2-amino-5-phosphonovalerate and cgp 39551

2-amino-5-phosphonovalerate has been researched along with cgp 39551 in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	57 (81.43)	18.2507
2000's	9 (12.86)	29.6817
2010's	4 (5.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kretschmer, BD; Schmidt, WJ; Volz, L; Volz, TL; Zadow, B	1
Baudry, M; Maren, S; Thompson, RF	1
Bradford, HF; Cotterell, KL; Croucher, MJ	2
Bischoff, C; Tiedtke, PI	1
Barnabei, O; Contestabile, A; Migani, P; Virgili, M	1
Bubser, M; Keseberg, U; Notz, PK; Schmidt, WJ	1
Hönack, D; Löscher, W	1
Liljequist, S	1
Fassbender, CP; Hönack, D; Löscher, W	1
Asikainen, A; Freund, TF; Gulyas, A; Lahtinen, H; Partanen, J; Riekkinen, P; Sirviö, J; Ylinen, A	1
Baud, J; Baumann, P; Bittiger, H; Fagg, GE; Olpe, HR; Portet, C; Pozza, MF; Schmutz, M; Steinmann, M; Thedinga, K	1
Brugger, F; Fagg, GE; Olpe, HR; Pozza, MF	1
Allgeier, H; Fagg, GE; Heckendorn, R; Jeker, A; Klebs, K; Olpe, HR; Portet, C; Schmutz, M; van Riezen, H; Vassout, A	1
Allgeier, H; Angst, C; Bittiger, H; Brundish, D; Fagg, GE; Heckendorn, R; Olpe, HR; Pozza, MF; Schmutz, M; van Riezen, H	1
Fagg, GE; Massieu, L; McVey, M; Thedinga, KH	1
Mennini, T; Miari, A; Presti, ML; Rizzi, M; Samanin, R; Vezzani, A	1
Little, HJ; Rabbani, M; Wright, EJ	1
Ammendola, D; De Sarro, A; De Sarro, G; Nava, F	1
Hartikainen, T; Koivisto, E; Pitkänen, M; Riekkinen, PJ; Sirviö, J; Sivenius, J; Ylinen, A	1
Barnabei, O; Contestabile, A; Virgili, M	1
Little, HJ; Ripley, TL	2
Millan, MJ; Seguin, L	1
Contestabile, A; Facchinetti, F; Virgili, M	1
Ciani, E; Contestabile, A; Facchinetti, F; Virgili, M	1
Contestabile, A; Dall'Olio, R; Facchinetti, F; Gandolfi, O	1
Jessa, M; Nazar, M; Palejko, W; Plaznik, A	1
Halsey, MJ; Henley, M; Maclean, CJ; Meldrum, BS; Pearce, PC; Pearson, J; Ward, EM	1
Hyvönen, M; Lahtinen, H; Miettinen, R; Riekkinen, PJ; Sirviö, J; Ylinen, A	1
Annies, R; Hönack, D; Löscher, W	1
Hönack, D; Löscher, W; Rundfeldt, C	1
Czechowska, G; Czuczwar, SJ; Dziki, M; Kleinrok, Z; Pietrasiewicz, T; Turski, WA	2
De Witte, P; Deuceuninck, D; Lamblin, F	1
Butterworth, AR; Little, HJ; Rabbani, M; Wright, J; Zhou, Q	1
Ciani, E; Contestabile, A; Guarnieri, T	1
Ciani, E; Contestabile, A; Dall'Olio, R; Facchinetti, F; Sparapani, M; Virgili, M	1
Fratelli, M; Rizzi, M; Sparvoli, S; Vezzani, A; Zinetti, M	1
Hatipoğlu, I; Koyuncuoğlu, H; Sarica, O	1
Ciani, E; Contestabile, A; Facchinetti, F; Sparapani, M; Virgili, M	1
Ciani, E; Contestabile, A; Dall'Olio, R; Facchinetti, F; Fonnum, F; Virgili, M	1
Maj, J; Rogóz, Z; Skuza, G	1
Foy, MR; Kim, JJ; Thompson, RF	1
Gall, CM; Guthrie, KM; Sullivan, RM; Wilson, DA	1
Ammendola, D; De Sarro, A; De Sarro, G; Patel, S	1
Mares, P; Vachová, D; Velísek, L	1
Ciani, E; Contestabile, A; Paulsen, RE; Rizzi, S	1
Danysz, W; Frankiewicz, T; Parsons, CG; Zajaczkowski, W	1
Cabello, P; Contreras, E; Germany, A; González, P; Norris, B	1
Ciani, E; Contestabile, A; Dall'Olio, R; Gandolfi, O; Sparapani, M	1
Dunworth, SJ; Stephens, DN	1
Contestabile, A; Dall'Olio, R; Facchinetti, F; Gandolfi, O; Lucchi, R; Sparapani, M; Tregnago, M; Virgili, M	1
D'Hooge, R; De Deyn, PP; Hiramatsu, M; Mori, A; Raes, A; Van Bogaert, PP	1
D'Hooge, R; De Deyn, PP; Raes, A; Van Bogaert, PP; Van de Vijver, G	1
Bäckström, P; Hyytiä, P; Liljequist, S	1
Danysz, W; Karcz-Kubicha, M; Wedzony, K; Zajaczkowski, W	1
Contestabile, A; Monti, B	1
Marcus, MM; Mathé, JM; Nomikos, GG; Svensson, TH	1
Dunworth, SJ; Ripley, TL; Stephens, DN	1
Contestabile, A; Marri, L; Monti, B	1
Cebere, A; Cebers, G; Kosowski, AR; Liljequist, S; Swanhagen, AC	1
Grillner, P; Jardemark, K; Mameli-Engvall, M; Rawal, N; Schilström, B; Svensson, TH	1
Kosowski, AR; Liljequist, S	1
Delgado-García, JM; Gruart, A; Muñoz, MD	1
Ivanov, VB; Schilström, B; Svensson, TH; Wiker, C	1
Bevins, RA; Murray, JE; Polewan, RJ; Walker, AW	1
Czuczwar, M; Kiś, J; Nieoczym, D; Rejdak, K; Turski, WA; Wlaź, P	1
Al-Mohanna, FA; Andres, B; Collison, KS; Inglis, A; Mata, P; Shibin, S; Thiam, J; Ubungen, R	1
Al-Mohanna, FA; Andres, B; Collison, KS; Inglis, A; Mata, P; Saleh, S; Shibin, S; Thiam, J; Ubungen, R	1

Reviews

1 review(s) available for 2-amino-5-phosphonovalerate and cgp 39551

Article	Year
CGP 37849 and CGP 39551: novel competitive N-methyl-D-aspartate receptor antagonists with potent oral anticonvulsant activity. Progress in clinical and biological research, 1990, Volume: 361 Topics: 2-Amino-5-phosphonovalerate; Administration, Oral; Animals; Anticonvulsants; Binding, Competitive; Kinetics; Rats; Receptors, N-Methyl-D-Aspartate	1990

Other Studies

69 other study(ies) available for 2-amino-5-phosphonovalerate and cgp 39551

Article	Year
The contribution of the different binding sites of the N-methyl-D-aspartate (NMDA) receptor to the expression of behavior. Journal of neural transmission. General section, 1992, Volume: 87, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Catalepsy; Cycloserine; Dizocilpine Maleate; Haloperidol; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1992
