2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline has been researched along with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine in 146 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.37) | 18.7374 |
| 1990's | 71 (48.63) | 18.2507 |
| 2000's | 38 (26.03) | 29.6817 |
| 2010's | 34 (23.29) | 24.3611 |
| 2020's | 1 (0.68) | 2.80 |
| Authors | Studies |
|---|---|
| Alldrick, AJ; Coutts, TM; Ho, TA; Rowland, IR | 1 |
| Boobis, AR; Davies, DS; Gooderham, NJ; Knize, MG; Lynch, AM; Murray, S | 1 |
| Adamson, RH; Schut, HA; Snyderwine, EG; Thorgeirsson, SS; Thorgeirsson, UP | 1 |
| Felton, JS; Fultz, E; Knize, MG; Roper, M; Shen, NH; Turteltaub, KW | 1 |
| Ilett, KF; Kadlubar, FF; Minchin, RF; Reeves, PT; Teitel, CH | 1 |
| Bucci, T; Dooley, KL; Fu, PP; Kadlubar, FF; Von Tungeln, LS | 1 |
| Gustafsson, JA; Kleman, M; Mason, G; Overvik, E | 1 |
| Hirose, M; Itoh, H; Nagao, M; Sugimura, T; Ushiyama, H; Wakabayashi, K | 1 |
| Butler, MA; Kadlubar, FF; Lang, NP; Teitel, CH; Turesky, RJ | 1 |
| Hirose, M; Nagao, M; Ochiai, M; Overvik, E; Sugimura, T | 1 |
| Buonarati, MH; Davis, JC; Felton, JS; Gledhill, BL; Turteltaub, KW; Vogel, JS | 1 |
| Adamson, RH; Schut, HA; Snyderwine, EG; Sugimura, T; Takayama, S; Thorgeirsson, SS; Thorgeirsson, UP; Turesky, RJ | 1 |
| Burgess, WM; Huggett, A; McManus, ME; Quattrochi, LC; Tukey, RH; Veronese, ME | 1 |
| Blanck, A; Gustafsson, JA; Kleman, M; Overvik, E | 1 |
| Liu, ZC; Nagao, M; Sugimura, T; Wakabayashi, K; Zhang, XM | 1 |
| Diachenko, GW; Hargraves, WA; Jackson, LS; Stroup, WH | 1 |
| Brown, ED; Cunningham, PL; Felton, JS; Knize, MG; Levander, OA; Rothman, N; Salmon, CP; Sinha, R | 1 |
| Brown, ED; Caporaso, NE; Hoover, RN; Kadlubar, FF; Knize, MG; Lang, NP; Levander, OA; Mark, SD; Rothman, N; Sinha, R | 1 |
| Dolbeare, FA; Felton, JS; Fultz, E; Knize, MG | 1 |
| Carroll, KL; Dolbeare, FA; Felton, JS; Knize, MG; Moore, DH | 1 |
| Jägerstad, M; Johansson, MA | 1 |
| Chiarelli, MP; Kaderlik, KR; Kadlubar, FF; Lang, NP; Mulder, GJ; Teitel, CH; Turesky, RJ | 1 |
| Nagao, M; Oguri, A; Wakabayashi, K; Weisburger, JH | 1 |
| Kadlubar, FF; Ketterer, B; Lang, NP; Lin, D; Meyer, DJ | 1 |
| Boobis, AR; Brooks, RA; Edwards, RJ; Gooderham, NJ; Howard, LA; Winton, DJ; Zhao, K | 1 |
| Boobis, AR; Davies, DS; Edwards, RJ; Gant, TW; Murray, BP; Murray, S; Neubert, D; Schulz, T; Thorgeirsson, SS | 1 |
| Davis, CD; Schut, HA; Snyderwine, EG | 1 |
| Ghoshal, A; Snyderwine, EG | 1 |
| Fay, LB; Gross, GA; Skipper, PL; Stillwell, WG; Tannenbaum, SR; Turesky, RJ | 1 |
| Shubik, P | 1 |
| Boobis, AR; Davies, DS; de la Torre, R; Farré, M; Gooderham, NJ; Lynch, AM; Murray, S; Segura, J; Solans, A | 1 |
| Hirose, M; Kim, SB; Nagao, M; Nukaya, H; Ochiai, M; Sugimura, T; Takahashi, M; Ushiyama, H; Wakabayashi, K | 1 |
| Djanegara, T; Hwang, M; Vanderlaan, M | 1 |
| Davis, CD; Nouso, K; Roller, PP; Schut, HA; Snyderwine, EG | 1 |
| Gooderham, MJ; Knize, MG; Lynch, AM; Murray, S | 1 |
| Gustafsson, JA; Hellmold, H; Overvik, E; Strömstedt, M | 1 |
| Adamson, RH; Davis, CD; Schut, HA; Snyderwine, EG; Thorgeirsson, SS; Thorgeirsson, UP | 1 |
| Fukutome, K; Sugimura, T; Tada, A; Takahashi, M; Takahashi, S; Totsuka, Y; Wakabayashi, K | 1 |
| Boobis, AR; Davies, DS; de la Torre, R; Gooderham, NJ; Lynch, A; Murray, S; Segura, J | 2 |
| Boobis, AR; Davies, DS; Edwards, RJ; Gooderham, NJ; Lynch, AM; Murray, S; Yadollahi-Farsani, M | 1 |
| Adamson, RH; Sugimura, T; Thorgeirsson, UP | 1 |
| Nagao, M; Sugimura, T; Totsuka, Y; Toyota, M; Ushijima, T; Wakabayashi, K | 1 |
| Bhadresa, S; Boobis, AR; Bratt, C; Crosbie, SJ; Davies, DS; Edwards, RJ; Gooderham, NJ; Lynch, AM; Murray, BP; Murray, S; Rich, KJ; Yadollahi-Farsani, M; Zhao, K | 1 |
