2-amino-5-phosphonovalerate has been researched along with 2-amino-7-phosphonoheptanoic acid in 357 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 114 (31.93) | 18.7374 |
| 1990's | 171 (47.90) | 18.2507 |
| 2000's | 48 (13.45) | 29.6817 |
| 2010's | 23 (6.44) | 24.3611 |
| 2020's | 1 (0.28) | 2.80 |
| Authors | Studies |
|---|---|
| Bigge, CF; Drummond, JT; Humblet, C; Johnson, G; Malone, TC; Ortwine, DF; Pinter, GW | 1 |
| Bigge, CF; Brahce, LJ; Coughenour, LL; Drummond, JT; Johnson, G; Marcoux, FW; Ortwine, DF; Probert, AW; Retz, DM | 1 |
| Harrison, BL; McDonald, IA; Weintraub, HJ; Whitten, JP | 1 |
| Baron, BM; McDonald, IA; Miller, F; Muench, D; White, HS; Whitten, JP | 1 |
| Bigge, CF; Bobovski, TP; Brahce, LJ; Coughenour, LL; Drummond, JT; Hays, SJ; Johnson, G; Novak, PM; Rice, MJ | 1 |
| Chittur, S; Griffith, R | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Copenhagen, DR; Dixon, DB | 2 |
| Hansen, AJ; Lauritzen, M | 1 |
| Cook, CJ; Devine, CE; Gilbert, KV; Tavener, A | 1 |
| Hisanaga, K; Sagar, SM; Sharp, FR | 1 |
| Dougherty, PM; Palecek, J; Paleckova, V; Sorkin, LS; Willis, WD | 1 |
| Lu, CL; Shaikh, MB; Siegel, A | 1 |
| Engelsen, BA; Fonnum, F; Furset, K | 1 |
| Pai, KS; Ravindranath, V | 1 |
| De Sarro, A; De Sarro, G; Meldrum, BS; Patel, S | 1 |
| Davies, J; Harris, NC | 1 |
| Champagnat, J; Denavit-Saubié, M; Fortin, G; Velluti, JC | 1 |
| Grigor'ev, VV; Nemanova, VA; Ragulin, VV | 1 |
| Gottesman, J; Miller, RF | 1 |
| Gale, K; Miller, LP; Murray, TF; Zhong, P | 1 |
| Alasuzoff, I; Briggs, RS; Cowburn, RF; Porter, RH; Roberts, PJ | 1 |
| Akaike, N; Himori, N; Imai, M; Matsukura, T; Watanabe, H | 1 |
| Donoso, AO; Gargiulo, PA; Muñoz, V | 1 |
| Conti, L; Ellenberger, SR; Ellenberger, WP; Ferkany, JW; Guzewska, ME; Hudkins, R; Kyle, DJ; Narayanan, BA; Patch, R; Rzeszotarski, WJ | 1 |
| Beninger, RJ; Jhamandas, K; Thanos, PK | 1 |
| Fragoso-Veloz, J; Tapia, R | 1 |
| Benveniste, M; Mayer, ML | 1 |
| Belfiore, P; Berettera, C; Biagetti, R; Magnani, M; Ponzio, F; Pozzi, O | 1 |
| Boje, K; Miller, R; Skolnick, P; Trullas, R; Young, A | 1 |
| Charria Ortiz, GA; Cools, AR; van den Bos, R | 1 |
| Clark, D; Overton, P | 2 |
| Rosenberg, HC; Tietz, EI; Xie, XH | 1 |
| Denavit-Saubie, M; Foutz, AS; Pierrefiche, O; Schmid, K | 1 |
| Bieger, D; Neuman, RS; Wang, YT | 1 |
| Carobrez, AP; De Aguiar, JC; Graeff, FG; Guimarães, FS | 1 |
| Anderton, PJ; Millar, TJ | 1 |
| Dougherty, PM; Willis, WD | 1 |
| Sapru, H; Sundaram, K | 1 |
| Garcia-Munoz, M; Groves, PM; Young, SJ | 1 |
| Halsey, MJ; Meldrum, BS; Millan, MH; Wardley-Smith, B | 3 |
| Glantz, RM; Pfeiffer-Linn, C | 1 |
| Bigalke, H; Lampe, H | 1 |
| Koffler-Smulevitz, D; Nichols, TR | 1 |
| Blanco, C; Cordero, ML; Negrón, AE; Ortiz, JG; Santiago, G | 1 |
| Liu, GQ; Ping, HX; Wu, HQ; Xie, L | 1 |
| Ikonomidou, C; Sieklucka, M; Turski, WA; Urbańska, E | 1 |
| Linn, DM; Massey, SC | 2 |
| Bazil, MK; Gordon, FJ | 4 |
| Clow, DW; Hammer, RP; Lee, SJ | 1 |
| Herting, RL; Nuygen, T; Quartermain, D; Sheu, J | 1 |
| Chai, CY; Kao, MC; Lee, HK; Wang, Y | 1 |
| Lipton, P; Lobner, D | 1 |
| Insel, TR; Skolnick, P; Trullas, R; Winslow, JT | 1 |
| Ohno, Y; Warnick, JE | 1 |
| Bradford, HF; Croucher, MJ | 1 |
| Lanthorn, TH; Watson, GB | 1 |
| Cannon-Spoor, HE; Freed, WJ | 1 |
| Daw, N; Fox, K; Sato, H | 1 |
| Ehrenberger, K; Felix, D | 1 |
| Gobert, A; Guibert, B; Leviel, V | 1 |
| Dürmüller, N; Meldrum, BS; Millan, MH; Wardley-Smith, B | 1 |
| Liu, GQ; Ping, HX; Wu, HQ | 1 |
| Batista-Da-Silva, AP; Carobrez, AP; Rae, GA | 1 |
| Compton, RP; Gaoni, Y; Hood, WF; Lanthorn, TH; Monahan, JB; Rader, RK; Watson, GB | 1 |
| Kumashiro, H; Mori, N; Shimoyamada, K | 1 |
| Massey, SC; Miller, RF | 1 |
| Butler, TW; Butterfield, GC; Chenard, BL; Dominy, BW; Lipinski, CA; Marinovic, LC; Mena, EE; Pagnozzi, M; Ronau, RT; Tsang, T | 1 |
| Crawford, RD; Johnson, DD; Pedder, SC; Tuchek, JM; Wilcox, RI | 1 |
| Carl, GF; Gallagher, BS; Holmes, GL; Hoy, J; McLaughlin, M; Thompson, JL | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Kulovaná, M; Kusá, R; Mares, P; Velísek, L | 1 |
| Coenen, AM; Peeters, BW; van Rijn, CM; Vossen, JM | 1 |
| Skolnick, P; Trullas, R | 1 |
| Baker, RE; Ruijter, JM | 1 |
| Jope, RS; Li, X; Ormandy, GC | 1 |
| Rogers, BC; Tilson, HA | 1 |
| Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ | 1 |
| Copenhagen, DR; Nawy, S; Sie, A | 1 |
| Mori, N; Wada, JA | 1 |
| Buerki, H; Fagg, GE; Mondadori, C; Petschke, F; Weiskrantz, L | 1 |
| Do, KQ; Herrling, PL; Maeder, J; Meier, CL | 1 |
| Lanthorn, TH; Rader, RK; Watson, GB | 1 |
| Castiglioni, M; Samanin, R; Stasi, MA; Vezzani, A; Weckermann, B; Wu, HQ | 1 |
| Romijn, HJ | 1 |
| Bartkowski, H; Roman, R; Simon, R | 1 |
| Champagnat, J; Denavit-Saubié, M; Foutz, AS | 1 |
| Arnolde, SM; Nevins, ME | 1 |
| Clow, DW; Jhamandas, K | 1 |
| Matthies, H; Matthies, HK; Reymann, KG; Schulzeck, K | 1 |
| Choi, DW; Goldberg, MP; Monyer, H | 1 |
| Beart, PM; Manallack, DT; Sheehan, KA | 1 |
| Ogita, K; Yoneda, Y | 1 |
| Auer, RN; Jensen, ML | 1 |
| Davidoff, RA; Hackman, JC; Zhang, DX | 1 |
| Ben-Ari, Y; Cherubini, E; Corradetti, R; Gaiarsa, JL | 1 |
| Meldrum, BS; Rostain, JC; Wardley-Smith, B | 1 |
| Samanin, R; Vezzani, A; Wu, HQ | 2 |
| Ben-Ari, Y; Cherubini, E; King, AE | 1 |
| Freed, WJ | 1 |
| McCaslin, PP; Morgan, WW | 3 |
| Evans, MC; Meldrum, BS; Swan, JH | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Wamil, A | 1 |
| Klockgether, T | 1 |
| Moneta, E; Samanin, R; Vezzani, A; Wu, HQ | 1 |
| Meldrum, BS; Millan, MH; Patel, S | 2 |
| Grigor'ev, VV; Ragulin, VV | 1 |
| Lehmann, J; Tsai, C; Wood, PL | 1 |
| De Prins, E; Marrannes, R; Wauquier, A; Willems, R | 1 |
| Jacquet, YF; Squires, RF | 1 |
| Jacquet, YF | 1 |
| Collins, JF; Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Chapman, AG; Cheetham, SC; Hart, GP; Meldrum, BS; Westerberg, E | 1 |
| Cavalheiro, EA; Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA | 1 |
| Carpenter, DO; Ffrench-Mullen, JM; Hori, N | 2 |
| Canning, HM; Leach, MJ; Marden, CM | 1 |
| Beart, PM; Manallack, DT | 1 |
| Stone, TW | 1 |
| Grützner, M; Meldrum, BS; Schneider, C; Stephens, DN; Weidmann, R | 1 |
| Amrick, CL; Bennett, DA | 1 |
| Jhamandas, K; Marien, M | 1 |
| Addae, JI; Stone, TW | 1 |
| Dewhurst, DG | 1 |
| Shinozaki, H | 1 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Connick, JH; Stone, TW | 1 |
| Aitken, PG; Balestrino, M; Somjen, GG | 1 |
| Consolo, S; Forloni, G; Ladinsky, H; Palazzi, E | 1 |
| Lee, M; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Ben-Ari, Y; Cherubini, E; Neuman, R | 1 |
| Kapetanovic, IM; Kupferberg, HJ; Torchin, CD; Yonekawa, WD | 1 |
| Beart, PM; Davies, SN; Jones, MG; Lodge, D; Manallack, DT; Millar, J; Ornstein, PL; Verberne, AJ; Young, N | 1 |
| Choi, DW; Kim, JP | 1 |
| Angelico, P; Samanin, R; Stasi, MA; Vezzani, A; Wu, HQ | 1 |
| Herrling, PL | 1 |
| Wieloch, T | 1 |
| Polc, P | 1 |
| Meldrum, BS; Mello, LM; Millan, MH; Patel, S | 2 |
| Cavalheiro, EA; Meldrum, BS; Turski, L; Turski, WA | 1 |
| Baud, J; Fagg, GE | 1 |
| Ho, PM; Tang, AH | 1 |
| de Sarro, G; Meldrum, B; Millan, M; Patel, S | 1 |
| Cherubini, E; Herrling, PL; Lanfumey, L; Stanzione, P | 1 |
| Balster, RL; Willetts, J | 1 |
| Ross, SM; Seelig, M; Spencer, PS | 1 |
| Ross, SM; Spencer, PS | 1 |
| Bradford, HF; Croucher, MJ; Sunter, DC; Watkins, JC | 1 |
| Chapman, AG; Engelsen, B; Meldrum, BS | 1 |
| Compton, RP; Contreras, PC; Monahan, JB; O'Donohue, TL | 1 |
| Do, KQ; Herrling, PL; Turski, WA | 1 |
| Boast, CA; Pastor, G | 1 |
| Boersma, CA; Faingold, CL; Meldrum, BS; Millan, MH | 2 |
| Compton, RP; Hood, WF; Monahan, JB | 1 |
| Balm, M; Coyle, JT; Markl, A; Zaczek, R | 1 |
| Halsey, MJ; Meldrum, BS; Rostain, JC; Wardley-Smith, B | 1 |
| Gale, K; Piredda, S | 1 |
| Griffiths, T; Meldrum, BS; Simon, RP; Swan, JH | 1 |
| Collins, JF; Curry, K; Perkins, MN; Stone, TW | 1 |
| Collins, JF; Parks, DA; Schwarcz, R | 1 |
| Coyle, JT; Ferkany, JW | 1 |
| Collins, JF; Croucher, MJ; Curry, K; Czuczwar, SJ; Joseph, M; Meldrum, BS; Stone, TW | 1 |
| Bradford, HF; Collins, JF; Peterson, DW | 2 |
| Badman, G; Collins, JF; Croucher, MJ; Meldrum, BS | 1 |
| Coyle, JT; Ferkany, JW; Lehmann, J; Schaefer, P | 1 |
| Croucher, MJ; Jones, AW; Meldrum, BS; Watkins, JC | 1 |
| Halsey, MJ; Meldrum, BS; Wardley-Smith, B | 1 |
| King, AE; Wheal, HV | 1 |
| Cotman, CW; Ganong, AH; Harris, EW | 1 |
| Czuczwar, SJ; Meldrum, B | 1 |
| Aldinio, C; French, ED; Schwarcz, R | 1 |
| Perkins, MN; Stone, TW | 2 |
| Schwarcz, R; Whetsell, WO | 1 |
| Coyle, JT; Ferkany, J; Markl, A; Zaczek, R | 1 |
| Halsey, M; Meldrum, B; Rostain, JC; Wardley-Smit, B | 1 |
| Köhler, C; McBean, GJ; Roberts, PJ; Schwarcz, R; Steiner, HX | 1 |
| Croucher, M; De Sarro, G; Jensen, L; Meldrum, B | 1 |
| De Sarro, G; Meldrum, BS; Reavill, C | 1 |
| Chapman, AG; Meldrum, BS; Westerberg, E | 1 |
