2-amino-5-phosphonovalerate has been researched along with kainic acid in 247 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (23.48) | 18.7374 |
| 1990's | 149 (60.32) | 18.2507 |
| 2000's | 33 (13.36) | 29.6817 |
| 2010's | 7 (2.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anis, NA; Bukownik, R; Eldefrawi, AT; Eldefrawi, ME; Goodnow, RA; Nakanishi, K; Usherwood, PN | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Jensen, TS; Yaksh, TL | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 1 |
| Arellano, RO; Conde-Guerri, B; Matute, C; Miledi, R | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Helm, SW; Henzi, V; MacDermott, AB; Reichling, DB | 1 |
| Di Loreto, S; Florio, T; Scarnati, E | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Weiland, NG | 1 |
| Amano, T; Hishinuma, F; Kuwahara, R; Okabe, N; Ozawa, F; Yamakuni, T | 1 |
| Flavin, MP; Riopelle, RJ; Yang, Y | 1 |
| Dingledine, R; McBain, C | 1 |
| Barnabei, O; Contestabile, A; Migani, P; Virgili, M | 1 |
| Sekiguchi, M; Wada, K; Wenthold, RJ | 1 |
| Kurusu, R; Sakurai, H; Sano, K; Tsuchiya, T; Tsuda, M | 1 |
| Ames, A; Li, YY | 1 |
| De Sarro, A; De Sarro, G; Meldrum, BS; Patel, S | 1 |
| Besser, GM; Costa, A; Forsling, ML; Grossman, A; Hucks, D; Yasin, SA | 1 |
| Wayman, CP; Wilson, JF | 1 |
| Holopainen, I; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Baraban, JM; Blatter, LA; Murphy, TH; Wier, WG | 1 |
| Coghill, RC; Frenk, H; Kellstein, DE; Mao, J; Mayer, DJ | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Bonhaus, DW; McNamara, JO | 1 |
| Gale, K; Miller, LP; Murray, TF; Zhong, P | 1 |
| Chiorri, C; Cordi, AA; Dappen, MS; Monahan, JB; Natalini, B; Pellicciari, R | 1 |
| DiMicco, JA; Soltis, RP | 1 |
| Aizenman, E; Lipton, SA; Sucher, NJ | 1 |
| Klunk, WE; McClure, RJ; Pettegrew, JW | 1 |
| Anderton, PJ; Millar, TJ | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Bandopadhyay, R; de Belleroche, J | 1 |
| Clark, AJ; Hastings, MH; Latimer, M; Stone, TW; Winn, P | 1 |
| Sapru, H; Sundaram, K | 1 |
| Turner, DA; Wheal, HV | 1 |
| Onodera, K; Takeuchi, A | 1 |
| Garcia-Munoz, M; Groves, PM; Young, SJ | 1 |
| Akerman, KE; Holopainen, I; Louve, M | 1 |
| Delrée, P; Lefebvre, PP; Leprince, P; Moonen, G; Rigo, JM; Rogister, B; Weber, T | 1 |
| Simpson, LH; Wheal, HV; Williamson, R | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ | 1 |
| Oja, SS; Saransaari, P | 1 |
| Esguerra, M; Kwon, YH; Sur, M | 1 |
| Coderre, TJ; Melzack, R | 1 |
| Aroniadou, VA; Teyler, TJ | 1 |
| Ohmori, H; Yamaguchi, K | 1 |
| Daló, NL; Larson, AA | 1 |
| McMillian, M; Miller, LG; Schatzki, A | 1 |
| Cline, HT; Tsien, RW | 1 |
| Cowan, A; Larson, AA; Murray, CW | 1 |
| Larson, AA; Sun, XF | 1 |
| Franke, C; Hatt, H; Rosenheimer, JL; Smith, DO; Zufall, F | 1 |
| Kendig, JJ; Woodley, SJ | 1 |
| Arancio, O; MacDermott, AB; Murase, K; Yoshimura, M | 1 |
| Brehm, L; Jørgensen, FS; Krogsgaard-Larsen, P; Madsen, U; Schaumburg, K | 1 |
| Galarraga, E; Kitai, ST; Surmeier, DJ | 1 |
| Urca, G; Urca, R | 1 |
| Khaspekov, LG; Lisý, V; Stastný, F; Viktorov, IV | 1 |
| Kimura, F; Nishigori, A; Tsumoto, T | 1 |
| Hoehn, K; White, TD | 1 |
| Akerman, KE; Holopainen, I | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Fischbach, GD; O'Brien, RJ | 1 |
| Bossut, D; Frenk, H; Mayer, DJ | 1 |
| Christensen, BN; O'Dell, TJ | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| Brugger, F; Olpe, HR; Pozza, MF; Steinmann, MW | 1 |
| Chapman, B; Miller, KD; Stryker, MP | 1 |
| Bowe, MA; Martin, D; Nadler, JV | 1 |
| Miyachi, E; Murakami, M | 1 |
| Bieger, D; Hashim, MA | 1 |
| Dye, J; Heiligenberg, W; Kawasaki, M; Keller, CH | 1 |
| Jacquet, YF; Squires, RF | 1 |
| Jacquet, YF | 1 |
| Lodge, D; Martin, D | 2 |
| Martin, MR | 1 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| Collins, JF; Stone, TW | 1 |
| Ashwood, TJ; Wheal, HV | 2 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Johnson, KM; Jones, SM; Snell, LD | 1 |
| Ballanyi, K; Endres, W; Grafe, P; Serve, G | 1 |
| Cherniack, NS; Mitra, J; Overholt, JL; Prabhakar, NR | 1 |
| Drejer, J; Honoré, T; Schousboe, A | 1 |
| Samanin, R; Vezzani, A; Wu, HQ | 1 |
| Choi, DW; Koh, JY; Peters, S | 1 |
| Hagihara, K; Hata, Y; Sato, H; Tsumoto, T | 1 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Beart, PM; Headley, PM; Nicolopoulos, LS; West, DC | 1 |
| Lason, W; McGinty, JF; Simpson, JN | 1 |
| Kihara, M; Kubo, T | 1 |
| Bockaert, J; Pin, JP; Van-Vliet, BJ | 1 |
| Connick, JH; Stone, TW | 1 |
| Carter, CJ; L'Heureux, R; Scatton, B | 1 |
| Pastuszko, A; Wilson, DF | 1 |
| Nishizaki, T; Okada, Y | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Ben-Ari, Y; Cherubini, E; Neuman, R | 1 |
| Raigorodsky, G; Urca, G | 1 |
| Lovinger, DM; Weight, FF | 1 |
| Lauritzen, M; Nicholson, C; Okada, Y; Rice, ME | 1 |
| Benveniste, H; Diemer, NH; Hansen, AJ; Jørgensen, MB | 1 |
| Ben-Ari, Y; Gho, M | 1 |
| Baud, J; Fagg, GE | 1 |
| Do, KQ; Herrling, PL; Turski, WA | 1 |
| Balm, M; Coyle, JT; Markl, A; Zaczek, R | 1 |
| Evans, RH; Watkins, JC | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 1 |
| Collins, JF; Parks, DA; Schwarcz, R | 1 |
| Collingridge, GL; Kehl, SJ; McLennan, H | 1 |
| Crunelli, V; Forda, S; Kelly, JS | 1 |
| Dvorak, DR; Morgan, IG | 1 |
| Mayer, ML; Westbrook, GL | 1 |
| Czuczwar, SJ; Meldrum, B | 1 |
| Schwarcz, R; Whetsell, WO | 1 |
| Collins, JF; Perkins, MN; Stone, TW | 1 |
| Bernard, C; Wheal, HV | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Mikuni, M; Saitoh, K; Shinno, H; Takahashi, K; Tomita, U; Yamawaki, S | 1 |
| Jonas, P; Sakmann, B; Spruston, N | 1 |
| Dowling, JE; Grant, GB | 1 |
| Balcar, VJ; Killinger, S; Li, Y | 1 |
| Hu, B; Nissen, R; Renaud, LP | 1 |
| Bernard, CL; Wheal, HV | 1 |
| Herrling, PL; Meier, CL | 1 |
| Lemaire, S; Shukla, VK | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Canton, T; Debono, MW; Doble, A; Le Guern, J; Pradier, L | 1 |
| Fukuda, H; Hicks, TP; Kobayashi, T; Nagao, T; Oka, JI | 1 |
| Rigor, BM; Schurr, A | 1 |
| Gordon, FJ; Kiely, JM | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Fagg, GE; Massieu, L; McVey, M; Thedinga, KH | 1 |
| Bading, H; Dudek, H; Greenberg, ME; Lipton, SA; Segal, MM; Sucher, NJ | 1 |
| Croucher, MJ; Patel, DR; Sturt, NJ | 1 |
| Opitz, T; Pidoplichko, VI; Reymann, KG; Shinozaki, H; Wilsch, VW | 1 |
| Lowry, T; Simon, RP; Tanaka, K | 1 |
| Shimosaka, S; Simon, RP; So, YT | 1 |
| Ciani, E; Contestabile, A; Facchinetti, F; Virgili, M | 1 |
| Abercrombie, ED; Keefe, KA; Sved, AF; Zigmond, MJ | 1 |
| D'Hooge, R; De Deyn, PP; Pei, YQ | 1 |
| López-Colomé, AM; Ortega, A; Romo-de-Vivar, M | 1 |