Effects of the novel NMDA receptor antagonist, CGP 39551, on field potentials and the induction and expression of LTP in the dentate gyrus in vivo. Synapse (New York, N.Y.), 1992, Volume: 11, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electrophysiology; Evoked Potentials; Hippocampus; Male; Neuronal Plasticity; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1992
Weak anticonvulsant activity of CGP 37849 and CGP 39551 against kindled seizures following systemic administration. European journal of pharmacology, 1992, Apr-22, Volume: 214, Issue:2-3 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Injections, Intraperitoneal; Injections, Intravenous; Kindling, Neurologic; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Seizures	1992
Competitive and non-competitive NMDA receptor antagonists in spatial learning tasks. European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dizocilpine Maleate; Learning; Male; Memory; Motor Activity; Orientation; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1992
Competitive NMDA receptor antagonists raise electrically kindled generalized seizure thresholds. Neurochemical research, 1992, Volume: 17, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anticonvulsants; Binding, Competitive; Electric Stimulation; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Seizures	1992
Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers. Neuropharmacology, 1992, Volume: 31, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Epilepsy; Kainic Acid; Male; Neuroglia; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Syndrome	1992
Differential behavioural and neurochemical effects of competitive and non-competitive NMDA receptor antagonists in rats. European journal of pharmacology, 1992, Dec-08, Volume: 229, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dopamine; Male; Memantine; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1992
Anticonvulsant and behavioral effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Ataxia; Behavior, Animal; Carbamazepine; Dizocilpine Maleate; Female; Kindling, Neurologic; Motor Activity; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
The competitive NMDA receptor antagonist, CGP 39551, inhibits ethanol withdrawal seizures. European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Diet; Dizocilpine Maleate; Ethanol; Hippocampus; Mice; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome	1991
Regional alterations in brain amino acids after administration of the N-methyl-D-aspartate receptor antagonists MK-801 and CGP 39551 in rats. Neuroscience letters, 1991, Mar-11, Volume: 124, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Brain Chemistry; Brain Mapping; Dizocilpine Maleate; Female; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Behavioural, electrophysiological and histopathological changes following sustained stimulation of the perforant pathway input to the hippocampus: effect of the NMDA receptor antagonist, CGP 39551. Brain research, 1991, Jul-12, Volume: 553, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Electroencephalography; Hippocampus; Learning; Male; Memory; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activity. British journal of pharmacology, 1990, Volume: 99, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Binding, Competitive; Electrophysiology; Electroshock; Glutamates; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine	1990
Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551. European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Electrophysiology; Hippocampus; Iontophoresis; Male; Oxadiazoles; Piperazines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Substantia Nigra; Valine	1990
The competitive NMDA receptor antagonists CGP 37849 and CGP 39551 are potent, orally-active anticonvulsants in rodents. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Electroshock; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Postural Balance; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
A comparative analysis of the neuroprotective properties of competitive and uncompetitive N-methyl-D-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy. Neuroscience, 1993, Volume: 55, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biomarkers; Cell Death; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Drug Administration Schedule; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections; Injections, Intraperitoneal; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Pipecolic Acids; Piperazines; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate	1993
