Compounds > 2-amino-3-methylimidazo(4,5-f)quinoline
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2-amino-3-methylimidazo(4,5-f)quinoline and quinoxalines

2-amino-3-methylimidazo(4,5-f)quinoline has been researched along with quinoxalines in 88 studies

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-199019 (21.59)18.7374
1990's54 (61.36)18.2507
2000's10 (11.36)29.6817
2010's5 (5.68)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brams, A; de Meester, C1
Alldrick, AJ; Coutts, TM; Ho, TA; Rowland, IR1
Fay, LB; Turesky, RJ1
Adamson, RH; Schut, HA; Snyderwine, EG; Thorgeirsson, SS; Thorgeirsson, UP1
Felton, JS; Fultz, E; Knize, MG; Roper, M; Shen, NH; Turteltaub, KW1
Ilett, KF; Kadlubar, FF; Minchin, RF; Reeves, PT; Teitel, CH1
Alexander, J; Holme, JA; Wallin, H1
Bucci, T; Dooley, KL; Fu, PP; Kadlubar, FF; Von Tungeln, LS1
Gustafsson, JA; Kleman, M; Mason, G; Overvik, E1
Boncristiani, G; Loprieno, G; Loprieno, N2
Butler, MA; Kadlubar, FF; Lang, NP; Teitel, CH; Turesky, RJ1
Hirose, M; Nagao, M; Ochiai, M; Overvik, E; Sugimura, T1
Esumi, H; Kudo, M; Ogura, T; Sugimura, T1
Fukushima, S; Hakoi, K; Hasegawa, R; Ito, N; Iwasaki, S; Nagao, M; Shirai, T; Sugimura, T; Takaba, K; Wakabayashi, K1
Boobis, AR; Davies, DS; Gooderham, NJ; Lynch, AM; Murray, S1
Adamson, RH; Schut, HA; Snyderwine, EG; Sugimura, T; Takayama, S; Thorgeirsson, SS; Thorgeirsson, UP; Turesky, RJ1
Ito, N; Ozaki, K; Takahashi, S; Tsuda, H; Yamaguchi, S1
Burgess, WM; Huggett, A; McManus, ME; Quattrochi, LC; Tukey, RH; Veronese, ME1
Aeschbacher, HU; Forster, CM; Skipper, PL; Tannenbaum, SR; Trudel, LJ; Turesky, RJ; Würzner, HP1
Wada, O; Yanagisawa, H1
Aeschbacher, HU; Ruch, E1
Ayrton, AD; Bass, SL; Flatt, PR; Ioannides, C; Trinick, J; Walker, R1
Jones, RC; Weisburger, JH1
Aeschbacher, HU; Bur, H; Huynh-Ba, T; Milon, H; Turesky, RJ1
Alldrick, AJ; Rowland, IR1
Alexander, J; Wallin, H1
Alldrick, AJ; Rowland, IR; Wise, A1
Abu-Shakra, A; Ioannides, C; Walker, R1
Liu, ZC; Nagao, M; Sugimura, T; Wakabayashi, K; Zhang, XM1
Manabe, S; Wada, O; Yanagisawa, H1
Beamand, JA; Howes, AJ; Rowland, IR1
Hasegawa, H; Kato, T; Ohgaki, H; Sato, S; Suenaga, M; Sugimura, T; Takayama, S1
Caderni, G; Dolara, P; Salvadori, M; Santoni, G1
Goto, T; Kinae, N; Masui, T; Nagao, M; Sugimura, T; Takahashi, M; Tomita, I; Wakabayashi, K; Yamamoto, M1
Hayatsu, H; Hayatsu, T; Matsui, Y; Ohara, Y; Oka, T1
Buchi, GH; Pfund, RA; Tannenbaum, SR; Turesky, RJ; Wishnok, JS1
Hayashi, K; Kasai, H; Miyazawa, T; Nishimura, S; Watanabe, T; Yokoyama, S1
Diachenko, GW; Hargraves, WA; Jackson, LS; Stroup, WH1
Sadrieh, N; Snyderwine, EG1
Deguchi, T; Hashimoto, H; Itoh, S; Kamataki, T; Sawada, M; Yanagawa, Y1
Hao, NJ; Lee, H; Lin, MY1
