2-amino-5-phosphonovalerate has been researched along with n-methylaspartate in 934 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 163 (17.45) | 18.7374 |
| 1990's | 504 (53.96) | 18.2507 |
| 2000's | 180 (19.27) | 29.6817 |
| 2010's | 83 (8.89) | 24.3611 |
| 2020's | 4 (0.43) | 2.80 |
| Authors | Studies |
|---|---|
| Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Becker, DP; Hovda, DA; Katayama, Y; Kawamata, T; Yoshino, A | 1 |
| Colino, A; Huang, YY; Malenka, RC; Selig, DK | 1 |
| Jensen, TS; Yaksh, TL | 1 |
| de Waele, C; Khateb, A; Mühlethaler, M; Serafin, M; Vidal, PP | 1 |
| Davis, M; Falls, WA; Miserendino, MJ | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 1 |
| Dudek, FE; Peacock, WJ; Wuarin, JP | 1 |
| Sage, GP; Sethy, VH | 1 |
| Chapman, CD; Howard, S; Marek, P | 1 |
| Hisanaga, K; Sagar, SM; Sharp, FR | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Helm, SW; Henzi, V; MacDermott, AB; Reichling, DB | 1 |
| Dykstra, C; Gebhart, GF; Meller, ST | 1 |
| Clifford, DB; Izumi, Y; Zorumski, CF | 1 |
| Esguerra, M; Kwon, YH; Sur, M | 2 |
| Di Loreto, S; Florio, T; Scarnati, E | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 2 |
| Henry, JL; Hong, YG | 1 |
| Czepita, D; Daw, N; Fox, K; Sato, H | 1 |
| Chuang, DM; Gao, XM | 1 |
| Ishii, T; Masu, M; Moriyoshi, K; Nakanishi, S; Sugihara, H | 1 |
| Carrozza, DP; Ferraro, TN; Golden, GT; Hare, TA; Reyes, PF | 1 |
| Bonaventure, N; Jardon, B | 1 |
| Weiland, NG | 1 |
| Amano, T; Hishinuma, F; Kuwahara, R; Okabe, N; Ozawa, F; Yamakuni, T | 1 |
| Lu, CL; Shaikh, MB; Siegel, A | 1 |
| Constantine-Paton, M; Scherer, WJ; Udin, SB | 1 |
| Chen, Y; Graham, DI; Stone, TW | 1 |
| Flavin, MP; Riopelle, RJ; Yang, Y | 1 |
| Pinnock, RD | 1 |
| Kita, H; Nakanishi, H; Yamamoto, K | 1 |
| Rekling, JC | 1 |
| Cambray-Deakin, MA; Rashid, NA | 1 |
| Dingledine, R; McBain, C | 1 |
| Berrino, L; Lampa, E; Maione, S; Rossi, F; Vitagliano, S | 1 |
| Henry, JL; Hong, Y | 1 |
| Sekiguchi, M; Wada, K; Wenthold, RJ | 1 |
| Arnold, G; Klockgether, T; Kupsch, A; Oertel, W; Renner, P; Scheid, C; Scheid, R; Wüllner, U | 1 |
| Grover, LM; Teyler, TJ | 1 |
| Nicoll, RA; Zalutsky, RA | 1 |
| Ferko, AP | 1 |
| Kurusu, R; Sakurai, H; Sano, K; Tsuchiya, T; Tsuda, M | 1 |
| De Sarro, A; De Sarro, G; Meldrum, BS; Patel, S | 1 |
| Besser, GM; Costa, A; Forsling, ML; Grossman, A; Hucks, D; Yasin, SA | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB; Stratta, F | 1 |
| Holopainen, I; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Marini, AM; Paul, SM; Weller, M | 1 |
| Ohno, M; Watanabe, S; Yamamoto, T | 1 |
| Bramlett, D; Garrison, DT; Kinney, WA; Kowal, DM; Lee, NE; Notvest, RR; Podlesny, EJ; Simmonds, JT; Tasse, RP | 1 |
| Bronzetti, E; Caporali, MG; Frank, C; Niglio, T; Sagratella, S; Scotti de Carolis, A | 1 |
| Burger, RL; Jobe, PC; Lasley, SM; Ludvig, N; Mishra, PK; Yan, QS | 1 |
| Grigor'ev, VV; Nemanova, VA; Ragulin, VV | 1 |
| Russo, RE; Velluti, JC | 1 |
| Evans, PD; Merzon, RM; Reale, V; Villegas, J | 1 |
| Garrone, B; Pittaluga, A; Raiteri, M | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Beckstead, RM; Somers, DL | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Horii, A; Mochizuki, T; Okakura, K; Wada, H; Yamatodani, A | 1 |
| Gribkoff, VK; Lum-Ragan, JT | 1 |
| Bonhaus, DW; McNamara, JO | 1 |
| Conti, L; Ellenberger, SR; Ellenberger, WP; Ferkany, JW; Guzewska, ME; Hudkins, R; Kyle, DJ; Narayanan, BA; Patch, R; Rzeszotarski, WJ | 1 |
| Beninger, RJ; Jhamandas, K; Thanos, PK | 1 |
| Fragoso-Veloz, J; Tapia, R | 1 |
| Dreifuss, JJ; Raggenbass, M; Widmer, H | 1 |
| Arslan, M; Plant, TM; Pohl, CR; Smith, MS | 1 |
| Boje, K; Miller, R; Skolnick, P; Trullas, R; Young, A | 1 |
| Clark, D; Overton, P | 2 |
| Denavit-Saubie, M; Foutz, AS; Pierrefiche, O; Schmid, K | 1 |
| Malenka, RC | 1 |
| Chernevskaya, NI; Krishtal, OA; Obukhov, AG | 1 |
| DiMicco, JA; Soltis, RP | 1 |
| Hönack, D; Löscher, W | 1 |
| Hablitz, JJ; Lee, WL | 1 |
| Crane, AM; Driscoll, BF; Law, MJ | 1 |
| Aizenman, E; Lipton, SA; Sucher, NJ | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Frenguelli, BG | 1 |
| Klunk, WE; McClure, RJ; Pettegrew, JW | 1 |
| Kihara, M; Kubo, T; Misu, Y | 1 |
| Chabert, R; Eybalin, M; Ladrech, S; Puel, JL; Pujol, R | 1 |
| Ceccaldi, PE; Ermine, A; Guillemer, S; Lockhart, B; Tsiang, H | 1 |
| Frye, GD | 1 |
| Hahm, JO; Langdon, RB; Sur, M | 1 |
| Nishikawa, T; Ohi, K; Takahashi, K; Takashima, M | 1 |
| Anderton, PJ; Millar, TJ | 1 |
| Scherer, WJ; Udin, SB | 2 |
| Rosenberg, PA | 1 |
| Houk, JC; Keifer, J | 1 |
| Dougherty, PM; Willis, WD | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Chronister, RB; Joshi, RS; Marco, LA | 1 |
| Bandopadhyay, R; de Belleroche, J | 1 |
| Dreyer, EB; Kaiser, PK; Lipton, SA; Sucher, NJ | 1 |
| Clark, AJ; Hastings, MH; Latimer, M; Stone, TW; Winn, P | 1 |
| Sapru, H; Sundaram, K | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Fassbender, CP; Hönack, D; Löscher, W | 1 |
| Dodt, HU; Pawelzik, H; Zieglgänsberger, W | 1 |
| Chetkovich, DM; Gray, R; Johnston, D; Sweatt, JD | 1 |
| Curran, GH; Feder, HH; McCarthy, MM | 1 |
| Baev, KV; Chub, NL | 1 |
| Turner, DA; Wheal, HV | 1 |
| Cline, HT; Constantine-Paton, M; Debski, EA; McDonald, JW | 1 |
| Kannari, K; Markstein, R | 1 |
| Eysel, UT; FitzGibbon, T; Funke, K | 1 |
| Rawlins, JN; Tonkiss, J | 1 |
| Onodera, K; Takeuchi, A | 1 |
| Akerman, KE; Holopainen, I; Louve, M | 1 |
| Daniell, LC | 1 |
| Collins, GG | 2 |
| Delrée, P; Lefebvre, PP; Leprince, P; Moonen, G; Rigo, JM; Rogister, B; Weber, T | 1 |
| Fink, K; Göthert, M | 2 |
| Schmidt, M | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Paton, JF; Rogers, WT; Schwaber, JS | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ | 1 |
| Oja, SS; Saransaari, P | 1 |
| Li, J; Smith, SS | 1 |
| Morita, Y; Nishimura, S; Sorimachi, M | 1 |
| Coderre, TJ; Melzack, R | 1 |
| Jean, A; Kessler, JP | 1 |
| Cherubini, E; Kilić, G; Moran, O | 1 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Fukushima, R; Kizu, A; Miyagishi, T; Ono, T; Yoshida, Y | 1 |
| Cerne, R; Gerber, G; Randić, M | 1 |
| Christenson, J; Grillner, S | 1 |
| Coulter, DA; DeLorenzo, RJ; Sombati, S | 1 |
| Rigor, BM; Schurr, A; West, CA | 1 |
| Billard, JM; Daniel, H; Pumain, R | 1 |
| Guy, N; Ropert, N | 1 |
| Ohmori, H; Yamaguchi, K | 1 |
| Finch, DM; Fisher, RS; Jackson, MB | 1 |
| Daló, NL; Larson, AA | 1 |
| McMillian, M; Miller, LG; Schatzki, A | 1 |
| Kisara, K; Manome, Y; Sakurada, S; Sakurada, T; Tan-No, K | 1 |
| Fields, RD; Nelson, PG; Yu, C | 1 |
| Gündel, J; Matthies, H; Steinhäuser, C | 1 |
| Cline, HT; Tsien, RW | 1 |
| Kawai, N; Robinson, HP; Sahara, Y | 1 |
| Cowan, A; Larson, AA; Murray, CW | 1 |
| Bigalke, H; Lampe, H | 1 |
| Larson, AA; Sun, XF | 1 |
| Franke, C; Hatt, H; Rosenheimer, JL; Smith, DO; Zufall, F | 1 |
| Arancio, O; MacDermott, AB; Murase, K; Yoshimura, M | 1 |
| Linn, DM; Massey, SC | 1 |
| Chai, CY; Kao, MC; Lee, HK; Wang, Y | 1 |
| Insel, TR; Skolnick, P; Trullas, R; Winslow, JT | 1 |
| Brehm, L; Jørgensen, FS; Krogsgaard-Larsen, P; Madsen, U; Schaumburg, K | 1 |
| Ohno, Y; Warnick, JE | 1 |
| Grudt, TJ; Jahr, CE | 1 |
| Anderson, EG; Grigg, JJ | 1 |
| Adams, PR; Guido, W; Lu, SM; Scharfman, HE; Sherman, SM | 1 |
| Dresse, A; Massotte, L; Seutin, V; Verbanck, P | 1 |
| Benveniste, M; Mayer, ML; Mienville, JM; Sernagor, E | 1 |
| Davis, M; Melia, KR; Miserendino, MJ; Sananes, CB | 1 |
| Markram, H; Segal, M | 1 |
| Okamoto, K; Sakai, Y; Sekiguchi, M | 1 |
| Clements, JD; Jahr, CE; Lester, RA; Westbrook, GL | 1 |
| Akaike, N; Murase, K; Nakagawa, T; Shirasaki, T; Tateishi, N | 1 |
| Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA | 1 |
| Becquet, D; Faudon, M; Hery, F | 1 |
| Raigorodsky, G; Urca, G | 3 |
| Fink, K; Göthert, M; Schlicker, E | 1 |
| Reymann, KG; Schröder, H | 1 |
| Chaki, S; Muramatsu, M; Otomo, S; Usuki-Ito, C | 1 |
| Dun, NJ; Mo, N; Shen, E | 1 |
| Hestrin, S; Nicoll, RA; Perkel, DJ; Sah, P | 1 |
| Egert, U; Kossel, A; Rauschecker, JP | 1 |
| Buchwald, NA; Cepeda, C; Dudek, FE; Kim, YI; Peacock, WJ; Tasker, JG; Walsh, JP; Wuarin, JP | 1 |
| Aizenman, E; Loring, RH; Rosenberg, PA; White, WF | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Dingledine, R; McNamara, D | 1 |
| Boksa, P; Chaudieu, I; Mount, H; Quirion, R | 1 |
| Mitchell, D; Sher, GD | 1 |
| Urca, G; Urca, R | 1 |
| Hata, N; Nishikawa, T; Takahashi, K; Umino, A | 1 |
| Cordi, AA; Monahan, JB; Reisse, J | 1 |
| Khaspekov, LG; Lisý, V; Stastný, F; Viktorov, IV | 1 |
| Gross, GW; Lucas, JH; Wang, GF | 1 |
| Nag, S; Riopelle, RJ | 1 |
| Jean, A; Tell, F | 1 |
| Mohri, T; Suzuki, R; Takadera, T | 1 |
| Audinat, E; Gähwiler, BH; Knöpfel, T | 1 |
| Hoehn, K; White, TD | 1 |
| Chiamulera, C; Costa, S; Reggiani, A | 1 |
| Dow, KE; Riopelle, RJ | 1 |
| Liu, GQ; Ping, HX; Wu, HQ | 1 |
| Massey, SC; Miller, RF | 1 |
| Girault, JA; Greengard, P; Halpain, S | 1 |
| Butler, TW; Butterfield, GC; Chenard, BL; Dominy, BW; Lipinski, CA; Marinovic, LC; Mena, EE; Pagnozzi, M; Ronau, RT; Tsang, T | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Halsey, MJ; Meldrum, BS; Millan, MH; Wardley-Smith, B | 2 |
| Gonzales, RA; Woodward, JJ | 1 |
| Biesterfeldt, JP; Compton, RP; Cordi, AA; Hood, WF; Lanthorn, TH; Monahan, JB; Vazquez, MI; Wood, PL | 1 |
| Coenen, AM; Peeters, BW; van Rijn, CM; Vossen, JM | 1 |
| Baker, RE; Ruijter, JM | 1 |
| Akerman, KE; Holopainen, I | 1 |
| Jope, RS; Li, X; Ormandy, GC | 1 |
| Rogers, BC; Tilson, HA | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Fischbach, GD; O'Brien, RJ | 1 |
| Cherubini, E; King, AE; Nistri, A | 1 |
| Moran, J; Patel, AJ | 1 |
| Buerki, H; Fagg, GE; Mondadori, C; Petschke, F; Weiskrantz, L | 1 |
| Buckley, KS; Collins, GG | 1 |
| Bartkowski, H; Roman, R; Simon, R | 1 |
| Chambers, G; Cottrell, JE; Kass, IS | 1 |
| Haberly, LB; Hoffman, WH | 1 |
| Dudek, S; Joly, M; Lynch, G; Muller, D; Schottler, F; Thibault, O | 1 |
| Clow, DW; Jhamandas, K | 1 |
| Girdlestone, D; Thomson, AM; West, DC | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| Chandler, SH | 1 |
| Greenberg, JH; Karp, A; Reivich, M; Uematsu, D | 1 |
| Ogita, K; Yoneda, Y | 1 |
| Hablitz, JJ; Sutor, B | 1 |
| Brugger, F; Olpe, HR; Pozza, MF; Steinmann, MW | 1 |
| Pierson, MG; Smith, KL; Swann, JW | 1 |
| Chapman, B; Miller, KD; Stryker, MP | 1 |
| Akoev, GN; Andrianov, IuN; Bromm, B; Sabo, T; Sherman, NO | 1 |
| Choi, DW; Hartley, DM | 1 |
| Dun, NJ; Minota, S; Miyazaki, T; Read, HL; Wang, MY | 1 |
| Anderson, WW; Clark, S; Stasheff, SF; Wilson, WA | 1 |
| Caspary, DM; Faingold, CL; Hoffmann, WE | 1 |
| Bowe, MA; Martin, D; Nadler, JV | 1 |
| Aizenman, E; Rosenberg, PA | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| Miyachi, E; Murakami, M | 1 |
| Dildy, JE; Leslie, SW | 1 |
| Rakić, L; Shupliakov, OV; Supljakov, OV; Veskov, R; Vesselkin, NP | 1 |
| Bieger, D; Hashim, MA | 1 |
| Itzhak, Y | 1 |
| Dye, J; Heiligenberg, W; Kawasaki, M; Keller, CH | 1 |
| Hestrin, S; Nicoll, RA; Sah, P | 1 |
| Benedetti, M; Frank, C; Sagratella, S; Scotti de Carolis, A | 1 |
| Cherniack, NS; Mitra, J; Overholt, JL; Prabhakar, NR | 2 |
| Smith, SS | 1 |
| Gallagher, JP; Hasuo, H | 1 |
| Avanzini, G; de Curtis, M; Spreafico, R | 1 |
| Choi, DW; Goldberg, MP; Monyer, H; Tecoma, ES | 1 |
| Cline, HT; Constantine-Paton, M | 1 |
| Ben-Ari, Y; Cherubini, E; King, AE | 1 |
| McCaslin, PP; Morgan, WW | 3 |
| Evans, MC; Meldrum, BS; Swan, JH | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Wamil, A | 1 |
| Arslan, M; Plant, TM; Pohl, CR | 1 |
| De Prins, E; Marrannes, R; Wauquier, A; Willems, R | 1 |
| Jacquet, YF; Squires, RF | 1 |
| Jacquet, YF | 1 |
| Collins, JF; Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Gibson, BL; Reif-Lehrer, L | 1 |
| Cunningham, JR; Neal, MJ | 1 |
| Lukasiewicz, PD; McReynolds, JS | 1 |
| Lodge, D; Martin, D | 2 |
| Hablitz, JJ | 1 |
| Martin, MR | 1 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| Carpenter, DO; Ffrench-Mullen, JM; Hori, N | 2 |
| Curry, K; Magnuson, DS; McLennan, H; Peet, MJ | 1 |
| Canning, HM; Leach, MJ; Marden, CM | 1 |
| Collins, KJ; Wheatley, PL | 1 |
| Collins, JF; Stone, TW | 1 |
| Gregersen, H; McLennan, H; Peet, MJ | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Koek, W; Ornstein, P; Woods, JH | 1 |
| Stone, TW | 1 |
| Davies, J; Evans, RH; Herrling, PL; Jones, AW; Olverman, HJ; Pook, P; Watkins, JC | 1 |
| Dragunow, M; Goddard, GV; Morimoto, K | 1 |
| De Belleroche, JS; Gardiner, IM; Hamilton, MH; Herberg, LJ | 1 |
| King, AE; Nistri, A | 1 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Johnson, KM; Jones, SM; Snell, LD | 2 |
| Ballanyi, K; Endres, W; Grafe, P; Serve, G | 1 |
| Gordon, FJ | 1 |
| Fagg, GE; Foster, AC | 1 |
| Anderson, WW; Swartzwelder, HS; Wilson, WA | 1 |
| Gustafsson, B; Wigström, H | 1 |
| Ito, K; Izumi, Y; Kato, H; Kudo, Y; Miyakawa, H; Ogura, A | 1 |
| Avoli, M; Olivier, A | 1 |
| Cline, HT; Constantine-Paton, M; Debski, EA | 1 |
| Foster, AC; Wong, EH | 1 |
| Crepel, F; Dupont, JL; Gardette, R | 1 |
| Drejer, J; Honoré, T; Schousboe, A | 1 |
| Lees, GJ | 1 |
| Cherniack, NS; Deal, EC; Haxhiu, MA; Norcia, MP; Strohl, KP; van Lunteren, E | 1 |
| Crunelli, V; Kelly, JS; Leresche, N; Pirchio, M | 1 |
| de Carolis, AS; Frank, C; Sagratella, S | 1 |
| Samanin, R; Vezzani, A; Wu, HQ | 1 |
| Bockaert, J; Kemp, DE; Schmidt, BH; Sebben, M; Sladeczek, F; Weiss, S | 1 |
| Barry, MJ; O'Donovan, MJ | 1 |
| Choi, DW; Koh, JY; Peters, S | 1 |
| Aram, JA; Lodge, D | 1 |
| Childs, AM; Evans, RH; Watkins, JC | 1 |
| Caudle, RM; Isaac, L | 2 |
| Burton, NR; Smith, DA; Stone, TW | 1 |
| Beart, PM; Headley, PM; Nicolopoulos, LS; West, DC | 1 |
| Choi, DW; Coulter, DA; Prince, DA; Wong, BY | 1 |
| Ambar, I; Kloog, Y; Sokolovsky, M | 1 |
| Bockaert, J; Pin, JP; Van-Vliet, BJ | 1 |
| Connick, JH; Stone, TW | 1 |
| Carter, CJ; L'Heureux, R; Scatton, B | 1 |
| Pastuszko, A; Wilson, DF | 1 |
| Nishizaki, T; Okada, Y | 1 |
| Lopes da Silva, FH; Melchers, BP; Pennartz, CM; Wadman, WJ | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Fletcher, EJ; Lodge, D | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| King, AE; Thompson, SW; Urban, L; Woolf, CJ | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Mayer, ML; Vyklický, L; Westbrook, GL | 1 |
| Ben-Ari, Y; Cherubini, E; Neuman, R | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Lynch, G; Muller, D | 1 |
| Burton, NR; Smith, DA; Stone, TW; Williams, TL | 2 |
| Coleman, PA; Miller, RF | 1 |
| Kapetanovic, IM; Kupferberg, HJ; Torchin, CD; Yonekawa, WD | 1 |
| Beart, PM; Davies, SN; Jones, MG; Lodge, D; Manallack, DT; Millar, J; Ornstein, PL; Verberne, AJ; Young, N | 1 |
| Linden, DJ; Routtenberg, A; Sheu, FS; Wong, KL | 1 |
| Lauritzen, M; Nicholson, C; Okada, Y; Rice, ME | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Baudry, M; Jung, MW; Larson, J; Lynch, G; Oliver, M; Seubert, P | 1 |
| Ben-Ari, Y; Corradetti, R; Gaïarsa, JL | 1 |
| Armstrong-James, M; Fox, K | 1 |
| Wieloch, T | 1 |
| Cavalheiro, EA; Meldrum, BS; Turski, L; Turski, WA | 1 |
| Ho, PM; Tang, AH | 1 |
| Cherubini, E; Herrling, PL; Lanfumey, L; Stanzione, P | 1 |
| Balster, RL; Willetts, J | 1 |
| Compton, RP; Contreras, PC; Monahan, JB; O'Donohue, TL | 1 |
| Do, KQ; Herrling, PL; Turski, WA | 1 |
| Boast, CA; Pastor, G | 1 |
| Balm, M; Coyle, JT; Markl, A; Zaczek, R | 1 |
| Davies, J; Francis, AA; Jones, AW; Watkins, JC | 1 |
| Evans, RH; Watkins, JC | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 1 |
| Collins, JF; Curry, K; Labruyere, J; Olney, JW | 1 |
| Close, JM; Loewy, AD; Neil, JJ | 1 |
| Lehmann, J; Scatton, B | 1 |
| Eng, P; Hösli, E; Hösli, L; Lehmann, R | 1 |
| Collingridge, GL; Kehl, SJ; McLennan, H | 1 |
| Crunelli, V; Forda, S; Kelly, JS | 1 |
| Collins, JF; Croucher, MJ; Curry, K; Czuczwar, SJ; Joseph, M; Meldrum, BS; Stone, TW | 1 |
| Joëls, M; Urban, IJ | 1 |
| McLennan, H | 1 |
| Mayer, ML; Westbrook, GL | 1 |
| Czuczwar, SJ; Meldrum, B | 1 |
| Perkins, MN; Stone, TW | 2 |
| Collins, JF; Perkins, MN; Stone, TW | 1 |
| Chandler, SH; Kim, YI | 1 |
| Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Jahr, CE; Tong, G | 1 |
| Block, F | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R; Tribillac, F | 1 |
| Biggs, CS; Fowler, LJ; Richards, DA; Whitton, PS | 1 |
| Mikuni, M; Saitoh, K; Shinno, H; Takahashi, K; Tomita, U; Yamawaki, S | 1 |
| Kakuyama, M; Miyawaki, I; Mori, K; Nakamura, K; Terasako, K; Toda, H | 1 |
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| Campagnola, M; Cominacini, L; Crespi, F; Fratta-Pasini, A; Garbin, U; Gaviraghi, G; McMillan, K; Neudeck, A; Pastorino, A; Reggiani, A; Rossetti, Z | 1 |
| Ai, J; Jardemark, KE; Ninan, I; Wang, RY | 1 |
| Cepeda, C; Hurst, RS; Levine, MS; Shumate, LW | 1 |
| Huang, L; Pallas, SL | 1 |
| Morgan, SL; Teyler, TJ | 1 |
| Schoppa, NE; Westbrook, GL | 1 |
| Chenu, C; Espinosa, L; Itzstein, C | 1 |
| Asai, M; Isejima, H; Jonouchi, M; Kobayashi, M; Moriya, T; Okamura, H; Shibata, S; Yamaguchi, S | 1 |
| Li, YF; Mayhan, WG; Patel, KP | 1 |
| Alcocer, I; Bermúdez-Rattoni, F; Escobar, ML | 1 |
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| Gray, R; Johnston, D; Liang, Y; Yuan, LL | 1 |
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| de Graan, PN; Gispen, WH; Kamal, A; Ramakers, GM; Ruiter, B; van Dam, EJ | 1 |
| Coşkun, U; Gülay, S | 1 |
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| Genever, PG; Gu, Y; Publicover, SJ; Skerry, TM | 1 |
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| Feroah, TR; Forster, HV; Fuentes, CG; Hodges, M; Martino, P; Pan, L; Rice, T; Wenninger, J | 1 |
| Abdel-Rahman, AA; Zhang, J | 1 |
| Contestabile, A; Marri, L; Monti, B | 1 |
| Behnisch, T; Jäger, T; Reymann, KG | 1 |
| Gong, CL; Kuo, JS; Lin, NN | 1 |
| Wu, E | 1 |
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| Iino, M; Kakegawa, W; Ozawa, S; Tsuzuki, K | 1 |
| Lin, TB | 2 |
| Amamoto, T; Ando, S; Fujiwara, M; Nakanishi, H; Okada, M; Urae, R; Yazawa, K | 1 |
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| Futai, K; Hayashi, Y; Lashuel, HA; Lo, I; Nakagawa, T; Okamoto, K; Sheng, M; Walz, T | 1 |
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| Hori, K; Kobayashi, M; Masaki, T; Masuo, Y; Miyamoto, M; Noguchi, H; Nomura, M; Takamatsu, K; Tsubokawa, H | 1 |
| Aniksztejn, L; Ben-Ari, Y; Demarque, M; Jorquera, I; Manent, JB; Pellegrino, C; Represa, A | 1 |
| Anderson, AJ; Garraway, SM; Mendell, LM | 1 |
| Ellis-Davies, GC; Kasai, H; Matsuzaki, M; Noguchi, J | 1 |
| Auberson, YP; Baumgart, JP; Kim, MJ; McCormack, SG; Osten, P; Pak, D; Qin, Y; Sheng, M; van Aelst, L; Velamoor, V; Zhu, JJ; Zhu, Y | 1 |
| Ahmed, T; Frey, JU | 1 |
| Boeck, CR; Bronzatto, MJ; Jardim, FM; Kroth, EH; Souza, DO; Vendite, D | 1 |
| Hvalby, Ø; Jensen, V; Köhr, G; Kvello, A; Pawlak, V; Schupp, BJ; Seeburg, PH | 1 |
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| Grillner, S; Hill, RH; Tsvyetlynska, NA | 1 |
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| Cowley, KC; Maclean, JN; Schmidt, BJ; Zaporozhets, E | 1 |
| Djahanguiri, B; Jafari-Sabet, M; Rezayat, M; Rezayof, A; Zarrindast, MR | 1 |
| Azambuja, NA; Breda, RV; da Costa, JC; de Abreu, DS; Konno, K; Neto, EP; Nihei, K; Palma, MS; Salamoni, SD; Tavares, AA; Venturin, GT | 1 |
| Laute, MA; Manto, M; Pandolfo, M | 1 |
| Bito, H; Iki, J; Inoue, A; Okabe, S | 1 |
| Imai, K; Iwase, K; Kai, N; Kobayashi, K; Koga, H; Nakahira, E; Ohtsuka, S; Soma, M; Takiguchi, M; Yagi, T; Yuasa, S | 1 |
| Clements, JM; Vanhoose, AM; Winder, DG | 1 |
| Bayer, KU; De Koninck, P; LeBel, E; McDonald, GL; O'Leary, H; Schulman, H | 1 |
| Kanno, T; Maruo, K; Maruo, S; Nishizaki, T; Yaguchi, T; Yamamoto, S; Yashiya, S | 1 |
| Alavez, S; Blancas, S; Morán, J | 1 |
| Addae, JI; Stone, TW; Youssef, FF | 1 |
| Dell'Acqua, ML; Gibson, ES; Smith, KE | 1 |
| Cohen, AS; Geddes-Klein, DM; Meaney, DF; Mesfin, MN; Serbest, G | 1 |
| Baudry, M; Zhou, M | 1 |
| Chen, GD; Chen, JC; Chen, MJ; Ho, YC; Huang, PC; Liao, JM; Lin, JJ; Lin, SY; Lin, TB; Pan, SF; Peng, HY | 1 |
| Joo, DT; Zhao, M | 1 |
| Dai, T; Liu, H; Yao, S | 1 |
| Crowe, SL; Jorgensen, TJ; Kondratyev, A; Movsesyan, VA | 1 |
| Adkisson, M; Braithwaite, SP; Leung, J; Masterson, B; Nava, A; Nikolich, K; Oksenberg, D; Urfer, R | 1 |
| Jackson, KL; Li, YF; Patel, KP; Rabeler, B; Stern, JE | 1 |
| Yonehara, N; Yoshimura, M | 1 |
| Bertoglio, LJ; Guimarães, FS; Zangrossi, H | 1 |
| Bertoglio, LJ; Zangrossi, H | 1 |
| Chrapusta, SJ; Kaczyńska, K; Szereda-Przestaszewska, M | 1 |
| Carpenter-Hyland, EP; Chandler, LJ | 1 |
| Inoue, H; Okada, Y | 1 |
| Butler, TR; Ghayoumi, L; Holley, RC; Littleton, JM; Mullins, MM; Prendergast, MA; Self, RL; Smith, KJ | 1 |
| Aalkjaer, C; Bek, T; Hessellund, A; Holmgaard, K; Lambert, JD | 1 |
| Błasiak, A; Lewandowski, MH; Pekala, D | 1 |
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| Hsu, KS; Huang, CC | 1 |
| Chen, H; Sharp, BM; Wang, F | 1 |
| Aalkjaer, C; Bek, T; Holmgaard, K; Lambert, JD | 1 |
| Chen, GD; Chen, SL; Cheng, CL; Huang, PC; Huang, YH; Kao, YL; Liao, JM; Lin, TB; Peng, HY; Tsai, SJ | 1 |
| Gonzalo-Gobernado, R; Gonźlez-Vigueras, JM; Herranz, AS; Rodríguez-Navarro, JA; Solís, JM | 1 |
| Farb, DH; Gibbs, TT; Whittaker, MT | 1 |
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| Argilli, E; Bonci, A; England, PM; Malenka, RC; Sibley, DR | 1 |
| Bennett, MV; Rodenas-Ruano, A; Takayasu, Y; Takeuchi, K; Yang, Y; Zukin, RS | 1 |
| Dybała, M; Nowak, G; Pilc, A; Poleszak, E; Siwek, A | 1 |
| Dringenberg, HC; Habib, D | 1 |
| Heinmiller, A; Ting-A-Kee, R; van der Kooy, D; Vargas-Perez, H; Yeh, A | 1 |
| de Menezes, RC; DiMicco, JA; Fontes, MA; Zaretsky, DV | 1 |
| Cohen, D; Segal, M | 1 |
| Blankenship, AG; Copenhagen, DR; Edwards, RH; Feller, MB; Ford, KJ; Johnson, J; Seal, RP | 1 |
| Hu, XD; Liu, XH; Xie, QJ; Yang, HB; Yang, X | 1 |
| Chen, BS; Roche, KW | 1 |
| Cartier, AE; Djakovic, SN; Masliah, E; Patrick, GN; Salehi, A; Wilson, SM | 1 |
| Cairns, BE; Dong, XD; Svensson, P | 1 |
| Berry, JN; Butler, TR; Littleton, JM; Mulholland, PJ; Pauly, JR; Prendergast, MA; Self, RL; Sharrett-Field, LJ; Smith, KJ | 1 |
| Armand, V; Arrang, JM; Bayard, C; Burban, A; Faucard, R; Vorobjev, V | 1 |
| Dringenberg, HC; Hager, AM | 1 |
| Huang, LT; Lodge, D; Sherwood, JL; Sun, YJ; Wang, Y | 1 |
| Abbas, AK; Afanasenkau, D; Huang, FS; Li, R; Wigström, H | 1 |
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| Chari, M; Cheung, GW; Kokorovic, A; Lai, TY; Lam, CK; Lam, TK; Su, BB; Wang, PY; Yang, CS | 1 |
| Dergacheva, O; Jameson, H; Lovett-Barr, MR; Mendelowitz, D; Wang, X | 1 |
| Gire, DH; Pandipati, S; Schoppa, NE | 1 |
| Brandão, ML; Coimbra, NC; Ferrari, EA; Francisco, A; Maisonnette, SS; Medeiros, P; Mello, RO; Melo, LL; Santos, P | 1 |
| Bevins, RA; Murray, JE; Polewan, RJ; Walker, AW | 1 |
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| Ardjmand, A; Rezayof, A; Zarrindast, MR | 1 |
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| Hall, BJ; Patrick, GN; Schwarz, LA | 1 |
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| Aguirre, CA; English, BK; Lazar, L; Meals, E; Rayburn, MS; Shapley, RK; Spentzas, T; Walker, BS | 1 |
| Colledge, WH; d'Anglemont de Tassigny, X; Herbison, AE; Liu, X; Millar, R; Petersen, SL; Porteous, R | 1 |
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| Deng, Q; Fellin, T; Haydon, PG; Moss, SJ; Terunuma, M | 1 |
| Bai, Y; Chen, L; Li, L; Qi, J; Qi, Z; Sun, K; Yang, R; Zhang, Z; Zhou, L | 1 |
| Day, M; Plotkin, JL; Surmeier, DJ | 1 |
| Baudry, M; Chen, JC; Davis, DA; Finch, CE; Hsu, YT; Iwata, N; Kam, W; Morgan, TE; Ning, Z; Petasis, NA; Sioutas, C; Snyder, D; Tanner, JA; Winkler, JW | 1 |
| Izumi, Y; Tokuda, K; Zorumski, CF | 1 |
| Ahmadi, S; Ghiasvand, M; Rezayof, A; Zarrindast, MR | 1 |
| Aghamohammadi-Sereshki, A; Rezayof, A; Rostami, P; Zarrindast, MR | 1 |
| Liu, X; Llewellyn, T; Patel, KP; Xu, B; Zheng, H | 1 |
| Coccurello, R; Mele, A; Oliverio, A | 1 |
| Chen, JP; Hsu, KS; Huang, CC; Yeh, CM | 1 |
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| Ardiles, A; Guo, Y; He, K; Huang, S; Huganir, R; Kirkwood, A; Palacios, A; Pasquale, Rd; Treviño, M | 1 |
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| Albani, M; Chatzisotiriou, A; Kapoukranidou, D; Kouvelas, D; Petsanis, K; Simeonidou, C | 1 |
| Chen, K; Li, J; Song, L; Sun, B; Sun, H; Wei, X; Yan, J; Zhang, Y; Zhao, S; Zhao, X | 1 |
| Xie, G; Ye, JH | 1 |
| Bach, EC; Smith, BN | 1 |
| Barbosa-Silva, R; Iacopucci, AP; Mello, RO; Melo-Thomas, L | 1 |
| Berry, JN; Butler, TR; Prendergast, MA; Sharrett-Field, LJ | 1 |
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| Ahmad, F; Blaesse, P; Kaila, K; Puskarjov, M | 1 |
| Casanova, JE; Conger, KK; Myers, KR; Sheng, Y; Wang, G; Zhu, JJ | 1 |
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| Kazmierska, P; Konopacki, J | 1 |
| Antošová, M; Strapková, A | 1 |
| Hosseini, N; Nasehi, M; Radahmadi, M; Zarrindast, MR | 1 |
| Nowak, G; Pilc, A; Poleszak, E; Popik, P; Siwek, A; Szewczyk, B; Wolak, M | 1 |
| Chen, H; Matta, SG; Roguski, EE; Sharp, BM | 1 |
| Chen, D; Ding, L; Gao, R; Gao, XY; Kang, YM; Wang, JJ; Zhang, LL; Zhu, GQ | 1 |
| Dudka, J; Oniszczuk, T; Poleszak, E; Serefko, A; Szopa, A; Wlaź, P; Wośko, S; Wróbel, A | 1 |
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| Chang, JC; Chang, WP; Chen, IM; Cheng, JK; Chiu, HF; Lin, CH; Lin, CI; Lin, PH | 1 |
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1 review(s) available for 2-amino-5-phosphonovalerate and n-methylaspartate
| Article | Year |
|---|---|
On the excitatory post-synaptic potential evoked by stimulation of the optic tract in the rat lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aminobutyrates; Animals; Aspartic Acid; Calcium; Dipeptides; Glutamates; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Optic Nerve; Rats; Rats, Inbred Strains; Synapses; Thalamic Nuclei; Valine | 1987 |
1 trial(s) available for 2-amino-5-phosphonovalerate and n-methylaspartate
| Article | Year |
|---|---|
Aspartate and glutamate modulation of growth hormone secretion in the pig: possible site of action.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Aspartic Acid; Body Weight; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; N-Methylaspartate; Ovariectomy; Pituitary Gland, Anterior; Serum Albumin; Swine | 1996 |
932 other study(ies) available for 2-amino-5-phosphonovalerate and n-methylaspartate
| Article | Year |
|---|---|
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes | 1990 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Brain Concussion; Dialysis; Energy Metabolism; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ions; Kynurenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
The influence of prior synaptic activity on the induction of long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Electrophysiology; Hippocampus; N-Methylaspartate; Neuronal Plasticity; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1992 |
The antinociceptive activity of excitatory amino acids in the rat brainstem: an anatomical and pharmacological analysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Mapping; Brain Stem; Diencephalon; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Medulla Oblongata; Mesencephalon; Microinjections; N-Methylaspartate; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Reticular Formation; Stereotaxic Techniques | 1992 |
Medial vestibular nucleus in the guinea-pig: NMDA-induced oscillations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Stem; Cerebral Ventricles; Choline; Electric Conductivity; Evoked Potentials; Guinea Pigs; In Vitro Techniques; N-Methylaspartate; Neurons; Sodium; Tetrodotoxin | 1992 |
Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Brain Mapping; Dose-Response Relationship, Drug; Fear; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Reflex, Startle | 1992 |
The effects of excitatory amino acids on proenkephalin and prodynorphin mRNA levels in the hippocampal dentate gyrus of the rat; an in situ hybridization study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Enkephalins; Functional Laterality; Gene Expression; Hippocampus; Kainic Acid; Kinetics; Male; Microinjections; N-Methylaspartate; Nucleic Acid Hybridization; Protein Precursors; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
Single-electrode voltage-clamp analysis of the N-methyl-D-aspartate component of synaptic responses in neocortical slices from children with intractable epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Aging; Bicuculline; Cerebral Cortex; Child; Child, Preschool; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Female; Humans; Infant; Male; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Quinoxalines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1992 |
Modulation of release of acetylcholine from the striatum by a proposed excitatory amino acid antagonist U-54494A: comparison with known antagonists, diazepam and phenytoin.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Anticonvulsants; Corpus Striatum; Diazepam; Dizocilpine Maleate; In Vitro Techniques; N-Methylaspartate; Phencyclidine; Phenytoin; Potassium; Pyrrolidines; Rats | 1992 |
The effect of phencyclidine and DL-2-amino-5-phosphonovaleric acid on N-methyl-D-aspartic acid induced changes in extracellular concentration of dopamine and DOPAC in the rat neostriatum.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Extracellular Space; Kinetics; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Time Factors | 1992 |
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Proto-Oncogene Proteins c-fos; Signal Transduction | 1992 |
Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Bicuculline; Electric Stimulation; Kainic Acid; Kindling, Neurologic; Male; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission | 1992 |
L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Female; Glutamates; Glycine; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Pregnancy; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1992 |
Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-D-aspartate-produced facilitation of the nociceptive tail-flick reflex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Enzyme Activation; Guanylate Cyclase; Male; N-Methylaspartate; Nitric Oxide; Pain; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reflex | 1992 |
Low concentrations of N-methyl-D-aspartate inhibit the induction of long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Synapses | 1992 |
Retinogeniculate EPSPs recorded intracellularly in the ferret lateral geniculate nucleus in vitro: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials, Visual; Ferrets; Geniculate Bodies; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Visual Pathways | 1992 |
Evidence that non-NMDA receptors are involved in the excitatory pathway from the pedunculopontine region to nigrostriatal dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; Glutamine; Iontophoresis; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Pons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses | 1992 |
Serotonin1A facilitation of frog motoneuron responses to afferent stimuli and to N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; Animals; Electric Stimulation; Evoked Potentials; Glycine; In Vitro Techniques; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rana pipiens; Serotonin; Spinal Cord; Spinal Nerve Roots; Tetrahydronaphthalenes; Tetrodotoxin; Tropanes | 1992 |
Glutamate, NMDA and NMDA receptor antagonists: cardiovascular effects of intrathecal administration in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1992 |
The effect of visual experience on development of NMDA receptor synaptic transmission in kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Cats; Darkness; Evoked Potentials; Iontophoresis; Light; N-Methylaspartate; Photic Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Vision, Ocular; Visual Cortex; Visual Perception | 1992 |
Carbamazepine-induced neurotoxicity and its prevention by NMDA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Carbamazepine; Cells, Cultured; Cerebellum; Cytoplasmic Granules; N-Methylaspartate; N-Methylscopolamine; Nervous System Diseases; Ouabain; Parasympatholytics; Rats; Rats, Inbred Strains; Scopolamine Derivatives; Sodium-Potassium-Exchanging ATPase | 1992 |
Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Chromosome Deletion; Cloning, Molecular; Dizocilpine Maleate; DNA; Gene Library; Kynurenic Acid; Molecular Sequence Data; N-Methylaspartate; Oocytes; Piperazines; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate; Restriction Mapping; RNA Splicing; RNA, Messenger; Xenopus | 1992 |
In vivo modulation of excitatory amino acid receptors: microdialysis studies on N-methyl-D-aspartate-evoked striatal dopamine release and effects of antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cadmium; Chromatography, High Pressure Liquid; Corpus Striatum; Dextromethorphan; Dialysis; Dopamine; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Potassium; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
N-methyl-D-aspartate antagonists suppress the development of frog symmetric monocular optokynetic nystagmus observed after unilateral visual deprivation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraperitoneal; Magnetics; Microinjections; N-Methylaspartate; Nystagmus, Physiologic; Pipecolic Acids; Rana esculenta; Receptors, N-Methyl-D-Aspartate; Vision, Monocular | 1992 |
Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding Sites; Binding, Competitive; Estradiol; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Ovariectomy; Progesterone; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Regulation of nerve growth factor and nerve growth factor receptor production by NMDA in C6 glioma cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Blotting, Northern; Bucladesine; Cyclic AMP; Glioma; Kainic Acid; Molecular Sequence Data; N-Methylaspartate; Neoplasm Proteins; Nerve Growth Factors; Quisqualic Acid; Rats; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1992 |
Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Cats; Female; Hypothalamus, Middle; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Periaqueductal Gray; Quinoxalines; Rage; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
Physiological effects of chronic and acute application of N-methyl-D-aspartate and 5-amino-phosphonovaleric acid to the optic tectum of Rana pipiens frogs.
Topics: 2-Amino-5-phosphonovalerate; Animals; Delayed-Action Preparations; Dominance, Cerebral; Dose-Response Relationship, Drug; Models, Neurological; N-Methylaspartate; Polyvinyls; Rana pipiens; Retina; Superior Colliculi | 1992 |
Release of endogenous adenosine and its metabolites by the activation of NMDA receptors in the rat hippocampus in vivo.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Calcium; Hippocampus; Male; N-Methylaspartate; Perfusion; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Veratridine | 1992 |
The effect of hypoxia on neurotransmitter phenotype of forebrain cholinergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cell Hypoxia; Cells, Cultured; Choline O-Acetyltransferase; Embryo, Mammalian; Glutamates; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Growth Factors; Neurons; Phenotype; Prosencephalon; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Lateral hypothalamus and local stimulation induced postsynaptic responses in zona incerta neurons in an in vitro slice preparation of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Evoked Potentials; Hypothalamic Area, Lateral; In Vitro Techniques; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurons; Periaqueductal Gray; Piperazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 1992 |
Interaction between thyrotropin-releasing hormone (TRH) and NMDA-receptor-mediated responses in hypoglossal motoneurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Brain Stem; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Synapses; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1992 |
N-methyl-D-aspartate effects on the growth, morphology and cytoskeleton of individual neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Division; Cells, Cultured; Cytoplasmic Granules; Cytoskeleton; N-Methylaspartate; Neurites; Neurons; Rats; Time Factors | 1992 |
Dual-component miniature excitatory synaptic currents in rat hippocampal CA3 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials, Somatosensory; Hippocampus; Hypertonic Solutions; In Vitro Techniques; Kainic Acid; Kinetics; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1992 |
Participation of arginine vasopressin-mediated and adrenergic system-mediated mechanisms in the hypertension induced by intracerebroventricular administration of NMDA in freely moving rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine Vasopressin; Blood Pressure; Cerebral Ventricles; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; N-Methylaspartate; Naloxone; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains | 1992 |
NMDA receptor antagonists block cardiovascular responses to intrathecal administration of D-baclofen in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Blood Pressure; Injections, Intravenous; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thoracic Vertebrae | 1992 |
N-acetylaspartylglutamate acts as an agonist upon homomeric NMDA receptor (NMDAR1) expressed in Xenopus oocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cloning, Molecular; Dipeptides; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Oocytes; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Transcription, Genetic; Xenopus laevis | 1992 |
The competitive NMDA antagonist CGP40.116 enhances L-dopa response in MPTP-treated marmosets.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2-Amino-5-phosphonovalerate; Animals; Callithrix; Dose-Response Relationship, Drug; Drug Synergism; Levodopa; Motor Activity; N-Methylaspartate | 1992 |
N-methyl-D-aspartate receptor-independent long-term potentiation in area CA1 of rat hippocampus: input-specific induction and preclusion in a non-tetanized pathway.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Microscopy, Electron; N-Methylaspartate; Pyramidal Tracts; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors | 1992 |
Mossy fiber long-term potentiation shows specificity but no apparent cooperativity.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nerve Fibers; Pyramidal Tracts; Synapses; Time Factors | 1992 |
NMDA enhances the central depressant properties of ethanol in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Central Nervous System Depressants; Drug Synergism; Ethanol; GABA Antagonists; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Postural Balance | 1992 |
Stimulation of cultured cerebellar granule cells via glutamate receptors induces TRE- and CRE-binding activities mediated by common DNA-binding complexes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Blotting, Northern; Calcium; Cells, Cultured; Cerebellum; Cyclic AMP; DNA-Binding Proteins; Kainic Acid; Magnesium; Mice; Mice, Inbred ICR; Molecular Sequence Data; N-Methylaspartate; Protein Binding; Proto-Oncogene Proteins c-fos; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate | 1992 |
Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Epilepsy; Glutamine; Kainic Acid; Limbic System; Male; N-Methylaspartate; Neurotransmitter Agents; Pilocarpine; Pons; Rats; Rats, Wistar; Thalamus | 1992 |
Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Glycine; Hypothalamus; Kainic Acid; Magnesium; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
A voltage-clamp analysis of NMDA-induced responses on dopaminergic neurons of the rat substantia nigra zona compacta and ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dopamine; Electric Conductivity; Female; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Sodium; Substantia Nigra; Tegmentum Mesencephali; Tetrodotoxin | 1992 |
Effect of magnesium on calcium influx activated by glutamate and its agonists in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Nifedipine; Phencyclidine; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Verapamil | 1992 |
Niacinamide blocks 3-acetylpyridine toxicity of cerebellar granule cells in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Mazindol; N-Methylaspartate; Neurons; Niacinamide; Pyridines; Rats; Rats, Sprague-Dawley; Selegiline; Tetrahydrofolates | 1992 |
Effects of intrahippocampal injections of N-methyl-D-aspartate receptor antagonists and scopolamine on working and reference memory assessed in rats by a three-panel runway task.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Male; Memory; N-Methylaspartate; Pipecolic Acids; Piperazines; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1992 |
Bioisosteric replacement of the alpha-amino carboxylic acid functionality in 2-amino-5-phosphonopentanoic acid yields unique 3,4-diamino-3-cyclobutene-1,2-dione containing NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Carboxylic Acids; Male; Mice; N-Methylaspartate; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Structure-Activity Relationship | 1992 |
Hippocampal long-term potentiation in nucleus basalis magnocellularis-lesioned rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Electric Stimulation; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; N-Methylaspartate; Nerve Fibers; Olivary Nucleus; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques | 1992 |
The paradoxical effect of NMDA receptor stimulation on electrical activity of the sensorimotor cortex in freely behaving rats: analysis by combined EEG-intracerebral microdialysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Carbachol; Cerebrospinal Fluid; Dialysis; Electroencephalography; Electrophysiology; Hippocampus; Male; Motor Cortex; N-Methylaspartate; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1992 |
[Species differences in the action of concurrent NMDA receptor antagonists in mouse and rat hippocampal neurons].
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Hippocampus; Mice; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Species Specificity | 1992 |
Inhibitory effects of excitatory amino acids on pyramidal cells of the in vitro turtle medial cortex.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cerebral Cortex; Electric Stimulation; Electroencephalography; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Membrane Potentials; N-Methylaspartate; Piperazines; Pyramidal Tracts; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin; Turtles | 1992 |
N-methyl-D-aspartate (NMDA) and non-NMDA (metabotropic) type glutamate receptors modulate the membrane potential of the Schwann cell of the squid giant nerve fibre.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Axons; Decapodiformes; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schwann Cells | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. II. Evidence for functional cooperation and for coexistence on the same axon terminal.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dizocilpine Maleate; Drug Interactions; Hippocampus; Ibotenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Presynaptic modulation of amino acid release from synaptosomes.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Male; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptosomes | 1992 |
N-methyl-D-aspartate receptor antagonism alters substance P and met5-enkephalin biosynthesis in neurons of the rat striatum.
Topics: Animals; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Male; N-Methylaspartate; Neurons; Piperazines; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P; Tachykinins; Valine | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Glutamatergic regulation of histamine release from rat hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glutamates; Glutamic Acid; Histamine Release; Hypothalamus, Anterior; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1992 |
Evidence for nitric oxide synthase inhibitor-sensitive and insensitive hippocampal synaptic potentiation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Conditioning, Psychological; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Rats, Inbred F344; Synapses | 1992 |
Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Culture Techniques; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Pharmacological profile of novel cyclic analogs of 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Electroshock; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship | 1992 |
N-methyl-D-aspartate unilaterally injected into the dorsal striatum of rats produces contralateral circling: antagonism by 2-amino-7-phosphonoheptanoic acid and cis-flupenthixol.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Corpus Striatum; Flupenthixol; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Rotation | 1992 |
NMDA receptor antagonists protect against seizures and wet-dog shakes induced by 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amino Acids; Animals; Behavior, Animal; Male; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures | 1992 |
N-methyl-D-aspartate and vasopressin activate distinct voltage-dependent inward currents in facial motoneurones.
Topics: Animals; Arginine Vasopressin; Brain Stem; Dizocilpine Maleate; Electric Conductivity; Evoked Potentials; Facial Nerve; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Valine | 1992 |
Studies of the role of the N-methyl-D-aspartate (NMDA) receptor in the hypothalamic control of prolactin secretion.
Topics: Animals; Hypothalamus; Male; N-Methylaspartate; Prolactin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-D-aspartate receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Learning; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Swimming | 1992 |
Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Corpus Striatum; Dopamine; Electrophysiology; Injections; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1992 |
Endogenous activation of NMDA and non-NMDA glutamate receptors on respiratory neurones in cat medulla.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Decerebrate State; Iontophoresis; Medulla Oblongata; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiratory Center | 1991 |
Postsynaptic factors control the duration of synaptic enhancement in area CA1 of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Electric Stimulation; Electrophysiology; Hippocampus; Kinetics; N-Methylaspartate; Neurotransmitter Agents; Rats; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Synapses | 1991 |
NMDA receptor agonists selectively block N-type calcium channels in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Aspartic Acid; Calcium; Calcium Channels; Glutamates; Hippocampus; Kynurenic Acid; Mollusk Venoms; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1991 |
GABAA and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kainic Acid; Male; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
Anticonvulsant and behavioral effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Ataxia; Behavior, Animal; Carbamazepine; Dizocilpine Maleate; Female; Kindling, Neurologic; Motor Activity; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Initiation of epileptiform activity by excitatory amino acid receptors in the disinhibited rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cerebral Cortex; Electricity; Epilepsy; Female; Male; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Cell damage associated with changing the medium of mesencephalic cultures in serum-free medium is mediated via N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Buffers; Cells, Cultured; Culture Media; Dizocilpine Maleate; Glutamates; Glutamic Acid; Mesencephalon; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1991 |
N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cells, Cultured; Electrophysiology; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Retinal Ganglion Cells | 1991 |
Electrogenic uptake contributes a major component of the depolarizing action of L-glutamate in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport, Active; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; In Vitro Techniques; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Synaptic Transmission | 1991 |
L-phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes.
Topics: 2-Amino-5-phosphonovalerate; Alzheimer Disease; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glycine; Kainic Acid; N-Methylaspartate; Phosphoserine; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Ipsilateral but not contralateral blockade of excitatory amino acid receptors in the caudal ventrolateral medulla inhibits aortic baroreceptor reflex in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aorta; Blood Pressure; Dizocilpine Maleate; Electric Stimulation; Glutamates; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Muscimol; N-Methylaspartate; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Reflex; Synaptic Transmission | 1991 |
Electrophysiological evidence for the presence of NMDA receptors in the guinea pig cochlea.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Animals; Auditory Pathways; Cochlea; Cochlear Microphonic Potentials; Electrophysiology; Female; Glycine; Guinea Pigs; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate | 1991 |
Inhibition of rabies virus infection in cultured rat cortical neurons by an N-methyl-D-aspartate noncompetitive antagonist, MK-801.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Dizocilpine Maleate; N-Methylaspartate; Neurons; Rabies; Rabies virus; Rats; Virus Replication | 1991 |
Interaction of ethanol and L-glutamate in the guinea pig ileum myenteric plexus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Electric Stimulation; Ethanol; Female; Glutamates; Glutamic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Magnesium; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serotonin; Tetrodotoxin | 1991 |
Disruption of retinogeniculate afferent segregation by antagonists to NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Dizocilpine Maleate; Ferrets; Geniculate Bodies; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retinal Ganglion Cells; Visual Pathways | 1991 |
N-methyl-D-aspartate receptor participates in neuronal transmission of photic information through the retinohypothalamic tract.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arylamine N-Acetyltransferase; Hypothalamus; Light; Male; Melatonin; N-Methylaspartate; Neurons; Phencyclidine; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Retina; Suprachiasmatic Nucleus; Synaptic Transmission | 1991 |
Effects of excitatory amino acids and their antagonists on the light response of luminosity and color-opponent horizontal cells in the turtle (Pseudemys scripta elegans) retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Color Perception; Dizocilpine Maleate; Electrophysiology; Kainic Acid; Light; N-Methylaspartate; Photic Stimulation; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles | 1991 |
Chronic effects of NMDA and APV on tectal output in Xenopus laevis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Vision, Binocular; Xenopus laevis | 1991 |
Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glutamates; Glutamic Acid; Glutamine; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Role of excitatory amino acids in mediating burst discharge of red nucleus neurons in the in vitro turtle brain stem-cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain Stem; Calcium; Cerebellum; Electric Stimulation; In Vitro Techniques; Iontophoresis; Magnesium; Microelectrodes; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Quisqualic Acid; Red Nucleus; Spinal Cord; Turtles | 1991 |
Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Glutamates; Glutamic Acid; Macaca fascicularis; N-Methylaspartate; Neurons; Quisqualic Acid; Spinothalamic Tracts | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
Effects of MK-801, a non-competitive NMDA antagonist, on linguopharyngeal events in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Ataxia; Behavior, Animal; Dizocilpine Maleate; Female; Motor Activity; N-Methylaspartate; Nystagmus, Physiologic; Pharynx; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Tongue | 1991 |
Regulation of CCK release in cerebral cortex by N-methyl-D-aspartate receptors: sensitivity to APV, MK-801, kynurenate, magnesium and zinc ions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Dizocilpine Maleate; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Potassium; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Sincalide; Zinc | 1991 |
Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; Alanine Transaminase; Animals; Calcium; Dizocilpine Maleate; Glutamates; Glutamic Acid; HIV Envelope Protein gp120; N-Methylaspartate; Neurotoxins; Osmolar Concentration; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells | 1991 |
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Diseases; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Regional alterations in brain amino acids after administration of the N-methyl-D-aspartate receptor antagonists MK-801 and CGP 39551 in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Brain Chemistry; Brain Mapping; Dizocilpine Maleate; Female; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Actions of noradrenaline on neocortical neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Conductivity; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Isoproterenol; Male; N-Methylaspartate; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Somatosensory Cortex | 1991 |
N-methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channels; Cyclic AMP; Egtazic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Excitatory amino acid modulation of lordosis in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Estradiol; Female; Hypothalamus, Middle; Infusions, Parenteral; N-Methylaspartate; Posture; Preoptic Area; Progesterone; Rats; Rats, Inbred Strains; Reference Values; Sexual Behavior, Animal; Vocalization, Animal | 1991 |
[Effect of N-methyl-D-aspartate on the spontaneous activity generated by isolated spinal cord of 16 to 20-day-old chick embryos].
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Chick Embryo; In Vitro Techniques; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots | 1991 |
Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Denervation; Evoked Potentials; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses | 1991 |
Chronic application of NMDA decreases the NMDA sensitivity of the evoked tectal potential in the frog.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; N-Methylaspartate; Optic Nerve; Quisqualic Acid; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1991 |
Dopamine agonists potentiate antiakinetic effects of competitive NMDA-antagonists in monoamine-depleted mice.
