2-amino-5-phosphonovalerate has been researched along with glycine in 262 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (5.73) | 18.7374 |
| 1990's | 133 (50.76) | 18.2507 |
| 2000's | 87 (33.21) | 29.6817 |
| 2010's | 27 (10.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anis, NA; Bukownik, R; Eldefrawi, AT; Eldefrawi, ME; Goodnow, RA; Nakanishi, K; Usherwood, PN | 1 |
| Helm, SW; Henzi, V; MacDermott, AB; Reichling, DB | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Lipton, SA; Zhang, D | 1 |
| Beyer, C; Caba, M; Komisaruk, BR; Lòpez-Colomè, AM | 1 |
| Peeters, BW; Vanderheyden, PM | 1 |
| Besser, GM; Costa, A; Forsling, ML; Grossman, A; Hucks, D; Yasin, SA | 1 |
| Aceves, J; Góngora-Alfaro, JL; Hernández, S; Martínez-Fong, D; Rosales, MG | 1 |
| Hayashi, M; Hirose, E; Ito, I; Kohda, A; Mitsunaga, S; Sugiyama, H; Tanabe, S | 1 |
| Inokuchi, H; Nishi, S; Polosa, C; Trzebski, A; Yoshimura, M | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Klunk, WE; McClure, RJ; Pettegrew, JW | 1 |
| Chabert, R; Eybalin, M; Ladrech, S; Puel, JL; Pujol, R | 1 |
| Beilin, B; Cohn, S; Ginzburg, R; Seltzer, Z | 1 |
| Higashi, H; Inokuchi, H; Nishi, S; Nose, I | 1 |
| Canton, H; Colpaert, F; Lehmann, J | 1 |
| Bekkers, JM; Stevens, CF | 1 |
| Benveniste, M; Mayer, ML | 2 |
| Morita, Y; Nishimura, S; Sorimachi, M | 1 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Frusciante, MJ; Javitt, DC; Nussenzveig, IZ; Sircar, R; Wong, ML; Zukin, SR | 1 |
| Jaarsma, D; Korf, J; Sebens, JB | 1 |
| Fink, K; Göthert, M | 1 |
| Gündel, J; Matthies, H; Steinhäuser, C | 1 |
| Khodorov, B; Sokolova, S; Uteshev, V; Zilberter, Y | 1 |
| Larson, AA; Sun, XF | 1 |
| Linn, DM; Massey, SC | 1 |
| Insel, TR; Skolnick, P; Trullas, R; Winslow, JT | 1 |
| Weiss, S | 1 |
| Grudt, TJ; Jahr, CE | 1 |
| Benveniste, M; Mayer, ML; Mienville, JM; Sernagor, E | 1 |
| Okamoto, K; Sakai, Y; Sekiguchi, M | 1 |
| Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA | 1 |
| Ashbeck, GA; Tauck, DL | 1 |
| Dingledine, R; McNamara, D | 1 |
| Abe, K; Saito, H; Watanabe, Y; Xie, FJ | 1 |
| Cordi, AA; Monahan, JB; Reisse, J | 1 |
| Nag, S; Riopelle, RJ | 1 |
| Dow, KE; Riopelle, RJ | 1 |
| Gonzales, RA; Woodward, JJ | 1 |
| Biesterfeldt, JP; Compton, RP; Cordi, AA; Hood, WF; Lanthorn, TH; Monahan, JB; Vazquez, MI; Wood, PL | 1 |
| Finkbeiner, S; Stevens, CF | 1 |
| Javitt, DC; Zukin, SR | 1 |
| Dudek, S; Joly, M; Lynch, G; Muller, D; Schottler, F; Thibault, O | 1 |
| Alesiani, M; Cherici, G; Galli, A; Mori, F; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Dun, NJ; Minota, S; Miyazaki, T; Read, HL; Wang, MY | 1 |
| Aizenman, E; Rosenberg, PA | 1 |
| Gallagher, JP; Hasuo, H | 1 |
| Evans, RH; Krijzer, F; Long, SK | 1 |
| Kloog, Y; Nadler, V; Sokolovsky, M | 1 |
| Krishtal, OA; Vrublevsky, SV | 1 |
| Fletcher, EJ; Lodge, D | 1 |
| Mayer, ML; Vyklický, L; Westbrook, GL | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Lovinger, DM; Weight, FF | 1 |
| Ikeda, H; Sheardown, MJ | 1 |
| Coco, S; Fumagalli, G; Matteoli, M; Verderio, C | 1 |
| Brotchie, JM; Carroll, CB; Holloway, V; Mitchell, IJ | 1 |
| Hardy, M; Lee, VM; Pleasure, D; Pleasure, SJ; Reddy, UR; Shi, QY; Tang, CM; Younkin, DP | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Banks, MD; Fowler, CJ; Sandberg, MP | 1 |
| Bordi, F; Ugolini, A | 1 |
| Bigge, CF; Borosky, SA; Li, JH; Ortwine, DF; Vartanian, MG; Williamson, RM | 1 |
| Opitz, T; Pidoplichko, VI; Reymann, KG; Shinozaki, H; Wilsch, VW | 1 |
| Bashir, ZI; Collingridge, GL | 1 |
| Casabona, G; Reymann, KG; Riedel, G | 1 |
| Flores, A; Soto, E; Vega, R | 1 |
| Aronstam, RS; Dennison, RL; Martin, DC | 1 |
| Jahr, CE; Shepherd, D; Tong, G | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M | 1 |
| Chetkovich, DM; Sweatt, JD | 1 |
| Coderre, TJ | 1 |
| Reynolds, IJ | 1 |
| Layer, RT; Nowak, G; Paul, IA; Skolnick, P | 1 |
| Gerbling, KP; Harde, C; Laber, B; Neff, KH; Nordhoff, E; Pohlenz, HD | 1 |
| Eróstegui, C; Flores, A; Soto, E; Vega, R | 1 |
| Oblin, A; Schoemaker, H | 1 |
| Challis, RA; Gray, DW; Mistry, R; Nahorski, SR | 1 |
| Biggio, G; Foddi, MC; Ghiani, CA; Motzo, C; Serra, M | 1 |
| Han, D; Ogita, K; Yoneda, Y | 1 |
| Carpenter, DO; Hori, N | 1 |
| Kamiya, H; Sawada, S; Yamamoto, C | 1 |
| Boje, KM; Skolnick, P; Wong, G | 1 |
| Komuro, H; Rakic, P | 1 |
| Lux, HD; Parsons, CG; Zong, X | 1 |
| Layer, RT; Nowak, G; Paul, IA; Skolnick, P; Trullas, R | 1 |
| Abe, K; Saito, H | 1 |
| Giberti, A; Mugnaini, M; Ratti, E; van Amsterdam, FT | 1 |
| Orrego, F; Riquelme, G; Villanueva, S; Wyneken, U | 2 |
| Golding, NL; Oertel, D | 1 |
| Atack, JR; Barton, C; Cockett, W; Cook, SM; Gilbert, E; Grimwood, S; Hutson, PH; Le Bourdellès, B; McKernan, RM; Myers, J; Ragan, CI; Whiting, PJ; Wingrove, PB | 1 |
| Kobayashi, K; Manabe, T; Takahashi, T | 1 |
| Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
| Faber, DS; Korn, H; Titmus, MJ | 1 |
| Gribkoff, VK; Molinoff, PB; Zhong, J | 1 |
| Faber, DS; Lewis, CA | 1 |
| Aistrup, GL; Babcock, KK; Kumar, KN; Michaelis, EK; Schowen, RL; Szentirmay, M | 1 |
| Liu, YB; Pasternak, JF; Trommer, BL | 1 |
| Burke, JP; Hablitz, JJ | 1 |
| DiMicco, J; Monroe, AJ | 1 |
| Bum, EN; Herrling, PL; Meier, CL; Urwyler, S; Wang, Y | 1 |
| Attwell, D; Sarantis, M; Takahashi, M | 1 |
| Glitsch, M; Llano, I; Marty, A | 1 |
| Anwyl, R; Breakwell, NA; Huang, L; Rowan, MJ | 1 |
| Betz, H; Hirai, H; Kuhse, J; Laube, B; Sturgess, M | 1 |
| Arnelle, DR; Choi, YB; D'Emilia, DM; Kim, WK; Kumar, S; Lipton, SA; Rayudu, PV; Stamler, JS | 1 |
| McCarthy, KD; Shao, Y | 1 |
| Barth, A; Malouf, AT; Newell, DW; Ricciardi, TN | 1 |
| Leslie, SW; Randall, PK; Robichon, R | 1 |
| O'Connor, JJ; O'Leary, DM | 1 |
| Billard, JM; Dutar, P; Jouvenceau, A | 1 |
| Kiehn, O; Kjaerulff, O | 1 |
| Chub, N; O'Donovan, MJ | 1 |
| Camarasa, J; Camins, A; Escubedo, E; Gabriel, C; Pallàs, M; Sureda, FX | 1 |
| Chai, CY; Kuo, JS; Wang, Y; Wu, WC | 1 |
| Compagnone, NA; Mellon, SH | 1 |
| Legutko, B; Nowak, G; Popik, P; Skolnick, P | 1 |
| Currás, MC; Meeker, RB; Rack, PG | 1 |
| Isaacson, JS; Strowbridge, BW | 1 |
| Bruno, V; Fiore, L; Nicoletti, F; Wroblewska, B; Wroblewski, JT | 1 |
| Golshani, P; Jones, EG; Warren, RA | 1 |
| Braunewell, KH; Manahan-Vaughan, D; Reymann, KG | 1 |
| Boje, KM; Lakhman, SS | 1 |
| Khodorov, BI; Koshelev, SG; Sobolevsky, AI | 1 |
| Bongianni, F; Dubuc, R; Grillner, S; Ohta, Y; Vinay, L | 1 |
| Carlen, PL; Perez Velazquez, JL; Skinner, FK; Tian, GF; Wu, CP; Zhang, L; Zhang, Y | 1 |
| DeLorenzo, RJ; Pal, S; Sombati, S | 1 |
| Manahan-Vaughan, D; Nakic, M; Reymann, KG; Schachner, M | 1 |
| Hyson, RL | 1 |
| Bergeron, R; Coyle, JT; Greene, RW; Meyer, TM | 1 |
| Huang, W; Simpson, RK | 1 |
| Allgaier, C; Feuerstein, TJ; Illes, P; Müller, D; Scheibler, P | 1 |
| Haas, HL; Yanovsky, Y | 1 |
| Masgrau, R; Picatoste, F; Sarri, E; Servitja, JM | 1 |
| Abdrachmanova, G; Palecek, JI; Vlachová, V; Vyklick, L | 1 |
| Hinoi, E; Ogita, K; St'astny, F; Yoneda, Y | 1 |
| Bear, MF; Huganir, RL; Philpot, BD; Quinlan, EM | 1 |
| Bongianni, F; Deliagina, TG; Grillner, S | 1 |
| Bashir, ZI; Brown, MW; Tillett, CW; Ziakopoulos, Z | 1 |
| Chéry, N; de Koninck, Y | 1 |
| Araque, A; Haydon, PG; Sanzgiri, RP | 1 |
| Bernardi, G; Guatteo, E; Knöpfel, T; Mercuri, NB | 1 |
| Standley, CA | 1 |
| Kinnamon, SC; Lin, W | 1 |
| Ezure, K; Miyazaki, M; Tanaka, I | 1 |
| Miller, ED; Myhr, KL; Wong, RO; Wong, WT | 1 |
| Danysz, W; Karcz-Kubicha, M; Wedzony, K; Zajaczkowski, W | 1 |
| Ataka, T; Baba, H; Kohno, T; Kumamoto, E; Okamoto, M; Shimoji, K; Yoshimura, M | 1 |
| Kato, K; Li, ST; Mikoshiba, K | 1 |
| Keele, NB; Neugebauer, V; Shinnick-Gallagher, P; Zinebi, F | 1 |
| Hamba, M; Onodera, K; Takahashi, T | 1 |
| Dong, XP; Wang, DS; Xu, TL | 1 |
| Clarke, G; Collingridge, GL; Fitzjohn, SM; Tolchard, S | 1 |
| Blatow, M; Giuffrida, R; Monyer, H; van Hooft, JA | 1 |
| Ross, ST; Soltesz, I | 1 |
| Bunney, BS; Shi, WX; Zhang, XX | 1 |
| Hirai, H; Launey, T | 1 |
| Alojado, ME; Anchisi, D; Knöpfel, T; Strata, P; Tempia, F | 1 |
| Nishiyama, T | 1 |
| Changeux, JP; Klink, R; Korn, H; Léna, C; Tsuneki, H | 1 |
| Ben-Ari, Y; Dzhala, VI; Luhmann, HJ | 1 |
| Queen, AL; Vezina, P | 1 |
| Ardenghi, PG; Barros, DM; Izquierdo, I; Izquierdo, LA; Medina, JH; Mello e Souza, T; Pereira, P | 1 |
| Chu, Z; Hablitz, JJ | 1 |
| Assmann, S; Foley, EC; Kinney, HC; Panigrahy, A; Rosenberg, PA | 1 |
| Augustine, GJ; Finch, EA; Hashimoto, K; Hayasaka, S; Inouye, M; Kano, M; Khiroug, L; Miyata, M; Oda, SI; Takagishi, Y | 1 |
| Yang, SN | 1 |
| Blanc, G; Darracq, L; Drouin, C; Glowinski, J; Tassin, JP | 1 |
| Ankri, N; Faber, DS; Hatta, K; Korn, H | 1 |
| Aihara, H; Kondoh, T; Nishizaki, T; Tamaki, N | 1 |
| Bhave, G; Carlton, SM; Gereau , RW; Karim, F | 1 |
| Bowery, NG; Bunnemann, B; Corsi, M; Meoni, P; Mugnaini, M | 1 |
| Arora, M; Attwell, D; Boyde, A; Gray, C; Jones, S; Marie, H; Tanaka, K | 1 |