| Boobis, AR; Gooderham, NJ; Lynch, AM; Murray, S | 1 |
| Adamson, RH; Buonarati, MH; Snyderwine, EG; Turesky, RJ; Turteltaub, KW | 1 |
| Felton, JS; Frantz, C; McManus, M; Turteltaub, KW; Vogel, JS | 1 |
| Branting, C; Gustafsson, JA; Hellmold, H; Overvik, E | 1 |
| Boobis, AR; Davies, DS; Edwards, RJ; Gooderham, NJ; Lynch, AM; Murray, BP; Murray, S; Rich, KJ; Zhao, K | 1 |
| Adamson, RH; Dalgard, DW; Farb, A; Snyderwine, EG; Sugimura, T; Takayama, S; Thorgeirsson, SS; Thorgeirsson, UP; Virmani, R | 1 |
| Adamson, RH; Dalgard, DW; Thorgeirsson, UP | 1 |
| Inoue, R; Kakiuchi, H; Makino, H; Nagao, M; Sugimura, T; Ushijima, T | 1 |
| Heiniö, RL; Latva-Kala, KJ; Tikkanen, LM | 1 |
| Sugimura, T | 1 |
| Felton, JS; Hopmans, EC; Knize, MG; Salmon, CP | 1 |
| Felton, JS; Knize, MG; Salmon, CP | 2 |
| Kidd, LC; Sinha, R; Stillwell, WG; Tannenbaum, SR; Wishnok, JS | 1 |
| Ohe, T | 1 |
| Augustsson, K; Jägerstad, M; Skog, K; Steineck, G | 1 |
| Akasaka, M; Matsusaka, N; Nishidate, E; Ohta, T; Saga, A; Sasaki, YF; Tsuda, S; Watanabe-Akanuma, M | 1 |
| Barton, PT; Beamand, JA; Lake, BG; Price, RJ; Tredger, JM | 1 |
| Oguri, A; Suda, M; Sugimura, T; Totsuka, Y; Wakabayashi, K | 1 |
| Constable, A; Guengerich, FP; Markovic, J; Martin, MV; Richoz, J; Turesky, RJ; Varga, N | 1 |
| Dingley, KH; Turteltaub, KW | 1 |
| Cole, KJ; Grover, PL; Marquardt, H; Martin, FL; Pfau, W; Phillips, DH; Venitt, S | 1 |
| Henderson, BE; Kidd, LC; Ross, RK; Skipper, PL; Stillwell, WG; Tannenbaum, SR; Wishnok, JS; Yu, MC | 1 |
| Furukawa, F; Hirose, M; Kasahara, K; Miyauchi, M; Nakamura, H; Nishikawa, A; Takahashi, M | 1 |
| Fujita, K; Iwata, H; Kamataki, T; Kushida, H; Nohmi, T; Suzuki, A; Watanabe, M | 1 |
| Curtis, KD; Dingley, KH; Felton, JS; Garner, RC; Lang, NP; Malfatti, MA; Turesky, RJ; Turteltaub, KW | 1 |
| Alexander, DJ; Coxhead, JM; Cupid, BC; Dingley, KH; Garner, RC; Kutschera, W; Leveson, SH; Lightfoot, TJ; Mauthe, RJ; Priller, A; Rom, W; Russell, D; Steier, P; Turteltaub, KW | 1 |
| Rothman, N; Sinha, R | 1 |
| Degawa, M; Konno, Y; Moore, MA; Nakashita, K; Sekine, K; Takasuka, N; Tsuda, H; Uehara, N | 1 |
| Darroudi, F; Knasmüller, S; Kundi, M; Land, SJ; Parzefall, W; Sanyal, R; Schwab, CE; Wang, CY | 1 |
| Anton-Culver, H; Butler, J; Delfino, RJ; Gim, JS; Liao, SY; Lin, HJ; Ma, HL; Sinha, R; Smith, C; West, J; White, E | 1 |
| Alavanja, MC; Brownson, RC; Curtin, J; Kulldorff, M; Sinha, R; Swanson, CA | 1 |
| Amantana, A; Dashwood, RH; Orner, GA; Provost, C; Santana-Rios, G; Wu, SY | 1 |
| Boobis, AR; Bowey, EA; Edwards, AJ; Gooderham, NJ; Gray, S; Lake, BG; Murray, S; Springall, C; Williamson, G | 1 |
| Jägerstad, M; Lundström, K; Olsson, V; Skog, K; Solyakov, A | 1 |
| Alexander, J; Becher, G; Frandsen, H; Hegstad, S; Ingebrigtsen, K; Paulsen, JE; Reistad, R | 1 |
| Ambrosone, CB; Coles, B; Kadlubar, FF; Lang, NP; Luke Ratnasinghe, D; MacLeod, S; Nowell, S; Sinha, R; Stotts, C | 1 |
| Guengerich, FP; Guillouzo, A; Langouët, S; Turesky, RJ | 1 |
| Sinha, R | 1 |
| Hanaoka, T; Kataoka, H; Kobayashi, M; Nishioka, S; Tsugane, S | 1 |
| Furukawa, F; Hirose, M; Kobayashi, Y; Koide, A; Mori, Y; Nishikawa, A | 1 |
| Gray, JI; Shin, HS; Strasburg, GM | 1 |
| Persson, E; Sjöholm, I; Skog, K | 1 |
| Boyce, A; Doehmer, J; Gooderham, NJ | 1 |
| Kohno, H; Sugie, S; Suzuki, R; Takahashi, M; Tanaka, T; Wakabayashi, K | 1 |
| Borgen, E; Skog, K | 1 |
| Hirose, M; Imazawa, T; Ishii, Y; Kanki, K; Kitamura, Y; Kuroiwa, Y; Nishikawa, A; Umemura, T | 1 |
| Abramsson-Zetterberg, L; Durling, LJ | 1 |
| Gehring, T; Gooderham, NJ; Holland, RD; Lake, BG; Taylor, J; Turesky, RJ | 1 |
| Bianchi, F; Careri, M; Corradini, C; Elviri, L; Mangia, A; Zagnoni, I | 1 |