Topics: 2-Amino-5-phosphonovalerate; alpha-Methyltyrosine; Animals; Binding, Competitive; Caudate Nucleus; Dopamine Agents; Drug Synergism; Dyskinesia, Drug-Induced; Indoles; Male; Methyltyrosines; Mice; Motor Activity; N-Methylaspartate; Piperazines; Putamen; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reserpine | 1991 |
Retinogeniculate transmission by NMDA and non-NMDA receptors in the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Geniculate Bodies; Glutamates; Glutamic Acid; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Synaptic Transmission | 1991 |
The competitive NMDA antagonist AP5, but not the non-competitive antagonist MK801, induces a delay-related impairment in spatial working memory in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Ventricles; Choice Behavior; Dizocilpine Maleate; Injections, Intraventricular; Male; Memory; N-Methylaspartate; Rats; Rats, Inbred Strains; Reference Values; Space Perception | 1991 |
Uneven distribution of excitatory amino acid receptors on ventral horn neurones of newborn rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Dendrites; Dose-Response Relationship, Drug; Glutamates; Kainic Acid; Membrane Potentials; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord | 1991 |
Interactions of glutamate receptor agonists coupled to changes in intracellular Ca2+ in rat cerebellar granule cells in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Fura-2; Glutamates; Kainic Acid; Kinetics; Magnesium; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium; Spectrometry, Fluorescence | 1991 |
N-methyl-D-aspartate increases cytoplasmic free calcium in mouse hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Chlorides; Cytoplasm; Dizocilpine Maleate; Hippocampus; Magnesium Chloride; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Zinc; Zinc Compounds | 1991 |
Pharmacological evidence that NMDA receptors contribute to mono- and di-synaptic potentials in slices of mouse olfactory cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Mice; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synapses | 1991 |
Kainate and NMDA toxicity for cultured developing and adult rat spiral ganglion neurons: further evidence for a glutamatergic excitatory neurotransmission at the inner hair cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cochlea; Ganglia; Glutamates; Glutamic Acid; Hair Cells, Auditory, Inner; Immunohistochemistry; In Vitro Techniques; Indicators and Reagents; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Organ of Corti; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Transmission | 1991 |
Ethanol inhibits the N-methyl-D-aspartate (NMDA)-induced attenuation of the NMDA-evoked noradrenaline release in the rat brain cortex: interaction with NMDA-induced desensitization.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Dizocilpine Maleate; Ethanol; In Vitro Techniques; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tritium | 1991 |
Mediation of visual responses in the nucleus of the optic tract in cats and rats by excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Evoked Potentials; Evoked Potentials, Visual; Female; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Optic Chiasm; Photic Stimulation; Quinoxalines; Quisqualic Acid; Rats; Receptors, Neurotransmitter | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
Tonically rhythmic neurons within a cardiorespiratory region of the nucleus tractus solitarii of the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cardiovascular System; Cobalt; Dizocilpine Maleate; gamma-Aminobutyric Acid; Kynurenine; Male; Medulla Oblongata; Membrane Potentials; N-Methylaspartate; Neurons; Neurons, Afferent; Pressoreceptors; Quisqualic Acid; Rats; Rats, Inbred Strains; Respiratory System; Synapses | 1991 |
Receptor sub-types involved in responses of Purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cerebellum; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Excitatory amino acids evoke taurine release from cerebral cortex slices from adult and developing mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotoxins; Potassium; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Secretory Rate; Stimulation, Chemical; Taurine | 1991 |
NMDA and non-NMDA receptors mediate visual responses of neurons in the cat's lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Time Factors; Visual Perception | 1991 |
GABAB receptor stimulation by baclofen and taurine enhances excitatory amino acid induced phosphatidylinositol turnover in neonatal rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Calcium; Cerebellum; gamma-Aminobutyric Acid; N-Methylaspartate; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Receptors, GABA-A; Taurine | 1991 |
N-methyl-D-aspartate and aspartate raise the cytosolic free calcium concentration by acting upon receptors transiently expressed on immature cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebellum; Cytosol; Gallopamil; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Purkinje Cells; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
Evidence that activation of N-methyl-D-aspartate (NMDA) and non-NMDA receptors within the nucleus tractus solitarii triggers swallowing.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Facial Nerve; Glutamates; Glutamic Acid; Medulla Oblongata; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
N-methyl-D-aspartate receptor-mediated spontaneous activity in cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium Channels; Cells, Cultured; Cerebellum; Cobalt; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kynurenic Acid; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1991 |
An arthropod NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Astacoidea; Cesium; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Immunoenzyme Techniques; Interneurons; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1991 |
Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy.
Topics: Animals; Catalepsy; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haloperidol; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1991 |
Participation of excitatory amino acid receptors in the slow excitatory synaptic transmission in rat spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Neurotoxicity of quinolinic acid and its derivatives in hypoxic rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dose-Response Relationship, Drug; Hippocampus; Hypoxia; In Vitro Techniques; Magnesium; Male; Molecular Structure; N-Methylaspartate; Neurotoxins; Picolinic Acids; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1991 |
Sensitivity of rubrospinal neurons to excitatory amino acids in the rat red nucleus in vivo.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Aspartic Acid; Cats; Cerebellum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Iontophoresis; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Red Nucleus; Species Specificity | 1991 |
Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Serotonin; Synapses; Synaptic Transmission; Time Factors | 1991 |
Stimulation of noradrenaline release in the cerebral cortex via presynaptic N-methyl-D-aspartate (NMDA) receptors and their pharmacological characterization.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1991 |
Voltage-gated and chemically gated ionic channels in the cultured cochlear ganglion neurone of the chick.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium Channels; Cell Membrane Permeability; Chick Embryo; Cochlear Nerve; Ganglia; Glutamates; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Potassium Channels; Sodium Channels | 1990 |
Miniature excitatory synaptic currents in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Aspartic Acid; Calcium Channel Blockers; Cells, Cultured; Dipeptides; Electrophysiology; Fetus; Hippocampus; Kinetics; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Synapses; Tetrodotoxin | 1990 |
Effects of urethane and ketamine on substance P- and excitatory amino acid-induced behavior in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Injections, Spinal; Isomerism; Kainic Acid; Ketamine; Male; Mice; N-Methylaspartate; Quisqualic Acid; Substance P; Urethane | 1990 |
Glutamate, kainate and quisqualate enhance GABA-dependent chloride uptake in cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Cerebral Cortex; Chloride Channels; Chlorides; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, GABA-A | 1990 |
The effects of substance P analogues on the scratching, biting and licking response induced by intrathecal injection of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Behavior, Animal; Injections, Spinal; Mice; Mice, Inbred Strains; N-Methylaspartate; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Substance P | 1990 |
Calcium, network activity, and the role of NMDA channels in synaptic plasticity in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Electric Stimulation; Evoked Potentials; Fetus; Ion Channels; Mice; N-Methylaspartate; Neuronal Plasticity; Neurons; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1991 |
Proteolytic enzymes do not destroy the N-methyl-D-aspartate (NMDA) sensitivity of acutely isolated hippocampal CA1 and CA3 neurons from postnatal rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Cell Separation; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; Glycine; Hippocampus; Ion Channels; Magnesium; N-Methylaspartate; Neurons; Peptide Hydrolases; Rats | 1990 |
Glutamate-induced increases in intracellular Ca2+ in cultured frog tectal cells mediated by direct activation of NMDA receptor channels.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Intracellular Membranes; Ion Channels; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Superior Colliculi | 1991 |
Nonstationary fluctuation analysis and direct resolution of single channel currents at postsynaptic sites.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Evoked Potentials; Hippocampus; Ion Channels; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Synapses | 1991 |
Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Nociceptors; Pain; Peptide Fragments; Reaction Time; Substance P; Urethane | 1991 |
Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Carbamazepine; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Female; Ion Channels; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Phenytoin; Pregnancy; Spinal Cord | 1990 |
Behavioral sensitization to kainic acid and quisqualic acid in mice: comparison to NMDA and substance P responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Capsaicin; Concanavalin A; Drug Tolerance; GABA Antagonists; Glycine; Injections, Spinal; Kainic Acid; Mice; N-Methylaspartate; Quisqualic Acid; Spinal Cord; Substance P | 1991 |
Glutamate-activated channels in adult rat ventral spinal cord cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Membrane; Chick Embryo; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Spinal Cord | 1991 |
Glutamate receptor agonist-induced inward currents in spinal dorsal horn neurons dissociated from the adult rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Ion Channels; Kainic Acid; N-Methylaspartate; Nerve Fibers; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord | 1991 |
N-methyl-D-aspartate increases the excitability of nigrostriatal dopamine terminals.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Binding, Competitive; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Nerve Fibers; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Acetylcholine release from the rabbit retina mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Convulsants; Dizocilpine Maleate; Glycine; In Vitro Techniques; Light; Magnesium; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1991 |
NMDA antagonists attenuate hypertension induced by carotid clamping in the rostral ventrolateral medulla of rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Arterial Occlusive Diseases; Blood Pressure; Carotid Arteries; Carotid Artery Diseases; Cerebral Ventricles; Hypertension; Injections, Intraventricular; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Pain; Phencyclidine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Vagotomy | 1991 |
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Female; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Social Isolation; Vocalization, Animal | 1990 |
Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Computer Simulation; Ibotenic Acid; Kainic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship | 1990 |
Selective depression of the segmental polysynaptic reflex by phencyclidine and its analogs in the rat in vitro: interaction with N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Haloperidol; In Vitro Techniques; Magnesium; Male; Methiothepin; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Spinal Cord | 1990 |
Quisqualate activates N-methyl-D-aspartate receptor channels in hippocampal neurons maintained in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Electric Stimulation; Glycine; Hippocampus; Indoles; Ion Channel Gating; N-Methylaspartate; Neural Conduction; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Competitive and noncompetitive N-methyl-D-aspartate antagonists modify hypoxia-induced membrane potential changes and protect rat hippocampal slices from functional failure: a quantitative comparison.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Cell Hypoxia; Cell Survival; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains | 1990 |
N-methyl-D-aspartate receptors contribute to excitatory postsynaptic potentials of cat lateral geniculate neurons recorded in thalamic slices.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Aspartic Acid; Axons; Calcium; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Thalamus; Visual Pathways | 1990 |
Evidence for the presence of N-methyl-D-aspartate receptors in the ventral tegmental area of the rat: an electrophysiological in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tegmentum Mesencephali | 1990 |
Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Aspartic Acid; Cells, Cultured; Glycine; Hippocampus; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Osmolar Concentration; Piperazines | 1990 |
Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Aspartic Acid; Conditioning, Psychological; Fear; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex, Startle | 1990 |
Acetylcholine potentiates responses to N-methyl-D-aspartate in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebellum; Electric Conductivity; Female; Glycine; Guinea Pigs; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Phencyclidine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1990 |
Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1990 |
Effects of antagonists on N-methyl-D-aspartate response in acutely isolated nucleus tractus solitarii neurons of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Medulla Oblongata; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
In vivo evidence for an inhibitory glutamatergic control of serotonin release in the cat caudate nucleus: involvement of GABA neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Riluzole; Serotonin; Spinal Cord; Synaptic Transmission; Tetrodotoxin; Thiazoles | 1990 |
Spinal antinociceptive effects of excitatory amino acid antagonists: quisqualate modulates the action of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesics; Animals; Aspartic Acid; Dipeptides; Electric Stimulation; Glutamine; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Vocalization, Animal | 1990 |
Veratridine and other depolarizing agents counteract the inhibitory effect of Mg2+ ions on N-methyl-D-aspartate (NMDA)-induced noradrenaline release in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amifampridine; Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Hydrogen; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Veratridine; Veratrine | 1990 |
N-methyl-D-aspartate stimulates the release of dopamine from rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dopamine; Hippocampus; Interneurons; Male; Memory; N-Methylaspartate; Neuronal Plasticity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Tetrodotoxin | 1990 |
Differentiation of the active site of minaprine from that of phencyclidine in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Binding Sites; Hippocampus; Ketamine; Male; Membranes; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Potassium Channels; Pyridazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
APV-sensitive dorsal root afferent transmission to neonate rat sympathetic preganglionic neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Animals, Newborn; Electrophysiology; Ganglia, Sympathetic; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats; Spinal Cord; Synaptic Transmission | 1990 |
Excitatory synaptic currents in Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Conductivity; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Purkinje Cells; Quinoxalines; Rats; Synapses | 1990 |
Effects of NMDA antagonists on developmental plasticity in kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics; Animals; Animals, Newborn; Cats; Cerebral Cortex; Dizocilpine Maleate; Injections; Ketamine; N-Methylaspartate; Neuronal Plasticity; Visual Cortex | 1990 |
Synaptic transmission in human neocortex removed for treatment of intractable epilepsy in children.
Topics: 2-Amino-5-phosphonovalerate; Adolescent; Bicuculline; Child; Child, Preschool; Epilepsy; Female; GABA Antagonists; Humans; Infant; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Psychosurgery; Pyramidal Tracts; Spasms, Infantile; Synapses; Synaptic Transmission | 1990 |
A 3,4-dihydroxyphenylalanine oxidation product is a non-N-methyl-D-aspartate glutamatergic agonist in rat cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebral Cortex; Dihydroxyphenylalanine; Evoked Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rats | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Kynurenic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Degeneration; Neurons; Oocytes; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Taurine; Xenopus | 1990 |
Phencyclidine and related compounds evoked [3H]dopamine release from rat mesencephalic cell cultures by a mechanism independent of the phencyclidine receptor, sigma binding site, or dopamine uptake site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Binding Sites; Cells, Cultured; Dioxolanes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Guanidines; Mesencephalon; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Phencyclidine; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Sigma Factor; Tritium | 1990 |
Intrathecal N-methyl-D-aspartate induces hyperexcitability in rat dorsal horn convergent neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Injections, Spinal; Male; N-Methylaspartate; Neural Inhibition; Neurons; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Spinal Cord | 1990 |
Neurotoxic effects of excitatory amino acids in the mouse spinal cord: quisqualate and kainate but not N-methyl-D-aspartate induce permanent neural damage.
Topics: 2-Amino-5-phosphonovalerate; Aggression; Animals; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methylaspartate; Neurons; Neurotoxins; Pain; Paralysis; Quisqualic Acid; Spinal Cord | 1990 |
Evidence for involvement of N-methyl-D-aspartate receptor in tonic inhibitory control of dopaminergic transmission in rat medial frontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Cerebral Cortex; Dopamine; Glutamine; Infusions, Parenteral; Isomerism; Male; Methyltyrosines; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1990 |
A topological model of the NMDA-glycine receptor model.
Topics: 2-Amino-5-phosphonovalerate; Glutamates; Glutamic Acid; Glycine; Models, Molecular; N-Methylaspartate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Cytotoxic effect of glutamate and its agonists on mouse hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Dipeptides; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Pregnancy; Quinolinic Acid; Quinolinic Acids | 1990 |
NMDA antagonists prevent hypothermic injury and death of mammalian spinal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Dizocilpine Maleate; Female; Freezing; Hypothermia, Induced; Ketamine; Mice; N-Methylaspartate; Neurons; Pregnancy; Spinal Cord Injuries | 1990 |
Spinal neuronal pathology associated with continuous intrathecal infusion of N-methyl-D-aspartate in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glycine; Infusions, Parenteral; Magnesium Sulfate; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord | 1990 |
Rhythmic bursting patterns induced in neurons of the rat nucleus tractus solitarii, in vitro, in response to N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Glutamates; Glutamic Acid; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
Protection by ethanol of cortical neurons from N-methyl-D-aspartate-induced neurotoxicity is associated with blocking calcium influx.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cerebral Cortex; Ethanol; Female; Ketamine; L-Lactate Dehydrogenase; N-Methylaspartate; Nervous System Diseases; Neurons; Pregnancy; Rats | 1990 |
Responses to excitatory amino acids of Purkinje cells' and neurones of the deep nuclei in cerebellar slice cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Animals, Newborn; Cells, Cultured; Cerebellar Nuclei; Cerebellum; N-Methylaspartate; Neurons; Purkinje Cells; Quinoxalines; Rats | 1990 |
N-methyl-D-aspartate, kainate and quisqualate release endogenous adenosine from rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Animals; Calcium; Cerebral Cortex; Dipeptides; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraventricular; Kynurenic Acid; Learning; Male; Mice; N-Methylaspartate; Piperazines; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine | 1990 |
Ethanol inhibits NMDA-stimulated neurite growth by sensory neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Chick Embryo; Ethanol; Ganglia, Spinal; Glycine; Kynurenic Acid; Magnesium; N-Methylaspartate; Neurites; Neurons, Afferent | 1990 |
Modulation of neuronal activity of locus coeruleus in rats induced by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Electrophysiology; Glutamates; Locus Coeruleus; Male; N-Methylaspartate; Neurons; Quinolinic Acids; Rats; Rats, Inbred Strains | 1990 |
N-methyl-D-aspartate receptors of ganglion cells in rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Valine | 1990 |
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices.
Topics: Animals; Aspartic Acid; Calcineurin; Calmodulin-Binding Proteins; Colforsin; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Activation; N-Methylaspartate; Nerve Tissue Proteins; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphothreonine; Protein Kinases; Protein Phosphatase 1; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
A unified approach to systematic isosteric substitution for acidic groups and application to NMDA antagonists related to 2-amino-7-phosphonoheptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Models, Molecular; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Effect of NMDA and 2-amino-7-phosphonoheptanoate focal injection into the ventrolateral thalamic nucleus on the high pressure neurological syndrome in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Central Nervous System Diseases; High Pressure Neurological Syndrome; Male; Microinjections; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamic Nuclei | 1990 |
Ethanol inhibits N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat cortical slices.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Culture Techniques; Ethanol; Glycine; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Valine | 1990 |
Differential modulation of the associated glycine recognition site by competitive N-methyl-D-aspartate receptor antagonists.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Glycine; Male; N-Methylaspartate; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electroencephalography; Epilepsy; Female; Injections, Intraventricular; Male; N-Methylaspartate; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
The effects of potassium-induced depolarization, glutamate receptor antagonists and N-methyl-D-aspartate on neuronal survival in cultured neocortex explants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cell Survival; Cerebral Cortex; Culture Techniques; Electrophysiology; Glutamates; N-Methylaspartate; Neurons; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1990 |
Efflux of 45calcium from cultured primary astrocytes: effects of glutamate receptor agonists and antagonists.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Calcium Radioisotopes; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Valine | 1990 |
Dibenzocycloalkenimine (MK-801) stimulates phosphoinositide hydrolysis in rat cerebral cortical slices).
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atropine; Cerebral Cortex; Dizocilpine Maleate; Hydrolysis; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Phencyclidine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Zinc | 1990 |
Stereospecificity of N-MDA-induced functional deficits.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Hippocampus; Learning; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred F344; Stereoisomerism | 1990 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1986 |
A study of amino acid-activated currents recorded from frog motoneurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neural Conduction; Oxadiazoles; Quisqualic Acid; Rana temporaria; Valine | 1987 |
Stimulation of the N-methyl-D-aspartate receptor promotes the biochemical differentiation of cerebellar granule neurons and not astrocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Cell Differentiation; Cells, Cultured; Cerebellum; Glutaminase; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA; Valine | 1989 |
NMDA receptor antagonists can enhance or impair learning performance in animals.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gerbillinae; Male; Memory; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Antagonism of monosynaptic excitations in the mouse olfactory cortex slice by 6,7-dinitroquinoxaline-2,3-dione.
Topics: Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Male; Mice; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Reflex, Monosynaptic; Synapses; Synaptic Transmission; Valine | 1989 |
The specific NMDA receptor antagonist AP-7 attenuates focal ischemic brain injury.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Ischemic Attack, Transient; Kinetics; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Catalepsy; Globus Pallidus; Male; N-Methylaspartate; Nervous System Diseases; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Substantia Nigra; Syndrome | 1989 |
The N-methyl-D-aspartate antagonists aminophosphonovaleric acid and MK-801 reduce anoxic damage to dentate granule and CA1 pyramidal cells in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Male; N-Methylaspartate; Neurotoxins; Pyramidal Tracts; Rats; Rats, Inbred Strains; Valine | 1989 |
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine | 1989 |
Long-lasting physiological effects of bath applied N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Spermine; Time Factors; Valine | 1989 |
Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Oxadiazoles; Phenazocine; Potassium; Putamen; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
A local circuit neocortical synapse that operates via both NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dipeptides; Electric Stimulation; Female; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neural Conduction; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1989 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Evidence for excitatory amino acid transmission between mesencephalic nucleus of V afferents and jaw-closer motoneurons in the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Guinea Pigs; Kynurenic Acid; Male; Masseter Muscle; Mesencephalon; Motor Neurons; N-Methylaspartate; Neurotransmitter Agents; Synapses; Synaptic Transmission; Trigeminal Nuclei; Valine | 1989 |
Cytosolic free calcium and NAD/NADH redox state in the cat cortex during in vivo activation of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cats; Cerebral Cortex; Cytosol; Fluorescent Dyes; In Vitro Techniques; Male; N-Methylaspartate; NAD; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Solubilization of quisqualate-sensitive [3H]glutamate binding activity from rat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Octoxynol; Oxadiazoles; Polyethylene Glycols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Solubility | 1989 |
EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Excitatory amino acid receptors in rat locus coeruleus. An extracellular in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Locus Coeruleus; Magnesium; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1989 |
A slow NMDA-mediated synaptic potential underlies seizures originating from midbrain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; In Vitro Techniques; Inferior Colliculi; N-Methylaspartate; Picrotoxin; Rats; Seizures; Valine | 1989 |
Visual responses in adult cat visual cortex depend on N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cats; Electric Conductivity; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Perception | 1989 |
[Analysis of the effect of quisqualate, N-methyl-D- aspartate and several blockers of amino acid receptors on synaptic transmission in the ampullae of Lorenzini].
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Electric Fish; Evoked Potentials; Magnesium; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sensory Receptor Cells; Skates, Fish; Synapses; Synaptic Transmission; Valine | 1989 |
Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1989 |
Glycine potentiates NMDA responses in rat hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glycine; Hippocampus; Humans; N-Methylaspartate; Rats; Valine | 1989 |
NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1989 |
Effects of excitant amino acids on acoustic responses of inferior colliculus neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Inferior Colliculi; N-Methylaspartate; Parasympathomimetics; Rats; Rats, Inbred Strains; Valine | 1989 |
A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Female; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1989 |
Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Electrophysiology; Glutamates; Glycine; Hippocampus; Histocytochemistry; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
Coexistence of NMDA and non-NMDA receptors on turtle horizontal cells revealed using isolated retina preparations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Visual; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles; Valine | 1989 |
Ethanol inhibits NMDA-induced increases in free intracellular Ca2+ in dissociated brain cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Brain; Calcium; Cell Separation; Ethanol; Fluorescent Dyes; In Vitro Techniques; Magnesium; N-Methylaspartate; Rats; Rats, Inbred Strains | 1989 |
Penicillin-induced bursting in motoneurones of the frog spinal cord. Elimination by NMDA antagonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Penicillins; Rana ridibunda; Spinal Cord | 1989 |
Excitatory amino acid receptor-mediated activation of solitarial deglutitive loci.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Deglutition; Dipeptides; Esophagus; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Pharynx; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Different modulation of the binding to two phencyclidine (PCP) receptor subtypes: effects of N-methyl-D-aspartate agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Glutamates; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1989 |
Different classes of glutamate receptors mediate distinct behaviors in a single brainstem nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Brain Stem; Electric Fish; Electric Organ; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Algorithms; Animals; Aspartic Acid; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Least-Squares Analysis; Magnesium; Microelectrodes; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1989 |
N-methyl-D-aspartate antagonists prevent interaction of binocular maps in Xenopus tectum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Functional Laterality; N-Methylaspartate; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Regression Analysis; Superior Colliculi; Visual Fields; Xenopus | 1989 |
Pharmacology of calcium-induced long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Atropine; Calcium; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Propranolol; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Respiratory effects of N-methyl-D-aspartate on the ventrolateral medullary surface.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Blood Pressure; Carbon Dioxide; Carotid Sinus; Cats; Female; Male; Medulla Oblongata; N-Methylaspartate; Phrenic Nerve; Respiration; Tidal Volume; Vagotomy | 1989 |
Quisqualate and N-methyl-D-aspartate synergistically excite cerebellar Purkinje cells as a long-term effect.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Female; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats | 1989 |
Bicuculline- and phaclofen-sensitive components of N-methyl-D-aspartate-induced hyperpolarizations in rat dorsolateral septal nucleus neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Baclofen; Bicuculline; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Septal Nuclei; Tetrodotoxin | 1989 |
Excitatory amino acids mediate responses elicited in vitro by stimulation of cortical afferents to reticularis thalami neurons of the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains; Thalamus | 1989 |
Traumatic neuronal injury in vitro is attenuated by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Dextrorphan; Mice; Morphinans; N-Methylaspartate; Nerve Tissue; Neuroglia; Neurons; Stress, Mechanical | 1989 |
NMDA receptor antagonists disrupt the retinotectal topographic map.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anura; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Superior Colliculi | 1989 |
N-methyl-D-aspartate induces recurrent synchronized burst activity in immature hippocampal CA3 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Tetrodotoxin | 1989 |
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
Long-term development of selective neuronal loss and the mechanism of protection by 2-amino-7-phosphonoheptanoate in a rat model of incomplete forebrain ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cell Survival; Cerebrovascular Circulation; Hippocampus; Ischemic Attack, Transient; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Inhibition of aminophylline-induced convulsions in mice by antiepileptic drugs and other agents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminophylline; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Female; Mice; N-Methylaspartate; Phenobarbital; Seizures; Synaptic Transmission; Valproic Acid | 1987 |
DL-2-amino-5-phosphonopentanoic acid, a specific N-methyl-D-aspartic acid receptor antagonist, suppresses pulsatile LH release in the rat.
Topics: Animals; Aspartic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cortical Spreading Depression; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Excitatory amino acids: role in morphine excitation in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; Motor Activity; N-Methylaspartate; Oxadiazoles; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Muscle relaxant action of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Spasticity; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
Mg2+ reduces N-methyl-D-aspartate neurotoxicity in embryonic chick neural retina in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Animals; Aspartic Acid; Chick Embryo; In Vitro Techniques; Magnesium; N-Methylaspartate; Retina; Valine | 1985 |
Effect of excitatory amino acids and analogues on [3H]acetylcholine release from amacrine cells of the rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cholinergic Fibers; Electroretinography; N-Methylaspartate; Neurons; Pipecolic Acids; Rabbits; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Valine | 1985 |
Synaptic transmission at N-methyl-D-aspartate receptors in the proximal retina of the mudpuppy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; In Vitro Techniques; N-Methylaspartate; Necturus; Receptors, Amino Acid; Receptors, Cell Surface; Retina; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Valine | 1985 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
Action of excitatory amino acids and their antagonists on hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; Iontophoresis; Manganese; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Tetrodotoxin; Valine | 1985 |
Evidence for an excitatory amino acid as the transmitter of the auditory nerve in the in vitro mouse cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials; Female; Kainic Acid; Male; Mice; Mice, Inbred C3H; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Neurotransmitter; Valine; Vestibulocochlear Nerve | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
A comparison of the effects of quinolinate and N-methyl-aspartate on neurons in rat piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Iontophoresis; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Rats; Valine | 1986 |
Ca2+-dependent depolarization and burst firing of rat CA1 pyramidal neurones induced by N-methyl-D-aspartic acid and quinolinic acid: antagonism by 2-amino-5-phosphonovaleric and kynurenic acids.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium; Convulsants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Valine | 1986 |
(+/-)-cis-2,3-Piperidine dicarboxylic acid is a partial N-methyl-D-aspartate agonist in the in vitro rat cerebellar cGMP model.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Quantitative studies of N-methyl-D-aspartate, 2-amino-5-phosphonovalerate and cis-2,3-piperidine dicarboxylate interactions on the neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electrophysiology; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Spinal Cord; Valine | 1986 |
Activity of beta-kainic acid on neocortical neurons in vivo and hippocampal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Hippocampus; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Receptors, Neurotransmitter; Valine | 1986 |
2-Amino-5-phosphonovalerate and Co2+ selectively block depolarization and burst firing of rat hippocampal CA1 pyramidal neurones by N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cobalt; Evoked Potentials; Hippocampus; Iontophoresis; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quisqualic Acid; Rats; Tetrodotoxin; Valine | 1986 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Catalepsy; Columbidae; Dose-Response Relationship, Drug; Injections, Intraventricular; N-Methylaspartate; Phencyclidine; Stereotyped Behavior; Valine | 1986 |
The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Brain; Cats; Cell Membrane; Interneurons; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Neurons; Piperazines; Rats; Spinal Cord; Valine | 1986 |
Continuously infused 2-amino-7-phosphonoheptanoic acid antagonizes N-methyl-D-aspartate-induced elevations of cyclic GMP in vivo in multiple brain areas and chemically-induced seizure activity.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Barbiturates; Bicuculline; Brain; Brain Chemistry; Cyclic GMP; Female; Injections, Intraventricular; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains | 1986 |
Deep prepyriform cortex kindling and its relation to amygdala kindling in the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; N-Methylaspartate; Rats; Valine | 1986 |
Stimulatory effect of N-methyl aspartate on locomotor activity and transmitter release from rat nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Aspartic Acid; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Motor Activity; N-Methylaspartate; Nialamide; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Valine | 1986 |
Blockade by D-aminophosphonovalerate or Mg2+ of excitatory amino acid-induced responses on spinal motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electric Conductivity; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Synaptic Transmission; Valine | 1986 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Rats; Structure-Activity Relationship; Valine | 1987 |
Excitatory amino acids and intracellular pH in motoneurons of the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Valine | 1986 |
Aortic baroreceptor reflexes are mediated by NMDA receptors in caudal ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Aspartic Acid; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Medulla Oblongata; Microinjections; N-Methylaspartate; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Synaptic Transmission; Valine | 1987 |
Comparison of L-[3H]glutamate, D-[3H]aspartate, DL-[3H]AP5 and [3H]NMDA as ligands for NMDA receptors in crude postsynaptic densities from rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
The NMDA receptor antagonist 2-amino-5-phosphonovalerate blocks stimulus train-induced epileptogenesis but not epileptiform bursting in the rat hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Postsynaptic control of hippocampal long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Evoked Potentials; GABA Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Picrotoxin; Synapses; Valine | 1986 |
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine | 1987 |
Cytoplasmic calcium elevation in hippocampal granule cell induced by perforant path stimulation and L-glutamate application.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Aspartic Acid; Benzofurans; Calcium; Cytoplasm; Egtazic Acid; Electric Stimulation; Fluorescent Dyes; Fura-2; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neural Pathways; Tetrodotoxin; Valine | 1987 |
Bursting in human epileptogenic neocortex is depressed by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anticonvulsants; Aspartic Acid; Epilepsy, Temporal Lobe; Humans; In Vitro Techniques; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Temporal Lobe; Valine | 1987 |
N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Aspartic Acid; Evoked Potentials, Visual; N-Methylaspartate; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Valine | 1987 |
The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Valine | 1987 |
Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apnea; Aspartic Acid; Blood Pressure; Carotid Sinus; Cats; Female; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Phrenic Nerve; Quisqualic Acid; Respiration; Vagotomy; Valine; Vasomotor System | 1987 |
Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellar Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Valine | 1987 |
Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Valine | 1987 |
Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia, General; Animals; Aspartic Acid; Drug Interactions; Female; Halothane; Hippocampus; Ketamine; N-Methylaspartate; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1987 |
Inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release by phencyclidine is dependent on potassium concentration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Magnesium Sulfate; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Potassium; Rats; Rats, Inbred Strains; Valine | 1987 |
A role for the ventral surface of the medulla in regulation of nasal resistance.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Airway Resistance; Animals; Aspartic Acid; Blood Pressure; Cats; Lidocaine; Medulla Oblongata; N-Methylaspartate; Nose; Phrenic Nerve; Receptors, Amino Acid; Receptors, Neurotransmitter; Valine | 1987 |
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1987 |
Dual action of excitatory amino acids on the metabolism of inositol phosphates in striatal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Carbachol; Cells, Cultured; Corpus Striatum; Glutamates; Inositol Phosphates; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Sugar Phosphates; Valine | 1987 |
Intrathecal N-methyl-D-aspartate (NMDA) activates both nociceptive and antinociceptive systems.