Adaptive changes in the NMDA receptor complex in rat hippocampus after chronic treatment with CGP 39551. European journal of pharmacology, 1994, Dec-12, Volume: 271, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Kynurenic Acid; Male; Norepinephrine; Phencyclidine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1994
Tolerance to competitive NMDA antagonists, but no crosstolerance with barbiturates. Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Ataxia; Behavior, Animal; Dizocilpine Maleate; Drug Tolerance; Hypnotics and Sedatives; Male; Mice; Motor Activity; N-Methylaspartate; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome	1995
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice. Brain research, 1995, Feb-06, Volume: 671, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures	1995
The effects of NMDA receptor antagonists at anticonvulsive doses on the performance of rats in the water maze task. European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3 Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Binding, Competitive; Dizocilpine Maleate; Electroshock; Learning; Male; Memory; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Swimming	1995
Simultaneous blockade of non-NMDA ionotropic receptors and NMDA receptor-associated ionophore partially protects hippocampal slices from protein synthesis impairment due to simulated ischemia. Hippocampus, 1995, Volume: 5, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glucose; Hippocampus; In Vitro Techniques; Ionophores; Leucine; Male; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	1995
Effects on ethanol withdrawal hyperexcitability of chronic treatment with a competitive N-methyl-D-aspartate receptor antagonist. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Drug Administration Schedule; Ethanol; Handling, Psychological; Male; Mice; Mice, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome; Time Factors	1995
Chemically-diverse ligands at the glycine B site coupled to N-methyl-D-aspartate (NMDA) receptors selectively block the late phase of formalin-induced pain in mice. Neuroscience letters, 1994, Aug-29, Volume: 178, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Acetates; Acetic Acid; Animals; Anticonvulsants; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Formaldehyde; Indoles; Ligands; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain; Propionates; Pyrrolidinones; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1994
Chronic neonatal NMDA blockade results in long-term cholinergic increase in the rat spinal cord. Neuroreport, 1994, Oct-27, Volume: 5, Issue:16 Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Analysis of Variance; Animals; Animals, Newborn; Biomarkers; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors	1994
Decreased excitotoxic sensitivity in the olfactory cortex of adult rats after neonatal NMDA blockade. Neuroreport, 1994, Oct-27, Volume: 5, Issue:16 Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Animals, Newborn; Enzyme Induction; Hippocampus; Kainic Acid; Nerve Degeneration; Olfactory Bulb; Ornithine Decarboxylase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1994
Chronic neonatal blockade of N-methyl-D-aspartate receptor by CGP 39551 increases dopaminergic function in adult rat. Neuroscience, 1994, Volume: 63, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agonists; Ergolines; Motor Activity; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Spiperone; Stereotyped Behavior; Time Factors	1994
Effects of antagonists at the NMDA receptor complex in two models of anxiety. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Behavior, Animal; Conflict, Psychological; Diazepam; Dizocilpine Maleate; Drinking; Electroshock; Exploratory Behavior; Injections, Intraventricular; Kynurenic Acid; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1994
The orally active NMDA receptor antagonist CGP 39551 ameliorates the high pressure neurological syndrome in Papio anubis. Brain research, 1993, Sep-17, Volume: 622, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Administration, Oral; Animals; Anticonvulsants; Electroencephalography; Female; High Pressure Neurological Syndrome; Male; Papio; Receptors, N-Methyl-D-Aspartate; Seizures; Tremor	1993
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats. Brain research, 1993, Oct-15, Volume: 625, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Learning; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatostatin; Space Perception	1993
Comparison of competitive and uncompetitive NMDA receptor antagonists with regard to monoaminergic neuronal activity and behavioural effects in rats. European journal of pharmacology, 1993, Oct-05, Volume: 242, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Biogenic Monoamines; Brain; Dizocilpine Maleate; Female; Motor Activity; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior	1993
Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy. The European journal of neuroscience, 1993, Nov-01, Volume: 5, Issue:11 Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epilepsies, Partial; Female; Kindling, Neurologic; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior	1993
Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics. European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Carbamazepine; Drug Synergism; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Seizures	1993
Modulation of alcohol preference by NMDA antagonists in male rats. Alcohol and alcoholism (Oxford, Oxfordshire), 1993, Volume: 28, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain; Capillary Permeability; Choice Behavior; Ethanol; Magnesium; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome	1993
Possible involvement of NMDA receptor-mediated transmission in barbiturate physical dependence. British journal of pharmacology, 1994, Volume: 111, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Barbital; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Hippocampus; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome	1994
Fos protein induction, neuropathology, and pharmacological protection after excitotoxic brain insult. Experimental brain research, 1994, Volume: 98, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Injections; Kainic Acid; Male; N-Methylaspartate; Neurotoxins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Time Factors	1994
Long-lasting effects of chronic neonatal blockade of N-methyl-D-aspartate receptor through the competitive antagonist CGP 39551 in rats. Neuroscience, 1994, Volume: 60, Issue:2 Topics: 2-Amino-5-phosphonovalerate; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Aging; Animals; Animals, Newborn; Aspartic Acid; Benzamides; Benzazepines; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Motor Activity; Nutrition Disorders; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate	1994
Changes in the ADP-ribosylation status of some hippocampal proteins are linked to kindling progression. Neuroreport, 1994, Jun-02, Volume: 5, Issue:10 Topics: 2-Amino-5-phosphonovalerate; Adenosine Diphosphate Ribose; Animals; Arginine; Autoradiography; Electrophoresis, Polyacrylamide Gel; Hemoglobins; Hippocampus; Injections, Intraventricular; Kindling, Neurologic; Male; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P2	1994
Morphine physical dependence intensification by hypoglycemia: NMDA receptor involvement. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain; Dizocilpine Maleate; Hypoglycemia; Insulin; Male; Morphine Dependence; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome	1994
Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine decarboxylase. Neurochemistry international, 1994, Volume: 24, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Cerebral Cortex; Enzyme Induction; Hippocampus; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reference Values; Spermidine; Spermine; Telencephalon	1994
Competitive antagonists of NMDA receptors, CGP 37849 and CGP 39551, enhance the anticonvulsant activity of valproate against electroconvulsions in mice. European journal of pharmacology, 1993, Feb-23, Volume: 232, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Receptors, N-Methyl-D-Aspartate; Seizures; Valproic Acid	1993
Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801. Brain research. Developmental brain research, 1993, Aug-20, Volume: 74, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Choline O-Acetyltransferase; Dizocilpine Maleate; Female; Motor Activity; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1993
Some central effects of CGP 37849 and CGP 39551, the competitive NMDA receptor antagonists: potential antiparkinsonian activity. Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:1 Topics: 2-Amino-5-phosphonovalerate; alpha-Methyltyrosine; Animals; Antiparkinson Agents; Antipsychotic Agents; Biogenic Monoamines; Catalepsy; Central Nervous System Agents; Clonidine; Levodopa; Male; Methyltyrosines; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reserpine; Tyrosine 3-Monooxygenase	1993
Ethanol withdrawal hyperexcitability in vitro is selectively decreased by a competitive NMDA receptor antagonist. Brain research, 1995, Nov-13, Volume: 699, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Time Factors	1995
Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation. Proceedings of the National Academy of Sciences of the United States of America, 1996, May-14, Volume: 93, Issue:10 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Infant, Newborn; Learning; Long-Term Potentiation; Male; Memory; Neuronal Plasticity; Rats; Receptors, N-Methyl-D-Aspartate; Stress, Physiological	1996
NMDA-receptor modulation of lateral inhibition and c-fos expression in olfactory bulb. Brain research, 1996, May-06, Volume: 719, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; Ketamine; Male; Neural Inhibition; Olfactory Bulb; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger	1996
