2-amino-5-phosphonovalerate has been researched along with glutamic acid in 648 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (9.57) | 18.7374 |
| 1990's | 320 (49.38) | 18.2507 |
| 2000's | 193 (29.78) | 29.6817 |
| 2010's | 72 (11.11) | 24.3611 |
| 2020's | 1 (0.15) | 2.80 |
| Authors | Studies |
|---|---|
| Bigge, CF; Drummond, JT; Humblet, C; Johnson, G; Malone, TC; Ortwine, DF; Pinter, GW | 1 |
| Anis, NA; Bukownik, R; Eldefrawi, AT; Eldefrawi, ME; Goodnow, RA; Nakanishi, K; Usherwood, PN | 1 |
| Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ | 1 |
| Becker, DP; Hovda, DA; Katayama, Y; Kawamata, T; Yoshino, A | 1 |
| Felipo, V; Grisolía, S; Hermenegildo, C; Marcaida, G; Miñana, MD | 1 |
| Jensen, TS; Yaksh, TL | 1 |
| Aceves, J; Arias-Montaño, JA; Martínez-Fong, D | 1 |
| Hisanaga, K; Sagar, SM; Sharp, FR | 1 |
| Hu, GY; Hvalby, O | 1 |
| Henry, JL; Hong, YG | 1 |
| Gorter, JA; Mirmiran, M; Veerman, M | 1 |
| Beyer, C; Caba, M; Komisaruk, BR; Lòpez-Colomè, AM | 1 |
| Weiland, NG | 1 |
| Moss, RL; Wong, M | 1 |
| Currie, SN; Stein, PS | 1 |
| Flavin, MP; Riopelle, RJ; Yang, Y | 1 |
| Pinnock, RD | 1 |
| Rekling, JC | 1 |
| Sekiguchi, M; Wada, K; Wenthold, RJ | 1 |
| Engelsen, BA; Fonnum, F; Furset, K | 1 |
| Capogna, M; Gähwiler, BH; Scanziani, M; Thompson, SM | 1 |
| Ames, A; Li, YY | 1 |
| Pai, KS; Ravindranath, V | 1 |
| Dunwiddie, TV; Lupica, CR; Proctor, WR | 1 |
| Koob, GF; Maldonado-Lopez, R; Pulvirenti, L | 1 |
| Wayman, CP; Wilson, JF | 1 |
| Holopainen, I; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Marini, AM; Paul, SM; Weller, M | 1 |
| Kuno, M; Matsuura, S; Nakamura, F | 1 |
| Evans, PD; Merzon, RM; Reale, V; Villegas, J | 2 |
| Ivanova, SF; Sanzharovskiĭ, AV; Storozhuk, VM | 1 |
| Bagetta, G; Bowery, NG; Britton, P; Nisticó, G; Whitton, P | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Calo, G; Tomasini, C; Vedovato, M | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Hestrin, S | 1 |
| Horii, A; Mochizuki, T; Okakura, K; Wada, H; Yamatodani, A | 1 |
| Bonhaus, DW; McNamara, JO | 1 |
| Chiorri, C; Cordi, AA; Dappen, MS; Monahan, JB; Natalini, B; Pellicciari, R | 1 |
| Crane, AM; Driscoll, BF; Law, MJ | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Frenguelli, BG | 1 |
| Kihara, M; Kubo, T; Misu, Y | 1 |
| Frye, GD | 1 |
| Angst, C; Brundish, DE; Fagg, G; Hurt, SD; Pozza, M; Sills, MA; Williams, M; Wilusz, EJ | 1 |
| Rosenberg, PA | 1 |
| Higashi, H; Nishi, S; Tanaka, E | 1 |
| Dougherty, PM; Willis, WD | 1 |
| Kuramoto, K; Nishimura, S; Sorimachi, M | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Davidoff, RA; Hackman, JC | 1 |
| Monaghan, DT | 1 |
| Dreyer, EB; Kaiser, PK; Lipton, SA; Sucher, NJ | 1 |
| Sapru, H; Sundaram, K | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Beilin, B; Cohn, S; Ginzburg, R; Seltzer, Z | 1 |
| Chetkovich, DM; Gray, R; Johnston, D; Sweatt, JD | 1 |
| North, RA; Uchimura, N | 1 |
| Higashi, H; Inokuchi, H; Nishi, S; Nose, I | 1 |
| Canton, H; Colpaert, F; Lehmann, J | 1 |
| Cline, HT; Constantine-Paton, M; Debski, EA; McDonald, JW | 1 |
| Eysel, UT; FitzGibbon, T; Funke, K | 1 |
| Isokawa, M; Mello, LE | 1 |
| Delrée, P; Lefebvre, PP; Leprince, P; Moonen, G; Rigo, JM; Rogister, B; Weber, T | 1 |
| Schmidt, M | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ | 1 |
| Oja, SS; Saransaari, P | 1 |
| Jean, A; Kessler, JP | 1 |
| Cherubini, E; Kilić, G; Moran, O | 1 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Fukushima, R; Kizu, A; Miyagishi, T; Ono, T; Yoshida, Y | 1 |
| Frusciante, MJ; Javitt, DC; Nussenzveig, IZ; Sircar, R; Wong, ML; Zukin, SR | 1 |
| Sarafian, T; Torres, M; Verity, MA | 1 |
| Coulter, DA; DeLorenzo, RJ; Sombati, S | 1 |
| Billard, JM; Daniel, H; Pumain, R | 1 |
| Cuénod, M; Do, KQ; Fontana, A; Frei, K; Piani, D | 1 |
| Koob, GF; Pulvirenti, L; Swerdlow, NR | 1 |
| Fink, K; Göthert, M | 1 |
| McMillian, M; Miller, LG; Schatzki, A | 1 |
| Cline, HT; Tsien, RW | 1 |
| Benveniste, M; Mayer, ML | 1 |
| Bading, H; Greenberg, ME | 1 |
| Weiss, S | 1 |
| Bradford, HF; Croucher, MJ | 1 |
| Markram, H; Segal, M | 1 |
| Clements, JD; Jahr, CE; Lester, RA; Westbrook, GL | 1 |
| Miyamoto, T; Okada, Y; Sakurai, T | 1 |
| Adams, RN; Bunney, BS; Gruen, RJ; Moghaddam, B; Roth, RH | 1 |
| Becquet, D; Faudon, M; Hery, F | 1 |
| Beal, MF; DiFiglia, M; Freese, A; Koroshetz, WJ; Martin, JB | 1 |
| Blanton, MG; Kriegstein, AR; Lo Turco, JJ | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Cordi, AA; Monahan, JB; Reisse, J | 1 |
| Khaspekov, LG; Lisý, V; Stastný, F; Viktorov, IV | 1 |
| Ehrenberger, K; Felix, D | 1 |
| Jean, A; Tell, F | 1 |
| Gobert, A; Guibert, B; Leviel, V | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Cherubini, E; King, AE; Nistri, A | 1 |
| Clow, DW; Jhamandas, K | 1 |
| Barbeito, L; Cheramy, A; Girault, JA; Glowinski, J; Godeheu, G; Pittaluga, A | 1 |
| Hoehn, K; White, TD | 1 |
| Ogita, K; Yoneda, Y | 1 |
| Bode-Greuel, KM; Singer, W | 1 |
| Hauber, W; Schmidt, WJ | 1 |
| Choi, DW; Hartley, DM | 1 |
| Caspary, DM; Faingold, CL; Hoffmann, WE | 1 |
| Cox, JA; Henneberry, RC; Lysko, PG; Vigano, MA | 1 |
| Itzhak, Y | 1 |
| Dye, J; Heiligenberg, W; Kawasaki, M; Keller, CH | 1 |
| Hestrin, S; Nicoll, RA; Sah, P | 1 |
| Laguzzi, R; Le Galloudec, E; Merahi, N | 1 |
| Gallagher, JP; Hasuo, H | 2 |
| King, AE; Nistri, A; Rovira, C | 1 |
| Hablitz, JJ | 1 |
| Henneberry, RC; Novelli, A | 1 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| Jahr, CE; Yoshioka, K | 1 |
| Nelson, PG; Pun, RY; Westbrook, GL | 1 |
| Beart, PM; Manallack, DT | 1 |
| Freeman, JA; Langdon, RB | 1 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Gordon, FJ | 1 |
| Fagg, GE; Foster, AC | 1 |
| Bliss, TV; Errington, ML; Lynch, MA | 1 |
| Jhamandas, K; Marien, M | 1 |
| Ito, K; Izumi, Y; Kato, H; Kudo, Y; Miyakawa, H; Ogura, A | 1 |
| Foster, AC; Wong, EH | 1 |
| Crepel, F; Dupont, JL; Gardette, R | 1 |
| Javitt, DC; Jotkowitz, A; Sircar, R; Zukin, SR | 1 |
| Crunelli, V; Kelly, JS; Leresche, N; Pirchio, M | 1 |
| Samanin, R; Vezzani, A; Wu, HQ | 1 |
| Choi, DW; Peters, S | 1 |
| Choi, DW; Goldberg, MP; Pham, PC; Weiss, JH | 1 |
| Choi, DW; Koh, JY; Peters, S | 1 |
| Hagiwara, S; Hirano, T | 1 |
| Kloog, Y; Nadler, V; Sokolovsky, M | 1 |
| Krishtal, OA; Smirnov, SV | 1 |
| Shinozaki, H | 1 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Ambar, I; Kloog, Y; Sokolovsky, M | 1 |
| Kihara, M; Kubo, T | 1 |
| Connick, JH; Stone, TW | 1 |
| Jones, AW; Olverman, HJ; Watkins, JC | 1 |
| King, AE; Thompson, SW; Urban, L; Woolf, CJ | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Raigorodsky, G; Urca, G | 1 |
| Kapetanovic, IM; Kupferberg, HJ; Torchin, CD; Yonekawa, WD | 1 |
| Lovinger, DM; Weight, FF | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 1 |
| Ikeda, H; Sheardown, MJ | 1 |
| Curtis, DR; Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Leah, JD; Peet, MJ | 1 |
| Lehmann, J; Scatton, B | 1 |
| Davies, J; Watkins, JC | 1 |
| Coyle, JT; Ferkany, JW | 1 |
| Mayer, ML; Westbrook, GL | 1 |
| Halsey, MJ; Meldrum, BS; Wardley-Smith, B | 1 |
| King, AE; Wheal, HV | 1 |
| Buchhalter, JR; Djali, S; Robinson, MB | 1 |
| Backus, KH; Trube, G | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R; Tribillac, F | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Mikuni, M; Saitoh, K; Shinno, H; Takahashi, K; Tomita, U; Yamawaki, S | 1 |
| Glowinski, J; Jay, TM; Pirot, S; Thierry, AM | 1 |
| Laurie, DJ; Seeburg, PH | 1 |
| Kasparov, S; Pawelzik, H; Zieglgänsberger, W | 1 |
| Baba, A; Goji, K; Kawai, N; Klenerová, V; Moroji, T; Sagi, N; Takamori, E; Yamamoto, H; Yamamoto, T | 1 |
| Devillers, JP; Simonnet, G | 1 |
| Dowling, JE; Grant, GB | 1 |
| Coco, S; Fumagalli, G; Matteoli, M; Verderio, C | 1 |
| Chung, SH; Premkumar, L | 1 |
| Abdel-Rahman, AA; Mao, L | 1 |
| Fitzakerley, JL; McGee, J; Walsh, EJ | 2 |
| Hardy, M; Lee, VM; Pleasure, D; Pleasure, SJ; Reddy, UR; Shi, QY; Tang, CM; Younkin, DP | 1 |
| Jaarsma, D; Korf, J; Sebens, JB | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Kimura, H; Schubert, D | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Greer, RA; Hall, ME; Stewart, JM | 1 |
| Reis, DJ; Sun, MK | 1 |
| Mennini, T; Miari, A; Presti, ML; Rizzi, M; Samanin, R; Vezzani, A | 1 |
| Chao, CC; Hu, S | 1 |
| Bading, H; Dudek, H; Greenberg, ME; Lipton, SA; Segal, MM; Sucher, NJ | 1 |
| Allen, CN; Jiang, ZG; North, RA | 1 |
| Mennerick, S; Zorumski, CF | 1 |
| Cosentino, M; De Ponti, F; Frigo, G; Giaroni, C; Lecchini, S; Leoni, O; Marino, F | 1 |
| Driscoll, BF; Law, MJ; Sokoloff, L; Takahashi, S | 1 |
| Croucher, MJ; Patel, DR; Sturt, NJ | 1 |
| Bigge, CF; Borosky, SA; Li, JH; Ortwine, DF; Vartanian, MG; Williamson, RM | 1 |
| Dudley, CA; Moss, RL | 1 |
| Kagawa, M; Kuraishi, Y; Minami, M; Onogi, T; Satoh, M | 1 |
| Kelley, AE; Maldonado-Irizarry, CS | 1 |
| Bolinao, ML; Moghaddam, B | 1 |
| Harris, C; Liu, D; Sturman, J; Trenkner, E | 1 |
| Bloc, A; Dusticier, N; Forni, C; Kerkerian-Le Goff, L; Samuel, D | 1 |
| Daszuta, A; Forni, C; Moukhles, H; Nieoullon, A | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M | 1 |
| Han, D; Ogita, K; Suzuki, T; Yoneda, Y; Zuo, P | 1 |
| D'Hooge, R; De Deyn, PP; Pei, YQ | 1 |
| Hyvönen, M; Lahtinen, H; Miettinen, R; Riekkinen, PJ; Sirviö, J; Ylinen, A | 1 |
| López-Colomé, AM; Ortega, A; Romo-de-Vivar, M | 1 |
| Allgeier, H; Angst, C; Baud, J; Gunzenhauser, W; Heckendorn, R | 1 |
| Taube, JS | 1 |
| Durand, J | 1 |
| Sluka, KA; Westlund, KN | 2 |
| Paul, SM; Weller, M | 1 |
| Cavalié, A; García, DE; Lux, HD | 1 |
| Starr, BS; Starr, MS | 1 |
| Mori, N | 1 |
| Jonas, P; Major, G; Sakmann, B | 1 |
| Ferko, AP | 1 |
| Giaume, C; Peusner, KD | 1 |
| Floridi, S; Racagni, G; Tromba, C; Trotti, D; Volterra, A | 1 |
| Puro, DG; Uchihori, Y | 1 |
| Cabrera, RJ; Donoso, AO; Navarro, CE | 1 |
| Dailey, ME; Smith, SJ | 1 |
| Hyson, RL; Nathanson, NM; Rubel, EW; Zirpel, L | 1 |
| Greenberger, V; Khodorov, BI; Pinelis, VG; Segal, M | 1 |
| Bousquet, P; Feldman, J; Mettauer, B; Monassier, L; Roegel, JC; Tibiriça, E | 1 |
| Beck, SG; Dun, NJ; Read, HL | 1 |
| Aizenman, E; Blitzblau, RC; Hartnett, KA; Rosenberg, PA; Speliotes, EK | 1 |
| Biggio, G; Foddi, MC; Ghiani, CA; Motzo, C; Serra, M | 1 |
| Liu, H; Xu, M | 1 |
| Ehmann, S; Singh, SP; Snyder, AK | 1 |
| Manabe, T; Manzoni, OJ; Nicoll, RA | 1 |
| Boulu, RG; Callebert, J; Ghribi, O; Plotkine, M | 1 |
| Glowinski, J; Marin, P; Premont, J; Tassin, JP; Trovero, F | 1 |
| Kataoka, Y; Ohmori, H | 2 |
| Kataoka, Y; Koizumi, S; Niwa, M; Taniyama, K; Watanabe, S | 1 |
| Donoghue, JP; Hess, G; Jacobs, KM | 1 |
| Hablitz, JJ; Pelletier, MR | 1 |
| Onozuka, M; Watanabe, K | 1 |
| Amalric, M; Baunez, C; Nieoullon, A; Ouagazzal, A | 1 |
| Dai, X; Douglas, JR; Jordan, LM; Noga, BR | 1 |
| Blessing, WW; Gieroba, ZJ | 1 |
| Ebner, TJ; Elias, SA; Yae, H | 1 |
| Koch, M; Krase, W; Schnitzler, HU | 1 |
| Kaila, K; Smirnov, S; Taira, T; Voipio, J | 1 |
| Boje, KM; Skolnick, P; Wong, G | 1 |
| Komuro, H; Rakic, P | 1 |
| Bouskila, Y; Dudek, FE | 1 |
| Peng, L; Zhao, Z | 1 |
| Bazil, MK; Gordon, FJ | 1 |
| Han, D; Ogita, K; Yoneda, Y; Zuo, P | 1 |
| Trombley, PQ; van den Pol, AN | 1 |
| Belhage, B; Hansen, GH; Schousboe, A | 1 |
| Feuerstein, G; Jiang, ZG; Yue, TL | 1 |
| Buchwald, NA; Cohen, RW; Levine, MS; Radisavljevic, Z; Siviy, SM; Walsh, JP | 1 |
| Köller, H; Müller, HW; Siebler, M | 1 |
| Berger, TW; Grace, AA; Nisenbaum, ES | 1 |
| Orrego, F; Riquelme, G; Villanueva, S; Wyneken, U | 1 |
| Morishita, W; Sastry, BR; Shew, TR | 1 |
| Golding, NL; Oertel, D | 1 |
| Lu, L; Mcgonigle, P; Munir, M | 1 |
| Akhondzadeh, S; Stone, TW | 1 |
| Armstrong, JD; Barb, CR; Campbell, RM; Cox, NM | 1 |
| Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
| Dudel, J; Parnas, H; Parnas, I; Ravin, R | 1 |
| Huganir, RL; Moshaver, A; Raymond, LA; Tingley, WG | 1 |
| Dee, MG; Donias, HW; Duva, MA; Stanley, BG; Willett, VL | 1 |
| Cynader, MS; Wang, Y; Yang, B | 1 |
| Matsuki, N; Saito, H; Tanaka, T | 1 |
| Aistrup, GL; Babcock, KK; Kumar, KN; Michaelis, EK; Schowen, RL; Szentirmay, M | 1 |
| Feltz, P; Jo, YH; Poisbeau, P; Schlichter, R | 1 |
| Magsumov, ST; Nikolsky, EE; Poletayev, GI; Urazaev, AK; Vyskocil, F | 1 |
| Albers, HE; Bamshad, M; Cooper, TT; Karom, M | 1 |
| Fleischer-Lambropoulos, E; Geladopoulos, T; Kazazoglou, T; Kentroti, S; Stefanis, C; Vernadakis, A | 1 |
| Belousov, A; Obrietan, K; Van Den Pol, AN | 1 |
| Laurie, D; Lowe, DA; Meier, CL; Müller, W; Urwyler, S | 1 |
| Chao, CC; Ehrlich, L; Hu, S; Peterson, PK | 1 |
| Ferreira, SH; Lorenzetti, BB | 1 |
| el Idrissi, A; Harris, C; Trenkner, E | 1 |
| Graham, SH; Simon, RP; Tanaka, K | 1 |
| Berretta, N; Jones, RS | 1 |
| Alici, K; Gloveli, T; Heinemann, U; Motine, V; Weber-Luxenburger, G | 1 |
| Attwell, D; Sarantis, M; Takahashi, M | 1 |
| Glitsch, M; Llano, I; Marty, A | 1 |
| Crill, W; Schwindt, P | 1 |
| Ding, JM; Faiman, LE; Gillette, MU; Hurst, WJ; Kuriashkina, LR | 1 |
| Craenen, G; Grants, I; Jeftinija, S; Lucas, JH | 1 |
| Chai, CY; Chen, SY; Kuo, JS; Tseng, CJ; Wu, WC | 1 |
| Haberecht, MF; Lo, GJ; Mitchell, CK; Redburn, DA | 1 |
| Ciani, E; Contestabile, A; Paulsen, RE; Rizzi, S | 1 |
| Betz, H; Hirai, H; Kuhse, J; Laube, B; Sturgess, M | 1 |
| Belousov, AB; van den Pol, AN | 2 |
| Casula, A; Diana, M; Gessa, GL; Lilliu, V; Mereu, G; Musa, A; Vargiu, PF | 1 |
| Fergus, A; Lee, KS | 1 |
| Bonagamba, LG; Colombari, E; Machado, BH | 1 |
| Fujikawa, DG | 1 |
| Furukawa, K; Holtsberg, FW; Keller, JN; Mattson, MP; Steiner, MR; Steiner, SM | 1 |
| Janáky, R; Jenei, Z; Oja, SS; Saransaari, P; Varga, V | 1 |
| Dorandeu, F; Fosbraey, P; Lallement, G; Pernot-Marino, I; Tattersall, JE; Wetherell, J | 1 |
| Bock, J; Braun, K; Schnabel, R | 1 |
| Frandsen, A; Hansen, HS; Lauritzen, L; Schousboe, A; Strand, AM; Vinggaard, AM | 1 |
| Cui, LN; Dyball, RE; Saeb-Parsy, K | 1 |
| Blasi, F; Guerrini, L; Kistler, B; Molteni, A; Wirth, T | 1 |
| Cohen, SM; Nadler, JV | 1 |
| Barbour, B; Clark, BA | 1 |
| Gwag, BJ; Robine, V; Sessler, FM; Springer, JE | 1 |
| Amano, M; Asari, T; Fukumori, R; Hagiwara, Y; Kubo, T | 1 |
| Fukumori, R; Kubo, T; Yamaguchi, H; Yanagihara, Y | 1 |
| Augustine, GJ; Gee, KR; Pettit, DL; Wang, SS | 1 |
| Abercrombie, ED; DeBoer, P | 1 |
| Richardson, CM; Wakerley, JB | 1 |
| Grünschlag, CR; Haas, HL; Stevens, DR | 1 |
| Ciani, E; Contestabile, A; Dall'Olio, R; Gandolfi, O; Sparapani, M | 1 |
| Bristow, DR; Wood, AM | 1 |
| Hatanaka, H; Numakawa, T; Ogura, A; Sakai, N; Yamada, M | 1 |
| Chen, G; Gao, XB; van den Pol, AN | 1 |
| Iadecola, C; Yang, G | 1 |
| Cronin, AS; Ebling, FJ | 1 |
| Chai, CY; Kuo, JS; Wang, Y; Wu, WC | 1 |
| Desai, NS; Leslie, KR; Nelson, SB; Rutherford, LC; Turrigiano, GG | 1 |
| Aroniadou-Anderjaska, V; Ennis, M; Keller, A; Sheppard, NF; Shipley, MT; Yagodin, S; Zimmer, LA | 1 |
| Emson, PC; Hathway, GJ; Humphrey, PP; Kendrick, KM | 1 |
| Cragg, SJ; Greenfield, SA; Hawkey, CR; Holmes, C | 1 |
| Dunworth, SJ; Stephens, DN | 1 |
| Mason, CA; Morrison, ME | 1 |
| Constantine-Paton, M; Lin, SY | 1 |
| Barnstable, CJ; Otori, Y; Wei, JY | 1 |
| Crill, WE; Schwindt, PC | 1 |
| Boettiger, CA; Doupe, AJ | 1 |
| Almeida, A; Bolaños, JP; Heales, SJ; Medina, JM | 1 |
| Blond, O; Crépel, F; Desce, JM; Otani, S | 1 |
| Becker, A; Hoellt, V; Schroeder, H | 1 |
| Black, JA; Robert, A; Waxman, SG | 1 |
| Fowler, CJ; Hedin, H; Jacobsson, SO; Sellström, A | 1 |
| Kötter, R; Luhmann, HJ; Staiger, JF; Zilles, K | 2 |
| Günel, MA; Kara, I; Koyuncuoğlu, H; Nurten, A; Yamantürk, P | 1 |
| Grigortsevich, N; Khodorov, B; Pinelis, V; Sorokina, E; Storozhevykh, T; Vergun, O; Vinskaya, N | 1 |
| Aou, S; Hori, T; Kamikawa, H; Nakane, H; Tashiro, N | 1 |
| Belousov, AB; Heller, HC; Obrietan, K; van den Pol, AN; Yang, Y | 1 |
| Cairns, BE; Hu, JW; Sessle, BJ | 1 |
| Moghaddam, B; Takahata, R | 1 |
| Magistretti, PJ; Martin, JL; Pellegri, G | 1 |
| Cassidy, RM; Gale, K | 1 |
| Dong, L; Durham, HD; Figlewicz, DA; Minotti, S; Roy, J | 1 |
| Endo, K; Hori, Y; Kitajima, T; Ogata, H; Yamaguchi, S | 1 |
| Boulu, RG; Callebert, J; Lancelot, E; Plotkine, M; Revaud, ML | 1 |
| Castro, E; Krishtal, O; Miras-Portugal, MT; Pankratov, Y | 1 |
| Matsuoka, T; Nishizaki, T; Nomura, T; Tsujishita, Y | 1 |
| Nicoll, RA; Vogt, KE | 1 |
| Hay, M; Lindsley, KA | 1 |
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| Alaei, H; Eidi, A; Keramatian, A; Radahmadi, M | 1 |
| Aubrey, KR; Balle, T; Otsu, Y; Sheipouri, D; Vandenberg, RJ | 1 |
4 review(s) available for 2-amino-5-phosphonovalerate and glutamic acid
| Article | Year |
|---|---|
On the excitatory post-synaptic potential evoked by stimulation of the optic tract in the rat lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aminobutyrates; Animals; Aspartic Acid; Calcium; Dipeptides; Glutamates; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Optic Nerve; Rats; Rats, Inbred Strains; Synapses; Thalamic Nuclei; Valine | 1987 |
Pharmacology of the glutamate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Antidepressive Agents; Azepines; Glutamates; Glutamic Acid; Membrane Potentials; Nervous System Diseases; Neurons; Oxazoles; Oxazolidinones; Piperidines; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1988 |
Roles of excitatory amino acids in expression of secondarily generalized limbic seizures: observations in the kindling model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dimethyl Sulfoxide; Electric Stimulation; Glutamates; Glutamic Acid; Humans; Kindling, Neurologic; Seizures | 1993 |
Modulation of allopregnanolone on excitatory transmitters release from single glutamatergic terminal.