| Akaoka, H; Aston-Jones, G; Buda, M; Charléty, PJ; Chergui, K; Chouvet, G; Saunier, CF | 1 |
| Ben-Ari, Y; Gaiarsa, JL; Zagrean, L | 1 |
| Carlen, PL; Gurevich, N; Pace-Asciak, CR; Reynaud, D; Wu, PH; Zhang, L | 1 |
| Cabrera, RJ; Donoso, AO; Navarro, CE | 1 |
| Ciani, E; Contestabile, A; Guarnieri, T | 1 |
| Galbiati, M; Martini, L; Messi, E; Zanisi, M | 1 |
| Kinney, GG; Kocsis, B; Vertes, RP | 1 |
| Dai, X; Douglas, JR; Jordan, LM; Noga, BR | 1 |
| Lacaille, JC; Vachon, P; Williams, S | 1 |
| Ebner, TJ; Elias, SA; Yae, H | 1 |
| Kessler, JP | 1 |
| Boudouresque, F; Chautard, T; Guillaume, V; Oliver, C | 1 |
| Peng, L; Zhao, Z | 1 |
| Abercrombie, ED; Keefe, KA; Zigmond, MJ | 1 |
| Grillner, S; Schotland, JL | 1 |
| Dingledine, R; McBain, CJ | 1 |
| Larson, AA; Sun, X | 1 |
| Jhamandas, JH; Zidichouski, JA | 1 |
| Chen, B; Kocsis, JD; Pourcho, R; Rand, MN; Waxman, SG | 1 |
| Porter, JP | 1 |
| Auth, F; DeBoer, P; Moor, E; Westerink, BH | 1 |
| Huganir, RL; Moshaver, A; Raymond, LA; Tingley, WG | 1 |
| Dee, MG; Donias, HW; Duva, MA; Stanley, BG; Willett, VL | 1 |
| Iino, M; Isa, T; Itazawa, S; Ozawa, S; Tsuzuki, K | 1 |
| Kent, S; Kernahan, SD; Levine, S | 1 |
| Ramsdell, JS; Xi, D | 1 |
| Feltz, P; Jo, YH; Poisbeau, P; Schlichter, R | 1 |
| Justice, JB; Welch, SM | 1 |
| Graham, SH; Simon, RP; Tanaka, K | 1 |
| Alici, K; Gloveli, T; Heinemann, U; Motine, V; Weber-Luxenburger, G | 1 |
| Ogawa, H; Otawa, S; Takagi, K | 1 |
| Lai, YY; Siegel, JM | 1 |
| Orrego, F; Riquelme, G; Villanueva, S; Wyneken, U | 1 |
| Kawaguchi, K; Simon, RP | 1 |
| Casula, A; Diana, M; Gessa, GL; Lilliu, V; Mereu, G; Musa, A; Vargiu, PF | 1 |
| Fergus, A; Lee, KS | 1 |
| Janáky, R; Jenei, Z; Oja, SS; Saransaari, P; Varga, V | 1 |
| Leibrock, J; Prücher, H; Rautenberg, W | 1 |
| Horikawa, J; Suga, N; Tanahashi, A | 1 |
| Herreras, O; Lerma, J; Rodríguez-Moreno, A | 1 |
| Isa, T; Itazawa, SI; Ozawa, S | 1 |
| Faber, DS; Pereda, AE; Wolszon, LR | 1 |
| Dudek, FE; Patrylo, PR | 1 |
| Czuczwar, SJ; Kleinrok, Z; Pilip, S; Turski, WA; Urbanska, EM | 1 |
| Fowler, CJ; Hedin, H; Jacobsson, SO; Sellström, A | 1 |
| Mifflin, SW; Zhang, J | 1 |
| Cairns, BE; Hu, JW; Sessle, BJ | 1 |
| Gatherer, M; Sundstrom, LE | 1 |
| Higuchi, T; Honda, K; Murata, T; Narita, K; Nishihara, M; Takahashi, M | 1 |
| Badre, SE; Morsette, DJ; Sladek, CD; Swenson, KL | 1 |
| D'Hooge, R; De Deyn, PP; Raes, A; Van Bogaert, PP; Van de Vijver, G | 1 |
| Bhatnagar, T; Chitravanshi, VC; Sapru, HN | 1 |
| Abdrachmanova, G; Palecek, JI; Vlachová, V; Vyklick, L | 1 |
| Goshima, Y; Kawashima, K; Misu, Y; Miyamae, T; Ohshima, E; Shibata, T; Shimizu, M; Suzuki, F | 1 |
| Matsuoka, T; Matsuyama, S; Nishizaki, T; Nomura, T; Shiotani, T; Watabe, S; Yoshii, M | 1 |
| Bongianni, F; Deliagina, TG; Grillner, S | 1 |
| Linden, R; Martins, RA; Rocha, M | 1 |
| Cannon, RC; Chad, JE; Chen, Y; Wheal, HV | 1 |
| Song, XJ; Zhao, ZQ | 1 |
| Ballanyi, K; Kulik, A; Metzger, F; Sendtner, M | 1 |
| Lerma, J; López-García, JC; Rodríguez-Moreno, A | 1 |
| Berkman, K; Gören, MZ; Onat, F | 1 |
| Carlson, GC; Keller, A; Shipley, MT | 1 |
| Abraini, JH; Kriem, B; Rostain, JC | 1 |
| Kullmann, DM; Semyanov, A | 1 |
| Chiu, CT; Fang, KM; Hwang, HM; Lee, YH; Tsai, W; Yang, CM | 1 |
| Behr, J; Heinemann, U; Mody, I | 1 |
| Meador-Woodruff, JH; Ritter, LM; Unis, AS | 1 |
| Bradley, SR; Conn, PJ; Marino, MJ; Wittmann, M | 1 |
| Jiang, L; Kang, J; Nedergaard, M; Xu, J | 1 |
| Canonico, PL; Dianzani, C; Fantozzi, R; Lombardi, G; Miglio, G | 1 |
| Bottazzi, B; Garlanda, C; Hirsch, E; Mantovani, A; Moneta, D; Peri, G; Ravizza, T; Richards, GJ; Vezzani, A | 1 |
| Cepeda, C; Hurst, RS; Levine, MS; Shumate, LW | 1 |
| Isaac, JT; Kidd, FL | 1 |
| Attwell, D; Hamann, M; Marie, H; Rossi, DJ | 1 |
| Soria, JM; Valdeolmillos, M | 1 |
| Bleakman, D; Bortolotto, ZA; Collingridge, GL; Isaac, JT; Lauri, SE; Lodge, D; Nistico, R; Ornstein, PL | 1 |
| André, N; Gillardin, JM; Heulard, I; Verleye, M | 1 |
| Clarke, VR; Collingridge, GL | 1 |
| Kartelija, G; Nedeljkovic, M; Radenovic, L; Selakovic, V; Todorovic, N | 1 |
| Begtrup, M; Bräuner-Osborne, H; Calí, P; Clausen, RP; Egebjerg, J; Greenwood, JR; Hansen, KB; Nielsen, B | 1 |
| Anderson, AE; Johnston, D; Leung, V; Lin, X; Shah, MM | 1 |
| Breustedt, J; Schmitz, D | 1 |
| Henderson, Z; Jones, GA | 1 |
| Beneyto, M; Dean, B; Meador-Woodruff, JH; Scarr, E | 1 |
| Chen, L; Sokabe, M | 1 |
| Coons, S; Ellsworth, K; Johnson, E; Kerrigan, JF; Kim, DY; Lue, LF; Nowak, L; Rekate, H; Rho, JM; St John, PA; Wu, J; Xu, L | 1 |
| Kanno, T; Maruo, K; Maruo, S; Nishizaki, T; Yaguchi, T; Yamamoto, S; Yashiya, S | 1 |
| Terman, GW; Thomson, LM; Zeng, J | 1 |
| Bai, D; Gong, XQ; Zabek, RL | 1 |
| Baram, TZ; Bender, RA; Brewster, AL; Richichi, C; Simeone, TA; Weiss, JH; Yin, HZ; Zha, Q | 1 |
| Campbell, SL; Hablitz, JJ | 1 |
| Margaryan, G; Mattioli, C; Mladinic, M; Nistri, A | 1 |
| Bernard, H; Charpier, S; David, O; Depaulis, A; Deransart, C; Langlois, M; Polack, PO | 1 |
| Bielefeld, L; Froriep, UP; Haas, CA; Häussler, U; Wolfart, J | 1 |
| Colbert, CM; Eskin, A; Pita-Almenar, JD; Zou, S | 1 |
| Mazzone, GL; Nistri, A | 1 |
| Borbély, S; Czégé, D; Dobó, E; Mihály, A; Molnár, E; Világi, I | 1 |
| Jiang, L; Kang, D; Kang, J | 1 |
247 other study(ies) available for 2-amino-5-phosphonovalerate and kainic acid
| Article | Year |
|---|---|
Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Iodine Radioisotopes; Kinetics; Male; Neurotoxins; Polyamines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Spermine; Synaptic Membranes; Wasp Venoms | 1991 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
The antinociceptive activity of excitatory amino acids in the rat brainstem: an anatomical and pharmacological analysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Mapping; Brain Stem; Diencephalon; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Medulla Oblongata; Mesencephalon; Microinjections; N-Methylaspartate; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Reticular Formation; Stereotaxic Techniques | 1992 |
The effects of excitatory amino acids on proenkephalin and prodynorphin mRNA levels in the hippocampal dentate gyrus of the rat; an in situ hybridization study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Enkephalins; Functional Laterality; Gene Expression; Hippocampus; Kainic Acid; Kinetics; Male; Microinjections; N-Methylaspartate; Nucleic Acid Hybridization; Protein Precursors; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
mRNA coding for neurotransmitter receptors in a human astrocytoma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Animals; Astrocytoma; Brain Neoplasms; Calcium Channels; Cell Line; Culture Techniques; Female; Glutamates; Humans; Kainic Acid; Kynurenic Acid; Male; Membrane Potentials; Oocytes; Pirenzepine; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus | 1992 |
