasticity acts via GluR1 and a novel neuronal nitric oxide synthase-dependent synaptic mechanism in adult cortex.
Topics: Analysis of Variance; Animals; Bicuculline; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Long-Term Potentiation; Magnesium; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Patch-Clamp Techniques; Receptors, AMPA; Synapses; Synaptic Transmission; Valine; Vibrissae | 2011 |
GABA(B) restrains release from singly-evoked GABA terminals.
Topics: Analysis of Variance; Animals; Benzylamines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Phosphinic Acids; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Sodium Channel Blockers; Solitary Nucleus; Synapses; Tetrodotoxin; Valine | 2011 |
Modulation of endocannabinoid-mediated long-lasting disinhibition of striatal output by cholinergic interneurons.
Topics: Animals; Animals, Newborn; Benzazepines; Bicuculline; Biophysics; Cannabinoid Receptor Modulators; Cholinergic Agents; Chromones; Corpus Striatum; Dopamine Antagonists; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Interneurons; Long-Term Potentiation; Models, Neurological; Neural Inhibition; Piperidines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Signal Transduction; Sulpiride; Valine | 2011 |
A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα.
Topics: Analysis of Variance; Animals; ARNTL Transcription Factors; Bicuculline; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Circadian Clocks; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Dendrites; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; GTPase-Activating Proteins; Hippocampus; Humans; Immunoprecipitation; Leupeptins; Mice; Mice, Knockout; Mutation; Neurons; Nuclear Proteins; Nuclear Receptor Subfamily 1, Group D, Member 1; Quinoxalines; Rats; RNA, Messenger; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Transfection; Two-Hybrid System Techniques; Valine | 2011 |
Involvement of peripheral ionotropic glutamate receptors in orofacial thermal hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Face; Flavonoids; Hyperalgesia; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Valine | 2011 |
Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche.
Topics: Action Potentials; Animals; Animals, Newborn; Bacterial Proteins; Biophysical Phenomena; Cell Adhesion Molecules, Neuronal; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Matrix Proteins; GABA Antagonists; Glutamic Acid; Green Fluorescent Proteins; Interneurons; Iontophoresis; Luminescent Proteins; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Neurogenesis; Neuropeptide Y; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Picrotoxin; Pro-Opiomelanocortin; Quinoxalines; Reelin Protein; Serine Endopeptidases; Stem Cell Niche; Synaptic Potentials; Time Factors; Valine | 2011 |
PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics.
Topics: A Kinase Anchor Proteins; Analysis of Variance; Animals; Carnitine; Cyclic AMP-Dependent Protein Kinases; Dendrites; Dynamins; Embryo, Mammalian; Energy Metabolism; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Membrane Potential, Mitochondrial; Membrane Transport Proteins; Microscopy, Confocal; Mitochondria; Mitochondrial Precursor Protein Import Complex Proteins; Mitochondrial Proteins; Mutation; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Valine; Vesicular Transport Proteins | 2011 |
Two free radical pathways mediate chemical hypoxia-induced glutamate release in synaptosomes from the prefrontal cortex.
Topics: Adenosine Triphosphate; Animals; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Free Radicals; Glutamic Acid; Hydrogen Peroxide; Hypoxia; Lipid Peroxidation; Male; Mitochondrial Proton-Translocating ATPases; Oxidants; Prefrontal Cortex; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Cyanide; Synaptosomes; Valine | 2012 |
State-dependent, bidirectional modulation of neural network activity by endocannabinoids.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Brain; Cannabinoid Receptor Modulators; Cells, Cultured; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Piperidines; Potassium Channel Blockers; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sodium Channel Blockers; Tetrodotoxin; Valine | 2011 |
CRP1, a protein localized in filopodia of growth cones, is involved in dendritic growth.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Chelating Agents; Chlorocebus aethiops; CREB-Binding Protein; Cystatins; Dendrites; Egtazic Acid; Embryo, Mammalian; Enzyme Inhibitors; Female; Green Fluorescent Proteins; Growth Cones; Hippocampus; Male; Microscopy, Confocal; Neurites; Neurons; Nifedipine; Potassium Chloride; Pseudopodia; Rats; RNA, Messenger; RNA, Small Interfering; Transfection; Up-Regulation; Valine | 2011 |
Bidirectional plasticity in striatonigral synapses: a switch to balance direct and indirect basal ganglia pathways.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Basal Ganglia; Benzazepines; Benzoxazines; Biophysics; Cannabinoids; Chelating Agents; Corpus Striatum; Dopamine Agonists; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Synaptic Depression; Male; Morpholines; Naphthalenes; Neural Pathways; Piperidines; Pyrazoles; Rats; Substantia Nigra; Synapses; Synaptic Transmission; Time Factors; Valine | 2011 |
Presynaptic inhibition of GABAergic synaptic transmission by adenosine in mouse hypothalamic hypocretin neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Animals, Newborn; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Neural Inhibition; Neuropeptides; Orexins; Patch-Clamp Techniques; Presynaptic Terminals; Purinergic Antagonists; Synaptic Transmission; Theobromine; Theophylline; Valine | 2012 |
Influence of sex and estrous cycle on synaptic responses of the medial vestibular nuclei in rats: role of circulating 17β-estradiol.
Topics: Analysis of Variance; Androgens; Animals; Electric Stimulation; Estradiol; Estrogens; Estrous Cycle; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Long-Term Potentiation; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Sex Characteristics; Synapses; Testosterone; Valine; Vestibular Nuclei | 2012 |
A critical role for GluN2B-containing NMDA receptors in cortical development and function.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Immunosuppressive Agents; Mice; Mice, Knockout; Patch-Clamp Techniques; Piperidines; Receptors, N-Methyl-D-Aspartate; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Small Interfering; Sirolimus; Social Behavior; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2011 |
Dorsal versus ventral hippocampal contributions to trace and contextual conditioning: differential effects of regionally selective NMDA receptor antagonism on acquisition and expression.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Conditioning, Classical; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Freezing Reaction, Cataleptic; Hippocampus; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Valine | 2012 |
Sphingomyelinase selectively reduces M1 muscarinic receptors in rat hippocampal membranes.
Topics: Animals; Arrestins; beta-Arrestins; Bicuculline; Biotinylation; Cell Membrane; Drug Interactions; Excitatory Amino Acid Antagonists; G-Protein-Coupled Receptor Kinase 2; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; Immunoprecipitation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Muscarinic Agonists; Patch-Clamp Techniques; Pilocarpine; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sphingomyelin Phosphodiesterase; Time Factors; Valine | 2012 |
Sex difference in stress-induced enhancement of hippocampal CA1 long-term depression during puberty.
Topics: Adrenalectomy; Androgens; Animals; Animals, Newborn; Aspartic Acid; CA1 Region, Hippocampal; Corticosterone; Dexamethasone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucocorticoids; Glutamic Acid; In Vitro Techniques; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Ovariectomy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sex Characteristics; Statistics, Nonparametric; Stress, Psychological; Synaptosomes; Testosterone; Valine | 2012 |
Regulation of neuronal input transformations by tunable dendritic inhibition.
Topics: Animals; Biophysics; Cerebral Cortex; Channelrhodopsins; Dependovirus; DNA-Binding Proteins; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; In Vitro Techniques; Interneurons; Ligand-Gated Ion Channels; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Mutation; Neural Inhibition; Parvalbumins; Patch-Clamp Techniques; Photic Stimulation; Pyramidal Cells; Pyridazines; Receptors, Glycine; RNA, Small Interfering; Synapses; Synaptic Transmission; Transcription Factors; Transduction, Genetic; Valine | 2012 |
Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Isoproterenol; Long-Term Potentiation; Long-Term Synaptic Depression; Methoxamine; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Photic Stimulation; Propranolol; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Valine; Visual Cortex; Visual Pathways | 2012 |
Gamma oscillations are generated locally in an attention-related midbrain network.
Topics: Animals; Animals, Newborn; Atropine; Attention; Biophysics; Brain Mapping; Chickens; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA Modulators; In Vitro Techniques; Mesencephalon; Muscarinic Antagonists; Pentobarbital; Periodicity; Photic Stimulation; Picrotoxin; Receptors, Cholinergic; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synaptic Potentials; Valine | 2012 |
VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Ammonium Chloride; Analysis of Variance; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cholecystokinin; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Knockdown Techniques; Hippocampus; Humans; Inhibitory Postsynaptic Potentials; Mice; Mice, Knockout; Microscopy, Immunoelectron; Mutation; Neurons; Patch-Clamp Techniques; Protein Binding; Protein Transport; R-SNARE Proteins; Rats; Rats, Sprague-Dawley; RNA Interference; SNARE Proteins; Synapses; Synaptic Transmission; Synaptic Vesicles; Synaptosomal-Associated Protein 25; Syntaxin 1; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2012 |
Endogenous ACh effects on NMDA-induced interictal-like discharges along the septotemporal hippocampal axis of adult rats and their modulation by an early life generalized seizure.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Cholinesterase Inhibitors; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; Muscarinic Antagonists; N-Methylaspartate; Neurons; Pentylenetetrazole; Physostigmine; Rats; Rats, Sprague-Dawley; Seizures; Sex Factors; Valine | 2012 |
Synapsin selectively controls the mobility of resting pool vesicles at hippocampal terminals.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Excitatory Amino Acid Antagonists; Fluorescence Recovery After Photobleaching; Gene Expression Regulation; Hippocampus; Humans; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Neurons; Presynaptic Terminals; Protein Kinase Inhibitors; Protein Transport; Purines; Pyridinium Compounds; Quaternary Ammonium Compounds; Roscovitine; Statistics, Nonparametric; Synapsins; Synaptic Vesicles; Time Factors; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2012 |
Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Antigens, Surface; Brain Injuries; Bumetanide; Caspases; Cell Count; Choline; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Humans; Imaging, Three-Dimensional; In Vitro Techniques; Luminescent Proteins; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; Microscopy, Confocal; Nerve Net; Neurons; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Regression Analysis; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors; Statistics, Nonparametric; Thiazoles; Thioglycolates; Time Factors; Valine | 2012 |
Cholinergic induction of input-specific late-phase LTP via localized Ca2+ release in the visual cortex.