| Cross, AJ; Hayes, RB; Kulldorff, M; Peters, U; Pinsky, PF; Rothman, N; Sinha, R; Weissfeld, JL | 1 |
| Andriole, GL; Cross, AJ; Hayes, RB; Kirsh, VA; Peters, U; Reding, D; Sinha, R | 1 |
| Bennett, LM; Bennion, BJ; Cosman, M; Felton, JS; Knize, MG; Kulp, KS; Lightstone, FC; Montgomery, JL | 1 |
| Doll, MA; Fretland, AJ; Hein, DW | 1 |
| Busquets, R; Galceran, MT; Puignou, L; Toribio, F | 1 |
| Chen, F; Cheng, KW; Wang, M | 1 |
| Peterson, S; Turesky, RJ; Wang, R; Yu, MC; Yuan, JM | 1 |
| Chen, F; Cheng, KW; Peng, X; Simon, JE; Wang, M; Wu, Q; Zheng, ZP | 1 |
| Knasmüller, S; Koller, V; Sontag, G; Stidl, R | 1 |
| Enokizono, J; Kusuhara, H; Ose, A; Schinkel, AH; Sugiyama, Y | 1 |
| Ban, H; Hirata, A; Imai, T; Masegi, T; Nishigaki, R; Sakai, H; Takasu, S; Tatematsu, M; Totsuka, Y; Tsukamoto, T; Wakabayashi, K; Yanai, T | 1 |
| Gibis, M; Jautz, U; Morlock, GE | 1 |
| Ferreira, IM; Melo, A; Petisca, C; Pinho, O; Viegas, O | 1 |
| Bagnardi, V; Bertazzi, PA; Caporaso, NE; Consonni, D; Cross, AJ; Lam, TK; Landi, MT; Randi, G; Sinha, R; Subar, AF | 1 |
| Libudzisz, Z; Nowak, A | 1 |
| Busquets, R; Frandsen, H; Galceran, MT; Jönsson, JA; Puignou, L; Skog, K | 1 |
| Gooderham, NJ; Gu, D; Kadlubar, FF; Lake, BG; Lemaster, D; McNaughton, L; Turesky, RJ | 1 |
| Cross, AJ; Ferrucci, LM; Graubard, BI; Hollenbeck, AR; Park, Y; Risch, A; Schatzkin, A; Sinha, R; Ward, MH | 1 |
| Aninat, C; Anthérieu, S; Dumont, J; Guguen-Guillouzo, C; Guillouzo, A; Jossé, R; Lambert, C; Le Hegarat, L; Robin, MA | 1 |
| Cho, E; Giovannucci, E; Holmes, MD; Sinha, R; Willett, W; Wu, K | 1 |
| Puangsombat, K; Smith, JS | 1 |
| Haza, AI; Morales, P | 1 |
| Anthérieu, S; Dumont, J; Guillouzo, A; Jossé, R; Lambert, C; Laurent, V; Loyer, P; Robin, MA | 1 |
| Caberto, C; Chanock, S; Decker, R; Le Marchand, L; Saltzman, B; Vogt, TM; Wang, H; Wilkens, LR; Yamamoto, JF; Yokochi, L | 1 |
| Gu, D; Kadlubar, FF; Raymundo, MM; Turesky, RJ | 1 |
| Arimoto-Kobayashi, S; Hatano, T; Ishida, R; Kamiya, T; Okamoto, G; Yuhara, Y; Zhang, X | 1 |
| Jirapakkul, W; Puangsombat, K; Smith, JS | 1 |
| Peng, Z; Shao, B; Wan, K; Wu, G; Yang, H; Yao, Y | 1 |
| Gadgil, P; Houser, TA; Hunt, MC; Puangsombat, K; Smith, JS | 1 |
| Ferreira, IM; Filipič, M; Novak, M; Pezdric, M; Pinho, O; Viegas, O; Zegura, B | 1 |
| Feinstein, Y; Friedman, M; Havens, CM; Ravishankar, S; Rounds, L | 1 |
| Liao, GZ; Wang, GY; Xu, XL; Zhang, YJ; Zhou, GH | 1 |
| Ding, Z; Guo, D; Li, F; Su, M; Wang, M; Yao, J | 1 |
| Fujii-Kuriyama, Y; Goto, M; Iijma, K; Ishizaka, Y; Kano, S; Matsunaga, A; Nakagama, H; Ochiai, M; Okamura, T; Okudaira, N; Tamura, M | 1 |
| Cross, AJ; Harper, G; Hartman, TJ; Laio, J; Lazarus, P; Lesko, SM; Miller, PE; Muscat, JE; Sinha, R; Zhu, J | 1 |
| Gibis, M; Weiss, J | 2 |
| Blasiak, J; Chojnacki, C; Chojnacki, J; Czubatka, A; Klupinska, G; Poplawski, T | 1 |
| Filipič, M; Pezdirc, M; Žegura, B | 1 |
| Mei, J; Wang, S; Yu, C; Zhang, Y | 1 |
| Szterk, A | 1 |
| Aalhus, JL; Dugan, ME; Juárez, M; Ruan, ED; Thacker, R; Yang, X | 1 |
| Houser, TA; Hunt, MC; Smith, JS; Vangnai, K | 1 |
| Cooper, KM; Cuskelly, G; Jankhaikhot, N | 1 |
| Gibis, M; Kruwinnus, M; Weiss, J | 1 |
| Artioli, GG; Carpentier, A; Dantas, WS; Dörr, FA; Fernandes, AL; Gualano, B; Murai, IH; Pereira, RT; Pinto, E; Poortmans, JR; Roschel, H; Santinho, MA; Seguro, AC; Solis, MY | 1 |
| Daniel, CR; Karam, JA; Matin, SF; Melkonian, SC; Tannir, NM; Wood, CG; Wu, X; Ye, Y | 1 |
| Baffet, G; Bellamri, M; Langouët, S; Le Hegarat, L; Turesky, RJ; Vernhet, L | 1 |
| Guo, J; Krishna, S; Murugan, P; Tejpaul, R; Turesky, RJ; Villalta, PW; Weight, CJ; Xiao, S; Yun, BH | 1 |
| Castaño, PR; Linseisen, J; Martínez Góngora, V; Matthes, KL; Rohrmann, S | 1 |
