Compounds > 2-amino-3-methylimidazo(4,5-f)quinoline
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2-amino-3-methylimidazo(4,5-f)quinoline and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

2-amino-3-methylimidazo(4,5-f)quinoline has been researched along with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine in 91 studies

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.20)18.7374
1990's59 (64.84)18.2507
2000's22 (24.18)29.6817
2010's8 (8.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alldrick, AJ; Coutts, TM; Ho, TA; Rowland, IR1
Ellul, A; O'Neill, I; Ohgaki, H; Turesky, RJ1
Adamson, RH; Schut, HA; Snyderwine, EG; Thorgeirsson, SS; Thorgeirsson, UP1
Felton, JS; Fultz, E; Knize, MG; Roper, M; Shen, NH; Turteltaub, KW1
Ilett, KF; Kadlubar, FF; Minchin, RF; Reeves, PT; Teitel, CH1
Bucci, T; Dooley, KL; Fu, PP; Kadlubar, FF; Von Tungeln, LS1
Gustafsson, JA; Kleman, M; Mason, G; Overvik, E1
Butler, MA; Kadlubar, FF; Lang, NP; Teitel, CH; Turesky, RJ1
Hirose, M; Nagao, M; Ochiai, M; Overvik, E; Sugimura, T1
Adamson, RH; Schut, HA; Snyderwine, EG; Sugimura, T; Takayama, S; Thorgeirsson, SS; Thorgeirsson, UP; Turesky, RJ1
Burgess, WM; Huggett, A; McManus, ME; Quattrochi, LC; Tukey, RH; Veronese, ME1
Felton, JS; Fuscoe, JC; Healy, SK; Shen, NH; Wu, R1
Liu, ZC; Nagao, M; Sugimura, T; Wakabayashi, K; Zhang, XM1
Diachenko, GW; Hargraves, WA; Jackson, LS; Stroup, WH1
Gustafsson, JA; Nord, CE; Orrhage, K; Rafter, J; Sillerström, E1
Endo, H; Schut, HA; Snyderwine, EG2
Davis, CD; Snyderwine, EG1
Fan, L; Schut, HA; Snyderwine, EG1
Davis, CD; Ghoshal, A; Schut, HA; Snyderwine, EG1
Dolbeare, FA; Felton, JS; Fultz, E; Knize, MG1
Canzian, F; Nagao, M; Serikawa, T; Sugimura, T; Ushijima, T; Wakabayashi, K1
Ito, N; Kakiuchi, H; Makino, H; Nagao, M; Onda, M; Sugimura, T; Ushijima, T1
Carroll, KL; Dolbeare, FA; Felton, JS; Knize, MG; Moore, DH1
Chiarelli, MP; Kaderlik, KR; Kadlubar, FF; Lang, NP; Mulder, GJ; Teitel, CH; Turesky, RJ1
Kadlubar, FF; Ketterer, B; Lang, NP; Lin, D; Meyer, DJ1
Davis, CD; Farb, A; Snyderwine, EG; Thorgeirsson, SS; Virmani, R1
Davis, CD; Schut, HA; Snyderwine, EG2
Boobis, AR; Davies, DS; Edwards, RJ; Gant, TW; Murray, BP; Murray, S; Neubert, D; Schulz, T; Thorgeirsson, SS1
Blum, M; Fasshauer, I; Kerdar, RS; Meyer, UA; Probst, M; Wild, D1
Ghoshal, A; Snyderwine, EG1
Davis, CD; Nouso, K; Roller, PP; Schut, HA; Snyderwine, EG1
Imai, K; Ito, N; Kakiuchi, H; Nagao, M; Ochiai, M; Sugimura, T; Ushijima, T; Yachi, A1
Alexander, J; Dragsted, LO; Frandsen, H; Vang, O; Wallin, H1
Coutts, TM; Ellul, A; O'Neill, IK; Randerath, K; Reddy, R; Rowland, IR; Rumney, CJ; Shah, AB1
Adamson, RH; Davis, CD; Schut, HA; Snyderwine, EG; Thorgeirsson, SS; Thorgeirsson, UP1
Felton, JS; Thompson, LH; Wu, RW1
Canzian, F; Imai, K; Kakiuchi, H; Nagao, M; Sugimura, T; Toyota, M; Ushijima, T; Watanabe, M1
Adamson, RH; Buonarati, MH; Snyderwine, EG; Turesky, RJ; Turteltaub, KW1
Adamson, RH; Dalgard, DW; Thorgeirsson, UP1
Adamson, RH; Kristiansen, E; Mortensen, A; Sørensen, IK; Thorgeirsson, SS; van Kreijl, C2