Topics: Animals; Animals, Newborn; Bicuculline; Biophysics; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutamic Acid; Muscimol; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnanolone; Presynaptic Terminals; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Tetraethylammonium; Valine | 2013 |
1 trial(s) available for 2-amino-5-phosphonovalerate and glutamic acid
| Article | Year |
|---|---|
Aspartate and glutamate modulation of growth hormone secretion in the pig: possible site of action.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Aspartic Acid; Body Weight; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; N-Methylaspartate; Ovariectomy; Pituitary Gland, Anterior; Serum Albumin; Swine | 1996 |
643 other study(ies) available for 2-amino-5-phosphonovalerate and glutamic acid
| Article | Year |
|---|---|
Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists.
Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1992 |
Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Iodine Radioisotopes; Kinetics; Male; Neurotoxins; Polyamines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Spermine; Synaptic Membranes; Wasp Venoms | 1991 |
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes | 1990 |
Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Brain Concussion; Dialysis; Energy Metabolism; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ions; Kynurenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors.
Topics: Ammonia; Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1992 |
The antinociceptive activity of excitatory amino acids in the rat brainstem: an anatomical and pharmacological analysis.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Mapping; Brain Stem; Diencephalon; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Medulla Oblongata; Mesencephalon; Microinjections; N-Methylaspartate; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Reticular Formation; Stereotaxic Techniques | 1992 |
Glutamate stimulation of tyrosine hydroxylase is mediated by NMDA receptors in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Kynurenic Acid; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tyrosine 3-Monooxygenase | 1992 |
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Proto-Oncogene Proteins c-fos; Signal Transduction | 1992 |
Glutamate-induced action potentials are preceded by regenerative prepotentials in rat hippocampal pyramidal cells in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; Microelectrodes; Neurons; Pyramidal Tracts; Rats; Rats, Inbred WKY; Tetrodotoxin | 1992 |
Glutamate, NMDA and NMDA receptor antagonists: cardiovascular effects of intrathecal administration in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1992 |
Hippocampal neuronal responsiveness to NMDA agonists and antagonists in the adult rat neonatally treated with MK-801.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Hippocampus; Iontophoresis; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Administration of AP5, a glutamate antagonist, unmasks glycine analgesic actions in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Electroshock; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Injections, Spinal; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Vocalization, Animal | 1992 |
Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding Sites; Binding, Competitive; Estradiol; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Ovariectomy; Progesterone; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Electrophysiology; Estradiol; Female; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Time Factors | 1992 |
Glutamate antagonists applied to midbody spinal cord segments reduce the excitability of the fictive rostral scratch reflex in the turtle.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Thorax; Turtles | 1992 |
The effect of hypoxia on neurotransmitter phenotype of forebrain cholinergic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cell Hypoxia; Cells, Cultured; Choline O-Acetyltransferase; Embryo, Mammalian; Glutamates; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Growth Factors; Neurons; Phenotype; Prosencephalon; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Interaction between thyrotropin-releasing hormone (TRH) and NMDA-receptor-mediated responses in hypoglossal motoneurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Brain Stem; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Synapses; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1992 |
N-acetylaspartylglutamate acts as an agonist upon homomeric NMDA receptor (NMDAR1) expressed in Xenopus oocytes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cloning, Molecular; Dipeptides; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Oocytes; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Transcription, Genetic; Xenopus laevis | 1992 |
Changes in the levels of glutamate and related amino acids in the intact and decorticated rat neostriatum during various conditions associated with convulsions.
Topics: 2-Amino-5-phosphonovalerate; Acetates; Amino Acids; Animals; Anticonvulsants; Brain Mapping; Caudate Nucleus; Cerebral Cortex; Cerebral Decortication; Corpus Striatum; Electroencephalography; Epilepsy, Tonic-Clonic; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutaminase; Hypoglycemia; Insulin; Male; Methionine Sulfoximine; Penicillin G; Putamen; Rats; Rats, Wistar; Seizures; Synaptic Transmission | 1992 |
Presynaptic inhibition of miniature excitatory synaptic currents by baclofen and adenosine in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine; Animals; Baclofen; Bicuculline; Cadmium; Calcium; Electric Conductivity; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamates; Glutamic Acid; Hippocampus; Quinoxalines; Rats; Receptors, GABA-A; Synapses; Tetrodotoxin | 1992 |
Energy requirements of glutamatergic pathways in rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Energy Metabolism; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kainic Acid; Light; Oxygen Consumption; Quinoxalines; Rabbits; Retina | 1992 |
Quisqualic acid-induced neurotoxicity is protected by NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ion Channel Gating; L-Lactate Dehydrogenase; Mice; Potassium; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1992 |
Dissociation of mu and delta opioid receptor-mediated reductions in evoked and spontaneous synaptic inhibition in the rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Axons; Baclofen; Bicuculline; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses | 1992 |
NMDA receptors in the nucleus accumbens modulate intravenous cocaine but not heroin self-administration in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Dopamine; Glutamates; Glutamic Acid; Heroin; Male; Microinjections; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration | 1992 |
Endogenous glutamate stimulates release of alpha-melanocyte-stimulating hormone from the rat hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; alpha-MSH; Animals; Glutamates; Glutamic Acid; Hypothalamus; In Vitro Techniques; Kainic Acid; Male; Neurons; Osmolar Concentration; Pro-Opiomelanocortin; Rats; Rats, Wistar | 1992 |
Effect of magnesium on calcium influx activated by glutamate and its agonists in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Nifedipine; Phencyclidine; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Verapamil | 1992 |
Niacinamide blocks 3-acetylpyridine toxicity of cerebellar granule cells in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Mazindol; N-Methylaspartate; Neurons; Niacinamide; Pyridines; Rats; Rats, Sprague-Dawley; Selegiline; Tetrahydrofolates | 1992 |
Glutamate-induced inhibition of paired pulse facilitation of monosynaptic excitatory post-synaptic potentials in frog spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Magnesium; Membrane Potentials; Motor Neurons; Quinoxalines; Rana catesbeiana; Spinal Cord | 1992 |
N-methyl-D-aspartate (NMDA) and non-NMDA (metabotropic) type glutamate receptors modulate the membrane potential of the Schwann cell of the squid giant nerve fibre.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Axons; Decapodiformes; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schwann Cells | 1992 |
The effect of a glutamate uptake inhibitor on axon-Schwann cell signalling in the squid giant nerve fibre.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Axons; Decapodiformes; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Membrane Potentials; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schwann Cells | 1992 |
[Role of glutamate intracortical connections in conditioned reflex activity].
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Cerebral Cortex; Conditioning, Classical; Evoked Potentials, Somatosensory; Glutamates; Glutamic Acid; Iontophoresis; Ketamine; Kynurenic Acid; Membrane Potentials; Neurons; Receptors, N-Methyl-D-Aspartate | 1992 |
Intrahippocampal tetanus toxin produces generalized convulsions and neurodegeneration in rats: antagonism by NMDA receptor blockers.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dizocilpine Maleate; Epilepsy, Generalized; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Nerve Degeneration; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetanus Toxin | 1992 |
A simple method for electrical field stimulation of cultured granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Temperature; Tetrodotoxin; Veratridine | 1992 |
Presynaptic modulation of amino acid release from synaptosomes.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Male; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptosomes | 1992 |
Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Magnesium; Membrane Potentials; Neurons; Picrotoxin; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Time Factors | 1992 |
Glutamatergic regulation of histamine release from rat hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glutamates; Glutamic Acid; Histamine Release; Hypothalamus, Anterior; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1992 |
Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Culture Techniques; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Synthesis and biological evaluation of cyclopropyl analogues of 2-amino-5-phosphonopentanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Indicators and Reagents; Kainic Acid; Kinetics; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes; Tritium | 1991 |
Cell damage associated with changing the medium of mesencephalic cultures in serum-free medium is mediated via N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Buffers; Cells, Cultured; Culture Media; Dizocilpine Maleate; Glutamates; Glutamic Acid; Mesencephalon; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1991 |
Electrogenic uptake contributes a major component of the depolarizing action of L-glutamate in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport, Active; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; In Vitro Techniques; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Synaptic Transmission | 1991 |
Ipsilateral but not contralateral blockade of excitatory amino acid receptors in the caudal ventrolateral medulla inhibits aortic baroreceptor reflex in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aorta; Blood Pressure; Dizocilpine Maleate; Electric Stimulation; Glutamates; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Muscimol; N-Methylaspartate; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Reflex; Synaptic Transmission | 1991 |
Interaction of ethanol and L-glutamate in the guinea pig ileum myenteric plexus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Electric Stimulation; Ethanol; Female; Glutamates; Glutamic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Magnesium; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serotonin; Tetrodotoxin | 1991 |
[3H]CGP 39653: a new N-methyl-D-aspartate antagonist radioligand with low nanomolar affinity in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cerebral Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glutamates; Glutamic Acid; Glutamine; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Synaptic responses of guinea pig cingulate cortical neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Guinea Pigs; Gyrus Cinguli; Magnesium; Neurons; Quinoxalines; Synapses | 1991 |
Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Glutamates; Glutamic Acid; Macaca fascicularis; N-Methylaspartate; Neurons; Quisqualic Acid; Spinothalamic Tracts | 1991 |
Receptor types mediating the rise in the cytosolic free calcium concentration by L-aspartate and L-glutamate in immature cerebellar neurons with N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cerebellum; Cytosol; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kinetics; Magnesium; Neurons; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
Dorsal root potentials in the isolated frog spinal cord: amino acid neurotransmitters and magnesium ions.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kynurenic Acid; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Potassium Channels; Quinoxalines; Rana pipiens; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Nerve Roots; Synaptic Transmission | 1991 |
Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors.
Topics: Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Glutamates; Glutamic Acid; In Vitro Techniques; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Thalamus; Valine | 1991 |
Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; Alanine Transaminase; Animals; Calcium; Dizocilpine Maleate; Glutamates; Glutamic Acid; HIV Envelope Protein gp120; N-Methylaspartate; Neurotoxins; Osmolar Concentration; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Modulation of neuropathic pain behavior in rats by spinal disinhibition and NMDA receptor blockade of injury discharge.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dizocilpine Maleate; Electric Stimulation; Glutamates; Glutamic Acid; Glycine; Injections, Spinal; Male; Pain; Peripheral Nerve Injuries; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine | 1991 |
N-methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channels; Cyclic AMP; Egtazic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Baclofen and adenosine inhibit synaptic potentials mediated by gamma-aminobutyric acid and glutamate release in rat nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Nucleus Accumbens; Phenylisopropyladenosine; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Purinergic; Synapses | 1991 |
Synaptic responses of guinea pig and rat central amygdala neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine; Amino Acids; Amygdala; Animals; Baclofen; Electric Stimulation; Electrodes; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Male; Neuromuscular Depolarizing Agents; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Synapses | 1991 |
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Biguanides; Binding, Competitive; Biogenic Polyamines; Biotransformation; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Chronic application of NMDA decreases the NMDA sensitivity of the evoked tectal potential in the frog.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; N-Methylaspartate; Optic Nerve; Quisqualic Acid; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1991 |
Retinogeniculate transmission by NMDA and non-NMDA receptors in the cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Geniculate Bodies; Glutamates; Glutamic Acid; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Synaptic Transmission | 1991 |
NMDA receptor-mediated excitability in dendritically deformed dentate granule cells in pilocarpine-treated rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1991 |
Kainate and NMDA toxicity for cultured developing and adult rat spiral ganglion neurons: further evidence for a glutamatergic excitatory neurotransmission at the inner hair cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cell Survival; Cells, Cultured; Cochlea; Ganglia; Glutamates; Glutamic Acid; Hair Cells, Auditory, Inner; Immunohistochemistry; In Vitro Techniques; Indicators and Reagents; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Organ of Corti; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Transmission | 1991 |
Mediation of visual responses in the nucleus of the optic tract in cats and rats by excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Evoked Potentials; Evoked Potentials, Visual; Female; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Optic Chiasm; Photic Stimulation; Quinoxalines; Quisqualic Acid; Rats; Receptors, Neurotransmitter | 1991 |
Excitatory transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Amygdala; Animals; Cerebrospinal Fluid; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Male; Membrane Potentials; Neurons, Afferent; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Receptor sub-types involved in responses of Purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Animals; Aspartic Acid; Bicuculline; Cerebellum; Electric Stimulation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Excitatory amino acids evoke taurine release from cerebral cortex slices from adult and developing mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dipeptides; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotoxins; Potassium; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Secretory Rate; Stimulation, Chemical; Taurine | 1991 |
Evidence that activation of N-methyl-D-aspartate (NMDA) and non-NMDA receptors within the nucleus tractus solitarii triggers swallowing.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Decerebrate State; Deglutition; Facial Nerve; Glutamates; Glutamic Acid; Medulla Oblongata; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
N-methyl-D-aspartate receptor-mediated spontaneous activity in cerebellar granule cells in culture.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Calcium Channels; Cells, Cultured; Cerebellum; Cobalt; Dizocilpine Maleate; Glutamates; Glutamic Acid; Kynurenic Acid; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1991 |
An arthropod NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Astacoidea; Cesium; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Immunoenzyme Techniques; Interneurons; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1991 |
Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy.
Topics: Animals; Catalepsy; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haloperidol; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Valine | 1991 |
Polyamine effects upon N-methyl-D-aspartate receptor functioning: differential alteration by glutamate and glycine site antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Kinetics; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine | 1991 |
Paradoxical potentiation by low extracellular Ca2+ of acute chemical anoxic neuronal injury in cerebellar granule cell culture.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebellum; Choline; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Glutamates; Glutamic Acid; Glutathione; Iodoacetates; Iodoacetic Acid; Kynurenic Acid; Meglumine; Nerve Tissue Proteins; Neurons; Neurotoxins; Potassium; Potassium Cyanide; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium; Stimulation, Chemical | 1991 |
Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Sensitivity of rubrospinal neurons to excitatory amino acids in the rat red nucleus in vivo.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Aspartic Acid; Cats; Cerebellum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Iontophoresis; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Red Nucleus; Species Specificity | 1991 |
Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Dizocilpine Maleate; Glutamates; Glutamic Acid; Macrophages; Mice; Mice, Inbred ICR; Neuroglia; Neurons; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1991 |
Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Caffeine; Cocaine; Dopamine; Glutamates; Glutamic Acid; Heroin; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Stimulation of noradrenaline release in the cerebral cortex via presynaptic N-methyl-D-aspartate (NMDA) receptors and their pharmacological characterization.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptosomes | 1991 |
Glutamate, kainate and quisqualate enhance GABA-dependent chloride uptake in cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Cerebral Cortex; Chloride Channels; Chlorides; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, GABA-A | 1990 |
Glutamate-induced increases in intracellular Ca2+ in cultured frog tectal cells mediated by direct activation of NMDA receptor channels.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Intracellular Membranes; Ion Channels; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rana pipiens; Receptors, N-Methyl-D-Aspartate; Superior Colliculi | 1991 |
Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Cells, Cultured; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ion Channels; Kinetics; Kynurenic Acid; Models, Neurological; Piperazines; Receptors, N-Methyl-D-Aspartate | 1991 |
Stimulation of protein tyrosine phosphorylation by NMDA receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Glutamates; Glutamic Acid; Hippocampus; Immunoblotting; Kinetics; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; Tyrosine | 1991 |
Pharmacological properties of the N-methyl-D-aspartate receptor system coupled to the evoked release of gamma-[3H] aminobutyric acid from striatal neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Mice; Neurons; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
NMDA receptor blockade inhibits glutamate-induced kindling of the rat amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Glutamates; Glutamic Acid; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Acetylcholine potentiates responses to N-methyl-D-aspartate in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Kinetics; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1990 |
Masking effect of NMDA receptor antagonists on the formation of long-term potentiation (LTP) in superior colliculus slices from the guinea pig.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Denervation; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Magnesium; Mice; Nerve Degeneration; Optic Nerve; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Visual Cortex | 1990 |
Effect of L-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies.
Topics: Animals; Corpus Striatum; Dialysis; Dopamine; Glutamates; Glutamic Acid; Kinetics; Male; Membrane Potentials; Microelectrodes; Perfusion; Potassium; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1990 |
In vivo evidence for an inhibitory glutamatergic control of serotonin release in the cat caudate nucleus: involvement of GABA neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Riluzole; Serotonin; Spinal Cord; Synaptic Transmission; Tetrodotoxin; Thiazoles | 1990 |
Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Corpus Striatum; Glutamates; Glutamic Acid; Huntington Disease; Magnesium; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1990 |
Endogenous neurotransmitter activates N-methyl-D-aspartate receptors on differentiating neurons in embryonic cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Cell Differentiation; Cerebral Cortex; Electric Conductivity; Embryo, Nonmammalian; Glutamates; Glutamic Acid; Magnesium; Neurons; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Turtles | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
A topological model of the NMDA-glycine receptor model.