| Bradley, SR; Conn, PJ; Marino, MJ; Wittmann, M | 1 |
| Savić, N; Sciancalepore, M | 1 |
| Jiang, L; Kang, J; Nedergaard, M; Xu, J | 1 |
| Bear, MF; Huber, KM; Roder, JC | 1 |
| Averill, DB; Li, DP; Pan, HL | 1 |
| Akaike, N; Katsurabayashi, S; Kiyosawa, A; Pang, ZP | 1 |
| Kazuta, Y; Kohsaka, S; Kudo, Y; Matsuda, A; Mishina, M; Nakajima-Iijima, S; Nakamura, T; Shuto, S; Uchino, S; Watanabe, W | 1 |
| Alcocer, I; Bermúdez-Rattoni, F; Escobar, ML | 1 |
| Lei, S; McBain, CJ | 1 |
| Genever, PG; Gu, Y; Publicover, SJ; Skerry, TM | 1 |
| Freeman, FM; Rutter, AR; Stephenson, FA | 1 |
| Behnisch, T; Jäger, T; Reymann, KG | 1 |
| Wu, E | 1 |
| Gu, JG; Nakatsuka, T; Papke, R; Takeda, D | 1 |
| Gao, BX; Hinckley, C; Ziskind-Conhaim, L | 1 |
| Baxi, S; Evans, C; Irnaten, M; Mendelowitz, D; Venkatesan, P; Wang, J; Wang, X | 1 |
| Ammassari-Teule, M; Bernardi, G; Berretta, N; Geracitano, R; Guatteo, E; Longone, P; Mercuri, NB; Paolucci, E; Prisco, S; Zona, C | 1 |
| Chen, A; Hough, CJ; Li, H | 1 |
| Li, Y; Li, YF; Wu, LJ; Xu, L; Xu, TL | 1 |
| Ahmed, TM; Fujii, S; Kato, H; Kuroda, Y; Mikoshiba, K | 1 |
| Alreja, M; Hajszan, T; Leranth, C; Wu, M | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Rieke, F; Sampath, AP | 1 |
| Inoue, M; Kawamura, Y; Kudo, Y; Manita, S; Miyakawa, H; Nakamura, T | 1 |
| Chattarji, S; Choi, SY; Hayashi, ML; Jung, HY; Kirkwood, A; Lee, HK; Rao, BS; Tonegawa, S; Zhang, D | 1 |
| Duvoisin, RM; Grandes, P; Kushmerick, C; Price, GD; Puente, N; Renden, R; Taschenberger, H; von Gersdorff, H; Wadiche, JI | 1 |
| Cummings, DM; Milner, AJ; Murphy, KP; Spencer, JP | 1 |
| Belichenko, PV; Epstein, CJ; Kleschevnikov, AM; Malenka, RC; Mobley, WC; Villar, AJ | 1 |
| Arvanian, VL; Mendell, LM; Motin, V | 1 |
| Arif, M; Dionísio, JC; Matias, CM; Quinta-Ferreira, ME | 1 |
| Breustedt, J; Schmitz, D | 1 |
| Concas, A; Marino, G; Minei, R; Pierobon, P; Porcu, P; Sogliano, C; Tino, A; Tortiglione, C | 1 |
| Bonhoeffer, T; Finski, A; Lohmann, C | 1 |
| Hinckley, C; Seebach, B; Ziskind-Conhaim, L | 1 |
| Gillespie, DC; Kandler, K; Kim, G | 1 |
| Hashikawa, T; Hayashi, Y; Kobayashi, S; Miyawaki, A; Nagai, T; Nakagawa, T; Neve, RL; Okamoto, K; Takao, K | 1 |
| Foley, CM; Hasser, EM; Hay, M; Mueller, PJ; Vogl, HW | 1 |
| O'Connor, DH; Wang, SS; Wittenberg, GM | 1 |
| Knöpfel, T; Mutoh, H; Yuan, Q | 1 |
| Gu, Q; Yang, B | 1 |
| Gall, CM; Lin, CY; Lynch, G | 1 |
| Frondaroli, A; Grassi, S; Pettorossi, VE | 1 |
| Manahan-Vaughan, D; Pöschel, B | 1 |
| Brose, N; Gibson, HE; Jones, S; Morton, AJ; Reim, K | 1 |
| Hsu, KS; Huang, CC | 2 |
| Chen, YH; Li, KY; Sun, FY; Wang, JJ | 1 |
| Bayer, KU; De Koninck, P; LeBel, E; McDonald, GL; O'Leary, H; Schulman, H | 1 |
| Chen, HK; Su, CK | 1 |
| Dobrunz, LE; McCutchen, E; McMahon, LL; Scheiderer, CL | 1 |
| Lu, Y | 1 |
| Bustamante, J; Igartua, I; Solís, JM | 1 |
| El-Husseini, A; Li, B; Raymond, LA; Sornarajah, L; Sutton, C; Vasuta, OC; Zhang, L | 1 |
| Chen, L; Han, TZ; Jiang, ML | 1 |
| Farb, DH; Gibbs, TT; Whittaker, MT | 1 |
| Faria, LC; Fuortes, MG; Merlin, LR | 1 |
| Deshpande, SB; Gupta, R | 1 |
| Antri, M; Dubuc, R; Fénelon, K | 1 |
| Bolshakov, VY; Kang, JS; Krupa, B; Li, Y; Liu, G | 1 |
| Chen, T; Li, X; Mercaldo, V; Shang, Y; Wang, H; Zhuo, M | 1 |
| Hagena, H; Manahan-Vaughan, D | 1 |
| Dringenberg, HC; Hager, AM | 1 |
| Fujii, S; Kuroda, Y; Mikoshiba, K; Yamazaki, Y | 1 |
| Chari, M; Cheung, GW; Kokorovic, A; Lai, TY; Lam, CK; Lam, TK; Su, BB; Wang, PY; Yang, CS | 1 |
| Colombari, E; Menani, JV; Moreira, TS; Takakura, AC | 1 |
| Imoto, K; Miyata, M; Nagumo, Y; Takeuchi, Y | 1 |
| Chen, G; Ebner, TJ; Gao, W; Wang, X | 1 |
| Menzler, J; Zeck, G | 1 |
| Moreira, TS; Takakura, AC | 1 |
| Aihara, T; Fujii, S; Fujiwara, H; Goto, J; Kaneko, K; Mikoshiba, K; Sugihara, T; Sugita, M; Yamazaki, Y | 1 |
| Chen, Z; Ji, F; Liu, SY; Lu, W; Ren, SQ; Yao, W; Zhang, N; Zhang, XY | 1 |
| Kumar, SS; Pilli, J | 1 |
| Fontanini, A; Maffei, A; Wang, L | 1 |
| Li, YH; Wang, J | 1 |
| Colbert, CM; Eskin, A; Pita-Almenar, JD; Zou, S | 1 |
| Agovic, MS; Banerjee, SP; Chan, CY; Friedman, E; Ho, I; Shah, SM; Sun, HS | 1 |
| Guilarte, TR; Kang, J; Kang, N; Peng, H; Stanton, PK; Yu, Y | 1 |
| Cao, J; Duan, TT; Jing, L; Xu, L; Yuan, Q; Zhou, QX; Zhu, YY | 1 |
| Antkowiak, B; Eckle, VS | 1 |
| Allen, PD; DiGiacomo, RR; Forsythe, ID; Jalabi, W; Kopp-Scheinpflug, C; Maricich, SM; Schiavon, E | 1 |
| Dudka, J; Oniszczuk, T; Poleszak, E; Serefko, A; Szopa, A; Wlaź, P; Wośko, S; Wróbel, A | 1 |
| Deng, S; Ding, J; Ge, WH; Huang, C; Li, F; Li, WG; Nie, YZ; Peng, Z; Xie, Y; Xu, TL | 1 |
| Aksoy-Aksel, A; Manahan-Vaughan, D | 1 |
| Bostrom, CA; Chiu, C; Chiu, J; Christie, BR; Eadie, BD; Fontaine, CJ; Ghilan, M; Hryciw, BN; Meconi, A; Sawchuk, S; Truesdell, A; Truesdell, E; Wortman, RC; Yau, SY | 1 |
| Acton, D; Miles, GB | 1 |
| Collingridge, GL; Jia, Z; Leung, C; Liu, A; Meng, Y; Park, P; Qi, J; Xia, S; Xie, W; Zhou, Z | 1 |
| Destreel, G; Engel, D; Seutin, V | 1 |
262 other study(ies) available for 2-amino-5-phosphonovalerate and glycine
| Article | Year |
|---|---|
Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Iodine Radioisotopes; Kinetics; Male; Neurotoxins; Polyamines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Spermine; Synaptic Membranes; Wasp Venoms | 1991 |
L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Female; Glutamates; Glycine; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Pregnancy; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1992 |
Serotonin1A facilitation of frog motoneuron responses to afferent stimuli and to N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; Animals; Electric Stimulation; Evoked Potentials; Glycine; In Vitro Techniques; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rana pipiens; Serotonin; Spinal Cord; Spinal Nerve Roots; Tetrahydronaphthalenes; Tetrodotoxin; Tropanes | 1992 |
L-homocysteic acid selectively activates N-methyl-D-aspartate receptors of rat retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Glycine; Homocysteine; Kynurenic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Stimulation, Chemical | 1992 |
Administration of AP5, a glutamate antagonist, unmasks glycine analgesic actions in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Electroshock; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Injections, Spinal; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Vocalization, Animal | 1992 |
In vitro and in vivo characterization of the NMDA receptor-linked strychnine-insensitive glycine site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Strychnine | 1992 |
Differential effects of neuroexcitatory amino acids on corticotropin-releasing hormone-41 and vasopressin release from rat hypothalamic explants.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Corticotropin-Releasing Hormone; Glycine; Hypothalamus; Kainic Acid; Magnesium; Male; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
NMDA receptor mediates dopamine release in the striatum of unanesthetized rats as measured by brain microdialysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Brain Chemistry; Corpus Striatum; Dialysis; Dopamine; Glycine; Kynurenic Acid; Magnesium; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1992 |
3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cycloleucine; Egtazic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Oocytes; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Resorcinols; RNA, Messenger; Xenopus | 1992 |
Fast inhibitory postsynaptic potentials and responses to inhibitory amino acids of sympathetic preganglionic neurons in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Bicuculline; Cats; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Glycine; Membrane Potentials; Naloxone; Neurons; Phentolamine; Quinoxalines; Spinal Cord; Strychnine; Synapses | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
L-phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes.
Topics: 2-Amino-5-phosphonovalerate; Alzheimer Disease; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glycine; Kainic Acid; N-Methylaspartate; Phosphoserine; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Electrophysiological evidence for the presence of NMDA receptors in the guinea pig cochlea.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Animals; Auditory Pathways; Cochlea; Cochlear Microphonic Potentials; Electrophysiology; Female; Glycine; Guinea Pigs; Magnesium; Male; N-Methylaspartate; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate | 1991 |
Modulation of neuropathic pain behavior in rats by spinal disinhibition and NMDA receptor blockade of injury discharge.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dizocilpine Maleate; Electric Stimulation; Glutamates; Glutamic Acid; Glycine; Injections, Spinal; Male; Pain; Peripheral Nerve Injuries; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine | 1991 |