Felton, JS; Hopmans, EC; Knize, MG; Salmon, CP1
Felton, JS; Sorensen, KJ; Thompson, LH; Tucker, JD; Wu, RW1
Cummings, DA; Friesen, MD; Josyula, S; Schut, HA; Smale, MH1
Adamson, RH; Davis, CD; Nagao, M; Sadrieh, N; Schut, HA; Snyderwine, EG; Sugimura, T; Thorgeirsson, SS; Thorgeirsson, UP; Turesky, RJ; Turteltaub, KW1
Darroudi, F; Knasmüller, S; Nagao, M; Parzefall, W; Sanyal, R1
Akasaka, M; Matsusaka, N; Nishidate, E; Ohta, T; Saga, A; Sasaki, YF; Tsuda, S; Watanabe-Akanuma, M1
Dashwood, RH; Nagao, M; Nakagama, H; Sugimura, T; Suzui, M1
Grover, PL; Gusterson, BA; Phillips, DH; Stone, EM; Williams, JA1
Cebula, TA; Felton, JS; Koch, WH; Wu, RW1
Barton, PT; Beamand, JA; Lake, BG; Price, RJ; Tredger, JM1
Catterall, F; Clifford, MN; Copeland, E; Ioannides, C1
Levy, GN; Liu, Y1
Josyula, S; Schut, HA1
Cole, KJ; Grover, PL; Marquardt, H; Martin, FL; Pfau, W; Phillips, DH; Venitt, S1
He, YH; Schut, HA1
Dashwood, RH; Xu, M1
Degawa, M; Konno, Y; Moore, MA; Nakashita, K; Sekine, K; Takasuka, N; Tsuda, H; Uehara, N1
Darroudi, F; Knasmüller, S; Kundi, M; Land, SJ; Parzefall, W; Sanyal, R; Schwab, CE; Wang, CY1
Bol, SA; Constable, A; de Boer, JG; Horlbeck, J; Markovic, J; Turesky, RJ1
Alexander, J; Devanaboyina, US; Eide, TJ; Feng, Y; Fretland, AJ; Hein, DW; Paulsen, JE; Steffensen, IL1
Grover, PL; Hewer, A; Martin, FL; Muir, GH; Phillips, DH; Williams, JA1
Kawamori, T; Ohta, T; Sugimura, T; Uchiya, N; Wakabayashi, K; Watanabe, K1
Amantana, A; Dashwood, RH; Orner, GA; Provost, C; Santana-Rios, G; Wu, SY1
Alexander, J; Andreassen, A; Mikalsen, A; Møllersen, L; Paulsen, JE; Steffensen, IL; Vikse, R1
Frandsen, H; Glatt, HR; Muckel, E1
Antoine, JM; Cassand, P; Cayuela, C; Tavan, E1
Bello, J; Lopez de Cerain, A; Perez, C1
Kimura, S; Knight-Jones, L; Schut, HA; Snyderwine, EG; Yu, M1
Abel, S; Burns, SA; Chiarappa-Zucca, ML; Clifford, AJ; Dingley, KH; Ebeler, SE; Mitchell, AE; Nowell, S; Steinberg, FM; Ubick, EA1
Anderson, D; Jerwood, D; Ruf, AA; Webb, J1
Anderson, D; Ruf, AA; Webb, J1
Brown, K; Chepanoske, CL; Dingley, KH; Turteltaub, KW1
Borgen, E; Skog, K1
Hirose, M; Imazawa, T; Ishii, Y; Kanki, K; Kitamura, Y; Kuroiwa, Y; Nishikawa, A; Umemura, T1
Abramsson-Zetterberg, L; Durling, LJ1
Bianchi, F; Careri, M; Corradini, C; Elviri, L; Mangia, A; Zagnoni, I1
Arquier, D; Canlet, C; Debrauwer, L; Jamin, EL; Rathahao, E; Tulliez, J1
Knasmüller, S; Koller, V; Sontag, G; Stidl, R1
Libudzisz, Z; Nowak, A1
Dobnik, D; Filipič, M; Niderl, MH; Zegura, B1
Anderson, D; Baumgartner, A; Kurzawa-Zegota, M; Najafzadeh, M1
Ioanndes, C; Jalal, JA; Khan, JA; Moselhy, SS1
Karttunen, V; Knudsen, LE; Kummu, M; Mathiesen, L; Mose, T; Myllynen, P; Myöhänen, K; Mørck, TA; Nielsen, JK; Partanen, H; Sieppi, E; Vähäkangas, K1
Liao, GZ; Wang, GY; Xu, XL; Zhang, YJ; Zhou, GH1
Filipič, M; Pezdirc, M; Žegura, B1
Czyżowska, A; Nowak, A; Stańczyk, M1
Ferk, F; Filipič, M; Haas, O; Haslinger, E; Huber, WW; Knasmüller, S; Mai, S; Mikulits, W; Mišík, M; Tomc, J; Waldherr, M; Žegura, B1

