Compounds > 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
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2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline and deoxyguanosine

2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline has been researched along with deoxyguanosine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's6 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kristiansen, E; Meyer, O; Thorup, I1
Kawanishi, S; Kobayashi, M; Murata, M1
Boobis, AR; Bowey, EA; Edwards, AJ; Gooderham, NJ; Gray, S; Lake, BG; Murray, S; Springall, C; Williamson, G1
Fukushima, S; Nakae, D; Nishkawa, T; Ogawa, M; Otani, S; Totsuka, Y; Wakabayashi, K; Wanibuchi, H; Yano, Y1
Fukushima, S; Ichihara, T; Morimura, K; Nakae, D; Totsuka, Y; Wanibuchi, H; Wei, M1
Doi, K; Fukushima, S; Karim, MR; Kinoshita, A; Morimura, K; Wanibuchi, H; Wei, M1
Fukushima, S; Kang, JS; Mori, S; Morimura, K; Murai, T; Totsuka, Y; Wanibuchi, H1
Bendaly, J; Hein, DW; Metry, KJ; Neale, JR; Pierce, WM; Smith, NB1

Other Studies

8 other study(ies) available for 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline and deoxyguanosine

ArticleYear
The ability of two cooked food mutagens to induce aberrant crypt foci in mice.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1997, Volume: 6, Issue:1

    Topics: Analysis of Variance; Animals; Azoxymethane; Carcinogens; Colon; Cooking; Deoxyguanosine; Diet; Disease Models, Animal; Female; Food, Fortified; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Mice; Mice, Inbred C57BL; Mutagens; Quinoxalines; Reference Values; Weight Gain

1997
Mechanism of oxidative DNA damage induced by a heterocyclic amine, 2-amino-3,8-dimethylimidazo[4,5f]quinoxaline.
    Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Amines; Animals; Catalase; Cattle; Chelating Agents; Chromatography, High Pressure Liquid; Copper; Cytosine; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Genes, p53; Genes, ras; Hydrogen Peroxide; Models, Chemical; NAD; Oxidation-Reduction; Phenanthrolines; Quinoxalines; Spectrum Analysis; Thymine

1999
Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man.
    Carcinogenesis, 2001, Volume: 22, Issue:9

    Topics: Adult; Biomarkers; Biotransformation; Brassica; Caffeine; Carcinogens; Cytochrome P-450 CYP1A2; Deoxyguanosine; DNA; Humans; Imidazoles; Lymphocytes; Male; Meat; Middle Aged; Quinoxalines

2001
Post-initiation inhibition of MeIQx hepatocarcinogenesis in rats by cysteine.
    Osaka city medical journal, 2003, Volume: 49, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cysteine; Deoxyguanosine; DNA; Genes, p53; Insulin-Like Growth Factor I; Liver Neoplasms, Experimental; Male; Nucleolus Organizer Region; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

2003
Induction of DNA-adducts and increase of 8-hydroxy-2-deoxyguanosine, but no development of preneoplastic lesions in offspring liver with transplacental and trans-breast milk exposure to 2-amino-3,8-dimethylimidazo [4,5-f ]quinoxaline (MeIQx) in rats.
    Cancer science, 2004, Volume: 95, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cell Proliferation; Colon; Colonic Neoplasms; Deoxyguanosine; Diet; DNA Adducts; Female; Glutathione Transferase; Humans; Lactation; Liver; Liver Neoplasms, Experimental; Male; Milk, Human; Placenta; Precancerous Conditions; Pregnancy; Quinoxalines; Rats; Rats, Inbred F344

2004
Existence of no hepatocarcinogenic effect levels of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline with or without coadministration with ethanol.
    Toxicologic pathology, 2006, Volume: 34, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogens; Central Nervous System Depressants; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Ethanol; Glutathione S-Transferase pi; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; No-Observed-Adverse-Effect Level; Proliferating Cell Nuclear Antigen; Quinoxalines; Rats; Rats, Inbred F344

2006
Evidence of a threshold-effect for 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline liver carcinogenicity in F344/DuCrj rats.
    Toxicologic pathology, 2008, Volume: 36, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenoma, Liver Cell; Administration, Oral; Animal Feed; Animals; Carcinogens; Carcinoma, Hepatocellular; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Glutathione Transferase; Liver; Liver Neoplasms; Longevity; Male; No-Observed-Adverse-Effect Level; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

2008
Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:11

    Topics: Acetylation; Animals; Animals, Congenic; Arylamine N-Acetyltransferase; Carcinogens; Colonic Neoplasms; Deoxyguanosine; DNA Adducts; Female; Gene Targeting; Genetic Predisposition to Disease; Imidazoles; Liver Neoplasms; Mutagens; Polymorphism, Genetic; Quinoxalines; Rats; Rats, Inbred F344; Rats, Inbred WKY; Time Factors

2009