Kindling-induced long-lasting changes in synaptic transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Bicuculline; Electric Stimulation; Kainic Acid; Kindling, Neurologic; Male; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission | 1992 |
L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Female; Glutamates; Glycine; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Pregnancy; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1992 |
Evidence that non-NMDA receptors are involved in the excitatory pathway from the pedunculopontine region to nigrostriatal dopaminergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; Glutamine; Iontophoresis; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Pons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses | 1992 |
Serotonin1A facilitation of frog motoneuron responses to afferent stimuli and to N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; Animals; Electric Stimulation; Evoked Potentials; Glycine; In Vitro Techniques; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rana pipiens; Serotonin; Spinal Cord; Spinal Nerve Roots; Tetrahydronaphthalenes; Tetrodotoxin; Tropanes | 1992 |
Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding Sites; Binding, Competitive; Estradiol; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Ovariectomy; Progesterone; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Regulation of nerve growth factor and nerve growth factor receptor production by NMDA in C6 glioma cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Blotting, Northern; Bucladesine; Cyclic AMP; Glioma; Kainic Acid; Molecular Sequence Data; N-Methylaspartate; Neoplasm Proteins; Nerve Growth Factors; Quisqualic Acid; Rats; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1992 |
The effect of hypoxia on neurotransmitter phenotype of forebrain cholinergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cell Hypoxia; Cells, Cultured; Choline O-Acetyltransferase; Embryo, Mammalian; Glutamates; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Growth Factors; Neurons; Phenotype; Prosencephalon; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Dual-component miniature excitatory synaptic currents in rat hippocampal CA3 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials, Somatosensory; Hippocampus; Hypertonic Solutions; In Vitro Techniques; Kainic Acid; Kinetics; Membrane Potentials; Microelectrodes; N-Methylaspartate; Neurons; Potassium; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1992 |
Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Epilepsy; Kainic Acid; Male; Neuroglia; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Syndrome | 1992 |
N-acetylaspartylglutamate acts as an agonist upon homomeric NMDA receptor (NMDAR1) expressed in Xenopus oocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cloning, Molecular; Dipeptides; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Oocytes; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Transcription, Genetic; Xenopus laevis | 1992 |
Stimulation of cultured cerebellar granule cells via glutamate receptors induces TRE- and CRE-binding activities mediated by common DNA-binding complexes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Blotting, Northern; Calcium; Cells, Cultured; Cerebellum; Cyclic AMP; DNA-Binding Proteins; Kainic Acid; Magnesium; Mice; Mice, Inbred ICR; Molecular Sequence Data; N-Methylaspartate; Protein Binding; Proto-Oncogene Proteins c-fos; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate | 1992 |
Energy requirements of glutamatergic pathways in rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Energy Metabolism; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kainic Acid; Light; Oxygen Consumption; Quinoxalines; Rabbits; Retina | 1992 |
Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Epilepsy; Glutamine; Kainic Acid; Limbic System; Male; N-Methylaspartate; Neurotransmitter Agents; Pilocarpine; Pons; Rats; Rats, Wistar; Thalamus | 1992 |
Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Glycine; Hypothalamus; Kainic Acid; Magnesium; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Endogenous glutamate stimulates release of alpha-melanocyte-stimulating hormone from the rat hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; alpha-MSH; Animals; Glutamates; Glutamic Acid; Hypothalamus; In Vitro Techniques; Kainic Acid; Male; Neurons; Osmolar Concentration; Pro-Opiomelanocortin; Rats; Rats, Wistar | 1992 |
Effect of magnesium on calcium influx activated by glutamate and its agonists in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Nifedipine; Phencyclidine; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Verapamil | 1992 |
Spontaneous synchronous synaptic calcium transients in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Electrophysiology; Fetus; Fluorescent Dyes; Kainic Acid; Kinetics; Membrane Potentials; Microscopy, Fluorescence; Neurons; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin; Time Factors | 1992 |
Calcitonin gene-related peptide enhances substance P-induced behaviors via metabolic inhibition: in vivo evidence for a new mechanism of neuromodulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Bombesin; Calcitonin Gene-Related Peptide; Catheterization; Dose-Response Relationship, Drug; Drug Synergism; Injections, Spinal; Kainic Acid; Male; Microinjections; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Strychnine; Substance P | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Culture Techniques; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Amygdala; Animals; Bicuculline; Brain Mapping; Carbachol; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Ibotenic Acid; Kainic Acid; Limbic System; Muscimol; Quisqualic Acid; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
Synthesis and biological evaluation of cyclopropyl analogues of 2-amino-5-phosphonopentanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Indicators and Reagents; Kainic Acid; Kinetics; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes; Tritium | 1991 |
GABAA and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kainic Acid; Male; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1991 |
N-methyl-D-aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cells, Cultured; Electrophysiology; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Retinal Ganglion Cells | 1991 |
L-phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes.