| Collins, JF; Perkins, MN; Stone, TW | 1 |
| Chapman, AG; Collins, JF; Meldrum, BS; Westerberg, E | 1 |
| McLennan, H | 1 |
| Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Block, F | 1 |
| Akgören, N; Fabricius, M; Lauritzen, M | 1 |
| Block, F; Schwarz, M | 3 |
| Corsi, C; Fratti, S; Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Gordon, FJ; Kiely, JM | 1 |
| Block, F; Schmitt, T; Schwarz, M | 1 |
| Herrling, PL; Krucker, T; Meier, CL; Salt, TE; Seno, N | 1 |
| Ammendola, D; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Evrard, P; Gadisseux, JF; Gressens, P; Marret, S; Mukendi, R | 1 |
| de Oliveira, CL; Del Bel, EA; Guimarães, FS; Shida, HW; Titze-de-Almeida, R | 1 |
| Lowry, T; Simon, RP; Tanaka, K | 1 |
| Shimosaka, S; Simon, RP; So, YT | 1 |
| Ginski, MJ; Witkin, JM | 1 |
| Folbergrová, J | 2 |
| De Aguiar, JC; Graeff, FG; Guimarães, FS; Russo, AS | 1 |
| Jordan, HH; Sluka, KA; Westlund, KN; Willis, WD | 1 |
| Frohman, LA; Sato, M | 1 |
| Sluka, KA; Westlund, KN | 2 |
| Schubert, K; Shaikh, MB; Siegel, A | 2 |
| Cabrera, RJ; Donoso, AO; Navarro, CE | 1 |
| Garcia-Cairasco, N; Terra, VC | 1 |
| Boulu, RG; Callebert, J; Ghribi, O; Plotkine, M | 1 |
| Gale, K; Halonen, T; Tortorella, A; Zrebeet, H | 1 |
| Hasegawa, T; Kameyama, T; Kinoshita, H; Nabeshima, T; Yamamoto, I | 1 |
| Kinney, GG; Kocsis, B; Vertes, RP | 1 |
| Abe, S; Akazawa, K; Chishaki, A; Goto, Y; Kato, M; Nakamura, M | 1 |
| Corsi, C; Latini, S; Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Faiman, CP; Skolnick, P; Trullas, R; Viu, E | 1 |
| Couratier, P; Dumas, M; Hugon, J; Sindou, P; Vallat, JM | 1 |
| Burgard, EC; Hablitz, JJ | 1 |
| Ebner, TJ; Elias, SA; Yae, H | 1 |
| Ashida, H; Kawakami, Y | 1 |
| Kato, N | 1 |
| Copenhagen, DR; Diamond, JS | 2 |
| Bianchi, L; Giovannini, MG; Michelassi, A; Mutolo, D; Pepeu, G | 1 |
| Hong, M; Jhamandas, K; Milne, B | 1 |
| Baran, H; Du, F; French, ED; McMaster, OG; Schwarcz, R; Wu, HQ | 1 |
| Bagetta, G; De Sarro, GB; Nisticò, G; Spagnolo, C | 1 |
| Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Averill, DB; Tsuchihashi, T | 1 |
| Bradford, HF; Cotterell, KL; Croucher, MJ | 2 |
| Cabrera, RJ; Navarro, CE | 1 |
| Miller, RF; Yu, W | 1 |
| Bodnar, RJ; Cooper, ML; Spinella, M | 1 |
| Morales-Villagrán, A; Tapia, R; Ureña-Guerrero, ME | 1 |
| Yamazaki, M | 1 |
| Couratier, P; Dussartre, C; Hugon, J; Lesort, M; Terro, F | 1 |
| Beninger, RJ; Boegman, RJ; Flesher, S; Jhamandas, KH; Pawley, AC | 1 |
| Graham, SH; Simon, RP; Tanaka, K | 1 |
| Evrard, P; Gressens, P; Marret, S | 1 |
| Chitravanshi, VC; Sapru, HN | 1 |
| Buccafusco, JJ; Feldman, DS | 1 |
| Puig, S; Sorkin, LS | 1 |
| Kawaguchi, K; Simon, RP | 1 |
| Lawand, NB; Westlund, KN; Willis, WD | 1 |
| Car, H; Kuziemka-L eska, M; Wiśniewski, K | 1 |
| Hodge, E; Khandwala, H; Loomis, CW | 1 |
| Artemowicz, B; Lutostańska, A; Wiśniewski, K | 1 |
| Stanojlovic, O; Susic, V; Zivanovic, D | 2 |
| Car, H; Wiśniewski, K | 1 |
| Delius, JD; Gargiulo, PA; Siemann, M | 1 |
| Tang, H; Yamamoto, H | 1 |
| Newman, EA; Zahs, KR | 1 |
| Adamec, RE | 1 |
| Braisted, JC; Chavko, M; Harabin, AL | 1 |
| Khodorov, BI; Koshelev, SG; Sobolevsky, AI | 1 |
| Copenhagen, DR; Hwang, TN; Tian, N | 1 |
| Cazala, P; David, V; Durkin, TP | 1 |
| Jones, DL; Puig, S; Sorkin, LS | 1 |
| Cassidy, RM; Gale, K | 1 |
| Ally, A; Asmundsson, G; Mokler, DJ | 1 |
| Casebeer, D; Faingold, C | 1 |
| Bhatnagar, T; Chitravanshi, VC; Sapru, HN | 1 |
| Faingold, CL; N'Gouemo, P | 1 |
| Bodnar, RJ; Moroz, M; Ragnauth, A; Spinella, M; Znamensky, V | 1 |
| Funes, A; Gargiulo, PA; Landa, AI; Martínez, G; Ropero, C | 1 |
| Dirnagl, U; Isaev, N; Stelmashook, EV; Victorov, I; Weih, M; Zorov, D | 1 |
| Darbin, O; Risso, JJ; Rostain, JC | 1 |
| Folbergrová, J; Haugvicová, R; Mares, P | 1 |
| Aleksandrova, OP; Andreeva, NA; Isaev, NK; Stel'mashuk, EV; Viktorov, IV; Zorov, DB | 1 |
| Ally, A; Chaiyakul, P; Maher, TJ; Reidman, DA | 1 |
| Abraini, JH; Kriem, B; Rostain, JC | 1 |
| Barat, A; Burgos, JS; Ramírez, G | 1 |
| Del Bel, EA; Guimarães, FS; Padovan, CM | 1 |
| Akopian, A; Witkovsky, P | 1 |
| Hefferan, MP; Loomis, CW; Zhang, Z | 1 |
| Alvarado, R; Camacho-Arroyo, I; Manjarrez, J | 1 |
| Faingold, CL; Long, C; Yang, L | 1 |
| Lin, Q; Willis, WD; Zou, X | 1 |
| Jamaluddin, S; Poddar, MK | 1 |
| Hayes, JK; Plachinta, R; Wong, KC; Zhang, Y | 1 |
| Hussain, S; Liptáková, S; Velísková, J | 1 |
| Guimarães, FS; Molchanov, ML | 1 |
| Flores, E; Funes, A; Gargiulo, PA; Landa, AI; Martínez, G; Ropero, C | 1 |
| Gong, QL; Li, P; Peng, YJ; Wang, N | 1 |
| Borelli, KG; Brandão, ML; Nobre, MJ | 1 |
| Laviolette, SR; van der Kooy, D | 1 |
| Faingold, CL; Long, C; Randall, ME; Yang, L | 1 |
| Sitniewska, EM; Wiśniewska, RJ; Wiśniewski, K | 1 |
| Guimarães, FS; Molchanov, ML; Moreira, FA | 1 |
| Guimarães, FS; Padovan, CM | 1 |
| Baviera, M; Calcagno, E; Carli, M; Ceglia, I; Invernizzi, RW; Renoldi, G | 1 |
| Guimarães, FS; Jardim, MC | 1 |
| Faingold, CL; Raisinghani, M | 2 |
| Kaczyńska, K; Szereda-Przestaszewska, M | 1 |
| Mares, P; Slamberová, R | 1 |
| Hivanović, D; Stanojlović, O; Susić, V | 1 |
| Aguiar, DC; Beijamini, V; de Lucca, AC; Guimarães, FS; Moreira, FA | 1 |
| Corrêa, FM; Resstel, LB | 1 |
| Al-Chaer, ED; Lin, C | 1 |
| Beijamini, V; Guimarães, FS | 1 |
| Giorgi, FS; Moshé, SL; Velísek, L; Velísková, J | 1 |
| Montezuma, SR; Rizzo, JF; Shah, HA | 1 |
| Bertoglio, LJ; Guimarães, FS; Zangrossi, H | 1 |
| Bertoglio, LJ; Zangrossi, H | 1 |
| Chrapusta, SJ; Kaczyńska, K; Szereda-Przestaszewska, M | 1 |
| Faingold, CL; Feng, HJ; Yang, L | 1 |
| Gheitasi, IP; Haghparast, A; Lashgari, R | 1 |
| Gustafson, EC; Miller, RF; Stevens, ER; Wolosker, H | 1 |
| Baiardi, G; Beling, A; Borgonovo, J; Gargiulo, PA; Landa, AI; Martínez, G; Ruiz, AM; Sosa, MA | 1 |
| de Menezes, RC; Dimicco, JA; Fontes, MA; Sarkar, S; Zaretsky, DV | 1 |
| Heinmiller, A; Ting-A-Kee, R; van der Kooy, D; Vargas-Perez, H; Yeh, A | 1 |
| Aguiar, DC; Guimarães, FS | 2 |
| Lam, FF; Ng, ES | 1 |
| Brandão, ML; Coimbra, NC; Ferrari, EA; Francisco, A; Maisonnette, SS; Medeiros, P; Mello, RO; Melo, LL; Santos, P | 1 |
| Menzler, J; Zeck, G | 1 |
| Cabrera, R; Giuliani, FA; Laconi, M; Mohn, CE; Rettori, V; Yunes, R | 1 |
| Brüning, CA; Nogueira, CW; Prigol, M; Zeni, G | 1 |
| Druga, R; Folbergrová, J; Otáhal, J | 1 |
| Barbosa-Silva, R; Iacopucci, AP; Mello, RO; Melo-Thomas, L | 1 |
| Aguiar, DC; Fogaça, MV; Gomes, FV; Guimarães, FS; Moreira, FA | 1 |
| Kawabe, K; Kawabe, T; Sapru, HN | 1 |
| Hosseini, N; Nasehi, M; Radahmadi, M; Zarrindast, MR | 1 |
| Biojone, C; Corrêa, FM; Moraes-Neto, TB; Resstel, LB; Scopinho, AA | 1 |
| Bum, EN; Moto, FC; Ngoupaye, GT; Taiwe, GS; Talla, E | 1 |
| Nasehi, M; Oryan, S; Rasekhi, K; Zarrindast, MR | 1 |
| Amin-Yavari, S; Ebrahimi-Ghiri, M; Nasehi, M; Torabi-Nami, M; Zarrindast, MR | 1 |
| Dubach, MF; Dybdal, D; Forcelli, PA; Gale, K; Malkova, L; Wellman, LL | 1 |
| Khakpai, F; Nasehi, M; Zarrindast, MR | 1 |
| Casarotto, PC; Diniz, CR; Joca, SR | 1 |
| Chitravanshi, VC; Kawabe, K; Sapru, HN | 1 |
| Forcelli, PA; Malkova, L; Wellman, LL | 1 |
| Coimbra, NC; Falconi-Sobrinho, LL | 1 |
| Brito, BM; Gobira, PH; Joca, SRL; Sartim, AG | 1 |
| Fernandes, GG; Frias, AT; Pinheiro, LC; Spiacci, A; Tanus-Santos, JE; Zangrossi, H | 1 |
| Mascarenhas, DC; Nunes-de-Souza, RL; Santos-Costa, N; Victoriano, G | 1 |
3 review(s) available for 2-amino-5-phosphonovalerate and 2-amino-7-phosphonoheptanoic acid
| Article | Year |
|---|---|
Pharmacology of the glutamate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Antidepressive Agents; Azepines; Glutamates; Glutamic Acid; Membrane Potentials; Nervous System Diseases; Neurons; Oxazoles; Oxazolidinones; Piperidines; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1988 |
Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Disease Susceptibility; Epilepsy; Glutamates; Glutamine; Limbic System; Microinjections; Pilocarpine; Rats; Rats, Mutant Strains; Seizures | 1988 |
Role of nitric oxide in brain regions related to defensive reactions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Behavior, Animal; Brain; Cats; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escape Reaction; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA Modulators; Imidazoles; Immunohistochemistry; Maze Learning; Midazolam; Models, Biological; NADPH Dehydrogenase; Nitric Oxide; Oxadiazoles; Quinoxalines; Rats | 2005 |
354 other study(ies) available for 2-amino-5-phosphonovalerate and 2-amino-7-phosphonoheptanoic acid
| Article | Year |
|---|---|
Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists.
Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1992 |
Exploration of N-phosphonoalkyl-, N-phosphonoalkenyl-, and N-(phosphonoalkyl)phenyl-spaced alpha-amino acids as competitive N-methyl-D-aspartic acid antagonists.