Lack of development of tolerance to anticonvulsant effects of two excitatory amino acid antagonists, CGP [corrected] 37849 and CGP 39551 in genetically epilepsy-prone rats. Brain research, 1996, Sep-23, Volume: 734, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Drug Administration Schedule; Drug Tolerance; Epilepsy; Excitatory Amino Acid Antagonists; Genetic Predisposition to Disease; Male; Motor Activity; Rats; Rats, Sprague-Dawley	1996
Excitatory amino acid antagonists and pentylenetetrazol-induced seizures during ontogenesis. IV. Effects of CGP 39551. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Convulsants; Drug Evaluation, Preclinical; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; Male; Pentylenetetrazole; Rats; Rats, Wistar	1997
Chronic pre-explant blockade of the NMDA receptor affects survival of cerebellar granule cells explanted in vitro. Brain research. Developmental brain research, 1997, Mar-17, Volume: 99, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apoptosis; Cell Survival; Cellular Senescence; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Neuroprotective Agents; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1997
Uncompetitive NMDA receptor antagonists attenuate NMDA-induced impairment of passive avoidance learning and LTP. Neuropharmacology, 1997, Volume: 36, Issue:7 Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Long-Term Potentiation; Male; Memantine; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1997
Decrease of tolerance to, and physical dependence on morphine by, glutamate receptor antagonists. European journal of pharmacology, 1997, Aug-13, Volume: 332, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Ketamine; Male; Mice; Morphine; Morphine Dependence; Pain Measurement; Substance Withdrawal Syndrome	1997
Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells. Experimental neurology, 1997, Volume: 148, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Aspartic Acid; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Glutamic Acid; L-Lactate Dehydrogenase; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitroarginine; Piperidines; Putrescine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vitamin E	1997
Sensitisation to repeated withdrawal, in mice treated chronically with diazepam, is blocked by an NMDA receptor antagonist. Psychopharmacology, 1998, Volume: 136, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Convulsants; Diazepam; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission	1998
Neuronal nitric oxide synthase is permanently decreased in the cerebellum of rats subjected to chronic neonatal blockade of N-methyl-D-aspartate receptors. Neuroscience letters, 1998, Dec-11, Volume: 258, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzamides; Body Weight; Cerebellum; Depression, Chemical; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Hyperkinesis; Immunohistochemistry; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Size; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time	1998
Effects of the competitive N-methyl-D-aspartate antagonist CGP 37849 and its ethylester CGP 39551 on N-methyl-D-aspartate-evoked whole-cell currents in cultured spinal neurones and on vestibular stimulation-induced seizures in EL mice. Arzneimittel-Forschung, 1998, Volume: 48, Issue:12 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Avoidance Learning; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Postural Balance; Receptors, N-Methyl-D-Aspartate; Seizures; Spinal Cord; Vestibule, Labyrinth	1998
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones. Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord	1999
Site-specific NMDA receptor antagonists produce differential effects on cocaine self-administration in rats. European journal of pharmacology, 1999, Jul-28, Volume: 378, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration	1999
NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity. Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:11-12 Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Antimetabolites; Antipsychotic Agents; Binding Sites; Cycloleucine; Cycloserine; Disease Models, Animal; Dopamine Agents; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hallucinogens; Locomotion; Male; Phencyclidine; Phthalazines; Protein Structure, Tertiary; Psychotic Disorders; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle	1999
Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum. The European journal of neuroscience, 2000, Volume: 12, Issue:9 Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Caspase 1; Caspase 3; Caspases; Cell Differentiation; Cerebellum; DNA Fragmentation; Excitatory Amino Acid Antagonists; In Situ Nick-End Labeling; Neurons; Ornithine Decarboxylase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2000