Topics: 2-Amino-5-phosphonovalerate; Alzheimer Disease; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glycine; Kainic Acid; N-Methylaspartate; Phosphoserine; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Effects of excitatory amino acids and their antagonists on the light response of luminosity and color-opponent horizontal cells in the turtle (Pseudemys scripta elegans) retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Color Perception; Dizocilpine Maleate; Electrophysiology; Kainic Acid; Light; N-Methylaspartate; Photic Stimulation; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
Regulation of CCK release in cerebral cortex by N-methyl-D-aspartate receptors: sensitivity to APV, MK-801, kynurenate, magnesium and zinc ions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Dizocilpine Maleate; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Potassium; Quisqualic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Sincalide; Zinc | 1991 |
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Diseases; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Rats | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Denervation; Evoked Potentials; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses | 1991 |
Uneven distribution of excitatory amino acid receptors on ventral horn neurones of newborn rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Dendrites; Dose-Response Relationship, Drug; Glutamates; Kainic Acid; Membrane Potentials; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord | 1991 |
Terminal excitability of the corticostriatal pathway. II. Regulation by glutamate receptor stimulation.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cerebral Cortex; Corpus Striatum; Electrophysiology; Glutamates; Kainic Acid; Male; Nerve Endings; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Interactions of glutamate receptor agonists coupled to changes in intracellular Ca2+ in rat cerebellar granule cells in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Fura-2; Glutamates; Kainic Acid; Kinetics; Magnesium; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium; Spectrometry, Fluorescence | 1991 |
Kainate and NMDA toxicity for cultured developing and adult rat spiral ganglion neurons: further evidence for a glutamatergic excitatory neurotransmission at the inner hair cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cochlea; Ganglia; Glutamates; Glutamic Acid; Hair Cells, Auditory, Inner; Immunohistochemistry; In Vitro Techniques; Indicators and Reagents; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Organ of Corti; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Transmission | 1991 |
The contribution of non-NMDA and NMDA receptors to graded bursting activity in the CA1 region of the hippocampus in a chronic model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Chronic Disease; Electric Stimulation; Electrophysiology; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
Receptor sub-types involved in responses of Purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cerebellum; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Excitatory amino acids evoke taurine release from cerebral cortex slices from adult and developing mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotoxins; Potassium; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Secretory Rate; Stimulation, Chemical; Taurine | 1991 |
NMDA and non-NMDA receptors mediate visual responses of neurons in the cat's lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Time Factors; Visual Perception | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Chloride; Cortical Spreading Depression; Electric Stimulation; Evoked Potentials; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Visual Cortex | 1991 |
Voltage-gated and chemically gated ionic channels in the cultured cochlear ganglion neurone of the chick.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium Channels; Cell Membrane Permeability; Chick Embryo; Cochlear Nerve; Ganglia; Glutamates; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Potassium Channels; Sodium Channels | 1990 |
Effects of urethane and ketamine on substance P- and excitatory amino acid-induced behavior in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Injections, Spinal; Isomerism; Kainic Acid; Ketamine; Male; Mice; N-Methylaspartate; Quisqualic Acid; Substance P; Urethane | 1990 |
Glutamate, kainate and quisqualate enhance GABA-dependent chloride uptake in cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Cerebral Cortex; Chloride Channels; Chlorides; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, GABA-A | 1990 |
Glutamate-induced increases in intracellular Ca2+ in cultured frog tectal cells mediated by direct activation of NMDA receptor channels.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Intracellular Membranes; Ion Channels; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Superior Colliculi | 1991 |
Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Nociceptors; Pain; Peptide Fragments; Reaction Time; Substance P; Urethane | 1991 |
Behavioral sensitization to kainic acid and quisqualic acid in mice: comparison to NMDA and substance P responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Capsaicin; Concanavalin A; Drug Tolerance; GABA Antagonists; Glycine; Injections, Spinal; Kainic Acid; Mice; N-Methylaspartate; Quisqualic Acid; Spinal Cord; Substance P | 1991 |
Glutamate-activated channels in adult rat ventral spinal cord cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Membrane; Chick Embryo; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Spinal Cord | 1991 |
Substance P and NMDA receptors mediate a slow nociceptive ventral root potential in neonatal rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Animals, Newborn; Kainic Acid; Membrane Potentials; Nociceptors; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reflex, Monosynaptic; Spinal Nerve Roots; Substance P; Synaptic Transmission | 1991 |
Glutamate receptor agonist-induced inward currents in spinal dorsal horn neurons dissociated from the adult rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Ion Channels; Kainic Acid; N-Methylaspartate; Nerve Fibers; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord | 1991 |
Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Computer Simulation; Ibotenic Acid; Kainic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship | 1990 |
Quinolinate and kainate neurotoxicity in neostriatal cultures is potentiated by co-culturing with neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Kainic Acid; Neurotoxins; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Neurotoxic effects of excitatory amino acids in the mouse spinal cord: quisqualate and kainate but not N-methyl-D-aspartate induce permanent neural damage.
Topics: 2-Amino-5-phosphonovalerate; Aggression; Animals; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methylaspartate; Neurons; Neurotoxins; Pain; Paralysis; Quisqualic Acid; Spinal Cord | 1990 |
Cytotoxic effect of glutamate and its agonists on mouse hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Dipeptides; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Pregnancy; Quinolinic Acid; Quinolinic Acids | 1990 |
Contribution of quisqualate/kainate and NMDA receptors to excitatory synaptic transmission in the rat's visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Electrophysiology; Evoked Potentials; Kainic Acid; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, Neurotransmitter; Visual Cortex | 1990 |
N-methyl-D-aspartate, kainate and quisqualate release endogenous adenosine from rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Animals; Calcium; Cerebral Cortex; Dipeptides; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
Efflux of 45calcium from cultured primary astrocytes: effects of glutamate receptor agonists and antagonists.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Calcium Radioisotopes; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Valine | 1990 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Ion Channels; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Valine | 1986 |
Is substance P a primary afferent neurotransmitter for nociceptive input? IV. 2-Amino-5-phosphonovalerate (APV) and [D-Pro2,D-Trp7,9]-substance P exert different effects on behaviors induced by intrathecal substance P, strychnine and kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P; Valine | 1988 |
Horizontal cells isolated from catfish retina contain two types of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Cations, Divalent; Cell Membrane Permeability; Cells, Cultured; Concanavalin A; Convulsants; Glutamates; Ibotenic Acid; Ictaluridae; Ion Channels; Kainic Acid; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Valine; Zinc | 1989 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Excitatory amino acid receptors in rat locus coeruleus. An extracellular in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Glutamates; In Vitro Techniques; Kainic Acid; Locus Coeruleus; Magnesium; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Valine | 1989 |
Visual responses in adult cat visual cortex depend on N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cats; Electric Conductivity; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Perception | 1989 |
A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Female; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1989 |
Coexistence of NMDA and non-NMDA receptors on turtle horizontal cells revealed using isolated retina preparations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Evoked Potentials, Visual; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles; Valine | 1989 |
Excitatory amino acid receptor-mediated activation of solitarial deglutitive loci.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Deglutition; Dipeptides; Esophagus; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Pharynx; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Different classes of glutamate receptors mediate distinct behaviors in a single brainstem nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Brain Stem; Electric Fish; Electric Organ; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Excitatory amino acids: role in morphine excitation in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; Motor Activity; N-Methylaspartate; Oxadiazoles; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Ketamine acts as a non-competitive N-methyl-D-aspartate antagonist on frog spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Kainic Acid; Ketamine; Magnesium; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana pipiens; Rana temporaria; Spinal Cord; Valine | 1985 |
Evidence for an excitatory amino acid as the transmitter of the auditory nerve in the in vitro mouse cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials; Female; Kainic Acid; Male; Mice; Mice, Inbred C3H; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Neurotransmitter; Valine; Vestibulocochlear Nerve | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
Activity of beta-kainic acid on neocortical neurons in vivo and hippocampal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Hippocampus; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Receptors, Neurotransmitter; Valine | 1986 |
