2-amino-5-phosphonovalerate has been researched along with ketamine in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (20.00) | 18.7374 |
| 1990's | 49 (65.33) | 18.2507 |
| 2000's | 8 (10.67) | 29.6817 |
| 2010's | 3 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aszodi, A; Crunelli, V; Soltesz, I | 1 |
| Henry, JL; Hong, YG | 1 |
| Henry, JL; Hong, Y | 1 |
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Ivanova, SF; Sanzharovskiĭ, AV; Storozhuk, VM | 1 |
| Chang, FC; Gean, PW | 1 |
| Böhmer, G; Schauer, W; Schmid, K | 1 |
| Daló, NL; Larson, AA | 1 |
| Lipton, P; Lobner, D | 1 |
| Dall'Olio, R; Gandolfi, O; Montanaro, N; Roncada, P | 1 |
| Hablitz, JJ; Lee, WL | 1 |
| Dickenson, AH; Haley, JE; Sullivan, AF | 1 |
| Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA | 1 |
| Chaki, S; Muramatsu, M; Otomo, S; Usuki-Ito, C | 1 |
| Egert, U; Kossel, A; Rauschecker, JP | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Gross, GW; Lucas, JH; Wang, GF | 1 |
| Mohri, T; Suzuki, R; Takadera, T | 1 |
| Mitchell, D; Sher, GD | 1 |
| Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ | 1 |
| Haberly, LB; Hoffman, WH | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| MacDonald, JF; Schneiderman, JH | 1 |
| Ben-Ari, Y; Cherubini, E; Corradetti, R; Gaiarsa, JL | 1 |
| De Prins, E; Marrannes, R; Wauquier, A; Willems, R | 1 |
| Lodge, D; Martin, D | 2 |
| Lees, GJ | 1 |
| de Carolis, AS; Frank, C; Sagratella, S | 1 |
| Aram, JA; Lodge, D | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Mayer, ML; Vyklický, L; Westbrook, GL | 1 |
| Alford, ST; Coan, EJ; Collingridge, GL; Davies, SN; Lester, RA | 1 |
| Boast, CA; Pastor, G | 1 |
| Song, XJ; Zhao, ZQ | 2 |
| Lücke, T; Neugebauer, V; Schaible, HG | 2 |
| Henry, JL; Radhakrishnan, V | 1 |
| Feuerstein, TJ | 1 |
| Pike, NV; Wayman, CP; Wilson, JF | 1 |
| D'Hooge, R; De Deyn, PP; Pei, YQ | 1 |
| Durand, J | 1 |
| Bongrani, S; Dall'Olio, R; Gandolfi, O; Rimondini, R; Valsecchi, B | 1 |
| Scholfield, CN; Yassin, M | 1 |
| Bousquet, P; Feldman, J; Mettauer, B; Monassier, L; Roegel, JC; Tibiriça, E | 1 |
| Grubb, B; Lücke, T; Neugebauer, V; Schaible, HG | 1 |
| Ashida, H; Kawakami, Y | 1 |
| Alford, S; Dubuc, R | 1 |
| Peng, L; Zhao, Z | 1 |
| Chang, FC; Gean, PW; Hung, CR | 1 |
| Azérad, J; Boucher, Y; Pollin, B | 1 |
| Brainard, MS; Feldman, DE; Knudsen, EI | 1 |
| Bures, J; Motaghed-Larijani, Z; Rashidy-Pour, A | 1 |
| Gall, CM; Guthrie, KM; Sullivan, RM; Wilson, DA | 1 |
| Bernardi, G; Grillner, P; Mercuri, NB | 1 |
| Chaplan, SR; Malmberg, AB; Yaksh, TL | 1 |
| Kaila, K; Lamsa, K; Taira, T | 1 |
| Chizh, BA; Cumberbatch, MJ; Headley, PM; Herrero, JF; Stirk, GC | 1 |
| Cabello, P; Contreras, E; Germany, A; González, P; Norris, B | 1 |
| Faber, DS; Pereda, AE; Wolszon, LR | 1 |
| Amabeoku, GJ | 1 |
| Butler, AK; Chesselet, MF; Rougon, G; Uryu, K | 1 |
| Geiger, JD; Haughey, NJ; Holden, CP; Nath, A | 1 |
| Atapour, N; Esteky, H; Fathollahi, Y; Motamedi, F; Salami, M | 1 |
| Dickenson, AH; Rahman, W; Urch, CE | 1 |
| Fathollahi, Y; Salami, M | 1 |
| Stein, EA; Xi, ZX | 1 |
| Geiger, JD; Hochman, S; Moore, A; Nath, A; Song, L | 1 |
| Cissé, Y; Crochet, S; Steriade, M; Timofeev, I | 1 |
| Kiyosue, K; Nakayama, K; Taguchi, T | 1 |
| Bae, YM; Cho, SI; Kim, B; Kim, JG; Kim, SH; Kim, YS; Noh, HJ; Park, SH; Woo, NS | 1 |
| Aguirre, CA; English, BK; Lazar, L; Meals, E; Rayburn, MS; Shapley, RK; Spentzas, T; Walker, BS | 1 |
| Chan, MH; Chen, HH; Liao, PF | 1 |
| Ashkenazi, S; Berent, E; Weizman, A; Yuhas, Y | 1 |
75 other study(ies) available for 2-amino-5-phosphonovalerate and ketamine
| Article | Year |
|---|---|
Detecting changes in neuronal activities induced by N-methyl-D-aspartate receptor blockade using non-linear dynamics techniques.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Evoked Potentials; Geniculate Bodies; In Vitro Techniques; Ketamine; Kinetics; Magnesium; Membrane Potentials; Neurons; Perfusion; Receptors, N-Methyl-D-Aspartate | 1992 |