Topics: 2-Amino-5-phosphonovalerate; Analgesia; Animals; Aspartic Acid; Behavior, Animal; Decerebrate State; Injections, Spinal; Male; N-Methylaspartate; Nociceptors; Pain; Rats; Valine | 1987 |
The effects of excitatory amino acids and their antagonists on the generation of motor activity in the isolated chick spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Chick Embryo; Convulsants; Dipeptides; In Vitro Techniques; Kynurenic Acid; Motor Activity; Motor Neurons; N-Methylaspartate; Spinal Cord; Valine | 1987 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Alkalosis; Animals; Aspartic Acid; Cerebral Cortex; Epilepsy; In Vitro Techniques; Ketamine; Magnesium Deficiency; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
The pharmacological selectivity of three NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hexamethonium Compounds; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Norepinephrine; Piperazines; Rats; Serotonin; Synaptic Transmission; Valine | 1988 |
A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Aspartic Acid; Atropine; Binding, Competitive; Dipeptides; Dynorphins; Hot Temperature; Kinetics; Male; N-Methylaspartate; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
A quantitative pharmacological analysis of some excitatory amino acid receptors in the mouse neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1988 |
An excitatory amino acid projection from ventromedial hypothalamus to periaqueductal gray in the rat: autoradiographic and electrophysiological evidence.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Autoradiography; Electric Stimulation; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reaction Time; Valine; Ventromedial Hypothalamic Nucleus | 1988 |
Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Antitussive Agents; Aspartic Acid; Cerebral Cortex; Dextromethorphan; Dextrorphan; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Levorphanol; Morphinans; N-Methylaspartate; Seizures; Valine | 1988 |
Solubilization of rat brain phencyclidine receptors in an active binding form that is sensitive to N-methyl-D-aspartate receptor ligands.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain Chemistry; Cell Membrane; Cholic Acid; Cholic Acids; Detergents; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Solubility; Valine | 1988 |
NMDA- and kainate-evoked GABA release from striatal neurones differentiated in primary culture: differential blocking by phencyclidine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1988 |
Differential control by N-methyl-D-aspartate and kainate of striatal dopamine release in vivo: a trans-striatal dialysis study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Atropine; Carbachol; Corpus Striatum; Dopamine; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
Amino acids modulate calcium permeability of the plasma membrane of human neuroblastoma cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Calcium; Cell Membrane Permeability; Cysteine; Humans; Kainic Acid; N-Methylaspartate; Neuroblastoma; Neurotransmitter Agents; Tumor Cells, Cultured; Valine | 1988 |
Effects of excitatory amino acids on the oxygen consumption of hippocampal slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Oxygen Consumption; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spider Venoms; Valine | 1988 |
Influence of dynorphin (1-13) on spinal reflexes in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dynorphins; Electrophysiology; Injections, Spinal; Male; N-Methylaspartate; Nerve Fibers; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Reflex; Spinal Cord; Valine | 1988 |
Quantitative correlation between tetanus-induced decreases in extracellular calcium and LTP.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Calcium; Electric Stimulation; Extracellular Space; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Homocysteine; Iontophoresis; Ketamine; Male; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Valine | 1988 |
Glycine reverses antagonism of N-methyl-D-aspartate (NMDA) by 1-hydroxy-3-aminopyrrolidone-2 (HA-966) but not by D-2-amino-5-phosphonovalerate (D-AP5) on rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Evoked Potentials; Glycine; In Vitro Techniques; N-Methylaspartate; Pyrrolidinones; Rats; Valine | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrodotoxin; Valine | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cations, Divalent; Cells, Cultured; Glycine; Hippocampus; Ketamine; Kynurenic Acid; Magnesium; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Zinc | 1988 |
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
Glycine potentiates strychnine-induced convulsions: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Drug Synergism; Glycine; Injections, Spinal; Mice; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Strychnine; Valine | 1988 |
Long-term potentiation differentially affects two components of synaptic responses in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Somatosensory; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Synapses; Valine | 1988 |
Kynurenic acid and AP5 distinguish between NMDA receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Ibotenic Acid; Kynurenic Acid; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Do N-methyl-D-aspartate receptors mediate synaptic responses in the mudpuppy retina?
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Aspartic Acid; Electroretinography; Light; N-Methylaspartate; Necturus maculosus; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Stereoisomerism; Synapses; Valine | 1988 |
Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate and glutamine in mouse brain cortex.
Topics: 2-Amino-5-phosphonovalerate; 3-Mercaptopropionic Acid; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Male; Mice; N-Methylaspartate; Valproic Acid | 1988 |
Amino acid pharmacology in neocortical slices: evidence for bimolecular actions from an extension of the Hill and Gaddum-Schild equations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kynurenic Acid; Mathematics; Mice; N-Methylaspartate; Pyridines; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; In Vitro Techniques; N-Methylaspartate; Neurons; Piperazines; Rats; Reflex; Spine; Valine | 1988 |
NMDA receptor blockade prevents the increase in protein kinase C substrate (protein F1) phosphorylation produced by long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; GAP-43 Protein; Hippocampus; Kinetics; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Reference Values; Valine | 1988 |
Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebellum; Electric Stimulation; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quisqualic Acid; Turtles; Valine | 1988 |
N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antigens, Surface; Aspartic Acid; Cell Adhesion Molecules; Cell Survival; Cells, Cultured; Cerebellum; N-Methylaspartate; Nerve Tissue Proteins; Potassium; Rats; Rats, Inbred Strains; Valine | 1988 |
Stimulation of NMDA receptors induces proteolysis of spectrin in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Calcium Chloride; Evoked Potentials; Hippocampus; Hydrolysis; In Vitro Techniques; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spectrin; Valine | 1988 |
D-aminophosphonovaleric acid-sensitive spontaneous giant EPSPs in immature rat hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Piperazines; Rats; Synapses; Tetrodotoxin; Valine | 1988 |
Evidence for a specific role for cortical NMDA receptors in slow-wave sleep.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebral Cortex; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sleep; Valine | 1988 |
Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Electroencephalography; Hypoglycemia; Male; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1985 |
Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electroencephalography; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Stereotaxic Techniques; Substantia Nigra; Synaptic Transmission | 1986 |
2-Amino-7-phosphonoheptanoic acid, a selective N-methyl-D-aspartate antagonist, blocks swim-induced elevation of cerebellar cyclic guanosine monophosphate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Female; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Swimming | 1986 |
Both competitive and non-competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Light; Male; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred F344 | 1988 |
Excitatory amino acids in synaptic excitation of rat striatal neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Glutamates; Glutamine; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Synapses | 1988 |
The discriminative stimulus effects of N-methyl-D-aspartate antagonists in phencyclidine-trained rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Discrimination, Psychological; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Methohexital; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Time Factors | 1988 |
The N-methyl-D-aspartate antagonist, 2-amino-7-phosphonoheptanoate, produces phencyclidine-like behavioral effects in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1987 |
Effects of L-cysteine-sulphinate and L-aspartate, mixed excitatory amino acid agonists, on the membrane potential of cat caudate neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Cysteine; Female; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1987 |
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors | 1987 |
A simple method for quantitative electroencephalographic assessment of drugs with convulsant and anticonvulsant properties.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Diazepam; Electroencephalography; Hippocampus; Injections; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1986 |
N-Methyl-D-aspartate and L-aspartate activate distinct receptors in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Limbic System; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1984 |
2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anura; Aspartic Acid; Cats; Evoked Potentials; N-Methylaspartate; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Synapses | 1981 |
Pharmacological antagonists of excitant amino acid action.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Drug; Structure-Activity Relationship | 1981 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
D-aminophosphonovalerate is 100-fold more powerful than D-alpha-aminoadipate in blocking N-methylaspartate neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; Female; Hypothalamus; Male; Mice; N-Methylaspartate; Neurons; Organophosphorus Compounds; Structure-Activity Relationship; Valine | 1981 |
Some effects of excitatory amino acid receptor antagonists on synaptic transmission in the rat olfactory cortex slice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Aspartic Acid; Culture Techniques; Dipeptides; Electric Stimulation; Evoked Potentials; N-Methylaspartate; Olfactory Bulb; Olfactory Pathways; Pipecolic Acids; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine | 1982 |
Actions of N-methyl aspartate and its antagonist aminophosphonovalerate on the A5 catecholamine cell group in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Blood Pressure; Brain; Dose-Response Relationship, Drug; Female; Heart Rate; Male; N-Methylaspartate; Neurons; Rats; Receptors, Adrenergic; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Valine | 1982 |
Characterization of the excitatory amino acid receptor-mediated release of [3H]acetylcholine from rat striatal slices.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Afferent Pathways; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 1982 |
Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Stem; Cells, Cultured; Embryo, Mammalian; Glutamates; Ibotenic Acid; N-Methylaspartate; Oxazoles; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1983 |
The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Valine | 1983 |
Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rats; Synapses; Valine | 1983 |
A comparison of the anticonvulsant potency of (+/-) 2-amino-5-phosphonopentanoic acid and (+/-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Valine | 1983 |
Amino acid neurotransmission between fimbria-fornix fibers and neurons in the lateral septum of the rat: a microiontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Iontophoresis; Male; N-Methylaspartate; Nerve Fibers; Neural Pathways; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Septal Nuclei; Synaptic Transmission; Valine | 1984 |
A comparison of the effects of N-methyl-D-aspartate and quinolinate on central neurones of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Iontophoresis; Microinjections; N-Methylaspartate; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats; Somatosensory Cortex; Spinal Cord; Stimulation, Chemical; Valine | 1984 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Seizures | 1982 |
In vivo release of [3H]-purines by quinolinic acid and related compounds.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Kynurenic Acid; Male; N-Methylaspartate; Purines; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium | 1983 |
On the interaction of 2-amino-7-phosphono-heptanoic acid and quinolinic acid in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Iontophoresis; Male; Mice; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Seizures | 1983 |
Isomers of 2-amino-7-phosphonoheptanoic acid as antagonists of neuronal excitants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats | 1982 |
NMDA-induced burst discharge in guinea pig trigeminal motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Microelectrodes; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channels; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Trigeminal Nerve | 1995 |
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Apnea; Blood Pressure; Cats; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Piperazines; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Respiration; Solitary Nucleus; Vagotomy | 1995 |
Pharmacological evidence for involvement of excitatory amino acids in aversive responses induced by intrathecal substance P in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Biphenyl Compounds; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P | 1993 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Stimulation of N-methyl-D-aspartate receptors in the rat nucleus reticularis thalami suppresses somatosensory evoked potentials.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Somatosensory; Male; Microinjections; N-Methylaspartate; Nerve Fibers; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thalamic Nuclei | 1994 |
Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Ischemia; Cochlea; Cochlear Microphonic Potentials; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Male; N-Methylaspartate; Neurons, Afferent; Neurotransmitter Agents; Perfusion; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1994 |
N-methyl-D-aspartate receptors modulate extracellular 5-hydroxytryptamine concentration in rat hippocampus and striatum in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Extracellular Space; Hippocampus; Hydroxyindoleacetic Acid; Male; Microdialysis; N-Methylaspartate; Neostriatum; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serotonin; Tetrodotoxin | 1994 |
Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cell Line; Cycloleucine; Dizocilpine Maleate; Glioma; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Ion Channels; Kainic Acid; Kinetics; Magnesium Chloride; N-Methylaspartate; Neurotoxins; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Signal Transduction; Tumor Cells, Cultured | 1994 |
Inhibitory effects of anesthetics on cyclic guanosine monophosphate (cGMP) accumulation in rat cerebellar slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Anesthetics; Animals; Cerebellum; Cyclic GMP; Halothane; In Vitro Techniques; N-Methylaspartate; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Thiopental | 1994 |
Thyrotropin-releasing hormone enhances excitatory postsynaptic potentials in neocortical neurons of the rat in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Stimulation; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Thyrotropin-Releasing Hormone | 1994 |
Modulation of neuropeptide FF release from rat spinal cord slices by glutamate. Involvement of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dizocilpine Maleate; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Membranes; N-Methylaspartate; Neuropeptides; Neurotoxins; Oligopeptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
NMDA receptor involvement in endothelin neurotoxicity in rat striatal slices.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dopamine; Endothelins; In Vitro Techniques; Male; N-Methylaspartate; Neostriatum; Neurons; Nifedipine; Potassium; Potassium Chloride; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Changes of extracellular calcium concentration induced by application of excitatory amino acids in the human neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Humans; In Vitro Techniques; Injections; Male; Membrane Potentials; N-Methylaspartate | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Regulation of spontaneous phasic firing of rat supraoptic vasopressin neurones in vivo by glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Kainic Acid; Male; N-Methylaspartate; Oxytocin; Rats; Receptors, Glutamate; Supraoptic Nucleus; Vasopressins | 1995 |
Intrathecal administration of N-methyl-D-aspartate receptor antagonist reduces the minimum alveolar anaesthetic concentration of isoflurane in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Inhalation; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Isoflurane; Male; N-Methylaspartate; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Calcium-dependent glutamate release during neuronal development and synaptogenesis: different involvement of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Cells, Cultured; Fetus; Glutamic Acid; Glycine; Hippocampus; Kinetics; Magnesium; N-Methylaspartate; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Rats; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Synapses; Time Factors | 1995 |
N-methyl-D-aspartate receptors outside the central nervous system: activation causes acute lung injury that is mediated by nitric oxide synthesis and prevented by vasoactive intestinal peptide.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cyclic GMP; Lung Diseases; N-Methylaspartate; Nitric Oxide; Organ Size; Peripheral Nervous System; Rats; Receptors, N-Methyl-D-Aspartate; Vasoactive Intestinal Peptide | 1995 |
Cardiovascular effects of NMDA in the RVLM of spontaneously hypertensive rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Carotid Arteries; Electric Stimulation; Hemodynamics; Hypertension; Male; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Vagotomy | 1995 |
Blockade of L-glutamate receptors in the rostral ventrolateral medulla contributes to ethanol-evoked impairment of baroreflexes in conscious rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baroreflex; Blood Pressure; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Long-term potentiation in the piriform cortex is blocked by lead.
Topics: 2-Amino-5-phosphonovalerate; Animals; Child; Evoked Potentials; Humans; In Vitro Techniques; Intelligence; Lead; Lead Poisoning; Long-Term Potentiation; Male; N-Methylaspartate; Olfactory Pathways; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Activity-dependent responses of developing cochlear nuclear neurons to microionophoretically-applied amino acids.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Acoustic Stimulation; Action Potentials; Animals; Auditory Threshold; Bicuculline; Cats; Cochlear Nucleus; gamma-Aminobutyric Acid; Glutamic Acid; Iontophoresis; N-Methylaspartate; Neurons; Synaptic Transmission | 1995 |
Rapid acquisition of dendritic spines by visual thalamic neurons after blockade of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Dendrites; Female; Ferrets; Geniculate Bodies; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate; Reference Values | 1995 |
Frequency dependent activation of a slow N-methyl-D-aspartate-dependent excitatory postsynaptic potential in turtle cerebellum by mossy fibre afferents.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Bicuculline; Cerebellum; Electric Stimulation; Evoked Potentials; N-Methylaspartate; Presynaptic Terminals; Purkinje Cells; Turtles | 1995 |
Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Brain; Chromosome Mapping; Chromosomes, Human, Pair 9; Cricetinae; Dizocilpine Maleate; DNA; Humans; Hybrid Cells; Karyotyping; Kynurenic Acid; Macromolecular Substances; Magnesium; Molecular Sequence Data; N-Methylaspartate; Oocytes; Poly A; Receptors, N-Methyl-D-Aspartate; RNA; RNA, Messenger; Temporal Lobe; Xenopus; Zinc | 1993 |
The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biphenyl Compounds; Capsaicin; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurokinin A; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Spinal Cord; Substance P; Synapses; Synaptic Transmission | 1993 |
N-methyl-D-aspartate induces regular firing patterns in the cat lateral habenula in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Ibotenic Acid; Iontophoresis; Kainic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Stereotaxic Techniques; Thalamus | 1993 |
Norbinaltorphimine protection against N-methyl-D-aspartic acid-induced convulsions and mortality.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Binding, Competitive; Brain; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Naltrexone; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; DNA, Neoplasm; Glutamates; Glutamic Acid; Glycine; Humans; Ion Channels; Kinetics; Magnesium; Membrane Potentials; Molecular Sequence Data; N-Methylaspartate; Neurons; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; RNA, Neoplasm; Sequence Homology, Amino Acid; Teratoma; Tumor Cells, Cultured | 1993 |
Further studies concerning the role of nitric oxide in LTP induction and maintenance.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Electric Stimulation; Evoked Potentials; Free Radical Scavengers; Hemoglobins; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuronal Plasticity; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Potassium Channels; Rats; Rats, Sprague-Dawley; Synapses; Tetraethylammonium Compounds | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
NMDA receptors mediate neuronal burst firing in rat somatosensory cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1993 |
Kainate toxicity in energy-compromised rat hippocampal slices: differences between oxygen and glucose deprivation.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Electrophysiology; Energy Metabolism; Evoked Potentials; Glucose; Hippocampus; Hypoxia, Brain; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
N-Methyl-D-aspartate receptors are clustered and immobilized on dendrites of living cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Conotoxins; Dendrites; Evoked Potentials; Ibotenic Acid; Magnesium; Membrane Potentials; Mollusk Venoms; N-Methylaspartate; Neurons; Peptides, Cyclic; Pyramidal Tracts; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Pentamidine, an inhibitor of spinal flexor reflexes in rats, is a potent N-methyl-D-aspartate (NMDA) antagonist in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Drug Interactions; Electromyography; H-Reflex; Ibotenic Acid; Injections, Spinal; Male; N-Methylaspartate; Pentamidine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Stretch; Tibial Nerve | 1993 |
The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rana pipiens; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Tetrodotoxin; Thalamus | 1993 |
Effects of L-glutamate, substance P and substance P(1-7) on cardiovascular regulation in the nucleus tractus solitarius.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Molecular Sequence Data; N-Methylaspartate; Peptide Fragments; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Reference Values; Stereotaxic Techniques; Substance P | 1993 |
Nitric oxide inhibitors facilitate the induction of hippocampal long-term potentiation by modulating NMDA responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Arginine; Culture Techniques; Hippocampus; Long-Term Potentiation; Male; Membrane Potentials; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Tolerance to competitive NMDA antagonists, but no crosstolerance with barbiturates.
Topics: 2-Amino-5-phosphonovalerate; Animals; Ataxia; Behavior, Animal; Dizocilpine Maleate; Drug Tolerance; Hypnotics and Sedatives; Male; Mice; Motor Activity; N-Methylaspartate; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome | 1995 |
Morphine selectively depresses the slowest, NMDA-independent component of C-fibre-evoked synaptic activity in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Morphine; N-Methylaspartate; Naloxone; Rats; Spinal Cord; Synapses | 1995 |
Influence of NMDA receptor ligands on thyrotropin-releasing hormone-induced scratching in rabbits.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding, Competitive; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Injections, Intraventricular; Ligands; Male; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Thyrotropin-Releasing Hormone | 1995 |
Changes in prepulse inhibition after local administration of NMDA receptor ligands in the core region of the rat nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Hippocampus; Male; N-Methylaspartate; Nucleus Accumbens; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
Stimulation of glutamate receptors in the intermediate/caudal striatum induces contralateral turning.
Topics: 2-Amino-5-phosphonovalerate; Animals; Caudate Nucleus; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Injections; Male; N-Methylaspartate; Neostriatum; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1995 |
Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Brain; Brain Diseases; Embryonic and Fetal Development; Excitatory Amino Acids; Female; Glial Fibrillary Acidic Protein; Hypoxia; Ibotenic Acid; Male; Mice; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
N-methyl-D-aspartate receptors modulate neurotransmitter release and peristalsis in the guinea pig isolated colon.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Colon; Glutamic Acid; Guinea Pigs; Magnesium; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Peristalsis; Receptors, N-Methyl-D-Aspartate | 1995 |
Ethanol effects of NMDA-stimulated levels of extracellular neurotransmitters by in vivo microdialysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Ethanol; Extracellular Space; Male; Microdialysis; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Postnatal changes in the role of NMDA in the isolated spinal cord of the hamster, Mesocricetus auratus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aging; Animals; Cricetinae; In Vitro Techniques; Magnesium; Mesocricetus; N-Methylaspartate; Spinal Cord | 1994 |
Effects of excitatory amino acid antagonists on the phasic depolarizing events that occur in lumbar motoneurons during REM periods of active sleep.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electrooculography; Evoked Potentials; Excitatory Amino Acid Antagonists; Kynurenic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Sciatic Nerve; Sleep, REM; Spinal Cord; Synaptic Transmission | 1995 |
The competitive NMDA antagonist CGP 40116 permanently reduces brain damage after middle cerebral artery occlusion in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cerebral Arteries; Constriction; Glial Fibrillary Acidic Protein; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; N-Methylaspartate; Rats; Rats, Inbred F344 | 1995 |
Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Cell Division; Cell Survival; Dizocilpine Maleate; DNA; Hippocampus; Homeostasis; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S Phase; Thymidine; Time Factors | 1995 |
No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Electric Stimulation; Hyperalgesia; In Vitro Techniques; N-Methylaspartate; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Reflex; Spinal Cord; Spinal Nerve Roots | 1995 |
Effects of microinjection of N-methyl-D-aspartic acid into the nucleus tractus solitarii on cerebral blood flow in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Pressure; Cerebrovascular Circulation; Male; Microinjections; Microspheres; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Vascular Resistance | 1994 |
Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Glycine; Hippocampus; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1994 |
Bilateral intranigral NMDA blockade increases status duration and neuronal injury from systemic kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Carbon Dioxide; Diazepam; Drug Synergism; Electroencephalography; Functional Laterality; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Injections, Intravenous; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neurons; Oxygen; Partial Pressure; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors | 1994 |
NMDA-mediated potentiation of the afferent synapse in the inner ear.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Amplifiers, Electronic; Animals; Dizocilpine Maleate; Electrophysiology; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Physical Stimulation; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synapses; Vestibule, Labyrinth | 1994 |
Modulatory effect of plasminogen on NMDA-induced increase in intracellular free calcium concentration in rat cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Hippocampus; N-Methylaspartate; Neurons; Plasminogen; Rats; Rats, Wistar; Synapses; Tetrodotoxin | 1994 |
Synergistic interactions between NMDA-antagonists and L-dopa on activity in MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1994 |
Volatile anesthetics inhibit NMDA-stimulated 45Ca uptake by rat brain microvesicles.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Calcium; Calcium Radioisotopes; Dizocilpine Maleate; Enflurane; Glycine; Halothane; Kinetics; Male; Microcirculation; N-Methylaspartate; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
N-methyl-D-aspartate (NMDA) stimulates release of alpha-MSH from the rat hypothalamus through release of nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; alpha-MSH; Animals; Arginine; Hypothalamus; Ketamine; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Rats; Rats, Wistar | 1994 |
Regulation of dopamine levels in intrastriatal grafts of fetal mesencephalic cell suspension: an in vivo voltammetric approach.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzazepines; Brain Tissue Transplantation; Cerebral Ventricles; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Female; Fetal Tissue Transplantation; Glutamic Acid; Injections, Intraventricular; Kinetics; Mesencephalon; N-Methylaspartate; Oxidopamine; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Sulpiride; Time Factors; Transplantation, Heterotopic | 1994 |
Regulation of N-methyl-D-aspartate receptor-mediated calcium transport and norepinephrine release in rat hippocampus synaptosomes by polyamines.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biological Transport; Calcium; Eflornithine; Egtazic Acid; Female; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Synaptosomes | 1994 |
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine | 1993 |
Effect of systemic administration of N-methyl-D-aspartic acid on extracellular taurine level measured by microdialysis in the hippocampal CA1 field and striatum of rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Extracellular Space; Hippocampus; Injections, Intraperitoneal; Kinetics; Male; Microdialysis; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Wistar; Taurine; Time Factors | 1993 |
Further evidence for multiple forms of an N-methyl-D-aspartate recognition domain in rat brain using membrane binding techniques.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Brain; Dithionitrobenzoic Acid; Dizocilpine Maleate; Ethylmaleimide; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Reagents; Synaptic Membranes | 1993 |
nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine | 1993 |
Stress-induced dopamine release in the neostriatum: evaluation of the role of action potentials in nigrostriatal dopamine neurons or local initiation by endogenous excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corpus Striatum; Dopamine; Electroshock; Homovanillic Acid; Kainic Acid; Male; N-Methylaspartate; Neostriatum; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Stress, Psychological; Substantia Nigra; Tetrodotoxin | 1993 |
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Learning; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatostatin; Space Perception | 1993 |
Excitatory amino acid-induced phosphoinositide hydrolysis in Müller glia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Chickens; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Retina; Tritium | 1993 |
Calcium-mediated damage following hypoxia in cerebral cortex ex vivo studied by NMR spectroscopy. Evidence for direct involvement of voltage-gated Ca(2+)-channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Diltiazem; Excitatory Amino Acid Antagonists; Hydrogen; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Magnesium; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Phosphocreatine; Phosphorus; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
Pharmacological and electrographic properties of epileptiform activity induced by elevated K+ and lowered Ca2+ and Mg2+ concentration in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Carbachol; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quaternary Ammonium Compounds; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Temperature | 1993 |
Influence of the organic calcium antagonist verapamil on N-methyl-D-aspartate (NMDA) induced cortical field potentials (neocortical slice, guinea pig).
Topics: 2-Amino-5-phosphonovalerate; Algorithms; Animals; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Motor Cortex; N-Methylaspartate; Somatosensory Cortex; Verapamil | 1993 |
Synaptic excitation triggers oscillations during NMDA receptor activation in rat abducens motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Abducens Nerve; Animals; Dizocilpine Maleate; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Ketamine; Male; Motor Neurons; N-Methylaspartate; Oscillometry; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Involvement of amygdala N-methyl-D-asparate receptors in long-term retention of an inhibitory avoidance response in rats.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Avoidance Learning; Dizocilpine Maleate; Long-Term Potentiation; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retention, Psychology | 1993 |
Stereotypical changes in the pattern and duration of long-term potentiation expressed at postnatal days 11 and 15 in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrodes; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Determinants of non-spatial working memory deficits in rats given intraventricular infusions of the NMDA antagonist AP5.