Extracellular studies on the role of N-methyl-D-aspartate receptors in epileptiform activity recorded from the kainic acid-lesioned hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1986 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Phencyclidine selectively inhibits N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Rats; Structure-Activity Relationship; Valine | 1987 |
Excitatory amino acids and intracellular pH in motoneurons of the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Valine | 1986 |
Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anterior Horn Cells; Anura; Aspartic Acid; Drug Interactions; Gyrus Cinguli; Kainic Acid; Ketamine; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Valine | 1987 |
Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apnea; Aspartic Acid; Blood Pressure; Carotid Sinus; Cats; Female; Glutamates; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Oxadiazoles; Phrenic Nerve; Quisqualic Acid; Respiration; Vagotomy; Valine; Vasomotor System | 1987 |
Excitatory amino acid-induced release of 3H-GABA from cultured mouse cerebral cortex interneurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Cerebral Cortex; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Valine | 1987 |
The expression of N-methyl-D-aspartate-receptor-mediated component during epileptiform synaptic activity in hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Epilepsy; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1987 |
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1987 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Actions of excitatory amino acid antagonists on geniculo-cortical transmission in the cat's visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Electric Stimulation; Evoked Potentials, Visual; Geniculate Bodies; Kainic Acid; Optic Chiasm; Photic Stimulation; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex; Visual Pathways | 1988 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
An excitatory amino acid projection from ventromedial hypothalamus to periaqueductal gray in the rat: autoradiographic and electrophysiological evidence.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Autoradiography; Electric Stimulation; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reaction Time; Valine; Ventromedial Hypothalamic Nucleus | 1988 |
Effects of D-(-)-aminophosphonovalerate on behavioral and histological changes induced by systemic kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Hippocampus; Injections, Intraperitoneal; Kainic Acid; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1988 |
Evidence of N-methyl-D-aspartate receptor-mediated modulation of the aortic baroreceptor reflex in the rat nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Kainic Acid; Male; Medulla Oblongata; Oxadiazoles; Pressoreceptors; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
NMDA- and kainate-evoked GABA release from striatal neurones differentiated in primary culture: differential blocking by phencyclidine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Mice; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1988 |
Differential control by N-methyl-D-aspartate and kainate of striatal dopamine release in vivo: a trans-striatal dialysis study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Atropine; Carbachol; Corpus Striatum; Dopamine; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
Amino acids modulate calcium permeability of the plasma membrane of human neuroblastoma cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Calcium; Cell Membrane Permeability; Cysteine; Humans; Kainic Acid; N-Methylaspartate; Neuroblastoma; Neurotransmitter Agents; Tumor Cells, Cultured; Valine | 1988 |
Effects of excitatory amino acids on the oxygen consumption of hippocampal slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Oxadiazoles; Oxygen Consumption; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spider Venoms; Valine | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ganglia, Spinal; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Cerebellum; Electric Stimulation; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neural Inhibition; Oxadiazoles; Quisqualic Acid; Turtles; Valine | 1988 |
Calcium accumulation by glutamate receptor activation is involved in hippocampal cell damage after ischemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Extracellular Space; Hippocampus; Ischemic Attack, Transient; Kainic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Valine | 1988 |
Long-lasting modification of the synaptic properties of rat CA3 hippocampal neurones induced by kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Magnesium; Male; Membrane Potentials; Neurons; Potassium; Rats; Synapses; Tetrodotoxin; Valine | 1988 |
Glutamate-containing dipeptides do not modulate ligand binding at excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Amino Acids; Aminopeptidases; Animals; Binding, Competitive; Dipeptides; Glutamates; Kainic Acid; Leucine; Male; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1986 |
Effects of L-cysteine-sulphinate and L-aspartate, mixed excitatory amino acid agonists, on the membrane potential of cat caudate neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Cysteine; Female; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1987 |
A simple method for quantitative electroencephalographic assessment of drugs with convulsant and anticonvulsant properties.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Diazepam; Electroencephalography; Hippocampus; Injections; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1986 |
Pharmacological antagonists of excitant amino acid action.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aspartic Acid; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Drug; Structure-Activity Relationship | 1981 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
alpha-Amino-omega-phosphono carboxylates block ibotenate but not kainate neurotoxicity in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Diseases; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Neurotoxins; Oxazoles; Pyrrolidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valine | 1982 |
The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Hippocampus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Valine | 1983 |
Blockade of amino acid-induced depolarizations and inhibition of excitatory post-synaptic potentials in rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Rats; Synapses; Valine | 1983 |
A physiologically active kainic acid-preferring receptor in chicken retina.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Chickens; Dipeptides; Kainic Acid; Photoreceptor Cells; Pipecolic Acids; Receptors, Cell Surface; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Valine | 1984 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Seizures | 1982 |
The organotypic tissue culture model of corticostriatal system used for examining amino acid neurotoxicity and its antagonism: studies on kainic acid, quinolinic acid and (-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Animals; Caudate Nucleus; Corpus Striatum; Culture Techniques; Dose-Response Relationship, Drug; Frontal Lobe; Kainic Acid; Microscopy, Electron; Models, Neurological; Nerve Degeneration; Pyridines; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1983 |
Isomers of 2-amino-7-phosphonoheptanoic acid as antagonists of neuronal excitants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats | 1982 |
Simultaneous expression of excitatory postsynaptic potential/spike potentiation and excitatory postsynaptic potential/spike depression in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; Injections, Intraventricular; Kainic Acid; Long-Term Potentiation; Male; Microelectrodes; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Synapses | 1995 |
Pharmacological evidence for involvement of excitatory amino acids in aversive responses induced by intrathecal substance P in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Biphenyl Compounds; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P | 1993 |
Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cell Line; Cycloleucine; Dizocilpine Maleate; Glioma; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Ion Channels; Kainic Acid; Kinetics; Magnesium Chloride; N-Methylaspartate; Neurotoxins; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Signal Transduction; Tumor Cells, Cultured | 1994 |
Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Dendrites; Electric Conductivity; Hippocampus; Kainic Acid; Magnesium; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors; Zinc | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Effects of L-trans-pyrrolidine-2,4-dicarboxylate and L-threo-3-hydroxyaspartate on the binding of [3H]L-aspartate, [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA), [3H]DL-(E)-2-amino-4-propyl-5-phosphono-3-pentenoate (CGP 39653), [3H]6-cya
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Kainic Acid; Neurotransmitter Uptake Inhibitors; Prosencephalon; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 1995 |
Regulation of spontaneous phasic firing of rat supraoptic vasopressin neurones in vivo by glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Kainic Acid; Male; N-Methylaspartate; Oxytocin; Rats; Receptors, Glutamate; Supraoptic Nucleus; Vasopressins | 1995 |
Simultaneous expression of long-term depression of NMDA and long-term potentiation of AMPA receptor-mediated synaptic responses in the CA1 area of the kainic acid-lesioned hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1995 |
N-methyl-D-aspartate induces regular firing patterns in the cat lateral habenula in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Ibotenic Acid; Iontophoresis; Kainic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Stereotaxic Techniques; Thalamus | 1993 |
Norbinaltorphimine protection against N-methyl-D-aspartic acid-induced convulsions and mortality.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Binding, Competitive; Brain; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Naltrexone; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Female; In Vitro Techniques; Ion Channels; Kainic Acid; Oocytes; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Riluzole; RNA, Messenger; Synaptic Transmission; Thiazoles; Xenopus laevis | 1993 |
NMDA receptors mediate neuronal burst firing in rat somatosensory cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1993 |
Kainate toxicity in energy-compromised rat hippocampal slices: differences between oxygen and glucose deprivation.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Electrophysiology; Energy Metabolism; Evoked Potentials; Glucose; Hippocampus; Hypoxia, Brain; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Non-NMDA receptors in the rostral ventrolateral medulla mediate somatosympathetic pressor responses.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Blood Pressure; Electric Stimulation; Female; Histocytochemistry; Ibotenic Acid; Kainic Acid; Medulla Oblongata; Neurons, Afferent; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve; Sympathetic Nervous System; Vagotomy | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
A comparative analysis of the neuroprotective properties of competitive and uncompetitive N-methyl-D-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biomarkers; Cell Death; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Drug Administration Schedule; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections; Injections, Intraperitoneal; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Pipecolic Acids; Piperazines; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blotting, Northern; Calcium; Cells, Cultured; Electrophysiology; Gene Expression Regulation; Genes, fos; Genes, jun; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Hippocampus; Immunohistochemistry; Kainic Acid; Kynurenic Acid; Neurons; Nifedipine; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1995 |
