2-amino-5-phosphonovalerate has been researched along with cocaine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (34.48) | 18.2507 |
| 2000's | 9 (31.03) | 29.6817 |
| 2010's | 10 (34.48) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koob, GF; Maldonado-Lopez, R; Pulvirenti, L | 1 |
| Koob, GF; Pulvirenti, L; Swerdlow, NR | 1 |
| Bradberry, CW; Pap, A | 1 |
| Bolinao, ML; Moghaddam, B | 1 |
| Berrier, R; Koob, GF; Kreifeldt, M; Pulvirenti, L | 1 |
| Elliott, P; Wallis, DI | 1 |
| Edwards, MA; Kantak, KM; O'Connor, TP | 1 |
| Bäckström, P; Hyytiä, P; Liljequist, S | 1 |
| Cornish, JL; Duffy, P; Kalivas, PW | 1 |
| Schmidt, WJ; Tzschentke, TM | 1 |
| Itzhak, Y; Martin, JL | 1 |
| Grimm, JW; Kruzich, PJ; See, RE | 1 |
| Aston-Jones, G; Harris, GC | 1 |
| Abella-Ramírez, C; Alvarez Carillo, JE; Bernardo Colón, A; Burgos-Mártir, MA; del Campo, YE; Maldonado-Vlaar, CS; Rodríguez-Borrero, E | 1 |
| Bäckström, P; Hyytiä, P | 1 |
| Famous, KR; Pierce, RC; Schmidt, HD | 1 |
| Luu, P; Malenka, RC | 1 |
| Argilli, E; Bonci, A; England, PM; Malenka, RC; Sibley, DR | 1 |
| Heshmati, M | 1 |
| He, YY; Li, FQ; Li, YQ; Lu, L; Sacktor, TC; Shaham, Y; Xu, CM; Xue, LF; Xue, YX | 1 |
| Ion, DI; Lammel, S; Malenka, RC; Roeper, J | 1 |
| Aston-Jones, G; Mahler, SV; Smith, RJ | 1 |
| Liu, QS; Liu, X; Nazari, M; Wang, W; Yu, F; Zhong, P | 1 |
| Ator, R; Cruz, FC; Golden, SA; Hoffman, AF; Hope, BT; Koya, E; Lupica, CR | 1 |
| Chen, L; Wang, L; Ye, JH; Zuo, W | 1 |
| Cui, R; Dong, Y; Huang, YH; Ishikawa, M; Lee, BR; Liu, L; Neumann, PA; Otaka, M; Schlüter, OM | 1 |
| Gordon, J; Taylor, JR; Torregrossa, MM | 1 |
| Addy, NA; Behrens, S; Mason, GF; Solecki, W; Wang, J; Wickham, RJ; Zwerling, B | 1 |
| Lüscher, C; Pascoli, V; Terrier, J | 1 |
29 other study(ies) available for 2-amino-5-phosphonovalerate and cocaine
| Article | Year |
|---|---|
NMDA receptors in the nucleus accumbens modulate intravenous cocaine but not heroin self-administration in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Dopamine; Glutamates; Glutamic Acid; Heroin; Male; Microinjections; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration | 1992 |
Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Caffeine; Cocaine; Dopamine; Glutamates; Glutamic Acid; Heroin; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cocaine; Dizocilpine Maleate; Dopamine; Drug Interactions; Excitatory Amino Acids; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
Glutamatergic antagonists attenuate ability of dopamine uptake blockers to increase extracellular levels of dopamine: implications for tonic influence of glutamate on dopamine release.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Chloral Hydrate; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Microdialysis; Nomifensine; Rats | 1994 |
Modulation of locomotor activity by NMDA receptors in the nucleus accumbens core and shell regions of the rat.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Binding, Competitive; Cocaine; Immunohistochemistry; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1994 |
Glutamatergic and non-glutamatergic responses evoked in neonatal rat lumbar motoneurons on stimulation of the lateroventral spinal cord surface.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Citalopram; Cocaine; Desipramine; Electric Stimulation; Ergolines; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketanserin; Membrane Potentials; Motor Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Serotonin Antagonists; Spinal Cord; Strychnine; Synapses | 1993 |
Modulation of the discriminative stimulus and rate-altering effects of cocaine by competitive and noncompetitive N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Cocaine; Discrimination Learning; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Magnesium Chloride; Male; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 1998 |
Site-specific NMDA receptor antagonists produce differential effects on cocaine self-administration in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration | 1999 |
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamates; Glutamic Acid; Male; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 1999 |
Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Choice Behavior; Cocaine; Conditioning, Operant; Excitatory Amino Acid Antagonists; Functional Laterality; Male; Morphine; Motor Activity; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward; Stereotyped Behavior; Time Factors | 1999 |
Cocaine-induced kindling is associated with elevated NMDA receptor binding in discrete mouse brain regions.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Brain; Cocaine; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; Kindling, Neurologic; Male; Mice; Motor Activity; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors; Tritium | 2000 |
Dopamine, but not glutamate, receptor blockade in the basolateral amygdala attenuates conditioned reward in a rat model of relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Behavior, Addictive; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Motor Activity; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Recurrence; Reward; Self Administration | 2001 |