Reviews

1 review(s) available for 2-amino-3-methylimidazo(4,5-f)quinoline and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

ArticleYear
Meta-analysis of data from human ex vivo placental perfusion studies on genotoxic and immunotoxic agents within the integrated European project NewGeneris.
    Placenta, 2012, Volume: 33, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Area Under Curve; Central Nervous System Depressants; Ethanol; Female; Humans; Imidazoles; Immunotoxins; Mutagens; Placenta; Pregnancy; Quinolines

2012

Other Studies

90 other study(ies) available for 2-amino-3-methylimidazo(4,5-f)quinoline and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

ArticleYear
Inhibition of the metabolism of mutagens occurring in food by arachidonic acid.
    Mutation research, 1992, Volume: 269, Issue:2

    Topics: Aflatoxin B1; Animals; Antimutagenic Agents; Arachidonic Acid; Biotransformation; DNA Repair; Food; Imidazoles; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium

1992
Entrapment by magnetic microcapsules of the protein pyrolysates IQ, PhIP and Glu-P-1, and alteration of IQ metabolite exposure within the rat gastrointestinal tract by risk-modulating components of the human diet.
    Carcinogenesis, 1992, Volume: 13, Issue:12

    Topics: Adsorption; Animals; Carcinogens; Colorectal Neoplasms; Diet; Digestive System; Humans; Imidazoles; Magnetics; Male; Microspheres; Mutagens; Polyethyleneimine; Quinolines; Rats; Rats, Inbred F344; Risk

1992
Metabolic activation and genotoxicity of heterocyclic arylamines.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7 Suppl

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; DNA; Heterocyclic Compounds; Imidazoles; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Polychlorinated Dibenzodioxins; Quinolines; Quinoxalines; Salmonella

1992
Chemical analysis, prevention, and low-level dosimetry of heterocyclic amines from cooked food.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7 Suppl

    Topics: DNA; Food Analysis; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Meat; Mutagenicity Tests; Quinolines; Quinoxalines

1992
Direct O-acetylation of N-hydroxy arylamines by acetylsalicylic acid to form carcinogen-DNA adducts.
    Carcinogenesis, 1992, Volume: 13, Issue:4

    Topics: Acetylation; Aminobiphenyl Compounds; Aspirin; Carcinogens; DNA; Fluorenes; Imidazoles; Quinolines; Quinoxalines

1992
Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse.
    Cancer letters, 1992, Mar-15, Volume: 62, Issue:3

    Topics: Aminobiphenyl Compounds; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Imidazoles; Liver Neoplasms, Experimental; Male; Mice; Mutagens; Quinolines; Quinoxalines

1992
Effects of the food mutagens MeIQx and PhIP on the expression of cytochrome P450IA proteins in various tissues of male and female rats.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: Animals; Binding, Competitive; Blotting, Northern; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation; Imidazoles; Intestines; Kidney; Liver; Lung; Male; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA

1990
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Topics: Acetylation; Amines; Animals; Biotransformation; Carcinogens; Colon; Cytochrome P-450 Enzyme System; Cytosol; Heterocyclic Compounds; Humans; Imidazoles; Liver; Microsomes, Liver; Mutagens; Oxidation-Reduction; Quinolines; Quinoxalines; Rats

1991
The formation of heart DNA adducts in F344 rat following dietary administration of heterocyclic amines.
    Mutation research, 1991, Volume: 256, Issue:1

    Topics: Administration, Oral; Aging; Amines; Animals; Carbolines; Diet; DNA; DNA Damage; Heart; Imidazoles; Kinetics; Liver; Male; Myocardium; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1991
Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates.
    Princess Takamatsu symposia, 1990, Volume: 21

    Topics: Animals; Chromatography, High Pressure Liquid; DNA; DNA Damage; Dose-Response Relationship, Immunologic; Imidazoles; Liver Neoplasms, Experimental; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines

1990
Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: 2-Acetylaminofluorene; Adolescent; Adult; Aged; Benzo(a)pyrene; Cell Line; Child; Cytochrome P-450 Enzyme System; Food Contamination; Gene Expression; Humans; Hydroxylation; Imidazoles; Microsomes, Liver; Middle Aged; Quinolines; Quinoxalines

1990
Base-change analysis of revertants of the hisD3052 allele in Salmonella typhimurium.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Base Composition; Base Sequence; Benzo(a)pyrene; Carcinogens; Cloning, Molecular; DNA, Bacterial; Food; Histidine; Imidazoles; Molecular Sequence Data; Mutagens; Operon; Quinolines; Salmonella typhimurium

1988
Mutagenic and carcinogenic heterocyclic amines in Chinese cooked foods.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: China; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cooking; Diet; Food Analysis; Heterocyclic Compounds; Imidazoles; Mutagenicity Tests; Mutagens; Mutation; Neoplasms; Quinolines; Quinoxalines

1988
Heterocyclic aromatic amine content of selected beef flavors.
    Mutation research, 1994, Volume: 320, Issue:1-2

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Creatine; Creatinine; Dose-Response Relationship, Drug; Flavoring Agents; Imidazoles; Linear Models; Meat Products; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella typhimurium

1994
Binding of mutagenic heterocyclic amines by intestinal and lactic acid bacteria.
    Mutation research, 1994, Dec-01, Volume: 311, Issue:2

    Topics: Amines; Bifidobacterium; Biotransformation; Carbolines; Chromatography, High Pressure Liquid; Cooking; Food Contamination; Heterocyclic Compounds; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Intestines; Lactobacillus; Meat; Mutagenicity Tests; Mutagens; Quinolines; Regression Analysis

1994
Distribution of the DNA adducts of 2-amino-3-methylimidazo[4,5-f] quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the supF gene as determined by polymerase arrest assay.
    Molecular carcinogenesis, 1995, Volume: 14, Issue:3

    Topics: Autoradiography; Base Sequence; Binding Sites; DNA Adducts; DNA-Directed DNA Polymerase; Genes, Suppressor; Imidazoles; Molecular Sequence Data; Mutagens; Mutation; Quinolines; RNA, Transfer

1995
Protective effect of N-acetylcysteine against heterocyclic amine-induced cardiotoxicity in cultured myocytes and in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1995, Volume: 33, Issue:8

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Carcinogens; Catalase; Cells, Cultured; DNA Adducts; Heart; Hydroxylamines; Imidazoles; L-Lactate Dehydrogenase; Lipid Peroxides; Male; Myocardium; Quinolines; Rats; Rats, Inbred F344; Superoxide Dismutase

1995
Cytotoxicity, DNA adduct formation and DNA repair induced by 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline and 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cultured human mammary epithelial cells.
    Carcinogenesis, 1995, Volume: 16, Issue:4