Modulation of D-[2,3 3H]aspartate release from rat forebrain slices by non-NMDA receptor agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Kynurenic Acid; Male; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Tritium | 1995 |
Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Glycine; Hippocampus; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1994 |
Bilateral intranigral NMDA blockade increases status duration and neuronal injury from systemic kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Carbon Dioxide; Diazepam; Drug Synergism; Electroencephalography; Functional Laterality; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Injections, Intravenous; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neurons; Oxygen; Partial Pressure; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors | 1994 |
Deep prepiriform cortex modulates kainate-induced hippocampal injury.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Electroencephalography; Excitatory Amino Acids; GABA Antagonists; Hippocampus; Kainic Acid; Male; Neural Pathways; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Seizures; Synaptic Transmission | 1994 |
Decreased excitotoxic sensitivity in the olfactory cortex of adult rats after neonatal NMDA blockade.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Animals, Newborn; Enzyme Induction; Hippocampus; Kainic Acid; Nerve Degeneration; Olfactory Bulb; Ornithine Decarboxylase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1994 |
Stress-induced dopamine release in the neostriatum: evaluation of the role of action potentials in nigrostriatal dopamine neurons or local initiation by endogenous excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corpus Striatum; Dopamine; Electroshock; Homovanillic Acid; Kainic Acid; Male; N-Methylaspartate; Neostriatum; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Stress, Psychological; Substantia Nigra; Tetrodotoxin | 1993 |
N-methyl-D-aspartate receptors contribute to guanidinosuccinate-induced convulsions in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Drug Interactions; Female; Glutamates; Glutamic Acid; Guanidines; Kainic Acid; Ketamine; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate; Seizures; Succinates | 1993 |
Excitatory amino acid-induced phosphoinositide hydrolysis in Müller glia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Chickens; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Retina; Tritium | 1993 |
Serotonin differentially modulates responses mediated by specific excitatory amino acid receptors in the rat locus coeruleus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Electrophysiology; Iontophoresis; Kainic Acid; Locus Coeruleus; Male; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Serotonin | 1993 |
Neonatal irradiation prevents the formation of hippocampal mossy fibers and the epileptic action of kainate on rat CA3 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Electric Stimulation; Electrophysiology; Epilepsy; Gamma Rays; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; Nerve Fibers; Neurons, Afferent; Potassium; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar | 1994 |
Formation and electrophysiological actions of the arachidonic acid metabolites, hepoxilins, at nanomolar concentrations in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8,11,14-Eicosatrienoic Acid; Animals; Electrophysiology; Gas Chromatography-Mass Spectrometry; Hippocampus; Kainic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-B | 1994 |
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium | 1994 |
Fos protein induction, neuropathology, and pharmacological protection after excitotoxic brain insult.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Injections; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Time Factors | 1994 |
The anterior pituitary gland as a possible site of action of kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Follicle Stimulating Hormone; Kainic Acid; Luteinizing Hormone; Male; Morphine; Pituitary Gland, Anterior; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Kainic Acid | 1994 |
Injections of excitatory amino acid antagonists into the median raphe nucleus produce hippocampal theta rhythm in the urethane-anesthetized rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Anesthesia; Animals; Anticonvulsants; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Injections; Kainic Acid; Male; Quisqualic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Theta Rhythm; Urethane | 1994 |
The effects of intrathecal administration of excitatory amino acid agonists and antagonists on the initiation of locomotion in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Decerebrate State; Electromyography; Glutamates; Glutamic Acid; Hindlimb; Injections, Spinal; Kainic Acid; Laminectomy; Locomotion; Motor Activity; Muscles; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Spinal Cord; Time Factors | 1993 |
Monosynaptic GABA-mediated inhibitory postsynaptic potentials in CA1 pyramidal cells of hyperexcitable hippocampal slices from kainic acid-treated rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1993 |
Optical imaging of parallel fiber activation in the rat cerebellar cortex: spatial effects of excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebellar Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Involvement of excitatory amino acids in the activity of swallowing-related neurons of the ventro-lateral medulla.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Dipeptides; Electric Stimulation; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
Effect of excitatory amino acid on the hypothalamo-pituitary-adrenal axis in the rat during the stress-hyporesponsive period.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; Amino Acids; Animals; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Pituitary-Adrenal System; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Stress, Physiological | 1993 |
Glutamate effects on calcium homeostasis in cerebellar granule cells in primary cultures grown under depolarizing and nondepolarizing conditions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Cytosol; Glutamates; Glutamic Acid; Homeostasis; Kainic Acid; Ketamine; Mice; Nerve Tissue Proteins; Neuromuscular Depolarizing Agents; Potassium; Quisqualic Acid | 1993 |
In vivo regulation of extracellular dopamine in the neostriatum: influence of impulse activity and local excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Corpus Striatum; Dialysis; Dopamine; Exocytosis; Extracellular Space; Kainic Acid; Kynurenic Acid; Microchemistry; Models, Neurological; N-Methylaspartate; Nerve Endings; Neurotoxins; Prosencephalon; Quinoxalines; Rats; Substantia Nigra; Tetrodotoxin | 1993 |
Effects of serotonin on fictive locomotion coordinated by a neural network deprived of NMDA receptor-mediated cellular properties.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Kainic Acid; Lampreys; Locomotion; Nerve Net; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Serotonin; Spinal Cord; Swimming | 1993 |
Heterogeneity of synaptic glutamate receptors on CA3 stratum radiatum interneurones of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Hippocampus; Interneurons; Kainic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Tetrodotoxin | 1993 |
MK-801 and phencyclidine act at phencyclidine sites that are not linked to N-methyl-D-aspartate activity to inhibit behavioral sensitization to kainate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; N-Methylaspartate; Nociceptors; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Receptors, sigma; Spinal Cord | 1993 |
Electrophysiological characterization of excitatory amino acid responses in rat lateral parabrachial neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Evoked Potentials; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Male; N-Methylaspartate; Neurons; Pons; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Serine; Time Factors | 1993 |
Kainate elicits elevated nuclear calcium signals in retinal neurons via calcium-induced calcium release.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Caffeine; Calcium; Cells, Cultured; Kainic Acid; Microscopy, Fluorescence; Quinoxalines; Rats; Rats, Wistar; Retinal Ganglion Cells; Signal Transduction; Sodium | 1993 |
Contribution of spinal N-methyl-D-aspartic acid receptors to control of sympathetic outflow by the paraventricular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Electric Stimulation; Heart Rate; Injections, Spinal; Kainic Acid; Kidney; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Renal Circulation; Spinal Cord; Sympathetic Nervous System | 1993 |
Septal and hippocampal glutamate receptors modulate the output of acetylcholine in hippocampus: a microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Septal Nuclei | 1996 |
Glutamate receptor ion channel properties predict vulnerability to cytotoxicity in a transfected nonneuronal cell line.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Benzothiadiazines; Cell Line; Cell Survival; Concanavalin A; Dizocilpine Maleate; DNA Primers; Evoked Potentials; Glutamic Acid; Humans; Ion Channels; Kainic Acid; Kidney; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Transfection | 1996 |
Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Weight; Circadian Rhythm; Eating; Excitatory Amino Acid Antagonists; Food Deprivation; Glutamic Acid; Hypothalamic Area, Lateral; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1996 |
Distribution of neurones expressing inwardly rectifying and Ca(2+)-permeable AMPA receptors in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Synaptic Transmission | 1996 |
Effects of excitatory amino acids on the hypothalamic-pituitary-adrenal axis of the neonatal rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenocorticotropic Hormone; Age Factors; Animals; Animals, Newborn; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hypothalamo-Hypophyseal System; Kainic Acid; Male; N-Methylaspartate; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Stress, Physiological; Time Factors | 1996 |
Glutamate receptors and calcium entry mechanisms for domoic acid in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Excitatory Amino Acid Antagonists; Kainic Acid; Neurotoxins; Nimodipine; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate | 1996 |
Electrophysiological characterization of non-NMDA glutamate receptors on cultured intermediate lobe cells of the rat pituitary.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Pituitary Gland; Quisqualic Acid; Rats; Receptors, Glutamate | 1996 |
Regulation of dopamine uptake in rat striatal tissue by NMDA receptors as measured using rotating disk electrode voltammetry.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dopamine; Dopamine Antagonists; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Kinetics; Male; N-Methylaspartate; Neostriatum; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 1996 |