Glutamate, NMDA and NMDA receptor antagonists: cardiovascular effects of intrathecal administration in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1992 |
NMDA receptor antagonists block cardiovascular responses to intrathecal administration of D-baclofen in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Blood Pressure; Injections, Intravenous; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thoracic Vertebrae | 1992 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
[Role of glutamate intracortical connections in conditioned reflex activity].
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Cerebral Cortex; Conditioning, Classical; Evoked Potentials, Somatosensory; Glutamates; Glutamic Acid; Iontophoresis; Ketamine; Kynurenic Acid; Membrane Potentials; Neurons; Receptors, N-Methyl-D-Aspartate | 1992 |
Ketamine suppresses synchronized discharges in the disinhibited amygdala slice.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Ketamine; Male; Microelectrodes; Neurons; Rats; Rats, Inbred Strains; Synapses | 1991 |
Evidence for an involvement of NMDA and non-NMDA receptors in synaptic excitation of phrenic motoneurons in the rabbit.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glutamine; Ketamine; Microinjections; Motor Neurons; Phrenic Nerve; Quinoxalines; Rabbits; Receptors, N-Methyl-D-Aspartate; Respiration; Spinal Cord; Synapses | 1991 |
Effects of urethane and ketamine on substance P- and excitatory amino acid-induced behavior in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Injections, Spinal; Isomerism; Kainic Acid; Ketamine; Male; Mice; N-Methylaspartate; Quisqualic Acid; Substance P; Urethane | 1990 |
Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cyclazocine; Dizocilpine Maleate; Glutamates; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Ketamine; Kynurenic Acid; Male; Models, Neurological; Phencyclidine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma | 1990 |
NMDA antagonists interact with 5-HT-stimulated phosphatidylinositol metabolism and impair passive avoidance retention in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Brain; Cerebral Cortex; Hippocampus; Ketamine; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retention, Psychology; Serotonin | 1990 |
Effect of APV and ketamine on epileptiform activity in the CA1 and CA3 regions of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Epilepsy; Hippocampus; Ketamine; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Electric Stimulation; Formaldehyde; Ketamine; Neurons; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1990 |
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Differentiation of the active site of minaprine from that of phencyclidine in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Binding Sites; Hippocampus; Ketamine; Male; Membranes; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Potassium Channels; Pyridazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
Effects of NMDA antagonists on developmental plasticity in kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics; Animals; Animals, Newborn; Cats; Cerebral Cortex; Dizocilpine Maleate; Injections; Ketamine; N-Methylaspartate; Neuronal Plasticity; Visual Cortex | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
NMDA antagonists prevent hypothermic injury and death of mammalian spinal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Dizocilpine Maleate; Female; Freezing; Hypothermia, Induced; Ketamine; Mice; N-Methylaspartate; Neurons; Pregnancy; Spinal Cord Injuries | 1990 |
Protection by ethanol of cortical neurons from N-methyl-D-aspartate-induced neurotoxicity is associated with blocking calcium influx.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cerebral Cortex; Ethanol; Female; Ketamine; L-Lactate Dehydrogenase; N-Methylaspartate; Nervous System Diseases; Neurons; Pregnancy; Rats | 1990 |
N-methyl-D-aspartate receptors mediate responses of rat dorsal horn neurones to hindlimb ischemia.