Topics: 2-Amino-5-phosphonovalerate; Glutamates; Glutamic Acid; Glycine; Models, Molecular; N-Methylaspartate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Cytotoxic effect of glutamate and its agonists on mouse hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Dipeptides; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Pregnancy; Quinolinic Acid; Quinolinic Acids | 1990 |
A microiontophoretic study of the role of excitatory amino acids at the afferent synapses of mammalian inner hair cells.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Male; Neurons, Afferent; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1990 |
Rhythmic bursting patterns induced in neurons of the rat nucleus tractus solitarii, in vitro, in response to N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Glutamates; Glutamic Acid; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
The glutamate-mediated release of dopamine in the rat striatum: further characterization of the dual excitatory-inhibitory function.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Caudate Nucleus; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Kinetics; Quinoxalines; Rats; Rats, Inbred Strains; Reference Values; Tetrodotoxin; Tritium; Tyrosine | 1990 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
A study of amino acid-activated currents recorded from frog motoneurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neural Conduction; Oxadiazoles; Quisqualic Acid; Rana temporaria; Valine | 1987 |
Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Oxadiazoles; Phenazocine; Potassium; Putamen; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Activation of the bilateral corticostriatal glutamatergic projection by infusion of GABA into thalamic motor nuclei in the cat: an in vivo release study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Injections; Male; Synaptic Transmission; Thalamic Nuclei; Valine | 1989 |
Evoked release of endogenous adenosine from rat cortical slices by K+ and glutamate.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Cerebral Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Potassium; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Solubilization of quisqualate-sensitive [3H]glutamate binding activity from rat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Octoxynol; Oxadiazoles; Polyethylene Glycols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Solubility | 1989 |
The development of N-methyl-D-aspartate receptors in cat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Binding, Competitive; Cats; Glutamates; Glutamic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Visual Cortex | 1989 |
Effects of intrastriatal blockade of glutamatergic transmission on the acquisition of T-maze and radial maze tasks.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Glutamates; Glutamic Acid; Male; Psychomotor Performance; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1989 |
Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1989 |
Effects of excitant amino acids on acoustic responses of inferior colliculus neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Inferior Colliculi; N-Methylaspartate; Parasympathomimetics; Rats; Rats, Inbred Strains; Valine | 1989 |
Excitatory amino acid neurotoxicity at the N-methyl-D-aspartate receptor in cultured neurons: pharmacological characterization.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Neurotoxins; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Different modulation of the binding to two phencyclidine (PCP) receptor subtypes: effects of N-methyl-D-aspartate agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Glutamates; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1989 |
Different classes of glutamate receptors mediate distinct behaviors in a single brainstem nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Brain Stem; Electric Fish; Electric Organ; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Algorithms; Animals; Aspartic Acid; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Least-Squares Analysis; Magnesium; Microelectrodes; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1989 |
Cardiovascular changes induced by the local application of glutamate-related drugs in the rat nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Glutamates; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Excitatory amino acid-receptor-mediated EPSPs in rat dorsolateral septal nucleus neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Septal Nuclei; Synaptic Transmission | 1989 |
Bicuculline- and phaclofen-sensitive components of N-methyl-D-aspartate-induced hyperpolarizations in rat dorsolateral septal nucleus neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Baclofen; Bicuculline; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Septal Nuclei; Tetrodotoxin | 1989 |
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine | 1985 |
Action of excitatory amino acids and their antagonists on hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; Iontophoresis; Manganese; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Tetrodotoxin; Valine | 1985 |
Veratrine- and glutamate-stimulated cGMP production in cultured rat neurons is differentially inhibited by imipramine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebellum; Cyclic GMP; Cytoplasmic Granules; Glutamates; Glutamic Acid; Imipramine; Neurons; Rats; Tetrodotoxin; Valine; Veratrine | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
Ia afferent excitation of motoneurones in the in vitro new-born rat spinal cord is selectively antagonized by kynurenate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Animals, Newborn; Carbachol; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Male; Motor Neurons; Muscle Spindles; Neurons, Afferent; Rats; Spinal Cord; Spinal Nerve Roots; Strychnine; Synapses; Valine | 1986 |
Synaptic excitation in cultures of mouse spinal cord neurones: receptor pharmacology and behaviour of synaptic currents.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Glutamates; Glutamic Acid; Mice; Neurons; Pipecolic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Synapses; Time Factors; Valine | 1986 |
Ionic regulation of the binding of DL-2-amino-7-phosphono-[4,5-3H]heptanoic acid to synaptosome-enriched homogenates of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding Sites; Calcium; Cerebral Cortex; Chlorides; Freezing; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
Antagonists of glutaminergic neurotransmission block retinotectal transmission in goldfish.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cyprinidae; Dipeptides; Excitatory Amino Acid Antagonists; Glutamic Acid; Goldfish; In Vitro Techniques; Kynurenic Acid; Pipecolic Acids; Retina; Superior Colliculi; Synaptic Transmission; Time Factors; Valine | 1986 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Aortic baroreceptor reflexes are mediated by NMDA receptors in caudal ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Aspartic Acid; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Medulla Oblongata; Microinjections; N-Methylaspartate; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Synaptic Transmission; Valine | 1987 |
Comparison of L-[3H]glutamate, D-[3H]aspartate, DL-[3H]AP5 and [3H]NMDA as ligands for NMDA receptors in crude postsynaptic densities from rat brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Long-term potentiation in the dentate gyrus: induction and increased glutamate release are blocked by D(-)aminophosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Depression, Chemical; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Male; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
Glutamate-evoked release of endogenous brain dopamine: inhibition by an excitatory amino acid antagonist and an enkephalin analogue.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Dopamine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1987 |
Cytoplasmic calcium elevation in hippocampal granule cell induced by perforant path stimulation and L-glutamate application.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Anticonvulsants; Aspartic Acid; Benzofurans; Calcium; Cytoplasm; Egtazic Acid; Electric Stimulation; Fluorescent Dyes; Fura-2; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neural Pathways; Tetrodotoxin; Valine | 1987 |
The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Valine | 1987 |
Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellar Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Valine | 1987 |
Non-competitive regulation of phencyclidine/sigma-receptors by the N-methyl-D-aspartate receptor antagonist D-(-)-2-amino-5-phosphonovaleric acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Glutamates; Glutamic Acid; Humans; Male; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Schizophrenia; Valine | 1987 |
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1987 |
Quinolinate is a weak excitant of cortical neurons in cell culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Magnesium; Membrane Potentials; Mice; Pyridines; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Cyanides; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; Mice; Neurons; Oxygen; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1987 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Synaptic transmission between rat cerebellar granule and Purkinje cells in dissociated cell culture: effects of excitatory-amino acid transmitter antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aspartic Acid; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Purkinje Cells; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 1988 |
Mode of binding of [3H]dibenzocycloalkenimine (MK-801) to the N-methyl-D-aspartate (NMDA) receptor and its therapeutic implication.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Kinetics; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Changes in the state of the excitatory synaptic system in the hippocampus on prolonged exposure to excitatory amino acids and antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Action Potentials; Animals; Aspartic Acid; Dipeptides; Female; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1988 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
Solubilization of rat brain phencyclidine receptors in an active binding form that is sensitive to N-methyl-D-aspartate receptor ligands.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding, Competitive; Brain Chemistry; Cell Membrane; Cholic Acid; Cholic Acids; Detergents; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Solubility; Valine | 1988 |
Evidence of N-methyl-D-aspartate receptor-mediated modulation of the aortic baroreceptor reflex in the rat nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Kainic Acid; Male; Medulla Oblongata; Oxadiazoles; Pressoreceptors; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Excitatory amino acid antagonists and endogenous aspartate and glutamate release from rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
[3H]D-2-amino-5-phosphonopentanoate as a ligand for N-methyl-D-aspartate receptors in the mammalian central nervous system.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Subcellular Fractions; Temperature; Valine | 1988 |
An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrodotoxin; Valine | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate and glutamine in mouse brain cortex.
Topics: 2-Amino-5-phosphonovalerate; 3-Mercaptopropionic Acid; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Male; Mice; N-Methylaspartate; Valproic Acid | 1988 |
Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ganglia, Spinal; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
Aspartate may be an excitatory transmitter mediating visual excitation of "sustained" but not "transient" cells in the cat retina: iontophoretic studies in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cats; Dipeptides; Glutamates; Glutamic Acid; Neurons; Neurotransmitter Agents; Retina; Synaptic Transmission; Valine | 1982 |
Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Ibotenic Acid; Interneurons; Oxazoles; Spinal Cord; Stereoisomerism; Synaptic Transmission; Valine | 1982 |
Characterization of the excitatory amino acid receptor-mediated release of [3H]acetylcholine from rat striatal slices.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Afferent Pathways; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Interneurons; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 1982 |
Role of excitatory amino acid receptors in mono- and polysynaptic excitation in the cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cats; Dipeptides; Female; Glutamates; Glutamic Acid; Male; Pipecolic Acids; Receptors, Neurotransmitter; Spinal Cord; Synaptic Transmission; Valine | 1983 |
Specific binding of [3H]+/- 2-amino-7-phosphono heptanoic acid to rat brain membranes in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Male; Mitochondria; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Fasting; Glutamates; Glutamic Acid; Male; Myoclonus; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission; Syndrome; Tremor | 1984 |
The actions of 'selective' excitatory amino acid antagonists on the crustacean neuromuscular junction.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Anomura; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Neuromuscular Junction; Norleucine; Pyridines; Synaptic Transmission; Valine | 1984 |
Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cells, Cultured; Dicarboxylic Acids; Drug Synergism; Embryo, Mammalian; Female; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Macrophages; Neuroglia; Neurons; Neurotoxins; Pregnancy; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1993 |
Single-channel activity in cultured cortical neurons of the rat in the presence of a toxic dose of glutamate.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bradykinin; Calcium; Cells, Cultured; Cerebral Cortex; Chloride Channels; Dizocilpine Maleate; Electrophysiology; Extracellular Space; Glutamates; Glutamic Acid; Ion Channels; Mice; Neurons; Potassium Channels; Rats | 1993 |
Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Ischemia; Cochlea; Cochlear Microphonic Potentials; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Male; N-Methylaspartate; Neurons, Afferent; Neurotransmitter Agents; Perfusion; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1994 |
Involvement of substance P and excitatory amino acids in aversive behavior elicited by intrathecal capsaicin.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Avoidance Learning; Biphenyl Compounds; Capsaicin; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hypnotics and Sedatives; Injections, Spinal; Male; Nociceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Substance P; Synaptic Transmission | 1994 |
Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cell Line; Cycloleucine; Dizocilpine Maleate; Glioma; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Ion Channels; Kainic Acid; Kinetics; Magnesium Chloride; N-Methylaspartate; Neurotoxins; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Signal Transduction; Tumor Cells, Cultured | 1994 |
Anatomical and electrophysiological evidence for an excitatory amino acid pathway from the thalamic mediodorsal nucleus to the prefrontal cortex in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Aspartic Acid; Axonal Transport; Electric Stimulation; Glutamic Acid; Male; Neural Conduction; Neural Pathways; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Thalamic Nuclei | 1994 |
Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cloning, Molecular; Dizocilpine Maleate; DNA; Glutamic Acid; Ion Channels; Kinetics; Kynurenic Acid; Ligands; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins | 1994 |
Thyrotropin-releasing hormone enhances excitatory postsynaptic potentials in neocortical neurons of the rat in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Stimulation; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Thyrotropin-Releasing Hormone | 1994 |
Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Ion Channels; Ligands; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1995 |
Modulation of neuropeptide FF release from rat spinal cord slices by glutamate. Involvement of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dizocilpine Maleate; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Membranes; N-Methylaspartate; Neuropeptides; Neurotoxins; Oligopeptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Calcium-dependent glutamate release during neuronal development and synaptogenesis: different involvement of omega-agatoxin IVA- and omega-conotoxin GVIA-sensitive channels.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Cells, Cultured; Fetus; Glutamic Acid; Glycine; Hippocampus; Kinetics; Magnesium; N-Methylaspartate; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Rats; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Synapses; Time Factors | 1995 |
Activation of K+ channels by stimulation of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cycloleucine; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurons; Potassium Channels; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stimulation, Chemical; Valine | 1995 |
Blockade of L-glutamate receptors in the rostral ventrolateral medulla contributes to ethanol-evoked impairment of baroreflexes in conscious rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baroreflex; Blood Pressure; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Activity-dependent responses of developing cochlear nuclear neurons to microionophoretically-applied amino acids.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Acoustic Stimulation; Action Potentials; Animals; Auditory Threshold; Bicuculline; Cats; Cochlear Nucleus; gamma-Aminobutyric Acid; Glutamic Acid; Iontophoresis; N-Methylaspartate; Neurons; Synaptic Transmission | 1995 |
Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Base Sequence; DNA, Neoplasm; Glutamates; Glutamic Acid; Glycine; Humans; Ion Channels; Kinetics; Magnesium; Membrane Potentials; Molecular Sequence Data; N-Methylaspartate; Neurons; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; RNA, Neoplasm; Sequence Homology, Amino Acid; Teratoma; Tumor Cells, Cultured | 1993 |
Glutamate dehydrogenase improves binding of [3H]CGP39653 to NMDA receptors in the autoradiographic assay.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Brain; Brain Chemistry; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
Amyloid beta-protein activates tachykinin receptors and inositol trisphosphate accumulation by synergy with glutamate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Amyloid beta-Peptides; Analgesics; Animals; Calcium; Drug Synergism; Female; Glutamates; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Kinetics; Molecular Sequence Data; Neurons; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurotransmitter; RNA, Messenger; Sodium; Substance P; Xenopus | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Effects of L-glutamate, substance P and substance P(1-7) on cardiovascular regulation in the nucleus tractus solitarius.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Molecular Sequence Data; N-Methylaspartate; Peptide Fragments; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Reference Values; Stereotaxic Techniques; Substance P | 1993 |
Hypoxic excitation of medullary vasomotor neurons in rats are not mediated by glutamate or nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Oxidoreductases; Animals; Glutamates; Glutamic Acid; Hypoxia, Brain; Injections, Spinal; Kynurenine; Male; Medulla Oblongata; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Sodium Cyanide; Sympathectomy, Chemical; Tetrodotoxin; Vasomotor System | 1993 |
Adaptive changes in the NMDA receptor complex in rat hippocampus after chronic treatment with CGP 39551.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Kynurenic Acid; Male; Norepinephrine; Phencyclidine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures.
Topics: 2-Amino-5-phosphonovalerate; Brain; Cell Death; Cells, Cultured; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Neurons; Tumor Necrosis Factor-alpha | 1994 |
N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blotting, Northern; Calcium; Cells, Cultured; Electrophysiology; Gene Expression Regulation; Genes, fos; Genes, jun; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Hippocampus; Immunohistochemistry; Kainic Acid; Kynurenic Acid; Neurons; Nifedipine; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1995 |
Presynaptic inhibition by baclofen of retinohypothalamic excitatory synaptic transmission in rat suprachiasmatic nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Male; Optic Chiasm; Optic Nerve; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Suprachiasmatic Nucleus; Synaptic Transmission | 1995 |
Presynaptic influence on the time course of fast excitatory synaptic currents in cultured hippocampal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Magnesium; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1995 |
N-methyl-D-aspartate receptors modulate neurotransmitter release and peristalsis in the guinea pig isolated colon.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Colon; Glutamic Acid; Guinea Pigs; Magnesium; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Peristalsis; Receptors, N-Methyl-D-Aspartate | 1995 |
Role of sodium and potassium ions in regulation of glucose metabolism in cultured astroglia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Bucladesine; Carbon Radioisotopes; Cells, Cultured; Corpus Striatum; Deoxyglucose; Female; Fetus; Gestational Age; Glucose; Glutamic Acid; Kinetics; Monensin; Neurons; Ouabain; Phosphorylation; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Sodium; Tetrodotoxin; Time Factors; Veratridine | 1995 |
Modulation of D-[2,3 3H]aspartate release from rat forebrain slices by non-NMDA receptor agonists and antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Kynurenic Acid; Male; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Tritium | 1995 |
Potent, orally active, competitive N-methyl-D-aspartate (NMDA) receptor antagonists are substrates for a neutral amino acid uptake system in Chinese hamster ovary cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport Systems; Amino Acids; Animals; Binding, Competitive; Biphenyl Compounds; Carrier Proteins; CHO Cells; Cricetinae; Glutamic Acid; Glycine; Kinetics; Magnetic Resonance Spectroscopy; Membranes; Models, Molecular; Molecular Conformation; Phenylalanine; Propionates; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synaptosomes; Tritium | 1995 |
Electrophysiological evidence for glutamate as a vomeronasal receptor cell neurotransmitter.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Electrophysiology; Extracellular Space; Female; Glutamic Acid; In Vitro Techniques; Neurons, Afferent; Neurotransmitter Agents; Olfactory Mucosa; Rats; Receptors, Odorant; Synapses | 1995 |
Intrathecal neuromedin C enhances mechanical nociception: possible involvement of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Sequence; Animals; Bombesin; Dose-Response Relationship, Drug; Glutamic Acid; Hindlimb; Hyperalgesia; Injections, Spinal; Male; Molecular Sequence Data; Pain Measurement; Pain Threshold; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Bombesin; Receptors, N-Methyl-D-Aspartate | 1994 |
Differential behavioral effects following microinjection of an NMDA antagonist into nucleus accumbens subregions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Environment; Exploratory Behavior; Glutamic Acid; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Glutamatergic antagonists attenuate ability of dopamine uptake blockers to increase extracellular levels of dopamine: implications for tonic influence of glutamate on dopamine release.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Chloral Hydrate; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Microdialysis; Nomifensine; Rats | 1994 |
Regulation of protein kinase C activity by taurine and beta-alanine during excitotoxicity in cat and mouse cerebellar cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; beta-Alanine; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cats; Cell Death; Cells, Cultured; Cerebellum; Electrochemistry; Glutamic Acid; Mice; Mitochondria; Protein Kinase C; Taurine | 1994 |
Effects of ionotropic excitatory amino acid receptor antagonists on glutamate transport and transport-mediated changes in extracellular excitatory amino acids in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Biological Transport; Corpus Striatum; Dicarboxylic Acids; Excitatory Amino Acids; Extracellular Space; Female; Glutamic Acid; Microdialysis; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid | 1995 |
Regulation of dopamine levels in intrastriatal grafts of fetal mesencephalic cell suspension: an in vivo voltammetric approach.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzazepines; Brain Tissue Transplantation; Cerebral Ventricles; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Female; Fetal Tissue Transplantation; Glutamic Acid; Injections, Intraventricular; Kinetics; Mesencephalon; N-Methylaspartate; Oxidopamine; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Sulpiride; Time Factors; Transplantation, Heterotopic | 1994 |
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine | 1993 |
Further evidence for multiple forms of an N-methyl-D-aspartate recognition domain in rat brain using membrane binding techniques.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Brain; Dithionitrobenzoic Acid; Dizocilpine Maleate; Ethylmaleimide; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Piperazines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Reagents; Synaptic Membranes | 1993 |
N-methyl-D-aspartate receptors contribute to guanidinosuccinate-induced convulsions in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Drug Interactions; Female; Glutamates; Glutamic Acid; Guanidines; Kainic Acid; Ketamine; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate; Seizures; Succinates | 1993 |
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Learning; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatostatin; Space Perception | 1993 |
Excitatory amino acid-induced phosphoinositide hydrolysis in Müller glia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Chickens; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Neuroglia; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Retina; Tritium | 1993 |
Synthesis and binding properties of 2-amino-5-phosphono-3-pentenoic acid photoaffinity ligands as probes for the glutamate recognition site of the NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Affinity Labels; Animals; Azides; Binding Sites; Brain; Glutamates; Glutamic Acid; Iodine Radioisotopes; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Photochemistry; Rats; Receptors, N-Methyl-D-Aspartate; Spectrometry, Mass, Fast Atom Bombardment | 1993 |
Electrophysiological properties of neurons in the rat subiculum in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurons; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1993 |
Synaptic excitation triggers oscillations during NMDA receptor activation in rat abducens motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Abducens Nerve; Animals; Dizocilpine Maleate; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Ketamine; Male; Motor Neurons; N-Methylaspartate; Oscillometry; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Biphenyl Compounds; Disease Models, Animal; Glutamates; Glutamic Acid; Immunohistochemistry; Lidocaine; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
3-Nitropropionic acid is an indirect excitotoxin to cultured cerebellar granule neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Neurons; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Enhancement of voltage-gated Ca2+ currents induced by daily stimulation of hippocampal neurons with glutamate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channels; Cell Differentiation; Cells, Cultured; Cycloheximide; Electric Conductivity; Electric Stimulation; Electrophysiology; Embryo, Mammalian; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Membrane Potentials; Neurons; Potassium Chloride; Pyramidal Cells; Rats; Time Factors | 1994 |
Glutamate-dopamine interactions in the production of pilocarpine motor seizures in the mouse.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Pilocarpine; Piperazines; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Quantal components of unitary EPSCs at the mossy fibre synapse on CA3 pyramidal cells of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Magnesium; Models, Neurological; Pyramidal Cells; Quantum Theory; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1993 |
Interaction between L-glutamate and ethanol on the central depressant properties of ethanol in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Central Nervous System Depressants; Drug Interactions; Ethanol; Glutamates; Glutamic Acid; Injections, Intraventricular; Male; Mice; Postural Balance | 1994 |
The first developing "mixed" synapses between vestibular sensory neurons mediate glutamate chemical transmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Intercellular Junctions; Lysine; Neurons, Afferent; Quinoxalines; Reflex, Vestibulo-Ocular; Synapses; Synaptic Transmission; Vestibular Nerve | 1994 |
Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Antioxidants; Astrocytes; Biological Transport; Catalase; Cells, Cultured; Cerebral Cortex; Chloromercuribenzoates; Dithionitrobenzoic Acid; Dithiothreitol; Ethylmaleimide; Free Radical Scavengers; Free Radicals; Glutamates; Glutamic Acid; Glutathione; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; p-Chloromercuribenzoic Acid; Quinoxalines; Rats; Superoxide Dismutase; Time Factors; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Aged; Aged, 80 and over; Cell Division; Cells, Cultured; Dizocilpine Maleate; DNA; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Middle Aged; N-Methylaspartate; Neuroglia; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction | 1993 |
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium | 1994 |
Spontaneous Ca2+ transients in developing hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aniline Compounds; Animals; Calcium; Calcium Channels; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Lasers; Microscopy, Fluorescence; Picrotoxin; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Tetrodotoxin; Time Factors; Xanthenes | 1994 |
Glutamate-stimulated phosphatidylinositol metabolism in the avian cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chickens; Cochlear Nucleus; Cyclopentanes; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Inositol Phosphates; Lithium Chloride; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Changes in cytosolic sodium caused by a toxic glutamate treatment of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Culture Techniques; Cytosol; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Magnesium; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Wistar; Sodium; Time Factors; Veratridine | 1994 |
Prevention by NMDA receptor antagonists of the centrally-evoked increases of cardiac inotropic responses in rabbits.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Electric Stimulation; Glutamates; Glutamic Acid; Ketamine; Kynurenic Acid; Male; Myocardial Contraction; Paraventricular Hypothalamic Nucleus; Rabbits; Receptors, N-Methyl-D-Aspartate | 1994 |
Serotonergic suppression of interhemispheric cortical synaptic potentials.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Corpus Callosum; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Functional Laterality; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin; Spiperone; Synaptic Transmission; Time Factors | 1994 |
Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Dizocilpine Maleate; Embryo, Mammalian; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
NMDA receptor function is enhanced in the hippocampus of aged rats.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Hippocampus; Kinetics; Male; Organ Specificity; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Tritium | 1994 |
[Effects of L-glutamic acid and its antagonist on spontaneous discharge of nucleus paragigantocellularis lateralis neurons in brainstem slice in rat].