| Chen, J; He, Z; Li, Y; Qin, F; Quan, W; Wang, J; Wang, Z; Zeng, M | 1 |
13 review(s) available for 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
| Article | Year |
|---|---|
Chemical methods for assessing systemic exposure to dietary heterocyclic amines in man.
Topics: Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Food Handling; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Meat; Mutagens; Oxidoreductases; Quinoxalines | 1996 |
Enzymic and interindividual differences in the human metabolism of heterocyclic amines.
Topics: Animals; Biotransformation; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Food Handling; Gene Expression Regulation, Enzymologic; Humans; Hydroxylation; Imidazoles; Liver; Meat Products; Mutagens; Oxidation-Reduction; Oxidoreductases; Quinoxalines; Species Specificity | 1996 |
Extrapolation of heterocyclic amine carcinogenesis data from rodents and nonhuman primates to humans.
Topics: Amines; Animals; Biotransformation; Carcinogens; Diet; Food Handling; Heterocyclic Compounds; Humans; Imidazoles; Meat; Mice; Mutagens; Neoplasms; Primates; Quinoxalines; Rats; Risk Assessment; Species Specificity; Structure-Activity Relationship | 1996 |
Human exposure to carcinogenic heterocyclic amines and their mutational fingerprints in experimental animals.
Topics: Amines; Animals; Carcinogens, Environmental; DNA Adducts; Environmental Exposure; Food Contamination; Heterocyclic Compounds; Humans; Imidazoles; Mutagens; Mutation; Neoplasms; Quinoxalines | 1996 |
Heterocyclic amines: evaluation of their role in diet associated human cancer.
Topics: Animals; Biological Availability; Carcinogens; Diet; Humans; Imidazoles; Meat; Mutagens; Neoplasms; Quinoxalines | 1996 |
Exposure to and activation of dietary heterocyclic amines in humans.
Topics: Animals; Biological Availability; Biotransformation; Carcinogens; Colorectal Neoplasms; Cooking; Cytochrome P-450 CYP1A2; Diet; DNA Adducts; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Liver; Meat; Mutagenicity Tests; Mutagens; Proteins; Quinolines; Quinoxalines; Rats; Risk Assessment | 1995 |
Assessment of the DNA adduction and pharmacokinetics of PhIP and MeIOx in rodents at doses approximating human exposure using the technique of accelerator mass spectrometry (AMS) and 32P-postlabeling.
Topics: Animals; Carcinogens; DNA Adducts; Humans; Imidazoles; Mass Spectrometry; Mutagens; Neoplasms; Phosphorus Radioisotopes; Quinoxalines; Radioisotope Dilution Technique; Rodentia | 1995 |
Activation and effects of the food-derived heterocyclic amines in extrahepatic tissues.
Topics: Amines; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Cell Line; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; DNA Damage; Food; Heterocyclic Compounds; Hot Temperature; Humans; Hypoxanthine Phosphoribosyltransferase; Imidazoles; Lung; Meat; Mice; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens; Quinoxalines; Rats | 1995 |
Enzymatic studies of the activation of heterocyclic food mutagens in man.
Topics: Animals; Biotransformation; Callithrix; Cattle; Cooking; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Macaca fascicularis; Meat; Microsomes, Liver; Mutagens; Quinoxalines; Rabbits; Substrate Specificity | 1995 |
Systemic exposure to dietary heterocyclic amines in man.
Topics: Animals; Biotransformation; Cattle; Cooking; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Diet; Environmental Exposure; Enzyme Inhibitors; Hot Temperature; Humans; Imidazoles; Meat; Metabolic Clearance Rate; Mutagens; Quinoxalines; Theophylline | 1995 |
Biomarkers of exposure to heterocyclic amines: approaches to improve the exposure assessment.
