Page last updated: 2024-09-04

2-amino-5-hydroxy-4-oxopentanoic acid and aminolevulinic acid

2-amino-5-hydroxy-4-oxopentanoic acid has been researched along with aminolevulinic acid in 20 studies

*Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. [MeSH]

*Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. [MeSH]

Compound Research Comparison

Studies
(2-amino-5-hydroxy-4-oxopentanoic acid)
Trials
(2-amino-5-hydroxy-4-oxopentanoic acid)
Recent Studies (post-2010)
(2-amino-5-hydroxy-4-oxopentanoic acid)
Studies
(aminolevulinic acid)
Trials
(aminolevulinic acid)
Recent Studies (post-2010) (aminolevulinic acid)
21056,4756652,740

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's7 (35.00)18.2507
2000's4 (20.00)29.6817
2010's6 (30.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Tsuruo, T; Yamaguchi, H; Yamaguchi, M; Yamaki, H1
Glazebrook, MA; Vining, LC; White, RL1
Imamura, H; Nishimura, T; Saito, H; Suzuki, H; Yamaguchi, H; Yamaguchi, M; Yamaki, H1
Nishimura, T; Shinoda, T; Suzuki, H; Tago, Y; Yamaguchi, H; Yamaguchi, M; Yamaki, H1
Nishimura, T; Shinoda, T; Yamaguchi, H; Yamaguchi, M; Yamaki, H1
Hiratani, T; Nagate, T; Omura, S; Uchida, K; Watanabe, N; Yamaguchi, H1
Chedrawy, EG; Glazebrook, MA; Smith, KC; Vining, LC; White, RL1
Le, Y; Smith, KC; Vining, LC; White, RL1
Isonishi, S; Nozato, N; Ochiai, K; Ohtake, Y; Okamoto, A; Tagashira, M1
Bareich, DC; Nazi, I; Wright, GD1
Berghuis, AM; Ejim, L; Green, K; Honek, JF; Hughes, DW; Jacques, SL; Kinach, R; Koteva, K; Lai, HK; Mirza, IA; Wright, GD1
Daniel, RK1
Guo, MX; Wang, HW; Wang, XL; Xu, SZ1
Mittal, B; Srivastava, A; Srivastava, K1
Asman, M; Cuber, P; Nowak, M; Siuda, K; Solarz, K; Strzelczyk, J; Szilman, E; Szilman, P; Trapp, G; Wiczkowski, A1
Alfredsson, L; Askling, J; Chen, CY; Costenbader, KH; Hiraki, LT; Jiang, X; Karlson, EW; Klareskog, L; Malspeis, S; Sparks, JA1
Beheshti, HR; Davari, G; Fahim, NK; Feizy, J; Janati, SS1
Abdalla Saleh, HA; El-Bahnasawy, MM; Megahed, LA; Morsy, TA1
Cheng, Z; Sun, JW1
Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS1

Reviews

2 review(s) available for 2-amino-5-hydroxy-4-oxopentanoic acid and aminolevulinic acid

ArticleYear
Lassa fever or lassa hemorrhagic fever risk to humans from rodent-borne zoonoses.
    Journal of the Egyptian Society of Parasitology, 2015, Volume: 45, Issue:1

    Topics: Aminolevulinic Acid; Animals; Humans; Lassa Fever; Rodentia; Zoonoses

2015
Posterior Reversible Encephalopathy Syndrome.
    Current pain and headache reports, 2021, Feb-25, Volume: 25, Issue:3

    Topics: Acute Chest Syndrome; Aminolevulinic Acid; Anemia, Sickle Cell; Autoimmune Diseases; Blood-Brain Barrier; Brain Edema; Cerebrovascular Circulation; COVID-19; Cytokines; Eclampsia; Endothelium; Female; Headache; Homeostasis; Humans; Hypertension; Magnetic Resonance Imaging; Posterior Leukoencephalopathy Syndrome; Pre-Eclampsia; Pregnancy; Prognosis; Renal Insufficiency; SARS-CoV-2; Seizures; Vasospasm, Intracranial; Vision Disorders