Topics: Animals; Anterior Horn Cells; Hindlimb; Injections, Spinal; Ischemia; Ketamine; Male; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1990 |
Systemic approaches to modifying quinolinic acid striatal lesions in rats.
Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine | 1988 |
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
Excitatory amino acid blockers differentially affect bursting of in vitro hippocampal neurons in two pharmacological models of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Ketamine; Kynurenic Acid; Phencyclidine; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Giant synaptic potentials in immature rat CA3 hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Animals, Newborn; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Ketamine; Membrane Potentials; Phencyclidine; Picrotoxin; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cortical Spreading Depression; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine | 1987 |
Effects of ketamine on the in vivo toxicity of quinolinate and N-methyl-D-aspartate in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia, General; Animals; Aspartic Acid; Drug Interactions; Female; Halothane; Hippocampus; Ketamine; N-Methylaspartate; Pentobarbital; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1987 |
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Alkalosis; Animals; Aspartic Acid; Cerebral Cortex; Epilepsy; In Vitro Techniques; Ketamine; Magnesium Deficiency; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Homocysteine; Iontophoresis; Ketamine; Male; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Valine | 1988 |
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cations, Divalent; Cells, Cultured; Glycine; Hippocampus; Ketamine; Kynurenic Acid; Magnesium; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Zinc | 1988 |
Ketamine blocks an NMDA receptor-mediated component of synaptic transmission in rat hippocampus in a voltage-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; In Vitro Techniques; Ketamine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1988 |
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors | 1987 |
Interaction between substance P and excitatory amino acid receptors in modulation of nociceptive responses of cat spinal dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electric Stimulation; Homocysteine; Ketamine; Kynurenic Acid; Muscles; Neurokinin-1 Receptor Antagonists; Neurons; Nociceptors; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P; Sural Nerve | 1994 |
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Ketamine; Male; Neurons; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
[Ketamine inhibits n-methyl-d-aspartate (NMDA) receptor mediated acetylcholine release from rabbit caudate nucleus slices].
Topics: Acetylcholine; Action Potentials; Amantadine; Animals; Caudate Nucleus; Choline; Dizocilpine Maleate; In Vitro Techniques; Ketamine; Memantine; Rabbits; Receptors, N-Methyl-D-Aspartate; Valine | 1994 |
N-methyl-D-aspartate (NMDA) stimulates release of alpha-MSH from the rat hypothalamus through release of nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; alpha-MSH; Animals; Arginine; Hypothalamus; Ketamine; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Rats; Rats, Wistar | 1994 |
N-methyl-D-aspartate receptors contribute to guanidinosuccinate-induced convulsions in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Drug Interactions; Female; Glutamates; Glutamic Acid; Guanidines; Kainic Acid; Ketamine; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate; Seizures; Succinates | 1993 |
Synaptic excitation triggers oscillations during NMDA receptor activation in rat abducens motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Abducens Nerve; Animals; Dizocilpine Maleate; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Ketamine; Male; Motor Neurons; N-Methylaspartate; Oscillometry; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arthritis, Experimental; Electrophysiology; Hindlimb; Injections, Intravenous; Iontophoresis; Ketamine; Male; Neurons; Physical Stimulation; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Repeated administrations of (-)-deprenyl increase [3H]MK801 binding in rat brain and antagonize the impairment of passive avoidance conditioning induced by N-methyl-D-aspartate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Brain; Cell Membrane; Dextroamphetamine; Dizocilpine Maleate; Hippocampus; In Vitro Techniques; Ketamine; Male; Pargyline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Selegiline; Synaptic Membranes | 1994 |
NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Hypoxia; Dizocilpine Maleate; Evoked Potentials; Female; In Vitro Techniques; Ketamine; N-Methylaspartate; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Prevention by NMDA receptor antagonists of the centrally-evoked increases of cardiac inotropic responses in rabbits.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Electric Stimulation; Glutamates; Glutamic Acid; Ketamine; Kynurenic Acid; Male; Myocardial Contraction; Paraventricular Hypothalamic Nucleus; Rabbits; Receptors, N-Methyl-D-Aspartate | 1994 |