Grivas, S; Klungsøyr, L; Knapstad, A; Vikse, R1
Sasaki, YF; Shirasu, Y1
Kato, R; Nagata, K; Ozawa, S; Yamazoe, Y1
Dolbeare, FA; Felton, JS; Fultz, E; Knize, MG1
Deguchi, T; Gonzalez, FJ; Kamataki, T; Sawada, M; Yanagawa, Y1
Carroll, KL; Dolbeare, FA; Felton, JS; Knize, MG; Moore, DH1
Chiarelli, MP; Kaderlik, KR; Kadlubar, FF; Lang, NP; Mulder, GJ; Teitel, CH; Turesky, RJ1
Kadlubar, FF; Ketterer, B; Lang, NP; Lin, D; Meyer, DJ1
Boobis, AR; Davies, DS; Edwards, RJ; Gant, TW; Murray, BP; Murray, S; Neubert, D; Schulz, T; Thorgeirsson, SS1
Burgard, S; Edenharder, R; John, K; Kurz, P; Seeger, K1
Davis, CD; Schut, HA; Snyderwine, EG1
Blanck, A; Gustafsson, JA; Kleman, MI; Overvik, E; Porsch-Hällström, I1
Ghoshal, A; Snyderwine, EG1
Skipper, PL; Stillwell, WG; Tannenbaum, SR; Turesky, RJ1
Davis, CD; Nouso, K; Roller, PP; Schut, HA; Snyderwine, EG1
Adamson, RH; Davis, CD; Schut, HA; Snyderwine, EG; Thorgeirsson, SS; Thorgeirsson, UP1
Dacquel, EJ; Davis, CD; Schut, HA; Snyderwine, EG; Thorgeirsson, SS1
Fay, LB; Turesky, RJ; Welti, DH1
Adamson, RH; Buonarati, MH; Snyderwine, EG; Turesky, RJ; Turteltaub, KW1
Adamson, RH; Davis, CD; Schut, HA; Snyderwine, EG; Thorgeirsson, SS1
Akaike, T; Maeda, H; Sato, K1
Adamson, RH; Dalgard, DW; Thorgeirsson, UP1
Felton, JS; Hopmans, EC; Knize, MG; Salmon, CP1
Adamson, RH; Davis, CD; Nagao, M; Sadrieh, N; Schut, HA; Snyderwine, EG; Sugimura, T; Thorgeirsson, SS; Thorgeirsson, UP; Turesky, RJ; Turteltaub, KW1
Akasaka, M; Matsusaka, N; Nishidate, E; Ohta, T; Saga, A; Sasaki, YF; Tsuda, S; Watanabe-Akanuma, M1
Barton, PT; Beamand, JA; Lake, BG; Price, RJ; Tredger, JM1
Cole, KJ; Grover, PL; Marquardt, H; Martin, FL; Pfau, W; Phillips, DH; Venitt, S1
Akaike, T; Maeda, H; Sawa, T; Yubisui, T1
Degawa, M; Konno, Y; Moore, MA; Nakashita, K; Sekine, K; Takasuka, N; Tsuda, H; Uehara, N1
Ryu, DY; Snyderwine, EG; Thorgeirsson, SS; Weidner, V1
Darroudi, F; Knasmüller, S; Kundi, M; Land, SJ; Parzefall, W; Sanyal, R; Schwab, CE; Wang, CY1
Amantana, A; Dashwood, RH; Orner, GA; Provost, C; Santana-Rios, G; Wu, SY1
Brooks, M; Hott, LL; Moslener, M; Novak, M; Rajagopal, S; Toth, K1
Bello, J; Lopez de Cerain, A; Perez, C1
Borgen, E; Skog, K1
Hirose, M; Imazawa, T; Ishii, Y; Kanki, K; Kitamura, Y; Kuroiwa, Y; Nishikawa, A; Umemura, T1
Abramsson-Zetterberg, L; Durling, LJ1
Bianchi, F; Careri, M; Corradini, C; Elviri, L; Mangia, A; Zagnoni, I1
Knasmüller, S; Koller, V; Sontag, G; Stidl, R1
Libudzisz, Z; Nowak, A1
Doll, MA; Hein, DW; Howarth, AL; McGregor, WG; Metry, KJ; Neale, JR; Pierce, WM; States, JC1
Liao, GZ; Wang, GY; Xu, XL; Zhang, YJ; Zhou, GH1
Filipič, M; Pezdirc, M; Žegura, B1
Dennis, C; Karim, F; Smith, JS1
Agim, ZS; Cannon, JR; Cruz-Hernandez, A; McCabe, GP; Montenegro, PC; Rochet, JC1