Topics: Animals; Biomarkers; Carcinogens; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Monitoring; Hair; Heterocyclic Compounds; Humans; Imidazoles; Mice; Quinoxalines | 2002 |
An epidemiologic approach to studying heterocyclic amines.
Topics: Amines; Animals; Carcinogens; Cooking; Diet; Dietary Proteins; Epidemiologic Studies; Heterocyclic Compounds; Humans; Imidazoles; Meat Products; Neoplasms; Quinoxalines; Risk Factors; Surveys and Questionnaires | 2002 |
Dietary Heterocyclic Amine Intake and Colorectal Adenoma Risk: A Systematic Review and Meta-analysis.
Topics: Adenoma; Adult; Aged; Amines; Benzo(a)pyrene; Colorectal Neoplasms; Diet; Female; Heterocyclic Compounds; Humans; Imidazoles; Male; Meat; Middle Aged; Mutagens; Odds Ratio; Quinoxalines; Red Meat | 2019 |
3 trial(s) available for 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
| Article | Year |
|---|---|
CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans.
Topics: Adult; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Imidazoles; Male; Oxidoreductases; Phenacetin; Quinoxalines; Theophylline | 1994 |
A prospective study of meat and meat mutagens and prostate cancer risk.
Topics: Aged; Benzo(a)pyrene; Cooking; Diet; Humans; Imidazoles; Male; Meat; Middle Aged; Mutagens; Prospective Studies; Prostatic Neoplasms; Quinoxalines; Risk Factors; Surveys and Questionnaires | 2005 |
Can creatine supplementation form carcinogenic heterocyclic amines in humans?
Topics: Adult; Amines; Carcinogens; Creatine; Cross-Over Studies; Diet; Female; Furans; Humans; Imidazoles; Male; Quinoxalines; Single-Blind Method | 2015 |
130 other study(ies) available for 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
| Article | Year |
|---|---|
Inhibition of the metabolism of mutagens occurring in food by arachidonic acid.
Topics: Aflatoxin B1; Animals; Antimutagenic Agents; Arachidonic Acid; Biotransformation; DNA Repair; Food; Imidazoles; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium | 1992 |
Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl- 6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef.
Topics: Adult; Animals; Carcinogens; Cattle; Cooking; Gas Chromatography-Mass Spectrometry; Genetic Variation; Humans; Imidazoles; Individuality; Male; Meat; Mutagens; Quinoxalines | 1992 |
Metabolic activation and genotoxicity of heterocyclic arylamines.
Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; DNA; Heterocyclic Compounds; Imidazoles; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Polychlorinated Dibenzodioxins; Quinolines; Quinoxalines; Salmonella | 1992 |
Chemical analysis, prevention, and low-level dosimetry of heterocyclic amines from cooked food.
Topics: DNA; Food Analysis; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Meat; Mutagenicity Tests; Quinolines; Quinoxalines | 1992 |
Direct O-acetylation of N-hydroxy arylamines by acetylsalicylic acid to form carcinogen-DNA adducts.
Topics: Acetylation; Aminobiphenyl Compounds; Aspirin; Carcinogens; DNA; Fluorenes; Imidazoles; Quinolines; Quinoxalines | 1992 |
Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse.
Topics: Aminobiphenyl Compounds; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Imidazoles; Liver Neoplasms, Experimental; Male; Mice; Mutagens; Quinolines; Quinoxalines | 1992 |
Effects of the food mutagens MeIQx and PhIP on the expression of cytochrome P450IA proteins in various tissues of male and female rats.
Topics: Animals; Binding, Competitive; Blotting, Northern; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation; Imidazoles; Intestines; Kidney; Liver; Lung; Male; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA | 1990 |
Presence of carcinogenic heterocyclic amines in urine of healthy volunteers eating normal diet, but not of inpatients receiving parenteral alimentation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbolines; Diet; Female; Humans; Imidazoles; Male; Middle Aged; Parenteral Nutrition, Total; Quinoxalines | 1991 |
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
Topics: Acetylation; Amines; Animals; Biotransformation; Carcinogens; Colon; Cytochrome P-450 Enzyme System; Cytosol; Heterocyclic Compounds; Humans; Imidazoles; Liver; Microsomes, Liver; Mutagens; Oxidation-Reduction; Quinolines; Quinoxalines; Rats | 1991 |
The formation of heart DNA adducts in F344 rat following dietary administration of heterocyclic amines.
Topics: Administration, Oral; Aging; Amines; Animals; Carbolines; Diet; DNA; DNA Damage; Heart; Imidazoles; Kinetics; Liver; Male; Myocardium; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1991 |
DNA dosimetry following carcinogen exposure using accelerator mass spectrometry and 32P-postlabeling.
Topics: Animals; Binding Sites; Carcinogens; DNA; DNA Damage; Humans; Imidazoles; Mass Spectrometry; Mice; Phosphorus Radioisotopes; Quinoxalines | 1991 |
Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates.
Topics: Animals; Chromatography, High Pressure Liquid; DNA; DNA Damage; Dose-Response Relationship, Immunologic; Imidazoles; Liver Neoplasms, Experimental; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines | 1990 |
Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
Topics: 2-Acetylaminofluorene; Adolescent; Adult; Aged; Benzo(a)pyrene; Cell Line; Child; Cytochrome P-450 Enzyme System; Food Contamination; Gene Expression; Humans; Hydroxylation; Imidazoles; Microsomes, Liver; Middle Aged; Quinolines; Quinoxalines | 1990 |
The food-mutagens 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine (PhIP) and 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline (MeIQx) initiate enzyme-altered hepatic foci in the resistant hepatocyte model.