The involvement of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Ankle Joint; Arthritis, Experimental; Chronic Disease; Electrophysiology; Ketamine; Male; Neurons; Pain; Pressure; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Differential effects of NMDA and non-NMDA receptor antagonists on spinal cutaneous vs muscular nociception in the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Iontophoresis; Ketamine; Kynurenic Acid; Muscles; Nerve Fibers; Nociceptors; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Skin Physiological Phenomena; Spinal Cord; Synaptic Transmission | 1993 |
Long-lasting potentiation of field potentials in primary and secondary somatosensory cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Anesthesia; Animals; Anticonvulsants; Cats; Electric Stimulation; Evoked Potentials, Somatosensory; Ketamine; Microelectrodes; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Thalamic Nuclei | 1993 |
Glutamate metabotropic receptor mediated depression of synaptic inputs to lamprey reticulospinal neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Cycloleucine; Electric Stimulation; Electrophysiology; Evoked Potentials; GTP-Binding Proteins; Ketamine; Lampreys; Microelectrodes; N-Methylaspartate; Neurons; Receptors, Glutamate; Reticular Formation; Rhombencephalon; Spinal Cord; Synapses | 1993 |
Glutamate effects on calcium homeostasis in cerebellar granule cells in primary cultures grown under depolarizing and nondepolarizing conditions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Cytosol; Glutamates; Glutamic Acid; Homeostasis; Kainic Acid; Ketamine; Mice; Nerve Tissue Proteins; Neuromuscular Depolarizing Agents; Potassium; Quisqualic Acid | 1993 |
Use-dependent modification of a slow NMDA receptor-mediated synaptic potential in rat amygdalar slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Animals; Bicuculline; Electrophysiology; Epilepsy; Evoked Potentials; In Vitro Techniques; Ketamine; Male; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Microinfusions of excitatory amino acid antagonists into the trigeminal sensory complex antagonize the jaw opening reflex in freely moving rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Dental Pulp; Dipeptides; Electric Stimulation; Electromyography; Histocytochemistry; Jaw; Ketamine; Male; Microinjections; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex; Trigeminal Nerve | 1993 |
Newly learned auditory responses mediated by NMDA receptors in the owl inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Auditory Perception; Birds; Diazepam; Excitatory Amino Acid Antagonists; Inferior Colliculi; Ketamine; Kynurenic Acid; Learning; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Sound Localization; Synaptic Transmission; Visual Perception | 1996 |
Tolerance to ketamine-induced blockade of cortical spreading depression transfers to MK-801 but not to AP5 in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cortical Spreading Depression; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Ketamine; Male; Microinjections; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1995 |
NMDA-receptor modulation of lateral inhibition and c-fos expression in olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; Ketamine; Male; Neural Inhibition; Olfactory Bulb; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1996 |
N-methyl-D-aspartate receptors mediate a slow excitatory postsynaptic potential in the rat midbrain dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Dopamine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketamine; Membrane Potentials; Mesencephalon; Neurons; Picrotoxin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission; Tegmentum Mesencephali; Tetrodotoxin; Time Factors | 1996 |
Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Formaldehyde; Hyperalgesia; Injections, Spinal; Ketamine; Male; Memantine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerves; Touch | 1997 |
Posttetanic excitation mediated by GABA(A) receptors in rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Ethoxzolamide; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Interneurons; Ketamine; Male; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Tetany | 1997 |
Stimulus intensity, cell excitation and the N-methyl-D-aspartate receptor component of sensory responses in the rat spinal cord in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Ketamine; Male; Nociceptors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1997 |
Decrease of tolerance to, and physical dependence on morphine by, glutamate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Ketamine; Male; Mice; Morphine; Morphine Dependence; Pain Measurement; Substance Withdrawal Syndrome | 1997 |
A fast synaptic potential mediated by NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Goldfish; Kainic Acid; Ketamine; Microelectrodes; Neurons; Piperazines; Pons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists; Synapses; Synaptic Transmission | 1997 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
N-methyl-D-aspartate receptor blockade affects polysialylated neural cell adhesion molecule expression and synaptic density during striatal development.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Corpus Striatum; Dizocilpine Maleate; Gene Expression Regulation, Developmental; Ketamine; Microinjections; Neural Cell Adhesion Molecule L1; Neural Cell Adhesion Molecules; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sialic Acids; Synapses | 1999 |
Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.
