Compounds > 2-amino-3-methyl-9h-pyrido(2,3-b)indole
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2-amino-3-methyl-9h-pyrido(2,3-b)indole and 2-amino-9h-pyrido(2,3-b)indole

2-amino-3-methyl-9h-pyrido(2,3-b)indole has been researched along with 2-amino-9h-pyrido(2,3-b)indole in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Furukawa, F; Hasegawa, R; Hayashi, Y; Miyakawa, Y; Sato, H; Takahashi, M; Toyoda, K1
Hasegawa, H; Kato, T; Ohgaki, H; Sato, S; Suenaga, M; Sugimura, T; Takayama, S; Ubukata, M1
Matsumoto, T; Yoshida, D1
Matsumoto, T; Tomita, H; Yoshida, D1
Cole, KJ; Grover, PL; Marquardt, H; Martin, FL; Pfau, W; Phillips, DH; Venitt, S1
Frandsen, H; Frederiksen, H2
Frandsen, H; Frederiksen, H; Pfau, W1
Frederiksen, H1
Afonso, AM; Ayala, JH; González, V; Martín-Calero, A; Tejral, G1
Blount, BC; Chang, CM; deCastro, BR; Li, Y; Pine, BN; Sosnoff, CS; Wang, L; Xia, B; Xia, Y; Zhang, L1

Reviews

1 review(s) available for 2-amino-3-methyl-9h-pyrido(2,3-b)indole and 2-amino-9h-pyrido(2,3-b)indole

ArticleYear
Two food-borne heterocyclic amines: metabolism and DNA adduct formation of amino-alpha-carbolines.
    Molecular nutrition & food research, 2005, Volume: 49, Issue:3

    Topics: Amines; Animals; Carbolines; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; Food Analysis; Heterocyclic Compounds; Hot Temperature; Humans; Meat; Microsomes, Liver; Mutagens; Rats

2005

Other Studies

10 other study(ies) available for 2-amino-3-methyl-9h-pyrido(2,3-b)indole and 2-amino-9h-pyrido(2,3-b)indole

ArticleYear
Initiating activity in a two-stage mouse skin model of nine mutagenic pyrolysates of amino acids, soybean globulin and proteinaceous food.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Animals; Carbolines; Female; Imidazoles; Mice; Mutagens; Quinolines; Skin Neoplasms; Tetradecanoylphorbol Acetate

1987
Carcinogenicity in mice and rats of heterocyclic amines in cooked foods.
    Environmental health perspectives, 1986, Volume: 67

    Topics: Animals; Carbolines; Carcinogens; Female; Food Contamination; Heterocyclic Compounds; Hot Temperature; Imidazoles; Male; Mice; Neoplasms, Experimental; Quinolines; Rats

1986
Amino-alpha-carbolines as mutagenic agents in cigarette smoke condensate.
    Cancer letters, 1980, Volume: 10, Issue:2

    Topics: Carbolines; Dose-Response Relationship, Drug; Indoles; Mass Spectrometry; Mutagenicity Tests; Mutagens; Nicotiana; Plants, Toxic; Salmonella typhimurium; Smoke; Spectrometry, X-Ray Emission

1980
Determination of mutagens, amino-alpha-carbolines in grilled foods and cigarette smoke condensate.
    Cancer letters, 1981, Volume: 12, Issue:1-2

    Topics: Animals; Carbolines; Cattle; Chromatography, High Pressure Liquid; Cooking; Food Analysis; Hot Temperature; Indoles; Meat; Mutagens; Smoking

1981
Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Animals; Biotransformation; Carbolines; Carcinogens, Environmental; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Food; Hot Temperature; Humans; Imidazoles; Lymphocytes; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Structure-Activity Relationship

1999
In vitro metabolism of two heterocyclic amines, 2-amino-9H-pyrido[2,3-b]indole (A(alpha)C) and 2-amino-3-methyl-9H-pyridol2,3-b]indole (MeA(alpha)C) in human and rat hepatic microsomes.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:3

    Topics: Animals; Carbolines; Chromatography, High Pressure Liquid; Humans; Male; Microsomes, Liver; Molecular Structure; Molecular Weight; Polychlorinated Biphenyls; Rats; Rats, Wistar; Spectrum Analysis; Tritium

2002
Impact of five cytochrome p450 enzymes on the metabolism of two heterocyclic aromatic amines, 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC).
    Pharmacology & toxicology, 2003, Volume: 92, Issue:5

    Topics: Animals; Carbolines; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Mutagens; Rats; Time Factors

2003
Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC) and 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and identification of DNA adducts in organs from rats dosed with MeAalphaC.
    Carcinogenesis, 2004, Volume: 25, Issue:8

    Topics: Acetic Anhydrides; Animals; Carbolines; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA; DNA Adducts; Ions; Liver; Male; Models, Chemical; Mutagens; Rats; Rats, Wistar; Temperature; Thymus Gland; Time Factors; Ultraviolet Rays

2004
Suitability of ionic liquids as mobile-phase additives in HPLC with fluorescence and UV detection for the determination of heterocyclic aromatic amines.
    Journal of separation science, 2010, Volume: 33, Issue:2

    Topics: Amines; Carbolines; Chromatography, High Pressure Liquid; Heterocyclic Compounds; Imidazoles; Ionic Liquids; Polycyclic Aromatic Hydrocarbons; Silanes; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2010
Evaluation of Tobacco Smoke and Diet as Sources of Exposure to Two Heterocyclic Aromatic Amines for the U.S. Population: NHANES 2013-2014.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2020, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Carbolines; Carcinogens; Chromatography, High Pressure Liquid; Cooking; Cross-Sectional Studies; Female; Hot Temperature; Humans; Male; Middle Aged; Nicotiana; Non-Smokers; Nutrition Surveys; Red Meat; Self Report; Smokers; Tandem Mass Spectrometry; Tobacco Smoke Pollution; United States; Young Adult

2020