Synaptic responses of guinea pig and rat central amygdala neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine; Amino Acids; Amygdala; Animals; Baclofen; Electric Stimulation; Electrodes; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Male; Neuromuscular Depolarizing Agents; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Synapses | 1991 |
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Biguanides; Binding, Competitive; Biogenic Polyamines; Biotransformation; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Excitatory and inhibitory autaptic currents in isolated hippocampal neurons maintained in cell culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium Chloride; Cells, Cultured; Electric Conductivity; Electric Stimulation; Electrophysiology; Glycine; Hippocampus; Kynurenic Acid; Magnesium Chloride; Membrane Potentials; Neuroglia; Neurons; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Strychnine | 1991 |
Structure-activity analysis of binding kinetics for NMDA receptor competitive antagonists: the influence of conformational restriction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Electrophysiology; Glycine; Hippocampus; Kinetics; Mice; Models, Biological; Molecular Conformation; Neurons; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship | 1991 |
N-methyl-D-aspartate and aspartate raise the cytosolic free calcium concentration by acting upon receptors transiently expressed on immature cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebellum; Cytosol; Gallopamil; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Purkinje Cells; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
An arthropod NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Astacoidea; Cesium; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Immunoenzyme Techniques; Interneurons; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1991 |
Polyamine effects upon N-methyl-D-aspartate receptor functioning: differential alteration by glutamate and glycine site antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Kinetics; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine | 1991 |
Localization of NMDA and AMPA receptors in rat barrel field.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Cerebral Cortex; Glycine; Ibotenic Acid; Male; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine; Tritium | 1991 |
Stimulation of noradrenaline release in the cerebral cortex via presynaptic N-methyl-D-aspartate (NMDA) receptors and their pharmacological characterization.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1991 |
Proteolytic enzymes do not destroy the N-methyl-D-aspartate (NMDA) sensitivity of acutely isolated hippocampal CA1 and CA3 neurons from postnatal rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Cell Separation; Dose-Response Relationship, Drug; Drug Synergism; Electric Conductivity; Glycine; Hippocampus; Ion Channels; Magnesium; N-Methylaspartate; Neurons; Peptide Hydrolases; Rats | 1990 |
Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Cells, Cultured; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ion Channels; Kinetics; Kynurenic Acid; Models, Neurological; Piperazines; Receptors, N-Methyl-D-Aspartate | 1991 |
Desensitization of N-methyl-D-aspartate receptors in neurons dissociated from adult rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Glycine; Hippocampus; In Vitro Techniques; Ion Channels; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Behavioral sensitization to kainic acid and quisqualic acid in mice: comparison to NMDA and substance P responses.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Capsaicin; Concanavalin A; Drug Tolerance; GABA Antagonists; Glycine; Injections, Spinal; Kainic Acid; Mice; N-Methylaspartate; Quisqualic Acid; Spinal Cord; Substance P | 1991 |
Acetylcholine release from the rabbit retina mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Convulsants; Dizocilpine Maleate; Glycine; In Vitro Techniques; Light; Magnesium; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1991 |
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Female; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Social Isolation; Vocalization, Animal | 1990 |
Pharmacological properties of the N-methyl-D-aspartate receptor system coupled to the evoked release of gamma-[3H] aminobutyric acid from striatal neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Mice; Neurons; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Quisqualate activates N-methyl-D-aspartate receptor channels in hippocampal neurons maintained in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Electric Stimulation; Glycine; Hippocampus; Indoles; Ion Channel Gating; N-Methylaspartate; Neural Conduction; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Aspartic Acid; Cells, Cultured; Glycine; Hippocampus; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Osmolar Concentration; Piperazines | 1990 |
Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebellum; Electric Conductivity; Female; Glycine; Guinea Pigs; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Phencyclidine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1990 |
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Glycine synergistically potentiates the enhancement of LTP induced by a sulfhydryl reducing agent.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dithiothreitol; Drug Synergism; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine | 1990 |
Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Kynurenic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Degeneration; Neurons; Oocytes; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Taurine; Xenopus | 1990 |
Glycine facilitates induction of long-term potentiation of evoked potential in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Time Factors | 1990 |
A topological model of the NMDA-glycine receptor model.
Topics: 2-Amino-5-phosphonovalerate; Glutamates; Glutamic Acid; Glycine; Models, Molecular; N-Methylaspartate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Spinal neuronal pathology associated with continuous intrathecal infusion of N-methyl-D-aspartate in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glycine; Infusions, Parenteral; Magnesium Sulfate; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord | 1990 |
Ethanol inhibits NMDA-stimulated neurite growth by sensory neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Chick Embryo; Ethanol; Ganglia, Spinal; Glycine; Kynurenic Acid; Magnesium; N-Methylaspartate; Neurites; Neurons, Afferent | 1990 |
Ethanol inhibits N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat cortical slices.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Culture Techniques; Ethanol; Glycine; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin; Valine | 1990 |
Differential modulation of the associated glycine recognition site by competitive N-methyl-D-aspartate receptor antagonists.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Glycine; Male; N-Methylaspartate; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
Applications of quantitative measurements for assessing glutamate neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Glycine; Hippocampus; In Vitro Techniques; Ion Channels; Magnesium; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Biexponential kinetics of [3H]MK-801 binding: evidence for access to closed and open N-methyl-D-aspartate receptor channels.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glycine; In Vitro Techniques; Ion Channels; Kinetics; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Synaptosomes; Valine | 1989 |
Long-lasting physiological effects of bath applied N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Electric Stimulation; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Spermine; Time Factors; Valine | 1989 |
Glycine and kynurenate modulate the glutamate receptors in the myenteric plexus and in cortical membranes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Cerebral Cortex; Glycine; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Myenteric Plexus; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Glycine potentiates NMDA responses in rat hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glycine; Hippocampus; Humans; N-Methylaspartate; Rats; Valine | 1989 |
Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Electrophysiology; Glutamates; Glycine; Hippocampus; Histocytochemistry; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Excitatory amino acid-receptor-mediated EPSPs in rat dorsolateral septal nucleus neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Septal Nuclei; Synaptic Transmission | 1989 |
Effects of depressant amino acids and antagonists on an in vitro spinal cord preparation from the adult rat.