The role of excitatory neurotransmitters in seizure-induced neuronal injury in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Cerebral Cortex; Diazepam; Electroencephalography; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Male; Microdialysis; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Status Epilepticus | 1996 |
Comparison of effects induced by toxic applications of kainate and glutamate by glucose deprivation on area CA1 of rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glucose; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Osmolar Concentration; Potassium; Rats; Rats, Wistar | 1996 |
NMDA and non-NMDA receptors mediate taste afferent inputs to cortical taste neurons in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Kainic Acid; N-Methylaspartate; Neurons; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Taste | 1995 |
Brainstem-mediated locomotion and myoclonic jerks. II Pharmacological effects.
Topics: 2-Amino-5-phosphonovalerate; Animals; Basal Ganglia; Brain Stem; Cats; Corticotropin-Releasing Hormone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Locomotion; Male; Microinjections; Myoclonus; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate | 1997 |
Effect of glutamate receptor phosphorylation by endogenous protein kinases on electrical activity of isolated postsynaptic densities of rat cortex and hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Cerebral Cortex; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Kainic Acid; Long-Term Potentiation; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Protein Kinases; Quisqualic Acid; Rats; Receptors, Glutamate; Synapses | 1997 |
Non-NMDA but not NMDA blockade at deep prepiriform cortex protects against hippocampal cell death in status epilepticus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Cell Death; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Neuroprotective Agents; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reproducibility of Results; Status Epilepticus | 1997 |
Spontaneous bursting activity of dopaminergic neurons in midbrain slices from immature rats: role of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Dopamine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Mesencephalon; N-Methylaspartate; Neurons; Periodicity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Regulation of cerebral microvessels by glutamatergic mechanisms.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microcirculation; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses; Vasoconstriction; Vasodilation | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
EMD 95885, a new eliprodil analogue with higher affinity for the N-methyl-D-aspartate (NMDA) receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
NMDA-mediated facilitation in the echo-delay tuned areas of the auditory cortex of the mustached bat.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Animals; Auditory Cortex; Chiroptera; Echolocation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate | 1997 |
Kainate receptors presynaptically downregulate GABAergic inhibition in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Cells, Cultured; Electric Stimulation; Electroencephalography; Embryo, Mammalian; Epilepsy; Evoked Potentials; Female; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Synaptic Transmission; Tetrodotoxin | 1997 |
Inwardly rectifying and Ca2+-permeable AMPA-type glutamate receptor channels in rat neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Calcium; Calcium Channels; Electric Conductivity; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Membrane Potentials; Nerve Fibers; Neurons; Occipital Lobe; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, GABA-A; Spermine; Synapses | 1997 |
A fast synaptic potential mediated by NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Goldfish; Kainic Acid; Ketamine; Microelectrodes; Neurons; Piperazines; Pons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists; Synapses; Synaptic Transmission | 1997 |
Physiological unmasking of new glutamatergic pathways in the dentate gyrus of hippocampal slices from kainate-induced epileptic rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Dentate Gyrus; Electric Stimulation; Electrophysiology; Epilepsy; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Humans; In Vitro Techniques; Kainic Acid; Male; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Values | 1998 |
Chlormethiazole anticonvulsive efficacy diminished by N-methyl-D-aspartate but not kainate in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Chlormethiazole; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
Characterization of the N-methyl-D-aspartate (NMDA) receptor in the embryonic chick brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Blotting, Western; Brain; Brain Chemistry; Calcium; Cell Count; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Immunohistochemistry; Kainic Acid; Neurons; Receptors, N-Methyl-D-Aspartate; Telencephalon | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
Evidence that excitatory amino acid receptors within the temporomandibular joint region are involved in the reflex activation of the jaw muscles.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Brain Stem; Dose-Response Relationship, Drug; Electromyography; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Jaw; Kainic Acid; Lidocaine; Male; Masseter Muscle; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Trigeminal Nerve | 1998 |
Mossy fibre innervation is not required for the development of kainic acid toxicity in organotypic hippocampal slice cultures.
Topics: Animals; Cell Death; Cell Survival; Hippocampus; In Vitro Techniques; Kainic Acid; Microelectrodes; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Pathways; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Time Factors; Valine | 1998 |
Efferent pathways involved in the running activity originate in the ventromedial hypothalamus of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gait; Kainic Acid; Male; Neurons, Efferent; Neurotransmitter Agents; Pons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Running; Thalamic Nuclei; Ventromedial Hypothalamic Nucleus | 1998 |
Regulation of vasopressin release by ionotropic glutamate receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Hypothalamo-Hypophyseal System; Kainic Acid; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 1998 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Cardiovascular responses to microinjections of excitatory amino acids into the area postrema of the rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Cerebral Ventricles; Cycloleucine; Decerebrate State; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Tachycardia; Urethane | 1999 |
Properties of NMDA receptors in rat spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Magnesium; Male; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Some interactions of L-DOPA and its related compounds with glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Kainic Acid; Levodopa; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Xenopus laevis | 1999 |
A 'long-term-potentiation-like' facilitation of hippocampal synaptic transmission induced by the nootropic nefiracetam.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Bungarotoxins; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Indoles; Isoquinolines; Kainic Acid; Long-Term Potentiation; Maleimides; Mecamylamine; N-Methylaspartate; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidinones; Rats; Receptors, Nicotinic; Sulfonamides; Synaptic Transmission | 1999 |
Role of glutamate receptor subtypes in the lamprey respiratory network.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kynurenic Acid; Lampreys; Neurons; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Respiration | 1999 |
Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Growth Factors; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; Retina | 1999 |
Reduced Mg2+ blockade of synaptically activated N-methyl-D-aspartate receptor-channels in CA1 pyramidal neurons in kainic acid-lesioned rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Kainic Acid; Lidocaine; Magnesium; Male; Models, Neurological; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reference Values; Synaptic Transmission | 1999 |
Involvement of NMDA and non-NMDA receptors in transmission of spinal visceral nociception in cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Excitatory Amino Acid Agonists; Female; Kainic Acid; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Splanchnic Nerves; Viscera | 1999 |
Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channel Blockers; Cycloleucine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Lumbosacral Region; Motor Neurons; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spider Venoms; Spinal Cord | 2000 |
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 2000 |
Participation of NMDA and kainate receptors of paraventricular nucleus in cardiovascular responses to glutamate receptor agonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Kainic Acid; Male; Microinjections; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
Long-lasting depolarizations in mitral cells of the rat olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
Administration of either non-NMDA receptor agonists or NMDA receptor antagonists into the substantia nigra or the globus pallidus reduces the psychostimulant effect of high helium pressure on locomotor activity in rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atmospheric Pressure; Excitatory Amino Acid Agonists; Globus Pallidus; Helium; Injections; Kainic Acid; Male; Motor Activity; Myoclonus; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1999 |
Modulation of GABAergic signaling among interneurons by metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neural Inhibition; Propionates; Quinoxalines; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission | 2000 |
Kainic acid-induced neurotrophic activities in developing cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antibodies; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GTP-Binding Proteins; Kainic Acid; Nerve Growth Factor; Neurons; Neuroprotective Agents; Phosphatidylinositols; Phosphorylation; Pregnancy; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, trkA; Receptors, AMPA; Receptors, Kainic Acid; Signal Transduction; Type C Phospholipases | 2000 |
Glutamate receptor activation in the kindled dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dentate Gyrus; Entorhinal Cortex; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; Kainic Acid; Kindling, Neurologic; Neural Pathways; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
Ontogeny of ionotropic glutamate receptor expression in human fetal brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Brain Chemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Gene Expression Regulation, Developmental; Humans; Indoles; Kainic Acid; Piperidines; Radioligand Assay; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tritium | 2001 |
Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Aminobutyrates; Animals; Bicuculline; Drug Design; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Substantia Nigra; Xanthenes | 2001 |
A kainate receptor increases the efficacy of GABAergic synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Benzodiazepines; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neurons; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Staurosporine; Synapses; Tetradecanoylphorbol Acetate; Tetrodotoxin | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration.