Reviews

2 review(s) available for 2-amino-3-methylimidazo(4,5-f)quinoline and quinoxalines

ArticleYear
Metabolism of heterocyclic aromatic amines and strategies of human biomonitoring.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Animals; Biotransformation; Blood Proteins; Carcinogens; Cooking; Cytochrome P-450 Enzyme System; Environmental Monitoring; Fishes; Hot Temperature; Humans; Inactivation, Metabolic; Intestinal Absorption; Meat; Mutagens; Primates; Quinolines; Quinoxalines; Rodentia

1995
Superoxide radical generation from heterocyclic amines.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Amines; Animals; Carcinogens; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Heterocyclic Compounds; Humans; Kinetics; Microsomes, Liver; Mutagenicity Tests; Mutagens; NADH Dehydrogenase; NADP; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Spin Labels; Superoxides

1995

Other Studies

86 other study(ies) available for 2-amino-3-methylimidazo(4,5-f)quinoline and quinoxalines

ArticleYear
Mutagenic potency of heterocyclic amines towards Salmonella typhimurium; possible causes of variability in the results observed.
    Mutation research, 1992, Volume: 280, Issue:2

    Topics: Dose-Response Relationship, Drug; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Reproducibility of Results; Salmonella typhimurium

1992
Inhibition of the metabolism of mutagens occurring in food by arachidonic acid.
    Mutation research, 1992, Volume: 269, Issue:2

    Topics: Aflatoxin B1; Animals; Antimutagenic Agents; Arachidonic Acid; Biotransformation; DNA Repair; Food; Imidazoles; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium

1992
Electron impact and fast atom bombardment mass spectrometric analysis of the food-borne carcinogens 2-amino-3-methylimidazo [4,5-f] quinoline, 2-amino-3,8-dimethylimidazo [4,5-f] quinoxaline and their metabolites.
    Biological mass spectrometry, 1992, Volume: 21, Issue:9

    Topics: Carcinogens; Food Analysis; Glucuronates; Quinolines; Quinoxalines; Spectrometry, Mass, Fast Atom Bombardment; Sulfates

1992
Metabolic activation and genotoxicity of heterocyclic arylamines.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7 Suppl

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; DNA; Heterocyclic Compounds; Imidazoles; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Polychlorinated Dibenzodioxins; Quinolines; Quinoxalines; Salmonella

1992
Chemical analysis, prevention, and low-level dosimetry of heterocyclic amines from cooked food.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7 Suppl

    Topics: DNA; Food Analysis; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Meat; Mutagenicity Tests; Quinolines; Quinoxalines

1992
Direct O-acetylation of N-hydroxy arylamines by acetylsalicylic acid to form carcinogen-DNA adducts.
    Carcinogenesis, 1992, Volume: 13, Issue:4

    Topics: Acetylation; Aminobiphenyl Compounds; Aspirin; Carcinogens; DNA; Fluorenes; Imidazoles; Quinolines; Quinoxalines

1992
Covalent binding of food carcinogens MeIQx, MeIQ and IQ to DNA and protein in microsomal incubations and isolated rat hepatocytes.
    Pharmacology & toxicology, 1992, Volume: 70, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; DNA; Male; Microsomes, Liver; Mutagens; Protein Binding; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains

1992
Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse.
    Cancer letters, 1992, Mar-15, Volume: 62, Issue:3

    Topics: Aminobiphenyl Compounds; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Imidazoles; Liver Neoplasms, Experimental; Male; Mice; Mutagens; Quinolines; Quinoxalines

1992
Effects of the food mutagens MeIQx and PhIP on the expression of cytochrome P450IA proteins in various tissues of male and female rats.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: Animals; Binding, Competitive; Blotting, Northern; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation; Imidazoles; Intestines; Kidney; Liver; Lung; Male; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA

1990
An experimental approach to identifying the genotoxic risk from cooked meat mutagens.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:6

    Topics: Administration, Oral; Animals; Cattle; Cell Line; Chromosome Aberrations; Cooking; Cricetinae; Cricetulus; DNA; Female; Food Contamination; Humans; Male; Meat; Mice; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Risk Factors; Tissue Distribution

1991
An experimental approach to identifying the genotoxic risk by cooked meat mutagens.
    Advances in experimental medicine and biology, 1991, Volume: 289

    Topics: Animals; Bone Marrow; Cell Line; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Humans; Lymphocytes; Male; Meat Products; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Protein Binding; Quinolines; Quinoxalines; Salmonella typhimurium; Tissue Distribution

1991
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Topics: Acetylation; Amines; Animals; Biotransformation; Carcinogens; Colon; Cytochrome P-450 Enzyme System; Cytosol; Heterocyclic Compounds; Humans; Imidazoles; Liver; Microsomes, Liver; Mutagens; Oxidation-Reduction; Quinolines; Quinoxalines; Rats

1991
The formation of heart DNA adducts in F344 rat following dietary administration of heterocyclic amines.
    Mutation research, 1991, Volume: 256, Issue:1

    Topics: Administration, Oral; Aging; Amines; Animals; Carbolines; Diet; DNA; DNA Damage; Heart; Imidazoles; Kinetics; Liver; Male; Myocardium; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1991
Mutational activation of c-Ha-ras gene in squamous cell carcinomas of rat Zymbal gland induced by carcinogenic heterocyclic amines.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Codon; Ear Neoplasms; Ear, External; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mutagens; Mutation; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Sebaceous Gland Neoplasms