Topics: Action Potentials; Amino Acids; Animals; Bicuculline; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Magnesium; Picrotoxin; Piperazines; Rats; Spinal Cord; Strychnine; Synapses; Taurine; Valine | 1989 |
Mode of binding of [3H]dibenzocycloalkenimine (MK-801) to the N-methyl-D-aspartate (NMDA) receptor and its therapeutic implication.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Properties of glycine-activated conductances in rat brain neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; beta-Alanine; Glycine; Hippocampus; In Vitro Techniques; Male; Medulla Oblongata; Neural Conduction; Neurons; Rats; Taurine; Valine | 1988 |
Glycine reverses antagonism of N-methyl-D-aspartate (NMDA) by 1-hydroxy-3-aminopyrrolidone-2 (HA-966) but not by D-2-amino-5-phosphonovalerate (D-AP5) on rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Evoked Potentials; Glycine; In Vitro Techniques; N-Methylaspartate; Pyrrolidinones; Rats; Valine | 1988 |
Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cations, Divalent; Cells, Cultured; Glycine; Hippocampus; Ketamine; Kynurenic Acid; Magnesium; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Zinc | 1988 |
Glycine potentiates strychnine-induced convulsions: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Drug Synergism; Glycine; Injections, Spinal; Mice; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Strychnine; Valine | 1988 |
Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ganglia, Spinal; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Functional transmitters at retinal ganglion cells in the cat.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Action Potentials; Animals; Aspartic Acid; Bicuculline; Cats; Dihydro-beta-Erythroidine; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Neurotransmitter Agents; Retina; Retinal Ganglion Cells; Strychnine; Valine | 1983 |
Calcium-dependent glutamate release during neuronal development and synaptogenesis: different involvement of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Cells, Cultured; Fetus; Glutamic Acid; Glycine; Hippocampus; Kinetics; Magnesium; N-Methylaspartate; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Rats; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Synapses; Time Factors | 1995 |
Neurochemical and behavioural investigations of the NMDA receptor-associated glycine site in the rat striatum: functional implications for treatment of parkinsonian symptoms.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding, Competitive; Corpus Striatum; Dose-Response Relationship, Drug; Glycine; Locomotion; Male; Oxidopamine; Parkinson Disease; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; DNA, Neoplasm; Glutamates; Glutamic Acid; Glycine; Humans; Ion Channels; Kinetics; Magnesium; Membrane Potentials; Molecular Sequence Data; N-Methylaspartate; Neurons; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; RNA, Neoplasm; Sequence Homology, Amino Acid; Teratoma; Tumor Cells, Cultured | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
Pharmacological characterization of the N-methyl-D-aspartate (NMDA) receptor recognition site in porcine cerebral cortical membranes using [3H]-CGP 39653.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Glycine; Hydrogen-Ion Concentration; Kinetics; Rats; Receptors, N-Methyl-D-Aspartate; Swine; Tritium | 1995 |
Antagonists of the metabotropic glutamate receptor do not prevent induction of long-term potentiation in the dentate gyrus of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Long-Term Potentiation; Male; Neural Pathways; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1995 |
Potent, orally active, competitive N-methyl-D-aspartate (NMDA) receptor antagonists are substrates for a neutral amino acid uptake system in Chinese hamster ovary cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport Systems; Amino Acids; Animals; Binding, Competitive; Biphenyl Compounds; Carrier Proteins; CHO Cells; Cricetinae; Glutamic Acid; Glycine; Kinetics; Magnetic Resonance Spectroscopy; Membranes; Models, Molecular; Molecular Conformation; Phenylalanine; Propionates; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synaptosomes; Tritium | 1995 |
Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Glycine; Hippocampus; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1994 |
An investigation of depotentiation of long-term potentiation in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Benzoates; Electric Stimulation; Female; Glycine; Hippocampus; Long-Term Potentiation; Nimodipine; Nitroarginine; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Time Factors | 1994 |
Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Cyclic AMP; Glycine; Hippocampus; Hydrolysis; Long-Term Potentiation; Male; Motor Activity; Pharmaceutical Vehicles; Phosphatidylinositols; Rats; Rats, Wistar; Reaction Time; Receptors, Metabotropic Glutamate; Stereoisomerism; Synaptic Transmission | 1995 |
NMDA-mediated potentiation of the afferent synapse in the inner ear.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Amplifiers, Electronic; Animals; Dizocilpine Maleate; Electrophysiology; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Physical Stimulation; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synapses; Vestibule, Labyrinth | 1994 |
Volatile anesthetics inhibit NMDA-stimulated 45Ca uptake by rat brain microvesicles.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Calcium; Calcium Radioisotopes; Dizocilpine Maleate; Enflurane; Glycine; Halothane; Kinetics; Male; Microcirculation; N-Methylaspartate; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Synaptic desensitization of NMDA receptors by calcineurin.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Calcineurin; Calcium; Calmodulin-Binding Proteins; Cells, Cultured; Egtazic Acid; Electric Stimulation; Glycine; Hippocampus; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphorylation; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1995 |
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine | 1993 |
nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine | 1993 |
Potent analgesia induced in rats by combined action at PCP and polyamine recognition sites of the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Drug Combinations; Drug Synergism; Glycine; Injections, Spinal; Male; Nociceptors; Phencyclidine; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermine | 1993 |
[3H]CGP 39653 binding to the agonist site of the N-methyl-D-aspartate receptor is modulated by Mg2+ and polyamines independently of the arcaine-sensitive polyamine site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Glycine; Kinetics; Magnesium; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium | 1994 |
Adaptation of the NMDA receptor in rat cortex following chronic electroconvulsive shock or imipramine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Electroshock; Glycine; Imipramine; In Vitro Techniques; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Mechanisms of interaction of Escherichia coli threonine synthase with substrates and inhibitors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Carbon-Oxygen Lyases; Escherichia coli; Glycine; Homoserine; Kinetics; Lyases; Organophosphorus Compounds; Spectrophotometry; Substrate Specificity | 1994 |
Evidence for NMDA receptor in the afferent synaptic transmission of the vestibular system.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Animals; Glycine; Hair Cells, Auditory; In Vitro Techniques; Kynurenic Acid; Magnesium; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Receptors, N-Methyl-D-Aspartate; Semicircular Canals; Synapses; Synaptic Transmission; Vestibule, Labyrinth | 1994 |
Complex allosteric modulation of the binding of the NMDA receptor antagonist [3H]CGP39653.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Biguanides; Binding Sites; Glycine; In Vitro Techniques; Kynurenic Acid; Male; Piperidines; Prosencephalon; Putrescine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 1994 |
Modulation of muscarinic cholinoceptor-stimulated inositol 1,4,5-trisphosphate accumulation by N-methyl-D-aspartate in neonatal rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Carbachol; Cerebral Cortex; Dizocilpine Maleate; Female; Glycine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Magnesium; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Muscarinic | 1994 |
NMDA receptor function is enhanced in the hippocampus of aged rats.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Kinetics; Male; Organ Specificity; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Tritium | 1994 |
Preferential induction by stress of the N-methyl-D-aspartate recognition domain in discrete structures of rat brain.
Topics: 2-Amino-5-phosphonovalerate; Adrenal Cortex Hormones; Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Cerebellum; Corpus Striatum; Cycloheximide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glycine; Hypothalamus; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Stress, Physiological; Tritium | 1994 |
Transient ischemia causes a reduction of Mg2+ blockade of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium Channels; Cell Death; Electrophysiology; Glycine; Ischemic Attack, Transient; Magnesium; Male; Membrane Potentials; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Long-lasting potentiation of synaptic transmission in the Schaffer collateral-commissural pathway of the guinea pig hippocampus by activation of postsynaptic N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Spermine; Synapses; Synaptic Transmission | 1993 |
Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; Molecular Sequence Data; Neurons; Neurotoxins; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Strychnine; Time Factors | 1993 |
Modulation of neuronal migration by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Calcium; Cell Movement; Cerebellum; Dizocilpine Maleate; Egtazic Acid; Glutamates; Glutamic Acid; Glycine; Magnesium; Mice; N-Methylaspartate; Neurons; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1993 |
Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Female; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1993 |
Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Brain; Dizocilpine Maleate; Drug Administration Schedule; Glycine; Imipramine; In Vitro Techniques; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate | 1993 |
Pharmacological isolation and characterization of NMDA receptor-mediated synaptic potential in the dentate gyrus of rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Allosteric modulation of [3H]CGP 39653 binding by glycine in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Glycine; Kinetics; Kynurenic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Tritium | 1993 |
Recordings of glutamate receptor channels in isolated postsynaptic densities.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glutamates; Glutamic Acid; Glycine; Histocytochemistry; In Vitro Techniques; Long-Term Potentiation; Neurotransmitter Agents; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Telencephalon | 1993 |
Context-dependent synaptic action of glycinergic and GABAergic inputs in the dorsal cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Cochlear Nucleus; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Membrane Potentials; Mice; Mice, Inbred CBA; Muscimol; Neural Inhibition; Neurons; Quinoxalines; Synaptic Transmission; Time Factors | 1996 |
Generation and characterisation of stable cell lines expressing recombinant human N-methyl-D-aspartate receptor subtypes.
Topics: 2-Amino-5-phosphonovalerate; Aminoquinolines; Animals; Binding Sites; Blotting, Northern; Cell Line; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Expression; Glutamine; Glycine; Humans; Mice; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Tritium | 1996 |
Presynaptic long-term depression at the hippocampal mossy fiber-CA3 synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Benzoates; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred ICR; Neuronal Plasticity; Nicardipine; Pyramidal Cells; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1996 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
Diffusion, not uptake, limits glycine concentration in the synaptic cleft.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Diffusion; Electric Conductivity; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Goldfish; Nerve Net; Neural Inhibition; Neurons; Stimulation, Chemical; Synapses; Temperature | 1996 |
Use of subunit-specific antisense oligodeoxynucleotides to define developmental changes in the properties of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Base Sequence; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kynurenic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oligonucleotides, Antisense; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus laevis | 1996 |
Properties of spontaneous inhibitory synaptic currents in cultured rat spinal cord and medullary neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neural Inhibition; Neurons; Normal Distribution; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission; Tetrodotoxin | 1996 |
Ion channel properties of a protein complex with characteristics of a glutamate/N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Brain; Calcium; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channels; Lipid Bilayers; Liposomes; Patch-Clamp Techniques; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1996 |
Long-term depression at the medial perforant path-granule cell synapse in developing rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Calcium Channel Blockers; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Male; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Stimulation of metabotropic glutamate receptors in the dorsomedial hypothalamus elevates heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cycloleucine; Dose-Response Relationship, Drug; Glycine; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Tachycardia | 1996 |
Extracts from rhizomes of Cyperus articulatus (Cyperaceae) displace [3H]CGP39653 and [3H]glycine binding from cortical membranes and selectively inhibit NMDA receptor-mediated neurotransmission.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Binding, Competitive; Cerebral Cortex; Excitatory Amino Acid Antagonists; Glycine; Male; Membranes; Piperazines; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tritium | 1996 |
Postsynaptic glutamate uptake in rat cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channel Gating; Kynurenic Acid; Membrane Potentials; Monosaccharide Transport Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin | 1996 |
Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzoates; Colforsin; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Interneurons; Kinetics; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tetrodotoxin | 1996 |
Effect of glutamate receptor phosphorylation by endogenous protein kinases on electrical activity of isolated postsynaptic densities of rat cortex and hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Cerebral Cortex; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Kainic Acid; Long-Term Potentiation; Magnesium; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Protein Kinases; Quisqualic Acid; Rats; Receptors, Glutamate; Synapses | 1997 |
DCG-IV inhibits synaptic transmission by activation of NMDA receptors in area CA1 of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cyclopropanes; Evoked Potentials; Glycine; Purinergic P1 Receptor Antagonists; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Xanthines | 1997 |
Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Binding Sites; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Ion Channel Gating; Models, Molecular; Molecular Sequence Data; Piperazines; Receptors, N-Methyl-D-Aspartate; Sequence Alignment; Sequence Homology, Amino Acid | 1997 |
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Animals; Cells, Cultured; Cerebral Cortex; Child; Dizocilpine Maleate; Embryo, Mammalian; Evoked Potentials; Glycine; Homocysteine; Humans; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Responses of Bergmann glia and granule neurons in situ to N-methyl-D-aspartate, norepinephrine, and high potassium.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Animals; Benzoates; Calcium; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Fluorescent Dyes; Glycine; N-Methylaspartate; Neuroglia; Neurons; Norepinephrine; Organic Chemicals; Potassium; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1997 |
Glycine causes increased excitability and neurotoxicity by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzoxazines; Cell Death; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neurons; Neurotoxins; Organ Culture Techniques; Oxazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
A partial agonist model used in the allosteric modulation of the NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Models, Biological; Protein Binding; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Potentiation of synaptic transmission in the rat dentate gyrus in vitro by (S)-3,5-dihydroxyphenylglycine ((S)-DHPG).