Topics: Animals; Calcium; Carbachol; Cholinergic Neurons; Dendrites; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Heparin; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; Protein Synthesis Inhibitors; Rats; Valine; Visual Cortex | 2012 |
Preservation of the hyperdirect pathway of basal ganglia in a rodent brain slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Basal Ganglia; Computer Simulation; Electric Stimulation; Excitatory Amino Acid Antagonists; Frontal Lobe; In Vitro Techniques; Membrane Potentials; Models, Neurological; Neural Pathways; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Substantia Nigra; Synaptic Transmission; Valine | 2012 |
Roles of hippocampal GABA(A) and muscarinic receptors in consolidation of context memory and context-shock association in contextual fear conditioning: a double dissociation study.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Association Learning; Conditioning, Psychological; Electroshock; Excitatory Amino Acid Antagonists; Fear; GABA-A Receptor Agonists; Hippocampus; Male; Memory; Muscarinic Antagonists; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Scopolamine; Serotonin Receptor Agonists; Valine | 2012 |
Post-acquisition release of glutamate and norepinephrine in the amygdala is involved in taste-aversion memory consolidation.
Topics: Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Animals; Area Under Curve; Avoidance Learning; Conditioning, Classical; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium Chloride; Male; Memory; Microdialysis; Norepinephrine; Propranolol; Rats; Rats, Wistar; Saccharin; Taste; Valine | 2012 |
Intraglomerular inhibition shapes the strength and temporal structure of glomerular output.
Topics: Animals; Dendrites; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Olfactory Bulb; Receptors, N-Methyl-D-Aspartate; Valine | 2012 |
MPTP modulates hippocampal synaptic transmission and activity-dependent synaptic plasticity via dopamine receptors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Biophysics; Dopamine Antagonists; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuronal Plasticity; Neurons; Neurotoxins; Patch-Clamp Techniques; Quinoxalines; Receptors, Dopamine; Sodium Channel Blockers; Sulpiride; Tetrodotoxin; Time Factors; Valine | 2012 |
Presynaptic NMDA receptor-mediated modulation of excitatory neurotransmission in the mouse dorsal motor nucleus of the vagus.
Topics: Animals; Biophysics; Chlorides; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamates; In Vitro Techniques; Male; Medulla Oblongata; Mice; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Vagus Nerve; Valine; Zinc Compounds | 2012 |
Inhibition of NMDA-type glutamate receptors induces arousal from torpor in hibernating arctic ground squirrels (Urocitellus parryii).
Topics: Analysis of Variance; Animals; Arctic Regions; Arousal; Body Temperature; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Hibernation; Injections, Intraventricular; Oxygen Consumption; Receptors, N-Methyl-D-Aspartate; Sciuridae; Serotonin Antagonists; Tropanes; Valine | 2012 |
Phosphodiesterase 4 inhibition impairs cocaine-induced inhibitory synaptic plasticity and conditioned place preference.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cocaine; Conditioning, Operant; CREB-Binding Protein; Cyclic Nucleotide Phosphodiesterases, Type 4; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Microinjections; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrosine 3-Monooxygenase; Valine; Ventral Tegmental Area | 2012 |
Inhibiting PKMζ reveals dorsal lateral and dorsal medial striatum store the different memories needed to support adaptive behavior.
Topics: Adaptation, Psychological; Animals; Conditioning, Operant; Corpus Striatum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Gene Expression Regulation, Enzymologic; Long-Term Potentiation; Male; Memory; Peptides; Protein Kinase C; Rats; Rats, Long-Evans; Receptors, AMPA; Reinforcement, Psychology; RNA, Messenger; Time Factors; Valine | 2012 |
Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine Triphosphate; Animals; Animals, Newborn; Cadmium Chloride; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycolysis; Hippocampus; In Vitro Techniques; Lactic Acid; Models, Biological; NAD; Neurons; Organic Chemicals; Oxidative Phosphorylation; Oxygen; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Statistics, Nonparametric; Synapses; Tetrodotoxin; Valine | 2012 |
Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Antibodies; Disease Models, Animal; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Humans; Hyperalgesia; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Injections, Spinal; Male; Mice; Mice, Transgenic; Motor Activity; Neuralgia; Oligodeoxyribonucleotides, Antisense; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spinal Cord; Spinal Nerves; Tetrodotoxin; Thrombospondins; Up-Regulation; Valine | 2012 |
Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem.
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Brain Stem; Chick Embryo; Cochlea; Coturnix; Electric Stimulation; Embryo, Nonmammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Functional Laterality; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; Humans; In Vitro Techniques; Kv1.3 Potassium Channel; Lentivirus; Male; Membrane Potentials; Microtubule-Associated Proteins; Models, Animal; Neural Pathways; Neurons; Okadaic Acid; Patch-Clamp Techniques; Picrotoxin; Pyrans; Quinoxalines; Selective Serotonin Reuptake Inhibitors; Synapsins; Transgenes; Valine | 2013 |
Experience-dependent switch in sign and mechanisms for plasticity in layer 4 of primary visual cortex.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Critical Period, Psychological; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Neuronal Plasticity; Patch-Clamp Techniques; Pyramidal Cells; Rats; Sensory Deprivation; Synaptic Potentials; Time Factors; Valine; Visual Cortex | 2012 |
Presynaptic GABA(B) receptors decrease neurotransmitter release in vestibular nuclei neurons during vestibular compensation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Chick Embryo; Excitatory Amino Acid Antagonists; GABA Agents; In Vitro Techniques; Lysine; Microscopy, Confocal; Microtubule-Associated Proteins; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, GABA-B; Sodium Channel Blockers; Statistics, Nonparametric; Synaptic Potentials; Synaptotagmin I; Synaptotagmin II; Tetrodotoxin; Time Factors; Valine; Vestibular Diseases; Vestibular Nuclei | 2012 |
Enhanced NMDA receptor-dependent thalamic excitation and network oscillations in stargazer mice.
Topics: Action Potentials; Animals; Biophysical Phenomena; Calcium Channels; Disease Models, Animal; Electric Stimulation; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation; Glutamates; In Vitro Techniques; Indoles; Male; Mice; Mice, Mutant Strains; Nerve Net; Neurons; Patch-Clamp Techniques; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synapses; Thalamic Nuclei; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Optogenetic approaches to characterize the long-range synaptic pathways from the hypothalamus to brain stem autonomic nuclei.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Animals, Newborn; Bacterial Proteins; Biophysics; Brain Stem; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ganglia, Autonomic; Genetic Vectors; Heart; Humans; Hypothalamus; In Vitro Techniques; Luminescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neural Pathways; Neurons; Optogenetics; Oxytocin; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Synapses; Synapsins; Tetrodotoxin; Transduction, Genetic; Valine; Vasopressins | 2012 |
Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Ionophores; Calpain; Cycloheximide; Cysteine Proteinase Inhibitors; Dipeptides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emetine; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Ionomycin; K Cl- Cotransporters; Leupeptins; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyramidal Cells; Rats; Rats, Wistar; Statistics, Nonparametric; Symporters; Valine | 2012 |
Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Amino Acid Motifs; Animals; Animals, Newborn; CA1 Region, Hippocampal; Calcium; Calmodulin; Chelating Agents; Disks Large Homolog 4 Protein; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Luminescent Proteins; Male; MAP Kinase Signaling System; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mutation; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Protein Binding; Protein Conformation; Rats; Receptors, AMPA; Sulfotransferases; Transfection; Valine | 2012 |
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Synuclein; Animals; Biophysics; Biotinylation; Cell Line, Tumor; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Fluid; Hippocampus; Humans; Insulin; L-Lactate Dehydrogenase; Long-Term Potentiation; Male; Neuroblastoma; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine | 2012 |
Visual input modulates audiomotor function via hypothalamic dopaminergic neurons through a cooperative mechanism.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Action Potentials; Animals; Apomorphine; Behavior, Animal; Benzazepines; Biotin; Cell Communication; Dopamine Agonists; Dopamine Antagonists; Dopaminergic Neurons; Escape Reaction; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Flufenamic Acid; Functional Laterality; Glycyrrhetinic Acid; Hypothalamus; In Vitro Techniques; Larva; Light; Locomotion; Microscopy, Confocal; Morpholinos; Patch-Clamp Techniques; Photic Stimulation; Psychoacoustics; Receptors, Dopamine D1; Signal-To-Noise Ratio; Time Factors; Valine; Visual Pathways; Zebrafish | 2012 |
Thrombin facilitates seizures through activation of persistent sodium current.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Convulsants; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Ion Channel Gating; Lidocaine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Thrombin; Valine | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Sleep oscillations in the thalamocortical system induce long-term neuronal plasticity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Cats; Chelating Agents; Egtazic Acid; Electric Stimulation; Electromyography; Electrooculography; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sleep; Somatosensory Cortex; Statistics, Nonparametric; Thalamus; Valine; Wakefulness | 2012 |
Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex.