    Topics: Breast; Carcinogens; Cell Survival; Cells, Cultured; DNA; DNA Adducts; DNA Repair; Epithelium; Formazans; Humans; Imidazoles; Mutagens; Pyridines; Quinolines; Tetrazolium Salts

1995
Metabolic activation of heterocyclic amine food mutagens in the mammary gland of lactating Fischer 344 rats.
    Cancer letters, 1994, Aug-29, Volume: 84, Issue:1

    Topics: Acetyl-CoA C-Acetyltransferase; Amines; Amino Acyl-tRNA Synthetases; Animals; Autoradiography; Biotransformation; DNA; Female; Food; Heterocyclic Compounds; Imidazoles; Lactation; Liver; Mammary Glands, Animal; Microsomes; Mutagenicity Tests; Mutagens; Quinolines; Rats; Rats, Inbred F344

1994
Effect of microwave pretreatment on heterocyclic aromatic amine mutagens/carcinogens in fried beef patties.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:10

    Topics: Amines; Amino Acids; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Cooking; Creatine; Creatinine; Food Irradiation; Glucose; Heterocyclic Compounds; Imidazoles; Meat; Microwaves; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella

1994
Instability of microsatellites in rat colon tumors induced by heterocyclic amines.
    Cancer research, 1994, Dec-15, Volume: 54, Issue:24

    Topics: Animals; Colonic Neoplasms; DNA, Neoplasm; DNA, Satellite; Imidazoles; Male; Mutation; Quinolines; Rats; Rats, Inbred F344

1994
Absence of p53 mutations in rat colon tumors induced by 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole, 2-amino-3-methylimidazo[4,5-f]quinoline, or 2-amino-1-methyl-6-phenylimidazo]4,5-b]pyridine.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Carcinogens; Colonic Neoplasms; Genes, ras; Imidazoles; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Quinolines; Rats; Rats, Inbred F344

1994
Mutagenic specificity of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the supF shuttle vector system.
    Cancer research, 1994, Jul-15, Volume: 54, Issue:14

    Topics: Base Sequence; Cell Line; DNA; Genes, Suppressor; Genetic Vectors; Humans; Imidazoles; Molecular Sequence Data; Mutagens; Mutation; Plasmids; Quinolines

1994
Effect of cooking time and temperature on the heterocyclic amine content of fried beef patties.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:7

    Topics: Animals; Cattle; Cooking; Hot Temperature; Imidazoles; Meat; Mutagens; Quinolines; Quinoxalines; Time Factors

1994
Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Animals; Dogs; Glucuronates; Imidazoles; In Vitro Techniques; Male; Microsomes, Liver; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1994
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
    Cancer research, 1994, Sep-15, Volume: 54, Issue:18

    Topics: Animals; Colon; Cytosol; DNA; Glutathione; Glutathione Transferase; Humans; Imidazoles; Liver; Quinolines; Quinoxalines; Rats

1994
Cardiotoxicity of heterocyclic amine food mutagens in cultured myocytes and in rats.
    Toxicology and applied pharmacology, 1994, Volume: 124, Issue:2

    Topics: Animals; Animals, Newborn; Autoradiography; Body Weight; Carcinogens; Cells, Cultured; DNA, Mitochondrial; Food Contamination; Heart; Imidazoles; L-Lactate Dehydrogenase; Male; Mutagens; Myocardium; Organ Size; Quinolines; Rats; Rats, Inbred F344

1994
Adduction of the heterocyclic amine food mutagens IQ and PhIP to mitochondrial and nuclear DNA in the liver of Fischer-344 rats.
    Carcinogenesis, 1994, Volume: 15, Issue:4

    Topics: Animals; Cell Nucleus; DNA; DNA Damage; DNA, Mitochondrial; Imidazoles; Male; Mitochondria, Liver; Quinolines; Rats; Rats, Inbred F344

1994
Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human.
    Carcinogenesis, 1994, Volume: 15, Issue:5

    Topics: Animals; Biotransformation; Callithrix; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Imidazoles; Immunoblotting; Macaca fascicularis; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Species Specificity

1994
Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats.
    Carcinogenesis, 1993, Volume: 14, Issue:10

    Topics: Acetyltransferases; Amino Acyl-tRNA Synthetases; Animals; Colon; Cytosol; DNA; Imidazoles; Kidney; Liver; Macaca fascicularis; Male; Myocardium; Phosphoric Monoester Hydrolases; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Species Specificity; Sulfotransferases

1993
32P-postlabelling studies on the DNA adducts of the food mutagens/carcinogens IQ and PhIP--adduct formation in a chemical system, and by rat and human metabolism.
    IARC scientific publications, 1993, Issue:124

    Topics: Animals; Arylamine N-Acetyltransferase; Biotransformation; Carcinogens; Cell Line; DNA; DNA Damage; Humans; Imidazoles; In Vitro Techniques; Male; Mutagens; Phosphorus Radioisotopes; Quinolines; Rats; Rats, Inbred F344; Ultraviolet Rays

1993
Excretion of food-derived heterocyclic amine carcinogens into breast milk of lactating rats and formation of DNA adducts in the newborn.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: Animal Feed; Animals; Animals, Newborn; Carcinogens; DNA; Female; Imidazoles; Kidney; Lactation; Liver; Mammary Glands, Animal; Milk; Mutagenicity Tests; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Salmonella typhimurium

1993
32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
    Carcinogenesis, 1993, Volume: 14, Issue:7