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Rats; Resorcinols; Stimulation, Chemical; Synaptic Transmission | 1997 |
Is activation of the metabotropic glutamate receptors impaired in the hippocampal CA1 area of the aged rat?
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1997 |
Crossed rhythmic synaptic input to motoneurons during selective activation of the contralateral spinal locomotor network.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Chlorides; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Glycine Agents; Locomotion; Motor Neurons; N-Methylaspartate; Neural Inhibition; Periodicity; Rats; Rats, Wistar; Receptors, GABA-A; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine; Synaptic Transmission | 1997 |
Blockade and recovery of spontaneous rhythmic activity after application of neurotransmitter antagonists to spinal networks of the chick embryo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Chick Embryo; Cholinergic Antagonists; Dihydro-beta-Erythroidine; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Glycine; Glycine Agents; Mecamylamine; Motor Neurons; Neuronal Plasticity; Neurotransmitter Agents; Nicotinic Antagonists; Periodicity; Spinal Cord; Strychnine | 1998 |
Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Arachidonic Acid; Biomarkers; Cells, Cultured; Cerebellum; Dibucaine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flow Cytometry; Fluorescent Dyes; Glycine; Intracellular Membranes; Kynurenic Acid; Membrane Potentials; Mitochondria; N-Methylaspartate; Piperidines; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamine 123; Rhodamines; Sulfonamides | 1997 |
Glycine increases arterial pressure and augments NMDA-induced pressor responses in the dorsomedial and ventrolateral medulla of cats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cats; Dorsomedial Hypothalamic Nucleus; Drug Synergism; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Glycine; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Ventromedial Hypothalamic Nucleus | 1997 |
Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Calcium; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Fetus; Glycine; Humans; Mice; N-Methylaspartate; Neocortex; Neurites; Neurons; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Steroid 17-alpha-Hydroxylase | 1998 |
Adaptation of cortical NMDA receptors by chronic treatment with specific serotonin reuptake inhibitors.
Topics: 2-Amino-5-phosphonovalerate; Adaptation, Physiological; Animals; Binding, Competitive; Cerebral Cortex; Citalopram; Excitatory Amino Acid Antagonists; Fluoxetine; Glycine; Male; Mice; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors | 1998 |
Channel properties of NMDA receptors on magnocellular neuroendocrine cells cultured from the rat supraoptic nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Drug Synergism; Electric Conductivity; Excitatory Amino Acid Antagonists; Glycine; Immunohistochemistry; Ion Channels; Magnesium; Neurosecretory Systems; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus | 1998 |
Olfactory reciprocal synapses: dendritic signaling in the CNS.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Calcium; Calcium Channel Blockers; Calcium Channels; Dendrites; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Models, Neurological; Nifedipine; Olfactory Bulb; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Synaptic Transmission; Tetrodotoxin | 1998 |
Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclopropanes; Dipeptides; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Receptors, Metabotropic Glutamate | 1998 |
Progression of change in NMDA, non-NMDA, and metabotropic glutamate receptor function at the developing corticothalamic synapse.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Mice; Mice, Inbred ICR; Nerve Fibers; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Thalamus | 1998 |
Subtype-specific involvement of metabotropic glutamate receptors in two forms of long-term potentiation in the dentate gyrus of freely moving rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gallopamil; Glycine; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 1998 |
Chronic dosing with 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, modulates NMDA inhibition of muscarinic-coupled PI hydrolysis in rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; In Vitro Techniques; Inositol; Kynurenic Acid; Male; Muscarinic Agonists; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Interaction of memantine and amantadine with agonist-unbound NMDA-receptor channels in acutely isolated rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Amantadine; Animals; Aspartic Acid; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Memantine; Membrane Potentials; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Spinal inputs from lateral columns to reticulospinal neurons in lampreys.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Brain Stem; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Isotonic Solutions; Lampreys; Locomotion; Magnesium; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Ringer's Solution; Spinal Cord; Synaptic Transmission | 1998 |
Slow oscillations (
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Age Factors; Animals; Benzoates; Bicuculline; Cardiovascular Agents; Cesium; Chlorides; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glycine; Hippocampus; Interneurons; Male; Membrane Potentials; Neural Pathways; Organ Culture Techniques; Patch-Clamp Techniques; Periodicity; Pyrimidines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Temperature; Xanthines | 1998 |
Prolonged activation of the N-methyl-D-aspartate receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzoates; Calcium; Cells, Cultured; Dizocilpine Maleate; Egtazic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Magnesium; Membrane Potentials; Microscopy, Confocal; Neurons; Nifedipine; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1998 |
Long-term potentiation in vivo increases rat hippocampal tenascin-C expression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Immunohistochemistry; In Situ Hybridization; Long-Term Potentiation; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Synaptic Transmission; Tenascin | 1998 |
Activation of metabotropic glutamate receptors is necessary for transneuronal regulation of ribosomes in chick auditory neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Chick Embryo; Cochlea; Cochlear Nerve; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Neurons, Afferent; Receptors, Metabotropic Glutamate; Ribosomes | 1998 |
Modulation of N-methyl-D-aspartate receptor function by glycine transport.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport Systems, Neutral; Animals; Bicuculline; Carrier Proteins; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Glycine Plasma Membrane Transport Proteins; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 1998 |
Noxious thermal stimulation of c-fos activity induced in rat lumbar spinal cord is reduced by AP-5 but not by glycine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Glycine; Hot Temperature; Immunohistochemistry; Injections, Spinal; Lumbosacral Region; Male; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
NMDA receptor characterization and subunit expression in rat cultured mesencephalic neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Gene Expression; Gene Expression Regulation, Developmental; Glycine; Memantine; Mesencephalon; N-Methylaspartate; Neurons; Nitrendipine; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA Splicing; RNA, Messenger | 1999 |
Long-term suppression of synaptic transmission by tetanization of a single pyramidal cell in the mouse hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Phosphinic Acids; Propanolamines; Pyramidal Cells; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Group I metabotropic glutamate receptors mediate phospholipase D stimulation in rat cultured astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Benzoates; Carcinogens; Cerebellum; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neurons; Neuroprotective Agents; Norepinephrine; Phospholipase D; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathomimetics; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1999 |
Properties of NMDA receptors in rat spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Magnesium; Male; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Ferrous iron modulates quinolinate-mediated [3H]MK-801 binding to rat brain synaptic membranes in the presence of glycine and spermidine.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Binding Sites; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ferrous Compounds; Glutamic Acid; Glycine; Inhibitory Concentration 50; Kynurenic Acid; Male; Quinolinic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Synaptic Membranes | 1999 |
Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Animals, Suckling; Bicuculline; Cycloheximide; Darkness; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kynurenic Acid; Light; Male; Models, Neurological; Nerve Tissue Proteins; Neuronal Plasticity; Optic Nerve; Photic Stimulation; Piperidines; Protein Synthesis Inhibitors; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Synapses; Vision, Ocular; Visual Cortex; Zinc | 1999 |
Role of glutamate receptor subtypes in the lamprey respiratory network.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kynurenic Acid; Lampreys; Neurons; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Respiration | 1999 |
Input-and layer-dependent synaptic plasticity in the rat perirhinal cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Long-Term Potentiation; Male; Neocortex; Neuronal Plasticity; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Junctional versus extrajunctional glycine and GABA(A) receptor-mediated IPSCs in identified lamina I neurons of the adult rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Evoked Potentials; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Strychnine; Sucrose; Tetrodotoxin | 1999 |
Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Benzoates; Calcium; Cell Communication; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Membrane Potentials; Neuroimmunomodulation; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thapsigargin | 1999 |
Group I metabotropic glutamate receptors mediate an inward current in rat substantia nigra dopamine neurons that is independent from calcium mobilization.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Chromones; Cycloleucine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Microscopy, Fluorescence; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Substantia Nigra; Tetrodotoxin; Thapsigargin | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Physiological evidence for ionotropic and metabotropic glutamate receptors in rat taste cells.