Topics: Anesthetics, Local; Animals; Bacterial Proteins; Carrier Proteins; Channelrhodopsins; Disease Models, Animal; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; Forelimb; Hyperalgesia; In Vitro Techniques; Ischemia; Luminescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Optogenetics; Physical Stimulation; Quinoxalines; Reperfusion Injury; Tetrodotoxin; Valine | 2012 |
OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Long-Term Potentiation; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Picrotoxin; Plant Lectins; Receptors, Nicotinic; RNA, Messenger; Valine; Voltage-Sensitive Dye Imaging | 2012 |
Diabetes onset influences hippocampal synaptic plasticity in streptozotocin-treated rats.
Topics: Age Factors; Age of Onset; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Diabetes Mellitus, Experimental; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Neural Pathways; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Streptozocin; Synapses; Valine | 2012 |
Regulation of acetylcholinesterase activity by nitric oxide in rat neuromuscular junction via N-methyl-D-aspartate receptor activation.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Glutamic Acid; Male; Miniature Postsynaptic Potentials; Neuromuscular Junction; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraoxon; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Valine | 2013 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
NMDA receptors control cue-outcome selectivity and plasticity of orbitofrontal firing patterns during associative stimulus-reward learning.
Topics: Action Potentials; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Choice Behavior; Conditioning, Operant; Cues; Discriminant Analysis; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Lidocaine; Male; Neuronal Plasticity; Neurons; Odorants; Prefrontal Cortex; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reward; ROC Curve; Spectrum Analysis; Statistics, Nonparametric; Tritium; Valine | 2012 |
Cholinergic receptor activation induces a relative facilitation of synaptic responses in the entorhinal cortex during theta- and gamma-frequency stimulation of parasubicular inputs.
Topics: Acetylcholine; Animals; Anthracenes; Brain Waves; Carbachol; Cholinergic Agents; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Neural Pathways; Phosphinic Acids; Propanolamines; Pyrimidines; Rats; Rats, Long-Evans; Receptors, Cholinergic; Synapses; Valine | 2013 |
Paired stimulation between CA3 and CA1 alters excitability of CA3 in the rat hippocampus.
Topics: Action Potentials; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Channelrhodopsins; Colchicine; In Vitro Techniques; Neurons; Photic Stimulation; Rats; Rats, Transgenic; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Valine | 2013 |
Involvement of NMDA receptors in nicotine-mediated central control of hypotensive effects.
Topics: Animals; Blood Pressure; Bradycardia; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypotension; Male; Nicotine; Nicotinic Agonists; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Solitary Nucleus; Valine | 2012 |
Oxygen-sensitive reduction in Ca²⁺-activated K⁺ channel open probability in turtle cerebrocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biophysics; Calcium; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Hypoxia; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Oxygen; Patch-Clamp Techniques; Phorbol Esters; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Probability; Pyramidal Cells; Sodium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Turtles; Valine | 2013 |
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Axons; Brain; Bromodeoxyuridine; Calcium; Cell Differentiation; Cell Transplantation; Cells, Cultured; Dendrites; Embryonic Stem Cells; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Fetus; Fluorescent Dyes; Gene Expression Profiling; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Humans; In Vitro Techniques; Mice; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Nerve Net; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Patch-Clamp Techniques; Pluripotent Stem Cells; Pregnancy; Pyramidal Cells; RNA, Messenger; Synapses; Synaptic Potentials; Transcription Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Valine; Vesicular Glutamate Transport Protein 1 | 2013 |
Presynaptic muscarinic receptors reduce synaptic depression and facilitate its recovery at hippocampal GABAergic synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; GABAergic Neurons; Hippocampus; Inhibitory Postsynaptic Potentials; Methacholine Chloride; Muscarinic Agonists; Pregnancy; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Valine | 2014 |
Astrocytes release D-serine by a large vesicle.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Calcium; Cytoplasmic Vesicles; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Exocytosis; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Microscopy, Electron, Transmission; Patch-Clamp Techniques; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Serine; Valine | 2013 |
Presynaptic serotonergic gating of the subthalamonigral glutamatergic projection.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analysis of Variance; Animals; Benzopyrans; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABAergic Neurons; Glutamates; In Vitro Techniques; Ion Channel Gating; Male; Mice; Morpholines; Neural Pathways; Patch-Clamp Techniques; Presynaptic Terminals; Pyridines; Pyrroles; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sodium Channel Blockers; Substantia Nigra; Subthalamic Nucleus; Tetrodotoxin; Valine | 2013 |
The balance of striatal feedback transmission is disrupted in a model of parkinsonism.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Biophysics; Calcium; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Feedback, Physiological; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Lidocaine; Lysine; Male; Mice; Mice, Transgenic; Monte Carlo Method; Neostriatum; Neural Inhibition; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission; Time Factors; Valine | 2013 |
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Channelrhodopsins; Corpus Striatum; Corticosterone; Disease Models, Animal; DNA Breaks, Double-Stranded; Excitatory Amino Acid Antagonists; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Histones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Photic Stimulation; Quinoxalines; Reactive Oxygen Species; Stress, Physiological; tau Proteins; Valine | 2013 |
Novel GABAergic circuits mediating excitation/inhibition of Cajal-Retzius cells in the developing hippocampus.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Interneurons; Light; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Mice, Transgenic; Mutation; Nerve Net; Neural Inhibition; Optogenetics; Patch-Clamp Techniques; Proteins; Pyridazines; Quinoxalines; Receptors, CXCR4; RNA, Untranslated; Sodium Channel Blockers; Somatostatin; Synaptic Potentials; Tetrodotoxin; Valine | 2013 |
Axonal translation of β-catenin regulates synaptic vesicle dynamics.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; beta Catenin; Cyclodextrins; Cycloheximide; Diffusion Chambers, Culture; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Microscopy, Confocal; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridinium Compounds; Rats; RNA, Messenger; RNA, Ribosomal; RNA, Small Interfering; Statistics, Nonparametric; Synaptic Vesicles; Time Factors; Tubulin; Valine | 2013 |
Glucocorticoid receptors in the prefrontal cortex regulate dopamine efflux to stress via descending glutamatergic feedback to the ventral tegmental area.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Area Under Curve; Aza Compounds; Chromatography, High Pressure Liquid; Dopamine; Efferent Pathways; Excitatory Amino Acid Antagonists; Glutamic Acid; Heterocyclic Compounds, 4 or More Rings; Hormone Antagonists; Male; Microdialysis; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological; Tail; Valine; Ventral Tegmental Area | 2013 |
Exposure to cocaine regulates inhibitory synaptic transmission in the nucleus accumbens.
Topics: Anesthetics, Local; Animals; Cocaine; Conditioning, Operant; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Self Administration; Synapses; Tetrodotoxin; Time Factors; Valine | 2013 |
Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA.
Topics: Animals; Bacterial Proteins; Channelrhodopsins; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hypothalamus; In Vitro Techniques; Light; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Pathways; Neurotensin; Pyrazoles; Quinolines; Quinoxalines; Receptors, Neurotensin; Reward; Self Stimulation; Signal Transduction; Tyrosine 3-Monooxygenase; Valine; Ventral Tegmental Area | 2013 |
Double dissociation between the anterior cingulate cortex and nucleus accumbens core in encoding the context versus the content of pavlovian cocaine cue extinction.
Topics: Analysis of Variance; Animals; Baclofen; Cocaine; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; GABA-A Receptor Agonists; Gyrus Cinguli; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Valine | 2013 |
Modulation of mGluR-dependent MAP1B translation and AMPA receptor endocytosis by microRNA miR-146a-5p.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Cells, Cultured; Dendrites; Electric Stimulation; Embryo, Mammalian; Endocytosis; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation; Hippocampus; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; MicroRNAs; Microtubule-Associated Proteins; Neurons; Patch-Clamp Techniques; Receptors, AMPA; RNA, Messenger; RNA, Small Interfering; Transfection; Valine | 2013 |
Neural origin of evoked potentials during thalamic deep brain stimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Deep Brain Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; Lidocaine; Male; Muscimol; Neurons; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine | 2013 |
Memory reconsolidation allows the consolidation of a concomitant weak learning through a synaptic tagging and capture mechanism.
Topics: Animals; Behavior, Animal; CA1 Region, Hippocampal; Conditioning, Psychological; Extinction, Psychological; Fear; Learning; Male; Maze Learning; Memory; Memory, Long-Term; Memory, Short-Term; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Valine | 2013 |
Transmission of the respiratory rhythm to trigeminal and hypoglossal motor neurons in the American Bullfrog (Lithobates catesbeiana).