Topics: Amino Acids; Animals; Binding, Competitive; Brain; Cells, Cultured; Models, Molecular; Molecular Conformation; N-Methylaspartate; Organophosphonates; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1992 |
Modeling of competitive phosphono amino acid NMDA receptor antagonists.
Topics: Binding, Competitive; Computer Simulation; Electricity; Models, Molecular; Organophosphonates; Receptors, N-Methyl-D-Aspartate | 1992 |
(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.
Topics: Animals; Binding, Competitive; Cerebellum; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kindling, Neurologic; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 1990 |
New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; N-Methylaspartate; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes | 1990 |
Multisubstrate analogue inhibitors of glucosamine-6-phosphate synthase from Candida albicans.
Topics: Binding Sites; Candida albicans; Enzyme Inhibitors; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) | 2002 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Suppression of a calcium current by CNQX and kynurenate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Calcium Channel Blockers; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; Ictaluridae; Kynurenic Acid; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina | 1992 |
The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cerebral Cortex; Cortical Spreading Depression; Dizocilpine Maleate; Electrophysiology; Ischemic Attack, Transient; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Contribution of amino acid transmitters to epileptiform activity and reflex suppression in electrically head stunned sheep.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Baclofen; Bicuculline; Blinking; Electric Stimulation; Electrocardiography; Electroencephalography; Epilepsy; Heart Rate; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, GABA-A; Reflex, Pupillary; Sheep; Sheep Diseases; Tiletamine; Zolazepam | 1992 |
N-methyl-D-aspartate antagonists block fos-like protein expression induced via multiple signaling pathways in cultured cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Fetus; Glutamates; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Proto-Oncogene Proteins c-fos; Signal Transduction | 1992 |
The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Capsaicin; Electric Stimulation; Electrophysiology; Female; Hot Temperature; Macaca fascicularis; Neurons; Physical Stimulation; Pregnancy; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Spinal Nerve Roots; Spinothalamic Tracts; Stimulation, Chemical | 1992 |
Role of NMDA receptors in hypothalamic facilitation of feline defensive rage elicited from the midbrain periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Atropine; Cats; Female; Hypothalamus, Middle; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; N-Methylaspartate; Neurotransmitter Agents; Periaqueductal Gray; Quinoxalines; Rage; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1992 |
Two types of glutamate receptors differentially excite amacrine cells in the tiger salamander retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Evoked Potentials, Visual; Photic Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Retina; Urodela | 1992 |
Changes in the levels of glutamate and related amino acids in the intact and decorticated rat neostriatum during various conditions associated with convulsions.
Topics: 2-Amino-5-phosphonovalerate; Acetates; Amino Acids; Animals; Anticonvulsants; Brain Mapping; Caudate Nucleus; Cerebral Cortex; Cerebral Decortication; Corpus Striatum; Electroencephalography; Epilepsy, Tonic-Clonic; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutaminase; Hypoglycemia; Insulin; Male; Methionine Sulfoximine; Penicillin G; Putamen; Rats; Rats, Wistar; Seizures; Synaptic Transmission | 1992 |
Quisqualic acid-induced neurotoxicity is protected by NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ion Channel Gating; L-Lactate Dehydrogenase; Mice; Potassium; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1992 |
Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Epilepsy; Glutamine; Kainic Acid; Limbic System; Male; N-Methylaspartate; Neurotransmitter Agents; Pilocarpine; Pons; Rats; Rats, Wistar; Thalamus | 1992 |
Cortically evoked excitatory synaptic transmission in the cat red nucleus is antagonised by D-AP5 but not by D-AP7.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cats; Electric Stimulation; Neurons; Pipecolic Acids; Piperazines; Receptors, N-Methyl-D-Aspartate; Red Nucleus; Somatosensory Cortex; Synapses; Synaptic Transmission | 1992 |
Responses to repetitive afferent activity of rat solitary complex neurons isolated in brainstem slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Brain Stem; Electric Stimulation; In Vitro Techniques; Medulla Oblongata; Membrane Potentials; Neuronal Plasticity; Neurons, Afferent; Quinoxalines; Rats; Synapses; Synaptic Transmission | 1992 |
[Species differences in the action of concurrent NMDA receptor antagonists in mouse and rat hippocampal neurons].
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Hippocampus; Mice; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Species Specificity | 1992 |
Pharmacological properties of N-methyl-D-aspartate receptors on ganglion cells of an amphibian retina.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Electrodes; In Vitro Techniques; Ion Channels; Kynurenic Acid; Magnesium; Perfusion; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Tetrodotoxin; Zinc | 1992 |
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Amygdala; Animals; Bicuculline; Brain Mapping; Carbachol; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Ibotenic Acid; Kainic Acid; Limbic System; Muscimol; Quisqualic Acid; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
Heterogeneity of NMDA receptors labelled with [3H]3-((+-)-2-carboxypiperazin-4-yl) propyl-1-phosphonic acid ([3H]CPP): receptor status in Alzheimer's disease brains.
Topics: 2-Amino-5-phosphonovalerate; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Animals; Binding Sites; Brain Chemistry; Cerebral Cortex; Humans; In Vitro Techniques; Kinetics; Male; Piperazines; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1992 |
Replenishment of brain adenosine triphosphate content by morphinan-type N-methyl-D-asparatate receptor antagonists, dextrorphan and dextromethorphan through the activation of adenylate kinase.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Adenylate Kinase; Amino Acids; Animals; Brain Chemistry; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Enzyme Activation; Male; Mice; Morphinans; Potassium Cyanide; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Inhibition by N-methyl-D-aspartic acid (NMDA) receptor antagonist of lordosis behavior induced by estrogen followed by progesterone or luteinizing hormone-releasing hormone (LHRH) in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Estradiol; Gonadotropin-Releasing Hormone; Injections, Intraventricular; Male; Neural Inhibition; Progesterone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sexual Behavior, Animal | 1992 |
Pharmacological profile of novel cyclic analogs of 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Electroshock; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship | 1992 |
N-methyl-D-aspartate unilaterally injected into the dorsal striatum of rats produces contralateral circling: antagonism by 2-amino-7-phosphonoheptanoic acid and cis-flupenthixol.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Corpus Striatum; Flupenthixol; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Rotation | 1992 |
NMDA receptor antagonists protect against seizures and wet-dog shakes induced by 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amino Acids; Animals; Behavior, Animal; Male; N-Methylaspartate; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures | 1992 |
Effect of extracellular pH on the potency of N-methyl-D-aspartic acid receptor competitive antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Biphenyl Compounds; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Pipecolic Acids; Propionates; Receptors, N-Methyl-D-Aspartate | 1992 |
Oxiracetam prevents the hippocampal cholinergic hypofunction induced by the NMDA receptor blocker AP7.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Amnesia; Animals; Avoidance Learning; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Pyrrolidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retention, Psychology | 1992 |
Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-D-aspartate receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Learning; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Swimming | 1992 |
Injections of the NMDA-antagonist D-2-amino-7-phosphonoheptanoic acid (AP-7) into the nucleus accumbens of rats enhance switching between cue-directed behaviours in a swimming test procedure.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Attention; Brain Mapping; Cues; Dopamine; Dose-Response Relationship, Drug; Escape Reaction; Injections; Male; Mental Recall; Nucleus Accumbens; Orientation; Problem Solving; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Swimming | 1992 |
Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Corpus Striatum; Dopamine; Electrophysiology; Injections; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1992 |
Anti-pentylenetetrazol effect of intranigral 2-amino-7-phosphonoheptanoate attenuated by muscimol.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Drug Combinations; Male; Muscimol; Pentylenetetrazole; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Substantia Nigra | 1991 |
Endogenous activation of NMDA and non-NMDA glutamate receptors on respiratory neurones in cat medulla.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Decerebrate State; Iontophoresis; Medulla Oblongata; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiratory Center | 1991 |
Activation of NMDA receptors is necessary for fast information transfer at brainstem vagal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Brain Stem; Electric Stimulation; Evoked Potentials, Somatosensory; Histocytochemistry; Male; Medulla Oblongata; Motor Neurons; Neural Pathways; Piperazines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Vagus Nerve | 1991 |
Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal grey.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anti-Anxiety Agents; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Mesencephalon; Microinjections; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Effects of excitatory amino acids and their antagonists on the light response of luminosity and color-opponent horizontal cells in the turtle (Pseudemys scripta elegans) retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Color Perception; Dizocilpine Maleate; Electrophysiology; Kainic Acid; Light; N-Methylaspartate; Photic Stimulation; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Turtles | 1991 |
Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Glutamates; Glutamic Acid; Macaca fascicularis; N-Methylaspartate; Neurons; Quisqualic Acid; Spinothalamic Tracts | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Terminal excitability of the corticostriatal pathway. II. Regulation by glutamate receptor stimulation.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cerebral Cortex; Corpus Striatum; Electrophysiology; Glutamates; Kainic Acid; Male; Nerve Endings; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Brain nuclei and neurotransmitters involved in the regulation of the high pressure neurological syndrome in the rat.
Topics: 2-Amino-5-phosphonovalerate; 2-Chloroadenosine; Acetylcholine; Amino Acids; Animals; Body Temperature; Brain; Carbachol; High Pressure Neurological Syndrome; Male; Mesencephalon; Neurotransmitter Agents; Pons; Rats; Rats, Inbred Strains; Red Nucleus | 1991 |
An arthropod NMDA receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Astacoidea; Cesium; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Immunoenzyme Techniques; Interneurons; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Vision, Ocular | 1991 |
Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Carbamazepine; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Female; Ion Channels; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Phenytoin; Pregnancy; Spinal Cord | 1990 |
Mechanical analysis of heterogenic inhibition between soleus muscle and the pretibial flexors in the cat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Bicuculline; Cats; Electric Stimulation; Electromyography; Female; Hindlimb; Injections, Intravenous; Isometric Contraction; Joints; Male; Muscles; Neural Pathways; Picrotoxin; Proprioception; Reflex; Strychnine | 1991 |
N-methyl-D-aspartate increases the excitability of nigrostriatal dopamine terminals.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Binding, Competitive; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Nerve Fibers; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Inhibition of high-affinity [3H]L-proline binding to rat brain membranes by 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Female; Kinetics; Membranes; Proline; Rats; Rats, Inbred Strains; Tritium | 1991 |
Effect of intrahippocampal quinolinic acid infusion on the amygdala kindling in rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Anticonvulsants; Hippocampus; Injections, Intravenous; Kindling, Neurologic; Male; Neurons; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Aminooxyacetic acid produces excitotoxic lesions in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminooxyacetic Acid; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Corpus Striatum; Female; Glutamate Decarboxylase; Kynurenic Acid; Male; Microinjections; Microscopy, Electron; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Acetylcholine release from the rabbit retina mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Convulsants; Dizocilpine Maleate; Glycine; In Vitro Techniques; Light; Magnesium; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Retina | 1991 |
Spinal NMDA receptors mediate pressor responses evoked from the rostral ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Evoked Potentials; Female; Glutamates; Heart Rate; Medulla Oblongata; Microinjections; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Sympathetic Nervous System | 1991 |
Competitive (AP7) and non-competitive (MK-801) NMDA receptor antagonists differentially alter glucose utilization in rat cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Autoradiography; Binding, Competitive; Carbon Radioisotopes; Cerebral Cortex; Deoxyglucose; Dizocilpine Maleate; Glucose; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1991 |
Milacemide enhances memory storage and alleviates spontaneous forgetting in mice.