2021

Other Studies

18 other study(ies) available for 2-amino-5-hydroxy-4-oxopentanoic acid and aminolevulinic acid

ArticleYear
Mechanism of action of an antifungal antibiotic, RI-331, (S) 2-amino-4-oxo-5-hydroxypentanoic acid; kinetics of inactivation of homoserine dehydrogenase from Saccharomyces cerevisiae.
    The Journal of antibiotics, 1992, Volume: 45, Issue:5

    Topics: Aminolevulinic Acid; Antifungal Agents; Aspartate Kinase; Aspartate-Semialdehyde Dehydrogenase; Homoserine Dehydrogenase; Kinetics; Saccharomyces cerevisiae

1992
Growth morphology of Streptomyces akiyoshiensis in submerged culture: influence of pH, inoculum, and nutrients.
    Canadian journal of microbiology, 1992, Volume: 38, Issue:2

    Topics: Aminolevulinic Acid; Antifungal Agents; Carbon; Culture Media; Hydrogen-Ion Concentration; Immersion; Nitrogen; Phosphates; Spores, Fungal; Streptomyces

1992
The mechanism of antifungal action of (S)-2-amino-4-oxo-5-hydroxypentanoic acid, RI-331: the inhibition of homoserine dehydrogenase in Saccharomyces cerevisiae.
    Biochemical and biophysical research communications, 1990, Apr-30, Volume: 168, Issue:2

    Topics: Alcohol Oxidoreductases; Aminolevulinic Acid; Antifungal Agents; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Homoserine; Homoserine Dehydrogenase; Kinetics; Saccharomyces cerevisiae

1990
The mode of antifungal action of (S)2-amino-4-oxo-5-hydroxypentanoic acid, RI-331.
    The Journal of antibiotics, 1990, Volume: 43, Issue:4

    Topics: Amino Acids; Aminolevulinic Acid; Antifungal Agents; DNA, Fungal; Fungal Proteins; Nephelometry and Turbidimetry; RNA, Fungal; Saccharomyces cerevisiae

1990
Unique mechanism of action of an antifungal antibiotic RI-331.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:7

    Topics: Amino Acids; Aminolevulinic Acid; Antifungal Agents; Cell-Free System; DNA, Fungal; Fungal Proteins; Microbial Sensitivity Tests; Protein Synthesis Inhibitors; RNA, Fungal; Saccharomyces cerevisiae

1988
RI-331, a new antifungal antibiotic.
    Annals of the New York Academy of Sciences, 1988, Volume: 544

    Topics: Aminolevulinic Acid; Animals; Antifungal Agents; Fungi; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests

1988
Nutrient effects on growth and the production of 5-hydroxy-4-oxonorvaline by Streptomyces akiyoshiensis.
    Canadian journal of microbiology, 1993, Volume: 39, Issue:5

    Topics: Aminolevulinic Acid; Antifungal Agents; Aspartic Acid; Culture Media; Hydrogen-Ion Concentration; Magnesium Sulfate; Nitrates; Phosphates; Potassium Compounds; Starch; Streptomyces

1993
Mutants of Streptomyces akiyoshiensis blocked in 5-hydroxy-4-oxonorvaline production.
    The Journal of antibiotics, 1996, Volume: 49, Issue:1

    Topics: Aminolevulinic Acid; Antifungal Agents; Mutation; Streptomyces

1996
5-Hydroxy-4-oxo-L-norvaline depletes intracellular glutathione: a new modulator of drug resistance.
    Bioscience, biotechnology, and biochemistry, 1999, Volume: 63, Issue:11