1991
Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses.
    Carcinogenesis, 1991, Volume: 12, Issue:5

    Topics: Animals; Body Weight; Carbolines; Carcinogens; Drug Synergism; Enzyme Induction; Glutathione Transferase; Imidazoles; Immunohistochemistry; Liver; Liver Neoplasms; Male; Organ Size; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1991
The measurement of MeIQx adducts with mouse haemoglobin in vitro and in vivo: implications for human dosimetry.
    Carcinogenesis, 1991, Volume: 12, Issue:6

    Topics: Animals; Carbon Radioisotopes; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Hydrolysis; In Vitro Techniques; Mice; Microsomes; Mutagens; Quinolines; Quinoxalines

1991
Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates.
    Princess Takamatsu symposia, 1990, Volume: 21

    Topics: Animals; Chromatography, High Pressure Liquid; DNA; DNA Damage; Dose-Response Relationship, Immunologic; Imidazoles; Liver Neoplasms, Experimental; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines

1990
Comparison of initiation potential of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in an in vivo carcinogen bioassay system.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Enzyme Induction; Galactosamine; Glutathione Transferase; Hepatectomy; Liver Neoplasms, Experimental; Male; Mutagens; Organ Size; Phenobarbital; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1990
Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: 2-Acetylaminofluorene; Adolescent; Adult; Aged; Benzo(a)pyrene; Cell Line; Child; Cytochrome P-450 Enzyme System; Food Contamination; Gene Expression; Humans; Hydroxylation; Imidazoles; Microsomes, Liver; Middle Aged; Quinolines; Quinoxalines

1990
Purification of the food-borne carcinogens 2-amino-3-methylimidazo [4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in heated meat products by immunoaffinity chromatography.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Hot Temperature; Immunologic Techniques; Meat; Mutagens; Quinolines; Quinoxalines; Radioimmunoassay

1989
Significant increase of IQ-type heterocyclic amines, dietary carcinogens in the plasma of patients with uremia just before induction of hemodialysis treatment.
    Nephron, 1989, Volume: 52, Issue:1

    Topics: Adult; Carcinogens; Chromatography, High Pressure Liquid; Diet; Female; Humans; Male; Middle Aged; Mutagens; Quinolines; Quinoxalines; Renal Dialysis; Uremia

1989
Effect of heterocyclic amines and beef extract on chromosome aberrations and sister chromatid exchanges in cultured human lymphocytes.
    Carcinogenesis, 1989, Volume: 10, Issue:3

    Topics: Animals; Cattle; Cells, Cultured; Chromosome Aberrations; DNA Damage; Dose-Response Relationship, Drug; Humans; Lymphocytes; Meat; Mutagens; Quinolines; Quinoxalines; Sister Chromatid Exchange

1989
Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens.
    Chemico-biological interactions, 1988, Volume: 68, Issue:3-4

    Topics: Animals; Biotransformation; Carbolines; Carcinogens; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Insulin; Isoenzymes; Male; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Mutagenicity Tests; Mutagens; Niacinamide; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains

1988
Inhibition of aminoimidazoquinoxaline-type and aminoimidazol-4-one-type mutagen formation in liquid reflux models by L-tryptophan and other selected indoles.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:2

    Topics: Indoles; Mutagens; Quinolines; Quinoxalines; Structure-Activity Relationship; Tryptophan

1988
Analysis of mutagenic heterocyclic amines in cooked beef products by high-performance liquid chromatography in combination with mass spectrometry.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1988, Volume: 26, Issue:6

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Hot Temperature; Mass Spectrometry; Meat; Mutagenicity Tests; Quinolines; Quinoxalines

1988
Distribution of radiolabelled [2-14C]IQ and MeIQx in the mouse.
    Toxicology letters, 1988, Volume: 44, Issue:1-2

    Topics: Administration, Oral; Animals; Carbon Radioisotopes; Carcinogens; Chromatography, Thin Layer; Female; Gastrointestinal Contents; Intestinal Absorption; Mice; Mice, Inbred BALB C; Quinolines; Quinoxalines; Tissue Distribution

1988
A model system for studying covalent binding of food carcinogens MeIQx, MeIQ and IQ to DNA and protein.
    IARC scientific publications, 1988, Issue:89

    Topics: Animals; Biotransformation; Carcinogens; DNA; Food Analysis; In Vitro Techniques; Microsomes, Liver; Mutagens; Protein Binding; Quinolines; Quinoxalines; Rats