Topics: Animals; Diethylnitrosamine; Drug Resistance; gamma-Glutamyltransferase; Imidazoles; Liver; Male; Meat; Mutagens; Quinoxalines; Rats; Rats, Inbred Strains | 1989 |
Mutagenic and carcinogenic heterocyclic amines in Chinese cooked foods.
Topics: China; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cooking; Diet; Food Analysis; Heterocyclic Compounds; Imidazoles; Mutagenicity Tests; Mutagens; Mutation; Neoplasms; Quinolines; Quinoxalines | 1988 |
Heterocyclic aromatic amine content of selected beef flavors.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Creatine; Creatinine; Dose-Response Relationship, Drug; Flavoring Agents; Imidazoles; Linear Models; Meat Products; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella typhimurium | 1994 |
Heterocyclic amine content in fast-food meat products.
Topics: Amines; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Food Contamination; Heterocyclic Compounds; Imidazoles; Maryland; Meat Products; Mutagenicity Tests; Mutagens; Quinoxalines; Reference Standards | 1995 |
Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans.
Topics: Carcinogens; Cooking; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hot Temperature; Humans; Imidazoles; Male; Meat; Oxidoreductases; Polycyclic Compounds; Quinoxalines | 1994 |
Effect of microwave pretreatment on heterocyclic aromatic amine mutagens/carcinogens in fried beef patties.
Topics: Amines; Amino Acids; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Cooking; Creatine; Creatinine; Food Irradiation; Glucose; Heterocyclic Compounds; Imidazoles; Meat; Microwaves; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella | 1994 |
Effect of cooking time and temperature on the heterocyclic amine content of fried beef patties.
Topics: Animals; Cattle; Cooking; Hot Temperature; Imidazoles; Meat; Mutagens; Quinolines; Quinoxalines; Time Factors | 1994 |
Occurrence of mutagenic/carcinogenic heterocyclic amines in meat and fish products, including pan residues, prepared under domestic conditions.
Topics: Antioxidants; Carcinogens; Cooking; Fish Products; Imidazoles; Meat Products; Mutagens; Quinolines; Quinoxalines | 1994 |
Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.
Topics: Animals; Dogs; Glucuronates; Imidazoles; In Vitro Techniques; Male; Microsomes, Liver; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1994 |
Prevention of heterocyclic amine formation by tea and tea polyphenols.
Topics: Antineoplastic Agents; Biflavonoids; Carcinogens; Catechin; Gallic Acid; Imidazoles; Quinoxalines; Tea | 1994 |
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
Topics: Animals; Colon; Cytosol; DNA; Glutathione; Glutathione Transferase; Humans; Imidazoles; Liver; Quinolines; Quinoxalines; Rats | 1994 |
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a potent mutagen in the mouse small intestine.
Topics: Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Heterozygote; Hydroxylation; Imidazoles; Immunohistochemistry; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Microsomes; Microsomes, Liver; Mutagenesis; Mutagens; Oxidoreductases; Quinoxalines | 1994 |
Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human.
Topics: Animals; Biotransformation; Callithrix; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Imidazoles; Immunoblotting; Macaca fascicularis; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Species Specificity | 1994 |
Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats.
Topics: Acetyltransferases; Amino Acyl-tRNA Synthetases; Animals; Colon; Cytosol; DNA; Imidazoles; Kidney; Liver; Macaca fascicularis; Male; Myocardium; Phosphoric Monoester Hydrolases; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Species Specificity; Sulfotransferases | 1993 |
Excretion of food-derived heterocyclic amine carcinogens into breast milk of lactating rats and formation of DNA adducts in the newborn.
Topics: Animal Feed; Animals; Animals, Newborn; Carcinogens; DNA; Female; Imidazoles; Kidney; Lactation; Liver; Mammary Glands, Animal; Milk; Mutagenicity Tests; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Salmonella typhimurium | 1993 |
Heterocyclic aromatic amine formation in grilled bacon, beef and fish and in grill scrapings.
Topics: Animals; Carbolines; Carcinogens; Cattle; Cooking; Fishes; Hot Temperature; Imidazoles; Meat; Quinoxalines; Swine; Time Factors | 1993 |
Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline and 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine, carcinogens present in cooked beef. Cancer Res., 52: 6216-6223, 1992.
Topics: Animals; Carcinogens, Environmental; Cattle; Cooking; Humans; Imidazoles; Meat; Quinoxalines | 1993 |
Exposure to heterocyclic amines.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Animals; Carcinogens; Female; Food Contamination; Heterocyclic Compounds; Humans; Imidazoles; Male; Middle Aged; Mutagens; Quinoxalines | 1993 |
Immunoaffinity purification of dietary heterocyclic amine carcinogens.
Topics: Animals; Carcinogens; Cattle; Chromatography, Affinity; Diet; Food Contamination; Hot Temperature; Humans; Imidazoles; Meat; Quinoxalines; Rats | 1993 |
32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
Topics: Animals; Autoradiography; Chromatography, High Pressure Liquid; DNA; DNA Damage; Haplorhini; Imidazoles; Liver; Mutagens; Phosphorus Radioisotopes; Polynucleotides; Quinolines; Quinoxalines | 1993 |
Quantification of the carcinogens 2-amino-3,8-dimethyl- and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in food using a combined assay based on gas chromatography-negative ion mass spectrometry.