Topics: 2-Amino-5-phosphonovalerate; Acetamides; Amino Acids; Animals; Avoidance Learning; Male; Memory; Mice; Monoamine Oxidase Inhibitors; Receptors, N-Methyl-D-Aspartate | 1991 |
Effect of blockade of spinal NMDA receptors on sympathoexcitation and cardiovascular responses produced by cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blood Pressure; Brain Ischemia; Cardiovascular System; Female; Heart Rate; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stereotaxic Techniques; Sympathetic Nervous System; Vagotomy | 1991 |
NMDA antagonists attenuate hypertension induced by carotid clamping in the rostral ventrolateral medulla of rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Arterial Occlusive Diseases; Blood Pressure; Carotid Arteries; Carotid Artery Diseases; Cerebral Ventricles; Hypertension; Injections, Intraventricular; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Pain; Phencyclidine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Vagotomy | 1991 |
Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cyclazocine; Dizocilpine Maleate; Glutamates; Guanidines; Haloperidol; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Ketamine; Kynurenic Acid; Male; Models, Neurological; Phencyclidine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma | 1990 |
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Female; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Social Isolation; Vocalization, Animal | 1990 |
Selective depression of the segmental polysynaptic reflex by phencyclidine and its analogs in the rat in vitro: interaction with N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Binding Sites; Haloperidol; In Vitro Techniques; Magnesium; Male; Methiothepin; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Spinal Cord | 1990 |
NMDA receptor blockade inhibits glutamate-induced kindling of the rat amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Glutamates; Glutamic Acid; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
NMDA receptor antagonists attenuate a portion of the penicillin-induced epileptiform burst.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Epilepsy; Hippocampus; In Vitro Techniques; Male; Penicillins; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
A possible role of AA2 excitatory amino acid receptors in the expression of stimulant drug effects.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Amphetamine; Animals; Apomorphine; Behavior, Animal; Central Nervous System Stimulants; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glutamates; Mice; Motor Activity; Phencyclidine; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Stereotyped Behavior | 1990 |
The effect of varying stimulus intensity on NMDA-receptor activity in cat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Electric Stimulation; Electrodes; Hippocampus; Iontophoresis; Neurons; Photic Stimulation; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Visual Cortex | 1990 |
A microiontophoretic study of the role of excitatory amino acids at the afferent synapses of mammalian inner hair cells.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Male; Neurons, Afferent; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1990 |
The glutamate-mediated release of dopamine in the rat striatum: further characterization of the dual excitatory-inhibitory function.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Caudate Nucleus; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Kinetics; Quinoxalines; Rats; Rats, Inbred Strains; Reference Values; Tetrodotoxin; Tritium; Tyrosine | 1990 |
The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsy; Female; Male; Myoclonus; Nervous System Diseases; Rats; Rats, Inbred Strains; Tremor | 1991 |
Modulation of neuronal activity of locus coeruleus in rats induced by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Electrophysiology; Glutamates; Locus Coeruleus; Male; N-Methylaspartate; Neurons; Quinolinic Acids; Rats; Rats, Inbred Strains | 1990 |
Microinjection of D-2-amino-7-phosphonoheptanoate into the dorsal periaqueductal gray matter reduces the pressor response to glutamate injected at the same site.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamates; Male; Microinjections; Periaqueductal Gray; Rats; Rats, Inbred Strains; Respiration | 1990 |
Cis-2,4-methanoglutamate is a potent and selective N-methyl-D-aspartate receptor agonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Binding, Competitive; Electric Stimulation; Electrophysiology; Glutamates; Hippocampus; In Vitro Techniques; Male; Oocytes; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stereoisomerism; Synaptic Membranes; Xenopus laevis | 1990 |
Blockade of parabrachial pressor responses by spinal administration of an N-methyl-D-aspartic acid receptor antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Electric Stimulation; Female; Injections, Intravenous; Injections, Spinal; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reference Values; Spinal Cord | 1990 |
Suppression of amygdaloid kindled convulsion following bilateral injection of 2-amino-7-phosphonoheptanoic acid into the substantia nigra of rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Anticonvulsants; Dominance, Cerebral; Electroencephalography; Evoked Potentials; Injections; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1990 |
N-methyl-D-aspartate receptors of ganglion cells in rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells; Valine | 1990 |
A unified approach to systematic isosteric substitution for acidic groups and application to NMDA antagonists related to 2-amino-7-phosphonoheptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Models, Molecular; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship | 1990 |
Attenuation of febrile seizures in epileptic chicks by N-methyl-D-aspartate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Chickens; Diaminopimelic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Fever; Phenotype; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Synaptic Membranes | 1990 |
Effect of 2-amino-7-phosphonoheptanoic acid (APH) on seizure susceptibility in the prepubescent and mature rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Injections, Intraventricular; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Effect of NMDA and 2-amino-7-phosphonoheptanoate focal injection into the ventrolateral thalamic nucleus on the high pressure neurological syndrome in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Central Nervous System Diseases; High Pressure Neurological Syndrome; Male; Microinjections; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamic Nuclei | 1990 |
Blockade of excitatory neurotransmission in the globus pallidus induces rigidity and akinesia in the rat: implications for excitatory neurotransmission in pathogenesis of Parkinson's diseases.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Corpus Striatum; Dose-Response Relationship, Drug; Globus Pallidus; Male; Movement Disorders; Muscle Rigidity; Parkinson Disease; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission | 1990 |
Excitatory amino acid antagonists and pentylenetetrazol-induced seizures during ontogenesis. I. The effects of 2-amino-7-phosphonoheptanoate.
Topics: 2-Amino-5-phosphonovalerate; Aging; Amino Acids; Animals; Anticonvulsants; Male; Motor Activity; Pentylenetetrazole; Premedication; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Seizures; Specific Pathogen-Free Organisms | 1990 |
Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electroencephalography; Epilepsy; Female; Injections, Intraventricular; Male; N-Methylaspartate; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Functional antagonists at the NMDA receptor complex exhibit antidepressant actions.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Dose-Response Relationship, Drug; Imipramine; Immobilization; Male; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stress, Psychological; Strychnine; Swimming; Synaptic Transmission | 1990 |
The effects of potassium-induced depolarization, glutamate receptor antagonists and N-methyl-D-aspartate on neuronal survival in cultured neocortex explants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cell Survival; Cerebral Cortex; Culture Techniques; Electrophysiology; Glutamates; N-Methylaspartate; Neurons; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1990 |
Dibenzocycloalkenimine (MK-801) stimulates phosphoinositide hydrolysis in rat cerebral cortical slices).
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atropine; Cerebral Cortex; Dizocilpine Maleate; Hydrolysis; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Phencyclidine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Zinc | 1990 |
Stereospecificity of N-MDA-induced functional deficits.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Hippocampus; Learning; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred F344; Stereoisomerism | 1990 |
Systemic approaches to modifying quinolinic acid striatal lesions in rats.
Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine | 1988 |
The glutamate analog 2-amino-4-phosphonobutyrate antagonizes synaptic transmission from cones to horizontal cells in the goldfish retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Darkness; Goldfish; In Vitro Techniques; Membrane Potentials; Perfusion; Photic Stimulation; Photoreceptor Cells; Synapses; Synaptic Transmission | 1989 |
Suppression of amygdaloid kindled convulsion following unilateral injection of 2-amino-7-phosphonoheptanoic acid (2-APH) into the substantia innominata of rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Basal Ganglia; Male; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Substantia Innominata | 1989 |
NMDA receptor antagonists can enhance or impair learning performance in animals.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gerbillinae; Male; Memory; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Differential effects of (D)- and (L)-homocysteic acid on the membrane potential of cat caudate neurons in situ.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Cats; Caudate Nucleus; Female; Homocysteine; Male; Membrane Potentials; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism | 1989 |
Epileptiform activity in vitro can produce long-term synaptic failure and persistent neuronal depolarization.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Epilepsy; Hippocampus; In Vitro Techniques; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1989 |
Studies on the potential neurotoxic and convulsant effects of increased blood levels of quinolinic acid in rats with altered blood-brain barrier permeability.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood-Brain Barrier; Cerebral Cortex; Electroencephalography; Hippocampus; Male; Motor Activity; Nervous System Diseases; Protons; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures | 1989 |
Preferential loss of GABAergic neurons in hypoxia-exposed neocortex slab cultures is attenuated by the NMDA receptor blocker D-2-amino-7-phosphonoheptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cell Hypoxia; Cell Survival; Cerebral Cortex; gamma-Aminobutyric Acid; Organ Culture Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
The specific NMDA receptor antagonist AP-7 attenuates focal ischemic brain injury.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Ischemic Attack, Transient; Kinetics; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Catalepsy; Globus Pallidus; Male; N-Methylaspartate; Nervous System Diseases; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Substantia Nigra; Syndrome | 1989 |
Involvement of N-methyl-D-aspartate (NMDA) receptors in respiratory rhythmogenesis.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Brain; Cats; Dibenzocycloheptenes; Dizocilpine Maleate; Phrenic Nerve; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Respiration; Vagus Nerve | 1989 |
A comparison of the anticonvulsant effects of competitive and non-competitive antagonists of the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Pentylenetetrazole; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1989 |
Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Oxadiazoles; Phenazocine; Potassium; Putamen; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
N-methyl-D-aspartate receptor activation is required for the induction of both early and late phases of long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors; Valine | 1989 |
Glucose deprivation neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; Glucose; L-Lactate Dehydrogenase; Mice; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Comparison of the properties of [3H]-D-2-amino-5-phosphonopentanoic acid and [3H]-DL-2-amino-7-phosphonoheptanoic acid binding to homogenates of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; In Vitro Techniques; Ligands; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Salts; Tritium; Valine | 1989 |
Solubilization of quisqualate-sensitive [3H]glutamate binding activity from rat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Octoxynol; Oxadiazoles; Polyethylene Glycols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Solubility | 1989 |
Intraventricular infusion of 2-amino-7-phosphonoheptanoate (APH) mitigates ischaemic brain damage.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Ischemia; Injections, Intraventricular; Male; Necrosis; Rats; Rats, Inbred Strains | 1989 |
NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Ketamine; Kynurenic Acid; Magnesium; Motor Neurons; N-Methylaspartate; Potassium; Rana pipiens; Spinal Cord; Valine | 1989 |
Giant synaptic potentials in immature rat CA3 hippocampal neurones.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Animals, Newborn; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Ketamine; Membrane Potentials; Phencyclidine; Picrotoxin; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Effects of 2-amino-7-phosphonoheptanoic acid on EEG of rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Electroencephalography; Electrophysiology; Male; Rats; Rats, Inbred Strains | 1985 |
Stimulation of [3H]norepinephrine release from hippocampal slices by excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurotoxins; Norepinephrine; Rats; Rats, Inbred Strains; Tetrodotoxin | 1989 |
N-methyl-D-aspartate induces recurrent synchronized burst activity in immature hippocampal CA3 neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Tetrodotoxin | 1989 |
Impaired motor coordination in mice induced by 2-amino-7-phosphonoheptanoic acid (APH), glutamic acid diethyl ester (GDEE), and other compounds.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Female; Glutamates; Mice; Psychomotor Performance | 1989 |
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
Long-term development of selective neuronal loss and the mechanism of protection by 2-amino-7-phosphonoheptanoate in a rat model of incomplete forebrain ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cell Survival; Cerebrovascular Circulation; Hippocampus; Ischemic Attack, Transient; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Inhibition of aminophylline-induced convulsions in mice by antiepileptic drugs and other agents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminophylline; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Female; Mice; N-Methylaspartate; Phenobarbital; Seizures; Synaptic Transmission; Valproic Acid | 1987 |
Excitatory amino acid receptor-mediated transmission of somatosensory evoked potentials in the rat thalamus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Electroencephalography; Evoked Potentials, Somatosensory; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Synaptic Transmission; Thalamic Nuclei; Thalamus | 1987 |
Role of the N-methyl-D-aspartate-type receptors in the development and maintenance of hippocampal kindling in rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Electric Stimulation; Hippocampus; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Decrease in excitatory transmission within the lateral habenula and the mediodorsal thalamus protects against limbic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Injections; Limbic System; Male; Muscimol; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission; Thalamus | 1988 |
[Action of phosphorus-containing aminocarboxylic acids on neuromuscular transmission in the blowfly].
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Animals; Depression, Chemical; Diptera; Dose-Response Relationship, Drug; Glutamates; Larva; Membrane Potentials; Neuromuscular Junction; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission | 1988 |
Homocysteic acid as a putative excitatory amino acid neurotransmitter: I. Postsynaptic characteristics at N-methyl-D-aspartate-type receptors on striatal cholinergic interneurons.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Choline; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Homocysteine; Interneurons; Magnesium; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Tachyphylaxis; Tiletamine | 1988 |
Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cortical Spreading Depression; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Excitatory amino acids: role in morphine excitation in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; Motor Activity; N-Methylaspartate; Oxadiazoles; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Muscle relaxant action of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Female; Glutamates; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Spasticity; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1985 |
Effects of two convulsant beta-carboline derivatives, DMCM and beta-CCM, on regional neurotransmitter amino acid levels and on in vitro D-[3H]aspartate release in rodents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Carbolines; Cerebellum; Cerebral Cortex; Convulsants; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamine; Hippocampus; Indoles; Male; Mice; Mice, Inbred DBA; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Seizures | 1985 |
Phosphonic analogues of excitatory amino acids raise the threshold for maximal electroconvulsions in mice.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Amino Acids, Dicarboxylic; Animals; Electroshock; Glutamates; Male; Mice; Seizures; Valine | 1985 |
A comparison of the effects of quinolinate and N-methyl-aspartate on neurons in rat piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Iontophoresis; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Rats; Valine | 1986 |
(+/-)-cis-2,3-Piperidine dicarboxylic acid is a partial N-methyl-D-aspartate agonist in the in vitro rat cerebellar cGMP model.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Ionic regulation of the binding of DL-2-amino-7-phosphono-[4,5-3H]heptanoic acid to synaptosome-enriched homogenates of rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding Sites; Calcium; Cerebral Cortex; Chlorides; Freezing; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Valine | 1986 |
Continuously infused 2-amino-7-phosphonoheptanoic acid antagonizes N-methyl-D-aspartate-induced elevations of cyclic GMP in vivo in multiple brain areas and chemically-induced seizure activity.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Barbiturates; Bicuculline; Brain; Brain Chemistry; Cyclic GMP; Female; Injections, Intraventricular; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains | 1986 |
Does the excitatory amino acid receptor antagonist 2-APH exhibit anxiolytic activity?
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anti-Anxiety Agents; Carbolines; Diazepam; Discrimination, Psychological; Drug Interactions; Male; Mice; Pentylenetetrazole; Rats; Rats, Inbred Strains | 1986 |
2-Amino-7-phosphonoheptanoic acid (AP7) produces discriminative stimuli and anticonflict effects similar to diazepam.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anti-Anxiety Agents; Anticonvulsants; Baclofen; Diazepam; Male; Methocarbamol; Muscle Relaxants, Central; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1986 |
Glutamate-evoked release of endogenous brain dopamine: inhibition by an excitatory amino acid antagonist and an enkephalin analogue.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Dopamine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1987 |
Involvement of N-methyl-D-aspartate receptors in the augmenting response in rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Electric Stimulation; Evoked Potentials; Male; Motor Cortex; Neural Pathways; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Somatosensory Cortex; Thalamic Nuclei; Valine | 1987 |
[3H]norepinephrine release from hippocampal slices is an in vitro biochemical tool for investigating the pharmacological properties of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tetrodotoxin | 1987 |
Possible role of excitatory amino acids in the convulsant action of catechol.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Catechols; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Electromyography; Female; Pipecolic Acids; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Seizures; Valine | 1988 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
Excitatory amino acid antagonists and endogenous aspartate and glutamate release from rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Tetrodotoxin; Valine | 1988 |
NMDA antagonists: lack of protective effect against hypoxic damage in CA1 region of hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Female; Hippocampus; Hypoxia, Brain; Membrane Potentials; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Enhancement of opioid cataleptic response by cortical frontal deafferentation or intrastriatal injection of NMDA-receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Catalepsy; Cerebral Cortex; Cerebral Ventricles; Corpus Striatum; Female; Kinetics; Methadone; Morphine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Valine | 1988 |
Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Dipeptides; Glutamates; Homocysteine; Iontophoresis; Ketamine; Male; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Valine | 1988 |
Epileptiform bursts elicited in CA3 hippocampal neurons by a variety of convulsants are not blocked by N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Hippocampus; In Vitro Techniques; Kainic Acid; Kindling, Neurologic; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate and glutamine in mouse brain cortex.