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Medulla Oblongata; Microelectrodes; Neurons; Rats; Rats, Sprague-Dawley | 1994 |
Ethanol and glucose-deprivation neurotoxicity in cortical cell cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Ethanol; Glucose; Glutamates; Glutamic Acid; Neurons; Neurotoxins; Osmolar Concentration; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Release of adenosine by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Enkephalins; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Male; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Theophylline | 1994 |
Competitive NMDA receptor blockers reduce striatal glutamate accumulation in ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Extracellular Space; Glutamic Acid; In Vitro Techniques; Ischemic Attack, Transient; Male; Microdialysis; Neostriatum; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1994 |
Accelerated resensitization of the D1 dopamine receptor-mediated response in cultured cortical and striatal neurons from the rat: respective role of alpha 1-adrenergic and N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Cyclic AMP; Dopamine; Down-Regulation; Glutamic Acid; Isoproterenol; Methoxamine; Neurons; Prazosin; Prefrontal Cortex; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Visual Cortex | 1994 |
Activation of glutamate receptors in response to membrane depolarization of hair cells isolated from chick cochlea.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Calcium; Cell Membrane; Cell Polarity; Cell Separation; Cerebellum; Chelating Agents; Chickens; Egtazic Acid; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Granulocytes; Hair Cells, Auditory; Rats; Receptors, Glutamate; Ultraviolet Rays | 1994 |
Two distinct pathways are involved in the endothelin-3-evoked dopamine release from rat striatal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Interactions; Endothelins; Glutamic Acid; In Vitro Techniques; Interneurons; Male; Nifedipine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1994 |
N-methyl-D-aspartate receptor mediated component of field potentials evoked in horizontal pathways of rat motor cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Evoked Potentials, Somatosensory; Female; Glutamic Acid; Male; Motor Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate | 1994 |
Altered desensitization produces enhancement of EPSPs in neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzothiadiazines; Cerebral Cortex; Culture Techniques; Female; Glutamic Acid; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1994 |
Glutamate elicits an outward K+ current which is normally suppressed by a Ca2+/calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alkaloids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cholera Toxin; Dose-Response Relationship, Drug; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Membrane Potentials; Neurons; Pertussis Toxin; Piperazines; Potassium Channels; Protein Kinase Inhibitors; Snails; Staurosporine; Sulfonamides; Time Factors; Virulence Factors, Bordetella | 1994 |
Functional interactions between glutamate and dopamine in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Conditioning, Psychological; Corpus Striatum; Dizocilpine Maleate; Dopamine; Glutamic Acid; Kinetics; Male; Microinjections; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1994 |
Development of glutamate and NMDA sensitivity of neurons within the cochlear nuclear complex of kittens.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Acoustic Stimulation; Age Factors; Animals; Brain Mapping; Cats; Cochlear Nerve; Dose-Response Relationship, Drug; Evoked Potentials, Auditory; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
The effects of intrathecal administration of excitatory amino acid agonists and antagonists on the initiation of locomotion in the adult cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Decerebrate State; Electromyography; Glutamates; Glutamic Acid; Hindlimb; Injections, Spinal; Kainic Acid; Laminectomy; Locomotion; Motor Activity; Muscles; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Spinal Cord; Time Factors | 1993 |
Blockade of excitatory amino acid receptors in the ventrolateral medulla does not abolish the cardiovascular actions of L-glutamate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular System; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Microinjections; Quinoxalines; Rabbits; Rats; Rats, Inbred F344; Receptors, Amino Acid | 1993 |
Optical imaging of parallel fiber activation in the rat cerebellar cortex: spatial effects of excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebellar Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Glutamate antagonists in the reticular formation reduce the acoustic startle response.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Animals; Depression, Chemical; Electromyography; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Pons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Reticular Formation | 1993 |
Intrinsic proton modulation of excitatory transmission in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acid-Base Equilibrium; Animals; Benzolamide; Buffers; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Microelectrodes; Protons; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; Molecular Sequence Data; Neurons; Neurotoxins; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Strychnine; Time Factors | 1993 |
Modulation of neuronal migration by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 4-Chloromercuribenzenesulfonate; Animals; Calcium; Cell Movement; Cerebellum; Dizocilpine Maleate; Egtazic Acid; Glutamates; Glutamic Acid; Glycine; Magnesium; Mice; N-Methylaspartate; Neurons; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1993 |
An experimental arthritis model in rats: the effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Aspartic Acid; Carrageenan; Glutamates; Glutamic Acid; Injections, Intra-Articular; Kaolin; Knee Joint; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
Neuronal synchronization without calcium-dependent synaptic transmission in the hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Calcium; Circadian Rhythm; Electric Stimulation; Glutamates; Glutamic Acid; Hypothalamus; In Vitro Techniques; Male; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1993 |
Glutamate effects on calcium homeostasis in cerebellar granule cells in primary cultures grown under depolarizing and nondepolarizing conditions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Cytosol; Glutamates; Glutamic Acid; Homeostasis; Kainic Acid; Ketamine; Mice; Nerve Tissue Proteins; Neuromuscular Depolarizing Agents; Potassium; Quisqualic Acid | 1993 |
Sympathoexcitation from the rostral ventrolateral medulla is mediated by spinal NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Electric Stimulation; Female; Glutamates; Glutamic Acid; Heart Rate; Histocytochemistry; Horseradish Peroxidase; Injections, Spinal; Medulla Oblongata; Pons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Sympathetic Nervous System | 1993 |
Comparative studies on binding of 3 different ligands to the N-methyl-D-aspartate recognition domain in brain synaptic membranes treated with Triton X-100.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain Chemistry; Detergents; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Octoxynol; Piperazines; Polyethylene Glycols; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1993 |
Glutamate neurons in hypothalamus regulate excitatory transmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Evoked Potentials; Glutamates; Glutamic Acid; Hypothalamus; Microscopy, Electron; N-Methylaspartate; Neurites; Neurons; Quinoxalines; Rats; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Calcium; Cells, Cultured; Cobalt; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Mice; Neuromuscular Depolarizing Agents; Neurons; Neurotransmitter Agents; Nipecotic Acids; Nocodazole; Potassium; Pregnancy; Quinoxalines; Receptors, GABA-A; Synaptic Vesicles; Verapamil | 1993 |
Platelet-activating factor inhibits excitatory transmission in rat neostriatum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Azepines; Glutamates; Glutamic Acid; Neostriatum; Neural Inhibition; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinoxalines; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
Evidence for enhanced synaptic excitation in transplanted neostriatal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Fetal Tissue Transplantation; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Synaptic Transmission | 1993 |
Paroxysmal long-lasting depolarizations in cultured hippocampal neurons are generated by activation of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Magnesium; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1993 |
Depression of glutamatergic and GABAergic synaptic responses in striatal spiny neurons by stimulation of presynaptic GABAB receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Striatum; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Neurons; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sodium Channel Blockers; Synapses | 1993 |
Recordings of glutamate receptor channels in isolated postsynaptic densities.
Topics: 2-Amino-5-phosphonovalerate; Animals; Glutamates; Glutamic Acid; Glycine; Histocytochemistry; In Vitro Techniques; Long-Term Potentiation; Neurotransmitter Agents; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Telencephalon | 1993 |
Presynaptic actions of glutamate receptor agonists in the CA1 region of rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 1995 |
Context-dependent synaptic action of glycinergic and GABAergic inputs in the dorsal cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Cochlear Nucleus; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Membrane Potentials; Mice; Mice, Inbred CBA; Muscimol; Neural Inhibition; Neurons; Quinoxalines; Synaptic Transmission; Time Factors | 1996 |
Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells.
Topics: 2-Amino-5-phosphonovalerate; Cell Death; Cellular Senescence; Dizocilpine Maleate; Glutamic Acid; Humans; Neurons; Neurotoxins; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Teratocarcinoma; Tumor Cells, Cultured | 1995 |
Glutamate-independent long term depression in rat hippocampus by activation GABAA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Alanine; Animals; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Kynurenic Acid; Male; Muscimol; Neuronal Plasticity; Neurotoxins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A | 1996 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
Glutamate depresses release by activating non-conventional glutamate receptors at crayfish nerve terminals.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astacoidea; Axons; Calcium; Cell Membrane; Electric Conductivity; Electric Stimulation; Fura-2; Glutamic Acid; Muscles; N-Methylaspartate; Nerve Endings; Perfusion; Quisqualic Acid; Receptors, Glutamate; Synapses; Time Factors | 1996 |
Glutamate receptor ion channel properties predict vulnerability to cytotoxicity in a transfected nonneuronal cell line.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Benzothiadiazines; Cell Line; Cell Survival; Concanavalin A; Dizocilpine Maleate; DNA Primers; Evoked Potentials; Glutamic Acid; Humans; Ion Channels; Kainic Acid; Kidney; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Transfection | 1996 |
Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Weight; Circadian Rhythm; Eating; Excitatory Amino Acid Antagonists; Food Deprivation; Glutamic Acid; Hypothalamic Area, Lateral; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1996 |
Synergistic interactions between noradrenaline and glutamate in cytosolic calcium influx in cultured visual cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Calcium; Carbachol; Cells, Cultured; Cholinergic Agents; Cytosol; Drug Synergism; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Image Cytometry; Neurons; Norepinephrine; Rats; Visual Cortex | 1996 |
Intracellular calcium oscillation in cultured rat hippocampal neurons: a model for glutamatergic neurotransmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Models, Neurological; Neurons; Nicardipine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1996 |
Ion channel properties of a protein complex with characteristics of a glutamate/N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Binding Sites; Brain; Calcium; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channels; Lipid Bilayers; Liposomes; Patch-Clamp Techniques; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1996 |
Electrophysiological characterization of non-NMDA glutamate receptors on cultured intermediate lobe cells of the rat pituitary.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Pituitary Gland; Quisqualic Acid; Rats; Receptors, Glutamate | 1996 |
Muscle NMDA receptors regulate the resting membrane potential through NO-synthase.
Topics: 2-Amino-5-phosphonovalerate; Animals; Diaphragm; Glutamic Acid; Male; Membrane Potentials; Muscle Denervation; Muscles; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Glutamate and vasopressin interact to control scent marking in Syrian hamsters (Mesocricetus auratus).
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; Aggression; Animals; Arginine Vasopressin; Behavior, Animal; Cricetinae; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Male; Mesocricetus; Microinjections; Propranolol; Receptors, N-Methyl-D-Aspartate; Smell | 1996 |
Stimulation of glutamine synthetase activity by excitatory amino acids in astrocyte cultures derived from aged mouse cerebral hemispheres may be associated with non-N-methyl-D-aspartate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; N-Methylaspartate; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1996 |
Glutamate hyperexcitability and seizure-like activity throughout the brain and spinal cord upon relief from chronic glutamate receptor blockade in culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Cadmium; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hypothalamus; Membrane Potentials; Neurons; Olfactory Bulb; Organ Specificity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Seizures; Spinal Cord; Tetrodotoxin | 1996 |
Biphenyl-derivatives of 2-amino-7-phosphonoheptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonist--I. Pharmacological characterization in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Of known neurotransmitters, glutamate is the most likely to be released from chick cochlear hair cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chick Embryo; Cochlea; Diffusion; Excitatory Amino Acid Antagonists; Glutamic Acid; Hair Cells, Auditory, Inner; Ion Channels; Iontophoresis; Models, Biological; Neurotransmitter Agents; Patch-Clamp Techniques; Polylysine; Purkinje Cells; Rats; Receptors, Glutamate | 1996 |
Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Astrocytes; Biological Transport; Biomarkers; Cell Death; Cells, Cultured; Dizocilpine Maleate; Drug Synergism; Enzyme Induction; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; L-Lactate Dehydrogenase; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Sialoglycoproteins; Tumor Necrosis Factor-alpha | 1995 |
Intrathecal administration of prostaglandin E2 causes sensitization of the primary afferent neuron via the spinal release of glutamate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dinoprostone; Glutamic Acid; Hyperalgesia; Injections, Spinal; Male; Neurons, Afferent; omega-N-Methylarginine; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Spinal Cord | 1996 |
Balanced interaction of growth factors and taurine regulate energy metabolism, neuronal survival, and function of cultured mouse cerebellar cells under depolarizing conditions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Culture Media, Serum-Free; Energy Metabolism; Glutamic Acid; Growth Substances; Membrane Potentials; Mice; Mitochondria; N-Methylaspartate; Neurons; Potassium; Taurine | 1996 |
The role of excitatory neurotransmitters in seizure-induced neuronal injury in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Cerebral Cortex; Diazepam; Electroencephalography; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Male; Microdialysis; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Status Epilepticus | 1996 |
Tonic facilitation of glutamate release by presynaptic N-methyl-D-aspartate autoreceptors in the entorhinal cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dizocilpine Maleate; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Glutamic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 1996 |
Comparison of effects induced by toxic applications of kainate and glutamate by glucose deprivation on area CA1 of rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glucose; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Osmolar Concentration; Potassium; Rats; Rats, Wistar | 1996 |
Postsynaptic glutamate uptake in rat cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channel Gating; Kynurenic Acid; Membrane Potentials; Monosaccharide Transport Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin | 1996 |
Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzoates; Colforsin; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Interneurons; Kinetics; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tetrodotoxin | 1996 |
Equivalence of amplified current flowing from dendrite to soma measured by alteration of repetitive firing and by voltage clamp in layer 5 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Evoked Potentials; Glutamic Acid; Iontophoresis; Linear Models; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin | 1996 |
Resetting the biological clock: mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; Animals; Circadian Rhythm; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Gene Expression Regulation; Glutamic Acid; Light; N-Methylaspartate; NADPH Dehydrogenase; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Photic Stimulation; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Suprachiasmatic Nucleus; Time Factors; Transcription, Genetic | 1997 |
The role of excitatory amino acids in hypothermic injury to mammalian spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cell Death; Cells, Cultured; Cold Temperature; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Mice; Neurons; Receptors, N-Methyl-D-Aspartate; Reference Values; Spinal Cord; Spinal Cord Injuries | 1996 |
Involvement of non-NMDA and NMDA receptors in glutamate-induced pressor or depressor responses of the pons and medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular System; Cats; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Injections, Intraventricular; Male; Medulla Oblongata; Pons; Pressoreceptors; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System; Vagotomy | 1997 |
N-methyl-D-aspartate-mediated glutamate toxicity in the developing rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Cell Death; Cyclic GMP; Dextromethorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1997 |
Chronic pre-explant blockade of the NMDA receptor affects survival of cerebellar granule cells explanted in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apoptosis; Cell Survival; Cellular Senescence; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Neuroprotective Agents; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Binding Sites; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Ion Channel Gating; Models, Molecular; Molecular Sequence Data; Piperazines; Receptors, N-Methyl-D-Aspartate; Sequence Alignment; Sequence Homology, Amino Acid | 1997 |
Local synaptic release of glutamate from neurons in the rat hypothalamic arcuate nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium Channels; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamic Acid; Models, Neurological; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 1997 |
Spontaneous bursting activity of dopaminergic neurons in midbrain slices from immature rats: role of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Dopamine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Mesencephalon; N-Methylaspartate; Neurons; Periodicity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Regulation of cerebral microvessels by glutamatergic mechanisms.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microcirculation; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses; Vasoconstriction; Vasodilation | 1997 |
NMDA receptor antagonist blocks the bradycardic but not the pressor response to L-glutamate microinjected into the nucleus tractus solitarius (NTS) of unanesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Male; Microinjections; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Time Factors | 1997 |
Effects of N-methyl-D-aspartate-receptor blockade on high-potassium-induced neuronal death and glutamate release.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Cell Death; Excitatory Amino Acid Antagonists; Glutamic Acid; Microdialysis; Neurons; Potassium; Rats; Rats, Wistar | 1997 |
Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Ion Channel Gating; Lysophospholipids; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Glutamate; Valine | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
Effects of excitatory amino acid antagonists on dendrotoxin-induced increases in neurotransmitter release and epileptiform bursting in rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Aspartic Acid; Dizocilpine Maleate; Elapid Venoms; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Neurotoxins; Neurotransmitter Agents; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
Role of the dorso-caudal neostriatum in filial imprinting of the domestic chick: a pharmacological and autoradiographical approach focused on the involvement of NMDA-receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Chickens; Densitometry; Deoxyglucose; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorodeoxyglucose F18; Glutamic Acid; Imprinting, Psychological; Injections, Intraventricular; Ligands; N-Methylaspartate; Neostriatum; Receptors, N-Methyl-D-Aspartate | 1997 |
Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Death; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Endocannabinoids; Ethanolamine; Ethanolamines; Glutamic Acid; Ionophores; Mice; Neurons; Phencyclidine; Phosphatidylethanolamines; Polyunsaturated Alkamides; Receptors, N-Methyl-D-Aspartate; Time Factors | 1997 |
Neurones in the supraoptic nucleus of the rat are regulated by a projection from the suprachiasmatic nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Pathways; Neurons; Optic Nerve; Oxytocin; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Suprachiasmatic Nucleus; Supraoptic Nucleus; Vasopressins | 1997 |
Glutamate-dependent activation of NF-kappaB during mouse cerebellum development.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Antibody Specificity; Cell Nucleus; Cerebellum; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Injections, Intraperitoneal; Mice; Mice, Transgenic; N-Methylaspartate; Neuroprotective Agents; Neurotransmitter Agents; NF-kappa B; Transgenes | 1997 |
Proline-induced potentiation of glutamate transmission.