Topics: 2-Amino-5-phosphonovalerate; Animals; Conditioning, Operant; Habituation, Psychophysiologic; Handling, Psychological; Injections, Intraventricular; Male; Memory, Short-Term; N-Methylaspartate; Rats; Rats, Inbred Strains; Stereotaxic Techniques | 1993 |
Conantokin-G antagonism of the NMDA receptor subtype expressed in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Conotoxins; Cytoplasmic Granules; Electrophysiology; Fura-2; N-Methylaspartate; Peptides, Cyclic; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Inhibition by ascorbic acid of NMDA-evoked acetylcholine release in rabbit caudate nucleus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Ascorbic Acid; Caudate Nucleus; Dehydroascorbic Acid; Electric Stimulation; N-Methylaspartate; Rabbits | 1993 |
Characterization of the role of spinal N-methyl-D-aspartate receptors in thermal nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cold Temperature; Hot Temperature; Male; Methysergide; N-Methylaspartate; Nitroarginine; Nociceptors; Pain; Phentolamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1993 |
Evidence for NMDA receptor in the afferent synaptic transmission of the vestibular system.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Animals; Glycine; Hair Cells, Auditory; In Vitro Techniques; Kynurenic Acid; Magnesium; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Receptors, N-Methyl-D-Aspartate; Semicircular Canals; Synapses; Synaptic Transmission; Vestibule, Labyrinth | 1994 |
Modulation of alcohol preference by NMDA antagonists in male rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain; Capillary Permeability; Choice Behavior; Ethanol; Magnesium; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1993 |
NMDA receptors with different sensitivities to magnesium and ifenprodil control the release of [14C]acetylcholine and [3H]spermidine from rat striatal slices in vitro.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aminoquinolines; Animals; Carbon Radioisotopes; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Magnesium; Magnesium Chloride; N-Methylaspartate; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Tritium | 1994 |
The ACTH(4-9) analog Org2766 modulates the behavioral changes induced by NMDA and the NMDA receptor antagonist AP5.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Drug Combinations; Injections, Intraventricular; Male; Motor Activity; N-Methylaspartate; Peptide Fragments; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 1994 |
Modulation of muscarinic cholinoceptor-stimulated inositol 1,4,5-trisphosphate accumulation by N-methyl-D-aspartate in neonatal rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Carbachol; Cerebral Cortex; Dizocilpine Maleate; Female; Glycine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Magnesium; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Muscarinic | 1994 |
Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Aged, 80 and over; Cell Division; Cells, Cultured; Dizocilpine Maleate; DNA; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Middle Aged; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction | 1993 |
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium | 1994 |
Involvement of amino acids, opioids, nitric oxide, and NMDA receptors in learning and memory consolidation in crickets.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Conditioning, Operant; Endorphins; Female; Gryllidae; Hemoglobins; Learning; Memory; N-Methylaspartate; Naloxone; Nitric Oxide; Receptors, N-Methyl-D-Aspartate | 1994 |
Hippocampal plasticity following epileptiform bursting produced by GABAA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Epilepsy; Evoked Potentials; GABA Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Penicillins; Pyramidal Cells; Seizures; Time Factors | 1994 |
Possible involvement of NMDA receptor-mediated transmission in barbiturate physical dependence.
Topics: 2-Amino-5-phosphonovalerate; Animals; Barbital; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Hippocampus; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome | 1994 |
Evidence that arcaine increases the N-methyl-D-aspartate-induced cardiovascular effects into the periaqueductal gray area of anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Biguanides; Blood Pressure; Dizocilpine Maleate; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Male; N-Methylaspartate; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Possible NMDA antagonist properties of drugs that affect high pressure neurological syndrome.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Alkaloids; Animals; Benzimidazoles; High Pressure Neurological Syndrome; Hippocampus; Indole Alkaloids; Kynurenic Acid; Mephenesin; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1994 |
Changes in cytosolic sodium caused by a toxic glutamate treatment of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Culture Techniques; Cytosol; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Magnesium; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Wistar; Sodium; Time Factors; Veratridine | 1994 |
NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Hypoxia; Dizocilpine Maleate; Evoked Potentials; Female; In Vitro Techniques; Ketamine; N-Methylaspartate; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Modulatory effects of NMDA on phosphoinositide responses evoked by the metabotropic glutamate receptor agonist 1S,3R-ACPD in neonatal rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Calcium; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Female; Hydrolysis; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; N-Methylaspartate; Neurotoxins; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Acute tolerance to ethanol inhibition of NMDA-mediated EPSPs in the CA1 region of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Drug Tolerance; Ethanol; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 1994 |
Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Dizocilpine Maleate; Embryo, Mammalian; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Fos protein induction, neuropathology, and pharmacological protection after excitotoxic brain insult.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Injections; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Time Factors | 1994 |
Intra-amygdala infusion of the N-methyl-D-aspartate receptor antagonist AP5 impairs acquisition but not performance of discriminated approach to an appetitive CS.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Appetitive Behavior; Behavior, Animal; Conditioning, Psychological; Learning; Locomotion; Male; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Release of adenosine by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Enkephalins; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Male; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Theophylline | 1994 |
Spinal cord excitatory amino acids and cardiovascular autonomic responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardiovascular System; Heart Rate; N-Methylaspartate; Quinoxalines; Rabbits; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Vasoconstriction | 1994 |
NMDA-dependent audiogenic seizures are differentially regulated by inferior colliculus subnuclei.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Brain Mapping; Epilepsy, Tonic-Clonic; Inferior Colliculi; N-Methylaspartate; Neurons; Rats; Seizures; Synaptic Transmission | 1994 |
NMDA and quisqualate modulation of visceral nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Colon; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Rectum | 1994 |
Sigma-receptor regulation of [3H]arachidonic acid release from rat neonatal cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Arachidonic Acid; Binding, Competitive; Cell Membrane; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Haloperidol; Kinetics; Melitten; N-Methylaspartate; Neurons; Pentazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Tritium | 1994 |
Preferential induction by stress of the N-methyl-D-aspartate recognition domain in discrete structures of rat brain.
Topics: 2-Amino-5-phosphonovalerate; Adrenal Cortex Hormones; Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Cerebellum; Corpus Striatum; Cycloheximide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glycine; Hypothalamus; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Stress, Physiological; Tritium | 1994 |
Subcutaneous formalin produces centrifugal hyperalgesia at a non-injected site via the NMDA-nitric oxide cascade.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cordotomy; Formaldehyde; Hot Temperature; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
Nitric oxide alters proenkephalin and prodynorphin gene expression in hippocampal granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Cyclic GMP; Dendrites; Enkephalins; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Molecular Sequence Data; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Protein Precursors; Rats; RNA, Messenger; Vasodilator Agents | 1994 |
Glutamate and N-methyl-D-aspartate affect release from crayfish axon terminals in a voltage-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Astacoidea; Axons; Calcium; Glutamates; Magnesium; Membrane Potentials; N-Methylaspartate; Neural Conduction; Neuromuscular Junction; Neurotransmitter Agents; Synaptic Transmission | 1994 |
An ADP-ribosyltransferase as a potential target for nitric oxide action in hippocampal long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cyclic GMP; Dibutyryl Cyclic GMP; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Molsidomine; N-Methylaspartate; NAD; Niacinamide; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1994 |
Differential effects of compounds that act at strychnine-insensitive glycine receptors in a punishment procedure.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Diazepam; Learning; Male; Memory; Mice; N-Methylaspartate; Punishment; Reaction Time; Receptors, Glycine; Strychnine | 1994 |
Potent quinoxaline-spaced phosphono alpha-amino acids of the AP-6 type as competitive NMDA antagonists: synthesis and biological evaluation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; In Vitro Techniques; Male; Mice; Models, Molecular; Molecular Conformation; N-Methylaspartate; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Proconvulsant and anticonvulsant properties of ethanol: studies of electrographic seizures in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Electric Stimulation; Ethanol; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Seizures | 1993 |
Long-term potentiation in hippocampal CA1: effects of afterdischarges, NMDA antagonists, and anticonvulsants.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dizocilpine Maleate; Electrophysiology; Hippocampus; Male; N-Methylaspartate; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Reaction Time; Synapses | 1993 |
Development of glutamate and NMDA sensitivity of neurons within the cochlear nuclear complex of kittens.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Acoustic Stimulation; Age Factors; Animals; Brain Mapping; Cats; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials, Auditory; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
Entorhinal cortex long-term potentiation evoked by theta-patterned stimulation of associative fibers in the isolated in vitro guinea pig brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Guinea Pigs; In Vitro Techniques; N-Methylaspartate; Nerve Fibers; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Carbachol; Cycloheximide; Dendrites; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Leucine; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Pyramidal Tracts; Receptors, Muscarinic; Tritium | 1993 |
The effects of intrathecal administration of excitatory amino acid agonists and antagonists on the initiation of locomotion in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Decerebrate State; Electromyography; Glutamates; Glutamic Acid; Hindlimb; Injections, Spinal; Kainic Acid; Laminectomy; Locomotion; Motor Activity; Muscles; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Spinal Cord; Time Factors | 1993 |
Long-lasting potentiation of synaptic transmission in the Schaffer collateral-commissural pathway of the guinea pig hippocampus by activation of postsynaptic N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Spermine; Synapses; Synaptic Transmission | 1993 |
Optical imaging of parallel fiber activation in the rat cerebellar cortex: spatial effects of excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebellar Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Involvement of excitatory amino acids in the activity of swallowing-related neurons of the ventro-lateral medulla.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Dipeptides; Electric Stimulation; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
Modulation of neuronal migration by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Calcium; Cell Movement; Cerebellum; Dizocilpine Maleate; Egtazic Acid; Glutamates; Glutamic Acid; Glycine; Magnesium; Mice; N-Methylaspartate; Neurons; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate metabotropic receptor mediated depression of synaptic inputs to lamprey reticulospinal neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Cycloleucine; Electric Stimulation; Electrophysiology; Evoked Potentials; GTP-Binding Proteins; Ketamine; Lampreys; Microelectrodes; N-Methylaspartate; Neurons; Receptors, Glutamate; Reticular Formation; Rhombencephalon; Spinal Cord; Synapses | 1993 |
Different proportions of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor currents at the mossy fibre-granule cell synapse of developing rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Bicuculline; Cerebellum; Cytoplasmic Granules; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kinetics; Magnesium; N-Methylaspartate; Nerve Fibers; Neurons; Neurons, Afferent; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1993 |
An experimental arthritis model in rats: the effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Aspartic Acid; Carrageenan; Glutamates; Glutamic Acid; Injections, Intra-Articular; Kaolin; Knee Joint; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
Differential effects of GABAA and GABAB receptor agonists on NMDA-induced and noradrenaline-induced luteinizing-hormone release in the ovariectomized estrogen-primed rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Dose-Response Relationship, Drug; Estrogens; Female; Injections, Intraventricular; Luteinizing Hormone; Muscimol; N-Methylaspartate; Norepinephrine; Ovariectomy; Ovary; Phentolamine; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
Effect of excitatory amino acid on the hypothalamo-pituitary-adrenal axis in the rat during the stress-hyporesponsive period.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; Amino Acids; Animals; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Pituitary-Adrenal System; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Stress, Physiological | 1993 |
Cholecystokinin-induced ventral root depolarization of neonate rat hemicord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzodiazepinones; Cholecystokinin; Devazepide; Dose-Response Relationship, Drug; In Vitro Techniques; N-Methylaspartate; Neuromuscular Depolarizing Agents; Phenylurea Compounds; Rats; Receptors, Cholecystokinin; Spinal Cord; Tetrodotoxin | 1993 |
A developmental decrease in NMDA-mediated spontaneous firing in cultured rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Culture Media; Electrophysiology; Female; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1993 |
Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Female; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1993 |
In vivo regulation of extracellular dopamine in the neostriatum: influence of impulse activity and local excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Corpus Striatum; Dialysis; Dopamine; Exocytosis; Extracellular Space; Kainic Acid; Kynurenic Acid; Microchemistry; Models, Neurological; N-Methylaspartate; Nerve Endings; Neurotoxins; Prosencephalon; Quinoxalines; Rats; Substantia Nigra; Tetrodotoxin | 1993 |
Synchronous calcium oscillations in cerebellar granule cells in culture mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Image Processing, Computer-Assisted; Magnesium; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate neurons in hypothalamus regulate excitatory transmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hypothalamus; Microscopy, Electron; N-Methylaspartate; Neurites; Neurons; Quinoxalines; Rats; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
MK-801 and phencyclidine act at phencyclidine sites that are not linked to N-methyl-D-aspartate activity to inhibit behavioral sensitization to kainate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; N-Methylaspartate; Nociceptors; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord | 1993 |
Electrophysiological characterization of excitatory amino acid responses in rat lateral parabrachial neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Neurons; Pons; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Serine; Time Factors | 1993 |
Developmental alterations in N-methyl-D-aspartate stimulated [3H]norepinephrine release in rat brain cortex and hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley | 1993 |
Spermidine and cardiovascular control in nucleus tractus solitarii in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular System; Dizocilpine Maleate; Dose-Response Relationship, Drug; Heart Rate; Male; Methylene Blue; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Spermidine | 1993 |
Evidence for enhanced synaptic excitation in transplanted neostriatal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Fetal Tissue Transplantation; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission | 1993 |
Paroxysmal long-lasting depolarizations in cultured hippocampal neurons are generated by activation of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Magnesium; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1993 |
Contribution of spinal N-methyl-D-aspartic acid receptors to control of sympathetic outflow by the paraventricular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Electric Stimulation; Heart Rate; Injections, Spinal; Kainic Acid; Kidney; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Renal Circulation; Spinal Cord; Sympathetic Nervous System | 1993 |
[Effect of intracerebroventricular injection of N-methyl-D-aspartate on learning and memory in mice].
Topics: Animals; Female; Injections, Intraventricular; Learning; Male; Memory; Mice; N-Methylaspartate; Valine | 1993 |
N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of dextromethorphan in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Dextromethorphan; Electric Stimulation; Electromyography; H-Reflex; Injections, Intraperitoneal; Injections, Spinal; Male; Muscle Relaxation; Muscles; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reflex, Stretch | 1993 |
Manufacture and release characteristics of Elvax polymers containing glutamate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Carriers; Drug Implants; Excitatory Amino Acid Antagonists; Ferrets; Molecular Weight; N-Methylaspartate; Piperazines; Polyvinyls; Receptors, Glutamate | 1995 |
Ultrastructural damage and neuritic beading in cold-stressed spinal neurons with comparisons to NMDA and A23187 toxicity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcimycin; Calcium; Cells, Cultured; Cold Temperature; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ionophores; Mice; Microscopy, Electron; N-Methylaspartate; Neurites; Neurons; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Wounds and Injuries | 1995 |
Presynaptic actions of glutamate receptor agonists in the CA1 region of rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 1995 |
Metabotropic and ionotropic glutamate receptors mediate opposite effects on periaqueductal gray matter.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Blood Pressure; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Neurons; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
NMDA-dependent modulation of CA1 local circuit inhibition.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dipeptides; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Female; Hippocampus; Histamine H1 Antagonists; Long-Term Potentiation; Male; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Neural Inhibition; Phencyclidine; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Synaptic Transmission | 1996 |
Amygdaloid kindling by repeated focal N-methyl-D-aspartate administration: comparison with electrical kindling.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Calcium; Excitatory Amino Acid Agonists; Kindling, Neurologic; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
Evidence that gonadal steroids modulate nitric oxide efflux in the medial preoptic area: effects of N-methyl-D-aspartate and correlation with luteinizing hormone secretion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Female; Luteinizing Hormone; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
A comparison of the effect of halothane on N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated excitatory synaptic transmission in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Halothane; Hippocampus; Male; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1996 |
The role of GABA in NMDA-dependent long term depression (LTD) of rat medial vestibular nuclei.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Brain Stem; gamma-Aminobutyric Acid; Long-Term Potentiation; Membrane Potentials; N-Methylaspartate; Rats; Rats, Wistar; Time Factors; Vestibular Nuclei | 1995 |
The N-methyl-D-aspartate-mediated inhibitory control of gonadotropin-releasing hormone release in the hypothalamus of the adult male guinea pig is expressed through opioidergic systems.
Topics: 2-Amino-5-phosphonovalerate; Animals; Endorphins; Gonadotropin-Releasing Hormone; Guinea Pigs; Hypothalamus; Hypothalamus, Middle; Male; N-Methylaspartate; Naloxone; Orchiectomy; Sex Factors | 1996 |
Systemic NMDA antagonist CGP-37849 produces non-specific impairment in a working memory task: the effect does not resemble those of AP5 and of lesions of the hippocampus or fornix.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; Memory, Short-Term; Motor Activity; N-Methylaspartate; Rats | 1996 |
Septal and hippocampal glutamate receptors modulate the output of acetylcholine in hippocampus: a microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Septal Nuclei | 1996 |
Effects of excitatory amino acid receptor agonists and antagonists on the secretion of melatonin, luteinizing hormone and prolactin in the ram.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Luteinizing Hormone; Male; Melatonin; N-Methylaspartate; Photoperiod; Prolactin; Quinoxalines; Radioimmunoassay; Sheep | 1993 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists; N-Methylaspartate; N-Methylscopolamine; Nucleus Accumbens; Parasympatholytics; Scopolamine Derivatives; Stereotyped Behavior | 1995 |
Glutamate depresses release by activating non-conventional glutamate receptors at crayfish nerve terminals.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astacoidea; Axons; Calcium; Cell Membrane; Electric Conductivity; Electric Stimulation; Fura-2; Glutamic Acid; Muscles; N-Methylaspartate; Nerve Endings; Perfusion; Quisqualic Acid; Receptors, Glutamate; Synapses; Time Factors | 1996 |
Glutamate receptor ion channel properties predict vulnerability to cytotoxicity in a transfected nonneuronal cell line.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Benzothiadiazines; Cell Line; Cell Survival; Concanavalin A; Dizocilpine Maleate; DNA Primers; Evoked Potentials; Glutamic Acid; Humans; Ion Channels; Kainic Acid; Kidney; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Transfection | 1996 |
Progesterone in vitro increases NMDA-evoked [3H] dopamine release from striatal slices in proestrus rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Corpus Striatum; Dizocilpine Maleate; Dopamine; Drug Synergism; Estrus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; N-Methylaspartate; Progesterone; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
Characterisation of N-methyl-D-aspartate (NMDA)-induced kindling.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Anticonvulsants; Electroencephalography; Kindling, Neurologic; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors | 1996 |
Activation of serotonergic 5-HT1A receptor reduces Ca(2+)- and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acid; Buspirone; Calcium; Cyclic GMP; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Ketanserin; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Quinacrine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Synaptosomes | 1996 |
Characterization of glutamate binding sites in receptors assembled from transfected NMDA receptor subunits.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Cell Line; DNA, Complementary; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Structure-Activity Relationship; Transfection | 1996 |
Microinjection of NMDA antagonist into the NTS of conscious rats blocks the Bezold-Jarisch reflex.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia, Inhalation; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Heart Rate; Male; Microinjections; N-Methylaspartate; Nerve Fibers; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Synaptic Transmission | 1996 |
NMDA receptor blockade in cat dorsal horn blunts reflex pressor response to muscle contraction and stretch.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Lumbosacral Region; Microdialysis; Muscle Contraction; N-Methylaspartate; Osmolar Concentration; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1996 |
Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Weight; Circadian Rhythm; Eating; Excitatory Amino Acid Antagonists; Food Deprivation; Glutamic Acid; Hypothalamic Area, Lateral; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1996 |
Modulation of spinal visceral nociceptive transmission by NMDA receptor activation in the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Colon; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rectum; Serine; Skin; Spinal Cord; Synaptic Transmission | 1996 |
Use of subunit-specific antisense oligodeoxynucleotides to define developmental changes in the properties of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Base Sequence; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kynurenic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oligonucleotides, Antisense; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus laevis | 1996 |
N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Male; N-Methylaspartate; Neurons; Peripheral Nerve Injuries; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1996 |
Effects of excitatory amino acids on the hypothalamic-pituitary-adrenal axis of the neonatal rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenocorticotropic Hormone; Age Factors; Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hypothalamo-Hypophyseal System; Kainic Acid; Male; N-Methylaspartate; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Stress, Physiological; Time Factors | 1996 |
Intraseptal infusion of selective and competitive glutamate receptor agonist NMDA and antagonist D-2-amino-5-phosphonopentanoic acid spectral implications for the physostigmine-induced hippocampal theta rhythm in urethane-anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Microinjections; N-Methylaspartate; Physostigmine; Rats; Rats, Wistar; Septal Nuclei; Theta Rhythm; Urethane | 1996 |
Concentration-dependent dual action of locally applied N-methyl-D-aspartate on extracellular dopamine in the rat prefrontal cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Calcium; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Homovanillic Acid; Male; Microdialysis; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Wistar | 1995 |
Adrenocorticotrophin and luteinizing hormone responses to N-methyl-D-aspartate during fetal development in sheep.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; Animals; Embryonic and Fetal Development; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gestational Age; Luteinizing Hormone; N-Methylaspartate; Pituitary Gland, Anterior; Sheep | 1996 |
[The influence of intrathecal NMDA receptor antagonist on the isoflurane MAC and on the motor function].
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1996 |
N-methyl-D-aspartate acutely increases proenkephalin mRNA in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; Histocytochemistry; In Situ Hybridization; Injections, Intraventricular; Male; N-Methylaspartate; Prosencephalon; Protein Precursors; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P | 1995 |
Muscle NMDA receptors regulate the resting membrane potential through NO-synthase.
Topics: 2-Amino-5-phosphonovalerate; Animals; Diaphragm; Glutamic Acid; Male; Membrane Potentials; Muscle Denervation; Muscles; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Differential action of NMDA antagonists on cholinergic neurotoxicity produced by N-methyl-D-aspartate and quinolinic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Choline O-Acetyltransferase; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Lateral habenular influence on dorsal raphe neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Habenula; Iontophoresis; Male; N-Methylaspartate; Neurons; Raphe Nuclei; Rats; Rats, Wistar | 1996 |
Stimulation of glutamine synthetase activity by excitatory amino acids in astrocyte cultures derived from aged mouse cerebral hemispheres may be associated with non-N-methyl-D-aspartate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; N-Methylaspartate; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1996 |
Nitric oxide responsible for NMDA receptor-evoked inhibition of arachidonic acid incorporation into lipids of brain membrane.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Diphosphate Ribose; Animals; Arachidonic Acid; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Gallic Acid; Inositol 1,4,5-Trisphosphate Receptors; Membrane Lipids; Models, Biological; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-Conotoxins; Peptides; Phosphatidylinositols; Protein Kinases; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tetrodotoxin | 1996 |
CA1 pyramid-pyramid connections in rat hippocampus in vitro: dual intracellular recordings with biocytin filling.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Lysine; Male; Membrane Potentials; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses | 1996 |
The burst-like firing of spinal neurons in rats with peripheral inflammation is reduced by an antagonist of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Inflammation; Iontophoresis; Male; Membrane Potentials; Mesencephalon; N-Methylaspartate; Neurons; Nociceptors; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Synapses | 1996 |
Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Astrocytes; Biological Transport; Biomarkers; Cell Death; Cells, Cultured; Dizocilpine Maleate; Drug Synergism; Enzyme Induction; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; L-Lactate Dehydrogenase; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Sialoglycoproteins; Tumor Necrosis Factor-alpha | 1995 |
Developmental alterations in NMDA receptor-mediated currents in neonatal rat spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glycine Agents; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Postpartum Period; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Tetrodotoxin | 1996 |
Balanced interaction of growth factors and taurine regulate energy metabolism, neuronal survival, and function of cultured mouse cerebellar cells under depolarizing conditions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Culture Media, Serum-Free; Energy Metabolism; Glutamic Acid; Growth Substances; Membrane Potentials; Mice; Mitochondria; N-Methylaspartate; Neurons; Potassium; Taurine | 1996 |
Regulation of dopamine uptake in rat striatal tissue by NMDA receptors as measured using rotating disk electrode voltammetry.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dopamine; Dopamine Antagonists; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Kinetics; Male; N-Methylaspartate; Neostriatum; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Transforming growth factor-beta2 increases NMDA receptor-mediated excitotoxicity in rat cerebral cortical neurons independently of glia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; N-Methylaspartate; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Transforming Growth Factor beta | 1996 |
Non-NMDA receptors transmit cardiopulmonary C fibre input in nucleus tractus solitarii in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Biguanides; Brain Mapping; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Kynurenic Acid; Lung; Male; N-Methylaspartate; Nerve Fibers; Neurons; Pressoreceptors; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Solitary Nucleus; Vagus Nerve | 1996 |
L-deprenyl protects mesencephalic dopamine neurons from glutamate receptor-mediated toxicity in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Death; Culture Media; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Mesencephalon; Monoamine Oxidase Inhibitors; N-Methylaspartate; Neurons; Neuroprotective Agents; Pargyline; Rats; Receptors, Glutamate; Selegiline | 1997 |
NMDA and non-NMDA receptors mediate taste afferent inputs to cortical taste neurons in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Kainic Acid; N-Methylaspartate; Neurons; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Taste | 1995 |
Resetting the biological clock: mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; Animals; Circadian Rhythm; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Gene Expression Regulation; Glutamic Acid; Light; N-Methylaspartate; NADPH Dehydrogenase; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Photic Stimulation; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Suprachiasmatic Nucleus; Time Factors; Transcription, Genetic | 1997 |
Methylcobalamin induces a long-lasting enhancement of the field potential in rat suprachiasmatic nucleus slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; N-Methylaspartate; Optic Nerve; Rats; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Suprachiasmatic Nucleus; Vitamin B 12 | 1996 |
Evidence for N-methyl-D-aspartate receptor-mediated increase in norepinephrine utilization in the prefrontal cortex of unanesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic Agents; Animals; Binding, Competitive; Consciousness; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Norepinephrine; Oxidopamine; Phencyclidine; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sympathomimetics; Tritium | 1997 |
N-methyl-D-aspartate-mediated glutamate toxicity in the developing rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Cell Death; Cyclic GMP; Dextromethorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1997 |
Modulation of the NMDA receptor by cyanide: enhancement of receptor-mediated responses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Cerebellum; Cyanides; Cytoplasmic Granules; Diltiazem; Dizocilpine Maleate; Magnesium; Membrane Potentials; N-Methylaspartate; Nifedipine; Patch-Clamp Techniques; Potassium; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Differential inhibition of NMDA- and naloxone-induced LH release by NMDA receptor antagonist and CRH in ovariectomized estrogen-primed rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Estrogens; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Intraventricular; Luteinizing Hormone; N-Methylaspartate; Naloxone; Narcotic Antagonists; Ovariectomy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid on ischemic brain damage induced by four-vessel occlusion in rats.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Avoidance Learning; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Excitatory Amino Acid Antagonists; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred F344 | 1997 |
Sulphur-containing amino acids modulate noradrenaline release from hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Sulfur; Animals; Calcium; Cobalt; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Magnesium; Male; N-Methylaspartate; Norepinephrine; Organ Culture Techniques; Rats; Rats, Wistar; Sensitivity and Specificity; Stereoisomerism; Tetrodotoxin; Tritium | 1997 |
Effect of glutamate receptor phosphorylation by endogenous protein kinases on electrical activity of isolated postsynaptic densities of rat cortex and hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Cerebral Cortex; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Kainic Acid; Long-Term Potentiation; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Protein Kinases; Quisqualic Acid; Rats; Receptors, Glutamate; Synapses | 1997 |
Long-term potentiation as a mechanism of functional synapse induction in the developing hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Electric Stimulation; Evoked Potentials; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Pyramidal Cells; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1996 |
The effects of an intrathecal NMDA antagonist (AP5) on the behavioral changes induced by colorectal inflammation with turpentine in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Inflammatory Bowel Diseases; Injections, Spinal; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Turpentine | 1997 |
Lead-induced changes in NMDA receptor complex binding: correlations with learning accuracy and with sensitivity to learning impairments caused by MK-801 and NMDA administration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Appetitive Behavior; Autoradiography; Brain; Brain Mapping; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Lead Poisoning; Male; Mental Recall; N-Methylaspartate; Organometallic Compounds; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1997 |
NMDA-receptor regulation of substance P release from primary afferent nociceptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Injections, Spinal; N-Methylaspartate; Neurons, Afferent; Nociceptors; Pain; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Presynaptic; Spinal Cord; Substance P | 1997 |
Selective block of N-methyl-D-aspartic acid (NMDA)-evoked whole-cell currents in mouse cultured spinal neurones by CGP 40116.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Mice; N-Methylaspartate; Spinal Cord | 1997 |
Local synaptic release of glutamate from neurons in the rat hypothalamic arcuate nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium Channels; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamic Acid; Models, Neurological; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1997 |
Activation of N-methyl-D-aspartate receptors regulates basal electrical activity of oxytocin and vasopressin neurons in lactating rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Lactation; Milk Ejection; N-Methylaspartate; Neurons; Oxytocin; Periodicity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex; Supraoptic Nucleus; Vasopressins | 1997 |
Spontaneous bursting activity of dopaminergic neurons in midbrain slices from immature rats: role of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Dopamine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Mesencephalon; N-Methylaspartate; Neurons; Periodicity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Regulation of cerebral microvessels by glutamatergic mechanisms.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microcirculation; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses; Vasoconstriction; Vasodilation | 1997 |
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Animals; Cells, Cultured; Cerebral Cortex; Child; Dizocilpine Maleate; Embryo, Mammalian; Evoked Potentials; Glycine; Homocysteine; Humans; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Responses of Bergmann glia and granule neurons in situ to N-methyl-D-aspartate, norepinephrine, and high potassium.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Animals; Benzoates; Calcium; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Fluorescent Dyes; Glycine; N-Methylaspartate; Neuroglia; Neurons; Norepinephrine; Organic Chemicals; Potassium; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
Role of the dorso-caudal neostriatum in filial imprinting of the domestic chick: a pharmacological and autoradiographical approach focused on the involvement of NMDA-receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Chickens; Densitometry; Deoxyglucose; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorodeoxyglucose F18; Glutamic Acid; Imprinting, Psychological; Injections, Intraventricular; Ligands; N-Methylaspartate; Neostriatum; Receptors, N-Methyl-D-Aspartate | 1997 |
Glutamate-dependent activation of NF-kappaB during mouse cerebellum development.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Antibody Specificity; Cell Nucleus; Cerebellum; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Injections, Intraperitoneal; Mice; Mice, Transgenic; N-Methylaspartate; Neuroprotective Agents; Neurotransmitter Agents; NF-kappa B; Transgenes | 1997 |
Proline-induced potentiation of glutamate transmission.