1988
The hepatic conversion of some heterocyclic amines to bacterial mutagens is modified by dietary fat and cholesterol.
    Mutagenesis, 1987, Volume: 2, Issue:3

    Topics: Animals; Biotransformation; Cattle; Cholesterol, Dietary; Dietary Fats; Hot Temperature; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Salmonella typhimurium

1987
Effect of tryptamine on the mutagenic activity of 2-amino-3-methylimidazo(4,5-f) quinoline (IQ) and related azaarenes in the Ames test.
    Mutagenesis, 1987, Volume: 2, Issue:1

    Topics: Animals; Aroclors; Biotransformation; Chlorodiphenyl (54% Chlorine); Cytosol; Enzyme Induction; In Vitro Techniques; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Species Specificity; Tryptamines

1987
Mutagenic and carcinogenic heterocyclic amines in Chinese cooked foods.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: China; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cooking; Diet; Food Analysis; Heterocyclic Compounds; Imidazoles; Mutagenicity Tests; Mutagens; Mutation; Neoplasms; Quinolines; Quinoxalines

1988
Detection of IQ-type heterocyclic amines in dialysis fluid of uremic patients treated by peritoneal dialysis.
    Nihon Jinzo Gakkai shi, 1987, Volume: 29, Issue:9

    Topics: Adult; Female; Humans; Male; Middle Aged; Mutagens; Peritoneal Dialysis, Continuous Ambulatory; Quinolines; Quinoxalines; Uremia

1987
Induction of unscheduled DNA synthesis in rat and hamster hepatocytes by cooked food mutagens.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1986, Volume: 24, Issue:5

    Topics: Animals; Biotransformation; Carbolines; Cricetinae; DNA; DNA Repair; Liver; Male; Mesocricetus; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Species Specificity

1986
Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx.
    Princess Takamatsu symposia, 1985, Volume: 16

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Carcinoma, Squamous Cell; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Stomach Neoplasms

1985
Mammalian cell DNA damage by some heterocyclic food mutagens is correlated with their potency in the Ames test.
    Mutation research, 1985, Volume: 144, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; DNA; Food Analysis; Food Handling; Mice; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium

1985
Quantification of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in beef extracts by liquid chromatography with electrochemical detection (LCEC).
    Carcinogenesis, 1985, Volume: 6, Issue:8

    Topics: Animals; Cattle; Chromatography, Liquid; Meat; Mutagens; Quinolines; Quinoxalines

1985
Characterization of mutagenic fractions in beef extract and in cooked ground beef. Use of blue-cotton for efficient extraction.
    Gan, 1983, Volume: 74, Issue:4

    Topics: Adsorption; Animals; Cattle; Chromatography; Chromatography, High Pressure Liquid; Meat; Mutagens; Quinolines; Quinoxalines

1983
Qualitative and quantitative characterization of mutagens in commercial beef extract.
    Carcinogenesis, 1983, Volume: 4, Issue:7

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Food Analysis; Food Handling; Meat; Mutagens; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet

1983
DNA-binding of IQ, Me-IQ and Me-IQx, strong mutagens found in broiled foods.
    FEBS letters, 1982, Dec-27, Volume: 150, Issue:2

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cooking; DNA; Hot Temperature; Mutagens; Quinolines; Quinoxalines; Spectrophotometry; Thymus Gland

1982
Heterocyclic aromatic amine content of selected beef flavors.
    Mutation research, 1994, Volume: 320, Issue:1-2

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Creatine; Creatinine; Dose-Response Relationship, Drug; Flavoring Agents; Imidazoles; Linear Models; Meat Products; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella typhimurium

1994
Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
    Carcinogenesis, 1995, Volume: 16, Issue:7

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Induction; Erythrocebus patas; Female; Humans; Hydroxylation; Immunoblotting; Isoenzymes; Macaca fascicularis; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Polychlorinated Dibenzodioxins; Quinolines; Quinoxalines; Rats; Rifampin; Species Specificity; Substrate Specificity

1995
Simultaneous expression of human CYP3A7 and N-acetyltransferase in Chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines.
    Archives of biochemistry and biophysics, 1995, Jul-10, Volume: 320, Issue:2

    Topics: Amines; Animals; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Carcinogens; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Gene Expression; Gene Transfer Techniques; Humans; Quinolines; Quinoxalines

1995
Effects of Maillard reaction products on mutagen formation in boiled pork juice.
    Mutagenesis, 1995, Volume: 10, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Maillard Reaction; Meat; Mutagens; Picolines; Pyrazines; Quinolines; Quinoxalines; Swine; Thiophenes

1995
Mutagenic activity of the methyl and phenyl derivatives of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoxaline (IQx) in the Ames test.
    Mutation research, 1993, Volume: 298, Issue:3