Topics: 2-Amino-5-phosphonovalerate; Animals; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Proline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1997 |
Currents evoked in Bergmann glial cells by parallel fibre stimulation in rat cerebellar slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cadmium; Cerebellum; Dicarboxylic Acids; Electric Stimulation; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Male; Nerve Fibers; Neuroglia; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Synapses; Tetrodotoxin | 1997 |
Endogenous glutamate levels regulate nerve growth factor mRNA expression in the rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Citrates; Dentate Gyrus; Female; Gene Expression Regulation; Glutamic Acid; Glutamine; In Situ Hybridization; Microdialysis; Nerve Growth Factors; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Synaptic Transmission | 1997 |
Evidence for the involvement of endogenous aspartate in the mediation of carotid chemoreceptor reflexes in the rostral ventrolateral medulla of the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Blood Pressure; Carotid Body; Chemoreceptor Cells; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Medulla Oblongata; Microinjections; Phenylephrine; Potassium; Rats; Rats, Wistar; Reflex; Stereotaxic Techniques | 1997 |
Dopamine inhibition: enhancement of GABA activity and potassium channel activation in hypothalamic and arcuate nucleus neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arcuate Nucleus of Hypothalamus; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1997 |
Excitatory amino acid receptors in the paraventricular hypothalamic nucleus mediate pressor response induced by carotid body chemoreceptor stimulation in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Carotid Body; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Glutamate | 1997 |
Chemical two-photon uncaging: a novel approach to mapping glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Membrane Potentials; Microscopy, Fluorescence; Photochemistry; Photons; Pyramidal Cells; Rats; Receptors, Glutamate; Ultraviolet Rays | 1997 |
Substantia nigra D1 receptors and stimulation of striatal cholinergic interneurons by dopamine: a proposed circuit mechanism.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Benzazepines; Bicuculline; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Injections, Intraperitoneal; Interneurons; Male; Microdialysis; Models, Neurological; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synaptic Transmission | 1997 |
Glutamate excitation of oxytocin neurones in vitro involves predominantly non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Enkephalin, Leucine-2-Alanine; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; In Vitro Techniques; Neurons; Oxytocin; Quinoxalines; Rats; Rats, Wistar | 1997 |
5-HT inhibits lateral entorhinal cortical neurons of the rat in vitro by activation of potassium channel-coupled 5-HT1A receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthetics, Local; Animals; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Lidocaine; Lysine; Male; Neural Inhibition; Neurons; Perforant Pathway; Potassium; Potassium Channels; Propranolol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sympatholytics | 1997 |
Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Aspartic Acid; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Glutamic Acid; L-Lactate Dehydrogenase; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitroarginine; Piperidines; Putrescine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vitamin E | 1997 |
N-methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apoptosis; Calcineurin Inhibitors; Calcium; Cells, Cultured; Cerebellum; Chromatin; Cyclosporine; Excitatory Amino Acid Antagonists; Glutamic Acid; Kinetics; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Indole Alkaloids; Isoenzymes; Male; Microscopy, Confocal; Neuronal Plasticity; Neurons; Neuroprotective Agents; Periodicity; Phospholipase C gamma; Phosphorylation; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Synapses; Type C Phospholipases; Tyrosine | 1997 |
GABA-dependent firing of glutamate-evoked action potentials at AMPA/kainate receptors in developing hypothalamic neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Magnesium; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1998 |
Activation of cerebellar climbing fibers increases cerebellar blood flow: role of glutamate receptors, nitric oxide, and cGMP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Carbon Dioxide; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Harmaline; Male; Nerve Fibers; Nitric Oxide; Nitroarginine; Oxygen; Partial Pressure; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; S-Nitroso-N-Acetylpenicillamine; Tetrodotoxin; Ultrasonography, Doppler, Transcranial | 1998 |
Manipulations of glutamatergic (N-methyl-D-aspartate receptor) neurotransmission alter the rate of photoperiodically regulated sexual maturation in the male Siberian hamster.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Cricetinae; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Gonadotropin-Releasing Hormone; Male; N-Methylaspartate; Phodopus; Photoperiod; Receptors, N-Methyl-D-Aspartate; Sexual Maturation; Synaptic Transmission; Testis | 1998 |
Glycine increases arterial pressure and augments NMDA-induced pressor responses in the dorsomedial and ventrolateral medulla of cats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cats; Dorsomedial Hypothalamic Nucleus; Drug Synergism; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Glycine; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Ventromedial Hypothalamic Nucleus | 1997 |
Activity-dependent scaling of quantal amplitude in neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Cells, Cultured; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Membrane Potentials; Neuronal Plasticity; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin; Visual Cortex | 1998 |
Functional organization of rat olfactory bulb glomeruli revealed by optical imaging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Calcium; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Image Processing, Computer-Assisted; Male; N-Methylaspartate; Olfactory Bulb; Organ Culture Techniques; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical; Tetrodotoxin | 1998 |
Somatostatin potently stimulates in vivo striatal dopamine and gamma-aminobutyric acid release by a glutamate-dependent action.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Calcium; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurotransmitter Agents; Nitric Oxide; Quinoxalines; Rats; Rats, Wistar; Sodium; Somatostatin | 1998 |
Dopamine is released spontaneously from developing midbrain neurons in organotypic culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Dopamine; Electric Stimulation; Glutamic Acid; Kinetics; Mesencephalon; Neurons; Organ Culture Techniques; Rats; Receptors, AMPA; Substantia Nigra; Tegmentum Mesencephali; Tetrodotoxin; Time Factors | 1998 |
Sensitisation to repeated withdrawal, in mice treated chronically with diazepam, is blocked by an NMDA receptor antagonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Convulsants; Diazepam; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission | 1998 |
Granule neuron regulation of Purkinje cell development: striking a balance between neurotrophin and glutamate signaling.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Proteins; Brain-Derived Neurotrophic Factor; Cell Count; Cell Differentiation; Cell Survival; Ciliary Neurotrophic Factor; Culture Media, Serum-Free; Dendrites; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Neurotrophin 3; Pregnancy; Purkinje Cells; Signal Transduction | 1998 |
Suppression of sprouting: An early function of NMDA receptors in the absence of AMPA/kainate receptor activity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Cells, Cultured; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Magnesium; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Qa-SNARE Proteins; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Synaptophysin; Synaptosomal-Associated Protein 25; Tetrodotoxin; Xenopus | 1998 |
Neurotoxic effects of low doses of glutamate on purified rat retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Calcium; Cell Death; Cell Separation; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Microscopy, Confocal; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Retinal Ganglion Cells; Xanthenes | 1998 |
Synaptically evoked dendritic action potentials in rat neocortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Dendrites; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Iontophoresis; Male; Motor Cortex; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium Channels; Somatosensory Cortex; Tetrodotoxin | 1998 |
Intrinsic and thalamic excitatory inputs onto songbird LMAN neurons differ in their pharmacological and temporal properties.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Birds; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hearing; Learning; Male; Microscopy, Confocal; Neostriatum; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus; Vocalization, Animal | 1998 |
Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antimycin A; Cell Respiration; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Glutathione; Mitochondria; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Radiation-Protective Agents; Rats; Rats, Wistar; Rotenone; Succinic Acid; Uncoupling Agents | 1998 |
Dopamine facilitates long-term depression of glutamatergic transmission in rat prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Calcium; Chelating Agents; Dopamine; Dopamine Agonists; Dopamine Antagonists; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Long-Term Potentiation; Male; Membrane Potentials; Neuronal Plasticity; Prefrontal Cortex; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Sulpiride; Synaptic Membranes; Synaptic Transmission | 1998 |
Sensitivity and density of glutamate receptor subtypes in the hippocampal formation are altered in pentylenetetrazole-kindled rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Chemistry; Convulsants; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Inositol Phosphates; Kindling, Neurologic; Male; Neuroprotective Agents; Pentylenetetrazole; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
Endogenous NMDA-receptor activation regulates glutamate release in cultured spinal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses; Tetrodotoxin; Time Factors | 1998 |
Characterization of the N-methyl-D-aspartate (NMDA) receptor in the embryonic chick brain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Blotting, Western; Brain; Brain Chemistry; Calcium; Cell Count; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Immunohistochemistry; Kainic Acid; Neurons; Receptors, N-Methyl-D-Aspartate; Telencephalon | 1998 |
Analysing functional connectivity in brain slices by a combination of infrared video microscopy, flash photolysis of caged compounds and scanning methods.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electric Stimulation; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Microscopy, Video; Photolysis; Quinoxalines; Rats; Receptors, Glutamate; Somatosensory Cortex; Tetrodotoxin | 1998 |
N-methyl-D-aspartate antagonists, glutamate release inhibitors, 4-aminopyridine at neuromuscular transmission.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Diaphragm; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Muscle Contraction; Neuromuscular Junction; Phrenic Nerve; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Role of Na+/Ca2+ exchange in regulation of neuronal Ca2+ homeostasis requires re-evaluation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cell Survival; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamic Acid; Homeostasis; Hydrogen-Ion Concentration; Meglumine; Memantine; Mitochondria; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium-Calcium Exchanger | 1998 |
IL-1beta increases norepinephrine level in rat frontal cortex: involvement of prostanoids, NO, and glutamate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Frontal Lobe; Glutamic Acid; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Prostaglandins; Rats; Rats, Wistar; Sialoglycoproteins | 1998 |
Early synaptogenesis in vitro: role of axon target distance.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Axons; Bicuculline; Calcium; Cell Count; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Hypothalamus; Indicators and Reagents; Luminescent Proteins; Neurites; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Synaptic Vesicles; Synaptophysin; Tetrodotoxin | 1998 |
Evidence that excitatory amino acid receptors within the temporomandibular joint region are involved in the reflex activation of the jaw muscles.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Brain Stem; Dose-Response Relationship, Drug; Electromyography; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Jaw; Kainic Acid; Lidocaine; Male; Masseter Muscle; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Trigeminal Nerve | 1998 |
Glutamatergic regulation of basal and stimulus-activated dopamine release in the prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dopamine; Glutamic Acid; Handling, Psychological; Injections, Intraventricular; Isoquinolines; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Tetrazoles; Ventral Tegmental Area; Wakefulness | 1998 |
VIP and PACAP potentiate the action of glutamate on BDNF expression in mouse cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Astrocytes; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Mice; Neuronal Plasticity; Neurons; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Vasoactive Intestinal Peptide | 1998 |
Mediodorsal thalamus plays a critical role in the development of limbic motor seizures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Brain Mapping; Carbon Radioisotopes; Deoxyglucose; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Muscimol; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Thalamus; Time Factors; Vigabatrin | 1998 |
Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calbindin 1; Calbindins; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cyclic N-Oxides; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Ganglia, Spinal; Glutamic Acid; Glutathione; Kynurenic Acid; Mice; Motor Neurons; Mutagenesis; Nerve Tissue Proteins; Neurotoxins; Nitrogen Oxides; Oxidative Stress; Receptors, AMPA; S100 Calcium Binding Protein G; Spider Venoms; Spinal Cord; Superoxide Dismutase; Synapses | 1998 |
Involvement of the glutamate transporter and the sodium-calcium exchanger in the hypoxia-induced increase in intracellular Ca2+ in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Bepridil; Biological Transport; Calcium; Calcium Channel Blockers; Chelating Agents; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Fura-2; Glutamic Acid; Hippocampus; Hypoxia; Neurotransmitter Uptake Inhibitors; Organ Culture Techniques; Pyrrolidines; Rats; Rats, Wistar; Sodium; Sodium-Calcium Exchanger | 1998 |
A microdialysis study investigating the mechanisms of hydroxyl radical formation in rat striatum exposed to glutamate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Microdialysis; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Quinacrine; Rats; Rats, Sprague-Dawley | 1998 |
A purinergic component of the excitatory postsynaptic current mediated by P2X receptors in the CA1 neurons of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Neurons; Organ Culture Techniques; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Stimulation, Chemical | 1998 |
Arachidonic acid as a messenger for the expression of long-term potentiation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anthracenes; Arachidonic Acid; Chromatography, High Pressure Liquid; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Guinea Pigs; Hippocampus; Long-Term Potentiation; Presynaptic Terminals; Quinoxalines; Rats; Synaptic Transmission | 1999 |
Glutamate and gamma-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Morpholines; Nerve Fibers; Organophosphorus Compounds; Pyramidal Cells; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Synapses | 1999 |
AMPA receptor activation of area postrema neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cerebral Ventricles; Cytosol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Osmolar Concentration; Quinoxalines; Rats; Receptors, AMPA | 1999 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Glutamate receptors in the cingulate cortex, hippocampus, and cerebellar vermis of alcoholics.
Topics: 2-Amino-5-phosphonovalerate; Aged; Alcoholism; Cerebellar Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Middle Aged; Receptors, Glutamate | 1999 |
Cellular mechanisms underlying spontaneous interictal spikes in an acute model of focal cortical epileptogenesis.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Acute Disease; Animals; Bicuculline; Brain; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Functional Laterality; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Lidocaine; Membrane Potentials; Reaction Time; Synaptic Transmission | 1999 |
Modulation of the audiogenic seizure network by noradrenergic and glutamatergic receptors of the deep layers of superior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Adrenergic alpha-Agonists; Animals; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Inferior Colliculi; Male; Microinjections; Norepinephrine; Phenylephrine; Rats; Rats, Mutant Strains; Receptors, Adrenergic; Receptors, N-Methyl-D-Aspartate; Reticular Formation; Superior Colliculi | 1999 |
Cardiovascular responses to microinjections of excitatory amino acids into the area postrema of the rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Cerebral Ventricles; Cycloleucine; Decerebrate State; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Tachycardia; Urethane | 1999 |
The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Enzyme Activation; Estrogens; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Neuroprotective Agents; Protein-Tyrosine Kinases; Rats; Signal Transduction | 1999 |
Group I metabotropic glutamate receptors mediate phospholipase D stimulation in rat cultured astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Benzoates; Carcinogens; Cerebellum; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neurons; Neuroprotective Agents; Norepinephrine; Phospholipase D; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathomimetics; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1999 |
Properties of NMDA receptors in rat spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Animals, Newborn; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Magnesium; Male; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Ferrous iron modulates quinolinate-mediated [3H]MK-801 binding to rat brain synaptic membranes in the presence of glycine and spermidine.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Binding Sites; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ferrous Compounds; Glutamic Acid; Glycine; Inhibitory Concentration 50; Kynurenic Acid; Male; Quinolinic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Synaptic Membranes | 1999 |
Dissecting dendrite dynamics.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Dendrites; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Microscopy, Fluorescence; Neurons; Pseudopodia; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Membranes | 1999 |
Activation of NMDA receptors protects against glutamate neurotoxicity in the retina: evidence for the involvement of neurotrophins.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Nerve Growth Factors; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; Retina | 1999 |
Activation of NMDA receptors in the suprachiasmatic nucleus produces light-like phase shifts of the circadian clock in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain Chemistry; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Lighting; Male; Mesocricetus; Microinjections; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus; Synaptic Transmission | 1999 |
GABAB receptor-mediated regulation of glutamate-activated calcium transients in hypothalamic and cortical neuron development.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Calcium; Cells, Cultured; Cerebral Cortex; Cytarabine; Drug Synergism; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Hypothalamus, Middle; Membrane Potentials; Neurons; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Tetrodotoxin; Virulence Factors, Bordetella | 1999 |
Apoptotic cell death and caspase-3 activation induced by N-methyl-D-aspartate receptor antagonists and their prevention by insulin-like growth factor I.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Calcium; Caspase 3; Caspases; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dizocilpine Maleate; DNA Fragmentation; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutamic Acid; Insulin-Like Growth Factor I; Neurons; Protein Synthesis Inhibitors; Rats; Receptors, N-Methyl-D-Aspartate | 1999 |
Modulation of the mesolimbic dopamine system by glutamate: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Binding, Competitive; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Homovanillic Acid; Limbic System; Male; Microdialysis; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 1999 |
Synaptically released glutamate reduces gamma-aminobutyric acid (GABA)ergic inhibition in the hippocampus via kainate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hippocampus; Kynurenic Acid; Receptors, AMPA; Receptors, Kainic Acid; Seizures | 1999 |
Short-term block of Na+/K+-ATPase in neuro-glial cell cultures of cerebellum induces glutamate dependent damage of granule cells.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Binding, Competitive; Calcium; Cells, Cultured; Cerebellum; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium; N-Methylaspartate; Neuroglia; Ouabain; Rats; Rats, Wistar; Rhodamine 123; Sodium-Potassium-Exchanging ATPase; Xanthenes | 1999 |
Characterization of spontaneous excitatory synaptic currents in newt retinal bipolar cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzothiadiazines; Computer Simulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Models, Neurological; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Salamandridae; Synaptic Transmission | 1999 |
Effects of lesions to the glutamatergic afferents to the nucleus accumbens in the modulation of reactivity to spatial and non-spatial novelty in mice.
Topics: Afferent Pathways; Amygdala; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Hippocampus; Ibotenic Acid; Injections; Limbic System; Mice; Models, Neurological; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Spatial Behavior; Valine | 1999 |
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamates; Glutamic Acid; Male; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 1999 |
Prolonged enhancement of AP-1 DNA binding by blockade of glutamate uptake in cultured neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biological Transport; Cells, Cultured; Cerebellum; Dicarboxylic Acids; Dimerization; Dizocilpine Maleate; DNA-Binding Proteins; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Neurotoxins; Neurotransmitter Uptake Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Transcription Factor AP-1 | 1999 |
Mauthner cell-initiated electromotor behavior is mediated via NMDA and metabotropic glutamatergic receptors on medullary pacemaker neurons in a gymnotid fish.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Clocks; Electric Fish; Electric Organ; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Medulla Oblongata; Motor Activity; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
NMDA receptor-mediated control of GABA release from neurointermediate lobes of female and male rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Estradiol; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Ovariectomy; Pituitary Gland, Posterior; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1999 |
Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antioxidants; Cell Membrane Permeability; Chlorides; Chromans; Deferoxamine; Extracellular Space; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Microscopy, Confocal; Muscimol; Nipecotic Acids; Oxidative Stress; Pyramidal Cells; Quinolinium Compounds; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tiagabine | 1999 |
Substrate turnover by transporters curtails synaptic glutamate transients.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Benzothiadiazines; Cells, Cultured; Evoked Potentials; Glutamic Acid; Hippocampus; Membrane Potentials; N-Methylaspartate; Neuroglia; Neurons; Oocytes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Xenopus laevis | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Activation of spinal N-methyl-D-aspartate receptors stimulates a nitric oxide/cyclic guanosine 3,5-monophosphate/glutamate release cascade in nociceptive signaling.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanylate Cyclase; Male; Microdialysis; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; Synaptic Transmission | 1999 |
Role of membrane conductances and protein synthesis in subjective day phase advances of the hamster circadian clock by neuropeptide Y.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anisomycin; Circadian Rhythm; Cricetinae; Cycloheximide; Electric Conductivity; Excitatory Amino Acid Antagonists; Glutamic Acid; Ionophores; Male; Membrane Potentials; Mesocricetus; Nerve Tissue Proteins; Neurons; Neuropeptide Y; Organ Culture Techniques; Patch-Clamp Techniques; Potassium; Potassium Channels; Protein Synthesis Inhibitors; Sodium; Sodium Channels; Suprachiasmatic Nucleus; Tetraethylammonium; Valinomycin | 1999 |
Extracellular adenosine 5'-triphosphate plus activation of glutamatergic receptors induces long-term potentiation in CA1 neurons of guinea pig hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Calcium; Drug Combinations; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Neurons; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Methionine sulfoximine shows excitotoxic actions in rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Cerebral Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control of feeding behavior.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Feeding Behavior; Food Deprivation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamic Area, Lateral; Injections; Male; Muscimol; Neural Inhibition; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1999 |
Developmental changes in the neurotransmitter regulation of correlated spontaneous retinal activity.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Bicuculline; Cholinergic Fibers; Excitatory Amino Acid Antagonists; Ferrets; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glycine Agents; Interneurons; Periodicity; Quinoxalines; Retina; Retinal Ganglion Cells; Strychnine; Synaptic Transmission; Vision, Ocular; Visual Pathways | 2000 |
Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channel Blockers; Cycloleucine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Lumbosacral Region; Motor Neurons; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spider Venoms; Spinal Cord | 2000 |
Properties of miniature glutamatergic EPSCs in neurons of the locomotor regions of the developing zebrafish.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Larva; Motor Activity; Motor Neurons; Neurons; Picrotoxin; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Synapses; Tetrodotoxin; Zebrafish | 2000 |
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 2000 |
Participation of NMDA and kainate receptors of paraventricular nucleus in cardiovascular responses to glutamate receptor agonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hemodynamics; Kainic Acid; Male; Microinjections; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2000 |
Reciprocal modulation of glutamate and GABA release may underlie the anticonvulsant effect of phenytoin.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Brain Chemistry; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Inhibition; Patch-Clamp Techniques; Phenytoin; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 2000 |
Bradycardic and hypotensive responses to microinjection of L-glutamate into the lateral aspect of the commissural NTS are blocked by an NMDA receptor antagonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Bradycardia; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypotension; Male; Microinjections; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 2000 |
Development of glutamatergic synaptic activity in cultured spinal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fetus; Glutamic Acid; Magnesium; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses; Tetrodotoxin | 2000 |
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bicuculline; Calcium; Calcium Channels; Cesium; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Methylmalonic and propionic acids increase the in vitro incorporation of 32P into cytoskeletal proteins from cerebral cortex of young rats through NMDA glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Cytoskeletal Proteins; Glutamic Acid; In Vitro Techniques; Methylmalonic Acid; N-Methylaspartate; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Propionates; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
[Effects of L-glutamic acid, gamma-aminobutyric acid and their respective antagonists on spontaneous discharge of nucleus paragigantocellularis lateralis neurons in rats].
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electrophysiology; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Medulla Oblongata; Neurons; Rats; Rats, Sprague-Dawley | 1997 |
Native N-methyl-D-aspartate receptors containing NR2A and NR2B subunits have pharmacologically distinct competitive antagonist binding sites.
Topics: 2-Amino-5-phosphonovalerate; Animals; Binding Sites; Brain; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Glutamate does not mediate acute neuronal damage after spreading depression induced by O2/glucose deprivation in the hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Ischemia; Cortical Spreading Depression; Evoked Potentials; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Neurotoxins; Oxygen; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Temperature | 2000 |
NMDA receptor-mediated control of protein synthesis at developing synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Electrophoresis, Gel, Two-Dimensional; Glutamic Acid; Isoelectric Point; Molecular Weight; N-Methylaspartate; Peptide Elongation Factor 2; Phosphorylation; Precipitin Tests; Protein Biosynthesis; Proteins; Rats; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Superior Colliculi; Synapses; Synaptosomes; Time Factors | 2000 |
Hearing loss and glutamate efflux in the perilymph following transient hindbrain ischemia in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Animals; Audiometry, Evoked Response; Cerebrovascular Circulation; Cochlear Nerve; Deafness; Dendrites; Excitatory Amino Acid Antagonists; Gerbillinae; Glutamic Acid; Ischemic Attack, Transient; Neurons; Perilymph; Quinoxalines; Rhombencephalon | 2000 |
Modulation of extracellular glutamate and pressor response to muscle contraction during NMDA-receptor blockade in the rostral ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glutamic Acid; Heart Rate; Medulla Oblongata; Muscle Contraction; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Postfusional regulation of cleft glutamate concentration during LTP at 'silent synapses'.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antihypertensive Agents; Benzothiadiazines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; Glutamic Acid; Long-Term Potentiation; Patch-Clamp Techniques; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 2000 |
Brevetoxin-induced autocrine excitotoxicity is associated with manifold routes of Ca2+ influx.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Autocrine Communication; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cerebellum; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Marine Toxins; Neurons; Neurotoxins; Nifedipine; Oxocins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Thiourea; Xanthenes | 2000 |
NMDA spikes in basal dendrites of cortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cerebral Cortex; Computer Simulation; Dendrites; Electrophysiology; Evoked Potentials; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Calcium; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kindling, Neurologic; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Phenylacetates; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Sodium; Tetrodotoxin; Up-Regulation | 2000 |
Modulation of GABAergic signaling among interneurons by metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neural Inhibition; Propionates; Quinoxalines; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission | 2000 |
Laminar characteristics of functional connectivity in rat barrel cortex revealed by stimulation with caged-glutamate.