Topics: 2-Amino-5-phosphonovalerate; Animals; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Proline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1997 |
Uncompetitive NMDA receptor antagonists attenuate NMDA-induced impairment of passive avoidance learning and LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Long-Term Potentiation; Male; Memantine; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Two affinity states of N-methyl-D-aspartate recognition sites: modulation by cations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cations; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Protein Binding; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Tritium | 1997 |
NMDA-mediated facilitation in the echo-delay tuned areas of the auditory cortex of the mustached bat.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Animals; Auditory Cortex; Chiroptera; Echolocation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate | 1997 |
Role of spinal NMDA and AMPA receptors in episodic hypertension in conscious spinal rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Consciousness; Excitatory Amino Acid Antagonists; Heart Rate; Hypertension; Male; N-Methylaspartate; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1997 |
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Electric Stimulation; Endocytosis; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Long-Term Potentiation; Male; Microscopy, Confocal; Microscopy, Fluorescence; Models, Neurological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1997 |
Modulation of intrinsic circuits by serotonin 5-HT3 receptors in developing ferret visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Ferrets; gamma-Aminobutyric Acid; Indoles; Ligands; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyridinium Compounds; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, GABA-A; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Tropisetron; Virulence Factors, Bordetella; Visual Cortex | 1997 |
Response-reinforcement learning is dependent on N-methyl-D-aspartate receptor activation in the nucleus accumbens core.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Appetitive Behavior; Behavior, Animal; Conditioning, Operant; Dopamine; Excitatory Amino Acid Antagonists; Feeding Behavior; Food Deprivation; Locomotion; Male; N-Methylaspartate; Nucleus Accumbens; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology | 1997 |
Conditions for the induction of long-term potentiation and long-term depression by conjunctive pairing in the dentate gyrus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Calcium Chloride; Carbazoles; Dentate Gyrus; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indole Alkaloids; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Neurons; Okadaic Acid; Phosphoric Monoester Hydrolases; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; Ruthenium Red | 1997 |
Distinct effects of MK-801 and (+/-)-2-amino-5-phosphonopentanoic acid on N-methyl-D-aspartate-induced rise of brain temperature in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Body Temperature; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rectum | 1997 |
NMDA-induced response in pyramidal neurons of the rat medial prefrontal cortex slices consists of NMDA and non-NMDA components.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1997 |
Crossed rhythmic synaptic input to motoneurons during selective activation of the contralateral spinal locomotor network.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Chlorides; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Glycine Agents; Locomotion; Motor Neurons; N-Methylaspartate; Neural Inhibition; Periodicity; Rats; Rats, Wistar; Receptors, GABA-A; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine; Synaptic Transmission | 1997 |
Lateral habenula and hippocampus: a complex interaction raphe cells-mediated.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Cell Communication; Electric Stimulation; GABA Antagonists; Habenula; Iontophoresis; Male; N-Methylaspartate; Neurons; Pyramidal Cells; Raphe Nuclei; Rats; Rats, Wistar | 1997 |
Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Arachidonic Acid; Biomarkers; Cells, Cultured; Cerebellum; Dibucaine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flow Cytometry; Fluorescent Dyes; Glycine; Intracellular Membranes; Kynurenic Acid; Membrane Potentials; Mitochondria; N-Methylaspartate; Piperidines; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamine 123; Rhodamines; Sulfonamides | 1997 |
N-methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apoptosis; Calcineurin Inhibitors; Calcium; Cells, Cultured; Cerebellum; Chromatin; Cyclosporine; Excitatory Amino Acid Antagonists; Glutamic Acid; Kinetics; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Manipulations of glutamatergic (N-methyl-D-aspartate receptor) neurotransmission alter the rate of photoperiodically regulated sexual maturation in the male Siberian hamster.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Cricetinae; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Gonadotropin-Releasing Hormone; Male; N-Methylaspartate; Phodopus; Photoperiod; Receptors, N-Methyl-D-Aspartate; Sexual Maturation; Synaptic Transmission; Testis | 1998 |
Glycine increases arterial pressure and augments NMDA-induced pressor responses in the dorsomedial and ventrolateral medulla of cats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cats; Dorsomedial Hypothalamic Nucleus; Drug Synergism; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Glycine; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Ventromedial Hypothalamic Nucleus | 1997 |
Functional organization of rat olfactory bulb glomeruli revealed by optical imaging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Calcium; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Image Processing, Computer-Assisted; Male; N-Methylaspartate; Olfactory Bulb; Organ Culture Techniques; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical; Tetrodotoxin | 1998 |
N-methyl-d-aspartate receptors regulate 5-HT release in the raphe nuclei and frontal cortex of freely moving rats: differential role of 5-HT1A autoreceptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoreceptors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Frontal Lobe; Locomotion; Male; Microdialysis; N-Methylaspartate; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists | 1998 |
Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Calcium; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Fetus; Glycine; Humans; Mice; N-Methylaspartate; Neocortex; Neurites; Neurons; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Steroid 17-alpha-Hydroxylase | 1998 |
Effects of 2-amino-7-phosphonohepatanoic acid, melatonin or NG-nitro-L-arginine on cyanide or N-methyl-D-aspartate-induced neurotoxicity in rat cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radicals; In Vitro Techniques; L-Lactate Dehydrogenase; Melatonin; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Poisons; Potassium Cyanide; Rats | 1998 |
Region-specific and calcium-dependent increase in dialysate choline levels by NMDA.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Brain Chemistry; Calcium; Choline; Choline O-Acetyltransferase; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Microdialysis; N-Methylaspartate; Neostriatum; Neurons; Neurotoxins; Prefrontal Cortex; Quinacrine; Rats; Rats, Wistar | 1998 |
Suppression of sprouting: An early function of NMDA receptors in the absence of AMPA/kainate receptor activity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Cells, Cultured; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Magnesium; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Qa-SNARE Proteins; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Tetrodotoxin; Xenopus | 1998 |
Effects of intraseptal infusions of N-methyl-D-aspartate receptor ligands on memory in an object recognition task in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Exploratory Behavior; Infusions, Parenteral; Ligands; Male; Memory; N-Methylaspartate; Pattern Recognition, Visual; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Septal Nuclei | 1998 |
Neurodegeneration induced by reversed microdialysis of NMDA; a quantitative model for excitotoxicity in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Drug Combinations; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Magnesium; Male; Microdialysis; N-Methylaspartate; Necrosis; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Somatosensory Cortex | 1998 |
Synaptically evoked dendritic action potentials in rat neocortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dendrites; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Iontophoresis; Male; Motor Cortex; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium Channels; Somatosensory Cortex; Tetrodotoxin | 1998 |
Extracellular K+ induces locomotor-like patterns in the rat spinal cord in vitro: comparison with NMDA or 5-HT induced activity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Excitatory Amino Acid Agonists; Locomotion; N-Methylaspartate; Patch-Clamp Techniques; Periodicity; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spinal Cord; Synaptic Transmission | 1998 |
Chlormethiazole anticonvulsive efficacy diminished by N-methyl-D-aspartate but not kainate in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Chlormethiazole; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
Presynaptic 5-HT3 receptors evoke an excitatory response in dorsal vagal preganglionic neurones in anaesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Biguanides; Cadmium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ganglia, Autonomic; Iontophoresis; Magnesium; Male; Membrane Potentials; Motor Neurons; N-Methylaspartate; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Vagus Nerve | 1998 |
Effects of D-AP5 and NMDA microiontophoresis on associative learning in the barrel cortex of awake rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Cerebral Cortex; Conditioning, Psychological; Electromyography; Evoked Potentials; Iontophoresis; Long-Term Potentiation; Male; Memory; Microelectrodes; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vibrissae | 1998 |
Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclopropanes; Dipeptides; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Receptors, Metabotropic Glutamate | 1998 |
Intraseptal infusions of a low dose of AP5, a NMDA receptor antagonist, improves memory in an object recognition task in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Locomotion; Male; Memory; Microinjections; N-Methylaspartate; Psychomotor Performance; Rats; Rats, Wistar; Septal Nuclei | 1998 |
pH modulation of Ca2+ responses and a Ca2+-dependent K+ channel in cultured rat hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Fetus; Hippocampus; Hydrogen-Ion Concentration; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Methylamines; N-Methylaspartate; Neurons; Nifedipine; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar | 1998 |
Variability of AMPA and NMDA receptor mediated responses in CA1 pyramidal cells of young rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1998 |
Chronic dosing with 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, modulates NMDA inhibition of muscarinic-coupled PI hydrolysis in rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; In Vitro Techniques; Inositol; Kynurenic Acid; Male; Muscarinic Agonists; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
Evidence that excitatory amino acid receptors within the temporomandibular joint region are involved in the reflex activation of the jaw muscles.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Brain Stem; Dose-Response Relationship, Drug; Electromyography; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Jaw; Kainic Acid; Lidocaine; Male; Masseter Muscle; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Trigeminal Nerve | 1998 |
Experience-dependent changes in the importance of N-methyl-D-aspartate (NMDA) receptors for visual transmission in superior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Darkness; Gene Expression Regulation, Developmental; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Superior Colliculi; Visual Perception | 1998 |
Serotonergic modulation of the responses to excitatory amino acids of rat dorsal horn neurons in vitro: implications for somatosensory transmission.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; N-Methylaspartate; Neurons; Rats; Sensation; Serotonin; Serotonin Receptor Agonists; Spinal Cord; Synaptic Transmission | 1998 |
Association between the low threshold calcium spike and activation of NMDA receptors in guinea-pig substantia nigra pars compacta neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Differential Threshold; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guinea Pigs; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1998 |
Excitability changes in freeze-induced neocortical microgyria.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Brain; Cerebral Cortex; Electric Stimulation; Epilepsy; Freezing; Functional Laterality; Humans; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley | 1998 |
Spinal inputs from lateral columns to reticulospinal neurons in lampreys.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Brain Stem; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Isotonic Solutions; Lampreys; Locomotion; Magnesium; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Ringer's Solution; Spinal Cord; Synaptic Transmission | 1998 |
Duration of NMDA-dependent synaptic potentiation in piriform cortex in vivo is increased after epileptiform bursting.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; N-Methylaspartate; Neural Inhibition; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Reaction Time; Synapses; Theta Rhythm | 1998 |
Mossy fibre innervation is not required for the development of kainic acid toxicity in organotypic hippocampal slice cultures.
Topics: Animals; Cell Death; Cell Survival; Hippocampus; In Vitro Techniques; Kainic Acid; Microelectrodes; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Pathways; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Time Factors; Valine | 1998 |
Sustained exposure to a glycine receptor partial agonist differentially alters NMDA receptor agonist and antagonist potencies in cultured spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Agonists; Gene Expression; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spinal Cord | 1998 |
Cloning of a brain N-methyl-D-aspartate- and D, L-epsilon-2-amino-4-propyl-5-phosphono-3-pentanoic acid (CGP 39653)-binding protein.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Molecular Sequence Data; N-Methylaspartate; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
N-methyl-D-aspartate induces neurogranin/RC3 oxidation in rat brain slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Calmodulin-Binding Proteins; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutathione; Glutathione Disulfide; In Vitro Techniques; N-Methylaspartate; Nerve Tissue Proteins; Neurogranin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroso Compounds; omega-N-Methylarginine; Oxidation-Reduction; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione | 1999 |
NMDA receptor activation modulates evoked release of substance P from rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Capsaicin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1998 |
Gonadal and age-related influences on NMDA-induced growth hormone secretion in male rats.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Growth Hormone; Growth Hormone-Releasing Hormone; Male; N-Methylaspartate; Orchiectomy; Periodicity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium Glutamate; Testis; Testosterone | 1999 |
Effects of the competitive N-methyl-D-aspartate antagonist CGP 37849 and its ethylester CGP 39551 on N-methyl-D-aspartate-evoked whole-cell currents in cultured spinal neurones and on vestibular stimulation-induced seizures in EL mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Avoidance Learning; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Postural Balance; Receptors, N-Methyl-D-Aspartate; Seizures; Spinal Cord; Vestibule, Labyrinth | 1998 |
NMDA antagonist displays anticonvulsant effect via NO synthesis inhibition in penicillin-treated rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Electrochemistry; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Indazoles; Male; Microelectrodes; N-Methylaspartate; Nitric Oxide; Nitroarginine; Penicillins; Rats; Rats, Wistar | 1998 |
Low resting potential and postnatal upregulation of NMDA receptors may cause Cajal-Retzius cell death.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine Triphosphate; Aging; Animals; Cell Death; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Immunohistochemistry; In Vitro Techniques; Meglumine; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Piperazines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Up-Regulation | 1999 |
Activity-dependent metaplasticity of inhibitory and excitatory synaptic transmission in the lamprey spinal cord locomotor network.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Analysis of Variance; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Interneurons; Lampreys; Male; Motor Neurons; N-Methylaspartate; Neuronal Plasticity; Neurotransmitter Agents; Patch-Clamp Techniques; Serotonin; Serotonin Agents; Spinal Cord; Substance P; Synaptic Transmission | 1999 |
Regulation of vasopressin release by ionotropic glutamate receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Hypothalamo-Hypophyseal System; Kainic Acid; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 1998 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
NMDA-dependent currents in granule cells of the dentate gyrus contribute to induction but not permanence of kindling.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; N-Methylaspartate; Patch-Clamp Techniques; Perforant Pathway; Rats; Rats, Sprague-Dawley; Seizures; Synapses; Time | 1999 |
NMDA receptor characterization and subunit expression in rat cultured mesencephalic neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Gene Expression; Gene Expression Regulation, Developmental; Glycine; Memantine; Mesencephalon; N-Methylaspartate; Neurons; Nitrendipine; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA Splicing; RNA, Messenger | 1999 |
Long-term suppression of synaptic transmission by tetanization of a single pyramidal cell in the mouse hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Phosphinic Acids; Propanolamines; Pyramidal Cells; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Increase in vasopressin concentration and cardiodepressant activity in the blood dialysates after NMDA and hypertonic saline administration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine Vasopressin; Blood Physiological Phenomena; Dialysis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart; Male; N-Methylaspartate; Osmolar Concentration; Quinoxalines; Rats; Rats, Inbred BUF; Rats, Wistar; Saline Solution, Hypertonic | 1998 |
Cardiovascular responses to microinjections of excitatory amino acids into the area postrema of the rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Cerebral Ventricles; Cycloleucine; Decerebrate State; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Tachycardia; Urethane | 1999 |
Acute N-methyl-D,L-aspartate administration stimulates the luteinizing hormone releasing hormone pulse generator in the ovine fetus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Feedback; Female; Fetal Blood; Fetus; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Infusions, Intravenous; Luteinizing Hormone; N-Methylaspartate; Pituitary Gland; Pregnancy; Prolactin; Sheep; Triptorelin Pamoate | 1999 |
Properties of NMDA receptors in rat spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Magnesium; Male; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Visual experience alters the molecular profile of NMDA-receptor-mediated sensory transmission.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dark Adaptation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neurons, Afferent; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synaptic Transmission; Visual Pathways | 1999 |
Modulation of striatal acetylcholine concentrations by NMDA and the competitive NMDA receptor-antagonist AP-5: an in vivo microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Binding, Competitive; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microdialysis; N-Methylaspartate; Neurons; Osmolar Concentration; Perfusion; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
A 'long-term-potentiation-like' facilitation of hippocampal synaptic transmission induced by the nootropic nefiracetam.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Bungarotoxins; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Indoles; Isoquinolines; Kainic Acid; Long-Term Potentiation; Maleimides; Mecamylamine; N-Methylaspartate; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidinones; Rats; Receptors, Nicotinic; Sulfonamides; Synaptic Transmission | 1999 |
Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Growth Factors; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; Retina | 1999 |
Potentiation and depression following stimulus interruption in young rat hippocampi.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Nifedipine; Rats; Rats, Sprague-Dawley; Reference Values | 1999 |
Activation of NMDA receptors in the suprachiasmatic nucleus produces light-like phase shifts of the circadian clock in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain Chemistry; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Lighting; Male; Mesocricetus; Microinjections; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus; Synaptic Transmission | 1999 |
Tolerance to a suprathreshold dose of L-Dopa in MPTP mice: effects of glutamate antagonists.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2-Amino-5-phosphonovalerate; Animals; Antiparkinson Agents; Differential Threshold; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Sexual Behavior, Animal | 1999 |
Differential roles of ionotropic glutamate receptors in canine medullary inspiratory neurons of the ventral respiratory group.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dogs; Excitatory Amino Acid Antagonists; Female; Inhalation; Male; Medulla Oblongata; Membrane Potentials; Microinjections; N-Methylaspartate; Neurons; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Modulation of the mesolimbic dopamine system by glutamate: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Binding, Competitive; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Homovanillic Acid; Limbic System; Male; Microdialysis; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 1999 |
Involvement of NMDA and non-NMDA receptors in transmission of spinal visceral nociception in cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Excitatory Amino Acid Agonists; Female; Kainic Acid; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Splanchnic Nerves; Viscera | 1999 |
Short-term block of Na+/K+-ATPase in neuro-glial cell cultures of cerebellum induces glutamate dependent damage of granule cells.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Binding, Competitive; Calcium; Cells, Cultured; Cerebellum; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium; N-Methylaspartate; Neuroglia; Ouabain; Rats; Rats, Wistar; Rhodamine 123; Sodium-Potassium-Exchanging ATPase; Xanthenes | 1999 |
Effects of lesions to the glutamatergic afferents to the nucleus accumbens in the modulation of reactivity to spatial and non-spatial novelty in mice.
Topics: Afferent Pathways; Amygdala; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Hippocampus; Ibotenic Acid; Injections; Limbic System; Mice; Models, Neurological; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Spatial Behavior; Valine | 1999 |
NMDA receptor-mediated control of GABA release from neurointermediate lobes of female and male rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Estradiol; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Ovariectomy; Pituitary Gland, Posterior; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1999 |
Multiple and opposing roles of cholinergic transmission in the main olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Bicuculline; Calcium; Carbachol; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Kinetics; Magnesium; Mecamylamine; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Receptors, GABA-A; Receptors, Nicotinic; Synapses | 1999 |
Substrate turnover by transporters curtails synaptic glutamate transients.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Benzothiadiazines; Cells, Cultured; Evoked Potentials; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neuroglia; Neurons; Oocytes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Xenopus laevis | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Involvement of peripheral NMDA and non-NMDA receptors in development of persistent firing of spinal wide-dynamic-range neurons induced by subcutaneous bee venom injection in the cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bee Venoms; Cats; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Subcutaneous; Male; N-Methylaspartate; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1999 |
Physiological evidence for ionotropic and metabotropic glutamate receptors in rat taste cells.
Topics: 2-Amino-5-phosphonovalerate; 8-Bromo Cyclic Adenosine Monophosphate; Aminobutyrates; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Taste Buds | 1999 |
Stimulation of NMDA and AMPA receptors in the rat nucleus basalis of Meynert affects sleep.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Nucleus of Meynert; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Quinoxalines; Rats; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sleep; Sleep Stages; Wakefulness | 1999 |
Chemical LTD in the CA1 field of the hippocampus from young and mature rats.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Analysis of Variance; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Organ Culture Techniques; Rats; Rats, Wistar; Signal Transduction; Stimulation, Chemical | 1999 |
3-Hydroxykynurenine potentiates quinolinate but not NMDA toxicity in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Benzenesulfonates; Corpus Striatum; Drug Synergism; Electron Transport Complex IV; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Kynurenine; Male; Motor Activity; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1999 |
Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calmodulin; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression; Hippocampus; Ion Channel Gating; N-Methylaspartate; Phosphorylation; Pyramidal Cells; Rats | 2000 |
Participation of NMDA and kainate receptors of paraventricular nucleus in cardiovascular responses to glutamate receptor agonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Kainic Acid; Male; Microinjections; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
High pressure enhanced NMDA activity in the striatum and the globus pallidus: relationships with myoclonia and locomotor and motor activity in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Atmospheric Pressure; Corpus Striatum; Excitatory Amino Acid Antagonists; Globus Pallidus; High Pressure Neurological Syndrome; Male; Motor Activity; Myoclonus; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 2000 |
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bicuculline; Calcium; Calcium Channels; Cesium; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Methylmalonic and propionic acids increase the in vitro incorporation of 32P into cytoskeletal proteins from cerebral cortex of young rats through NMDA glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Cytoskeletal Proteins; Glutamic Acid; In Vitro Techniques; Methylmalonic Acid; N-Methylaspartate; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Propionates; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
The gain of the baroreflex bradycardia is reduced by microinjection of NMDA receptor antagonists into the nucleus tractus solitarii of awake rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Bradycardia; Cardiovascular System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 2000 |
Long-lasting depolarizations in mitral cells of the rat olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
Biphasic effects of NMDA on the motility of the rat portal vein.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Piperazines; Portal Vein; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Vasodilator Agents | 2000 |
NMDA receptor-mediated control of protein synthesis at developing synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Electrophoresis, Gel, Two-Dimensional; Glutamic Acid; Isoelectric Point; Molecular Weight; N-Methylaspartate; Peptide Elongation Factor 2; Phosphorylation; Precipitin Tests; Protein Biosynthesis; Proteins; Rats; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Superior Colliculi; Synapses; Synaptosomes; Time Factors | 2000 |
Modulation and function of kynurenic acid in the immature rat brain.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; Animals; Brain; Dextroamphetamine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Microdialysis; Mixed Function Oxygenases; N-Methylaspartate; Neurons; Pyruvates; Rats; Rats, Sprague-Dawley | 1999 |
Identification of subunits contributing to synaptic and extrasynaptic NMDA receptors in Golgi cells of the rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Ethylenediamines; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses | 2000 |
NMDA spikes in basal dendrites of cortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cerebral Cortex; Computer Simulation; Dendrites; Electrophysiology; Evoked Potentials; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Adrenergic Antagonists; Animals; Caffeine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Periodicity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Theophylline; Xanthines | 2000 |
Robust changes of afferent-induced excitation in the rat spinal dorsal horn after conditioning high-frequency stimulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Chlorides; Conditioning, Psychological; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuronal Plasticity; Optics and Photonics; Pain; Posterior Horn Cells; Potassium; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots; Strychnine | 2000 |
N-methyl-D-aspartate enhancement of the glycine response in the rat sacral dorsal commissural neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Chloride Channels; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kinetics; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Spinal Cord | 2000 |
Participation of low-threshold calcium spikes in excitatory synaptic transmission in guinea pig medial frontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Frontal Lobe; Guinea Pigs; In Vitro Techniques; Lidocaine; Membrane Potentials; N-Methylaspartate; Potassium Acetate; Pyramidal Cells; Synaptic Transmission | 2000 |
Acute decrease in net glutamate uptake during energy deprivation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Brain Ischemia; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidines; Quinoxalines; Rats | 2000 |
Motor coordination without action potentials in the mammalian spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biological Clocks; Calcium; Gap Junctions; In Vitro Techniques; Interneurons; Motor Activity; Motor Neurons; Motor Skills; N-Methylaspartate; Nerve Net; Periodicity; Rats; Serotonin; Spinal Cord; Stimulation, Chemical; Tetrodotoxin | 2000 |
Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 2000 |
Rapid dendritic remodeling in the developing retina: dependence on neurotransmission and reciprocal regulation by Rac and Rho.
Topics: 2-Amino-5-phosphonovalerate; Animals; Chick Embryo; Dendrites; Excitatory Amino Acid Antagonists; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Retina; Retinal Ganglion Cells; rho GTP-Binding Proteins; Synaptic Transmission; Tetrodotoxin; Transfection | 2000 |
Calcium influx through NMDA receptors directly evokes GABA release in olfactory bulb granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cadmium; Calcium; Calcium Channels; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Virulence Factors, Bordetella | 2000 |
Cerebral cortical muscarinic cholinergic and N-methyl-D-aspartate receptors mediate increase in cortical blood flow elicited by chemical stimulation of periaqueductal gray matter.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Scopolamine; Stimulation, Chemical; Vasodilation; Vasodilator Agents | 2000 |
The regulatory connection between the activity of granule cell NMDA receptors and dendritic differentiation of cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Calcium; Cell Count; Cell Differentiation; Cells, Cultured; Dendrites; Excitatory Amino Acid Antagonists; Glycine; Intracellular Fluid; N-Methylaspartate; Nitric Oxide; Purkinje Cells; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission | 2000 |
Guanine nucleotides block agonist-driven 45Ca2+ influx in chick embryo retinal explants.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Calcium Radioisotopes; Chick Embryo; Excitatory Amino Acid Antagonists; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Monophosphate; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Thionucleotides | 2000 |
Nitric oxide mediates depressor responses by activation of N-methyl-D-aspartate receptors in the nucleus tractus solitarius of cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 2000 |
Postsynaptic origin of N-methyl-D-aspartate-induced slow currents in substantia gelatinosa neurons: an in vitro voltage-clamp study in adult rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substantia Gelatinosa | 2000 |
Glutamatergic regulation of gonadotropin releasing hormone mRNA levels during development in the mouse.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Gonadotropin-Releasing Hormone; Male; Mice; Mice, Inbred C3H; N-Methylaspartate; Neurons; Prosencephalon; RNA, Messenger | 2000 |
Brain-derived neurotrophic factor increases activity of NR2B-containing N-methyl-D-aspartate receptors in excised patches from hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Brain-Derived Neurotrophic Factor; Cell Membrane; Cells, Cultured; Excitatory Amino Acid Antagonists; Guanosine Triphosphate; Hippocampus; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission | 2000 |
Apparent association of MK-801-sensitive ion channels with L-S-nitrosocysteine recognition sites in the hindlimb vasculature of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cysteine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hindlimb; Ion Channels; Male; N-Methylaspartate; Nitroso Compounds; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Vascular Resistance | 2000 |
Reducing conditions significantly attenuate the neuroprotective efficacy of competitive, but not other NMDA receptor antagonists in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dithionitrobenzoic Acid; Dithiothreitol; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Ischemic Attack, Transient; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine | 2000 |
Interferon-alpha inhibits long-term potentiation and unmasks a long-term depression in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Genistein; Glutamic Acid; Hippocampus; Immunologic Factors; In Vitro Techniques; Interferon-alpha; Long-Term Potentiation; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Pyramidal Cells; Rats; Receptors, GABA-A; Synapses | 2000 |
Impairment of the Ca2+-permeable AMPA/kainate receptors by lead exposure in organotypic rat hippocampal slice cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Animals, Suckling; Biological Transport; Calcium; Cobalt; Glutamic Acid; Hippocampus; Lead; N-Methylaspartate; Organ Culture Techniques; Permeability; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 2000 |
NiCl2 and amiloride induce spreading depression in guinea pig hippocampal slices.
Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cortical Spreading Depression; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nickel; Valine | 2000 |
Dendritic glutamate-induced bursting in prefrontal pyramidal cells: role of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Glutamic Acid; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Dopaminergic substantia nigra neurons express functional nmda receptors in postnatal rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Age Factors; Animals; Cell Separation; Dopamine; Excitatory Amino Acid Antagonists; Fluorescent Dyes; In Vitro Techniques; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stilbamidines; Substantia Nigra | 2001 |
NMDA-responsible, APV-insensitive receptor in cultured human astrocytes.
Topics: Astrocytes; Calcium; Cells, Cultured; Glial Fibrillary Acidic Protein; Glycine; GTP-Binding Proteins; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
The effect of N-acetyl-L-aspartic acid dilithium salt on dopamine release and synthesis in the rat striatum in vivo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Rats; Rats, Wistar; Time Factors | 2001 |
Regulatory role of nitric oxide over hippocampal 5-HT release in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Indazoles; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Serotonin | 2001 |
NMDA-evoked calcium transients and currents in the suprachiasmatic nucleus: gating by the circadian system.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Calcium; Circadian Rhythm; Darkness; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; GABA Antagonists; gamma-Aminobutyric Acid; Lighting; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus; Tetrodotoxin | 2001 |
Glutamate does not play a major role in controlling bone growth.