    Topics: Animals; Biotransformation; Dose-Response Relationship, Drug; Food; In Vitro Techniques; Isomerism; Microsomes, Liver; Mutagenesis; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Structure-Activity Relationship

1993
Suppressing effects of S phase post-treatment with carbolines on sister-chromatid exchanges induced by mitomycin C in Chinese hamster cells.
    Mutation research, 1993, Volume: 302, Issue:3

    Topics: Animals; Antimutagenic Agents; Carbolines; CHO Cells; Cricetinae; Mitomycin; Mutagens; Quinolines; Quinoxalines; S Phase; Sister Chromatid Exchange

1993
Formation of 2-amino-3-methylimidazo[4,5-f]quinoline- and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-sulfamates by cDNA-expressed mammalian phenol sulfotransferases.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:3

    Topics: Animals; Arylsulfotransferase; Cell Line; Cytosol; DNA, Complementary; Female; Gene Expression; Kinetics; Liver; Male; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Sulfonic Acids

1995
Effect of microwave pretreatment on heterocyclic aromatic amine mutagens/carcinogens in fried beef patties.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:10

    Topics: Amines; Amino Acids; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Cooking; Creatine; Creatinine; Food Irradiation; Glucose; Heterocyclic Compounds; Imidazoles; Meat; Microwaves; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella

1994
Stable expression of human CYP1A2 and N-acetyltransferases in Chinese hamster CHL cells: mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
    Cancer research, 1994, Jul-01, Volume: 54, Issue:13

    Topics: Acetyltransferases; Aflatoxin B1; Animals; Cell Line; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; RNA, Messenger

1994
Effect of cooking time and temperature on the heterocyclic amine content of fried beef patties.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:7

    Topics: Animals; Cattle; Cooking; Hot Temperature; Imidazoles; Meat; Mutagens; Quinolines; Quinoxalines; Time Factors

1994
Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Animals; Dogs; Glucuronates; Imidazoles; In Vitro Techniques; Male; Microsomes, Liver; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1994
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
    Cancer research, 1994, Sep-15, Volume: 54, Issue:18

    Topics: Animals; Colon; Cytosol; DNA; Glutathione; Glutathione Transferase; Humans; Imidazoles; Liver; Quinolines; Quinoxalines; Rats

1994
Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human.
    Carcinogenesis, 1994, Volume: 15, Issue:5

    Topics: Animals; Biotransformation; Callithrix; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Imidazoles; Immunoblotting; Macaca fascicularis; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Species Specificity

1994
In vitro effect of vegetable and fruit juices on the mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:5

    Topics: Animals; Antimutagenic Agents; Beverages; Biotransformation; Fruit; In Vitro Techniques; Male; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Vegetables

1994
Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats.
    Carcinogenesis, 1993, Volume: 14, Issue:10

    Topics: Acetyltransferases; Amino Acyl-tRNA Synthetases; Animals; Colon; Cytosol; DNA; Imidazoles; Kidney; Liver; Macaca fascicularis; Male; Myocardium; Phosphoric Monoester Hydrolases; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Species Specificity; Sulfotransferases

1993
The heterocyclic amines IQ and MeIQx show no promotive effect in a short-term in vivo liver carcinogenesis assay.
    Carcinogenesis, 1993, Volume: 14, Issue:10

    Topics: 2-Acetylaminofluorene; Animals; Carcinogenicity Tests; Diethylnitrosamine; Glutathione Transferase; Hepatectomy; Liver Neoplasms, Experimental; Male; Quinolines; Quinoxalines; Rats; Rats, Wistar

1993
Excretion of food-derived heterocyclic amine carcinogens into breast milk of lactating rats and formation of DNA adducts in the newborn.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: Animal Feed; Animals; Animals, Newborn; Carcinogens; DNA; Female; Imidazoles; Kidney; Lactation; Liver; Mammary Glands, Animal; Milk; Mutagenicity Tests; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Salmonella typhimurium

1993
Metabolism of the food-borne carcinogens 2-amino-3-methylimidazo-[4,5-f]quinoline and 2-amino-3,8- dimethylimidazo[4,5-f]-quinoxaline in the rat as a model for human biomonitoring.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Animals; Biotransformation; Blood Proteins; Carcinogens; Environmental Monitoring; Food Contamination; Humans; In Vitro Techniques; Liver; Male; Protein Binding; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley

1993
32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
    Carcinogenesis, 1993, Volume: 14, Issue:7

    Topics: Animals; Autoradiography; Chromatography, High Pressure Liquid; DNA; DNA Damage; Haplorhini; Imidazoles; Liver; Mutagens; Phosphorus Radioisotopes; Polynucleotides; Quinolines; Quinoxalines