Topics: 2-Amino-5-phosphonovalerate; 8-Bromo Cyclic Adenosine Monophosphate; Aminobutyrates; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Taste Buds | 1999 |
Excitatory and inhibitory synaptic inputs shape the discharge pattern of pump neurons of the nucleus tractus solitarii in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Neural Inhibition; Neurons; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Strychnine; Synapses | 1999 |
Developmental changes in the neurotransmitter regulation of correlated spontaneous retinal activity.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Cholinergic Fibers; Excitatory Amino Acid Antagonists; Ferrets; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glycine Agents; Interneurons; Periodicity; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Synaptic Transmission; Vision, Ocular; Visual Pathways | 2000 |
NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Antimetabolites; Antipsychotic Agents; Binding Sites; Cycloleucine; Cycloserine; Disease Models, Animal; Dopamine Agents; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hallucinogens; Locomotion; Male; Phencyclidine; Phthalazines; Protein Structure, Tertiary; Psychotic Disorders; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 1999 |
Actions of midazolam on GABAergic transmission in substantia gelatinosa neurons of adult rat spinal cord slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Membrane Potentials; Midazolam; Muscimol; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord; Substantia Gelatinosa; Synaptic Transmission | 2000 |
High Ca(2+)/low Mg(2+) solution induces long-term depression in rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Calcium; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Magnesium; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sirolimus; Solutions; Tacrolimus; Verapamil | 2000 |
Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kindling, Neurologic; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Phenylacetates; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Sodium; Tetrodotoxin; Up-Regulation | 2000 |
Long-term potentiation of primary afferent neurotransmission at trigeminal synapses of juvenile rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Chelating Agents; Egtazic Acid; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Trigeminal Nuclei | 2000 |
N-methyl-D-aspartate enhancement of the glycine response in the rat sacral dorsal commissural neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Chloride Channels; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kinetics; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Spinal Cord | 2000 |
Modulation of synaptic transmission in the rat ventral septal area by the pharmacological activation of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cyclopropanes; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Methoxyhydroxyphenylglycol; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Septum of Brain; Synaptic Transmission | 2000 |
Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression; Glycine; Hippocampus; Interneurons; Neuroprotective Agents; Patch-Clamp Techniques; Periodicity; Picrotoxin; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Tetrodotoxin | 2000 |
Selective depolarization of interneurons in the early posttraumatic dentate gyrus: involvement of the Na(+)/K(+)-ATPase.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Benzoates; Bicuculline; Brain Injuries; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; In Vitro Techniques; Interneurons; Membrane Potentials; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Strophanthidin; Tetrodotoxin; Wounds, Nonpenetrating | 2000 |
Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine | 2000 |
The regulatory connection between the activity of granule cell NMDA receptors and dendritic differentiation of cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Calcium; Cell Count; Cell Differentiation; Cells, Cultured; Dendrites; Excitatory Amino Acid Antagonists; Glycine; Intracellular Fluid; N-Methylaspartate; Nitric Oxide; Purkinje Cells; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission | 2000 |
Elevation of intradendritic sodium concentration mediated by synaptic activation of metabotropic glutamate receptors in cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Image Processing, Computer-Assisted; Membrane Potentials; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Patch-Clamp Techniques; Picrotoxin; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Sodium; Synapses; Synaptic Transmission; Tetrodotoxin | 2000 |
Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesia.
Topics: 2-Amino-5-phosphonovalerate; Analgesia; Animals; Behavior, Animal; Binding Sites; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Injections, Spinal; Motor Activity; Nociceptors; Pain Measurement; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2000 |
Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Animals; Benzoates; Bungarotoxins; Calcium; Calcium Channel Blockers; Choline; Dihydro-beta-Erythroidine; Endoplasmic Reticulum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indoles; Insecticides; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Nicotine; Nicotinic Agonists; Nifedipine; Nootropic Agents; Patch-Clamp Techniques; Polyamines; Presynaptic Terminals; Receptors, Nicotinic; Substantia Nigra; Tetrodotoxin; Tyrosine 3-Monooxygenase | 2000 |
Generation and propagation of 4-AP-induced epileptiform activity in neonatal intact limbic structures in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Benzoates; Dizocilpine Maleate; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glutamate | 2000 |
Induction of locomotor sensitization by amphetamine requires the activation of NMDA receptors in the rat ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Benzoates; Central Nervous System Stimulants; Excitatory Amino Acid Antagonists; Glycine; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 2000 |
Molecular signalling pathways in the cerebral cortex are required for retrieval of one-trial avoidance learning in rats.
Topics: 2-Amino-5-phosphonovalerate; Adenylyl Cyclases; Animals; Avoidance Learning; Benzoates; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Entorhinal Cortex; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Functional Laterality; Glycine; Hippocampus; Injections; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2000 |
Quisqualate induces an inward current via mGluR activation in neocortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Guanosine Diphosphate; In Vitro Techniques; Membrane Potentials; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin; Thionucleotides | 2000 |
Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain Stem; Child, Preschool; Excitatory Amino Acid Antagonists; Female; Glycine; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn; Middle Aged; Neuroprotective Agents; Phencyclidine; Pregnancy; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Sudden Infant Death | 2000 |
Local calcium release in dendritic spines required for long-term synaptic depression.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Calcium Channels; Calcium Signaling; Cerebellum; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Intermediate Filament Proteins; Mice; Mice, Neurologic Mutants; Myosin Heavy Chains; Myosin Type V; Neural Inhibition; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Mutant Strains; Receptors, Cytoplasmic and Nuclear; Synaptic Transmission; Time | 2000 |
Temperature-dependent separation of a delayed-onset long-lasting enhancement mediated by coactivation of NMDA and metabotropic glutamate receptors following a transient exposure of extracellular high Ca(2+).
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Calcium; Cold Temperature; Cricetinae; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; Glycine; Hippocampus; In Vitro Techniques; Male; Mesocricetus; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Temperature | 2001 |
Stimulation of metabotropic but not ionotropic glutamatergic receptors in the nucleus accumbens is required for the D-amphetamine-induced release of functional dopamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Benzoates; Brain Chemistry; Central Nervous System Stimulants; Dextroamphetamine; Dopamine; Excitatory Amino Acid Antagonists; Glycine; Hyperkinesis; Male; Morphine; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Ventral Tegmental Area | 2001 |
Slow inhibitory potentials in the teleost Mauthner cell.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Chlorides; Escape Reaction; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Goldfish; Interneurons; Motor Neurons; Neural Inhibition; Patch-Clamp Techniques; Reaction Time; Strychnine; Tetrodotoxin; Zebrafish | 2001 |
NMDA-responsible, APV-insensitive receptor in cultured human astrocytes.
Topics: Astrocytes; Calcium; Cells, Cultured; Glial Fibrillary Acidic Protein; Glycine; GTP-Binding Proteins; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Peripheral group I metabotropic glutamate receptors modulate nociception in mice.
Topics: Animals; Chromones; Excitatory Amino Acid Antagonists; Glycine; Hindlimb; Hot Temperature; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain; Pain Measurement; Pyridines; Receptors, Metabotropic Glutamate; Valine | 2001 |
Allosteric modulation of [3H]-CGP39653 binding through the glycine site of the NMDA receptor: further studies in rat and human brain.
Topics: 2-Amino-5-phosphonovalerate; Aged; Animals; Autoradiography; Brain Chemistry; Excitatory Amino Acid Antagonists; Female; Glycine; Humans; In Vitro Techniques; Indoles; Male; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synaptic Membranes | 2001 |
Glutamate does not play a major role in controlling bone growth.
Topics: 2-Amino-5-phosphonovalerate; Alveolar Bone Loss; Amino Acid Transport System X-AG; Animals; Animals, Newborn; ATP-Binding Cassette Transporters; Biological Transport; Bone Diseases, Metabolic; Bone Remodeling; Bone Resorption; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Femur; Glutamic Acid; Glycine; Humerus; Mandible; Mice; Mice, Knockout; Models, Animal; N-Methylaspartate; Osteoblasts; Osteoclasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Aminobutyrates; Animals; Bicuculline; Drug Design; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Substantia Nigra; Xanthenes | 2001 |
Electrophysiological characterization of "giant" cells in stratum radiatum of the CA3 hippocampal region.
Topics: 2-Amino-5-phosphonovalerate; 3,3'-Diaminobenzidine; Action Potentials; Animals; Axons; Bicuculline; Calcium; Cesium; Chlorides; Choline; Cyclopropanes; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Immunoenzyme Techniques; Microscopy, Video; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2001 |
A kainate receptor increases the efficacy of GABAergic synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Benzodiazepines; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neurons; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Staurosporine; Synapses; Tetradecanoylphorbol Acetate; Tetrodotoxin | 2001 |
Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Long-Term Potentiation; Mice; Mice, Knockout; Neural Inhibition; Organ Culture Techniques; Rats; Rats, Long-Evans; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; RNA, Messenger; Stimulation, Chemical | 2001 |
Differential roles for glutamate receptor subtypes within commissural NTS in cardiac-sympathetic reflex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Blood Pressure; Bradykinin; Excitatory Amino Acid Antagonists; Glycine; Heart; Instillation, Drug; Kidney; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus; Sympathetic Nervous System | 2001 |
Nicotine facilitates glycine release in the rat spinal dorsal horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Bacterial Toxins; Bicuculline; Bungarotoxins; Calcium; Calcium Channels; Choline; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Marine Toxins; Mecamylamine; Microcystins; Nerve Endings; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Gelatinosa; Tetrodotoxin; Tropanes; Valine | 2001 |
Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of a novel antagonist PPDC.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Glycine; Hot Temperature; Piperidines; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
In vivo effects of intracortical administration of NMDA and metabotropic glutamate receptors antagonists on neocortical long-term potentiation and conditioned taste aversion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Benzoates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Male; Microinjections; N-Methylaspartate; Neocortex; Piperazines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Taste | 2002 |
Distinct NMDA receptors provide differential modes of transmission at mossy fiber-interneuron synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Chlorides; Cyclopropanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Mossy Fibers, Hippocampal; N-Methylaspartate; Patch-Clamp Techniques; Phenols; Piperidines; Polyamines; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2002 |
The NMDA type glutamate receptors expressed by primary rat osteoblasts have the same electrophysiological characteristics as neuronal receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Femur; Glycine; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Osteoblasts; Patch-Clamp Techniques; Perfusion; Rats; Receptors, N-Methyl-D-Aspartate | 2002 |
Further characterization of the molecular interaction between PSD-95 and NMDA receptors: the effect of the NR1 splice variant and evidence for modulation of channel gating.
Topics: 2-Amino-5-phosphonovalerate; Binding, Competitive; Cell Line; Dizocilpine Maleate; DNA, Recombinant; Excitatory Amino Acid Antagonists; Genetic Variation; Glutamic Acid; Glycine; Humans; Ion Channel Gating; Nerve Tissue Proteins; Prosencephalon; Receptors, N-Methyl-D-Aspartate | 2002 |
High frequency stimulation-induced dendritic calcium waves in rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Benzoates; Calcium; Calcium Signaling; Dendrites; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glycine; Hippocampus; In Vitro Techniques; Lidocaine; Male; Microscopy, Confocal; N-Methylaspartate; Neurons; Organic Chemicals; Rats; Rats, Wistar | 2002 |
Evidence against the presence of NMDA receptors at a central glutamatergic synapse in leeches.
Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Central Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kynurenic Acid; Leeches; Motor Neurons; N-Methylaspartate; Neurons, Afferent; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex; Synapses; Synaptic Transmission | 2002 |
Modulation of inhibitory synaptic activity by a non-alpha4beta2, non-alpha7 subtype of nicotinic receptors in the substantia gelatinosa of adult rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Alkaloids; Animals; Azocines; Choline; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Nicotine; Nicotinic Agonists; Nootropic Agents; Patch-Clamp Techniques; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substantia Gelatinosa; Synaptic Transmission | 2003 |
Ethanol dual modulatory actions on spontaneous postsynaptic currents in spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Central Nervous System Depressants; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Motor Neurons; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2003 |
Endogenous acetylcholine and nicotine activation enhances GABAergic and glycinergic inputs to cardiac vagal neurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Heart; Neostigmine; Neurons; Nicotine; Nicotinic Agonists; Parasympathetic Nervous System; Picrotoxin; Pyridazines; Rats; Strychnine; Synaptic Transmission; Vagus Nerve | 2003 |
Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY(93)-->ALA) mutation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Alanine; Animals; Avoidance Learning; Calcium; Cell Membrane; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Electric Stimulation; Genotype; Glycine; Gyrus Cinguli; Humans; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Motor Activity; Mutation; Neural Pathways; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinpirole; Superoxide Dismutase; Valine | 2003 |
Serotonin type II receptor activation facilitates synaptic plasticity via N-methyl-D-aspartate-mediated mechanism in the rat basolateral amygdala.
Topics: Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indophenol; Ketanserin; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Synaptic Transmission; Time Factors; Valine | 2003 |
Mechanisms of H+ modulation of glycinergic response in rat sacral dorsal commissural neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acids; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Neural Inhibition; Neurons; Protons; Rats; Rats, Wistar; Sacrococcygeal Region; Spinal Cord; Strychnine; Tetrodotoxin; Zinc | 2003 |
Cooperativity between activation of metabotropic glutamate receptors and NMDA receptors in the induction of LTP in hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Boron Compounds; Calcium; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Male; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Acyclovir; Animals; Animals, Newborn; Atropine; Bicuculline; Bungarotoxins; Carrier Proteins; Cell Count; Choline; Chromones; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Membrane Transport Proteins; Microscopy, Electron; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Septum of Brain; Synapses; Tetrodotoxin; Tubocurarine; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2003 |
Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclase Inhibitors; Amino Acids; Amino Acids, Dicarboxylic; Animals; Colforsin; Cyclopropanes; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Imines; In Vitro Techniques; Isoquinolines; Male; Picrotoxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Subthalamic Nucleus; Sulfonamides; Synaptic Transmission; Tetradecanoylphorbol Acetate; Xanthenes | 2003 |
Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Aminobutyrates; Animals; Binding Sites; Darkness; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Light; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Photons; Retina; Retinal Rod Photoreceptor Cells; Synapses; Synaptic Transmission; Valine; Xanthenes | 2004 |
Glutamate release increases during mossy-CA3 LTP but not during Schaffer-CA1 LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Colforsin; Coloring Agents; Cyclopropanes; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Magnesium; Male; Mossy Fibers, Hippocampal; Neuroglia; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Blotting, Northern; Blotting, Western; Dendrites; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Immunohistochemistry; In Situ Hybridization; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron; Models, Neurological; Nerve Tissue Proteins; Neurofilament Proteins; Neurons; p21-Activated Kinases; Prosencephalon; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Rats; Retention, Psychology; Silver Staining; Spatial Behavior; Synapses; Synaptophysin; Time Factors; Valine | 2004 |
Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Benzoxazines; Brain Stem; Calcium Signaling; Cannabinoid Receptor Modulators; Endocannabinoids; Evoked Potentials, Auditory, Brain Stem; Glycine; Ion Transport; Morpholines; Naphthalenes; Nerve Endings; Patch-Clamp Techniques; Picrotoxin; Piperidines; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Resorcinols; Scopolamine; Synaptic Transmission; Xanthenes | 2004 |
Bi-directional plasticity and age-dependent long-term depression at mouse CA3-CA1 hippocampal synapses.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Synapses; Valine | 2004 |
Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Crosses, Genetic; Dentate Gyrus; Disease Models, Animal; Down Syndrome; Evoked Potentials; Female; GABA-A Receptor Antagonists; Gene Dosage; Glycine; Hippocampus; Long-Term Potentiation; Magnesium; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Species Specificity; Trisomy | 2004 |
Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzoates; Brain-Derived Neurotrophic Factor; Cycloleucine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; Neurotrophin 3; Patch-Clamp Techniques; Phosphinic Acids; Rats; Receptors, Metabotropic Glutamate; Spinal Cord; Spinal Nerve Roots | 2005 |
Measurement of presynaptic zinc changes in hippocampal mossy fibers.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoquinolines; Animals; Anticonvulsants; Cholinesterase Inhibitors; Cyclopropanes; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Ethylenediamines; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Mossy Fibers, Hippocampal; Picrotoxin; Rats; Rats, Inbred WF; Synapses; Time Factors; Tosyl Compounds; Zinc | 2004 |
Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Dicarboxylic; Animals; Benzodiazepines; Cyclopropanes; Excitatory Postsynaptic Potentials; Gene Deletion; GluK2 Kainate Receptor; Glycine; Isoquinolines; Isoxazoles; Kainic Acid; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Patch-Clamp Techniques; Potassium; Propionates; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission | 2004 |
Putative NMDA receptors in Hydra: a biochemical and functional study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Cell Membrane; Concanavalin A; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Glutathione; Glycine; Hydra; Kynurenic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2004 |
Local calcium transients regulate the spontaneous motility of dendritic filopodia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Signaling; Cell Movement; Cells, Cultured; Dendrites; Diagnostic Imaging; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Indoles; Pseudopodia; Pyramidal Cells; Pyridazines; Quinoxalines; Rats; Synapses; Time Factors | 2005 |
Distinct roles of glycinergic and GABAergic inhibition in coordinating locomotor-like rhythms in the neonatal mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Motor Activity; N-Methylaspartate; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Picrotoxin; Serotonin; Spinal Cord; Spinal Nerve Roots; Strychnine | 2005 |
Inhibitory synapses in the developing auditory system are glutamatergic.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Transport Systems; Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Auditory Pathways; Bicuculline; Cell Count; Dose-Response Relationship, Radiation; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Immunohistochemistry; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neural Inhibition; Neurons; Olivary Nucleus; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Strychnine; Synapses; Synaptic Transmission; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Proteins; Vesicular Inhibitory Amino Acid Transport Proteins; Vesicular Transport Proteins | 2005 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescence Resonance Energy Transfer; Gene Expression; Glutamic Acid; Glycine; Hippocampus; Humans; Insecta; Luminescent Proteins; Microscopy, Confocal; Molecular Biology; Mutagenesis, Site-Directed; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Quinoxalines; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors; Transfection | 2005 |
Cardiovascular response to a group III mGluR agonist in NTS requires NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Cardiovascular System; Excitatory Amino Acid Agonists; Glycine; Glycine Agents; Male; Microinjections; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Strychnine | 2005 |
Dissection of bidirectional synaptic plasticity into saturable unidirectional processes.
Topics: Animals; Animals, Newborn; Carbazoles; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hippocampus; In Vitro Techniques; Indole Alkaloids; Lissamine Green Dyes; Long-Term Potentiation; Long-Term Synaptic Depression; Models, Biological; Neuronal Plasticity; Okadaic Acid; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Theta Rhythm; Time Factors; Valine | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
Contribution of glutamate receptors to brain-derived neurotrophic factor-induced elevation of intracellular Ca2+levels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain-Derived Neurotrophic Factor; Calcium; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Neurons; Pregnancy; Rats; Receptors, Glutamate; Sodium Channel Blockers; Tetrodotoxin; Visual Cortex | 2005 |
AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Biotinylation; Blotting, Western; Brain; Brefeldin A; Calcium Channel Blockers; Cell Adhesion; Cells, Cultured; Chlorocebus aethiops; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Glycine; In Vitro Techniques; Integrin alphaVbeta3; Mitogen-Activated Protein Kinase Kinases; Neurons; Nifedipine; Paxillin; Phenanthridines; Phosphoproteins; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Quinoxalines; Rats; Receptors, AMPA; src-Family Kinases; Time Factors; Transfection; Valine | 2005 |
Role of group II metabotropic glutamate receptors 2/3 and group I metabotropic glutamate receptor 5 in developing rat medial vestibular nuclei.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Amino Acids; Animals; Animals, Newborn; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Neural Inhibition; Phenylacetates; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Synaptic Transmission; Vestibular Nuclei; Xanthenes | 2005 |
Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Anisomycin; Calcium Channel Blockers; Dentate Gyrus; Dipeptides; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; Glycine; Long-Term Synaptic Depression; Male; Neuroprotective Agents; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors; Verapamil | 2005 |
A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse.
Topics: 2-Amino-5-phosphonovalerate; Adaptor Proteins, Vesicular Transport; Age Factors; Animals; Anticonvulsants; Colforsin; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Huntington Disease; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Nerve Tissue Proteins; Patch-Clamp Techniques; Time Factors | 2005 |
Sustained activation of metabotropic glutamate receptor 5 and protein tyrosine phosphatases mediate the expression of (S)-3,5-dihydroxyphenylglycine-induced long-term depression in the hippocampal CA1 region.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Depression, Chemical; Electrophysiology; Enzyme Activation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Immunoprecipitation; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Neuronal Plasticity; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Synapses | 2006 |
Differential sensitivity of GABAergic and glycinergic inputs to orexin-A in preganglionic cardiac vagal neurons of newborn rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Heart; Intracellular Signaling Peptides and Proteins; Neurons; Neuropeptides; Orexins; Picrotoxin; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vagus Nerve | 2005 |
Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Substitution; Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hippocampus; Humans; Ionomycin; Kidney; Models, Molecular; Mutation, Missense; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Point Mutation; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Isoforms; Protein Processing, Post-Translational; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Synapses; Transfection | 2006 |
Endogenous activation of nicotinic receptors underlies sympathetic tone generation in neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Animals; Animals, Newborn; Autonomic Fibers, Preganglionic; Cholinergic Fibers; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycine; In Vitro Techniques; Interneurons; Kynurenic Acid; Mecamylamine; Nerve Tissue Proteins; Nicotinic Agonists; Nicotinic Antagonists; Organophosphonates; Phenylalanine; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spinal Cord; Splanchnic Nerves; Sympathetic Fibers, Postganglionic; Synaptic Transmission | 2006 |
Coexistence of muscarinic long-term depression with electrically induced long-term potentiation and depression at CA3-CA1 synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Data Interpretation, Statistical; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Muscarinic Agonists; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Synapses | 2006 |
Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Chickens; Cochlear Nucleus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kinetics; Membrane Potentials; Models, Neurological; Neurons; Patch-Clamp Techniques; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission; Xanthenes | 2007 |
Glycine-induced long-term synaptic potentiation is mediated by the glycine transporter GLYT1.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Rats; Rats, Sprague-Dawley; Sarcosine; Strychnine; Synapses | 2007 |
The role of NMDA receptors in regulating group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex.
Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2008 |
NMDA receptor desensitization regulated by direct binding to PDZ1-2 domains of PSD-95.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Cells, Cultured; Disks Large Homolog 4 Protein; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Membrane Proteins; Neurons; Patch-Clamp Techniques; Phorbol Esters; Phosphoproteins; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors; Transfection; Zonula Occludens-1 Protein | 2008 |
Different glutamate receptor mechanisms in long-term depression induced by different stimulus patterns in the CA1 area of adult rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; CA1 Region, Hippocampal; Glycine; Long-Term Synaptic Depression; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2008 |
Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microscopy, Electron, Scanning; N-Methylaspartate; Potassium Chloride; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium; Valine | 2008 |
Impact of protein kinase C activation on epileptiform activity in the hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Benzoates; Benzophenanthridines; Enzyme Activation; Epilepsy; Glutamic Acid; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Picrotoxin; Protein Kinase C; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Signal Transduction | 2008 |
3-Nitropropionic acid depresses spinal reflexes involving GABAergic and glycinergic transmission in neonatal rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Bicuculline; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; Reflex; Spinal Cord; Strychnine; Synaptic Transmission | 2008 |
The contribution of synaptic inputs to sustained depolarizations in reticulospinal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Electric Stimulation; Electromyography; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; In Vitro Techniques; Larva; Lidocaine; Membrane Potentials; Neural Pathways; Neurons; Patch-Clamp Techniques; Petromyzon; Reticular Formation; Spinal Cord; Strychnine; Synapses; Time Factors; Trigeminal Nerve; Valine | 2009 |
Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patterns.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Lidocaine; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Time Factors; Tubulin; Valine | 2009 |
Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Analysis of Variance; Animals; Biophysics; Bromodeoxyuridine; Butadienes; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; GABA Antagonists; Gene Expression Regulation; Glycine; Glycine Agents; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Nitriles; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells | 2009 |
Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats contributes to the induction of persistent LTD via an adenosine-A1 receptor-regulated mechanism.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Biophysics; CA3 Region, Hippocampal; Cyclopropanes; Dihydropyridines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Synaptic Depression; Male; Mossy Fibers, Hippocampal; Rats; Rats, Wistar; Receptor, Adenosine A1; Statistics as Topic; Time Factors; Valine; Wakefulness; Xanthines; Xylenes | 2010 |
Assessment of different induction protocols to elicit long-term depression (LTD) in the rat visual cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Geniculate Bodies; Glycine; Long-Term Synaptic Depression; Male; N-Methylaspartate; Pentobarbital; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Synaptic Potentials; Urethane; Visual Cortex; Visual Pathways | 2010 |
Involvement of inositol-1,4,5-trisphosphate receptors in the bidirectional synaptic plasticity induced in hippocampal CA1 neurons by 1-10 Hz low-frequency stimulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Benzophenanthridines; Boron Compounds; CA1 Region, Hippocampal; Calcium Channel Blockers; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Guinea Pigs; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Neurons; Protein Kinase C; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2010 |
Activation of N-methyl-D-aspartate (NMDA) receptors in the dorsal vagal complex lowers glucose production.
Topics: 2-Amino-5-phosphonovalerate; Animals; Gene Knockdown Techniques; Glucose; Glycine; Humans; Kynurenic Acid; Liver; Male; N-Methylaspartate; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vagotomy; Vagus Nerve | 2010 |
Ventrolateral medulla mechanisms involved in cardiorespiratory responses to central chemoreceptor activation in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Glycine; Hypercapnia; Hypertension; Male; Medulla Oblongata; Models, Neurological; Muscimol; Phrenic Nerve; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Respiratory Physiological Phenomena; Sodium Cyanide; Splanchnic Nerves; Vagotomy | 2011 |
Synapse- and subtype-specific modulation of synaptic transmission by nicotinic acetylcholine receptors in the ventrobasal thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Animals, Newborn; Bicuculline; Cholinesterase Inhibitors; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Galantamine; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Nicotinic Agonists; Patch-Clamp Techniques; Receptors, Nicotinic; Sodium Channel Blockers; Somatosensory Cortex; Synapses; Synaptic Transmission; Tetrodotoxin; Thalamus; Valine | 2011 |
Parasagittally aligned, mGluR1-dependent patches are evoked at long latencies by parallel fiber stimulation in the mouse cerebellar cortex in vivo.
Topics: Animals; Benzoates; Calcium; Cerebellar Cortex; Electric Stimulation; Estrenes; Evoked Potentials; Glycine; Long-Term Potentiation; Male; Mice; Mice, Inbred Strains; Models, Animal; Nerve Fibers; Purkinje Cells; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Ryanodine; Valine | 2011 |
Network oscillations in rod-degenerated mouse retinas.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Age Factors; Animals; Carbenoxolone; Cyclooxygenase Inhibitors; Disease Models, Animal; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glutamic Acid; Glycine; In Vitro Techniques; Light; Male; Meclofenamic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Net; Neural Inhibition; Periodicity; Pyridazines; Quinoxalines; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Sodium Channel Blockers; Statistics as Topic; Tetrodotoxin | 2011 |
Contribution of excitatory amino acid receptors of the retrotrapezoid nucleus to the sympathetic chemoreflex in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Hypercapnia; Male; Phrenic Nerve; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Respiratory Center; Splanchnic Nerves | 2011 |
Suppressive effect of preconditioning low-frequency stimulation on subsequent induction of long-term potentiation by high frequency stimulation in hippocampal CA3 neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; CA3 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Guinea Pigs; Long-Term Potentiation; Mossy Fibers, Hippocampal; Phosphorylation; Synapses; Synaptic Transmission | 2012 |
Glycine exerts dual roles in ischemic injury through distinct mechanisms.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Ischemia; Dose-Response Relationship, Drug; Glucose; Glycine; Hippocampus; Hypoxia, Brain; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Viruses | 2012 |
Triheteromeric N-methyl-D-aspartate receptors differentiate synaptic inputs onto pyramidal neurons in somatosensory cortex: involvement of the GluN3A subunit.
Topics: 2-Amino-5-phosphonovalerate; Algorithms; Animals; Calcium; Electric Stimulation; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; Ion Exchange; Kinetics; Magnesium; Neural Pathways; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synapses | 2012 |
Experience-dependent switch in sign and mechanisms for plasticity in layer 4 of primary visual cortex.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Critical Period, Psychological; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Neuronal Plasticity; Patch-Clamp Techniques; Pyramidal Cells; Rats; Sensory Deprivation; Synaptic Potentials; Time Factors; Valine; Visual Cortex | 2012 |
Membrane insertion of new AMPA receptors and LTP induced by glycine is prevented by blocking NR2A-containing NMDA receptors in the rat visual cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Patch-Clamp Techniques; Phenols; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Visual Cortex | 2013 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
Direct interaction of taurine with the NMDA glutamate receptor subtype via multiple mechanisms.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Dizocilpine Maleate; Glycine; In Vitro Techniques; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Taurine | 2013 |
Astrocytes release D-serine by a large vesicle.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Calcium; Cytoplasmic Vesicles; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Exocytosis; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Microscopy, Electron, Transmission; Patch-Clamp Techniques; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Serine; Valine | 2013 |
Patterned high-frequency stimulation induces a form of long-term depression dependent on GABAA and mACh receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anisomycin; Benzoates; CA1 Region, Hippocampal; Electric Stimulation; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, GABA-A | 2013 |
ALX 1393 inhibits spontaneous network activity by inducing glycinergic tonic currents in the spinal ventral horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Anterior Horn Cells; Biophysical Phenomena; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Net; Organ Culture Techniques; Patch-Clamp Techniques; Serine; Spinal Cord; Time Factors; Valine | 2013 |
Sound localization ability and glycinergic innervation of the superior olivary complex persist after genetic deletion of the medial nucleus of the trapezoid body.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Animals; Animals, Newborn; Auditory Pathways; Early Growth Response Protein 2; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Antagonists; Functional Laterality; Glycine; Glycine Plasma Membrane Transport Proteins; Homeodomain Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Olivary Nucleus; Patch-Clamp Techniques; Sound Localization; Strychnine; Valine | 2013 |
NMDA receptor activation antagonizes the NMDA antagonist-induced antianxiety effect in the elevated plus-maze test in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Male; Maze Learning; Mice; N-Methylaspartate; Quinolones; Receptors, N-Methyl-D-Aspartate; Serine | 2013 |
Electrophysiological characterization of methyleugenol: a novel agonist of GABA(A) receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Eugenol; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; GABA Agents; GABA-A Receptor Agonists; Glutamic Acid; Glycine; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Valine | 2014 |
Synaptic strength at the temporoammonic input to the hippocampal CA1 region in vivo is regulated by NMDA receptors, metabotropic glutamate receptors and voltage-gated calcium channels.
Topics: Animals; CA1 Region, Hippocampal; Calcium Channels, L-Type; Cyclopropanes; Dentate Gyrus; Dose-Response Relationship, Drug; Electric Stimulation; Electrocorticography; Electrodes, Implanted; Excitatory Postsynaptic Potentials; Gallopamil; Glycine; Long-Term Potentiation; Male; Neurotransmitter Agents; Perforant Pathway; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Valine | 2015 |
Impaired bidirectional NMDA receptor dependent synaptic plasticity in the dentate gyrus of adult female Fmr1 heterozygous knockout mice.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Estrous Cycle; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Genotype; Glycine; Hindlimb Suspension; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Spatial Behavior; Swimming; Valine | 2016 |
Differential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks.
Topics: 2-Amino-5-phosphonovalerate; Animals; Efferent Pathways; Glycine; Interneurons; Kynurenic Acid; Mice; Mice, Inbred C57BL; Motor Activity; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinal Nerve Roots; Synapses | 2017 |
The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Learning; Long-Term Potentiation; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Peptide Fragments; Protein Domains; Quinoxalines; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2018 |
Subsaturation of the N-methyl-D-aspartate receptor glycine site allows the regulation of bursting activity in juvenile rat nigral dopamine neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dopaminergic Neurons; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Kynurenic Acid; Pars Compacta; Phosphinic Acids; Propanolamines; Rats; Receptors, N-Methyl-D-Aspartate; Serine | 2019 |