Topics: 2-Amino-5-phosphonovalerate; Alveolar Bone Loss; Amino Acid Transport System X-AG; Animals; Animals, Newborn; ATP-Binding Cassette Transporters; Biological Transport; Bone Diseases, Metabolic; Bone Remodeling; Bone Resorption; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Femur; Glutamic Acid; Glycine; Humerus; Mandible; Mice; Mice, Knockout; Models, Animal; N-Methylaspartate; Osteoblasts; Osteoclasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
Electrophysiological characterization of "giant" cells in stratum radiatum of the CA3 hippocampal region.
Topics: 2-Amino-5-phosphonovalerate; 3,3'-Diaminobenzidine; Action Potentials; Animals; Axons; Bicuculline; Calcium; Cesium; Chlorides; Choline; Cyclopropanes; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Immunoenzyme Techniques; Microscopy, Video; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2001 |
Bidirectional modulation of basal forebrain N-methyl-D-aspartate receptor function differentially affects visual attention but not visual discrimination performance.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Attention; Basal Nucleus of Meynert; Cerebral Cortex; Cholinergic Fibers; Cues; Discrimination Learning; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; N-Methylaspartate; Neural Pathways; Pattern Recognition, Visual; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
Differential effects of NMDA antagonists microinjections into the nucleus reticularis pontis caudalis on seizures induced by pentylenetetrazol in the rat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Pentylenetetrazole; Pons; Rats; Rats, Wistar; Reticular Formation; Seizures | 2001 |
MAP2 phosphorylation and visual plasticity in Xenopus.
Topics: Aging; Animals; Dendrites; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Glutamic Acid; Immunoblotting; Microtubule-Associated Proteins; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Valine; Vision, Binocular; Visual Pathways; Xenopus laevis | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Can voltammetry measure nitrogen monoxide (NO) and/or nitrites?
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Carbon; Carbon Fiber; Electrophysiology; Enzyme Inhibitors; Epinephrine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylaspartate; Neostriatum; Neurochemistry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Rats; Rats, Wistar | 2001 |
Biphasic modulation of NMDA-induced responses in pyramidal cells of the medial prefrontal cortex by Y-931, a potential atypical antipsychotic drug.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Phencyclidine; Piperazines; Prefrontal Cortex; Pyramidal Cells; Rats | 2001 |
Delayed postnatal development of NMDA receptor function in medium-sized neurons of the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
NMDA antagonists in the superior colliculus prevent developmental plasticity but not visual transmission or map compression.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Mapping; Cricetinae; Electrophysiologic Techniques, Cardiac; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Mesocricetus; N-Methylaspartate; Neuronal Plasticity; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Visual Fields; Visual Pathways; Visual Perception | 2001 |
Electrical stimuli patterned after the theta-rhythm induce multiple forms of LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium Channel Blockers; Calcium Channels; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; N-Methylaspartate; Neuronal Plasticity; Nifedipine; Organ Culture Techniques; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Theta Rhythm | 2001 |
Glomerulus-specific synchronization of mitral cells in the olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Periodicity; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell | 2001 |
Absence of evidence is not evidence of absence. Redundancy blocks determination of cause and effect.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Bone Resorption; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Osteoblasts; Osteogenesis; Receptors, N-Methyl-D-Aspartate | 2001 |
Visualization of mPer1 transcription in vitro: NMDA induces a rapid phase shift of mPer1 gene in cultured SCN.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Cycle Proteins; Circadian Rhythm; Culture Techniques; Cycloheximide; Excitatory Amino Acid Antagonists; Gene Expression; Image Processing, Computer-Assisted; Light; Mice; Mice, Transgenic; N-Methylaspartate; Nuclear Proteins; Period Circadian Proteins; Protein Synthesis Inhibitors; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus; Time Factors; Transcription, Genetic | 2001 |
NMDA-mediated increase in renal sympathetic nerve discharge within the PVN: role of nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Kidney; Microinjections; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2001 |
In vivo effects of intracortical administration of NMDA and metabotropic glutamate receptors antagonists on neocortical long-term potentiation and conditioned taste aversion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Benzoates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Male; Microinjections; N-Methylaspartate; Neocortex; Piperazines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Taste | 2002 |
Activation of neuronal N-methyl-D-aspartate receptor channels by lipid emulsions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Cells, Cultured; Cerebral Cortex; Drug Carriers; Fat Emulsions, Intravenous; GABA Antagonists; Ion Channels; Membrane Potentials; Mice; Mice, Inbred BALB C; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Receptors, N-Methyl-D-Aspartate | 2002 |
Calcium signaling at single mossy fiber presynaptic terminals in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Calcium Signaling; Coloring Agents; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Indoles; Mossy Fibers, Hippocampal; N-Methylaspartate; Organ Culture Techniques; Potassium Channel Blockers; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Ryanodine; Thapsigargin | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
N-methyl-D-aspartate-induced long-term depression is associated with a decrease in postsynaptic protein kinase C substrate phosphorylation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calmodulin-Binding Proteins; Down-Regulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GAP-43 Protein; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neural Inhibition; Neurogranin; Neuronal Plasticity; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2002 |
Glutamate mediated responses in isolated trachea preparations from control and ovalbumin sensitized guinea-pigs.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; N-Methylaspartate; Ovalbumin; Receptors, Glutamate; Trachea | 2002 |
Distinct NMDA receptors provide differential modes of transmission at mossy fiber-interneuron synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Chlorides; Cyclopropanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Mossy Fibers, Hippocampal; N-Methylaspartate; Patch-Clamp Techniques; Phenols; Piperidines; Polyamines; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2002 |
The NMDA type glutamate receptors expressed by primary rat osteoblasts have the same electrophysiological characteristics as neuronal receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Femur; Glycine; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Osteoblasts; Patch-Clamp Techniques; Perfusion; Rats; Receptors, N-Methyl-D-Aspartate | 2002 |
Adenosine acting on A1 receptors protects NO-triggered rebound potentiation and LTP in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Nitric Oxide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 2002 |
Receptor-activated calcium signals in tangentially migrating cortical cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Calcium; Calcium Signaling; Cell Movement; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA-A Receptor Agonists; Kainic Acid; Male; Muscimol; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Tetrodotoxin | 2002 |
Contributions from rostral medullary nuclei to coordination of swallowing and breathing in awake goats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Consciousness; Deglutition; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Goats; Kynurenic Acid; Medulla Oblongata; Microinjections; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Respiratory Mechanics | 2002 |
The hypotensive action of rilmenidine is dependent on functional N-methyl-D-aspartate receptor in the rostral ventrolateral medulla of conscious spontaneously hypertensive rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Oxazoles; Rats; Rats, Inbred SHR; Receptors, N-Methyl-D-Aspartate; Rilmenidine | 2002 |
NMDA receptor-dependent CREB activation in survival of cerebellar granule cells during in vivo and in vitro development.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellar Cortex; Colforsin; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2002 |
High frequency stimulation-induced dendritic calcium waves in rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Benzoates; Calcium; Calcium Signaling; Dendrites; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glycine; Hippocampus; In Vitro Techniques; Lidocaine; Male; Microscopy, Confocal; N-Methylaspartate; Neurons; Organic Chemicals; Rats; Rats, Wistar | 2002 |
Glutamatergic and serotonergic mechanisms in the dorsal facial area for common carotid artery blood flow control in the cat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Blood Flow Velocity; Blood Pressure; Carotid Artery, Common; Cats; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Glutamates; Glutamic Acid; Heart Rate; Ketanserin; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, AMPA; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Evidence against the presence of NMDA receptors at a central glutamatergic synapse in leeches.
Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Central Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kynurenic Acid; Leeches; Motor Neurons; N-Methylaspartate; Neurons, Afferent; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex; Synapses; Synaptic Transmission | 2002 |
Effects of intra-accumbens focal administrations of glutamate antagonists on object recognition memory in mice.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Mapping; Discrimination Learning; Dose-Response Relationship, Drug; Exploratory Behavior; Form Perception; Male; Mental Recall; Mice; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Quinoxalines | 2003 |
Excitatory amino acid receptors of the electrosensory system: the NR1/NR2B N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Cells, Cultured; Conserved Sequence; DNA, Complementary; Electric Fish; Electric Organ; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Kidney; Molecular Sequence Data; N-Methylaspartate; Piperidines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Transfection | 2003 |
Functional NMDA receptor channels generated by NMDAR2B gene transfer in rat cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Immunohistochemistry; Infections; Luminescent Proteins; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, N-Methyl-D-Aspartate; Sindbis Virus; Valine | 2003 |
Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Laminectomy; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Urethra | 2003 |
How does prolonged caloric restriction ameliorate age-related impairment of long-term potentiation in the hippocampus?
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Arachidonic Acid; Calcium; Calcium Signaling; Caloric Restriction; Docosahexaenoic Acids; Excitatory Amino Acid Antagonists; Fatty Acids, Unsaturated; Food Deprivation; Hippocampus; Long-Term Potentiation; Male; Membrane Lipids; N-Methylaspartate; Neural Pathways; Neurons; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2003 |
Stimulation of luteinizing hormone secretion by N-methyl-D,L-aspartic acid in the adult male guinea-pig: incomplete blockade by gonadotropin-releasing hormone receptor antagonism.
Topics: Animals; Gonadotropin-Releasing Hormone; Guinea Pigs; Luteinizing Hormone; Male; N-Methylaspartate; Receptors, LHRH; Valine | 2003 |
Functional NMDA receptor subtype 2B is expressed in astrocytes after ischemia in vivo and anoxia in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Axotomy; Brain Ischemia; Calcium; Cell Hypoxia; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Male; N-Methylaspartate; Neurons; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2003 |
Serotonin type II receptor activation facilitates synaptic plasticity via N-methyl-D-aspartate-mediated mechanism in the rat basolateral amygdala.
Topics: Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indophenol; Ketanserin; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Synaptic Transmission; Time Factors; Valine | 2003 |
Transduction of light in the suprachiasmatic nucleus: evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin.
Topics: Animals; Autoradiography; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Light; Male; Melatonin; Microinjections; N-Methylaspartate; Nuclear Proteins; Pineal Gland; Quinoxalines; Radioimmunoassay; RNA, Messenger; Suprachiasmatic Nucleus; Valine | 2003 |
The role of ionotropic receptors of glutaminic acid in cardiovascular system. A. The influence of ionotropic receptor NMDA agonist - 1R,3R-ACPD and antagonist - DL-AP7 on the systemic pressure in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Chlorisondamine; Cycloleucine; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2003 |
Involvement of N-methyl-D-aspartate receptors in post-hypoxic depression of the dorsomedial medulla in cats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Gas Analysis; Blood Pressure; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heart Rate; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spinal Nerves | 2003 |
Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gallic Acid; Guanidines; Indazoles; Injections, Intraperitoneal; Kynurenic Acid; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2003 |
State-dependent processing of sensory stimuli by thalamic reticular neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Iontophoresis; Microelectrodes; N-Methylaspartate; Neural Inhibition; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Thalamus; Vibrissae | 2003 |
Cooperativity between activation of metabotropic glutamate receptors and NMDA receptors in the induction of LTP in hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Boron Compounds; Calcium; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Male; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
MAC reduction after intrathecal coadministration of GABA(A) agonist and glutamate antagonist in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Inhalation; Animals; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Agonists; Imidazoles; Injections, Spinal; Male; Methyl Ethers; Muscimol; N-Methylaspartate; Pain; Pulmonary Alveoli; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sevoflurane | 2003 |
Effects of intrathecal glutamatergic drugs on locomotion. II. NMDA and AP-5 in intact and late spinal cats.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Cats; Decerebrate State; Electric Stimulation; Electromyography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Spinal; Locomotion; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Reflex; Yohimbine | 2003 |
Characterization of spontaneous synaptic transmission in rat medial vestibular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzodiazepines; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Glycine Agents; In Vitro Techniques; Kinetics; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Strychnine; Synaptic Transmission; Vestibular Nuclei | 2003 |
Evidence for a glutamatergic modulation of the cholinergic function in the human enteric nervous system via NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aged; Colon, Ascending; Colon, Sigmoid; Enteric Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Immunohistochemistry; In Vitro Techniques; Kynurenic Acid; Male; Muscle, Smooth; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate | 2003 |
Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity.
Topics: Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Electrophysiology; Embryo, Mammalian; Homocysteine; Hyperhomocysteinemia; N-Methylaspartate; Neocortex; Nerve Net; Neural Inhibition; Rats; Rats, Wistar; Valine | 2004 |
Spike train timing-dependent associative modification of hippocampal CA3 recurrent synapses by mossy fibers.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Animals, Newborn; Chromones; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Models, Neurological; Mossy Fibers, Hippocampal; N-Methylaspartate; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Time Factors | 2004 |
Contributions of NMDA receptors to network recruitment and rhythm generation in spinal cord cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Local; Animals; Apamin; Bicuculline; Cells, Cultured; Drug Interactions; Electric Stimulation; Electrodes; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Tetrodotoxin | 2004 |
Regulatory role of nitric oxide over extracellular taurine in the hippocampus of freely moving rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Hippocampus; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar; Taurine | 2004 |
A proportional but slower NMDA potentiation follows AMPA potentiation in LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transfection; Valine; Visual Cortex | 2004 |
Effects of NMDA receptor-related agonists on learning and memory impairment in olfactory bulbectomized mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Cycloserine; Disease Models, Animal; Dizocilpine Maleate; Drug Therapy, Combination; Injections, Intraventricular; Male; Memory Disorders; Mice; N-Methylaspartate; Olfactory Bulb; Piperidines; Receptors, N-Methyl-D-Aspartate; Spermidine; Time Factors | 2004 |
Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Central Nervous System Stimulants; Dopamine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synapses; Time Factors; Transferrin; Ventral Tegmental Area | 2004 |
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium | 2004 |
Input- and subunit-specific AMPA receptor trafficking underlying long-term potentiation at hippocampal CA3 synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Count; Cell Line; Cricetinae; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Luminescent Proteins; Models, Neurological; Mossy Fibers, Hippocampal; N-Methylaspartate; Protein Subunits; Protein Transport; Pyramidal Cells; Rats; Receptors, AMPA; Sindbis Virus; Synapses; Synaptic Transmission; Transfection | 2004 |
Blockade of presynaptic adenosine A1 receptor responses by nitric oxide and superoxide in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine Deaminase; Animals; Baclofen; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neural Inhibition; Nitric Oxide; Nitric Oxide Donors; Oxidants; Penicillamine; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Superoxides; Time Factors; Xanthine | 2004 |
A molecular technique for detecting the liberation of intracellular zinc in cultured neurons.
Topics: Animals; Cadmium; Cells, Cultured; Cerebral Cortex; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Genes, Reporter; Intracellular Space; Luciferases; Models, Neurological; Molecular Probe Techniques; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor MTF-1; Transcription Factors; Valine; Zinc | 2004 |
Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rats.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Long-Term Potentiation; N-Methylaspartate; Nervous System Physiological Phenomena; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Valine | 2004 |
[Relation between adenosine A1 receptor and NMDA receptor on synaptic transmission in dentate gyrus of hippocampus].
Topics: 2-Amino-5-phosphonovalerate; Adenosine A1 Receptor Antagonists; Animals; Dentate Gyrus; Long-Term Potentiation; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Xanthines | 2004 |
Role of N-methyl-D-aspartate receptors in gastric mucosal blood flow induced by histamine.
Topics: Acids; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspartic Acid; Cimetidine; Drug Interactions; Gastric Mucosa; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Immunohistochemistry; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Time Factors; Tripelennamine; Valine; Yohimbine | 2004 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Phenols; Picrotoxin; Piperidines; Protein Subunits; Pyrrolidines; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; N-Methylaspartate; Pyrazoles; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thermodynamics; Tritium | 2004 |
Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Animals; Baculoviridae; Biophysics; Brain; Cells, Cultured; Chromatography, Gel; Dendritic Spines; Discs Large Homolog 1 Protein; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Genetic Vectors; Guanylate Kinases; Humans; Immunohistochemistry; In Vitro Techniques; Insecta; Intracellular Signaling Peptides and Proteins; Lentivirus; Long-Term Potentiation; Membrane Proteins; Mice; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Energy-Filtering Transmission Electron; Mutagenesis; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Receptors, AMPA; Recombinant Fusion Proteins; RNA, Antisense; RNA, Small Interfering; Sequence Alignment; Synapses; Synaptic Transmission; Time Factors; Transfection; Valine | 2004 |
Pregnenolone sulfate enhances long-term potentiation in CA1 in rat hippocampus slices through the modulation of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Pregnenolone; Rats; Receptors, N-Methyl-D-Aspartate | 2004 |
Putative NMDA receptors in Hydra: a biochemical and functional study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Cell Membrane; Concanavalin A; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Glutathione; Glycine; Hydra; Kynurenic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2004 |
GABAergic transmission in the rat paraventricular nucleus of the hypothalamus is suppressed by corticosterone and stress.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corticosterone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Synaptic Transmission; Time Factors | 2005 |
GluR- and TrkB-mediated maturation of GABA receptor function during the period of eye opening.
Topics: Age Factors; Animals; Animals, Newborn; Blotting, Northern; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Embryo, Mammalian; Eye; GABA Agonists; Gene Expression Regulation, Developmental; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; Receptor, trkB; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superior Colliculi; Synapses; Synaptic Transmission; Valine; Zolpidem | 2005 |
Calmodulin-dependent kinase kinase/calmodulin kinase I activity gates extracellular-regulated kinase-dependent long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzimidazoles; Butadienes; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Excitatory Amino Acid Antagonists; Hippocampus; Isoquinolines; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mutation, Missense; N-Methylaspartate; Naphthalimides; Neurons; Nitriles; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; ras-GRF1; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins | 2005 |
Carotid sinus nerve section abolishes NMDA evoked respiratory effects in anaesthetised rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Blood Pressure; Carotid Sinus; Denervation; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Pulmonary Ventilation; Rats; Rats, Wistar; Respiration; Tidal Volume; Time Factors; Vagotomy | 2005 |
Distinct roles of glycinergic and GABAergic inhibition in coordinating locomotor-like rhythms in the neonatal mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Motor Activity; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Picrotoxin; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine | 2005 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescence Resonance Energy Transfer; Gene Expression; Glutamic Acid; Glycine; Hippocampus; Humans; Insecta; Luminescent Proteins; Microscopy, Confocal; Molecular Biology; Mutagenesis, Site-Directed; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Quinoxalines; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors; Transfection | 2005 |
Diminished neuronal activity increases neuron-neuron connectivity underlying silent synapse formation and the rapid conversion of silent to functional synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Count; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Isoenzymes; Ketamine; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Statistics, Nonparametric; Synapses; Synaptic Transmission; Synaptophysin; Tetrodotoxin; Time Factors | 2005 |
Kinetics and subunit composition of NMDA receptors in respiratory-related neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Northern; Brain Stem; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Respiration; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Valine | 2005 |
Critical period for activity-dependent elimination of corticospinal synapses in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Tracts; Rats; Rats, Wistar; Synapses | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
Hypothalamic release of nitric oxide and interaction with amino acid neurotransmitters in chronically uraemic rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Castration; Enzyme Inhibitors; Hypothalamus; Male; Microdialysis; N-Methylaspartate; Nephrectomy; Neurons; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Uremia | 2005 |
Hippocalcin-deficient mice display a defect in cAMP response element-binding protein activation associated with impaired spatial and associative memory.
Topics: Animals; Association Learning; Avoidance Learning; Behavior, Animal; Blotting, Western; Brain; Cadmium Chloride; Calcium Channel Blockers; Calcium-Binding Proteins; Choice Behavior; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Discrimination Learning; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavonoids; Hippocalcin; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Knockout; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Nimodipine; Phosphorylation; Potassium Chloride; Psychomotor Performance; Reaction Time; Rotarod Performance Test; Spatial Behavior; Valine | 2005 |
A noncanonical release of GABA and glutamate modulates neuronal migration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Bicuculline; Bromodeoxyuridine; Cell Movement; Dideoxynucleosides; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Immunohistochemistry; In Vitro Techniques; Mice; Mice, Mutant Strains; Mice, Transgenic; Microtubule-Associated Proteins; Munc18 Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2005 |
BDNF-induced facilitation of afferent-evoked responses in lamina II neurons is reduced after neonatal spinal cord contusion injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lamin Type B; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Valine | 2005 |
Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Dendritic Spines; Diagnostic Imaging; Dose-Response Relationship, Radiation; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Lasers; Membrane Potentials; Models, Neurological; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2005 |
Rap2-JNK removes synaptic AMPA receptors during depotentiation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Long-Term Synaptic Depression; Magnesium; Models, Neurological; Mutagenesis; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; rap GTP-Binding Proteins; Rats; Receptors, AMPA; Recombinant Proteins; Synaptic Transmission; Time Factors; Transfection; Valine | 2005 |
Plasticity-specific phosphorylation of CaMKII, MAP-kinases and CREB during late-LTP in rat hippocampal slices in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; In Vitro Techniques; Long-Term Potentiation; Male; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Phosphorylation; Rats; Rats, Wistar; Statistics, Nonparametric; Time Factors | 2005 |
Effects of glutamate transporter and receptor ligands on neuronal glutamate uptake.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ligands; N-Methylaspartate; Naphthalenes; Neurons; Neuroprotective Agents; Oxepins; Rats; Rats, Wistar; Receptors, Glutamate; Tritium; Valine | 2005 |
Frequency-dependent impairment of hippocampal LTP from NMDA receptors with reduced calcium permeability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Integrases; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Effects of agonists and antagonists of NMDA and ACh receptors on plasticity of bat auditory system elicited by fear conditioning.
Topics: Acetylcholine; Acoustic Stimulation; Action Potentials; Animals; Atropine; Auditory Cortex; Auditory Pathways; Chiroptera; Cholinergic Agonists; Cholinergic Antagonists; Drug Interactions; Electric Stimulation; Fear; Inferior Colliculi; N-Methylaspartate; Neuronal Plasticity; Time Factors; Valine | 2005 |
Role of AMPA receptor desensitization and the side effects of a DMSO vehicle on reticulospinal EPSPs and locomotor activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Benzothiadiazines; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Lampreys; Motor Activity; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Neurons; Receptors, AMPA; Spinal Cord; Synapses; Valine | 2005 |
An NMDA receptor/nitric oxide cascade is involved in cerebellar LTD but is not localized to the parallel fiber terminal.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Baclofen; Benzoates; Cadmium Chloride; Cerebellum; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Imidazoles; In Vitro Techniques; Long-Term Potentiation; Magnesium; Models, Neurological; N-Methylaspartate; Nerve Fibers; Nerve Tissue Proteins; Nitric Oxide; Nitroarginine; Phosphinic Acids; Propanolamines; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 2005 |
Is NMDA receptor activation essential for the production of locomotor-like activity in the neonatal rat spinal cord?
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Animals, Newborn; Brain Stem; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Edrophonium; Electric Conductivity; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Membrane Potentials; Motor Activity; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Spinal Cord | 2005 |
Effects of brain-derived neurotrophic factor (BDNF) on activity mediated by NMDA receptors in rat spinal cord cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Local; Animals; Antibodies; Brain-Derived Neurotrophic Factor; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neural Inhibition; Neurons; Organ Culture Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin; Valine | 2005 |
The influence of NMDA receptor agonist and antagonist on morphine state-dependent memory of passive avoidance in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Memory; Mental Recall; Mice; Morphine; N-Methylaspartate; Narcotics; Receptors, N-Methyl-D-Aspartate | 2005 |
The antiepileptic activity of JSTX-3 is mediated by N-methyl-D-aspartate receptors in human hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adolescent; Adult; Anticonvulsants; Child; Electrophysiology; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heterocyclic Compounds; Hippocampus; Humans; In Vitro Techniques; Magnesium; Male; Middle Aged; N-Methylaspartate; Neurons; Polyamines; Receptors, N-Methyl-D-Aspartate | 2005 |
Depression of extra-cellular GABA and increase of NMDA-induced nitric oxide following acute intra-nuclear administration of alcohol in the cerebellar nuclei of the rat.
Topics: Animals; Central Nervous System Depressants; Cerebellar Nuclei; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Agonists; gamma-Aminobutyric Acid; Indazoles; Injections, Intraventricular; Male; Microdialysis; N-Methylaspartate; Nipecotic Acids; Nitric Oxide; Quinoxalines; Rats; Rats, Wistar; Tiagabine; Valine | 2005 |
Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antibodies; Blotting, Western; Brain-Derived Neurotrophic Factor; Carrier Proteins; Cells, Cultured; Cortactin; Depsipeptides; Disks Large Homolog 4 Protein; Drug Interactions; Dual-Specificity Phosphatases; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; Homer Scaffolding Proteins; Hydrogen Peroxide; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Models, Biological; Mutagenesis; Mutation; N-Methylaspartate; Neurons; Phosphoprotein Phosphatases; Pyrimidines; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; src Homology Domains; Synapses; Time Factors; Transfection; Vesicular Glutamate Transport Protein 1 | 2005 |
Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Analysis of Variance; Animals; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Gene Expression Regulation; In Situ Hybridization; Lasers; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdissection; N-Methylaspartate; Nerve Tissue Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fyn; RNA, Messenger | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Substitution; Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hippocampus; Humans; Ionomycin; Kidney; Models, Molecular; Mutation, Missense; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Point Mutation; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Isoforms; Protein Processing, Post-Translational; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Synapses; Transfection | 2006 |
Tunicamycin decreases the probability of single-channel openings for N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Probability; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tunicamycin | 2006 |
Effect of NMDA antagonists on the death of cerebellar granule neurons at different ages.
Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; Carbachol; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cholinergic Agonists; Dizocilpine Maleate; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2006 |
NMDA-induced preconditioning attenuates synaptic plasticity in the rat hippocampus.
Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Neurons; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Valine; Xanthines | 2006 |
cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Bacterial Proteins; Blotting, Western; Calcineurin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dendrites; Disks Large Homolog 4 Protein; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Long-Term Synaptic Depression; Luminescent Proteins; Male; Membrane Proteins; Mutagenesis; N-Methylaspartate; Neurons; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Time Factors; Transfection; Valine | 2006 |
Pharmacologically induced calcium oscillations protect neurons from increases in cytosolic calcium after trauma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Signaling; Cytosol; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Antagonists; Gene Expression Regulation; N-Methylaspartate; Neurons; Nimodipine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Thiazoles; Thiazolidines | 2006 |
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Topics: Age Factors; Animals; Biomarkers; Calpain; Dipeptides; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gene Expression Regulation, Developmental; Glucose; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Membrane Proteins; N-Methylaspartate; Neurons; Oxygen; Phenols; Piperidines; Propidium; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrin; Valine | 2006 |
Estrogen modulates the spinal N-methyl-D-aspartic acid-mediated pelvic nerve-to-urethra reflex plasticity in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Estrogens; Female; Glutamic Acid; N-Methylaspartate; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Urethra | 2006 |
Subpopulation of dorsal horn neurons displays enhanced N-methyl-D-aspartate receptor function after chronic morphine exposure.
Topics: 2-Amino-5-phosphonovalerate; Animals; Magnesium; Morphine; N-Methylaspartate; Naloxone; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
Effect of thiopental sodium on N-methyl-D-aspartate-gated currents.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Modulators; Ion Channel Gating; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thiopental | 2006 |
Rapid phosphorylation of histone H2A.X following ionotropic glutamate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; Dizocilpine Maleate; DNA Repair Enzymes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Fluorescent Antibody Technique; Gamma Rays; Gene Expression; Histones; Hydrogen Peroxide; MRE11 Homologue Protein; N-Methylaspartate; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2006 |
Regulation of NMDA receptor trafficking and function by striatal-enriched tyrosine phosphatase (STEP).
Topics: 2-Amino-5-phosphonovalerate; Animals; Biotinylation; Blotting, Western; Calcium; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Humans; Immunoprecipitation; N-Methylaspartate; Protein Subunits; Protein Transport; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; src-Family Kinases; Transfection | 2006 |
Interaction between glutamate and GABA systems in the integration of sympathetic outflow by the paraventricular nucleus of the hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2006 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
Lack of interaction between NMDA and cholecystokinin-2 receptor-mediated neurotransmission in the dorsolateral periaqueductal gray in the regulation of rat defensive behaviors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gastrointestinal Agents; Male; Maze Learning; N-Methylaspartate; Periaqueductal Gray; Quinazolinones; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Signal Transduction; Tetragastrin | 2006 |
Involvement of dorsolateral periaqueductal gray N-methyl-D-aspartic acid glutamate receptors in the regulation of risk assessment and inhibitory avoidance behaviors in the rat elevated T-maze.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Anxiety; Ethosuximide; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Hippocampus; Male; Microinjections; N-Methylaspartate; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Risk-Taking | 2006 |
Non-vagal apnea evoked by intra-common carotid artery injection of N-methyl-D-aspartic acid (NMDA) in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Apnea; Blood Pressure; Carotid Sinus; Denervation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intra-Arterial; Male; N-Methylaspartate; Rats; Rats, Wistar; Respiration; Vagotomy; Vagus Nerve | 2006 |
Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines.