1993
Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
    Carcinogenesis, 1993, Volume: 14, Issue:1

    Topics: Animals; Biotransformation; DNA Damage; Female; Humans; Imidazoles; Macaca fascicularis; Male; Microsomes, Liver; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Species Specificity; Tissue Distribution

1993
In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta mice and c-myc/lacZ double transgenic mice.
    Mutation research, 1996, Sep-23, Volume: 356, Issue:2

    Topics: Animals; Carbolines; DNA Adducts; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Lac Operon; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Microsomes; Mutagenesis; Mutagens; Quinolines; Quinoxalines

1996
Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Animals; Biotransformation; Carcinogens; Cooking; Food; Hot Temperature; Imidazoles; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines

1995
Possible relationship between tissue distribution of DNA adducts and genotoxicity of food-derived heterocyclic amines.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Amines; Animals; Carcinoma, Hepatocellular; Cattle; Cooking; DNA Adducts; Fishes; Heterocyclic Compounds; Hot Temperature; Humans; Liver Neoplasms; Macaca fascicularis; Meat; Mutagens; Poultry; Primates; Quinolines; Quinoxalines; Tissue Distribution

1995
Laparoscopy as a means of monitoring liver tumor induction in nonhuman primates.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Animals; Carcinogens; Equipment Design; Imidazoles; Laparoscopes; Laparoscopy; Liver Neoplasms, Experimental; Macaca mulatta; Palpation; Quinolines; Quinoxalines; Reproducibility of Results; Time Factors

1995
Analysis of foods for heterocyclic aromatic amine carcinogens by solid-phase extraction and high-performance liquid chromatography.
    Journal of chromatography. A, 1997, Feb-28, Volume: 763, Issue:1-2

    Topics: Amines; Animals; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Heterocyclic Compounds; Imidazoles; Meat; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet

1997
Metabolism of food-derived heterocyclic amines in nonhuman primates.
    Mutation research, 1997, May-12, Volume: 376, Issue:1-2

    Topics: Amines; Animals; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; Hydroxylation; Imidazoles; Inactivation, Metabolic; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines

1997
In vivo genotoxicity of heterocyclic amines detected by a modified alkaline single cell gel electrophoresis assay in a multiple organ study in the mouse.
    Mutation research, 1997, Dec-05, Volume: 395, Issue:1

    Topics: Amines; Animals; Brain; Carbolines; DNA Damage; Electrophoresis; Imidazoles; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Mutagens; Quinolines; Quinoxalines; Stomach

1997
Effect of some cooked food mutagens on unscheduled DNA synthesis in cultured precision-cut rat, mouse and human liver slices.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:6

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Autoradiography; Carbolines; Cooking; Culture Techniques; DNA; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Liver; Male; Mice; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Structure-Activity Relationship

1998
Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Animals; Biotransformation; Carbolines; Carcinogens, Environmental; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Food; Hot Temperature; Humans; Imidazoles; Lymphocytes; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Structure-Activity Relationship

1999
Free radical generation from heterocyclic amines by cytochrome b5 reductase in the presence of NADH.
    Cancer letters, 1999, Sep-01, Volume: 143, Issue:2

    Topics: Cytochrome Reductases; Cytochrome-B(5) Reductase; DNA Damage; Free Radicals; Humans; NAD; Quinolines; Quinoxalines; Recombinant Proteins

1999
Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
    Cancer letters, 1999, Sep-01, Volume: 143, Issue:2

    Topics: Animals; Caffeine; Carcinogens; Colonic Neoplasms; Drug Synergism; Imidazoles; Liver Neoplasms, Experimental; Male; Phosphodiesterase Inhibitors; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1999
Carcinogenicity and mutagenicity of heterocyclic amines in transgenic mouse models.
    Cancer letters, 1999, Sep-01, Volume: 143, Issue:2

    Topics: Animals; DNA, Complementary; Genes, myc; Mice; Mice, Transgenic; Mutagenesis; Mutagens; Neoplasms, Experimental; Quinolines; Quinoxalines; Transforming Growth Factor alpha

1999
Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells.
    Mutagenesis, 1999, Volume: 14, Issue:6

    Topics: Amines; Animals; Arylamine N-Acetyltransferase; Carbolines; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Survival; CHO Cells; Cricetinae; Heterocyclic Compounds; Humans; Imidazoles; Liver Neoplasms; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella; Tumor Cells, Cultured

1999
Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay.
    Mutation research, 2001, Aug-22, Volume: 495, Issue:1-2

    Topics: Animals; Antimutagenic Agents; Catechin; Chromatography, High Pressure Liquid; Cooking; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Tea