Topics: Action Potentials; Animals; Brain Stem; Choline O-Acetyltransferase; Excitatory Amino Acid Antagonists; Fluoresceins; Hypoglossal Nerve; In Vitro Techniques; Magnesium; Motor Neurons; Physical Stimulation; Quinoxalines; Rana catesbeiana; Respiratory Mechanics; Trigeminal Nerve; Valine | 2013 |
Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake.
Topics: Alcohol Deterrents; Alcohol Drinking; Amygdala; Animals; Avoidance Learning; Bacterial Proteins; Cerebral Cortex; Conditioning, Operant; Drug Resistance; Ethanol; Excitatory Amino Acid Antagonists; Halorhodopsins; Luminescent Proteins; Male; Nerve Tissue Proteins; Nucleus Accumbens; Optogenetics; Patch-Clamp Techniques; Piperidines; Prefrontal Cortex; Quinine; Random Allocation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA Interference; RNA, Small Interfering; Valine | 2013 |
Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking.
Topics: Acetylcholine; Anesthetics, Local; Animals; Benzazepines; Cholinergic Antagonists; Cocaine; Cues; Dopamine; Dopamine Agonists; Drug-Seeking Behavior; Lidocaine; Male; Mecamylamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine; Time Factors; Valine; Ventral Tegmental Area | 2013 |
Potassium channels control the interaction between active dendritic integration compartments in layer 5 cortical pyramidal neurons.
Topics: Alkaloids; Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Signaling; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Indoles; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Potassium Channels; Probability; Pyramidal Cells; Quinolines; Rats; Rats, Wistar; Somatosensory Cortex; Time Factors; Valine | 2013 |
Cholinergic modulation of primary afferent glutamatergic transmission in rat medullary dorsal horn neurons.
Topics: Acetylcholine; Anesthetics, Local; Animals; Animals, Newborn; Cholinergic Agents; Drug Interactions; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Medulla Oblongata; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Synaptic Transmission; Tetrodotoxin; Valine | 2013 |
Long-term depression of inhibitory synaptic transmission induced by spike-timing dependent plasticity requires coactivation of endocannabinoid and muscarinic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; CA1 Region, Hippocampal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cholinergic Agents; Endocannabinoids; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synaptic Transmission; Valine | 2013 |
BLA to vHPC inputs modulate anxiety-related behaviors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Anxiety; Bacterial Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Channelrhodopsins; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; Halorhodopsins; Hippocampus; In Vitro Techniques; Luminescent Proteins; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2013 |
ALX 1393 inhibits spontaneous network activity by inducing glycinergic tonic currents in the spinal ventral horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Anterior Horn Cells; Biophysical Phenomena; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Net; Organ Culture Techniques; Patch-Clamp Techniques; Serine; Spinal Cord; Time Factors; Valine | 2013 |
Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation.
Topics: Acetylcholine; Action Potentials; Animals; Animals, Newborn; Biological Clocks; CA1 Region, Hippocampal; Cholinergic Agents; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; In Vitro Techniques; Male; Mice; Muscarine; Nickel; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Pyramidal Cells; Pyrimidines; Quinoxalines; Sodium Channel Blockers; Sodium Channels; Valine | 2013 |
Sound localization ability and glycinergic innervation of the superior olivary complex persist after genetic deletion of the medial nucleus of the trapezoid body.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Animals; Animals, Newborn; Auditory Pathways; Early Growth Response Protein 2; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Antagonists; Functional Laterality; Glycine; Glycine Plasma Membrane Transport Proteins; Homeodomain Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Olivary Nucleus; Patch-Clamp Techniques; Sound Localization; Strychnine; Valine | 2013 |
Extinguishing trace fear engages the retrosplenial cortex rather than the amygdala.
Topics: Amygdala; Animals; Behavior, Animal; Cerebral Cortex; Conditioning, Psychological; Extinction, Psychological; Extracellular Signal-Regulated MAP Kinases; Fear; Male; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Valine | 2014 |
Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Channelrhodopsins; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Hypothalamic Hormones; Hypothalamus; Melanins; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Neural Pathways; Neurons; Optogenetics; Pituitary Hormones; Sleep, REM; Theta Rhythm; Transduction, Genetic; Valine | 2013 |
Membrane potential correlates of sensory perception in mouse barrel cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; Facial Nerve; Glutamate Decarboxylase; Homeodomain Proteins; Luminescent Proteins; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Parvalbumins; Physical Stimulation; Sensory Receptor Cells; Signal Detection, Psychological; Somatosensory Cortex; Tetrodotoxin; Transcription Factors; Valine; Vibrissae | 2013 |
Matrix metalloprotease activity shapes the magnitude of EPSPs and spike plasticity within the hippocampal CA3 network.
Topics: Action Potentials; Analysis of Variance; Animals; Biophysics; CA3 Region, Hippocampal; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Matrix Metalloproteinases; Neuronal Plasticity; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Synapses; Valine | 2014 |
Light adaptation increases response latency of alpha ganglion cells via a threshold-like nonlinearity.
Topics: Adaptation, Ocular; Animals; Animals, Newborn; Biophysical Phenomena; Computer Simulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Models, Neurological; Nonlinear Dynamics; Patch-Clamp Techniques; Photic Stimulation; Reaction Time; Retina; Retinal Ganglion Cells; Valine | 2014 |
Over-expression of Mash1 improves the GABAergic differentiation of bone marrow mesenchymal stem cells in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Count; Cell Differentiation; Cells, Cultured; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; GABAergic Neurons; Glutamate Decarboxylase; Male; Membrane Potentials; Mesenchymal Stem Cells; Neurons; Phosphopyruvate Hydratase; Picrotoxin; Rats; Rats, Sprague-Dawley; Sesterterpenes; Valine | 2013 |
Memory expression is independent of memory labilization/reconsolidation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Association Learning; Brachyura; Escape Reaction; Excitatory Amino Acid Antagonists; Freezing Reaction, Cataleptic; Memory; Mental Recall; Retention, Psychology; Valine | 2013 |
Copper chelation and exogenous copper affect circadian clock phase resetting in the suprachiasmatic nucleus in vitro.
Topics: Animals; Carbazoles; Chelating Agents; Circadian Clocks; Copper; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Indole Alkaloids; Male; Mice; Mice, Inbred C57BL; Molybdenum; Phenanthrolines; Quinoxalines; Suprachiasmatic Nucleus; Valine | 2014 |
Distal connectivity causes summation and division across mouse visual cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Channelrhodopsins; Electric Stimulation; Electroporation; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Neurons; Optogenetics; Photic Stimulation; Pregnancy; Red Fluorescent Protein; Statistics, Nonparametric; Valine; Visual Cortex; Visual Pathways; Visual Perception | 2014 |
Mu-opioid stimulation in rat prefrontal cortex engages hypothalamic orexin/hypocretin-containing neurons, and reveals dissociable roles of nucleus accumbens and hypothalamus in cortically driven feeding.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Feeding Behavior; Hypothalamus; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Neural Pathways; Neurons; Neuropeptides; Nucleus Accumbens; Oncogene Proteins v-fos; Orexins; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Statistics, Nonparametric; Valine | 2013 |
Remote optogenetic activation and sensitization of pain pathways in freely moving mice.
Topics: Afferent Pathways; Animals; Avoidance Learning; Cells, Cultured; Channelrhodopsins; Female; Ganglia, Spinal; Green Fluorescent Proteins; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; NAV1.8 Voltage-Gated Sodium Channel; Optogenetics; Pain; Pain Threshold; Receptors, Purinergic P2X3; Sensory Receptor Cells; tau Proteins; Valine; Wakefulness | 2013 |
Acute stress causes rapid synaptic insertion of Ca2+ -permeable AMPA receptors to facilitate long-term potentiation in the hippocampus.
Topics: Animals; Biotinylation; Calcium; Dexamethasone; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glucocorticoids; Hippocampus; Hormone Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; Mifepristone; Muscarinic Antagonists; Patch-Clamp Techniques; Phosphorylation; Rats; Rats, Wistar; Receptors, AMPA; Restraint, Physical; Valine | 2013 |
Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.
Topics: Animals; Animals, Newborn; Cerebellum; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Humans; In Vitro Techniques; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neurons; Psychomotor Performance; Quinoxalines; Reaction Time; Recognition, Psychology; Sodium Channel Blockers; Tetrodotoxin; Valine | 2014 |
Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3.
Topics: Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Complement C3; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Net; Neurons; Picrotoxin; Synapses; Ultrasonography; Valine | 2014 |
Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; HEK293 Cells; Humans; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mutation; Neurons; Presynaptic Terminals; Receptors, Glycine; Sodium Channel Blockers; Spinal Cord; Stiff-Person Syndrome; Tetrodotoxin; Valine | 2014 |
Differential conduction velocity regulation in ipsilateral and contralateral collaterals innervating brainstem coincidence detector neurons.
Topics: Animals; Axons; Brain Stem; Chick Embryo; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Functional Laterality; GABA Antagonists; Imaging, Three-Dimensional; In Vitro Techniques; Male; Models, Neurological; Neural Conduction; Neural Pathways; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Valine | 2014 |
Optogenetic assessment of horizontal interactions in primary visual cortex.