    Topics: Aminolevulinic Acid; Buthionine Sulfoximine; Drug Resistance, Multiple; Female; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Ovarian Neoplasms; Saccharomyces cerevisiae; Soil Microbiology; Streptomyces; Tumor Cells, Cultured

1999
Simultaneous in vitro assay of the first four enzymes in the fungal aspartate pathway identifies a new class of aspartate kinase inhibitor.
    Chemistry & biology, 2003, Volume: 10, Issue:10

    Topics: Acetyltransferases; Aminobutyrates; Aminolevulinic Acid; Antifungal Agents; Aspartate Kinase; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Binding Sites; Enzyme Inhibitors; Homoserine Dehydrogenase; Kinetics; Oligopeptides; Organophosphorus Compounds; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2003
Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase.
    Chemistry & biology, 2003, Volume: 10, Issue:10

    Topics: Aminolevulinic Acid; Antifungal Agents; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Homoserine Dehydrogenase; Kinetics; NAD; Structure-Activity Relationship

2003
Diced cartilage grafts in rhinoplasty surgery: current techniques and applications.
    Plastic and reconstructive surgery, 2008, Volume: 122, Issue:6

    Topics: Aminolevulinic Acid; Cartilage; Fascia; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nose; Retrospective Studies; Rhinoplasty

2008
Treatment of skin cancer and pre-cancer using topical ALA-PDT--a single hospital experience.
    Photodiagnosis and photodynamic therapy, 2008, Volume: 5, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Erythroplasia; Female; Hospitalization; Humans; Keratosis, Actinic; Male; Middle Aged; Paget Disease, Extramammary; Photochemotherapy; Precancerous Conditions; Skin Neoplasms

2008
Polymorphisms in ERCC2, MSH2, and OGG1 DNA repair genes and gallbladder cancer risk in a population of Northern India.
    Cancer, 2010, Jul-01, Volume: 116, Issue:13

    Topics: Aminolevulinic Acid; Case-Control Studies; DNA Glycosylases; Female; Gallbladder Neoplasms; Gallstones; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; India; Male; Middle Aged; MutS Homolog 2 Protein; Polymorphism, Single Nucleotide; Risk; Xeroderma Pigmentosum Group D Protein

2010
The risk of exposure to Anaplasma phagocytophilum, Borrelia burgdorferi sensu lato, Babesia sp. and co-infections in Ixodes ricinus ticks on the territory of NiepoĊ‚omice forest (southern Poland).
    Annals of parasitology, 2013, Volume: 59, Issue:1

    Topics: Aminolevulinic Acid; Anaplasma phagocytophilum; Animals; Babesia; Bacterial Infections; Borrelia burgdorferi Group; Humans; Ixodes; Poland; Tick Infestations; Trees

2013
Improved performance of epidemiologic and genetic risk models for rheumatoid arthritis serologic phenotypes using family history.
    Annals of the rheumatic diseases, 2015, Volume: 74, Issue:8

    Topics: Aged; Alcohol Drinking; Aminolevulinic Acid; Area Under Curve; Arthritis, Rheumatoid; Autoantibodies; Body Mass Index; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Humans; Logistic Models; Male; Middle Aged; Peptides, Cyclic; Phenotype

2015
Survey of aflatoxins in rice from Iran using immunoaffinity column clean-up and HPLC with fluorescence detection.
    Food additives & contaminants. Part B, Surveillance, 2010, Volume: 3, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Aminolevulinic Acid; Chromatography, Affinity; Chromatography, High Pressure Liquid; Food Analysis; Food Contamination; Iran; Maximum Allowable Concentration; Seeds; Sensitivity and Specificity; Spectrometry, Fluorescence

2010
[Treatment of high-risk and complicate foreign bodies in respiratory tract].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2017, Jul-05, Volume: 31, Issue:13

    Topics: Aminolevulinic Acid; Bronchi; Bronchoscopes; Bronchoscopy; Foreign Bodies; Humans; Retrospective Studies

2017