Topics: 2-Amino-5-phosphonovalerate; Astrocytes; Brain; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Fetus; Gallic Acid; Gene Products, tat; HIV-1; Humans; Inositol 1,4,5-Trisphosphate; Ketamine; Neurons; Neurotoxins; Pertussis Toxin; Quinoxalines; tat Gene Products, Human Immunodeficiency Virus; Thapsigargin; Video Recording; Virulence Factors, Bordetella | 1999 |
Effects of ketamine on synaptic transmission and long-term potentiation in layer II/III of rat visual cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Ketamine; Long-Term Potentiation; Male; Rats; Synaptic Transmission; Visual Cortex | 2000 |
Electrophysiological studies on the role of the NMDA receptor in nociception in the developing rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Ketamine; Male; Nerve Fibers; Nociceptors; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
The role of N-methyl-D-aspartate receptors in synaptic plasticity of rat visual cortex in vitro: effect of sensory experience.
Topics: 2-Amino-5-phosphonovalerate; Animals; Darkness; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Ketamine; Lighting; Long-Term Potentiation; Neuronal Plasticity; Photic Stimulation; Rats; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Visual Cortex | 2001 |
Blockade of ionotropic glutamatergic transmission in the ventral tegmental area reduces heroin reinforcement in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feeding Behavior; Heroin; Injections, Intraventricular; Ketamine; Locomotion; Male; Microinjections; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reinforcement, Psychology; Self Administration; Time Factors; Ventral Tegmental Area | 2002 |
Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Allosteric Regulation; Allosteric Site; Animals; Excitatory Amino Acid Antagonists; Gene Products, tat; Hippocampus; HIV-1; Humans; Ketamine; Kynurenic Acid; Neurons; Patch-Clamp Techniques; Protein Interaction Mapping; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; tat Gene Products, Human Immunodeficiency Virus; Zinc | 2003 |
Synaptic enhancement induced through callosal pathways in cat association cortex.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Agonists; Anesthetics, Intravenous; Animals; Barbiturates; Cats; Corpus Callosum; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Ketamine; Microdialysis; Neocortex; Neural Pathways; Neurons; Receptors, N-Methyl-D-Aspartate; Synapses; Xylazine | 2004 |
Diminished neuronal activity increases neuron-neuron connectivity underlying silent synapse formation and the rapid conversion of silent to functional synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Count; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Isoenzymes; Ketamine; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Statistics, Nonparametric; Synapses; Synaptic Transmission; Synaptophysin; Tetrodotoxin; Time Factors | 2005 |
The vasodilatory effect of ketamine is independent of the N-methyl-D-aspartate receptor: lack of functional N-methyl-D-aspartate receptors in rat mesenteric artery smooth muscle.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Dissociative; Animals; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isometric Contraction; Ketamine; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Splanchnic Circulation; Stereoisomerism; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Ketamine inhibits tumor necrosis factor secretion by RAW264.7 murine macrophages stimulated with antibiotic-exposed strains of community-associated, methicillin-resistant Staphylococcus aureus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Bacterial Agents; Cell Line; Daptomycin; Dizocilpine Maleate; Drug Synergism; Ketamine; Macrophage Activation; Macrophages; Methicillin-Resistant Staphylococcus aureus; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Time Factors; Tumor Necrosis Factor-alpha; Vancomycin | 2011 |
mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Ketamine; Male; Mice; Mice, Nude; Piperidines; Protein Kinase C; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2011 |
Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties.
Topics: Astrocytes; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioblastoma; Humans; Immunosuppressive Agents; Ketamine; MAP Kinase Signaling System; N-Methylaspartate; Nitric Oxide Synthase Type III; RNA, Messenger; Sirolimus; Time Factors; Up-Regulation; Valine | 2017 |