Topics: Action Potentials; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Excitatory Amino Acid Antagonists; Female; Luminescent Proteins; Male; Microscopy, Confocal; Neurons; Optogenetics; Orientation; Photic Stimulation; Quinoxalines; Rhodopsin; Synapsins; Tupaiidae; Valine; Visual Cortex; Visual Pathways | 2014 |
A specific role for hippocampal mossy fiber's zinc in rapid storage of emotional memories.
Topics: Analysis of Variance; Animals; Chelating Agents; Conditioning, Classical; Ditiocarb; Edetic Acid; Emotions; Excitatory Amino Acid Antagonists; Freezing Reaction, Cataleptic; Hippocampus; Male; Memory; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Time Factors; Valine; Zinc | 2014 |
PSD-93 deletion inhibits Fyn-mediated phosphorylation of NR2B and protects against focal cerebral ischemia.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Guanylate Kinases; Hippocampus; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nervous System Diseases; Proto-Oncogene Proteins c-fyn; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2014 |
Control over a stressor involves the posterior dorsal striatum and the act/outcome circuit.
Topics: Animals; Anxiety; Corpus Striatum; Escape Reaction; Learning; Male; Oncogene Proteins v-fos; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Stress, Psychological; Valine | 2014 |
Inhibition of food intake by PACAP in the hypothalamic ventromedial nuclei is mediated by NMDA receptors.
Topics: Animals; Arabidopsis Proteins; Eating; Excitatory Amino Acid Antagonists; Feeding Behavior; Male; Neurotransmitter Agents; Nuclear Proteins; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Tyrosine; Valine; Ventromedial Hypothalamic Nucleus | 2014 |
Electrophysiological characterization of methyleugenol: a novel agonist of GABA(A) receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Eugenol; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; GABA Agents; GABA-A Receptor Agonists; Glutamic Acid; Glycine; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Valine | 2014 |
A hybrid electrical/chemical circuit in the spinal cord generates a transient embryonic motor behavior.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Genetically Modified; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Nonmammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Green Fluorescent Proteins; Motor Activity; Motor Neurons; Nerve Net; Neural Pathways; Rhombencephalon; Spinal Cord; Synapses; Transcription Factors; Valine; Zebrafish; Zebrafish Proteins | 2014 |
Long-term potentiation in hilar circuitry modulates gating by the dentate gyrus.
Topics: Analysis of Variance; Animals; Biophysics; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; Nerve Net; Neurons; Pyridazines; Rats; Rats, Sprague-Dawley; Valine; Voltage-Sensitive Dye Imaging | 2014 |
Long-term temporal imprecision of information coding in the anterior cingulate cortex of mice with peripheral inflammation or nerve injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cognition; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Freund's Adjuvant; Gyrus Cinguli; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Valine | 2014 |
Spinal NMDA receptor activation constrains inactivity-induced phrenic motor facilitation in Charles River Sprague-Dawley rats.
Topics: Animals; Excitatory Amino Acid Antagonists; Male; Motor Neurons; Neuronal Plasticity; Phrenic Nerve; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tumor Necrosis Factor-alpha; Valine | 2014 |
Contribution of Ih to the relative facilitation of synaptic responses induced by carbachol in the entorhinal cortex during repetitive stimulation of the parasubiculum.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Neural Pathways; Potassium Channels; Pyrimidines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Valine | 2014 |
Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia.
Topics: Animals; Animals, Newborn; Carrier Proteins; Corpus Striatum; Cricetinae; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Dystonin; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Magnesium; Male; Mutation; Nerve Tissue Proteins; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Time Factors; Valine | 2014 |
Alpha and gamma oscillations characterize feedback and feedforward processing in monkey visual cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Feedback, Physiological; Macaca; Neurons; Photic Stimulation; Psychomotor Performance; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Valine; Visual Cortex | 2014 |
A mechanistic study on urine retention in d-amphetamine addicts.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine | 2014 |
Sex Differences Distinguish Intracortical Glutamate Receptor-Mediated Regulation of Extracellular Dopamine Levels in the Prefrontal Cortex of Adult Rats.
Topics: Analysis of Variance; Animals; Benzylamines; Bicuculline; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Estrous Cycle; Excitatory Amino Acid Agents; Extracellular Fluid; Female; GABA Agents; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Phosphinic Acids; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sex Differentiation; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2016 |
N-methyl-D-aspartate receptor agonism and antagonism within the amygdaloid central nucleus suppresses pain affect: differential contribution of the ventrolateral periaqueductal gray.
Topics: Animals; Central Amygdaloid Nucleus; Dose-Response Relationship, Drug; Electroshock; Male; N-Methylaspartate; Narcotic Antagonists; Pain; Pain Perception; Peptide Fragments; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Random Allocation; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reflex; Somatostatin; Valine; Vocalization, Animal | 2014 |
Distinct representation and distribution of visual information by specific cell types in mouse superficial superior colliculus.
Topics: Action Potentials; Animals; Channelrhodopsins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamate Decarboxylase; Green Fluorescent Proteins; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neurons; Pyridazines; Quinoxalines; Receptors, Neurotensin; Superior Colliculi; Valine; Vesicular Inhibitory Amino Acid Transport Proteins; Visual Fields; Visual Pathways | 2014 |
Pro-brain-derived neurotrophic factor inhibits GABAergic neurotransmission by activating endocytosis and repression of GABAA receptors.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Inhibitory Postsynaptic Potentials; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2014 |
Frequency-specific response facilitation of supra and infragranular barrel cortical neurons depends on NMDA receptor activation in rats.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Muscarinic Antagonists; Neuronal Plasticity; Neurons; Physical Stimulation; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Valine; Vibrissae | 2014 |
Differential role of insular cortex muscarinic and NMDA receptors in one-trial appetitive taste learning.
Topics: Animals; Avoidance Learning; Cerebral Cortex; Excitatory Amino Acid Antagonists; Male; Muscarinic Antagonists; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Saccharin; Scopolamine; Taste; Valine | 2014 |
Quinolinic acid induces disrupts cytoskeletal homeostasis in striatal neurons. Protective role of astrocyte-neuron interaction.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Communication; Cell Survival; Cells, Cultured; Chelating Agents; Coculture Techniques; Corpus Striatum; Culture Media, Conditioned; Cytoskeleton; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Homeostasis; Neurons; Phosphorylation; Pregnancy; Quinolinic Acid; Rats; Rats, Wistar; Valine | 2015 |
Sensory gating of an embryonic zebrafish interneuron during spontaneous motor behaviors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Afferent Pathways; Animals; Embryo, Nonmammalian; Excitatory Amino Acid Antagonists; Glycine Agents; Inhibitory Postsynaptic Potentials; Interneurons; Larva; Nerve Net; Patch-Clamp Techniques; Physical Stimulation; Sensory Gating; Sodium Channel Blockers; Spinal Cord; Strychnine; Swimming; Tetrodotoxin; Valine; Zebrafish | 2014 |
Regulation of neuronal gene expression and survival by basal NMDA receptor activity: a role for histone deacetylase 4.
Topics: Animals; Cell Survival; Cells, Cultured; Female; Gene Expression Regulation; Gene Knockdown Techniques; Hippocampus; Histone Deacetylases; Male; Mice; Nerve Degeneration; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine | 2014 |
Essential role of presynaptic NMDA receptors in activity-dependent BDNF secretion and corticostriatal LTP.
Topics: Animals; Antibodies; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Long-Term Potentiation; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Models, Biological; Neurons; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Valine | 2014 |
Traumatic brain injury induces rapid enhancement of cortical excitability in juvenile rats.
Topics: Animals; Animals, Newborn; Biophysics; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine | 2015 |
Participation of NMDA receptors in the lateral hypothalamus in gastric erosion induced by cold-water restraint.
Topics: Analysis of Variance; Animals; Cold Temperature; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stomach Ulcer; Valine | 2015 |
Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η.
Topics: 14-3-3 Proteins; Animals; Animals, Newborn; Antidepressive Agents; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Antagonists; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Immunoprecipitation; Male; Mice; Neurons; Phenols; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; RNA, Messenger; Stress, Psychological; Swimming; Synaptosomes; Transduction, Genetic; Valine | 2015 |
Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Dexamethasone; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucocorticoids; Hippocampus; Hormone Antagonists; Humans; Memory Disorders; Memory, Episodic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mutation; Neuronal Plasticity; Quinoxalines; Receptors, Glucocorticoid; Recognition, Psychology; Valine | 2015 |
Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Valine; Ventral Tegmental Area | 2015 |
Tumor necrosis factor-α potentiates long-term potentiation in the rat dentate gyrus after acute hypoxia.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Dentate Gyrus; Electric Stimulation; Excitatory Postsynaptic Potentials; Hypoxia; Imidazoles; In Vitro Techniques; Interleukin-1beta; L-Lactate Dehydrogenase; Lipopolysaccharides; Long-Term Potentiation; Male; Patch-Clamp Techniques; Pyridines; Rats; Tumor Necrosis Factor-alpha; Valine | 2015 |
Cell-specific activity-dependent fractionation of layer 2/3→5B excitatory signaling in mouse auditory cortex.
Topics: Animals; Animals, Newborn; Auditory Cortex; Auditory Pathways; Excitatory Amino Acid Antagonists; Female; Flavoproteins; GABA Antagonists; In Vitro Techniques; Inferior Colliculi; Male; Mice; Mice, Inbred ICR; Models, Neurological; Nerve Net; Neurons; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Synaptic Potentials; Valine | 2015 |
Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.