2001
Reactivity and selectivity of the N-acetyl-Glu-P-1, N-acetyl-Glu-P-2, N-acetyl-MeIQx, and N-acetyl-IQx nitrenium ions: comparison to carbocyclic N-arylnitrenium ions.
    Journal of the American Chemical Society, 2002, Jul-10, Volume: 124, Issue:27

    Topics: Acetylation; Carcinogens; Deoxyguanosine; Imidazoles; Kinetics; Quinolines; Quinoxalines

2002
Induction of micronuclei in V79 cells after combined treatments with heterocyclic aromatic amines.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:10

    Topics: Cell Line; Cell Nucleus; Cytochalasin B; Drug Interactions; Food Analysis; Hot Temperature; Imidazoles; Mutagens; Quinolines; Quinoxalines

2002
Heterocyclic amines in some Swedish cooked foods industrially prepared or from fast food outlets and restaurants.
    Molecular nutrition & food research, 2004, Volume: 48, Issue:4

    Topics: Amines; Animals; Carcinogens; Cooking; Food Analysis; Food Handling; Heterocyclic Compounds; Imidazoles; Meat; Mutagens; Quinolines; Quinoxalines; Restaurants; Sweden

2004
Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Diet; Drug Therapy, Combination; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Quinolines; Quinoxalines

2005
A comparison of genotoxicity between three common heterocyclic amines and acrylamide.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Animals; Dose-Response Relationship, Drug; Erythrocytes; Heterocyclic Compounds; Imidazoles; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Mutagens; Quinolines; Quinoxalines; Structure-Activity Relationship

2005
Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Oct-25, Volume: 825, Issue:2

    Topics: Acetonitriles; Amines; Buffers; Carbolines; Chromatography, Liquid; Formates; Harmine; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Quinolines; Quinoxalines; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2005
Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:3

    Topics: Anticarcinogenic Agents; Antimutagenic Agents; Carbolines; Carcinogens; Food Handling; Heterocyclic Compounds; Hot Temperature; Imidazoles; Lactobacillus; Meat; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines

2008
Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitro.
    European journal of nutrition, 2009, Volume: 48, Issue:7

    Topics: Amines; Aminopyridines; Analysis of Variance; Cells, Cultured; Chromatography, High Pressure Liquid; Colony Count, Microbial; Comet Assay; DNA Damage; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Inactivation, Metabolic; Lacticaseibacillus casei; Mutagens; Probiotics; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet; Time Factors

2009
Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).
    Mutation research, 2010, Feb-03, Volume: 684, Issue:1-2

    Topics: Animals; Arylamine N-Acetyltransferase; Base Sequence; CHO Cells; Cricetinae; Cricetulus; DNA Damage; Humans; Molecular Sequence Data; Mutagenesis; Mutagens; Quinolines; Quinoxalines; Transfection

2010
Selected heterocyclic amines.
    Report on carcinogens : carcinogen profiles, 2004, Volume: 11

    Topics: Amines; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Environmental Exposure; Female; Government Regulation; Guidelines as Topic; Heterocyclic Compounds; Humans; Imidazoles; Macaca fascicularis; Male; Mice; Models, Biological; Quinolines; Quinoxalines; Rats; United States

2004
Formation of heterocyclic amines during cooking of duck meat.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2012, Volume: 29, Issue:11

    Topics: Amines; Animals; Carbolines; China; Chromatography, High Pressure Liquid; Cooking; Ducks; Food Contamination; Harmine; Heterocyclic Compounds; Hot Temperature; Imidazoles; Maillard Reaction; Meat; Microwaves; Mutagens; Quinolines; Quinoxalines; Solid Phase Extraction; Time Factors

2012
Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Biotransformation; Carcinogens; Cell Cycle; Cell Survival; DNA Breaks; DNA Damage; Food Contamination; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Hot Temperature; Humans; Imidazoles; Mutagens; Quinolines; Quinoxalines

2013
Evaluation of maillard reaction variables and their effect on heterocyclic amine formation in chemical model systems.
    Journal of food science, 2015, Volume: 80, Issue:2

    Topics: Carbohydrates; Carcinogens; Chromatography, Reverse-Phase; Creatinine; Hot Temperature; Maillard Reaction; Meat; Models, Chemical; Mutagens; Quinolines; Quinoxalines; Threonine; Water

2015
Selective dopaminergic neurotoxicity of three heterocyclic amine subclasses in primary rat midbrain neurons.
    Neurotoxicology, 2018, Volume: 65

    Topics: Amines; Animals; Carbolines; Dopaminergic Neurons; Dose-Response Relationship, Drug; Harmine; Heterocyclic Compounds, 3-Ring; Mesencephalon; Molecular Structure; Nerve Degeneration; Neurites; Neurons; Primary Cell Culture; Quinolines; Quinoxalines; Rats

2018