2-amino-5-phosphonovalerate has been researched along with selfotel in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 22 (84.62) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bigge, CF; Drummond, JT; Humblet, C; Johnson, G; Malone, TC; Ortwine, DF; Pinter, GW | 1 |
| Harrison, BL; McDonald, IA; Weintraub, HJ; Whitten, JP | 1 |
| Chiorri, C; Cordi, AA; Dappen, MS; Monahan, JB; Natalini, B; Pellicciari, R | 1 |
| Baron, BM; McDonald, IA; Miller, F; Muench, D; White, HS; Whitten, JP | 1 |
| Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ | 1 |
| Chittur, S; Griffith, R | 1 |
| Nellgård, B; Wieloch, T | 1 |
| Dichter, MA; Molinoff, PB; Williams, K | 1 |
| Bonaventure, N; Jardon, B | 1 |
| Davies, J; Harris, NC | 1 |
| Ohno, M; Watanabe, S; Yamamoto, T | 1 |
| Rosenberg, PA | 1 |
| Weiss, S | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Boast, CA; Pastor, G | 1 |
| Payne, RS; Rigor, BM; Schurr, A | 1 |
| Fagg, GE; Massieu, L; McVey, M; Thedinga, KH | 1 |
| Allegrini, PR; Fagg, GE; Sauer, D | 1 |
| Hargreaves, RJ; Hill, RG; Iversen, LL; Rigby, M; Smith, D | 1 |
| Aizenman, E; Blitzblau, RC; Hartnett, KA; Rosenberg, PA; Speliotes, EK | 1 |
| Brandsgaard, RR; Clissold, DB; Ferkany, JW; Hamilton, GS; Hartman, TL; Willetts, J | 1 |
| Adan, J; Capdevila, JL; Martínez, JM; Piulats, J; Tarrason, G; Trullas, R; Zapata, A | 1 |
| Kohjimoto, Y; Kometani, M; Nakao, K; Okada, M; Takahashi, I; Tanaka, I; Ueda, H | 1 |
| Kometani, M; Nakao, K; Okada, M; Ueda, H | 1 |
| Brower, VG; Fu, Y; Gao, W; Matta, SG; Sharp, BM | 1 |
| Gemignani, A; Paudice, P; Pittaluga, A; Raiteri, M | 1 |
26 other study(ies) available for 2-amino-5-phosphonovalerate and selfotel
| Article | Year |
|---|---|
Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists.
Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1992 |
Modeling of competitive phosphono amino acid NMDA receptor antagonists.
Topics: Binding, Competitive; Computer Simulation; Electricity; Models, Molecular; Organophosphonates; Receptors, N-Methyl-D-Aspartate | 1992 |
Synthesis and biological evaluation of cyclopropyl analogues of 2-amino-5-phosphonopentanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Indicators and Reagents; Kainic Acid; Kinetics; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes; Tritium | 1991 |
(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.
Topics: Animals; Binding, Competitive; Cerebellum; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kindling, Neurologic; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 1990 |
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes | 1990 |
Multisubstrate analogue inhibitors of glucosamine-6-phosphate synthase from Candida albicans.
Topics: Binding Sites; Candida albicans; Enzyme Inhibitors; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) | 2002 |
NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cell Membrane Permeability; Cortical Spreading Depression; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Male; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1992 |
Up-regulation of N-methyl-D-aspartate receptors on cultured cortical neurons after exposure to antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 1992 |
N-methyl-D-aspartate antagonists suppress the development of frog symmetric monocular optokynetic nystagmus observed after unilateral visual deprivation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraperitoneal; Magnetics; Microinjections; N-Methylaspartate; Nystagmus, Physiologic; Pipecolic Acids; Rana esculenta; Receptors, N-Methyl-D-Aspartate; Vision, Monocular | 1992 |
Cortically evoked excitatory synaptic transmission in the cat red nucleus is antagonised by D-AP5 but not by D-AP7.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cats; Electric Stimulation; Neurons; Pipecolic Acids; Piperazines; Receptors, N-Methyl-D-Aspartate; Red Nucleus; Somatosensory Cortex; Synapses; Synaptic Transmission | 1992 |
Effects of intrahippocampal injections of N-methyl-D-aspartate receptor antagonists and scopolamine on working and reference memory assessed in rats by a three-panel runway task.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Male; Memory; N-Methylaspartate; Pipecolic Acids; Piperazines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1992 |
Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glutamates; Glutamic Acid; Glutamine; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Pharmacological properties of the N-methyl-D-aspartate receptor system coupled to the evoked release of gamma-[3H] aminobutyric acid from striatal neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Mice; Neurons; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors | 1987 |
Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anti-Anxiety Agents; Benzodiazepines; Diltiazem; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Neurons; Nifedipine; Pipecolic Acids; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
A comparative analysis of the neuroprotective properties of competitive and uncompetitive N-methyl-D-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biomarkers; Cell Death; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Drug Administration Schedule; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections; Injections, Intraperitoneal; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Pipecolic Acids; Piperazines; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
The competitive NMDA receptor antagonist CGP 40116 is a potent neuroprotectant in a rat model of focal cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Brain Ischemia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Magnetic Resonance Imaging; Male; Neuroprotective Agents; Pipecolic Acids; Piperazines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate | 1994 |
Competitive as well as uncompetitive N-methyl-D-aspartate receptor antagonists affect cortical neuronal morphology and cerebral glucose metabolism.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Cerebral Cortex; Glucose; Male; Neurons; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Dizocilpine Maleate; Embryo, Mammalian; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Behavioral pharmacology of NPC 17742, a competitive N-methyl-D-aspartate (NMDA) antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Binding, Competitive; Dose-Response Relationship, Drug; Isoquinolines; Male; Mice; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Effects of NMDA-R1 antisense oligodeoxynucleotide administration: behavioral and radioligand binding studies.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Behavior, Animal; Brain; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Oligonucleotides, Antisense; Pipecolic Acids; Radioligand Assay; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
Neuroprotective effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid in the gerbil model of transient global cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Excitatory Amino Acid Antagonists; Gerbillinae; Ischemic Attack, Transient; Male; Motor Activity; Neurons; Neuroprotective Agents; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate | 1997 |
Effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid on focal cerebral ischemia in cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cats; Cerebral Infarction; Excitatory Amino Acid Antagonists; Image Processing, Computer-Assisted; Male; Neuroprotective Agents; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate | 1997 |
Systemic nicotine stimulates dopamine release in nucleus accumbens: re-evaluation of the role of N-methyl-D-aspartate receptors in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Ventral Tegmental Area | 2000 |
The HIV-1 coat protein gp120 and some of its fragments potently activate native cerebral NMDA receptors mediating neuropeptide release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cholecystokinin; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; HIV Envelope Protein gp120; HIV-1; Indoles; Kynurenic Acid; Male; Maleimides; Neurons; Nitroarginine; Peptide Fragments; Pipecolic Acids; Piperazines; Piperidines; Potassium; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatostatin; Synaptic Transmission; Synaptosomes; Zinc | 2000 |