Topics: 2-Amino-5-phosphonovalerate; Animals; C-Reactive Protein; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Genetic Predisposition to Disease; Immunohistochemistry; Kainic Acid; Limbic System; Male; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Neuroprotective Agents; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serum Amyloid P-Component | 2001 |
Delayed postnatal development of NMDA receptor function in medium-sized neurons of the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Central Nervous System Stimulants; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Kinetics; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, Kainic Acid; Synapses; Synaptic Transmission; Temperature; Thalamus | 2001 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Receptor-activated calcium signals in tangentially migrating cortical cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Calcium; Calcium Signaling; Cell Movement; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA-A Receptor Agonists; Kainic Acid; Male; Muscimol; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Tetrodotoxin | 2002 |
A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Arthropod Venoms; Calcium; Calcium Channel Blockers; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; In Vitro Techniques; Isoquinolines; Kainic Acid; Long-Term Potentiation; Magnesium; Membrane Potentials; Mossy Fibers, Hippocampal; Nifedipine; Patch-Clamp Techniques; Rats; Receptors, Kainic Acid; Ryanodine; Synaptic Transmission; Thapsigargin | 2003 |
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium | 2004 |
Characterisation of the effects of ATPA, a GLU(K5) kainate receptor agonist, on GABAergic synaptic transmission in the CA1 region of rat hippocampal slices.
Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Membrane Potentials; Neural Inhibition; Propionates; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission; Valine | 2004 |
Differential effects of NMDA and AMPA/kainate receptor antagonists on superoxide production and MnSOD activity in rat brain following intrahippocampal injection.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Kainic Acid; Male; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Time Factors | 2004 |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; N-Methylaspartate; Pyrazoles; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thermodynamics; Tritium | 2004 |
Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons.
Topics: Analysis of Variance; Animals; Bicuculline; Blotting, Western; Cyclic Nucleotide-Gated Cation Channels; Dendrites; Electroencephalography; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Immunohistochemistry; In Vitro Techniques; Ion Channels; Kainic Acid; Male; Membrane Potentials; Muscle Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Seizures; Valine | 2004 |
Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Dicarboxylic; Animals; Benzodiazepines; Cyclopropanes; Excitatory Postsynaptic Potentials; Gene Deletion; GluK2 Kainate Receptor; Glycine; Isoquinolines; Isoxazoles; Kainic Acid; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Patch-Clamp Techniques; Potassium; Propionates; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission | 2004 |
GABAB receptors in the medial septum/diagonal band slice from 16-25 day rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-A; Septum Pellucidum; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2005 |
Cortical glutamatergic markers in schizophrenia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; In Situ Hybridization; Kainic Acid; Male; Middle Aged; Postmortem Changes; Radioligand Assay; Receptors, Glutamate; Schizophrenia; Tritium | 2005 |
Presynaptic modulation of synaptic transmission by pregnenolone sulfate as studied by optical recordings.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Analysis of Variance; Animals; Benzylidene Compounds; Bicuculline; Bungarotoxins; Calcium; Calcium Channel Blockers; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ethylenediamines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Haloperidol; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Pregnenolone; Presynaptic Terminals; Pyridines; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin; Time Factors | 2005 |
Electrophysiological properties of human hypothalamic hamartomas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Bicuculline; Cadmium Chloride; Child; Child, Preschool; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Glutamic Acid; Hamartoma; Humans; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Infant; Isoenzymes; Kainic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periodicity; Phosphopyruvate Hydratase; Potassium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Valine | 2005 |
Tunicamycin decreases the probability of single-channel openings for N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Probability; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tunicamycin | 2006 |
Differential effect of glutamate transporter inhibition on EPSCs in the morphine naïve and morphine tolerant neonatal spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Analysis of Variance; Animals; Aspartic Acid; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Morphine; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
D-Serine inhibits AMPA receptor-mediated current in rat hippocampal neurons.
Topics: Action Potentials; Amino Acids; Aminobutyrates; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Molecular Structure; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Valine | 2007 |
Mechanisms of seizure-induced 'transcriptional channelopathy' of hyperpolarization-activated cyclic nucleotide gated (HCN) channels.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Calcium; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Situ Nick-End Labeling; In Vitro Techniques; Ion Channels; Kainic Acid; Potassium Channels; Rats; Rats, Sprague-Dawley; Seizures | 2008 |
Decreased glutamate transport enhances excitability in a rat model of cortical dysplasia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Malformations of Cortical Development; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2008 |
Neuroprotection of locomotor networks after experimental injury to the neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cell Survival; Disease Models, Animal; Drug Therapy, Combination; Efferent Pathways; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Locomotion; Motor Neurons; Nerve Fibers, Myelinated; Neurons; Neuroprotective Agents; Posterior Horn Cells; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors | 2010 |
Involvement of the thalamic parafascicular nucleus in mesial temporal lobe epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biophysical Phenomena; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Functional Laterality; GABA-A Receptor Agonists; Hippocampus; Intralaminar Thalamic Nuclei; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Muscimol; N-Methylaspartate; Neurons; Statistics, Nonparametric; Time Factors; Wakefulness | 2010 |
Septotemporal position in the hippocampal formation determines epileptic and neurogenic activity in temporal lobe epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Convulsants; Disease Models, Animal; Doublecortin Domain Proteins; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; Hippocampus; Kainic Acid; Luminescent Proteins; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Patch-Clamp Techniques; Picrotoxin | 2012 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
S100β as an early biomarker of excitotoxic damage in spinal cord organotypic cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Biomarkers; Blotting, Western; Cell Count; Colchicine; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Organ Culture Techniques; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; Spinal Cord | 2014 |
Repeated application of 4-aminopyridine provoke an increase in entorhinal cortex excitability and rearrange AMPA and kainate receptors.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzodiazepines; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Seizures | 2015 |
Potentiation of tonic GABAergic inhibition by activation of postsynaptic kainate receptors.
Topics: Action Potentials; Animals; Animals, Newborn; Benzodiazepines; Biophysics; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; Hippocampus; Humans; In Vitro Techniques; Kainic Acid; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2015 |