Topics: Animals; Carcinogens; Cattle; Chickens; Gas Chromatography-Mass Spectrometry; Imidazoles; Isotope Labeling; Meat; Meat Products; Mutagens; Quinoxalines; Reference Standards; Swine | 1993 |
Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Activation; Food; Hot Temperature; Imidazoles; Lung; Male; Mice; Microsomes; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinoxalines; Rats; Rats, Wistar | 1993 |
Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
Topics: Animals; Biotransformation; DNA Damage; Female; Humans; Imidazoles; Macaca fascicularis; Male; Microsomes, Liver; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Species Specificity; Tissue Distribution | 1993 |
Presence of N2-(deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (dG-C8-MeIQx) in human tissues.
Topics: Aged; Aged, 80 and over; Carcinogens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA Adducts; Female; Humans; Imidazoles; Male; Middle Aged; Quinoxalines | 1996 |
Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
Topics: Animals; Biotransformation; Carcinogens; Cooking; Food; Hot Temperature; Imidazoles; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines | 1995 |
Studies on the carcinogenic and myocardial effects of 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in nonhuman primates.
Topics: Administration, Oral; Animals; Carcinogens; Cooking; DNA Adducts; Fibrosis; Heart; Hot Temperature; Humans; Imidazoles; Inflammation; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Macaca fascicularis; Meat; Myocardium; Necrosis; Quinolines; Quinoxalines | 1995 |
Laparoscopy as a means of monitoring liver tumor induction in nonhuman primates.
Topics: Animals; Carcinogens; Equipment Design; Imidazoles; Laparoscopes; Laparoscopy; Liver Neoplasms, Experimental; Macaca mulatta; Palpation; Quinolines; Quinoxalines; Reproducibility of Results; Time Factors | 1995 |
Genetic alterations in HCA-induced tumors.
Topics: Animals; Carcinogens; Colonic Neoplasms; Diet; Female; Food; Genes, p53; Genes, ras; Humans; Imidazoles; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mutagenesis; Mutagens; Neoplasms, Experimental; Point Mutation; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Stomach Neoplasms | 1995 |
Effect of commercial marinades on the mutagenic activity, sensory quality and amount of heterocyclic amines in chicken grilled under different conditions.
Topics: Animals; Carcinogens; Chickens; Food Additives; Food Contamination; Food Handling; Food Preservation; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans; Imidazoles; Meat; Mutagenicity Tests; Mutagens; Quinoxalines; Taste | 1996 |
An overview of cancer prevention.
Topics: beta Carotene; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Environmental Exposure; Humans; Imidazoles; Mutagens; Neoplasms; Neoplasms, Unknown Primary; Precancerous Conditions; Primary Prevention; Quinoxalines; Risk Factors | 1996 |
Analysis of foods for heterocyclic aromatic amine carcinogens by solid-phase extraction and high-performance liquid chromatography.
Topics: Amines; Animals; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Heterocyclic Compounds; Imidazoles; Meat; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet | 1997 |
Effects of marinating on heterocyclic amine carcinogen formation in grilled chicken.
Topics: Amines; Animals; Chickens; Chromatography, High Pressure Liquid; Cooking; Food Analysis; Heterocyclic Compounds; Imidazoles; Meat; Mutagenicity Tests; Mutagens; Quinoxalines; Salmonella typhimurium | 1997 |
Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
Topics: Animals; Arylamine N-Acetyltransferase; Cattle; Cytochrome P-450 CYP1A2; Female; Hot Temperature; Humans; Imidazoles; Male; Meat; Phenotype; Quinoxalines | 1997 |
Quantification of mutagenic/carcinogenic heterocyclic amines, MeIQx, Trp-P-1, Trp-P-2 and PhIP, contributing highly to genotoxicity of river water.
Topics: Amines; Animals; Carbolines; Carcinogens; Cellulose; Chromatography, High Pressure Liquid; Fresh Water; Imidazoles; In Vitro Techniques; Japan; Mutagenicity Tests; Mutagens; Quinoxalines; Rats; Salmonella typhimurium; Water Pollutants, Chemical | 1997 |
Assessment of the human exposure to heterocyclic amines.
Topics: Aged; Carcinogens; Female; Food Handling; Hot Temperature; Humans; Imidazoles; Male; Middle Aged; Mutagens; Quinolines; Quinoxalines | 1997 |
In vivo genotoxicity of heterocyclic amines detected by a modified alkaline single cell gel electrophoresis assay in a multiple organ study in the mouse.
Topics: Amines; Animals; Brain; Carbolines; DNA Damage; Electrophoresis; Imidazoles; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Mutagens; Quinolines; Quinoxalines; Stomach | 1997 |
Effect of some cooked food mutagens on unscheduled DNA synthesis in cultured precision-cut rat, mouse and human liver slices.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Autoradiography; Carbolines; Cooking; Culture Techniques; DNA; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Liver; Male; Mice; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1998 |
Inhibitory effects of antioxidants on formation of heterocyclic amines.
Topics: Animals; Antimutagenic Agents; Antioxidants; Biotransformation; Imidazoles; Mutagens; Quinoxalines; Rats; Tea | 1998 |
Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
Topics: Animals; Biotransformation; Carcinogens; Cytochrome P-450 CYP1A2; Humans; Imidazoles; Male; Microsomes, Liver; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1998 |
Application of accelerated mass spectrometry (AMS) in DNA adduct quantification and identification.
Topics: DNA Adducts; Imidazoles; Mass Spectrometry; Quinoxalines; Sensitivity and Specificity | 1998 |
Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.
Topics: Animals; Biotransformation; Carbolines; Carcinogens, Environmental; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Food; Hot Temperature; Humans; Imidazoles; Lymphocytes; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Structure-Activity Relationship | 1999 |
Urinary excretion of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in White, African-American, and Asian-American men in Los Angeles County.