Topics: 2-Amino-5-phosphonovalerate; 3-Mercaptopropionic Acid; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Male; Mice; N-Methylaspartate; Valproic Acid | 1988 |
A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; In Vitro Techniques; N-Methylaspartate; Neurons; Piperazines; Rats; Reflex; Spine; Valine | 1988 |
Quinolinate neurotoxicity in cortical cell culture.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Kynurenic Acid; L-Lactate Dehydrogenase; Mice; Neuroglia; Pyridines; Quinolinic Acid; Quinolinic Acids | 1987 |
Quinolinic acid-induced seizures, but not nerve cell death, are associated with extracellular Ca2+ decrease assessed in the hippocampus by brain dialysis.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Calcium; Dialysis; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Tetrodotoxin; Veratridine | 1988 |
Pharmacology of the corticocaudate excitatory postsynaptic potential in the cat: evidence for its mediation by quisqualate- or kainate-receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cats; Caudate Nucleus; Cerebral Cortex; Evoked Potentials; Female; Kynurenic Acid; Male; Neural Pathways; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, Neurotransmitter; Synaptic Transmission | 1985 |
Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Electroencephalography; Hypoglycemia; Male; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1985 |
2-Amino-7-phosphonoheptanoic acid depresses gamma-motoneurons and polysynaptic reflexes in the cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cats; Depression, Chemical; Motor Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex; Spinal Cord | 1985 |
2-Amino-7-phosphonoheptanoic acid (2-APH) infusion into entopeduncular nucleus protects against limbic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Basal Ganglia; Male; Muscimol; Neural Inhibition; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1986 |
Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electroencephalography; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Stereotaxic Techniques; Substantia Nigra; Synaptic Transmission | 1986 |
Glutamate-containing dipeptides do not modulate ligand binding at excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Amino Acids; Aminopeptidases; Animals; Binding, Competitive; Dipeptides; Glutamates; Kainic Acid; Leucine; Male; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1986 |
2-Amino-7-phosphonoheptanoic acid, a selective N-methyl-D-aspartate antagonist, blocks swim-induced elevation of cerebellar cyclic guanosine monophosphate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellum; Cyclic GMP; Female; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Swimming | 1986 |
Neurotransmission in the pedunculopontine nucleus and pilocarpine-induced motor limbic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Basal Ganglia; Cerebellum; Limbic System; Male; Muscimol; Pilocarpine; Pons; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1987 |
Both competitive and non-competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Light; Male; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred F344 | 1988 |
Excitatory amino acids in synaptic excitation of rat striatal neurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Glutamates; Glutamine; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Synapses | 1988 |
The discriminative stimulus effects of N-methyl-D-aspartate antagonists in phencyclidine-trained rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Discrimination, Psychological; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Methohexital; N-Methylaspartate; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Specific antagonism of excitotoxic action of 'uncommon' amino acids assayed in organotypic mouse cortical cultures.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Amino Acids, Diamino; Animals; beta-Alanine; Cerebral Cortex; Culture Techniques; Cyanobacteria Toxins; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Neurotoxins; Osmolar Concentration; Pipecolic Acids | 1987 |
Specific antagonism of behavioral action of "uncommon" amino acids linked to motor-system diseases.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Diamino; Animals; beta-Alanine; Cerebral Ventricles; Cyanobacteria Toxins; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Motor Activity; Pipecolic Acids; Reference Values | 1987 |
Inhibition of the development of electrical kindling of the prepyriform cortex by daily focal injections of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Electric Stimulation; Electrodes, Implanted; Electrophysiology; Glutamine; Injections; Kindling, Neurologic; Male; Piperazines; Rats; Rats, Inbred Strains | 1988 |
2-Amino-7-phosphonoheptanoic acid inhibits insulin-induced convulsions and striatal aspartate accumulation in rats with frontal cortical ablation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Glucose; Insulin; Male; Rats; Rats, Inbred Strains; Seizures | 1987 |
The N-methyl-D-aspartate antagonist, 2-amino-7-phosphonoheptanoate, produces phencyclidine-like behavioral effects in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1987 |
Effects of L-cysteine-sulphinate and L-aspartate, mixed excitatory amino acid agonists, on the membrane potential of cat caudate neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cats; Caudate Nucleus; Cysteine; Female; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1987 |
Characterization of motor activity patterns induced by N-methyl-D-aspartate antagonists in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Gerbillinae; Ketamine; Motor Activity; N-Methylaspartate; Pipecolic Acids; Piperazines; Piperidines; Time Factors | 1987 |
Excitant amino acids and audiogenic seizures in the genetically epilepsy-prone rat. I. Afferent seizure initiation pathway.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Afferent Pathways; Amino Acids; Animals; Geniculate Bodies; Inferior Colliculi; Olivary Nucleus; Rats; Seizures | 1988 |
Excitant amino acids and audiogenic seizures in the genetically epilepsy-prone rat. II. Efferent seizure propagating pathway.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Efferent Pathways; Female; Male; Rats; Reticular Formation; Seizures; Substantia Nigra | 1988 |
Determination of the pharmacokinetics of 2-amino-7-phosphonoheptanoate in rat plasma and cerebrospinal fluid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Chromatography, High Pressure Liquid; Convulsants; Male; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1988 |
A simple method for quantitative electroencephalographic assessment of drugs with convulsant and anticonvulsant properties.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Diazepam; Electroencephalography; Hippocampus; Injections; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1986 |
Effect of 2-aminophosphonoheptanoic acid on the EEG of rats exposed to high pressure.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Central Nervous System Diseases; Electroencephalography; High Pressure Neurological Syndrome; Male; Myoclonus; Rats; Rats, Inbred Strains; Seizures; Tremor | 1986 |
Focal injection of 2-amino-7-phosphonoheptanoic acid into prepiriform cortex protects against pilocarpine-induced limbic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Limbic System; Male; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1986 |
Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid and muscimol in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Male; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Seizures | 1986 |
N-Methyl-D-aspartate and L-aspartate activate distinct receptors in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Limbic System; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1984 |
Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Ischemia; Hippocampus; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission | 1984 |
Phosphonate analogues of carboxylic acids as aminoacid antagonists on rat cortical neurones.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Drug Antagonism; Electric Conductivity; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; N-Methylaspartate; Neurons; Organophosphorus Compounds; Rats; Valine | 1981 |
alpha-Amino-omega-phosphono carboxylates block ibotenate but not kainate neurotoxicity in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Diseases; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Neurotoxins; Oxazoles; Pyrrolidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valine | 1982 |
Specific binding of [3H]+/- 2-amino-7-phosphono heptanoic acid to rat brain membranes in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Male; Mitochondria; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
A comparison of the anticonvulsant potency of (+/-) 2-amino-5-phosphonopentanoic acid and (+/-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Valine | 1983 |
The kindled amygdala model of epilepsy: anticonvulsant action of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Amygdala; Animals; Anticonvulsants; Epilepsy; Male; Rats; Rats, Inbred Strains; Valine | 1983 |
Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, Papio papio.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Glutamates; Papio; Photic Stimulation; Pipecolic Acids; Seizures; Valine | 1983 |
Quinolinic acid evokes [3H]acetylcholine release in striatal slices: mediation by NMDA-type excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Aminobutyrates; Animals; Corpus Striatum; Drug Interactions; In Vitro Techniques; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium; Valine | 1983 |
Suppression of audiogenic seizures in DBA/2 mice by two new dipeptide NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Glutamates; Glutamine; Mice; Mice, Inbred DBA; Seizures; Valine | 1984 |
The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Fasting; Glutamates; Glutamic Acid; Male; Myoclonus; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission; Syndrome; Tremor | 1984 |
Anticonvulsant action of amino acid antagonists against kindled hippocampal seizures.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Animals; Anticonvulsants; Cerebral Ventricles; Electric Stimulation; Hippocampus; Kindling, Neurologic; Male; Pyramidal Tracts; Rats; Rats, Inbred Strains; Seizures; Valine | 1984 |
The actions of 'selective' excitatory amino acid antagonists on the crustacean neuromuscular junction.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Anomura; Dipeptides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Neuromuscular Junction; Norleucine; Pyridines; Synaptic Transmission; Valine | 1984 |
Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Animals; Hippocampus; In Vitro Techniques; Male; Norleucine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Valine | 1984 |
Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Seizures | 1982 |
The effects of intrahippocampal ibotenic acid and their blockade by (-) 2-amino-7-phosphonoheptanoic acid: morphological and electroencephalographical analysis.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Hippocampus; Ibotenic Acid; Male; Neurons; Oxazoles; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1983 |
In vivo release of [3H]-purines by quinolinic acid and related compounds.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Kynurenic Acid; Male; N-Methylaspartate; Purines; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tritium | 1983 |
The organotypic tissue culture model of corticostriatal system used for examining amino acid neurotoxicity and its antagonism: studies on kainic acid, quinolinic acid and (-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Animals; Caudate Nucleus; Corpus Striatum; Culture Techniques; Dose-Response Relationship, Drug; Frontal Lobe; Kainic Acid; Microscopy, Electron; Models, Neurological; Nerve Degeneration; Pyridines; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1983 |
Glutamate-containing dipeptides enhance specific binding at glutamate receptors and inhibit specific binding at kainate receptors in rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Dipeptides; Glutamates; Male; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Kainic Acid; Tissue Distribution | 1984 |
On the interaction of 2-amino-7-phosphono-heptanoic acid and quinolinic acid in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Iontophoresis; Male; Mice; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Seizures | 1983 |
2-Amino-phosphonoheptanoic acid protects against the high pressure neurological syndrome.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsies, Myoclonic; Male; Rats; Rats, Inbred Strains; Seizures; Syndrome; Tremor | 1983 |
Ibotenate-induced neuronal degeneration in immature rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Catecholamines; Cerebellum; Corpus Striatum; Female; gamma-Aminobutyric Acid; Hippocampus; Ibotenic Acid; Male; Oxazoles; Rats; Rats, Inbred Strains | 1984 |
Behavioural and convulsant actions of two methyl esters of beta-carboline-3-carboxylic acid in photosensitive baboons and in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Carbolines; Convulsants; Indoles; Male; Mice; Mice, Inbred DBA; Papio; Photic Stimulation; Species Specificity; Time Factors | 1984 |
Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Caudate Nucleus; Electroshock; Haloperidol; Hippocampus; Injections; Male; Muscimol; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra | 1984 |
Effect of 2-amino-7-phosphonoheptanoic acid on regional brain amino acid levels in fed and fasted rodents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Brain; Fasting; Food; Glucose; Male; Mice; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
Isomers of 2-amino-7-phosphonoheptanoic acid as antagonists of neuronal excitants.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats | 1982 |
Uptake of a novel anticonvulsant compound, 2-amino-7-phosphono-[4,5-3H]heptanoic acid, into mouse brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Brain; Male; Mice; Mice, Inbred Strains; Time Factors; Tritium | 1983 |
2-amino-7-phosphonoheptanoic acid as an amino acid antagonist.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Organophosphorus Compounds; Rats; Spinal Cord; Stimulation, Chemical; Time Factors | 1982 |
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Apnea; Blood Pressure; Cats; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Piperazines; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Respiration; Solitary Nucleus; Vagotomy | 1995 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Stimulation of N-methyl-D-aspartate receptors in the rat nucleus reticularis thalami suppresses somatosensory evoked potentials.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Somatosensory; Male; Microinjections; N-Methylaspartate; Nerve Fibers; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thalamic Nuclei | 1994 |
Importance of nitric oxide for local increases of blood flow in rat cerebellar cortex during electrical stimulation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Amino Acid Oxidoreductases; Amino Acids; Animals; Anticonvulsants; Arginine; Carbon Dioxide; Cerebellar Cortex; Cerebrovascular Circulation; Drug Interactions; Electric Stimulation; Isomerism; Magnesium; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Tetrodotoxin | 1994 |
Visual and somatosensory evoked potentials are mediated by excitatory amino acid receptors in the thalamus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Electric Stimulation; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Male; Photic Stimulation; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus | 1994 |
Regulation of extracellular adenosine levels in the striatum of aging rats.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Aging; Amino Acids; Animals; Corpus Striatum; Enzyme Inhibitors; Extracellular Space; Male; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tubercidin | 1995 |
Non-NMDA receptors in the rostral ventrolateral medulla mediate somatosympathetic pressor responses.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Blood Pressure; Electric Stimulation; Female; Histocytochemistry; Ibotenic Acid; Kainic Acid; Medulla Oblongata; Neurons, Afferent; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve; Sympathetic Nervous System; Vagotomy | 1993 |
Pentamidine, an inhibitor of spinal flexor reflexes in rats, is a potent N-methyl-D-aspartate (NMDA) antagonist in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Drug Interactions; Electromyography; H-Reflex; Ibotenic Acid; Injections, Spinal; Male; N-Methylaspartate; Pentamidine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Stretch; Tibial Nerve | 1993 |
Thalamocortical and corticocortical excitatory postsynaptic potentials mediated by excitatory amino acid receptors in the cat motor cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Cats; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Male; Motor Cortex; Piperazines; Pyramidal Tracts; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus | 1995 |