Topics: Animals; Bicuculline; Cells, Cultured; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Knockout; Neurons; Promoter Regions, Genetic; Protein Subunits; Rats; Receptors, GABA-A; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2015 |
Enhanced corticosteroid signaling alters synaptic plasticity in the dentate gyrus in mice lacking the fragile X mental retardation protein.
Topics: Adrenal Cortex Hormones; Animals; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; Hormone Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Neuronal Plasticity; Patch-Clamp Techniques; Restraint, Physical; Signal Transduction; Stress, Psychological; Time Factors; Valine | 2015 |
Ethanol withdrawal is required to produce persisting N-methyl-D-aspartate receptor-dependent hippocampal cytotoxicity during chronic intermittent ethanol exposure.
Topics: Animals; Antigens, Nuclear; Central Nervous System Depressants; Ethanol; Hippocampus; Immunohistochemistry; In Vitro Techniques; Nerve Tissue Proteins; Nissl Bodies; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Valine | 2015 |
Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus.
Topics: Adenosine Triphosphate; Animals; CA1 Region, Hippocampal; Dioxolanes; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Guinea Pigs; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Microtomy; N-Methylaspartate; Neurons; Purines; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Tissue Culture Techniques; Valine | 2015 |
Seizure-related regulation of GABAA receptors in spontaneously epileptic rats.
Topics: Animals; Biotinylation; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Agonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Muscarinic Agonists; Neurons; Pilocarpine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Valine | 2015 |
Induction of long-term potentiation and long-term depression is cell-type specific in the spinal cord.
Topics: Animals; Biophysics; Calcium; Carbocyanines; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Long-Term Potentiation; Long-Term Synaptic Depression; Mice; Mice, Transgenic; Nerve Net; Neurons; Patch-Clamp Techniques; Spinal Cord; Valine | 2015 |
Synaptic strength at the temporoammonic input to the hippocampal CA1 region in vivo is regulated by NMDA receptors, metabotropic glutamate receptors and voltage-gated calcium channels.
Topics: Animals; CA1 Region, Hippocampal; Calcium Channels, L-Type; Cyclopropanes; Dentate Gyrus; Dose-Response Relationship, Drug; Electric Stimulation; Electrocorticography; Electrodes, Implanted; Excitatory Postsynaptic Potentials; Gallopamil; Glycine; Long-Term Potentiation; Male; Neurotransmitter Agents; Perforant Pathway; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Valine | 2015 |
D-Serine and D-Cycloserine Reduce Compulsive Alcohol Intake in Rats.
Topics: Alcohol Drinking; Animals; Compulsive Behavior; Cycloserine; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Prefrontal Cortex; Rats; Rats, Wistar; Saccharin; Serine; Valine | 2015 |
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels regulate firing of globus pallidus neurons in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Animals; Cardiotonic Agents; Cesium; Chlorides; Excitatory Amino Acid Antagonists; Globus Pallidus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Mice; Mice, Inbred C57BL; Neurons; Posture; Pyrimidines; Rats; Rats, Wistar; Subthalamic Nucleus; Valine; Wakefulness | 2015 |
Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Action Potentials; Animals; Dendrites; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; GABAergic Neurons; Glutamate Decarboxylase; Hippocampus; Male; Maze Learning; Mice; Mice, Transgenic; Parvalbumins; Phenotype; Reflex, Startle; Schizophrenia; Somatostatin; Valine | 2015 |
A corticothalamic switch: controlling the thalamus with dynamic synapses.
Topics: Animals; Bacterial Proteins; Central Nervous System Stimulants; Channelrhodopsins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Luminescent Proteins; Mice; Mice, Inbred ICR; Mice, Transgenic; N-Methylaspartate; Neural Pathways; Optogenetics; Picrotoxin; Receptors, Neurotensin; Somatosensory Cortex; Synapses; Thalamus; Valine | 2015 |
Potentiation of tonic GABAergic inhibition by activation of postsynaptic kainate receptors.
Topics: Action Potentials; Animals; Animals, Newborn; Benzodiazepines; Biophysics; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; Hippocampus; Humans; In Vitro Techniques; Kainic Acid; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2015 |
GABAergic inhibition shapes SAM responses in rat auditory thalamus.
Topics: Acoustic Stimulation; Animals; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Male; Neural Inhibition; Neurons; Pyridazines; Rats; Receptors, N-Methyl-D-Aspartate; Sound; Synaptic Transmission; Valine | 2015 |
Early adenosine release contributes to hypoxia-induced disruption of stimulus-induced sharp wave-ripple complexes in rat hippocampal area CA3.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bicuculline; CA3 Region, Hippocampal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA-A Receptor Antagonists; Hypoxia; In Vitro Techniques; Nerve Net; Oxygen; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Valine; Xanthines | 2015 |
μ-Opioid Receptor-Mediated Inhibition of Intercalated Neurons and Effect on Synaptic Transmission to the Central Amygdala.
Topics: Analgesics, Opioid; Animals; Central Amygdaloid Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Narcotic Antagonists; Neural Inhibition; Neurons; Peptides; Quinoxalines; Receptors, Opioid, mu; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2015 |
Activity-dependent plasticity of mouse hippocampal assemblies in vitro.
Topics: Action Potentials; Animals; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nerve Net; Neuronal Plasticity; Neurons; Principal Component Analysis; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2015 |
Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Dendritic Spines; Dizocilpine Maleate; Egtazic Acid; Glutamic Acid; GTP-Binding Proteins; Hippocampus; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Valine | 2015 |
Distinct effects of ventral tegmental area NMDA and acetylcholine receptor blockade on conditioned reinforcement produced by food-associated cues.
Topics: Animals; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reinforcement, Psychology; Scopolamine; Valine; Ventral Tegmental Area | 2015 |
Persistent Adaptations in Afferents to Ventral Tegmental Dopamine Neurons after Opiate Withdrawal.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Afferent Pathways; Animals; Channelrhodopsins; Disease Models, Animal; Dopaminergic Neurons; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; GABAergic Neurons; Glutamate Decarboxylase; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Time Factors; Valine; Ventral Tegmental Area | 2015 |
Canalization of genetic and pharmacological perturbations in developing primary neuronal activity patterns.
Topics: Action Potentials; Animals; Cells, Cultured; Guanylate Kinases; Hippocampus; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Valine | 2016 |
Heparin/heparan sulfates bind to and modulate neuronal L-type (Cav1.2) voltage-dependent Ca(2+) channels.
Topics: Action Potentials; Animals; Binding Sites; Biophysical Phenomena; Calcium Channel Blockers; Calcium Channels, L-Type; CHO Cells; Cricetulus; Diltiazem; Excitatory Amino Acid Antagonists; HEK293 Cells; Heparin; Heparin Lyase; Heparitin Sulfate; Hippocampus; Humans; Microsomes; Models, Molecular; Nerve Net; Neurons; Protein Binding; Time Factors; Valine | 2015 |
Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates Pro-Opiomelanocortin Neurons in the Arcuate Nucleus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Agouti-Related Protein; Animals; Apolipoprotein A-V; Arcuate Nucleus of Hypothalamus; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agents; Gene Expression Regulation; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Neuropeptide Y; Pro-Opiomelanocortin; Sodium Channel Blockers; Tetrodotoxin; Valine | 2016 |
Early network activity propagates bidirectionally between hippocampus and cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Calcium; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; Glutamate Decarboxylase; Hippocampus; In Vitro Techniques; Mice; Nerve Net; Neural Pathways; Picrotoxin; Potassium; Valine | 2016 |
Early postnatal nicotine exposure disrupts the α2* nicotinic acetylcholine receptor-mediated control of oriens-lacunosum moleculare cells during adolescence in rats.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Gene Expression Regulation, Developmental; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine | 2016 |
Exendin-4 antagonizes Aβ1-42-induced suppression of long-term potentiation by regulating intracellular calcium homeostasis in rat hippocampal neurons.
Topics: Amyloid beta-Peptides; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; Exenatide; Hippocampus; Homeostasis; Hypoglycemic Agents; Long-Term Potentiation; Microscopy, Confocal; Neurons; Nifedipine; Patch-Clamp Techniques; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Time Factors; Valine; Venoms | 2015 |
Dendritic Organization of Olfactory Inputs to Medial Amygdala Neurons.
Topics: Action Potentials; Afferent Pathways; Animals; Calcium; Central Nervous System Stimulants; Corticomedial Nuclear Complex; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Transgenic; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Sodium Channel Blockers; Tetrodotoxin; Valine | 2015 |
Hunger States Control the Directions of Synaptic Plasticity via Switching Cell Type-Specific Subunits of NMDA Receptors.
Topics: Agouti-Related Protein; AIDS-Related Complex; Animals; Arcuate Nucleus of Hypothalamus; Diazonium Compounds; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hunger; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Net; Neuronal Plasticity; Neurons; Neuropeptide Y; Pro-Opiomelanocortin; Pyridines; Receptors, N-Methyl-D-Aspartate; Transcriptome; Valine; Zinc | 2015 |
The mesencephalic locomotor region sends a bilateral glutamatergic drive to hindbrain reticulospinal neurons in a tetrapod.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Stem; Calcium; Cell Count; Choline O-Acetyltransferase; Dextrans; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Functional Laterality; Glutamic Acid; In Vitro Techniques; Locomotion; Male; Neurons, Afferent; Urodela; Valine | 2016 |
Dorsal medial prefrontal cortex contributes to conditioned taste aversion memory consolidation and retrieval.