    Topics: Animals; Autoradiography; Chromatography, High Pressure Liquid; DNA; DNA Damage; Haplorhini; Imidazoles; Liver; Mutagens; Phosphorus Radioisotopes; Polynucleotides; Quinolines; Quinoxalines

1993
Rare frequency of activation of the Ki-ras gene in rat colon tumors induced by heterocyclic amines: possible alternative mechanisms of human colon carcinogenesis.
    Molecular carcinogenesis, 1993, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Amines; Animals; Base Sequence; Carcinogens; Codon; Colonic Neoplasms; Exons; Gene Expression Regulation, Neoplastic; Genes, ras; Heterocyclic Compounds; Imidazoles; Male; Molecular Sequence Data; Mutation; Quinolines; Rats; Rats, Inbred F344; Transcriptional Activation

1993
Bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine by liver microsomes from three different rat strains.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:6

    Topics: Animals; Aroclors; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Imidazoles; Immunoblotting; Injections, Intraperitoneal; Male; Microsomes, Liver; Mutagens; Oxidoreductases; Protein Binding; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar

1993
Effects of risk-associated human dietary macrocomponents on processes related to carcinogenesis in human-flora-associated (HFA) rats.
    Carcinogenesis, 1993, Volume: 14, Issue:1

    Topics: Animals; Biotransformation; Cecum; Cocarcinogenesis; Cross-Linking Reagents; Dietary Fats; Dietary Fiber; Dietary Proteins; DNA Damage; Drug Compounding; Glucuronidase; Humans; Imidazoles; Intestines; Male; Neoplasms, Experimental; Nitrate Reductase; Nitrate Reductases; Polyethyleneimine; Quinolines; Rats; Rats, Inbred F344

1993
Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
    Carcinogenesis, 1993, Volume: 14, Issue:1

    Topics: Animals; Biotransformation; DNA Damage; Female; Humans; Imidazoles; Macaca fascicularis; Male; Microsomes, Liver; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Species Specificity; Tissue Distribution

1993
Genetically modified Chinese hamster ovary (CHO) cells for studying the genotoxicity of heterocyclic amines from cooked foods.
    Toxicology letters, 1995, Volume: 82-83

    Topics: Animals; Biotransformation; CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Imidazoles; Mutagens; Mutation; Quinolines

1995
Genetic alterations in rat colon tumors induced by heterocyclic amines.
    Cancer, 1996, Apr-15, Volume: 77, Issue:8 Suppl

    Topics: Animals; Base Sequence; Carcinogens; Colonic Neoplasms; DNA Fingerprinting; DNA, Neoplasm; DNA, Satellite; Genes, APC; Imidazoles; Male; Molecular Sequence Data; Mutagens; Mutation; Quinolines; Rats; Rats, Inbred F344

1996
Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Animals; Biotransformation; Carcinogens; Cooking; Food; Hot Temperature; Imidazoles; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines

1995
Laparoscopy as a means of monitoring liver tumor induction in nonhuman primates.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Animals; Carcinogens; Equipment Design; Imidazoles; Laparoscopes; Laparoscopy; Liver Neoplasms, Experimental; Macaca mulatta; Palpation; Quinolines; Quinoxalines; Reproducibility of Results; Time Factors

1995
Short-term carcinogenicity testing of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in E(mu)-pim-1 transgenic mice.
    Carcinogenesis, 1996, Volume: 17, Issue:10

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug; Enhancer Elements, Genetic; Female; Imidazoles; Lymphocytes; Lymphoma; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Quinolines; Sex Factors; Time Factors

1996
Lymphoma induction by heterocyclic amines in E mu-pim-1 transgenic mice.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1997, Volume: 19

    Topics: Animals; Carcinogens; Female; Imidazoles; Lymphoma; Male; Mice; Mice, Transgenic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Quinolines; Sex Factors

1997
Analysis of foods for heterocyclic aromatic amine carcinogens by solid-phase extraction and high-performance liquid chromatography.
    Journal of chromatography. A, 1997, Feb-28, Volume: 763, Issue:1-2

    Topics: Amines; Animals; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Heterocyclic Compounds; Imidazoles; Meat; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet

1997
Differential effect of acetyltransferase expression on the genotoxicity of heterocyclic amines in CHO cells.
    Mutation research, 1997, Apr-24, Volume: 390, Issue:1-2

    Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Cell Survival; CHO Cells; Cricetinae; Humans; Imidazoles; Mutagenesis; Mutagenicity Tests; Mutagens; Mutation; Quinolines; Recombinant Proteins; Salmonella; Transfection

1997
DNA adducts of heterocyclic amines: formation, removal and inhibition by dietary components.
    Mutation research, 1997, May-12, Volume: 376, Issue:1-2

    Topics: Amines; Animals; Antimutagenic Agents; Carcinogens; Diet; DNA Adducts; DNA Repair; Female; Gastric Mucosa; Heterocyclic Compounds; Imidazoles; Indoles; Linoleic Acid; Linoleic Acids; Liver; Male; Mammary Glands, Animal; Mice; Quinolines; Rats; Rats, Inbred F344; Terpenes; Tissue Distribution

1997
Metabolism of food-derived heterocyclic amines in nonhuman primates.
    Mutation research, 1997, May-12, Volume: 376, Issue:1-2

    Topics: Amines; Animals; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; Hydroxylation; Imidazoles; Inactivation, Metabolic; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines

1997
Inhibition of the genotoxic effects of heterocyclic amines in human derived hepatoma cells by dietary bioantimutagens.
    Mutagenesis, 1997, Volume: 12, Issue:4

    Topics: Acrolein; Amines; Antimutagenic Agents; Benzaldehydes; Caffeine; Carbolines; Carcinoma, Hepatocellular; Coumarins; DNA Repair; Heterocyclic Compounds; Humans; Hydrolyzable Tannins; Imidazoles; Micronucleus Tests; Mutagens; Quinolines; Tumor Cells, Cultured

1997
In vivo genotoxicity of heterocyclic amines detected by a modified alkaline single cell gel electrophoresis assay in a multiple organ study in the mouse.
    Mutation research, 1997, Dec-05, Volume: 395, Issue:1

    Topics: Amines; Animals; Brain; Carbolines; DNA Damage; Electrophoresis; Imidazoles; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Mutagens; Quinolines; Quinoxalines; Stomach

1997
High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat.
    Cancer research, 1998, Mar-15, Volume: 58, Issue:6

    Topics: Animals; beta Catenin; Colonic Neoplasms; Cytoskeletal Proteins; DNA, Neoplasm; Imidazoles; Mammary Neoplasms, Experimental; Mutagens; Neoplasms, Experimental; Point Mutation; Quinolines; Rats; Rats, Inbred F344; Trans-Activators

1998
Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.
    Carcinogenesis, 1998, Volume: 19, Issue:5

    Topics: Arylamine N-Acetyltransferase; Biotransformation; Breast; Carcinogens; Cells, Cultured; DNA Adducts; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Imidazoles; Polymorphism, Restriction Fragment Length; Quinolines

1998
Specificity of base substitution mutations induced by the dietary carcinogens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhlP) and 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in Salmonella.
    Environmental and molecular mutagenesis, 1998, Volume: 31, Issue:4

    Topics: Carcinogens; Diet; Imidazoles; Mutagenicity Tests; Mutation; Quinolines; Salmonella

1998
Effect of some cooked food mutagens on unscheduled DNA synthesis in cultured precision-cut rat, mouse and human liver slices.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1998, Volume: 36, Issue:6

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Autoradiography; Carbolines; Cooking; Culture Techniques; DNA; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Liver; Male; Mice; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Structure-Activity Relationship

1998
Contribution of theafulvins to the antimutagenicity of black tea: their mechanism of action.
    Mutagenesis, 1998, Volume: 13, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Benzo(a)pyrene; Carcinogens; Catechin; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Imidazoles; Male; Microsomes, Liver; N-Nitrosopyrrolidine; Nitrosamines; Oxazines; Phenols; Polyphenols; Quinolines; Rats; Rats, Wistar; Tea; Vitamin K

1998
Activation of heterocyclic amines by combinations of prostaglandin H synthase-1 and -2 with N-acetyltransferase 1 and 2.
    Cancer letters, 1998, Nov-13, Volume: 133, Issue:1

    Topics: Acetyltransferases; Animals; Biotransformation; COS Cells; Cytochrome P-450 CYP1A2; Humans; Imidazoles; Isoenzymes; Mutagens; Prostaglandin-Endoperoxide Synthases; Quinolines; Transfection

1998
Effects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 rats.
    Nutrition and cancer, 1998, Volume: 32, Issue:3

    Topics: Acetyl-CoA C-Acetyltransferase; Animals; Anticarcinogenic Agents; Carcinogens; Dietary Fats, Unsaturated; DNA Adducts; Female; Imidazoles; Linoleic Acid; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Quinolines; Rats; Rats, Inbred F344

1998
Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Animals; Biotransformation; Carbolines; Carcinogens, Environmental; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Food; Hot Temperature; Humans; Imidazoles; Lymphocytes; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Structure-Activity Relationship

1999
Inhibition of DNA adduct formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3-methylimidazo[4,5-f]quinoline by dietary indole-3-carbinol in female rats.
    Journal of biochemical and molecular toxicology, 1999, Volume: 13, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Diet; DNA Adducts; Female; Imidazoles; Indoles; Quinolines; Rats; Rats, Sprague-Dawley

1999
Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis.
    Cancer letters, 1999, Sep-01, Volume: 143, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Chlorophyllides; Colon; Colonic Neoplasms; Drug Antagonism; Imidazoles; Indoles; Linoleic Acid; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344

1999
Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
    Cancer letters, 1999, Sep-01, Volume: 143, Issue:2

    Topics: Animals; Caffeine; Carcinogens; Colonic Neoplasms; Drug Synergism; Imidazoles; Liver Neoplasms, Experimental; Male; Phosphodiesterase Inhibitors; Quinolines; Quinoxalines; Rats; Rats, Inbred F344

1999
Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells.
    Mutagenesis, 1999, Volume: 14, Issue:6

    Topics: Amines; Animals; Arylamine N-Acetyltransferase; Carbolines; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Survival; CHO Cells; Cricetinae; Heterocyclic Compounds; Humans; Imidazoles; Liver Neoplasms; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella; Tumor Cells, Cultured

1999
Mutational analysis of the liver, colon and kidney of Big Blue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline.
    Carcinogenesis, 2000, Volume: 21, Issue:1

    Topics: Animals; Animals, Genetically Modified; Bacterial Proteins; Base Sequence; Carcinogens; Colon; DNA Adducts; Escherichia coli Proteins; Imidazoles; Kidney; Lac Repressors; Liver; Male; Mutagens; Mutation; Organ Specificity; Quinolines; Rats; Rats, Inbred F344; Repressor Proteins