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures | 1995 |
Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Brain; Brain Diseases; Embryonic and Fetal Development; Excitatory Amino Acids; Female; Glial Fibrillary Acidic Protein; Hypoxia; Ibotenic Acid; Male; Mice; N-Methylaspartate; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Midazolam and the N-methyl-D-aspartate (NMDA) receptor antagonist 2-amino-7-phosphonoheptanoic acid (AP-7) attenuate stress-induced expression of c-fos mRNA in the dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Gene Expression Regulation; Genes, fos; Hippocampus; Immobilization; In Situ Hybridization; Male; Midazolam; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stress, Physiological | 1994 |
Bilateral intranigral NMDA blockade increases status duration and neuronal injury from systemic kainic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Carbon Dioxide; Diazepam; Drug Synergism; Electroencephalography; Functional Laterality; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Injections, Intravenous; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neurons; Oxygen; Partial Pressure; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors | 1994 |
Deep prepiriform cortex modulates kainate-induced hippocampal injury.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Electroencephalography; Excitatory Amino Acids; GABA Antagonists; Hippocampus; Kainic Acid; Male; Neural Pathways; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Seizures; Synaptic Transmission | 1994 |
Sensitive and rapid behavioral differentiation of N-methyl-D-aspartate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Binding, Competitive; Central Nervous System Depressants; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Phenazocine; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine | 1994 |
NMDA and not non-NMDA receptor antagonists are protective against seizures induced by homocysteine in neonatal rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Dizocilpine Maleate; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Anxiety; Appetite Depressants; Carbolines; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; Male; Microinjections; Midazolam; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on spinal release of amino acids after development of acute arthritis in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acute Disease; Amino Acids; Analysis of Variance; Animals; Arthritis; Excitatory Amino Acids; Joints; Male; Microdialysis; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Differential sensitivity of growth hormone-releasing hormone and somatostatin release from perifused mouse hypothalamic fragments in response to glucose deficiency.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Deoxyglucose; Glucose; Glycolysis; Growth Hormone-Releasing Hormone; Hypothalamus; In Vitro Techniques; Indicators and Reagents; Mice; Perfusion; Potassium Chloride; Pyruvates; Pyruvic Acid; Radioimmunoassay; Somatostatin | 1993 |
Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Biphenyl Compounds; Disease Models, Animal; Glutamates; Glutamic Acid; Immunohistochemistry; Lidocaine; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Basal amygdaloid facilitation of midbrain periaqueductal gray elicited defensive rage behavior in the cat is mediated through NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Basal Metabolism; Cats; Cerebral Ventricles; Electric Stimulation; Female; Infusions, Parenteral; Male; Neural Pathways; Neurotransmitter Agents; Periaqueductal Gray; Rage; Receptors, N-Methyl-D-Aspartate | 1994 |
Release of 3H-noradrenaline by excitatory amino acids from rat mediobasal hypothalamus and the influence of aging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Amino Acids; Animals; Glutamates; Glutamic Acid; Hypothalamus, Middle; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Rats; Tritium | 1994 |
NMDA-dependent audiogenic seizures are differentially regulated by inferior colliculus subnuclei.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Brain Mapping; Epilepsy, Tonic-Clonic; Inferior Colliculi; N-Methylaspartate; Neurons; Rats; Seizures; Synaptic Transmission | 1994 |
Competitive NMDA receptor blockers reduce striatal glutamate accumulation in ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Extracellular Space; Glutamic Acid; In Vitro Techniques; Ischemic Attack, Transient; Male; Microdialysis; Neostriatum; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1994 |
Posterior piriform and perirhinal cortex relay seizures evoked from the area tempestas: role of excitatory and inhibitory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Entorhinal Cortex; Excitatory Amino Acid Antagonists; GABA Agonists; Kynurenic Acid; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Glutamate; Seizures | 1994 |
Competitive NMDA antagonists enhance the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amantadine; Amino Acids; Animals; Anticonvulsants; Catalepsy; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Ergolines; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperazines; Quinpirole; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1994 |
Injections of excitatory amino acid antagonists into the median raphe nucleus produce hippocampal theta rhythm in the urethane-anesthetized rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Anesthesia; Animals; Anticonvulsants; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Injections; Kainic Acid; Male; Quisqualic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Theta Rhythm; Urethane | 1994 |
In vivo assessment of prevention of white-noise-induced seizure in magnesium-deficient rats by N-methyl-D-aspartate receptor blockers.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Body Weight; Dizocilpine Maleate; Electrocardiography; Electroencephalography; Electrolytes; Magnesium Deficiency; Male; Noise; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 1994 |
In vivo regulation of extracellular adenosine levels in the cerebral cortex by NMDA and muscarinic receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Amino Acids; Animals; Cerebral Cortex; Male; Oxotremorine; Potassium; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate | 1994 |
The depressant effect of GYKI 52466 on spinal reflex transmission in rats is mediated via non-NMDA and benzodiazepine receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; H-Reflex; Injections, Spinal; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Reflex; Synaptic Transmission | 1994 |
Differential effects of compounds that act at strychnine-insensitive glycine receptors in a punishment procedure.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Behavior, Animal; Diazepam; Learning; Male; Memory; Mice; N-Methylaspartate; Punishment; Reaction Time; Receptors, Glycine; Strychnine | 1994 |
Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Humans; Middle Aged; Motor Neurons; Nerve Degeneration; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Developmental changes in NMDA and non-NMDA receptor-mediated synaptic potentials in rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Animals, Newborn; Cell Differentiation; Electric Stimulation; Frontal Lobe; Membrane Potentials; Neural Inhibition; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1993 |
Optical imaging of parallel fiber activation in the rat cerebellar cortex: spatial effects of excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebellar Cortex; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Long-lasting potentiation of field potentials in primary and secondary somatosensory cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Anesthesia; Animals; Anticonvulsants; Cats; Electric Stimulation; Evoked Potentials, Somatosensory; Ketamine; Microelectrodes; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Thalamic Nuclei | 1993 |
An experimental arthritis model in rats: the effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Aspartic Acid; Carrageenan; Glutamates; Glutamic Acid; Injections, Intra-Articular; Kaolin; Knee Joint; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord | 1993 |
Dependence of long-term depression on postsynaptic metabotropic glutamate receptors in visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Bicuculline; Cyclopentanes; Evoked Potentials; gamma-Aminobutyric Acid; Guanosine Diphosphate; Heparin; In Vitro Techniques; Kinetics; Neuronal Plasticity; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Synapses; Thionucleotides; Visual Cortex | 1993 |
Sympathoexcitation from the rostral ventrolateral medulla is mediated by spinal NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Electric Stimulation; Female; Glutamates; Glutamic Acid; Heart Rate; Histocytochemistry; Horseradish Peroxidase; Injections, Spinal; Medulla Oblongata; Pons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Sympathetic Nervous System | 1993 |
The contribution of NMDA and non-NMDA receptors to the light-evoked input-output characteristics of retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Ambystoma; Amino Acids; Animals; Darkness; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Light; Magnesium; Mathematics; Models, Neurological; Photic Stimulation; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Synapses | 1993 |
NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Dizocilpine Maleate; gamma-Aminobutyric Acid; Hippocampus; Male; Microdialysis; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Septal Nuclei; Tetrodotoxin | 1994 |
Evidence for the involvement of excitatory amino acid pathways in the development of precipitated withdrawal from acute and chronic morphine: an in vivo voltammetric study in the rat locus coeruleus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cerebral Ventricles; Dipeptides; Excitatory Amino Acid Antagonists; Infusions, Parenteral; Injections, Intraventricular; Locus Coeruleus; Male; Morphine; Morphine Dependence; Naloxone; Neurons; Potentiometry; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stereoisomerism; Substance Withdrawal Syndrome | 1993 |
gamma-Acetylenic GABA produces axon-sparing neurodegeneration after focal injection into the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminobutyrate Transaminase; Alkynes; Amino Acids; Aminocaproates; Animals; Anticonvulsants; Axons; Choline O-Acetyltransferase; Dizocilpine Maleate; Hippocampus; In Vitro Techniques; Kynurenic Acid; Lyases; Male; Nerve Degeneration; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Transaminases | 1993 |
N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of dextromethorphan in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Dextromethorphan; Electric Stimulation; Electromyography; H-Reflex; Injections, Intraperitoneal; Injections, Spinal; Male; Muscle Relaxation; Muscles; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reflex, Stretch | 1993 |
Antagonists of N-methyl-D-aspartate receptors block seizures induced by putrescine in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Dizocilpine Maleate; Electrocardiography; Electroencephalography; Male; Putrescine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Effect of K+ depolarization, tetrodotoxin, and NMDA receptor inhibition on extracellular adenosine levels in rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Amino Acids; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dipyridamole; Male; Perfusion; Potassium; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1993 |
Metabotropic glutamate receptors in the ventrolateral medulla of rats.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Blood Pressure; Cycloleucine; Dose-Response Relationship, Drug; Drug Combinations; Male; Medulla Oblongata; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical | 1993 |
Homocysteate-evoked release of acetylcholine from the rabbit retina.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Animals; Homocysteine; Magnesium; Neurotransmitter Agents; Quinoxalines; Rabbits; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Stereoisomerism; Stimulation, Chemical | 1996 |
The relationship between light-evoked synaptic excitation and spiking behaviour of salamander retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Amino Acids; Animals; Evoked Potentials, Visual; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Synapses | 1995 |
Amygdaloid kindling by repeated focal N-methyl-D-aspartate administration: comparison with electrical kindling.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Calcium; Excitatory Amino Acid Agonists; Kindling, Neurologic; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
Progesterone in vitro increases NMDA-evoked [3H] dopamine release from striatal slices in proestrus rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Corpus Striatum; Dizocilpine Maleate; Dopamine; Drug Synergism; Estrus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; N-Methylaspartate; Progesterone; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
Characterisation of N-methyl-D-aspartate (NMDA)-induced kindling.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amygdala; Animals; Anticonvulsants; Electroencephalography; Kindling, Neurologic; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors | 1996 |
Hyperosmotic activation of transmitter release from presynaptic terminals onto retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; Ambystomatidae; Amino Acids; Animals; Anticonvulsants; Cadmium; Cobalt; Convulsants; Excitatory Amino Acid Antagonists; Light; Membrane Potentials; Neurotransmitter Agents; Organ Culture Techniques; Osmotic Pressure; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Retinal Ganglion Cells; Strychnine; Sucrose | 1995 |
Excitatory amino acid antagonists in the rostral ventromedial medulla inhibit mesencephalic morphine analgesia in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Analgesics, Opioid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections; Male; Medulla Oblongata; Mesencephalon; Morphine; Pain Measurement; Pain Threshold; Periaqueductal Gray; Rats; Rats, Sprague-Dawley | 1996 |
Protection by NMDA receptor antagonists against seizures induced by intracerebral administration of 4-aminopyridine.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Anticonvulsants; Convulsants; Dizocilpine Maleate; Electroencephalography; Injections, Intraventricular; Male; Motor Cortex; Neuroprotective Agents; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Stereotaxic Techniques | 1996 |
NMDA receptors in the midbrain periaqueductal gray mediate hypothalamically evoked hissing behavior in the cat.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Cats; Efferent Pathways; Female; Hypothalamus; Male; Microinjections; Nerve Fibers; Periaqueductal Gray; Rage; Receptors, N-Methyl-D-Aspartate | 1996 |
[The influence of intrathecal NMDA receptor antagonist on the isoflurane MAC and on the motor function].
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1996 |
NMDA antagonist blockade of AT8 tau immunoreactive changes in neuronal cultures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Fetus; Fluorescent Antibody Technique; Kynurenic Acid; Microscopy, Confocal; Neurons; Piperidines; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; tau Proteins | 1996 |
Differential action of NMDA antagonists on cholinergic neurotoxicity produced by N-methyl-D-aspartate and quinolinic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Choline O-Acetyltransferase; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
The role of excitatory neurotransmitters in seizure-induced neuronal injury in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood Pressure; Cerebral Cortex; Diazepam; Electroencephalography; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Male; Microdialysis; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Status Epilepticus | 1996 |
Arrest of neuronal migration by excitatory amino acids in hamster developing brain.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; Animals; Animals, Newborn; Brain; Cell Differentiation; Cell Division; Cell Movement; Cricetinae; DNA; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Matrix; Female; Humans; Ibotenic Acid; Male; Mesocricetus; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate | 1996 |
NMDA as well as non-NMDA receptors in phrenic nucleus mediate respiratory effects of carotid chemoreflex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carotid Body; Chemoreceptor Cells; Drug Combinations; Excitatory Amino Acid Antagonists; Male; Microinjections; Neck; Phrenic Nerve; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Respiration; Spinal Cord; Stimulation, Chemical | 1997 |
Spinal muscarinic, glutamatergic and GABAergic receptor systems in cardiovascular regulation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Baclofen; Blood Pressure; Carbachol; Dizocilpine Maleate; Heart Rate; Male; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate; Receptors, Muscarinic; Spinal Cord | 1997 |
Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a mu-opiate receptor agonist.