Topics: Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Conditioning, Psychological; Emetine; GABA-A Receptor Agonists; Male; Memory Consolidation; Mental Recall; Muscimol; Prefrontal Cortex; Protein Synthesis Inhibitors; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sulfonamides; Taste Perception; Valine | 2015 |
NMDAR-dependent proteasome activity in the gustatory cortex is necessary for conditioned taste aversion.
Topics: Acetylcysteine; Animals; Avoidance Learning; Conditioning, Psychological; Cysteine Proteinase Inhibitors; Excitatory Amino Acid Antagonists; Male; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Taste; Taste Perception; Valine | 2016 |
The transcription factor calcium-response factor limits NMDA receptor-dependent transcription in the developing brain.
Topics: Animals; Animals, Newborn; Brain; Brain-Derived Neurotrophic Factor; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Tetrodotoxin; Transcription Factors; Valine; Visual Cortex | 2016 |
Correlated Synaptic Inputs Drive Dendritic Calcium Amplification and Cooperative Plasticity during Clustered Synapse Development.
Topics: Age Factors; Animals; Animals, Newborn; Calcium; Calcium Signaling; Dendrites; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Indoles; Membrane Potentials; Neuronal Plasticity; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Valine | 2016 |
NMDA receptors amplify mossy fiber synaptic inputs at frequencies up to at least 750 Hz in cerebellar granule cells.
Topics: Animals; Excitatory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Nerve Fibers; Receptors, N-Methyl-D-Aspartate; Valine | 2016 |
Interdependent Conductances Drive Infraslow Intrinsic Rhythmogenesis in a Subset of Accessory Olfactory Bulb Projection Neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cardiovascular Agents; Excitatory Amino Acid Antagonists; Group II Phospholipases A2; In Vitro Techniques; Mice; Mice, Inbred C57BL; Models, Neurological; Neurons; Olfactory Bulb; Olfactory Pathways; omega-Agatoxin IVA; Periodicity; Pyrimidines; Spider Venoms; Valine | 2016 |
Involvement of hippocampal NMDA receptors in retrieval of spontaneous object recognition memory in rats.
Topics: Analysis of Variance; Animals; Discrimination Learning; Excitatory Amino Acid Agents; Hippocampus; Male; Mental Recall; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Time Factors; Valine | 2016 |
Hippocampus NMDA receptors selectively mediate latent extinction of place learning.
Topics: Analysis of Variance; Animals; Catheters, Indwelling; Excitatory Amino Acid Antagonists; Extinction, Psychological; Hippocampus; Male; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Spatial Learning; Spatial Memory; Valine | 2016 |
Synchronized gamma-frequency inhibition in neocortex depends on excitatory-inhibitory interactions but not electrical synapses.
Topics: Action Potentials; Animals; Bacterial Proteins; Channelrhodopsins; Connexins; Excitatory Amino Acid Antagonists; Gamma Rhythm; Gap Junction delta-2 Protein; Interneurons; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Neocortex; Neural Inhibition; Parvalbumins; Pyramidal Cells; Quinoxalines; Somatostatin; Synapses; Synaptic Transmission; Valine | 2016 |
Heterosynaptic modulation of evoked synaptic potentials in layer II of the entorhinal cortex by activation of the parasubiculum.
Topics: Afferent Pathways; Analysis of Variance; Animals; Bicuculline; Cardiovascular Agents; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Hippocampus; Male; Patch-Clamp Techniques; Phosphinic Acids; Pyrimidines; Rats; Rats, Long-Evans; Synapses; Time Factors; Valine | 2016 |
Synapsin Isoforms Regulating GABA Release from Hippocampal Interneurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; HEK293 Cells; Hippocampus; Humans; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Luminescent Proteins; Mice; Mice, Knockout; Presynaptic Terminals; Protein Isoforms; Synapsins; Valine; Vesicular Inhibitory Amino Acid Transport Proteins | 2016 |
Developmental exposure to PCBs alters the activation of the auditory cortex in response to GABA
Topics: Afferent Pathways; Animals; Animals, Newborn; Auditory Cortex; Electric Stimulation; Environmental Pollutants; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Male; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Pyridazines; Rats; Rats, Long-Evans; Valine | 2016 |
Acquisition and expression of fear memories are distinctly modulated along the dorsolateral periaqueductal gray axis of rats exposed to predator odor.
Topics: Animals; Conditioning, Classical; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fear; Male; Memory; Microinjections; Odorants; Periaqueductal Gray; Rats; Rats, Wistar; Valine | 2016 |
Monosodium glutamate alters the response properties of rat trigeminovascular neurons through activation of peripheral NMDA receptors.
Topics: Action Potentials; Animals; Dura Mater; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Female; Male; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sensory Receptor Cells; Sensory Thresholds; Sex Characteristics; Sodium Glutamate; Tegmentum Mesencephali; Touch; Valine; Vasodilation; Vasodilator Agents | 2016 |
Posterior insular cortex is necessary for conditioned inhibition of fear.
Topics: Animals; Cerebral Cortex; Conditioning, Classical; Fear; GABA-A Receptor Agonists; Inhibition, Psychological; Male; Mental Recall; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2016 |
Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Embryo, Mammalian; Endocytosis; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Female; HEK293 Cells; Hippocampus; Humans; Male; Nerve Tissue Proteins; Neurons; rab GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; RNA, Small Cytoplasmic; Signal Transduction; Synaptic Vesicles; Valine | 2016 |
Effects of memantine on the excitation-inhibition balance in prefrontal cortex.
Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Glutamate Decarboxylase; Green Fluorescent Proteins; Inhibitory Postsynaptic Potentials; Male; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Parvalbumins; Patch-Clamp Techniques; Prefrontal Cortex; Pyridazines; Valine | 2016 |
mGluR5 Exerts Cell-Autonomous Influences on the Functional and Anatomical Development of Layer IV Cortical Neurons in the Mouse Primary Somatosensory Cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors; Dendritic Spines; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Green Fluorescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Peptide Elongation Factor 1; Receptor, Metabotropic Glutamate 5; Somatosensory Cortex; Valine; Vesicular Glutamate Transport Protein 2; Vibrissae | 2016 |
Induction of hippocampal long-term potentiation increases the morphological dynamics of microglial processes and prolongs their contacts with dendritic spines.
Topics: Animals; Cell Communication; Dendritic Spines; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Gene Expression; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Knockout; Microglia; Microtomy; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time-Lapse Imaging; Tissue Culture Techniques; Valine | 2016 |
Dynamic balance of excitation and inhibition rapidly modulates spike probability and precision in feed-forward hippocampal circuits.
Topics: Action Potentials; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Fragile X Mental Retardation Protein; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Quinoxalines; Synaptic Transmission; Valine | 2016 |
Streptozotocin inhibits synaptic transmission and edaravone attenuates streptozotocin-induced electrophysiological changes in CA1 pyramidal neurons of rat hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Antibiotics, Antineoplastic; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Male; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Streptozocin; Synaptic Transmission; Time Factors; Valine | 2016 |
Impaired bidirectional NMDA receptor dependent synaptic plasticity in the dentate gyrus of adult female Fmr1 heterozygous knockout mice.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Estrous Cycle; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Genotype; Glycine; Hindlimb Suspension; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Spatial Behavior; Swimming; Valine | 2016 |
Inward rectifier K
Topics: Action Potentials; Adrenergic beta-1 Receptor Agonists; Animals; Animals, Newborn; Dobutamine; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Potassium Channels, Inwardly Rectifying; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2017 |
Memory trace reactivation and behavioral response during retrieval are differentially modulated by amygdalar glutamate receptors activity: interaction between amygdala and insular cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Analysis of Variance; Animals; Avoidance Learning; Cerebral Cortex; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mental Recall; Neural Pathways; Norepinephrine; Rats; Rats, Wistar; Receptors, Glutamate; Taste; Valine | 2017 |
Respective role of the dorsal hippocampus and the entorhinal cortex during the recombination of previously learned olfactory-tactile associations in the rat.
Topics: Anesthetics, Local; Animals; Association Learning; Cholinergic Antagonists; Discrimination Learning; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Hippocampus; Lidocaine; Male; Neural Pathways; Rats; Rats, Wistar; Scopolamine; Smell; Touch; Valine | 2017 |
Contribution of the basolateral amygdala NMDA and muscarinic receptors in rat's memory retrieval.