Topics: Actins; Animals; Animals, Newborn; Cell Survival; Central Nervous System Depressants; Dendritic Spines; Disks Large Homolog 4 Protein; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocrateaceae; Homeostasis; Hypoglycemic Agents; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Confocal; N-Methylaspartate; Neurons; Palmitates; Rats; Synapsins; Valine | 2006 |
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bumetanide; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycolates; Ion Channels; Mice; Mice, Inbred C57BL; N-Methylaspartate; Necrosis; Neurons; Neurotoxins; Nitrobenzoates; Patch-Clamp Techniques; Phloretin; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Quinine; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Somatosensory Cortex; Tetrodotoxin | 2007 |
Methamphetamine exposure antagonizes N-methyl-D-aspartate receptor-mediated neurotoxicity in organotypic hippocampal slice cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Binding, Competitive; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Male; Methamphetamine; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2007 |
The relaxing effect of perivascular tissue on porcine retinal arterioles in vitro is mimicked by N-methyl-D-aspartate and is blocked by prostaglandin synthesis inhibition.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 2-Amino-5-phosphonovalerate; Animals; Arterioles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; N-Methylaspartate; Prostaglandin Antagonists; Retina; Retinal Vessels; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2008 |
The responsiveness of the rat intergeniculate leaflet neurons to glutamatergic agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Geniculate Bodies; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium Glutamate; Suprachiasmatic Nucleus | 2007 |
Presynaptic modulation by somatostatin in the neostriatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Somatostatin; Valine | 2008 |
The role of NMDA receptors in regulating group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex.
Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2008 |
Neuroadaptive changes in the mesocortical glutamatergic system during chronic nicotine self-administration and after extinction in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electrochemistry; Excitatory Amino Acid Agents; Extinction, Psychological; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Rats; Rats, Inbred Lew; Self Administration; Ventral Tegmental Area | 2008 |
N-methyl-D-aspartic acid causes relaxation of porcine retinal arterioles through an adenosine receptor-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine Triphosphate; Animals; Arterioles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hydrolysis; Muscle, Smooth, Vascular; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Retinal Artery; Swine; Theophylline; Vasodilation | 2008 |
Acute anal stretch inhibits NMDA-dependent pelvic-urethra reflex potentiation via spinal GABAergic inhibition in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anal Canal; Anesthesia; Animals; Bicuculline; Electric Stimulation; Electromyography; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gallamine Triethiodide; gamma-Aminobutyric Acid; N-Methylaspartate; Neural Inhibition; Neuromuscular Nondepolarizing Agents; Pelvis; Rats; Rats, Wistar; Reflex; Spinal Cord; Urethra; Urination | 2008 |
High potassium induces taurine release by osmosensitive and osmoresistant mechanisms in the rat hippocampus in vivo.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Hippocampus; Hypertonic Solutions; Male; Microdialysis; N-Methylaspartate; Potassium Chloride; Rats; Rats, Sprague-Dawley; Taurine; Valine; Water-Electrolyte Balance | 2009 |
Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microscopy, Electron, Scanning; N-Methylaspartate; Potassium Chloride; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium; Valine | 2008 |
Modulation of ethanol state-dependent learning by dorsal hippocampal NMDA receptors in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Dizocilpine Maleate; Ethanol; Hippocampus; Learning; Male; Memory; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2008 |
Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cycloheximide; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D5; Time Factors; Ventral Tegmental Area | 2008 |
Developmental switch in requirement for PKA RIIbeta in NMDA-receptor-dependent synaptic plasticity at Schaffer collateral to CA1 pyramidal cell synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Valine | 2009 |
Lack of NMDA-AMPA interaction in antidepressant-like effect of CGP 37849, an antagonist of NMDA receptor, in the forced swim test.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antidepressive Agents; Depressive Disorder; Excitatory Amino Acid Antagonists; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming | 2008 |
Alternating low frequency stimulation of medial septal and commissural fibers induces NMDA-dependent, long-lasting potentiation of hippocampal synapses in urethane-anesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Long-Evans; Scopolamine; Septum of Brain; Synapses; Urethane; Valine | 2009 |
Tegmental pedunculopontine glutamate and GABA-B synapses mediate morphine reward.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Morphine; N-Methylaspartate; Narcotics; Pedunculopontine Tegmental Nucleus; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Glutamate; Reward | 2009 |
Cardiovascular and thermal responses evoked from the periaqueductal grey require neuronal activity in the hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Body Temperature Regulation; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Antagonists; Heart Rate; Hypothalamus; Male; Motor Activity; Muscimol; N-Methylaspartate; Neural Pathways; Paraventricular Hypothalamic Nucleus; Periaqueductal Gray; Quinoxalines; Rats; Rats, Sprague-Dawley | 2009 |
Homeostatic presynaptic suppression of neuronal network bursts.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Green Fluorescent Proteins; Hippocampus; Inhibitory Postsynaptic Potentials; Lidocaine; N-Methylaspartate; Nerve Net; Neurons; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptosomal-Associated Protein 25; Tetrodotoxin; Time Factors; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2009 |
Synaptic and extrasynaptic factors governing glutamatergic retinal waves.
Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Aspartic Acid; Calcium; Dihydro-beta-Erythroidine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; N-Methylaspartate; Neural Inhibition; Nicotinic Antagonists; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2009 |
Peripheral inflammation increased the synaptic expression of NMDA receptors in spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Functional Laterality; Gene Expression Regulation; Inflammation; Isoquinolines; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pain Measurement; Posterior Horn Cells; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Subcellular Fractions; Sulfonamides; Synapses | 2009 |
Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.
Topics: 14-3-3 Proteins; Alanine; Animals; Biotinylation; Cell Line, Transformed; Cells, Cultured; Cerebellum; Dendrites; Excitatory Amino Acid Antagonists; Gene Expression; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Insulin-Like Growth Factor I; Luminescent Proteins; Mice; Mutation; N-Methylaspartate; Neurons; Oncogene Protein v-akt; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Transfection; Valine | 2009 |
Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Cells, Cultured; Dendrites; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Excitatory Amino Acid Agents; Gene Expression Regulation; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; Humans; Indans; Indoles; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Oximes; Subcellular Fractions; Synapses; Synaptic Transmission; Transfection; Ubiquitin; Ubiquitin Thiolesterase | 2009 |
The analgesic action of topical diclofenac may be mediated through peripheral NMDA receptor antagonism.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Biophysics; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Injections, Intramuscular; Isoquinolines; Male; Musculoskeletal Diseases; N-Methylaspartate; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Time Factors | 2009 |
Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors.
Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Valine | 2010 |
Histamine potentiates N-methyl-D-aspartate receptors by interacting with an allosteric site distinct from the polyamine binding site.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Site; Animals; Binding Sites; Calcium; Dizocilpine Maleate; Drug Synergism; Hippocampus; Histamine; In Vitro Techniques; Intracellular Space; Male; Methylhistamines; N-Methylaspartate; Neurons; Norepinephrine; Piperidines; Polyamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermine; Synaptosomes | 2010 |
Assessment of different induction protocols to elicit long-term depression (LTD) in the rat visual cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Geniculate Bodies; Glycine; Long-Term Synaptic Depression; Male; N-Methylaspartate; Pentobarbital; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Synaptic Potentials; Urethane; Visual Cortex; Visual Pathways | 2010 |
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds | 2010 |
Bidirectional synaptic plasticity in response to single or paired pulse activation of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons.
Topics: Animals; Excitatory Postsynaptic Potentials; Inhibitory Postsynaptic Potentials; Male; N-Methylaspartate; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin; Valine; Xenon | 2010 |
Activation of N-methyl-D-aspartate (NMDA) receptors in the dorsal vagal complex lowers glucose production.
Topics: 2-Amino-5-phosphonovalerate; Animals; Gene Knockdown Techniques; Glucose; Glycine; Humans; Kynurenic Acid; Liver; Male; N-Methylaspartate; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vagotomy; Vagus Nerve | 2010 |
The lateral paragigantocellular nucleus modulates parasympathetic cardiac neurons: a mechanism for rapid eye movement sleep-dependent changes in heart rate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Heart; Heart Rate; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medulla Oblongata; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Time Factors; Vagus Nerve; Valine | 2010 |
Adrenergic receptor-mediated disinhibition of mitral cells triggers long-term enhancement of synchronized oscillations in the olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Norepinephrine; Olfactory Bulb; Pyridazines; Quinoxalines; Rats; Receptors, Adrenergic; Valine | 2010 |
Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synaptic Transmission | 2010 |
An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Conditioning, Classical; Cyclopentanes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotine; Phencyclidine; Phenols; Piperazines; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Role of ventral hippocampal NMDA receptors in anxiolytic-like effect of morphine.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Mice; Microinjections; Morphine; Motor Activity; N-Methylaspartate; Narcotics; Receptors, N-Methyl-D-Aspartate | 2010 |
Involvement of central amygdala NMDA receptor mechanism in morphine state-dependent memory retrieval.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Male; Memory; Memory Disorders; Morphine; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2011 |
Developmental maturation of excitation and inhibition balance in principal neurons across four layers of somatosensory cortex.
Topics: Animals; Cerebral Cortex; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Time Factors; Valine | 2011 |
Involvement of the thalamic parafascicular nucleus in mesial temporal lobe epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biophysical Phenomena; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Functional Laterality; GABA-A Receptor Agonists; Hippocampus; Intralaminar Thalamic Nuclei; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Muscimol; N-Methylaspartate; Neurons; Statistics, Nonparametric; Time Factors; Wakefulness | 2010 |
Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biological Clocks; Brain Stem; Cadmium Chloride; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Glycyrrhetinic Acid; Humans; In Vitro Techniques; Larva; Models, Biological; Movement; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Periodicity; Pyridazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming; Xenopus | 2010 |
Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Endocytosis; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Membrane Potentials; Microscopy, Confocal; N-Methylaspartate; Nedd4 Ubiquitin Protein Ligases; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA Interference; Transfection; Ubiquitin-Protein Ligases; Ubiquitination; Valine | 2010 |
Repeated pretreatment of morphine prevents morphine-induced amnesia: A possible involvement for dorsal hippocampal NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Animal; CA1 Region, Hippocampal; Drug Administration Schedule; Excitatory Amino Acid Agonists; Inhibition, Psychological; Male; Microinjections; Morphine; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2011 |
Ketamine inhibits tumor necrosis factor secretion by RAW264.7 murine macrophages stimulated with antibiotic-exposed strains of community-associated, methicillin-resistant Staphylococcus aureus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Bacterial Agents; Cell Line; Daptomycin; Dizocilpine Maleate; Drug Synergism; Ketamine; Macrophage Activation; Macrophages; Methicillin-Resistant Staphylococcus aureus; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Time Factors; Tumor Necrosis Factor-alpha; Vancomycin | 2011 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Blockade of NMDA or NO in the dorsal premammillary nucleus attenuates defensive behaviors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cats; Defense Mechanisms; Excitatory Amino Acid Antagonists; Fear; Freezing Reaction, Cataleptic; Locomotion; Male; Mammillary Bodies; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Statistics, Nonparametric | 2011 |
Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Dihydrotestosterone; Enzyme Activation; Estrogens; Female; GABA Antagonists; Glucose; Gonadotropin-Releasing Hormone; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Ovariectomy; Ribonucleotides; Valine | 2011 |
Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Estrogen Replacement Therapy; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Models, Animal; N-Methylaspartate; Neurotransmitter Agents; Ovariectomy; Pregnanolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Blockade of the NMDA and AMPA/kainate receptors in the dorsal raphe nucleus prevents the 5-HT₃ receptor agonist m-chlorophenylbiguanide-induced suppression of REM sleep in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Sleep; Sleep Deprivation; Sleep, REM | 2011 |
Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway.
Topics: Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Astrocytes; Biotinylation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Immunoprecipitation; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; SNARE Proteins; Somatosensory Cortex; src-Family Kinases; Tyrosine; Valine | 2011 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine | 2012 |
Synaptically driven state transitions in distal dendrites of striatal spiny neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine A2 Receptor Agonists; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Calcium; Calcium Channel Blockers; Corpus Striatum; Dendrites; Dopamine Agents; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mibefradil; Mice; Mice, Transgenic; Microscopy, Confocal; Models, Neurological; N-Methylaspartate; Nerve Net; Neurons; Nickel; Patch-Clamp Techniques; Phenethylamines; Spider Venoms; Synapses; Tetrodotoxin; Time Factors | 2011 |
Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Hippocampus; In Vitro Techniques; Inhalation Exposure; Interleukin-1alpha; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroglia; Neurons; Particulate Matter; Rats; Receptors, AMPA; RNA, Messenger; Tumor Necrosis Factor-alpha; Vehicle Emissions | 2011 |
Ethanol enhances neurosteroidogenesis in hippocampal pyramidal neurons by paradoxical NMDA receptor activation.
Topics: 2-Amino-5-phosphonovalerate; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Analysis of Variance; Animals; Animals, Newborn; Azasteroids; CA1 Region, Hippocampal; Central Nervous System Depressants; Dutasteride; Electric Stimulation; Ethanol; Evoked Potentials; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Long-Term Potentiation; Male; N-Methylaspartate; Neural Inhibition; Neurogenesis; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 2011 |
Activation of cannabinoid CB1 receptors in the central amygdala impairs inhibitory avoidance memory consolidation via NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Arachidonic Acids; Avoidance Learning; Male; Microinjections; N-Methylaspartate; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate | 2011 |
Nicotine-induced anxiogenic-like behaviours of rats in the elevated plus-maze: possible role of NMDA receptors of the central amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anxiety; Male; Maze Learning; N-Methylaspartate; Nicotine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2012 |
Median preoptic nucleus and subfornical organ drive renal sympathetic nerve activity via a glutamatergic mechanism within the paraventricular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Angiotensin II Type 1 Receptor Blockers; Animals; Bicuculline; Blood Pressure; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Heart Rate; Kidney; Losartan; Male; N-Methylaspartate; Neurons; Paraventricular Hypothalamic Nucleus; Preoptic Area; Rats; Rats, Sprague-Dawley; Subfornical Organ; Sympathetic Nervous System | 2012 |
Dopamine-glutamate interplay in the ventral striatum modulates spatial learning in a receptor subtype-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzazepines; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Habituation, Psychophysiologic; Learning; Male; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, Dopamine; Space Perception; Sulpiride | 2012 |
Sex difference in stress-induced enhancement of hippocampal CA1 long-term depression during puberty.
Topics: Adrenalectomy; Androgens; Animals; Animals, Newborn; Aspartic Acid; CA1 Region, Hippocampal; Corticosterone; Dexamethasone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucocorticoids; Glutamic Acid; In Vitro Techniques; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Ovariectomy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sex Characteristics; Statistics, Nonparametric; Stress, Psychological; Synaptosomes; Testosterone; Valine | 2012 |
What a nostril knows: olfactory nerve-evoked AMPA responses increase while NMDA responses decrease at 24-h post-training for lateralized odor preference memory in neonate rat.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Conditioning, Psychological; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Functional Laterality; In Vitro Techniques; Learning; Male; N-Methylaspartate; Nose; Odorants; Olfactory Bulb; Olfactory Nerve; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell; Tetrodotoxin | 2012 |
Enhanced activation of RVLM-projecting PVN neurons in rats with chronic heart failure.
Topics: 2-Amino-5-phosphonovalerate; Animals; Chronic Disease; Coronary Vessels; Electric Stimulation; Electrophysiological Phenomena; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Heart Failure; Ligation; Male; Medulla Oblongata; Midline Thalamic Nuclei; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Osmolar Concentration; Pressoreceptors; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 2012 |
Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Isoproterenol; Long-Term Potentiation; Long-Term Synaptic Depression; Methoxamine; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Photic Stimulation; Propranolol; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Valine; Visual Cortex; Visual Pathways | 2012 |
Endogenous ACh effects on NMDA-induced interictal-like discharges along the septotemporal hippocampal axis of adult rats and their modulation by an early life generalized seizure.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Cholinesterase Inhibitors; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; Muscarinic Antagonists; N-Methylaspartate; Neurons; Pentylenetetrazole; Physostigmine; Rats; Rats, Sprague-Dawley; Seizures; Sex Factors; Valine | 2012 |
Contractile properties and movement behaviour in neonatal rats with axotomy, treated with the NMDA antagonist DAP5.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Axotomy; Behavior, Animal; Excitatory Amino Acid Antagonists; Female; Male; Motor Neurons; Movement; Muscle Contraction; Muscle Denervation; Muscle, Skeletal; N-Methylaspartate; Nerve Crush; Rats, Wistar | 2012 |
Microinjection of NMDA-type glutamate receptor agonist NMDA and antagonist D-AP-5 into the central nucleus of the amygdale alters water intake rather than food intake.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Drinking; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2012 |
Salsolinol facilitates glutamatergic transmission to dopamine neurons in the posterior ventral tegmental area of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Central Nervous System Depressants; Dopaminergic Neurons; Ethanol; Excitatory Amino Acid Antagonists; Isoquinolines; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Synaptic Transmission; Ventral Tegmental Area | 2012 |
Presynaptic NMDA receptor-mediated modulation of excitatory neurotransmission in the mouse dorsal motor nucleus of the vagus.
Topics: Animals; Biophysics; Chlorides; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamates; In Vitro Techniques; Male; Medulla Oblongata; Mice; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Vagus Nerve; Valine; Zinc Compounds | 2012 |
L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Inferior Colliculi; Male; Microinjections; N-Methylaspartate; Nitroarginine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Time Factors | 2012 |
Temporal dependence of cysteine protease activation following excitotoxic hippocampal injury.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calpain; Cell Death; Cell Survival; Cells, Cultured; Cysteine Proteases; Dipeptides; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Immunohistochemistry; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synaptophysin | 2012 |
Muscarinic control of AMPA receptor responsiveness in mouse spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; In Vitro Techniques; Indoles; Mice; Mice, Inbred C57BL; Motor Neurons; Muscarinic Agonists; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, Muscarinic; Spinal Cord | 2012 |
Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Ionophores; Calpain; Cycloheximide; Cysteine Proteinase Inhibitors; Dipeptides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emetine; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Ionomycin; K Cl- Cotransporters; Leupeptins; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyramidal Cells; Rats; Rats, Wistar; Statistics, Nonparametric; Symporters; Valine | 2012 |
Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Amino Acid Motifs; Animals; Animals, Newborn; CA1 Region, Hippocampal; Calcium; Calmodulin; Chelating Agents; Disks Large Homolog 4 Protein; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Luminescent Proteins; Male; MAP Kinase Signaling System; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mutation; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Protein Binding; Protein Conformation; Rats; Receptors, AMPA; Sulfotransferases; Transfection; Valine | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
The balance between receptor recycling and trafficking toward lysosomes determines synaptic strength during long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Arabidopsis Proteins; Biophysics; Carrier Proteins; Cysteine Proteinase Inhibitors; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Green Fluorescent Proteins; GTP-Binding Proteins; Hippocampus; Leupeptins; Long-Term Potentiation; Long-Term Synaptic Depression; Lysosomes; Male; N-Methylaspartate; Neurons; Organ Culture Techniques; Protein Transport; Rats; Rats, Wistar; Receptors, AMPA; Statistics, Nonparametric; Synapses; Transfection | 2012 |
Development of NMDA-induced theta rhythm in hippocampal formation slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Bicuculline; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agents; Hippocampus; In Vitro Techniques; Male; Muscimol; N-Methylaspartate; Rats; Theta Rhythm; Time Factors | 2013 |
Study of the interaction of glutamatergic and nitrergic signalling in conditions of the experimental airways hyperreactivity.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Bronchial Hyperreactivity; Dizocilpine Maleate; Excitatory Amino Acid Agents; Guinea Pigs; Histamine; Male; Muscle, Smooth; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Sodium Glutamate; Trachea | 2013 |
Effects of CA1 glutamatergic systems upon memory impairments in cholestatic rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; CA1 Region, Hippocampal; Cholestasis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Memory; Memory Disorders; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2013 |
Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Citalopram; Cyclopropanes; Imipramine; Immobility Response, Tonic; Male; Mice; Milnacipran; Morpholines; Motor Activity; N-Methylaspartate; Oxazines; Quinoxalines; Reboxetine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2013 |
Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Dopaminergic Neurons; Electrochemistry; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Microinjections; N-Methylaspartate; Nicotine; Nicotinic Agonists; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Self Administration; Ventral Tegmental Area | 2014 |
Superoxide anions in paraventricular nucleus modulate adipose afferent reflex and sympathetic activity in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Adipose Tissue, White; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Cyclic N-Oxides; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Spin Labels; Superoxide Dismutase; Superoxides; Sympathetic Nervous System | 2013 |
NMDA receptor activation antagonizes the NMDA antagonist-induced antianxiety effect in the elevated plus-maze test in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Male; Maze Learning; Mice; N-Methylaspartate; Quinolones; Receptors, N-Methyl-D-Aspartate; Serine | 2013 |
Antidepressant properties of aqueous macerate from Gladiolus dalenii corms.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Fluoxetine; Hindlimb Suspension; Imipramine; Iridaceae; Male; Medicine, African Traditional; Mice; Motor Activity; N-Methylaspartate; Phytotherapy; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming | 2014 |
Involvement of the nucleus accumbens shell glutamatergic system in ACPA-induced impairment of inhibitory avoidance memory consolidation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acids; Avoidance Learning; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Memory; Memory Disorders; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Piperidines; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2014 |
Orphenadrine-induced convulsive status epilepticus in rats responds to the NMDA antagonist dizocilpine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dizocilpine Maleate; Electroencephalography; Hippocampus; Male; N-Methylaspartate; Orphenadrine; Rats; Rats, Wistar; Seizures; Status Epilepticus | 2014 |
A mechanistic study on urine retention in d-amphetamine addicts.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine | 2014 |
N-methyl-D-aspartate receptor agonism and antagonism within the amygdaloid central nucleus suppresses pain affect: differential contribution of the ventrolateral periaqueductal gray.
Topics: Animals; Central Amygdaloid Nucleus; Dose-Response Relationship, Drug; Electroshock; Male; N-Methylaspartate; Narcotic Antagonists; Pain; Pain Perception; Peptide Fragments; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Random Allocation; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reflex; Somatostatin; Valine; Vocalization, Animal | 2014 |
Amygdalar neuronal activity mediates the cardiovascular responses evoked from the dorsolateral periaqueductal gray in conscious rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Arterial Pressure; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; Glutamic Acid; Heart Rate; Male; Microinjections; Muscimol; N-Methylaspartate; Neurons; Periaqueductal Gray; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate | 2015 |
Participation of NMDA receptors in the lateral hypothalamus in gastric erosion induced by cold-water restraint.
Topics: Analysis of Variance; Animals; Cold Temperature; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stomach Ulcer; Valine | 2015 |
Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Valine; Ventral Tegmental Area | 2015 |
The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Learning; CA1 Region, Hippocampal; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Mice; Microinjections; N-Methylaspartate; Piperidines; Pyrazoles; Receptors, N-Methyl-D-Aspartate | 2015 |
Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus.
Topics: Adenosine Triphosphate; Animals; CA1 Region, Hippocampal; Dioxolanes; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Guinea Pigs; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Microtomy; N-Methylaspartate; Neurons; Purines; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Tissue Culture Techniques; Valine | 2015 |
A corticothalamic switch: controlling the thalamus with dynamic synapses.
Topics: Animals; Bacterial Proteins; Central Nervous System Stimulants; Channelrhodopsins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Luminescent Proteins; Mice; Mice, Inbred ICR; Mice, Transgenic; N-Methylaspartate; Neural Pathways; Optogenetics; Picrotoxin; Receptors, Neurotensin; Somatosensory Cortex; Synapses; Thalamus; Valine | 2015 |
A Metabotropic-Like Flux-Independent NMDA Receptor Regulates Ca2+ Exit from Endoplasmic Reticulum and Mitochondrial Membrane Potential in Cultured Astrocytes.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Astrocytes; Benzimidazoles; Calcium; Calcium Channel Blockers; Carbocyanines; Cells, Cultured; Dizocilpine Maleate; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate Receptors; Ions; Kynurenic Acid; Membrane Potential, Mitochondrial; N-Methylaspartate; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Xanthenes | 2015 |
Ethanol attenuates peripheral NMDAR-mediated vascular oxidative stress and pressor response.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Ethanol; Heart Rate; Male; N-Methylaspartate; Oxidative Stress; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2015 |
Distinct effects of ventral tegmental area NMDA and acetylcholine receptor blockade on conditioned reinforcement produced by food-associated cues.
Topics: Animals; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reinforcement, Psychology; Scopolamine; Valine; Ventral Tegmental Area | 2015 |
The role of NMDA receptors of the medial septum and dorsal hippocampus on memory acquisition.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; CA1 Region, Hippocampal; Excitatory Amino Acid Antagonists; Locomotion; Male; Memory; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2016 |
Synaptic Mechanisms Generating Orientation Selectivity in the ON Pathway of the Rabbit Retina.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Choline O-Acetyltransferase; Dendrites; Electric Stimulation; Excitatory Amino Acid Agents; Female; GABA Agents; In Vitro Techniques; Male; N-Methylaspartate; Orientation; Patch-Clamp Techniques; Photic Stimulation; Rabbits; Retina; Retinal Ganglion Cells; Synapses; Visual Pathways | 2016 |
The Level of NMDA Receptor in the Membrane Modulates Amyloid-β Association and Perforation.
Topics: 2-Amino-5-phosphonovalerate; Amyloid beta-Peptides; Animals; Cell Membrane; Cells, Cultured; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; HEK293 Cells; Hippocampus; Humans; Membrane Potentials; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Pregnancy; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate | 2016 |
Experimental Cortical Spreading Depression Induces NMDA Receptor Dependent Potassium Currents in Microglia.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Barium; Cells, Cultured; Cortical Spreading Depression; Enzyme Inhibitors; Female; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; N-Methylaspartate; Potassium; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, N-Methyl-D-Aspartate | 2016 |
Stimulation of the hypothalamic arcuate nucleus increases brown adipose tissue nerve activity via hypothalamic paraventricular and dorsomedial nuclei.
Topics: 2-Amino-5-phosphonovalerate; Adipose Tissue, Brown; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA-A Receptor Agonists; Glutamic Acid; Immunohistochemistry; Male; Microinjections; Muscimol; N-Methylaspartate; Neural Inhibition; Paraventricular Hypothalamic Nucleus; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Stilbamidines; Sympathetic Nervous System; Temperature; Thermogenesis; Vesicular Glutamate Transport Proteins | 2016 |
Interaction between dorsal hippocampal NMDA receptors and lithium on spatial learning consolidation in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; CA1 Region, Hippocampal; Catheters, Indwelling; Dose-Response Relationship, Drug; Lithium Chloride; Male; Memory Consolidation; Memory Disorders; N-Methylaspartate; Neuropsychological Tests; Nootropic Agents; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spatial Learning; Spatial Memory | 2016 |
Interaction between NMDA and CB2 function in the dorsal hippocampus on memory consolidation impairment: an isobologram analysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Excitatory Amino Acid Antagonists; Hippocampus; Indenes; Male; Memory; Memory Consolidation; Memory Disorders; Microinjections; N-Methylaspartate; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, N-Methyl-D-Aspartate | 2017 |
Centrally mediated ejaculatory response via sympathetic outflow in rats: role of N-methyl-D-aspartic acid receptors in paraventricular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Ejaculation; Female; Male; Microinjections; N-Methylaspartate; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sexual Behavior, Animal; Sympathetic Nervous System | 2017 |
Contribution of the basolateral amygdala NMDA and muscarinic receptors in rat's memory retrieval.
Topics: Animals; Basolateral Nuclear Complex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mental Recall; Muscarinic Antagonists; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Scopolamine; Valine | 2017 |
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Algorithms; Animals; Carrier Proteins; Cells, Cultured; Computer Simulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABAergic Neurons; Hippocampus; Long-Term Synaptic Depression; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Peptides; Polymers; Post-Synaptic Density; Receptors, GABA-A; Valine | 2017 |
β-Catenin in the Adult Visual Cortex Regulates NMDA-Receptor Function and Visual Responses.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; beta Catenin; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Parvalbumins; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sensory Deprivation; Synaptic Potentials; Visual Cortex; White Matter | 2018 |
Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties.
Topics: Astrocytes; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioblastoma; Humans; Immunosuppressive Agents; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Nitric Oxide Synthase Type III; RNA, Messenger; Sirolimus; Time Factors; Up-Regulation; Valine | 2017 |
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Citrates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agents; In Vitro Techniques; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine; Vibrissae | 2017 |
NMDARs contribute to the facial stimuli-evoked mossy fiber-granule cell synaptic transmission in vivo in mice.
Topics: Animals; Cerebellar Cortex; Excitatory Amino Acid Antagonists; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Physical Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine; Vibrissae | 2020 |
Glutamate, d-(-)-2-Amino-5-Phosphonopentanoic Acid, and
Topics: 2-Amino-5-phosphonovalerate; Animals; Buffers; Cells, Cultured; Chronic Pain; Glutamic Acid; Humans; Mice; N-Methylaspartate; Neurons; Oocytes; Patch-Clamp Techniques; Primary Cell Culture; Rats; Receptors, Glycine; Recombinant Proteins; Reproducibility of Results; Spinal Cord; Synapses; Synaptic Transmission; Xenopus laevis; Zinc | 2020 |
Evaluating spatial and network properties of NMDA-dependent neuronal connectivity in mixed cortical cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; N-Methylaspartate; Neurons; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2022 |
NMDA receptor blockade in the dorsolateral striatum impairs consolidation but not retrieval of habit memory.
Topics: 2-Amino-5-phosphonovalerate; Animals; Habits; Male; Memory; N-Methylaspartate; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2023 |