Topics: 2-Amino-5-phosphonovalerate; Alfentanil; Analgesics, Opioid; Animals; Cats; Excitatory Amino Acid Antagonists; Female; Glycine Agents; Injections, Spinal; Male; Models, Neurological; Nerve Fibers; Neurons; Pressure; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Sensory Thresholds; Strychnine | 1996 |
Non-NMDA but not NMDA blockade at deep prepiriform cortex protects against hippocampal cell death in status epilepticus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Cell Death; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Neuroprotective Agents; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reproducibility of Results; Status Epilepticus | 1997 |
Excitatory amino acid receptor involvement in peripheral nociceptive transmission in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Hyperalgesia; Injections, Intra-Articular; Knee Joint; Male; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Synaptic Transmission | 1997 |
Anticonvulsant action of both NMDA and non-NMDA receptor antagonists against seizures induced by homocysteine in immature rats.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamates; Homocysteine; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
The NMDA and GABA-A receptors in behavioral activity of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Behavior, Animal; Bicuculline; Conditioning, Classical; Drug Combinations; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Mental Recall; Motor Activity; Pattern Recognition, Visual; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1996 |
Comparable dose-dependent inhibition of AP-7 sensitive strychnine-induced allodynia and paw pinch-induced nociception by mexiletine in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Foot; Hyperesthesia; Male; Mexiletine; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Strychnine | 1997 |
The estimation of interactions between arginine-vasopressin (AVP) and NMDA receptors in memory and learning processes.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine Vasopressin; Biguanides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Learning; Male; Memory; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
APH, an N-methyl-D-aspartate receptor antagonist, blocks the metaphit-induced audiogenic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Anticonvulsants; Convulsants; Electroencephalography; Male; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
The effect of baclofen and AP-7 on selected behavior in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Baclofen; Behavior, Animal; Cognition; Drug Interactions; Excitatory Amino Acid Antagonists; Exploratory Behavior; GABA Agonists; GABA-B Receptor Agonists; Injections, Intraventricular; Male; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Apomorphine; Columbidae; Discrimination, Psychological; Dopamine Agonists; Excitatory Amino Acid Antagonists; Generalization, Stimulus; Lidocaine; Microinjections; Neural Conduction; Nucleus Accumbens | 1998 |
Effects of 2-amino-7-phosphonohepatanoic acid, melatonin or NG-nitro-L-arginine on cyanide or N-methyl-D-aspartate-induced neurotoxicity in rat cortical cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Free Radicals; In Vitro Techniques; L-Lactate Dehydrogenase; Melatonin; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Poisons; Potassium Cyanide; Rats | 1998 |
Modulation of neuronal activity by glial cells in the retina.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Astrocytes; Bicuculline; Calcium; Cell Communication; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; Male; Neurotransmitter Agents; Photic Stimulation; Quinoxalines; Rats; Rats, Inbred Strains; Retinal Ganglion Cells; Strychnine; Thapsigargin | 1998 |
Evidence that NMDA-dependent limbic neural plasticity in the right hemisphere mediates pharmacological stressor (FG-7142)-induced lasting increases in anxiety-like behavior. Study 2--The effects on behavior of block of NMDA receptors prior to injection of
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Arousal; Brain Mapping; Carbolines; Cats; Dominance, Cerebral; Efferent Pathways; Excitatory Amino Acid Antagonists; GABA Antagonists; Limbic System; Long-Term Potentiation; Male; Neuronal Plasticity; Periaqueductal Gray; Predatory Behavior; Rats; Receptors, N-Methyl-D-Aspartate; Ventromedial Hypothalamic Nucleus | 1998 |
Effect of MK-801 on seizures induced by exposure to hyperbaric oxygen: comparison with AP-7.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Anticonvulsants; Cerebral Cortex; Cerebrovascular Circulation; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Hyperbaric Oxygenation; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures | 1998 |
Interaction of memantine and amantadine with agonist-unbound NMDA-receptor channels in acutely isolated rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Amantadine; Animals; Aspartic Acid; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Memantine; Membrane Potentials; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1998 |
Analysis of excitatory and inhibitory spontaneous synaptic activity in mouse retinal ganglion cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Bicuculline; Cadmium; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine Agents; Kinetics; Mice; Mice, Inbred C57BL; Neural Inhibition; Reaction Time; Receptors, GABA-A; Receptors, Glycine; Retinal Ganglion Cells; Strychnine; Synaptic Transmission; Tetrodotoxin; Virulence Factors, Bordetella | 1998 |
Rewarding effects elicited by the microinjection of either AMPA or NMDA glutamatergic antagonists into the ventral tegmental area revealed by an intracranial self-administration paradigm in mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred BALB C; Microinjections; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration; Sulpiride | 1998 |
Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Blood Pressure; Cats; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Microdialysis; Neuralgia; Neurons, Afferent; Nociceptors; Pain Threshold; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stimulation, Chemical; Strychnine | 1998 |
Mediodorsal thalamus plays a critical role in the development of limbic motor seizures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Brain Mapping; Carbon Radioisotopes; Deoxyglucose; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Muscimol; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Thalamus; Time Factors; Vigabatrin | 1998 |
The anticonvulsant potency of (+/-)-2-Amino-7-phosphonoheptanoic acid and (+/-)-2-amino-5-phosphonovaleric acid against metaphit-induced audiogenic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Anticonvulsants; Excitatory Amino Acid Antagonists; Male; Phencyclidine; Rats; Rats, Wistar; Seizures | 1998 |
Effects of ventrolateral medullary NMDA-receptor antagonism on biogenic amines and pressor response to muscle contraction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Excitatory Amino Acid Antagonists; Male; Medulla Oblongata; Microdialysis; Muscle Contraction; Muscle, Skeletal; Neostriatum; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin | 1998 |
Modulation of the audiogenic seizure network by noradrenergic and glutamatergic receptors of the deep layers of superior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Adrenergic alpha-Agonists; Animals; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Inferior Colliculi; Male; Microinjections; Norepinephrine; Phenylephrine; Rats; Rats, Mutant Strains; Receptors, Adrenergic; Receptors, N-Methyl-D-Aspartate; Reticular Formation; Superior Colliculi | 1999 |
Cardiovascular responses to microinjections of excitatory amino acids into the area postrema of the rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Cerebral Ventricles; Cycloleucine; Decerebrate State; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Tachycardia; Urethane | 1999 |
The periaqueductal grey is a critical site in the neuronal network for audiogenic seizures: modulation by GABA(A), NMDA and opioid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; Isoxazoles; Male; Microinjections; Naloxone; Narcotic Antagonists; Nerve Net; Periaqueductal Gray; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Seizures | 1999 |
Actions of NMDA and cholinergic receptor antagonists in the rostral ventromedial medulla upon beta-endorphin analgesia elicited from the ventrolateral periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Analgesia; Animals; beta-Endorphin; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Medulla Oblongata; Muscarinic Antagonists; Nicotinic Antagonists; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine | 1999 |
NMDA glutamatergic blockade of nucleus accumbens disrupts acquisition but not consolidation in a passive avoidance task.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Excitatory Amino Acid Antagonists; Male; Microinjections; Nucleus Accumbens; Rats; Receptors, N-Methyl-D-Aspartate | 1999 |
Short-term block of Na+/K+-ATPase in neuro-glial cell cultures of cerebellum induces glutamate dependent damage of granule cells.
Topics: 2-Amino-5-phosphonovalerate; Aniline Compounds; Animals; Binding, Competitive; Calcium; Cells, Cultured; Cerebellum; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Lithium; N-Methylaspartate; Neuroglia; Ouabain; Rats; Rats, Wistar; Rhodamine 123; Sodium-Potassium-Exchanging ATPase; Xanthenes | 1999 |
High pressure enhanced NMDA activity in the striatum and the globus pallidus: relationships with myoclonia and locomotor and motor activity in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Atmospheric Pressure; Corpus Striatum; Excitatory Amino Acid Antagonists; Globus Pallidus; High Pressure Neurological Syndrome; Male; Motor Activity; Myoclonus; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 2000 |
Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Energy Metabolism; Epilepsy; Excitatory Amino Acid Antagonists; Glucose; Homocysteine; Injections, Intraventricular; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2000 |
[Effect of the isoosmotic solution with decreased sodium level on mitochondria of cultured granule cells from the cerebellum].
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cells, Cultured; Cerebellum; Cobalt; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Membrane Potentials; Mitochondria; Neurons; Osmosis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium; Solutions; Sucrose | 2000 |
Modulation of extracellular glutamate and pressor response to muscle contraction during NMDA-receptor blockade in the rostral ventrolateral medulla.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glutamic Acid; Heart Rate; Medulla Oblongata; Muscle Contraction; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Administration of either non-NMDA receptor agonists or NMDA receptor antagonists into the substantia nigra or the globus pallidus reduces the psychostimulant effect of high helium pressure on locomotor activity in rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atmospheric Pressure; Excitatory Amino Acid Agonists; Globus Pallidus; Helium; Injections; Kainic Acid; Male; Motor Activity; Myoclonus; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1999 |
Guanine nucleotides block agonist-driven 45Ca2+ influx in chick embryo retinal explants.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Calcium Radioisotopes; Chick Embryo; Excitatory Amino Acid Antagonists; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Monophosphate; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Thionucleotides | 2000 |
Behavioral effects in the elevated plus maze of an NMDA antagonist injected into the dorsal hippocampus: influence of restraint stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Injections; Male; Maze Learning; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stress, Physiological | 2000 |
Intracellular calcium reduces light-induced excitatory post-synaptic responses in salamander retinal ganglion cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Ambystoma; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Ion Channels; Light; Patch-Clamp Techniques; Protein Kinase Inhibitors; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Sodium | 2001 |
Topical bicuculline to the rat spinal cord induces highly localized allodynia that is mediated by spinal prostaglandins.
Topics: 2-Amino-5-phosphonovalerate; Administration, Topical; Animals; Bicuculline; Blood Pressure; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Antagonists; Heart Rate; Male; Motor Neurons; Nitrobenzenes; Pain Measurement; Posterior Horn Cells; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Spinal Cord; Sulfonamides; Touch | 2001 |
Differential effects of NMDA antagonists microinjections into the nucleus reticularis pontis caudalis on seizures induced by pentylenetetrazol in the rat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Pentylenetetrazole; Pons; Rats; Rats, Wistar; Reticular Formation; Seizures | 2001 |
Audiogenic seizure susceptibility is induced by termination of continuous infusion of gamma-aminobutyric acid or an N-methyl-D-aspartic acid Antagonist into the inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Behavior, Animal; Catheterization; Disease Susceptibility; Drug Administration Routes; Epilepsy, Reflex; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Inferior Colliculi; Infusion Pumps, Implantable; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2001 |
NMDA or non-NMDA receptor antagonists attenuate increased Fos expression in spinal dorsal horn GABAergic neurons after intradermal injection of capsaicin in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blotting, Western; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Functional Laterality; gamma-Aminobutyric Acid; Inflammation; Injections, Intradermal; Interneurons; Male; Membrane Potentials; Neural Conduction; Neural Inhibition; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 2001 |
Aldrin-induced stimulation of locomotor activity and brain regional glutamate.
Topics: 2-Amino-5-phosphonovalerate; Aldrin; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Insecticides; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 2001 |
Excitatory amino acid receptor antagonist 2APH may improve local CBF during cerebral ischemia in cats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Ischemia; Cats; Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Male; Receptors, N-Methyl-D-Aspartate | 2001 |
The effects of N-methyl-D-aspartate antagonist 2-amino-7-phosphonoheptanoic acid microinfusions into the adult male rat substantia nigra pars reticulata are site-specific.
Topics: 2-Amino-5-phosphonovalerate; Animals; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flurothyl; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Substantia Nigra; Synaptic Transmission | 2001 |
Anxiolytic-like effects of AP7 injected into the dorsolateral or ventrolateral columns of the periaqueductal gray of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety; Consummatory Behavior; Excitatory Amino Acid Antagonists; Injections; Male; Pain Measurement; Periaqueductal Gray; Punishment; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate | 2002 |
AP-7 into the nucleus accumbens disrupts acquisition but does not affect consolidation in a passive avoidance task.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Electroshock; Injections; Male; Nucleus Accumbens; Rats; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Stereotaxic Techniques | 2002 |
Caudal ventrolateral medulla mediates the depressor response elicited by the greater splanchnic nerve afferent stimulation in rats.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; Heart Rate; Kynurenic Acid; Lidocaine; Male; Medulla Oblongata; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Splanchnic Nerves | 2002 |
Fast-acting excitatory amino acids are involved in the enhancement of the aversiveness of the electrical stimulation of the inferior colliculus by systemic injections of muscimol.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Inferior Colliculi; Injections, Intraperitoneal; Male; Microinjections; Muscimol; Rats; Rats, Wistar | 2002 |
The motivational valence of nicotine in the rat ventral tegmental area is switched from rewarding to aversive following blockade of the alpha7-subunit-containing nicotinic acetylcholine receptor.