Critical role for ventral tegmental glutamate in preference for a cocaine-conditioned environment.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cocaine; Cocaine-Related Disorders; Cues; Environment; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 2003 |
NMDA antagonist AP-5 increase environmentally induced cocaine-conditioned locomotion within the nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Cocaine; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Locomotion; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2006 |
Involvement of AMPA/kainate, NMDA, and mGlu5 receptors in the nucleus accumbens core in cue-induced reinstatement of cocaine seeking in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Motor Activity; Nucleus Accumbens; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Self Administration | 2007 |
When administered into the nucleus accumbens core or shell, the NMDA receptor antagonist AP-5 reinstates cocaine-seeking behavior in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence | 2007 |
Spike timing-dependent long-term potentiation in ventral tegmental area dopamine cells requires PKC.
Topics: Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Phorbol Esters; Protein Kinase C; Time Factors; Valine; Ventral Tegmental Area | 2008 |
Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cycloheximide; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D5; Time Factors; Ventral Tegmental Area | 2008 |
Cocaine-induced LTP in the ventral tegmental area: new insights into mechanism and time course illuminate the cellular substrates of addiction.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Long-Term Potentiation; Receptors, Dopamine D5; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine; Ventral Tegmental Area | 2009 |
Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Male; Memory; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Oligopeptides; Organophosphonates; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome; Time Factors; Valine | 2011 |
Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Bicuculline; Biotin; Cerebral Cortex; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Patch-Clamp Techniques; Reward; Substantia Nigra; Synapses; Tyrosine 3-Monooxygenase | 2011 |
Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoxazoles; Cocaine; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide; Self Administration; Signal Transduction; Urea; Ventral Tegmental Area | 2013 |
Phosphodiesterase 4 inhibition impairs cocaine-induced inhibitory synaptic plasticity and conditioned place preference.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cocaine; Conditioning, Operant; CREB-Binding Protein; Cyclic Nucleotide Phosphodiesterases, Type 4; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Microinjections; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrosine 3-Monooxygenase; Valine; Ventral Tegmental Area | 2012 |
Silent synapses in selectively activated nucleus accumbens neurons following cocaine sensitization.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthetics, Local; Animals; Biophysics; Cocaine; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Synapses; Tetrodotoxin; Time Factors | 2012 |
Cocaine facilitates glutamatergic transmission and activates lateral habenular neurons.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium Channels; Cocaine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABAergic Neurons; Glutamic Acid; Habenula; Male; Miniature Postsynaptic Potentials; Piperazines; Quinoxalines; Quinpirole; Raclopride; Rats; Receptors, Dopamine; Receptors, Glutamate; Sodium Channels; Synaptic Transmission | 2013 |
Exposure to cocaine regulates inhibitory synaptic transmission in the nucleus accumbens.
Topics: Anesthetics, Local; Animals; Cocaine; Conditioning, Operant; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Self Administration; Synapses; Tetrodotoxin; Time Factors; Valine | 2013 |
Double dissociation between the anterior cingulate cortex and nucleus accumbens core in encoding the context versus the content of pavlovian cocaine cue extinction.
Topics: Analysis of Variance; Animals; Baclofen; Cocaine; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; GABA-A Receptor Agonists; Gyrus Cinguli; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Valine | 2013 |
Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking.
Topics: Acetylcholine; Anesthetics, Local; Animals; Benzazepines; Cholinergic Antagonists; Cocaine; Cues; Dopamine; Dopamine Agonists; Drug-Seeking Behavior; Lidocaine; Male; Mecamylamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine; Time Factors; Valine; Ventral Tegmental Area | 2013 |
Cell-Type Specific Insertion of GluA2-Lacking AMPARs with Cocaine Exposure Leading to Sensitization, Cue-Induced Seeking, and Incubation of Craving.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Neurons; Receptors, AMPA; Receptors, Dopamine; Transduction, Genetic; Vasoconstrictor Agents | 2016 |