2000
DNA adduct levels and intestinal lesions in congenic rapid and slow acetylator syrian hamsters admi food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ).
    Pharmacology & toxicology, 2000, Volume: 86, Issue:6

    Topics: Acetylation; Adenoma; Animals; Animals, Congenic; Arylamine N-Acetyltransferase; Cricetinae; DNA Adducts; DNA, Neoplasm; Female; Food; Imidazoles; Intestinal Neoplasms; Male; Mesocricetus; Mutagens; Precancerous Conditions; Quinolines

2000
Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue.
    Carcinogenesis, 2000, Volume: 21, Issue:9

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; DNA; Gene Expression; Humans; Imidazoles; Male; Organ Culture Techniques; Prostatectomy; Prostatic Hyperplasia; Pyridines; Quinolines; RNA, Messenger

2000
Effects of heterocyclic amines with mammary gland carcinogenic potential on estrogenic response of uterus in ovariectomized rats.
    Cancer letters, 2001, Jan-10, Volume: 162, Issue:1

    Topics: Animals; Carcinogens; Estradiol; Female; Imidazoles; Mammary Neoplasms, Experimental; Ovariectomy; Quinolines; Rats; Rats, Sprague-Dawley; Uterus

2001
Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay.
    Mutation research, 2001, Aug-22, Volume: 495, Issue:1-2

    Topics: Animals; Antimutagenic Agents; Catechin; Chromatography, High Pressure Liquid; Cooking; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Tea

2001
One dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Apc gene.
    Mutation research, 2002, May-27, Volume: 517, Issue:1-2

    Topics: Adenomatous Polyposis Coli Protein; Alleles; Animals; Cloning, Molecular; Female; Imidazoles; Loss of Heterozygosity; Male; Mice; Mice, Inbred C57BL; Mutagens; Mutation; Quinolines

2002
Heterologous expression of human N-acetyltransferases 1 and 2 and sulfotransferase 1A1 in Salmonella typhimurium for mutagenicity testing of heterocyclic amines.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:8

    Topics: Acetyltransferases; Amines; Arylamine N-Acetyltransferase; Arylsulfotransferase; Biotransformation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Heterocyclic Compounds; Humans; Imidazoles; Immunoblotting; Isoenzymes; Mutagenicity Tests; Mutagens; Quinolines; Salmonella typhimurium; Sulfotransferases

2002
Antimutagenic activities of various lactic acid bacteria against food mutagens: heterocyclic amines.
    The Journal of dairy research, 2002, Volume: 69, Issue:2

    Topics: Amines; Animals; Bifidobacterium; Colony Count, Microbial; Fermentation; Food Contamination; Heterocyclic Compounds; Imidazoles; Lactobacillus; Milk; Mutagenicity Tests; Mutagens; Quinolines; Streptococcus

2002
Induction of micronuclei in V79 cells after combined treatments with heterocyclic aromatic amines.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:10

    Topics: Cell Line; Cell Nucleus; Cytochalasin B; Drug Interactions; Food Analysis; Hot Temperature; Imidazoles; Mutagens; Quinolines; Quinoxalines

2002
Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:10

    Topics: Amines; Animals; Colon; Cytochrome P-450 CYP1A2; DNA Adducts; Female; Heterocyclic Compounds; Imidazoles; Kidney; Liver; Mammary Glands, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinolines

2002
Effect of dietary constituents with chemopreventive potential on adduct formation of a low dose of the heterocyclic amines PhIP and IQ and phase II hepatic enzymes.
    Nutrition and cancer, 2003, Volume: 46, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Arylsulfotransferase; Carbon Radioisotopes; Carotenoids; Chlorophyllides; Colon; Diet; Dietary Supplements; DNA Adducts; Genistein; Glucuronosyltransferase; Glutathione Transferase; Imidazoles; Isothiocyanates; Liver; Lycopene; Male; Mutagens; NAD(P)H Dehydrogenase (Quinone); Prostate; Quinolines; Rats; Rats, Inbred F344; Serum Albumin; Tritium

2003
Sensitivity of different thalassaemia genotypes to food mutagens in the Comet assay.
    Teratogenesis, carcinogenesis, and mutagenesis, 2003, Volume: Suppl 2

    Topics: alpha-Thalassemia; beta-Thalassemia; Child, Preschool; Comet Assay; DNA; Drug Tolerance; Female; Food; Gene Deletion; Genotype; Humans; Imidazoles; Iron; Lymphocytes; Male; Mutagens; Quinolines; Reactive Oxygen Species

2003
Modulation by flavonoids of the effects of a food mutagen in different thalassaemia genotypes in the Comet assay.
    Teratogenesis, carcinogenesis, and mutagenesis, 2003, Volume: Suppl 2

    Topics: alpha-Thalassemia; beta-Thalassemia; Child, Preschool; Comet Assay; Female; Flavonoids; Food; Gene Deletion; Genotype; Humans; Imidazoles; Kaempferols; Lymphocytes; Mutagens; Quercetin; Quinolines

2003
Characterization of a peptide adduct formed by N-acetoxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a reactive intermediate of the food carcinogen PhIP.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2004, Volume: 42, Issue:8

    Topics: Carcinogens; Chromatography, High Pressure Liquid; Cysteine; Food Contamination; Humans; Imidazoles; Mass Spectrometry; Models, Biological; Molecular Weight; Peptides; Quinolines; Serum Albumin; Spectrometry, Mass, Electrospray Ionization