Effects of competitive and non-competitive NMDA receptor antagonists on dopamine output in the shell and core subdivisions of the nucleus accumbens. Neuropharmacology, 2001, Volume: 40, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Nucleus Accumbens; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors	2001
Effect of CGP39551 administration on the kindling of ethanol-withdrawal seizures. Psychopharmacology, 2002, Volume: 163, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Alcohol Withdrawal Seizures; Animals; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Motor Activity	2002
NMDA receptor-dependent CREB activation in survival of cerebellar granule cells during in vivo and in vitro development. The European journal of neuroscience, 2002, Volume: 16, Issue:8 Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellar Cortex; Colforsin; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Immunohistochemistry; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	2002
Nicotine-induced dopamine release in the nucleus accumbens is inhibited by the novel AMPA antagonist ZK200775 and the NMDA antagonist CGP39551. Psychopharmacology, 2004, Volume: 175, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dopamine; Male; Microdialysis; Motor Activity; Nicotine; Nucleus Accumbens; Organophosphonates; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Time Factors	2004
Nitric oxide is involved in nicotine-induced burst firing of rat ventral tegmental area dopamine neurons. Neuroscience, 2004, Volume: 125, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Dopamine; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Ganglionic Stimulants; Male; Membrane Potentials; Neurons; NG-Nitroarginine Methyl Ester; Nicotine; Nitric Oxide; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area	2004
The NR2B-selective N-methyl-D-aspartate receptor antagonist Ro 25-6981 [(+/-)-(R,S)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine propanol] potentiates the effect of nicotine on locomotor activity and dopamine release in the nucleus The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Dopamine; Drug Synergism; Male; Microdialysis; Motor Activity; Nicotine; Nucleus Accumbens; Phenols; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2004
Involvement of the CA3-CA1 synapse in the acquisition of associative learning in behaving mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-25, Volume: 26, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amnesia, Anterograde; Amnesia, Retrograde; Animals; Association Learning; Blinking; Conditioning, Classical; Electromyography; Electroshock; Excitatory Postsynaptic Potentials; Extinction, Psychological; Habituation, Psychophysiologic; Hippocampus; Learning Disabilities; Long-Term Potentiation; Male; Mental Recall; Mice; Mice, Inbred C57BL; Pyramidal Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Trigeminal Nerve	2006
Galantamine enhances dopaminergic neurotransmission in vivo via allosteric potentiation of nicotinic acetylcholine receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Analysis of Variance; Animals; Cholinesterase Inhibitors; Donepezil; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Galantamine; Indans; Male; Mecamylamine; Microdialysis; Neurons; Nicotinic Antagonists; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Synaptic Transmission; Ventral Tegmental Area	2007
An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine. Psychopharmacology, 2011, Volume: 213, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Conditioning, Classical; Cyclopentanes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mecamylamine; N-Methylaspartate; Nicotine; Phencyclidine; Phenols; Piperazines; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2011
Orphenadrine-induced convulsive status epilepticus in rats responds to the NMDA antagonist dizocilpine. Pharmacological reports : PR, 2014, Volume: 66, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dizocilpine Maleate; Electroencephalography; Hippocampus; Male; N-Methylaspartate; Orphenadrine; Rats; Rats, Wistar; Seizures; Status Epilepticus	2014
Differential effects of early-life NMDA receptor antagonism on aspartame-impaired insulin tolerance and behavior. Physiology & behavior, 2016, 12-01, Volume: 167 Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartame; Behavior, Animal; Blood Glucose; Dark Adaptation; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Exposure Delayed Effects; Recognition, Psychology; Statistics, Nonparametric; Sweetening Agents	2016
Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression. PloS one, 2018, Volume: 13, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartame; Female; Gene Expression Regulation; Hypothalamo-Hypophyseal System; Male; Mice; Pituitary-Adrenal System; Receptors, N-Methyl-D-Aspartate	2018