Topics: Animals; Brain Mapping; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Neural Pathways; Neurons; Photic Stimulation; Photolysis; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Somatosensory Cortex; Synapses; Time Factors; Valine; Vibrissae | 2000 |
Ischemia but not anoxia evokes vesicular and Ca(2+)-independent glutamate release in the dorsal vagal complex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Ischemia; Brain Stem; Calcium; Chloride Channels; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hypoglycemic Agents; Hypoxia, Brain; In Vitro Techniques; Indoles; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Sulfonylurea Compounds; Synaptic Transmission; Tolbutamide; Vagus Nerve | 2000 |
Acute decrease in net glutamate uptake during energy deprivation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Brain Ischemia; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidines; Quinoxalines; Rats | 2000 |
Prolonged synaptic currents and glutamate spillover at the parallel fiber to stellate cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Dicarboxylic Acids; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Nerve Fibers; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 2000 |
Impaired escape performance and enhanced conditioned fear in rats following exposure to an uncontrollable stressor are mediated by glutamate and nitric oxide in the dorsal raphe nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Conditioning, Psychological; Electroshock; Enzyme Inhibitors; Escape Reaction; Fear; Glutamic Acid; Helplessness, Learned; Male; Models, Neurological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin | 2000 |
Distribution of functional glutamate and GABA receptors on hippocampal pyramidal cells and interneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Polarity; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Lysine; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Rats; Receptors, GABA; Receptors, Glutamate; Synapses | 2000 |
Functional role of NMDA autoreceptors in olfactory mitral cells.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoreceptors; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Neurons, Afferent; Nifedipine; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2000 |
Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Calcium; Cells, Cultured; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2000 |
Systemic nicotine stimulates dopamine release in nucleus accumbens: re-evaluation of the role of N-methyl-D-aspartate receptors in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Ventral Tegmental Area | 2000 |
Afferent ingrowth and onset of activity in the rat trigeminal nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Biotin; Cadmium; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Neurons, Afferent; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Trigeminal Nuclei; Vibrissae | 2000 |
Enflurane directly depresses glutamate AMPA and NMDA currents in mouse spinal cord motor neurons independent of actions on GABAA or glycine receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Inhalation; Animals; Chloride Channels; Depression, Chemical; Drug Interactions; Enflurane; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Motor Neurons; Receptors, Amino Acid; Receptors, AMPA; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission; Tetrodotoxin | 2000 |
Interferon-alpha inhibits long-term potentiation and unmasks a long-term depression in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Genistein; Glutamic Acid; Hippocampus; Immunologic Factors; In Vitro Techniques; Interferon-alpha; Long-Term Potentiation; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Pyramidal Cells; Rats; Receptors, GABA-A; Synapses | 2000 |
A brain slice model for in vitro analyses of astrocytic gap junction and connexin43 regulation: actions of ischemia, glutamate and elevated potassium.
Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Brain; Connexin 43; Gap Junctions; Glutamic Acid; Hypoxia-Ischemia, Brain; In Vitro Techniques; Models, Neurological; Phosphorylation; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Impairment of the Ca2+-permeable AMPA/kainate receptors by lead exposure in organotypic rat hippocampal slice cultures.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Animals, Suckling; Biological Transport; Calcium; Cobalt; Glutamic Acid; Hippocampus; Lead; N-Methylaspartate; Organ Culture Techniques; Permeability; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 2000 |
Neuroprotective properties of nootropic dipeptide GVS-111 in in vitro oxygen-glucose deprivation, glutamate toxicity and oxidative stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Ischemia; Cells, Cultured; Cerebellum; Dipeptides; Glucose; Glutamic Acid; Neurons; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Oxygen; Piracetam; Rats; Rats, Wistar | 2000 |
Dendritic glutamate-induced bursting in prefrontal pyramidal cells: role of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Glutamic Acid; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Kappa opioid receptor inhibition of glutamatergic transmission in the nucleus accumbens shell.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzeneacetamides; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Neural Inhibition; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptic Transmission | 2001 |
Pharmacological characterization of threo-3-methylglutamic acid with excitatory amino acid transporters in native and recombinant systems.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Carrier Proteins; Cell Line; Cerebellum; Cerebral Cortex; Dogs; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Excitatory Amino Acid Transporter 4; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Kidney; Kinetics; Neurotransmitter Uptake Inhibitors; Oocytes; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurotransmitter; Recombinant Fusion Proteins; Symporters; Synaptosomes; Xenopus laevis | 2001 |
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Cyclosporine; Electron Transport; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Membrane Potentials; Mitochondria; Models, Biological; NAD; NADH, NADPH Oxidoreductases; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligomycins; omega-N-Methylarginine; Permeability; Rats; Rats, Wistar; Receptors, Glutamate; Rotenone; Single-Blind Method; Succinate Cytochrome c Oxidoreductase | 2001 |
Glutamate does not play a major role in controlling bone growth.
Topics: 2-Amino-5-phosphonovalerate; Alveolar Bone Loss; Amino Acid Transport System X-AG; Animals; Animals, Newborn; ATP-Binding Cassette Transporters; Biological Transport; Bone Diseases, Metabolic; Bone Remodeling; Bone Resorption; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Femur; Glutamic Acid; Glycine; Humerus; Mandible; Mice; Mice, Knockout; Models, Animal; N-Methylaspartate; Osteoblasts; Osteoclasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
Unipolar brush cells form a glutamatergic projection system within the mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calbindin 2; Cell Size; Cerebellar Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Interneurons; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; Nerve Fibers; Neural Pathways; Organ Culture Techniques; Patch-Clamp Techniques; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; S100 Calcium Binding Protein G; Tissue Embedding | 2001 |
Early onset of glutamatergic and GABAergic synaptic activity in the visual layers of the rodent superior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Inbred C57BL; Nicotinic Antagonists; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Species Specificity; Superior Colliculi; Synaptic Transmission; Tubocurarine | 2001 |
Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Carrier Proteins; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; GTP-Binding Proteins; Hypothalamic Area, Lateral; Hypothalamic Hormones; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Melanins; Neurons; Neuropeptides; Orexin Receptors; Orexins; Patch-Clamp Techniques; Pituitary Hormones; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Glutamate; Receptors, Neuropeptide; Sodium; Synaptic Transmission; Tetrodotoxin | 2001 |
Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amino Acids; Aminobutyrates; Animals; Bicuculline; Drug Design; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Substantia Nigra; Xanthenes | 2001 |
Electrophysiological characterization of "giant" cells in stratum radiatum of the CA3 hippocampal region.
Topics: 2-Amino-5-phosphonovalerate; 3,3'-Diaminobenzidine; Action Potentials; Animals; Axons; Bicuculline; Calcium; Cesium; Chlorides; Choline; Cyclopropanes; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Immunoenzyme Techniques; Microscopy, Video; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2001 |
Stress-induced increase in extracellular dopamine in striatum: role of glutamatergic action via N-methyl-D-aspartate receptors in substantia nigra.
Topics: Animals; Dopamine; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Hydrazines; Male; Microdialysis; Neostriatum; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Substantia Nigra; Valine | 2001 |
Effect of lactate on the synaptic potential, energy metabolism, calcium homeostasis and extracellular glutamate concentration in the dentate gyrus of the hippocampus from guinea-pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Dentate Gyrus; Energy Metabolism; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycolysis; Guinea Pigs; Homeostasis; Intracellular Fluid; Lactic Acid; Neurons; Nimodipine; Organ Culture Techniques; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Theophylline | 2001 |
Bidirectional modulation of basal forebrain N-methyl-D-aspartate receptor function differentially affects visual attention but not visual discrimination performance.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Attention; Basal Nucleus of Meynert; Cerebral Cortex; Cholinergic Fibers; Cues; Discrimination Learning; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; N-Methylaspartate; Neural Pathways; Pattern Recognition, Visual; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
MAP2 phosphorylation and visual plasticity in Xenopus.
Topics: Aging; Animals; Dendrites; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Glutamic Acid; Immunoblotting; Microtubule-Associated Proteins; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Valine; Vision, Binocular; Visual Pathways; Xenopus laevis | 2001 |
Nicotine-induced enhancement of glutamatergic and GABAergic synaptic transmission in the mouse amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Female; Fetus; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Olfactory Bulb; Pregnancy; Synaptic Transmission | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Exogenous glutamate induces short and long-term potentiation in the rat medial vestibular nuclei.
Topics: 2-Amino-5-phosphonovalerate; Animals; Diterpenes; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Ginkgolides; Glutamic Acid; Indans; Lactones; Long-Term Potentiation; Membrane Potentials; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Rats; Rats, Wistar; Vestibular Nuclei | 2001 |
Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Central Nervous System Stimulants; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Kinetics; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, Kainic Acid; Synapses; Synaptic Transmission; Temperature; Thalamus | 2001 |
Glomerulus-specific synchronization of mitral cells in the olfactory bulb.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; N-Methylaspartate; Olfactory Bulb; Olfactory Receptor Neurons; Periodicity; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell | 2001 |
Absence of evidence is not evidence of absence. Redundancy blocks determination of cause and effect.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Bone Resorption; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate; Osteoblasts; Osteogenesis; Receptors, N-Methyl-D-Aspartate | 2001 |
Glutamate and GABA mediate suprachiasmatic nucleus inputs to spinal-projecting paraventricular neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Microspheres; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord; Suprachiasmatic Nucleus | 2001 |
Oxidative glutamate toxicity can be a component of the excitotoxicity cascade.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System y+; Animals; Carrier Proteins; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Cystine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Mice; Mice, Inbred BALB C; Neurons; Oxidative Stress; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 2001 |
Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of a novel antagonist PPDC.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Glycine; Hot Temperature; Piperidines; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Excitation of the pedunculopontine tegmental NMDA receptors induces wakefulness and cortical activation in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sleep; Tegmentum Mesencephali; Wakefulness | 2001 |
Excitatory synaptic currents in lumbosacral parasympathetic preganglionic neurons elicited from the lateral funiculus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Autonomic Fibers, Preganglionic; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Lumbosacral Region; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Spinal Cord; Synapses | 2001 |
NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoreceptors; Calcium; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Neurons; Piperidines; Presynaptic Terminals; Quinolinic Acids; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2001 |
Aldrin-induced stimulation of locomotor activity and brain regional glutamate.
Topics: 2-Amino-5-phosphonovalerate; Aldrin; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Insecticides; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 2001 |
Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat.
Topics: Afferent Pathways; Animals; Cell Count; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Inflammation; Male; Muscle, Skeletal; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Skin; Synaptic Transmission; Turpentine; Valine | 2001 |
The expression of cerebellar LTD in culture is not associated with changes in AMPA-receptor kinetics, agonist affinity, or unitary conductance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Mice; Phorbol Esters; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
NMDA-mediated increase in renal sympathetic nerve discharge within the PVN: role of nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Kidney; Microinjections; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2001 |
NMDA and muscarinic blockade in the perirhinal cortex impairs object discrimination in rats.
Topics: Acetylcholine; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memory, Short-Term; Muscarinic Antagonists; Neurons; Parahippocampal Gyrus; Pattern Recognition, Visual; Photic Stimulation; Rats; Rats, Long-Evans; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Scopolamine; Synaptic Transmission; Valine | 2001 |
Involvement of spinal N-methyl-D-aspartate receptors in capsaicin-induced in vivo release of substance P in the rat dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Nerve Fibers; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance P; Synapses; Synaptic Transmission | 2001 |
The effects of N-methyl-D-aspartate antagonist 2-amino-7-phosphonoheptanoic acid microinfusions into the adult male rat substantia nigra pars reticulata are site-specific.
Topics: 2-Amino-5-phosphonovalerate; Animals; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flurothyl; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Substantia Nigra; Synaptic Transmission | 2001 |
Synergistic enhancement of glutamate-mediated responses by serotonin and forskolin in adult mouse spinal dorsal horn neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenylyl Cyclases; Animals; Colforsin; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Posterior Horn Cells; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Serotonin; Valine | 2002 |
Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hindlimb; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Mutant Strains; Morphine; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Pain Measurement; Piperazines; Piperidines; Pyrrolidinones; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Spinal Cord; Subarachnoid Space | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Glutamate mediated responses in isolated trachea preparations from control and ovalbumin sensitized guinea-pigs.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; N-Methylaspartate; Ovalbumin; Receptors, Glutamate; Trachea | 2002 |
D-AP5 blocks the increase of intracellular free Ca2+ induced by glutamate in isolated cochlear IHCs.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; In Vitro Techniques; Receptors, N-Methyl-D-Aspartate | 2002 |
Activity-dependent expression of simultaneous glutamatergic and GABAergic neurotransmission from the mossy fibers in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kindling, Neurologic; Mossy Fibers, Hippocampal; Perforant Pathway; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission | 2002 |
NMDA receptor activation mediates hydrogen peroxide-induced pathophysiology in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Male; Organ Culture Techniques; Oxidants; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2002 |
Further characterization of the molecular interaction between PSD-95 and NMDA receptors: the effect of the NR1 splice variant and evidence for modulation of channel gating.
Topics: 2-Amino-5-phosphonovalerate; Binding, Competitive; Cell Line; Dizocilpine Maleate; DNA, Recombinant; Excitatory Amino Acid Antagonists; Genetic Variation; Glutamic Acid; Glycine; Humans; Ion Channel Gating; Nerve Tissue Proteins; Prosencephalon; Receptors, N-Methyl-D-Aspartate | 2002 |
Involvement of NMDA receptors in the pressor response to microinjection of 5-HT3 agonist into the NTS of awake rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Receptor Agonists; Sodium Chloride; Solitary Nucleus | 2002 |
Blockade of NMDA-receptors or calcium-channels attenuates the ischaemia-evoked efflux of glutamate and phosphoethanolamine and depression of neuronal activity in rat organotypic hippocampal slice cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium Channel Blockers; Cell Hypoxia; Deoxyglucose; Diltiazem; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Ischemia; Kinetics; Neurons; Organ Culture Techniques; Phosphatidylethanolamines; Potassium Cyanide; Rats; Receptors, N-Methyl-D-Aspartate | 2002 |
Differential involvement of cortical muscarinic and NMDA receptors in short- and long-term taste aversion memory.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Avoidance Learning; Cerebral Cortex; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium Chloride; Male; Memory, Short-Term; Models, Neurological; Muscarinic Antagonists; Nerve Net; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Scopolamine; Synaptic Transmission; Taste | 2002 |
Fast-acting excitatory amino acids are involved in the enhancement of the aversiveness of the electrical stimulation of the inferior colliculus by systemic injections of muscimol.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Inferior Colliculi; Injections, Intraperitoneal; Male; Microinjections; Muscimol; Rats; Rats, Wistar | 2002 |
Characterization of striatal activity in conscious rats: contribution of NMDA and AMPA/kainate receptors to both spontaneous and glutamate-driven firing.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corpus Striatum; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Iontophoresis; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2003 |
Glutamatergic and serotonergic mechanisms in the dorsal facial area for common carotid artery blood flow control in the cat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Blood Flow Velocity; Blood Pressure; Carotid Artery, Common; Cats; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Glutamates; Glutamic Acid; Heart Rate; Ketanserin; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, AMPA; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Evidence against the presence of NMDA receptors at a central glutamatergic synapse in leeches.
Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Central Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kynurenic Acid; Leeches; Motor Neurons; N-Methylaspartate; Neurons, Afferent; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex; Synapses; Synaptic Transmission | 2002 |
Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Homovanillic Acid; Methamphetamine; Microdialysis; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Valine | 2003 |
Critical role for ventral tegmental glutamate in preference for a cocaine-conditioned environment.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cocaine; Cocaine-Related Disorders; Cues; Environment; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 2003 |
Involvement of glutamate in gastrointestinal vago-vagal reflexes initiated by gastrointestinal distention in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Digestive System Physiological Phenomena; Duodenum; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Solitary Nucleus; Stomach; Vagus Nerve | 2003 |
Glucocorticoids reduce responses to AMPA receptor activation and blockade in nucleus tractus solitarius.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anti-Inflammatory Agents; Baroreflex; Corticosterone; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Hormone Antagonists; Male; Microinjections; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Solitary Nucleus | 2003 |
Influence of inhibitory and excitatory inputs on serotonin efflux differs in the dorsal and median raphe nuclei.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Extracellular Space; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Motor Activity; Neural Inhibition; Pyridazines; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Serotonin | 2003 |
Ethanol dual modulatory actions on spontaneous postsynaptic currents in spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Central Nervous System Depressants; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Motor Neurons; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2003 |
Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Laminectomy; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Urethra | 2003 |
Activation of protein kinase C by the error signal from a basal ganglia-forebrain circuit in the zebra finch song control nuclei.
Topics: 2-Amino-5-phosphonovalerate; Animals; Basal Ganglia; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Fura-2; Glutamic Acid; In Vitro Techniques; Male; Medial Forebrain Bundle; Prosencephalon; Protein Kinase C; Signal Transduction; Songbirds; Time Factors; Vocalization, Animal | 2003 |
Glutamate release in the nucleus accumbens is involved in behavioral depression during the PORSOLT swim test.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Male; Microdialysis; Microinjections; Motor Activity; Nucleus Accumbens; Physical Stimulation; Rats; Rats, Sprague-Dawley; Swimming; Tail; Time Factors; Valine | 2003 |
Brain edema induced by in vitro ischemia: causal factors and neuroprotection.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antioxidants; Brain Edema; Cell Hypoxia; Cyclic N-Oxides; Cyclosporine; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; In Vitro Techniques; Male; Mitochondria; Neuroprotective Agents; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, Glutamate; Sodium-Calcium Exchanger; Spin Labels; Water | 2003 |
In vitro reconstitution of signal transmission from a hair cell to the growth cone of a chick vestibular ganglion cell.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Calcium; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Fura-2; Ganglia, Sensory; Glutamic Acid; Growth Cones; Hair Cells, Vestibular; Hippocampus; Immunohistochemistry; In Vitro Techniques; Neural Conduction; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Signal Transduction; Time Factors; Valine; Vestibule, Labyrinth | 2003 |
Evidence for a glutamatergic modulation of the cholinergic function in the human enteric nervous system via NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aged; Colon, Ascending; Colon, Sigmoid; Enteric Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Immunohistochemistry; In Vitro Techniques; Kynurenic Acid; Male; Muscle, Smooth; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate | 2003 |
Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes.
Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cell Line; Cells, Cultured; Coculture Techniques; Cycloleucine; Cytosol; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Epithelial Cells; Glutamic Acid; Green Fluorescent Proteins; Humans; Indomethacin; Luminescent Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Patch-Clamp Techniques; Prostaglandins; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Transfection; Valine; Xanthones | 2003 |
[Effect of adenosine A1 receptor antagonist on learning and memory and analysis of its mechanism].
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Adenosine A1 Receptor Antagonists; Animals; Brain; Female; gamma-Aminobutyric Acid; Glutamic Acid; Learning; Male; Mice; Random Allocation; Scopolamine; Xanthines | 2003 |
Spinal control of erection by glutamate in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Pressure; Catheterization; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Penile Erection; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stimulation, Chemical | 2004 |
Involvement of endogeneous glutamate in the stimulatory effect of norepinephrine and serotonin on the hypothalamo-pituitary-adrenocortical axis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Pituitary-Adrenal System; Quinoxalines; Radioimmunoassay; Rats; Serotonin; Serotonin Receptor Agonists; Valine | 2004 |
Local gamma-aminobutyric acid and glutamate circuit control of hypophyseotrophic corticotropin-releasing factor neuron activity in the paraventricular nucleus of the hypothalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Corticotropin-Releasing Hormone; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Microscopy, Electron; Neurons; Organ Culture Techniques; Paraventricular Hypothalamic Nucleus; Radiometry; Rats; Rats, Sprague-Dawley; Synapses; Valine | 2004 |
A new cytochemical method for ultrastructural localization of Co2+ in rat hippocampal CA1 pyramidal neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Anesthetics, Local; Animals; Cobalt; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Histocytochemistry; In Vitro Techniques; Male; Microscopy, Electron; Pyramidal Cells; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Tetrodotoxin | 2004 |
Involvement of a glutamergic mechanism in gamma-dendrotoxin-induced hippocampal neuronal cell loss in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Elapid Venoms; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Male; Neurons; Peptides; Potassium Channel Blockers; Rats; Rats, Wistar; Seizures | 2004 |
Glutamate release increases during mossy-CA3 LTP but not during Schaffer-CA1 LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartic Acid; Calcium; Colforsin; Coloring Agents; Cyclopropanes; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Magnesium; Male; Mossy Fibers, Hippocampal; Neuroglia; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred Strains; Neuronal Plasticity; Neurons; Presynaptic Terminals; Sulfonamides; Time Factors | 2004 |
On the regulation of NMDA receptors by nitric oxide.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Humans; Hydrazines; In Vitro Techniques; Kidney; Male; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Photolysis; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Transfection; Uric Acid | 2004 |
Synaptic interactions between pyramidal cells and interneurone subtypes during seizure-like activity in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Nerve Net; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Seizures; Synapses | 2004 |
Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration.
Topics: 2-Amino-5-phosphonovalerate; Alzheimer Disease; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kynurenic Acid; Memantine; Microtubule-Associated Proteins; Nerve Degeneration; Neurofibrils; Neuroprotective Agents; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; tau Proteins | 2004 |
Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Central Nervous System Stimulants; Dopamine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synapses; Time Factors; Transferrin; Ventral Tegmental Area | 2004 |
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Optical mapping reveals developmental dynamics of Mg2+-/APV-sensitive components of glossopharyngeal glutamatergic EPSPs in the embryonic chick NTS.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Mapping; Brain Stem; Chick Embryo; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glossopharyngeal Nerve; Glutamic Acid; Magnesium; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 2004 |
Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Bicuculline; Calbindin 2; Calcium; Calcium-Binding Proteins; Cell Count; Cell Size; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Nerve Net; Parvalbumins; Picrotoxin; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Time Factors; Valine | 2004 |
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium | 2004 |
Stimulation of N-methyl-D-aspartate receptors, AMPA receptors or metabotropic glutamate receptors leads to rapid internalization of AMPA receptors in cultured nucleus accumbens neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Immunohistochemistry; Male; Neurons; Nucleus Accumbens; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2004 |
Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rats.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Long-Term Potentiation; N-Methylaspartate; Nervous System Physiological Phenomena; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Valine | 2004 |
Heterosynaptic co-activation of glutamatergic and dopaminergic afferents is required to induce persistent long-term potentiation.