2004
Heterocyclic amines in some Swedish cooked foods industrially prepared or from fast food outlets and restaurants.
    Molecular nutrition & food research, 2004, Volume: 48, Issue:4

    Topics: Amines; Animals; Carcinogens; Cooking; Food Analysis; Food Handling; Heterocyclic Compounds; Imidazoles; Meat; Mutagens; Quinolines; Quinoxalines; Restaurants; Sweden

2004
Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Diet; Drug Therapy, Combination; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Quinolines; Quinoxalines

2005
A comparison of genotoxicity between three common heterocyclic amines and acrylamide.
    Mutation research, 2005, Feb-07, Volume: 580, Issue:1-2

    Topics: Acrylamide; Animals; Dose-Response Relationship, Drug; Erythrocytes; Heterocyclic Compounds; Imidazoles; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Mutagens; Quinolines; Quinoxalines; Structure-Activity Relationship

2005
Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Oct-25, Volume: 825, Issue:2

    Topics: Acetonitriles; Amines; Buffers; Carbolines; Chromatography, Liquid; Formates; Harmine; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Quinolines; Quinoxalines; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2005
New insights in the formation of deoxynucleoside adducts with the heterocyclic aromatic amines PhIP and IQ by means of ion trap MSn and accurate mass measurement of fragment ions.
    Journal of the American Society for Mass Spectrometry, 2007, Volume: 18, Issue:12

    Topics: Chromatography, Liquid; Deoxyguanosine; Imidazoles; Mass Spectrometry; Molecular Weight; Quinolines

2007
Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:3

    Topics: Anticarcinogenic Agents; Antimutagenic Agents; Carbolines; Carcinogens; Food Handling; Heterocyclic Compounds; Hot Temperature; Imidazoles; Lactobacillus; Meat; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines

2008
Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitro.
    European journal of nutrition, 2009, Volume: 48, Issue:7

    Topics: Amines; Aminopyridines; Analysis of Variance; Cells, Cultured; Chromatography, High Pressure Liquid; Colony Count, Microbial; Comet Assay; DNA Damage; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Inactivation, Metabolic; Lacticaseibacillus casei; Mutagens; Probiotics; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet; Time Factors

2009
Selected heterocyclic amines.
    Report on carcinogens : carcinogen profiles, 2004, Volume: 11

    Topics: Amines; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Environmental Exposure; Female; Government Regulation; Guidelines as Topic; Heterocyclic Compounds; Humans; Imidazoles; Macaca fascicularis; Male; Mice; Models, Biological; Quinolines; Quinoxalines; Rats; United States

2004
Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells.
    Environmental toxicology and pharmacology, 2011, Volume: 32, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antioxidants; Benzo(a)pyrene; Cytoprotection; DNA Damage; Free Radical Scavengers; Hep G2 Cells; Humans; Imidazoles; Microbial Sensitivity Tests; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Quinolines; Rosmarinus; Salmonella typhimurium; tert-Butylhydroperoxide

2011
The protective effect of the flavonoids on food-mutagen-induced DNA damage in peripheral blood lymphocytes from colon cancer patients.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cells, Cultured; Colonic Neoplasms; DNA Damage; Dose-Response Relationship, Drug; Female; Flavonoids; Food Analysis; Humans; Imidazoles; Lymphocytes; Male; Middle Aged; Mutagens; Quercetin; Quinolines; Rutin; Young Adult

2012
Impact of aqueous doash extract on urinary mutagenicity in rats exposed to heterocyclic amines.
    Toxicology and industrial health, 2013, Volume: 29, Issue:2

    Topics: Animals; Antimutagenic Agents; Body Weight; DNA Damage; Imidazoles; Male; Medicine, Traditional; Mutagenicity Tests; Mutagens; Origanum; Plant Extracts; Quinolines; Rats; Rats, Wistar; Ribosomal Protein S9; Ribosomal Proteins; Salmonella typhimurium

2013
Formation of heterocyclic amines during cooking of duck meat.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2012, Volume: 29, Issue:11

    Topics: Amines; Animals; Carbolines; China; Chromatography, High Pressure Liquid; Cooking; Ducks; Food Contamination; Harmine; Heterocyclic Compounds; Hot Temperature; Imidazoles; Maillard Reaction; Meat; Microwaves; Mutagens; Quinolines; Quinoxalines; Solid Phase Extraction; Time Factors

2012
Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59

    Topics: Biotransformation; Carcinogens; Cell Cycle; Cell Survival; DNA Breaks; DNA Damage; Food Contamination; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Hot Temperature; Humans; Imidazoles; Mutagens; Quinolines; Quinoxalines

2013
Protective activity of probiotic bacteria against 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine (PhIP) - an in vitro study.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2015, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminopyridines; Cell Survival; Child; Child, Preschool; Feces; Gastrointestinal Microbiome; Humans; Imidazoles; Infant; Lactobacillus; Probiotics; Quinolines; Young Adult

2015
Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?
    Archives of toxicology, 2018, Volume: 92, Issue:2

    Topics: Aflatoxin B1; Benzo(a)pyrene; Cell Line, Tumor; Dimethylnitrosamine; Humans; Hydrogen Peroxide; Imidazoles; Inactivation, Metabolic; Liver; Mutagenicity Tests; Mutagens; Quinolines; Reactive Oxygen Species; Tumor Suppressor Protein p53

2018