Topics: Animals; Basolateral Nuclear Complex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mental Recall; Muscarinic Antagonists; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Scopolamine; Valine | 2017 |
Disinhibition of the intergeniculate leaflet network in the WAG/Rij rat model of absence epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Epilepsy, Absence; Excitatory Amino Acid Antagonists; GABA Agents; Geniculate Bodies; Inhibitory Postsynaptic Potentials; Male; Nerve Net; Neural Inhibition; Neuropeptide Y; Rats; Rats, Mutant Strains; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin; Valine | 2017 |
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Algorithms; Animals; Carrier Proteins; Cells, Cultured; Computer Simulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABAergic Neurons; Hippocampus; Long-Term Synaptic Depression; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Peptides; Polymers; Post-Synaptic Density; Receptors, GABA-A; Valine | 2017 |
Temporally precise control of single-neuron spiking by juxtacellular nanostimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Biophysics; Cytoskeletal Proteins; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Luminescent Proteins; Male; Mice; Mice, Transgenic; Models, Neurological; Nerve Tissue Proteins; Neurons; Optogenetics; Patch-Clamp Techniques; Somatosensory Cortex; Synapsins; Time Factors; Valine | 2017 |
Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain.
Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation; Hyperalgesia; Male; Pain Threshold; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sciatica; Subcellular Fractions; Synaptic Transmission; Valine | 2017 |
Updating Procedures Can Reorganize the Neural Circuit Supporting a Fear Memory.
Topics: Amygdala; Animals; Anisomycin; Conditioning, Classical; Extinction, Psychological; Fear; Male; Memory; Memory Consolidation; Mental Recall; Rats; Valine | 2017 |
Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties.
Topics: Astrocytes; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioblastoma; Humans; Immunosuppressive Agents; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Nitric Oxide Synthase Type III; RNA, Messenger; Sirolimus; Time Factors; Up-Regulation; Valine | 2017 |
Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury.
Topics: Action Potentials; Animals; Brain Injuries, Traumatic; Diffuse Axonal Injury; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neocortex; Nerve Tissue Proteins; Neural Inhibition; Neural Pathways; Parvalbumins; Quinoxalines; Valine; Vesicular Inhibitory Amino Acid Transport Proteins | 2018 |
Chronic salt-loading reduces basal excitatory input to CRH neurons in the paraventricular nucleus and accelerates recovery from restraint stress in male mice.
Topics: Animals; Area Under Curve; Corticotropin-Releasing Hormone; Drinking; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Luminescent Proteins; Male; Mice; Mice, Transgenic; Mutation; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Quinoxalines; Recovery of Function; Restraint, Physical; RNA, Messenger; Salts; Sodium; Time Factors; Valine | 2017 |
Enhancing and impairing extinction of habit memory through modulation of NMDA receptors in the dorsolateral striatum.
Topics: Analysis of Variance; Animals; Antimetabolites; Corpus Striatum; Cycloserine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Extinction, Psychological; Habits; Male; Maze Learning; Memory; Rats; Rats, Long-Evans; Reaction Time; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2017 |
Synergistic effect between D-AP5 and muscimol in the nucleus accumbens shell on memory consolidation deficit in adult male Wistar rats: An isobologram analysis.
Topics: Animals; Bicuculline; Emotions; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Memory Consolidation; Motor Activity; Muscimol; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Valine | 2017 |
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Citrates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agents; In Vitro Techniques; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine; Vibrissae | 2017 |
Medial prefrontal cortex and dorsomedial striatum are necessary for the trial-unique, delayed nonmatching-to-location (TUNL) task in rats: role of NMDA receptors.
Topics: Animals; Cephalosporins; Choice Behavior; Ciprofloxacin; Conditioning, Operant; Corpus Striatum; Dose-Response Relationship, Drug; Male; Piperazines; Prefrontal Cortex; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Space Perception; Touch; Valine | 2017 |
Nicotinic activity depresses synaptic potentiation in layer V pyramidal neurons of mouse insular cortex.
Topics: Acetylcholine; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Cholinergic Agents; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Lysine; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Nicotine; Pyramidal Cells; Quinoxalines; Synaptic Potentials; Valine | 2017 |
Development of resurgent and persistent sodium currents in mesencephalic trigeminal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Biophysics; Excitatory Amino Acid Antagonists; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Tegmentum Mesencephali; Tetrodotoxin; Time Factors; Valine | 2018 |
Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain.
Topics: Analgesics; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Neurons; Pain Measurement; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalidomide; Valine | 2018 |
A Hypothalamic Leptin-Glutamate Interaction in the Regulation of Sympathetic Nerve Activity.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; Gene Knockdown Techniques; Glutamic Acid; Heart Rate; Hypothalamus; Kidney; Leptin; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sympathetic Nervous System; Valine | 2017 |
Developmental roles of the spontaneous depolarization wave in synaptic network formation in the embryonic brainstem.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Bicuculline; Brain Stem; Chick Embryo; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic Development; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glycine Agents; Neural Pathways; Strychnine; Synapses; Vagus Nerve; Valine | 2017 |
Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Cells, Cultured; DNA Methylation; Epigenesis, Genetic; Epilepsy; Excitatory Amino Acid Agents; Gene Expression; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Models, Biological; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Valine | 2017 |
Kainate receptor mediated presynaptic LTP in agranular insular cortex contributes to fear and anxiety in mice.
Topics: Animals; Anxiety; Cerebral Cortex; Conditioning, Classical; Disease Models, Animal; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agents; Exploratory Behavior; Fear; Glutamic Acid; Long-Term Potentiation; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Receptors, Kainic Acid; Synaptosomal-Associated Protein 25; Valine | 2018 |
The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Learning; Long-Term Potentiation; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Peptide Fragments; Protein Domains; Quinoxalines; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2018 |
Developmentally primed cortical neurons maintain fidelity of differentiation and establish appropriate functional connectivity after transplantation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Cell Adhesion Molecules, Neuronal; Cell Differentiation; DNA-Binding Proteins; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Nerve Tissue Proteins; Neurons; Repressor Proteins; Synaptophysin; Transcription Factors; Tumor Suppressor Proteins; Valine | 2018 |
CaMKII-dependent endoplasmic reticulum fission by whisker stimulation and during cortical spreading depolarization.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cortical Spreading Depression; Dendritic Spines; Electrocorticography; Endoplasmic Reticulum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Photobleaching; Physical Stimulation; Somatosensory Cortex; Statistics, Nonparametric; Time Factors; Valine; Vibrissae | 2018 |
Circuit-selective properties of glutamatergic inputs to the rat prelimbic cortex and their alterations in neuropathic pain.
Topics: Action Potentials; Animals; Animals, Newborn; Channelrhodopsins; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Hippocampus; Male; Nerve Net; Neural Inhibition; Neural Pathways; Neuralgia; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine | 2018 |
Metaplasticity contributes to memory formation in the hippocampus.
Topics: Animals; Conditioning, Classical; Excitatory Amino Acid Antagonists; Hippocampus; Male; Memory; Mice; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2019 |
Mechanisms of Spontaneous Electrical Activity in the Developing Cerebral Cortex-Mouse Subplate Zone.
Topics: Action Potentials; Animals; Bicuculline; Calcium Channel Blockers; Calcium Signaling; Cerebral Cortex; Citrates; Connexin 26; Connexins; Ependymoglial Cells; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gadolinium; Gap Junction beta-1 Protein; Gap Junction delta-2 Protein; Gap Junctions; Glycine Agents; Hexachlorocyclohexane; Lanthanum; Mice; Neuroglia; Neurons; Octanols; Patch-Clamp Techniques; Probenecid; Pyridoxal Phosphate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Strychnine; Valine; Vimentin | 2019 |
Noise-Induced Hypersensitization of the Acoustic Startle Response in Larval Zebrafish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Electric Stimulation; Larva; Noise; Quinoxalines; Receptors, AMPA; Reflex, Startle; Valine; Zebrafish | 2018 |
Na
Topics: Animals; Astrocytes; CA1 Region, Hippocampal; Cell Count; Cell Death; Cells, Cultured; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Transporter 1; In Vitro Techniques; Lithium Carbonate; Microglia; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase; Valine | 2018 |
Peculiarities of Participation of DNA Methyltransferases in the Mechanisms of Storage, Impairment, and Recovery of Conditioned Food Aversion Memory.
Topics: Amnesia; Animals; DNA Modification Methylases; Helix, Snails; Memory; Phthalimides; Receptors, N-Methyl-D-Aspartate; Tryptophan; Valine | 2018 |
G
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels, N-Type; Dopamine; Dopaminergic Neurons; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gene Expression; Guanosine Diphosphate; Ion Channels; Ion Transport; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtomy; Nerve Tissue Proteins; Patch-Clamp Techniques; Picrotoxin; Receptors, Dopamine D2; Receptors, GABA-B; Thionucleotides; Tissue Culture Techniques; Valine; Ventral Tegmental Area | 2018 |
Electrical stimulation mPFC affects morphine addiction by changing glutamate concentration in the ventral tegmental area.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Morphine; Morphine Dependence; Narcotics; Prefrontal Cortex; Rats; Rats, Wistar; Valine; Ventral Tegmental Area | 2019 |
NMDARs contribute to the facial stimuli-evoked mossy fiber-granule cell synaptic transmission in vivo in mice.
Topics: Animals; Cerebellar Cortex; Excitatory Amino Acid Antagonists; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Physical Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine; Vibrissae | 2020 |
Protein synthesis inhibitor administration before a reminder caused recovery from amnesia induced by memory reconsolidation impairment with NMDA glutamate receptor antagonist.
Topics: Amnesia; Animals; Avoidance Learning; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Helix, Snails; Memory Consolidation; Mental Recall; Protein Synthesis Inhibitors; Valine | 2021 |