Topics: Animals; Benzazepines; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neurons, Afferent; Rats; Rats, Wistar; Synapses; Time Factors; Valine | 2004 |
Characterisation of the effects of ATPA, a GLU(K5) kainate receptor agonist, on GABAergic synaptic transmission in the CA1 region of rat hippocampal slices.
Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Membrane Potentials; Neural Inhibition; Propionates; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission; Valine | 2004 |
Tracheal tone and the role of ionotropic glutamate receptors in the nucleus ambiguus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dogs; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kynurenic Acid; Male; Medulla Oblongata; Muscle Tonus; Muscle, Smooth; Receptors, Glutamate; Trachea; Xanthurenates | 2004 |
Differentiation of mouse embryonic stem cells into a defined neuronal lineage.
Topics: Animals; Bicuculline; Blotting, Western; Calmodulin-Binding Proteins; Carrier Proteins; Cell Count; Cell Differentiation; Cell Lineage; Cells, Cultured; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; GABA Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Homeodomain Proteins; Immunohistochemistry; Indoles; Intermediate Filament Proteins; Membrane Potentials; Mice; Nerve Tissue Proteins; Nestin; Neuroglia; Neurogranin; Neurons; Paired Box Transcription Factors; Patch-Clamp Techniques; PAX6 Transcription Factor; Quinoxalines; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, AMPA; Receptors, Nerve Growth Factor; Repressor Proteins; Stem Cells; Synaptophysin; Tetrodotoxin; Time Factors; Tretinoin; Tubulin; Valine | 2004 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Phenols; Picrotoxin; Piperidines; Protein Subunits; Pyrrolidines; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Bile Acids and Salts; Blood-Brain Barrier; Coloring Agents; Dehydrocholic Acid; Deoxycholic Acid; Electrophysiology; Epilepsies, Partial; Evans Blue; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Permeability; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Serum; Serum Albumin; Somatosensory Cortex | 2004 |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; N-Methylaspartate; Pyrazoles; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thermodynamics; Tritium | 2004 |
The 5-HT receptor antagonist M100,907 prevents extracellular glutamate rising in response to NMDA receptor blockade in the mPFC.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Space; Fluorobenzenes; Glutamic Acid; Male; Microdialysis; Nicotine; Piperazines; Piperidines; Potassium Chloride; Prefrontal Cortex; Rats; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin | 2004 |
Glutamate-associated plasticity in the ventral tegmental area is necessary for conditioning environmental stimuli with morphine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Behavior, Animal; Conditioning, Operant; Cyclic AMP; Drug Interactions; Environment; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Morphine; Narcotics; Neuronal Plasticity; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Thionucleotides; Ventral Tegmental Area | 2004 |
Putative NMDA receptors in Hydra: a biochemical and functional study.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Cell Membrane; Concanavalin A; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Glutathione; Glycine; Hydra; Kynurenic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine | 2004 |
Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Rats; Receptors, N-Methyl-D-Aspartate | 2004 |
The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals.
Topics: Alkanes; Animals; Bicuculline; Bungarotoxins; Chromatography, High Pressure Liquid; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Linoleic Acid; Lysine; Male; Maleimides; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Receptors, Presynaptic; Synaptic Transmission; Valine | 2005 |
Time-dependent involvement of the dorsal hippocampus in trace fear conditioning in mice.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amygdala; Animals; Conditioning, Psychological; Cues; Excitatory Amino Acid Antagonists; Fear; Glutamic Acid; Hippocampus; Learning; Male; Memory; Mice; Mice, Inbred C57BL; Neural Pathways; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors | 2005 |
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Calcium; Cell Death; Cells, Cultured; Culture Media, Conditioned; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; Kynurenic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schwann Cells; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Autonomic Fibers, Preganglionic; Axonal Transport; Bicuculline; Chlorides; Electric Stimulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Herpesvirus 1, Suid; Homeostasis; In Situ Hybridization; Interneurons; Isoenzymes; Kynurenic Acid; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Spinal Cord; Strychnine | 2005 |
The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Blotting, Western; Brain; Calcium; Cell Line; Cell Size; Cloning, Molecular; Dendritic Spines; DNA-Binding Proteins; Drug Interactions; Egtazic Acid; Ephrin-B1; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Humans; Immunohistochemistry; Immunoprecipitation; Microscopy, Immunoelectron; Models, Neurological; Neoplasm Proteins; Neurons; p21-Activated Kinases; Protein Serine-Threonine Kinases; Proteins; rac1 GTP-Binding Protein; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Antisense; RNA, Small Interfering; Synaptosomes; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Tetrodotoxin; Time Factors; Transcription Factors; Transfection; Valine | 2005 |
NMDA receptor stimulation in the absence of extracellular Ca2+ potentiates Ca2+ influx-dependent cell death system.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Drug Synergism; Extracellular Fluid; Female; Glutamic Acid; Neurons; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2005 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescence Resonance Energy Transfer; Gene Expression; Glutamic Acid; Glycine; Hippocampus; Humans; Insecta; Luminescent Proteins; Microscopy, Confocal; Molecular Biology; Mutagenesis, Site-Directed; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Quinoxalines; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors; Transfection | 2005 |
Interaction of GABA and glutamate in the horizontal limb of diagonal band of Broca (hDB): role in cardiovascular responses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Blood Pressure; Diagonal Band of Broca; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Male; Microinjections; Neural Inhibition; Neurons; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate | 2005 |
Noncholinergic excitatory actions of motoneurons in the neonatal mammalian spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Animals, Newborn; Cholinergic Antagonists; Evoked Potentials, Motor; Glutamic Acid; Immunohistochemistry; Locomotion; Mice; Microscopy, Confocal; Motor Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Spinal Cord | 2005 |
Cortical glutamatergic markers in schizophrenia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; In Situ Hybridization; Kainic Acid; Male; Middle Aged; Postmortem Changes; Radioligand Assay; Receptors, Glutamate; Schizophrenia; Tritium | 2005 |
A noncanonical release of GABA and glutamate modulates neuronal migration.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Bicuculline; Bromodeoxyuridine; Cell Movement; Dideoxynucleosides; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Immunohistochemistry; In Vitro Techniques; Mice; Mice, Mutant Strains; Mice, Transgenic; Microtubule-Associated Proteins; Munc18 Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2005 |
Gliotoxicity in hippocampal cultures is induced by transportable, but not by nontransportable, glutamate uptake inhibitors.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Death; Cells, Cultured; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Neuroglia; Neurons; Neurotoxins; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Synaptically released and exogenous ACh activates different nicotinic receptors to enhance evoked glutamatergic transmission in the lateral geniculate nucleus.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aconitine; Analysis of Variance; Animals; Bicuculline; Bungarotoxins; Calcium; Calcium Channel Blockers; Chick Embryo; Conotoxins; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Geniculate Bodies; Glutamic Acid; In Vitro Techniques; Magnesium; Membrane Potentials; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Quinoxalines; Receptors, Nicotinic; Synapses; Synaptic Transmission; Time Factors | 2005 |
GABA and glutamate receptors in the horizontal limb of diagonal band of Broca (hDB): effects on cardiovascular regulation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bicuculline; Blood Pressure; Diagonal Band of Broca; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Glutamic Acid; Heart Rate; Male; Microinjections; Muscimol; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate; Time Factors | 2005 |
Electrophysiological properties of human hypothalamic hamartomas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Bicuculline; Cadmium Chloride; Child; Child, Preschool; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Glutamic Acid; Hamartoma; Humans; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Infant; Isoenzymes; Kainic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periodicity; Phosphopyruvate Hydratase; Potassium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Valine | 2005 |
Differential effects of NMDA and AMPA/kainate receptor antagonists on nitric oxide production in rat brain following intrahippocampal injection.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Down-Regulation; Drug Administration Routes; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2005 |
Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Calcium; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Microscopy, Confocal; Neurons; Neurotoxins; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetanus Toxin; Tetrodotoxin; Time Factors | 2005 |
Cooperative glutamatergic and cholinergic mechanisms generate short-term modifications of synaptic effectiveness in prepositus hypoglossi neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Animals; Animals, Newborn; Atropine; Brain Stem; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoglossal Nerve; In Vitro Techniques; Membrane Potentials; Muscarinic Antagonists; Nerve Net; Neurons; Patch-Clamp Techniques; Pirenzepine; Rats; Synaptic Transmission; Time Factors; Valine | 2005 |
Theta bursts set up glutamatergic as well as GABA-ergic plasticity in neonatal rat hippocampal CA1 neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Theta Rhythm | 2006 |
NMDA receptors in layer 4 spiny stellate cells of the mouse barrel cortex contain the NR2C subunit.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Genes, Reporter; Glutamic Acid; Lac Operon; Lidocaine; Magnesium; Membrane Potentials; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Promoter Regions, Genetic; Protein Subunits; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Somatosensory Cortex; Synapses; Synaptic Transmission; Tetrodotoxin | 2006 |
Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Inhalation; Animals; Calcium; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Isoflurane; Male; Nerve Endings; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin | 2006 |
Plasticity-related regulation of the hippocampal proteome.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbocyanines; Electric Stimulation; Electrophoresis, Gel, Two-Dimensional; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Neuronal Plasticity; Proteome; Synapses | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Dendrites contain a spacing pattern.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cells, Cultured; Cerebellum; Dendrites; Diffusion; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Mice; Microtubule-Associated Proteins; Microtubules; Morphogenesis; Neocortex; Neurons; Nocodazole; Paclitaxel; Potassium Chloride; Pyramidal Cells; Rats; Sodium Channel Blockers; Staining and Labeling; Tetrodotoxin; Valine | 2006 |
Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Substitution; Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hippocampus; Humans; Ionomycin; Kidney; Models, Molecular; Mutation, Missense; N-Methylaspartate; Neuronal Plasticity; Phosphorylation; Point Mutation; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Isoforms; Protein Processing, Post-Translational; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Synapses; Transfection | 2006 |
Respiratory activation of the genioglossus muscle involves both non-NMDA and NMDA glutamate receptors at the hypoglossal motor nucleus in vivo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Hypoglossal Nerve; Male; Medulla Oblongata; Microdialysis; Microinjections; Motor Neurons; Muscle, Skeletal; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; Respiratory Physiological Phenomena; Synaptic Transmission; Tongue; Vagotomy; Vagus Nerve; Vagus Nerve Injuries | 2006 |
NAD(P)H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Brain; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavoproteins; Fluorescence; GABA Antagonists; Glutamic Acid; Glycolysis; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mitochondria; NADP; Neuroglia; Neurons; Pyruvates; Synapses | 2006 |
Estrogen modulates the spinal N-methyl-D-aspartic acid-mediated pelvic nerve-to-urethra reflex plasticity in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Estrogens; Female; Glutamic Acid; N-Methylaspartate; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Urethra | 2006 |
Subthalamic stimulation evokes complex EPSCs in the rat substantia nigra pars reticulata in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Isonicotinic Acids; Neural Pathways; Neurons; Parkinson Disease; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Substantia Nigra; Subthalamic Nucleus; Synaptic Transmission; Time Factors | 2006 |
Interaction between glutamate and GABA systems in the integration of sympathetic outflow by the paraventricular nucleus of the hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2006 |
Effects of selective unilateral dorsal root(s) rhizotomy on micturition reflex in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Dose-Response Relationship, Drug; Electromyography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Injections, Spinal; Muscle Contraction; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Rhizotomy; Spinal Nerve Roots; Urination; Urodynamics | 2006 |
Effects of intertrigeminal region NMDA and non-NMDA receptors on respiratory responses in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Apnea; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Trigeminal Nuclei | 2007 |
Inhibition of nuclear factor kappaB is associated with neuroprotective effects of glycyrrhizic acid on glutamate-induced excitotoxicity in primary neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Blotting, Western; Calcium; Caspase 3; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Female; Glutamic Acid; Glycyrrhizic Acid; Membrane Potentials; Neurons; Neuroprotective Agents; NF-kappa B; Poly(ADP-ribose) Polymerases; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2006 |
Intra-ventral pallidal glutamate antagonists block expression of morphine-induced place preference.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Association Learning; Choice Behavior; Conditioning, Classical; Excitatory Amino Acid Antagonists; Globus Pallidus; Glutamic Acid; Injections; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mental Recall; Morphine; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Opioid, mu; Social Environment | 2006 |
Glutamatergic activity modulates the phase-shifting effects of gastrin-releasing peptide and light.
Topics: 2-Amino-5-phosphonovalerate; Animals; Circadian Rhythm; Cricetinae; Dicarboxylic Acids; Drug Interactions; Excitatory Amino Acid Antagonists; Gastrin-Releasing Peptide; Glutamic Acid; Light; Male; Mesocricetus; Neurotransmitter Uptake Inhibitors; Photic Stimulation; Pyrrolidines; Suprachiasmatic Nucleus; Third Ventricle | 2006 |
Reelin signaling facilitates maturation of CA1 glutamatergic synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Matrix Proteins; Gene Expression Regulation, Developmental; Glutamic Acid; Hippocampus; Humans; Mice; Mice, Transgenic; Nerve Tissue Proteins; Pyramidal Cells; Reelin Protein; Serine Endopeptidases; Signal Transduction; Synapses; Transfection | 2007 |
Synaptic activation of dendritic AMPA and NMDA receptors generates transient high-frequency firing in substantia nigra dopamine neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Dopamine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses; Tyrosine 3-Monooxygenase | 2007 |
Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Heart Rate; Hypertension; Kynurenic Acid; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Vasomotor System | 2007 |
Neurosteroids alter glutamate-induced changes in neurite morphology of NG108-15 cells.
Topics: 2-Amino-5-phosphonovalerate; Cell Adhesion; Cell Line, Tumor; Excitatory Amino Acid Agonists; Glioma; Glutamic Acid; Humans; Hybrid Cells; Neurites; Neuroblastoma; Piperidines; Pregnenolone; Receptors, N-Methyl-D-Aspartate; Steroids | 2007 |
When administered into the nucleus accumbens core or shell, the NMDA receptor antagonist AP-5 reinstates cocaine-seeking behavior in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence | 2007 |
Methamphetamine exposure antagonizes N-methyl-D-aspartate receptor-mediated neurotoxicity in organotypic hippocampal slice cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Binding, Competitive; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Male; Methamphetamine; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2007 |
Out of the cleft: the source and target of extra-synaptic glutamate in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Patch-Clamp Techniques; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Tissue Distribution | 2007 |
Endogenous GABA and glutamate finely tune the bursting of olfactory bulb external tufted cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Isonicotinic Acids; Male; Neurons; Olfactory Bulb; Pyridazines; Rats; Rats, Sprague-Dawley; Valine | 2007 |
D-Serine inhibits AMPA receptor-mediated current in rat hippocampal neurons.
Topics: Action Potentials; Amino Acids; Aminobutyrates; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Molecular Structure; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Valine | 2007 |
The impact of chronic network hyperexcitability on developing glutamatergic synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Blotting, Western; Child; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Humans; Immunohistochemistry; Nerve Net; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Membranes; Tetrodotoxin | 2007 |
Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex.
Topics: 2-Amino-5-phosphonovalerate; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Patch-Clamp Techniques; Phenylcarbamates; Phenytoin; Propylene Glycols; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 2007 |
Role for NMDA receptors in visceral nociceptive transmission in the anterior cingulate cortex of viscerally hypersensitive rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anaphylaxis; Animals; Cerebral Cortex; Colonic Diseases; Disease Models, Animal; Egg Hypersensitivity; Egg Proteins; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hyperalgesia; Male; Microdialysis; Neuronal Plasticity; Pain Measurement; Pain Threshold; Pressure; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2008 |
NMDA receptor blocker ameliorates ischemia-reperfusion-induced renal dysfunction in rat kidneys.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kidney Cortex; Kidney Diseases; Kidney Medulla; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury | 2008 |
Critical differences in magnitude and duration of N-methyl D-aspartate(NMDA) receptor activation between long-term potentiation (LTP) and long-term depression (LTD) induction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2008 |
Endocannabinoids mediate neuron-astrocyte communication.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Calcium; Cannabinoid Receptor Modulators; Cell Communication; Egtazic Acid; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Photolysis; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Type C Phospholipases; Valine | 2008 |
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine | 2008 |
Neuroadaptive changes in the mesocortical glutamatergic system during chronic nicotine self-administration and after extinction in rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electrochemistry; Excitatory Amino Acid Agents; Extinction, Psychological; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nicotine; Nicotinic Agonists; Potassium Chloride; Prefrontal Cortex; Rats; Rats, Inbred Lew; Self Administration; Ventral Tegmental Area | 2008 |
Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microscopy, Electron, Scanning; N-Methylaspartate; Potassium Chloride; Pregnenolone; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium; Valine | 2008 |
Impact of protein kinase C activation on epileptiform activity in the hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Benzoates; Benzophenanthridines; Enzyme Activation; Epilepsy; Glutamic Acid; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Picrotoxin; Protein Kinase C; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Signal Transduction | 2008 |
Functional interrelations between nucleus raphé dorsalis and nucleus raphé medianus: a dual probe microdialysis study of glutamate-stimulated serotonin release.
Topics: 2-Amino-5-phosphonovalerate; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Glutamic Acid; Male; Mesencephalon; Microdialysis; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Time Factors | 2009 |
Stimulation of NMDA and AMPA glutamate receptors elicits distinct concentration dynamics of nitric oxide in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2009 |
Abnormal network activity in a targeted genetic model of human double cortex.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroporation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Humans; In Vitro Techniques; Malformations of Cortical Development; Membrane Potentials; Microtubule-Associated Proteins; Mutation; Nerve Net; Neurons; Neuropeptides; Pregnancy; Quinoxalines; Rats; Rats, Wistar; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways.
Topics: Animals; Arginine; Cannabinoid Receptor Modulators; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Dronabinol; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucocorticoids; Glutamic Acid; GTP-Binding Proteins; Guanosine Diphosphate; Hypothalamus; In Vitro Techniques; Male; Neurons; Nitric Oxide; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Piperidines; Pyrans; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Rimonabant; Signal Transduction; Synapses; Synaptic Transmission; Thionucleotides; Valine | 2009 |
Post-training infusion of glutamate into the bed nucleus of the stria terminalis enhanced inhibitory avoidance memory: an effect involving norepinephrine.
Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memory; Motor Activity; Norepinephrine; Propranolol; Rats; Rats, Wistar; Septal Nuclei; Valine | 2009 |
Presynaptic muscarinic receptors enhance glutamate release at the mitral/tufted to granule cell dendrodendritic synapse in the rat main olfactory bulb.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Animals, Newborn; Biophysics; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Models, Biological; Muscarinic Antagonists; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Pirenzepine; Presynaptic Terminals; Rats; Receptors, Muscarinic; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
NMDA receptor activation by spontaneous glutamatergic neurotransmission.
Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Miniature Postsynaptic Potentials; Neocortex; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2009 |
Depolarization-induced release of endocannabinoids by murine dorsal motor nucleus of the vagus nerve neurons differentially regulates inhibitory and excitatory neurotransmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arachidonic Acids; Benzoxazines; Brain Stem; Calcium Signaling; Cannabinoid Receptor Modulators; Capsaicin; Efferent Pathways; Endocannabinoids; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Inhibitory Postsynaptic Potentials; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; Morpholines; Naphthalenes; Neurons; Piperidines; Pyrazoles; Pyridazines; Receptor, Cannabinoid, CB1; Receptors, Presynaptic; Rimonabant; Tetrodotoxin; Vagus Nerve | 2009 |
Vesicular glutamate filling and AMPA receptor occupancy at the calyx of Held synapse of immature rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Benzothiadiazines; Brain Stem; Excitatory Postsynaptic Potentials; Glutamic Acid; Kynurenic Acid; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Vesicles; Temperature; Tetrodotoxin | 2009 |
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Movement; Cerebral Cortex; Electroporation; Embryo, Mammalian; Female; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Homeodomain Proteins; Interneurons; K Cl- Cotransporters; LIM-Homeodomain Proteins; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microtubule-Associated Proteins; Models, Biological; Muscimol; Nerve Tissue Proteins; Nifedipine; omega-Conotoxin GVIA; Organ Culture Techniques; Pregnancy; Quinoxalines; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sequence Deletion; Symporters; Transcription Factors; Valine | 2009 |
Synaptic and extrasynaptic factors governing glutamatergic retinal waves.
Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Aspartic Acid; Calcium; Dihydro-beta-Erythroidine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; N-Methylaspartate; Neural Inhibition; Nicotinic Antagonists; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2009 |
Reduced expression of the "fast" calcium transporter PMCA2a during homeostatic plasticity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Down-Regulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Homeostasis; Neuronal Plasticity; Plasma Membrane Calcium-Transporting ATPases; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synapses | 2009 |
Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patterns.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Lidocaine; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Time Factors; Tubulin; Valine | 2009 |
Electrophysiology and pharmacology of the optic input to the rat intergeniculate leaflet in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Circadian Rhythm; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Geniculate Bodies; Glutamic Acid; In Vitro Techniques; Male; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Visual Pathways | 2009 |
Functional effects of somatostatin receptor 1 activation on synaptic transmission in the mouse hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amides; Analysis of Variance; Animals; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Receptors, Somatostatin; Somatostatin; Synaptic Transmission | 2009 |
Taste memory trace disruption by AP5 administration in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Association Learning; Avoidance Learning; Conditioning, Classical; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamic Acid; Inhibition, Psychological; Male; Memory; Memory Disorders; Neuropsychological Tests; Rats; Rats, Wistar; Synaptic Transmission; Taste Perception | 2010 |
Sensitization of rat facial cutaneous mechanoreceptors by activation of peripheral N-methyl-d-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Estrogens; Excitatory Amino Acid Antagonists; Face; Female; Glutamic Acid; Male; Mechanoreceptors; Physical Stimulation; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sensory Thresholds; Sex Characteristics; Skin Physiological Phenomena; Trigeminal Ganglion | 2010 |
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds | 2010 |
Substance P and glutamate receptor antagonists improve the anti-arthritic actions of dexamethasone in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dexamethasone; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Glutamic Acid; Injections, Intra-Articular; Isoindoles; Knee Joint; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P; Time Factors | 2010 |
Off-line concomitant release of dopamine and glutamate involvement in taste memory consolidation.
Topics: Amygdala; Animals; Avoidance Learning; Benzazepines; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Dopamine; Electrophoresis, Capillary; Glutamic Acid; Male; Memory; Microdialysis; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Taste; Valine | 2010 |
Effects and mechanisms of L-glutamate microinjected into nucleus ambiguus on gastric motility in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Gastrointestinal Motility; Glutamic Acid; Male; Medulla Oblongata; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Vagotomy | 2010 |
Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synaptic Transmission | 2010 |
Reduced effect of NMDA glutamate receptor antagonist on ethanol-induced ataxia and striatal glutamate levels in mice lacking ENT1.
Topics: 2-Amino-5-phosphonovalerate; Animals; Ataxia; Corpus Striatum; Equilibrative Nucleoside Transporter 1; Ethanol; Glutamic Acid; Male; Mice; Mice, Knockout; Receptors, N-Methyl-D-Aspartate | 2010 |
Metaplasticity at single glutamatergic synapses.
Topics: Anesthetics, Local; Animals; Biophysics; Dendritic Spines; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Long-Term Potentiation; Models, Biological; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetanus Toxin; Tetrodotoxin; Time Factors; Transfection; Valine | 2010 |
Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Biological Clocks; Brain Stem; Cadmium Chloride; Dihydro-beta-Erythroidine; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Glycyrrhetinic Acid; Humans; In Vitro Techniques; Larva; Models, Biological; Movement; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Periodicity; Pyridazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming; Xenopus | 2010 |
The effects of DL-AP5 and glutamate on ghrelin-induced feeding behavior in 3-h food-deprived broiler cockerels.
Topics: 2-Amino-5-phosphonovalerate; Animals; Chickens; Feeding Behavior; Food Deprivation; Ghrelin; Glutamates; Glutamic Acid; Infusions, Intraventricular; Receptors, N-Methyl-D-Aspartate | 2011 |
Network oscillations in rod-degenerated mouse retinas.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Age Factors; Animals; Carbenoxolone; Cyclooxygenase Inhibitors; Disease Models, Animal; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glutamic Acid; Glycine; In Vitro Techniques; Light; Male; Meclofenamic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Net; Neural Inhibition; Periodicity; Pyridazines; Quinoxalines; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Sodium Channel Blockers; Statistics as Topic; Tetrodotoxin | 2011 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Preconditioning effects of tumor necrosis factor-α and glutamate on calcium dynamics in rat organotypic hippocampal cultures.
Topics: Animals; Animals, Newborn; Calcium; Cell Death; Cell Survival; Drug Administration Schedule; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Imidazoles; Male; Nonlinear Dynamics; Organ Culture Techniques; Propidium; Pyridines; Rats; Rats, Wistar; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Valine | 2011 |
Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Estrogen Replacement Therapy; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Models, Animal; N-Methylaspartate; Neurotransmitter Agents; Ovariectomy; Pregnanolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Glutamatergic pre-ictal discharges emerge at the transition to seizure in human epilepsy.
Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Biophysics; Brain Mapping; Confidence Intervals; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Magnesium; Male; Middle Aged; Nerve Net; Potassium Chloride; Quinoxalines; Valine; Young Adult | 2011 |
Use-dependent AMPA receptor block reveals segregation of spontaneous and evoked glutamatergic neurotransmission.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Lidocaine; Male; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Polyamines; Receptors, AMPA; Tetrodotoxin; Valine | 2011 |
Type 1 equilibrative nucleoside transporter regulates ethanol drinking through accumbal N-methyl-D-aspartate receptor signaling.
Topics: 2-Amino-5-phosphonovalerate; Alcohol Drinking; Analysis of Variance; Animals; Blotting, Western; Cyclic AMP Response Element-Binding Protein; Equilibrative Nucleoside Transporter 1; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Knockout; Microdialysis; Nucleus Accumbens; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Self Administration; Signal Transduction | 2011 |
Effects of NMDA receptor modulators on a blood-brain barrier in vitro model.
Topics: 2-Amino-5-phosphonovalerate; Blood-Brain Barrier; Blotting, Western; Calcium; Cell Line; Dizocilpine Maleate; Endothelial Cells; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; In Vitro Techniques; Membrane Proteins; Occludin; Phosphoproteins; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Zonula Occludens-1 Protein | 2011 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine | 2012 |
Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Hippocampus; In Vitro Techniques; Inhalation Exposure; Interleukin-1alpha; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroglia; Neurons; Particulate Matter; Rats; Receptors, AMPA; RNA, Messenger; Tumor Necrosis Factor-alpha; Vehicle Emissions | 2011 |
GABA(B) restrains release from singly-evoked GABA terminals.
Topics: Analysis of Variance; Animals; Benzylamines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Phosphinic Acids; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Sodium Channel Blockers; Solitary Nucleus; Synapses; Tetrodotoxin; Valine | 2011 |
Carisbamate (RWJ-333369) inhibits glutamate transmission in the granule cell of the dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Biophysics; Calcium Channel Blockers; Carbamates; Dentate Gyrus; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Male; Neurons; omega-Conotoxin GVIA; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Synaptic Transmission | 2011 |
Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche.
Topics: Action Potentials; Animals; Animals, Newborn; Bacterial Proteins; Biophysical Phenomena; Cell Adhesion Molecules, Neuronal; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Matrix Proteins; GABA Antagonists; Glutamic Acid; Green Fluorescent Proteins; Interneurons; Iontophoresis; Luminescent Proteins; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Neurogenesis; Neuropeptide Y; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Picrotoxin; Pro-Opiomelanocortin; Quinoxalines; Reelin Protein; Serine Endopeptidases; Stem Cell Niche; Synaptic Potentials; Time Factors; Valine | 2011 |
Two free radical pathways mediate chemical hypoxia-induced glutamate release in synaptosomes from the prefrontal cortex.
Topics: Adenosine Triphosphate; Animals; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Free Radicals; Glutamic Acid; Hydrogen Peroxide; Hypoxia; Lipid Peroxidation; Male; Mitochondrial Proton-Translocating ATPases; Oxidants; Prefrontal Cortex; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Cyanide; Synaptosomes; Valine | 2012 |
Median preoptic nucleus and subfornical organ drive renal sympathetic nerve activity via a glutamatergic mechanism within the paraventricular nucleus.
Topics: 2-Amino-5-phosphonovalerate; Angiotensin II Type 1 Receptor Blockers; Animals; Bicuculline; Blood Pressure; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Heart Rate; Kidney; Losartan; Male; N-Methylaspartate; Neurons; Paraventricular Hypothalamic Nucleus; Preoptic Area; Rats; Rats, Sprague-Dawley; Subfornical Organ; Sympathetic Nervous System | 2012 |
Dopamine-glutamate interplay in the ventral striatum modulates spatial learning in a receptor subtype-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzazepines; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Habituation, Psychophysiologic; Learning; Male; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, Dopamine; Space Perception; Sulpiride | 2012 |
Sex difference in stress-induced enhancement of hippocampal CA1 long-term depression during puberty.
Topics: Adrenalectomy; Androgens; Animals; Animals, Newborn; Aspartic Acid; CA1 Region, Hippocampal; Corticosterone; Dexamethasone; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucocorticoids; Glutamic Acid; In Vitro Techniques; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Ovariectomy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sex Characteristics; Statistics, Nonparametric; Stress, Psychological; Synaptosomes; Testosterone; Valine | 2012 |
Regulation of neuronal input transformations by tunable dendritic inhibition.
Topics: Animals; Biophysics; Cerebral Cortex; Channelrhodopsins; Dependovirus; DNA-Binding Proteins; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; In Vitro Techniques; Interneurons; Ligand-Gated Ion Channels; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Mutation; Neural Inhibition; Parvalbumins; Patch-Clamp Techniques; Photic Stimulation; Pyramidal Cells; Pyridazines; Receptors, Glycine; RNA, Small Interfering; Synapses; Synaptic Transmission; Transcription Factors; Transduction, Genetic; Valine | 2012 |
Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoxazoles; Cocaine; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide; Self Administration; Signal Transduction; Urea; Ventral Tegmental Area | 2013 |
Astrocyte signaling controls spike timing-dependent depression at neocortical synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Astrocytes; Benzoxazines; Biophysics; Calcium; Calcium Channel Blockers; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Long-Term Synaptic Depression; Morpholines; Naphthalenes; Neocortex; Patch-Clamp Techniques; Piperidines; Probability; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Signal Transduction; Sodium Channel Blockers; Synapses; Tetrodotoxin; Thalamus; Time Factors | 2012 |
Post-acquisition release of glutamate and norepinephrine in the amygdala is involved in taste-aversion memory consolidation.
Topics: Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Animals; Area Under Curve; Avoidance Learning; Conditioning, Classical; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium Chloride; Male; Memory; Microdialysis; Norepinephrine; Propranolol; Rats; Rats, Wistar; Saccharin; Taste; Valine | 2012 |
Triheteromeric N-methyl-D-aspartate receptors differentiate synaptic inputs onto pyramidal neurons in somatosensory cortex: involvement of the GluN3A subunit.
Topics: 2-Amino-5-phosphonovalerate; Algorithms; Animals; Calcium; Electric Stimulation; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; Ion Exchange; Kinetics; Magnesium; Neural Pathways; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synapses | 2012 |
Regulation of acetylcholinesterase activity by nitric oxide in rat neuromuscular junction via N-methyl-D-aspartate receptor activation.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Glutamic Acid; Male; Miniature Postsynaptic Potentials; Neuromuscular Junction; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraoxon; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Valine | 2013 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
Involvement of NMDA receptors in nicotine-mediated central control of hypotensive effects.
Topics: Animals; Blood Pressure; Bradycardia; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypotension; Male; Nicotine; Nicotinic Agonists; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Solitary Nucleus; Valine | 2012 |
Cocaine facilitates glutamatergic transmission and activates lateral habenular neurons.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium Channels; Cocaine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABAergic Neurons; Glutamic Acid; Habenula; Male; Miniature Postsynaptic Potentials; Piperazines; Quinoxalines; Quinpirole; Raclopride; Rats; Receptors, Dopamine; Receptors, Glutamate; Sodium Channels; Synaptic Transmission | 2013 |
ATP induces NO production in hippocampal neurons by P2X(7) receptor activation independent of glutamate signaling.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; In Vitro Techniques; Memory; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P2X7; Rosaniline Dyes; Signal Transduction | 2013 |
Glucocorticoid receptors in the prefrontal cortex regulate dopamine efflux to stress via descending glutamatergic feedback to the ventral tegmental area.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Area Under Curve; Aza Compounds; Chromatography, High Pressure Liquid; Dopamine; Efferent Pathways; Excitatory Amino Acid Antagonists; Glutamic Acid; Heterocyclic Compounds, 4 or More Rings; Hormone Antagonists; Male; Microdialysis; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological; Tail; Valine; Ventral Tegmental Area | 2013 |
Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA.
Topics: Animals; Bacterial Proteins; Channelrhodopsins; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hypothalamus; In Vitro Techniques; Light; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Pathways; Neurotensin; Pyrazoles; Quinolines; Quinoxalines; Receptors, Neurotensin; Reward; Self Stimulation; Signal Transduction; Tyrosine 3-Monooxygenase; Valine; Ventral Tegmental Area | 2013 |
Potassium channels control the interaction between active dendritic integration compartments in layer 5 cortical pyramidal neurons.
Topics: Alkaloids; Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Signaling; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Indoles; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Potassium Channels; Probability; Pyramidal Cells; Quinolines; Rats; Rats, Wistar; Somatosensory Cortex; Time Factors; Valine | 2013 |
Cholinergic modulation of primary afferent glutamatergic transmission in rat medullary dorsal horn neurons.
Topics: Acetylcholine; Anesthetics, Local; Animals; Animals, Newborn; Cholinergic Agents; Drug Interactions; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Medulla Oblongata; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Synaptic Transmission; Tetrodotoxin; Valine | 2013 |
Effect of VGLUT inhibitors on glutamatergic synaptic transmission in the rodent hippocampus and prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; CA1 Region, Hippocampal; Dentate Gyrus; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Prefrontal Cortex; Quinoxalines; Synaptic Transmission | 2014 |
Glutamate dysregulation in the trigeminal ganglion: a novel mechanism for peripheral sensitization of the craniofacial region.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthetics, Local; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Mice; Muscle, Skeletal; Neural Conduction; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Time Factors; Trigeminal Ganglion | 2014 |
Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Dopaminergic Neurons; Electrochemistry; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Microinjections; N-Methylaspartate; Nicotine; Nicotinic Agonists; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Self Administration; Ventral Tegmental Area | 2014 |
Copper chelation and exogenous copper affect circadian clock phase resetting in the suprachiasmatic nucleus in vitro.
Topics: Animals; Carbazoles; Chelating Agents; Circadian Clocks; Copper; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Indole Alkaloids; Male; Mice; Mice, Inbred C57BL; Molybdenum; Phenanthrolines; Quinoxalines; Suprachiasmatic Nucleus; Valine | 2014 |
NMDA receptor activation antagonizes the NMDA antagonist-induced antianxiety effect in the elevated plus-maze test in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Male; Maze Learning; Mice; N-Methylaspartate; Quinolones; Receptors, N-Methyl-D-Aspartate; Serine | 2013 |
N-methyl-D-aspartate receptors amplify activation and aggregation of human platelets.
Topics: 2-Amino-5-phosphonovalerate; Blood Platelets; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Male; Memantine; P-Selectin; Platelet Activation; Platelet Aggregation; Receptors, N-Methyl-D-Aspartate | 2014 |
Involvement of the nucleus accumbens shell glutamatergic system in ACPA-induced impairment of inhibitory avoidance memory consolidation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acids; Avoidance Learning; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Memory; Memory Disorders; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Piperidines; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2014 |
Electrophysiological characterization of methyleugenol: a novel agonist of GABA(A) receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Eugenol; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; GABA Agents; GABA-A Receptor Agonists; Glutamic Acid; Glycine; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Valine | 2014 |
A hybrid electrical/chemical circuit in the spinal cord generates a transient embryonic motor behavior.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Genetically Modified; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Nonmammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Green Fluorescent Proteins; Motor Activity; Motor Neurons; Nerve Net; Neural Pathways; Rhombencephalon; Spinal Cord; Synapses; Transcription Factors; Valine; Zebrafish; Zebrafish Proteins | 2014 |
A mechanistic study on urine retention in d-amphetamine addicts.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Amidines; Amphetamine-Related Disorders; Animals; Benzophenanthridines; Central Nervous System Stimulants; Chronic Disease; Colforsin; Dextroamphetamine; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Isoquinolines; N-Methylaspartate; Oxidants; Protein Kinase Inhibitors; Rats, Wistar; Reflex; Spinal Cord; Sulfonamides; Urinary Retention; Urination; Valine | 2014 |
Differential involvement of amygdala and cortical NMDA receptors activation upon encoding in odor fear memory.
Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Basolateral Nuclear Complex; Catheters, Indwelling; Electroshock; Excitatory Amino Acid Antagonists; Fear; Glutamic Acid; Male; Memory; Odorants; Olfactory Cortex; Olfactory Perception; Physical Stimulation; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2014 |
Amygdalar neuronal activity mediates the cardiovascular responses evoked from the dorsolateral periaqueductal gray in conscious rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Arterial Pressure; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; Glutamic Acid; Heart Rate; Male; Microinjections; Muscimol; N-Methylaspartate; Neurons; Periaqueductal Gray; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate | 2015 |
PAR1-activated astrocytes in the nucleus of the solitary tract stimulate adjacent neurons via NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Astrocytes; Calcium; Citrates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Miniature Postsynaptic Potentials; Neurons, Afferent; Peptide Fragments; Rats; Rats, Long-Evans; Receptor, PAR-1; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vagus Nerve | 2015 |
Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Valine; Ventral Tegmental Area | 2015 |
Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Dendritic Spines; Dizocilpine Maleate; Egtazic Acid; Glutamic Acid; GTP-Binding Proteins; Hippocampus; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Valine | 2015 |
The mesencephalic locomotor region sends a bilateral glutamatergic drive to hindbrain reticulospinal neurons in a tetrapod.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain Stem; Calcium; Cell Count; Choline O-Acetyltransferase; Dextrans; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Functional Laterality; Glutamic Acid; In Vitro Techniques; Locomotion; Male; Neurons, Afferent; Urodela; Valine | 2016 |
Involvement of spinal glutamate in nociceptive behavior induced by intrathecal administration of hemokinin-1 in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dizocilpine Maleate; Glutamic Acid; Injections, Spinal; Male; Mice; Nociception; Pain; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tachykinins | 2016 |
TRH modulates glutamatergic synaptic inputs on CA1 neurons of the mouse hippocampus in a biphasic manner.
Topics: 2-Amino-5-phosphonovalerate; Animals; CA1 Region, Hippocampal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Mice; Mice, Inbred C57BL; Neurons; Organ Culture Techniques; Receptors, N-Methyl-D-Aspartate; Thyrotropin-Releasing Hormone | 2016 |
Stimulation of the hypothalamic arcuate nucleus increases brown adipose tissue nerve activity via hypothalamic paraventricular and dorsomedial nuclei.
Topics: 2-Amino-5-phosphonovalerate; Adipose Tissue, Brown; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA-A Receptor Agonists; Glutamic Acid; Immunohistochemistry; Male; Microinjections; Muscimol; N-Methylaspartate; Neural Inhibition; Paraventricular Hypothalamic Nucleus; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Stilbamidines; Sympathetic Nervous System; Temperature; Thermogenesis; Vesicular Glutamate Transport Proteins | 2016 |
Memory trace reactivation and behavioral response during retrieval are differentially modulated by amygdalar glutamate receptors activity: interaction between amygdala and insular cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Analysis of Variance; Animals; Avoidance Learning; Cerebral Cortex; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mental Recall; Neural Pathways; Norepinephrine; Rats; Rats, Wistar; Receptors, Glutamate; Taste; Valine | 2017 |
Blockade of glutamatergic transmission in the primate basolateral amygdala suppresses active behavior without altering social interaction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Basolateral Nuclear Complex; Behavior, Animal; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Interpersonal Relations; Macaca nemestrina; Male; Motor Activity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Social Behavior; Synaptic Transmission | 2017 |
Control of Glutamate Transport by Extracellular Potassium: Basis for a Negative Feedback on Synaptic Transmission.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Cerebral Cortex; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA-A Receptor Antagonists; Glutamic Acid; HEK293 Cells; Humans; Membrane Potentials; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Potassium; Synaptic Transmission; Xanthenes | 2017 |
A Hypothalamic Leptin-Glutamate Interaction in the Regulation of Sympathetic Nerve Activity.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; Gene Knockdown Techniques; Glutamic Acid; Heart Rate; Hypothalamus; Kidney; Leptin; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sympathetic Nervous System; Valine | 2017 |
Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Cells, Cultured; DNA Methylation; Epigenesis, Genetic; Epilepsy; Excitatory Amino Acid Agents; Gene Expression; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Models, Biological; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Valine | 2017 |
Kainate receptor mediated presynaptic LTP in agranular insular cortex contributes to fear and anxiety in mice.
Topics: Animals; Anxiety; Cerebral Cortex; Conditioning, Classical; Disease Models, Animal; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agents; Exploratory Behavior; Fear; Glutamic Acid; Long-Term Potentiation; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Receptors, Kainic Acid; Synaptosomal-Associated Protein 25; Valine | 2018 |
The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Learning; Long-Term Potentiation; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Peptide Fragments; Protein Domains; Quinoxalines; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2018 |
Circuit-selective properties of glutamatergic inputs to the rat prelimbic cortex and their alterations in neuropathic pain.
Topics: Action Potentials; Animals; Animals, Newborn; Channelrhodopsins; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Hippocampus; Male; Nerve Net; Neural Inhibition; Neural Pathways; Neuralgia; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine | 2018 |
Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Apomorphine; Arginine; Capsaicin; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Exploratory Behavior; Glutamic Acid; Male; Microinjections; Nitric Oxide; Nitroprusside; Rats; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Swimming | 2019 |
Electrical stimulation mPFC affects morphine addiction by changing glutamate concentration in the ventral tegmental area.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Morphine; Morphine Dependence; Narcotics; Prefrontal Cortex; Rats; Rats, Wistar; Valine; Ventral Tegmental Area | 2019 |
Glutamate, d-(-)-2-Amino-5-Phosphonopentanoic Acid, and
Topics: 2-Amino-5-phosphonovalerate; Animals; Buffers; Cells, Cultured; Chronic Pain; Glutamic Acid; Humans; Mice; N-Methylaspartate; Neurons; Oocytes; Patch-Clamp Techniques; Primary Cell Culture; Rats; Receptors, Glycine; Recombinant Proteins; Reproducibility of Results; Spinal Cord; Synapses; Synaptic Transmission; Xenopus laevis; Zinc | 2020 |