Topics: 2-Amino-5-phosphonovalerate; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conditioning, Operant; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Microinjections; Motivation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Ventral Tegmental Area | 2003 |
Neurons in the periaqueductal gray are critically involved in the neuronal network for audiogenic seizures during ethanol withdrawal.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Alcohol Withdrawal Seizures; Analysis of Variance; Animals; Behavior, Animal; Epilepsy, Reflex; Ethanol; Excitatory Amino Acid Antagonists; Male; Microinjections; Nerve Net; Neurons; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
The role of ionotropic receptors of glutaminic acid in cardiovascular system. A. The influence of ionotropic receptor NMDA agonist - 1R,3R-ACPD and antagonist - DL-AP7 on the systemic pressure in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Chlorisondamine; Cycloleucine; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2003 |
Ionotropic glutamate-receptor antagonists inhibit the aversive effects of nitric oxide donor injected into the dorsolateral periaqueductal gray of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Male; Molsidomine; Motor Activity; Nitric Oxide; Nitric Oxide Donors; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Time Factors | 2004 |
Antidepressant-like effects of NMDA-receptor antagonist injected into the dorsal hippocampus of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Excitatory Amino Acid Antagonists; Hippocampus; Immobilization; Injections, Intraventricular; Male; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Stress, Physiological | 2004 |
The 5-HT receptor antagonist M100,907 prevents extracellular glutamate rising in response to NMDA receptor blockade in the mPFC.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Space; Fluorobenzenes; Glutamic Acid; Male; Microdialysis; Nicotine; Piperazines; Piperidines; Potassium Chloride; Prefrontal Cortex; Rats; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin | 2004 |
Role of glutamate ionotropic receptors in the dorsomedial hypothalamic nucleus on anxiety and locomotor behavior.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Dorsomedial Hypothalamic Nucleus; Male; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 2004 |
Neurons in the amygdala play an important role in the neuronal network mediating a clonic form of audiogenic seizures both before and after audiogenic kindling.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Amygdala; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Epilepsy, Reflex; Excitatory Amino Acid Antagonists; Female; Kindling, Neurologic; Male; Microinjections; Nerve Net; Neurons; Rats; Rats, Mutant Strains; Time Factors | 2005 |
Carotid sinus nerve section abolishes NMDA evoked respiratory effects in anaesthetised rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Blood Pressure; Carotid Sinus; Denervation; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Pulmonary Ventilation; Rats; Rats, Wistar; Respiration; Tidal Volume; Time Factors; Vagotomy | 2005 |
Cortical epileptic afterdischarges in immature rats are differently influenced by NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dizocilpine Maleate; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Motor Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 2005 |
Evidence for the perirhinal cortex as a requisite component in the seizure network following seizure repetition in an inherited form of generalized clonic seizures.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Entorhinal Cortex; Epilepsy; Epilepsy, Reflex; Excitatory Amino Acid Antagonists; Female; Kindling, Neurologic; Male; Nerve Net; Rats; Rats, Mutant Strains | 2005 |
[Inhibition of metaphit-induced audiogenic seizures by 2-amino-7-phosphonoheptanoic acid].
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Male; Phencyclidine; Rats; Rats, Wistar; Seizures | 2002 |
Medial prefrontal cortex NMDA receptors and nitric oxide modulate the parasympathetic component of the baroreflex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Baroreflex; Blood Pressure; Drug Administration Routes; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parasympathetic Nervous System; Phenylephrine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sympathomimetics; Time Factors; Wakefulness | 2006 |
Differential effects of glutamate receptor antagonists on dorsal horn neurons responding to colorectal distension in a neonatal colon irritation rat model.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Catheterization; Colon; Disease Models, Animal; Excitatory Amino Acid Antagonists; Irritable Bowel Syndrome; Male; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2005 |
c-Fos expression increase in NADPH-diaphorase positive neurons after exposure to a live cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arousal; Brain; Cats; Depression, Chemical; Excitatory Amino Acid Antagonists; Fear; Immunoenzyme Techniques; Male; Nitric Oxide Synthase; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Social Environment | 2006 |
Sex-specific control of flurothyl-induced tonic-clonic seizures by the substantia nigra pars reticulata during development.
Topics: 2-Amino-5-phosphonovalerate; Acrylates; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Castration; Convulsants; Female; Flurothyl; GABA Agonists; GABA-A Receptor Agonists; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Sex Factors; Substantia Nigra; Testosterone Propionate | 2006 |
In vivo electrical stimulation of rabbit retina: effect of stimulus duration and electrical field orientation.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Electric Stimulation; Electroretinography; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Neurons, Afferent; Quinoxalines; Rabbits; Retina; Retinal Ganglion Cells; Time Factors; Visual Cortex | 2006 |
Lack of interaction between NMDA and cholecystokinin-2 receptor-mediated neurotransmission in the dorsolateral periaqueductal gray in the regulation of rat defensive behaviors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gastrointestinal Agents; Male; Maze Learning; N-Methylaspartate; Periaqueductal Gray; Quinazolinones; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Signal Transduction; Tetragastrin | 2006 |
Involvement of dorsolateral periaqueductal gray N-methyl-D-aspartic acid glutamate receptors in the regulation of risk assessment and inhibitory avoidance behaviors in the rat elevated T-maze.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Anxiety; Ethosuximide; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Hippocampus; Male; Microinjections; N-Methylaspartate; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Risk-Taking | 2006 |
Non-vagal apnea evoked by intra-common carotid artery injection of N-methyl-D-aspartic acid (NMDA) in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Apnea; Blood Pressure; Carotid Sinus; Denervation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intra-Arterial; Male; N-Methylaspartate; Rats; Rats, Wistar; Respiration; Vagotomy; Vagus Nerve | 2006 |
Role of the amygdala in ethanol withdrawal seizures.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Alcohol Withdrawal Seizures; Amygdala; Animals; Behavior, Animal; Central Nervous System Depressants; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electroencephalography; Ethanol; Excitatory Amino Acid Antagonists; Male; Rats; Rats, Sprague-Dawley | 2007 |
Involvement of glutamatergic receptors in the nucleus cuneiformis in modulating morphine-induced antinociception in rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Nociceptors; Pain; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 2007 |
Endogenous D-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina.
Topics: 2-Amino-5-phosphonovalerate; Animals; D-Amino-Acid Oxidase; Drug Interactions; Electrophoresis, Capillary; Excitatory Amino Acid Antagonists; Hydro-Lyases; In Vitro Techniques; Light; Membrane Potentials; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Serine; Time Factors; Urodela | 2007 |
Glutamatergic ionotropic blockade within accumbens disrupts working memory and might alter the endocytic machinery in rat accumbens and prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; Adaptor Protein Complex 2; Animals; Behavior, Animal; Endocytosis; Excitatory Amino Acid Antagonists; Glutamine; Immunoblotting; Male; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2007 |
Microinjection of muscimol into the periaqueductal gray suppresses cardiovascular and neuroendocrine response to air jet stress in conscious rats.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; Air; Animals; Blood Pressure; Cardiovascular System; Consciousness; Excitatory Amino Acid Antagonists; GABA Agonists; Heart Rate; Male; Microinjections; Muscimol; Neurosecretory Systems; Periaqueductal Gray; Quinoxalines; Rats; Rats, Sprague-Dawley; Stress, Physiological | 2008 |
Tegmental pedunculopontine glutamate and GABA-B synapses mediate morphine reward.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Morphine; N-Methylaspartate; Narcotics; Pedunculopontine Tegmental Nucleus; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Glutamate; Reward | 2009 |
Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fear; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors | 2009 |
Substance P and glutamate receptor antagonists improve the anti-arthritic actions of dexamethasone in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dexamethasone; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Glutamic Acid; Injections, Intra-Articular; Isoindoles; Knee Joint; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P; Time Factors | 2010 |
Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Inferior Colliculi; Male; Microinjections; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synaptic Transmission | 2010 |
Network oscillations in rod-degenerated mouse retinas.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Age Factors; Animals; Carbenoxolone; Cyclooxygenase Inhibitors; Disease Models, Animal; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glutamic Acid; Glycine; In Vitro Techniques; Light; Male; Meclofenamic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Net; Neural Inhibition; Periodicity; Pyridazines; Quinoxalines; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Sodium Channel Blockers; Statistics as Topic; Tetrodotoxin | 2011 |
Blockade of NMDA or NO in the dorsal premammillary nucleus attenuates defensive behaviors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Behavior, Animal; Cats; Defense Mechanisms; Excitatory Amino Acid Antagonists; Fear; Freezing Reaction, Cataleptic; Locomotion; Male; Mammillary Bodies; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Statistics, Nonparametric | 2011 |
Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Estrogen Replacement Therapy; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Models, Animal; N-Methylaspartate; Neurotransmitter Agents; Ovariectomy; Pregnanolone; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
The role of the glutathione system in seizures induced by diphenyl diselenide in rat pups.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzene Derivatives; Buthionine Sulfoximine; Catalase; Female; Glutathione; Glutathione Peroxidase; Kynurenic Acid; Male; Organoselenium Compounds; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2011 |
Brain superoxide anion formation in immature rats during seizures: protection by selected compounds.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Homocysteine; Infusions, Intraventricular; Male; Metalloporphyrins; Proline; Rats; Rats, Wistar; Seizures; Statistics, Nonparametric; Superoxides; Time Factors | 2012 |
L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Inferior Colliculi; Male; Microinjections; N-Methylaspartate; Nitroarginine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Time Factors | 2012 |
Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Male; Maze Learning; Periaqueductal Gray; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; TRPV Cation Channels | 2013 |
Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat.
Topics: 2-Amino-5-phosphonovalerate; Adrenocorticotropic Hormone; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Blood Pressure; Cardiovascular System; Denervation; Excitatory Amino Acid Antagonists; Heart Rate; Male; Melanocyte-Stimulating Hormones; Paraventricular Hypothalamic Nucleus; Pressoreceptors; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptors, Corticotropin; Splanchnic Nerves; Sympathetic Nervous System | 2012 |
Effects of CA1 glutamatergic systems upon memory impairments in cholestatic rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; CA1 Region, Hippocampal; Cholestasis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Memory; Memory Disorders; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2013 |
Involvement of dorsal hippocampus glutamatergic and nitrergic neurotransmission in autonomic responses evoked by acute restraint stress in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arterial Pressure; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Heart Rate; Hippocampus; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitrites; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Signal Transduction; Skin Temperature; Stress, Psychological; Tail | 2014 |
Antidepressant properties of aqueous macerate from Gladiolus dalenii corms.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Fluoxetine; Hindlimb Suspension; Imipramine; Iridaceae; Male; Medicine, African Traditional; Mice; Motor Activity; N-Methylaspartate; Phytotherapy; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming | 2014 |
Involvement of the nucleus accumbens shell glutamatergic system in ACPA-induced impairment of inhibitory avoidance memory consolidation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acids; Avoidance Learning; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Memory; Memory Disorders; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Piperidines; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2014 |
The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Learning; CA1 Region, Hippocampal; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Mice; Microinjections; N-Methylaspartate; Piperidines; Pyrazoles; Receptors, N-Methyl-D-Aspartate | 2015 |
Blockade of glutamatergic transmission in perirhinal cortex impairs object recognition memory in macaques.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Kynurenic Acid; Macaca; Male; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Temporal Lobe; Time Factors; Visual Perception | 2015 |
The role of NMDA receptors of the medial septum and dorsal hippocampus on memory acquisition.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; CA1 Region, Hippocampal; Excitatory Amino Acid Antagonists; Locomotion; Male; Memory; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2016 |
NMDA-NO signaling in the dorsal and ventral hippocampus time-dependently modulates the behavioral responses to forced swimming stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cobalt; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hippocampus; Male; Nitric Oxide; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming | 2016 |
Stimulation of the hypothalamic arcuate nucleus increases brown adipose tissue nerve activity via hypothalamic paraventricular and dorsomedial nuclei.
Topics: 2-Amino-5-phosphonovalerate; Adipose Tissue, Brown; alpha-MSH; Animals; Arcuate Nucleus of Hypothalamus; Dorsomedial Hypothalamic Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA-A Receptor Agonists; Glutamic Acid; Immunohistochemistry; Male; Microinjections; Muscimol; N-Methylaspartate; Neural Inhibition; Paraventricular Hypothalamic Nucleus; Pro-Opiomelanocortin; Quinoxalines; Rats; Rats, Wistar; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Stilbamidines; Sympathetic Nervous System; Temperature; Thermogenesis; Vesicular Glutamate Transport Proteins | 2016 |
Blockade of glutamatergic transmission in the primate basolateral amygdala suppresses active behavior without altering social interaction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Basolateral Nuclear Complex; Behavior, Animal; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Interpersonal Relations; Macaca nemestrina; Male; Motor Activity; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Social Behavior; Synaptic Transmission | 2017 |
The Nitric Oxide Donor SIN-1-Produced Panic-Like Behaviour And Fear-Induced Antinociception Are Modulated By NMDA Receptors In The Anterior Hypothalamus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fear; Hypothalamus, Anterior; Male; Mice; Mice, Inbred C57BL; Microinjections; Molsidomine; Nitric Oxide Donors; Panic; Receptors, N-Methyl-D-Aspartate | 2018 |
Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Apomorphine; Arginine; Capsaicin; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Exploratory Behavior; Glutamic Acid; Male; Microinjections; Nitric Oxide; Nitroprusside; Rats; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Swimming | 2019 |
Nitric oxide in the dorsal periaqueductal gray mediates the panic-like escape response evoked by exposure to hypoxia.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Arginine; Escape Reaction; Hypothalamus; Hypoxia; Male; Maze Learning; Microinjections; Motor Activity; Nitric Oxide; Nitrites; Panic; Periaqueductal Gray; Rats | 2019 |
Inhibition of the left medial prefrontal cortex (mPFC) prolongs the social defeat-induced anxiogenesis in mice: Attenuation by NMDA receptor blockade in the right mPFC.
Topics: 2-Amino-5-phosphonovalerate; Adaptation, Psychological; Animals; Anxiety; Behavior, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; Male; Maze Learning; Mice; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Social Defeat; Stress, Psychological | 2020 |