Topics: Adult; Asian; Black People; Humans; Imidazoles; Los Angeles; Male; Meat; Neoplasms; Quinoxalines; Surveys and Questionnaires; White People | 1999 |
Carcinogenic risk assessment of MeIQx and PhIP in a newborn mouse two-stage tumorigenesis assay.
Topics: Animals; Animals, Newborn; Biological Assay; Carcinogens; Imidazoles; Mice; Neoplasms, Experimental; Quinoxalines; Risk | 1999 |
Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocylic amines.
Topics: Catalysis; Cells, Cultured; Cytochrome P-450 CYP1A2; Gene Expression; Humans; Imidazoles; Mutagenicity Tests; Mutagens; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Plasmids; Quinoxalines; Salmonella | 1999 |
Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses.
Topics: Animals; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Humans; Imidazoles; Macromolecular Substances; Mice; Quinoxalines; Rats | 1999 |
Comparative biotransformation studies of MeIQx and PhIP in animal models and humans.
Topics: Animals; Carbon Radioisotopes; Carcinogens; Colon; DNA Adducts; Humans; Imidazoles; Quinoxalines; Rats; Species Specificity | 1999 |
Role of well-done, grilled red meat, heterocyclic amines (HCAs) in the etiology of human cancer.
Topics: Carcinogens; Colorectal Neoplasms; Humans; Imidazoles; Meat Products; Quinoxalines | 1999 |
Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
Topics: Animals; Caffeine; Carcinogens; Colonic Neoplasms; Drug Synergism; Imidazoles; Liver Neoplasms, Experimental; Male; Phosphodiesterase Inhibitors; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1999 |
Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells.
Topics: Amines; Animals; Arylamine N-Acetyltransferase; Carbolines; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Survival; CHO Cells; Cricetinae; Heterocyclic Compounds; Humans; Imidazoles; Liver Neoplasms; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella; Tumor Cells, Cultured | 1999 |
Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype.
Topics: Adult; Aged; Arylamine N-Acetyltransferase; Breast Neoplasms; Carcinogens; Cooking; Diet; Female; Genotype; Humans; Imidazoles; Meat; Middle Aged; Mutagens; Quinoxalines; Risk Factors | 2000 |
Dietary heterocyclic amines and the risk of lung cancer among Missouri women.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Female; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Lung Neoplasms; Middle Aged; Missouri; Multivariate Analysis; Quinoxalines; Risk Factors; Smoking | 2000 |
Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay.
Topics: Animals; Antimutagenic Agents; Catechin; Chromatography, High Pressure Liquid; Cooking; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidoreductases; Quinolines; Quinoxalines; Rats; Salmonella typhimurium; Tea | 2001 |
Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man.
Topics: Adult; Biomarkers; Biotransformation; Brassica; Caffeine; Carcinogens; Cytochrome P-450 CYP1A2; Deoxyguanosine; DNA; Humans; Imidazoles; Lymphocytes; Male; Meat; Middle Aged; Quinoxalines | 2001 |
Natural variations of precursors in pig meat affect the yield of heterocyclic amines--effects of RN genotype, feeding regime, and sex.
Topics: Animals; Carcinogens; Eating; Female; Genotype; Harmine; Hot Temperature; Imidazoles; Male; Meat; Mutagens; Quinoxalines; Sex Characteristics; Swine | 2002 |
Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk.
Topics: Adult; Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases; Arylsulfotransferase; Carcinogens; Case-Control Studies; Colorectal Neoplasms; Cooking; Cytochrome P-450 CYP2A6; Diet; Eating; Environmental Exposure; Female; Genotype; Glutathione Transferase; Humans; Imidazoles; Male; Meat Products; Middle Aged; Mixed Function Oxygenases; Polymerase Chain Reaction; Quinoxalines; Sulfotransferases | 2002 |
Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
Topics: Animals; Biotransformation; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Hepatocytes; Humans; Imidazoles; Liver; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Species Specificity; Theophylline | 2002 |
Estimation of dietary HCA intakes in a large-scale population-based prospective study in Japan.
Topics: Adult; Amines; Carcinogens; Cooking; Diet Surveys; Female; Heterocyclic Compounds; Humans; Imidazoles; Japan; Male; Meat; Middle Aged; Population; Prospective Studies; Quinolines; Quinoxalines | 2002 |
Effects of cigarette smoke and a heterocyclic amine, MeIQx on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver.
Topics: Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Cocarcinogenesis; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Enzyme Induction; Glucuronosyltransferase; Imidazoles; Liver; Liver Neoplasms, Experimental; Male; Membrane Proteins; Microsomes, Liver; Quinoxalines; Rats; Rats, Inbred F344; Smoke; Specific Pathogen-Free Organisms; Steroid Hydroxylases; Substrate Specificity | 2003 |
A model system study of the inhibition of heterocyclic aromatic amine formation by organosulfur compounds.
Topics: Allyl Compounds; Amines; Creatinine; Disulfides; Glucose; Heterocyclic Compounds; Hot Temperature; Imidazoles; Phenylalanine; Quinoxalines; Sulfites; Sulfur Compounds; Volatilization | 2002 |
Effect of high water-holding capacity on the formation of heterocyclic amines in fried beefburgers.
Topics: Animals; Carcinogens; Cattle; Heterocyclic Compounds; Hot Temperature; Imidazoles; Meat; Quinoxalines; Water | 2003 |
Mutagenic activity and heterocyclic amine carcinogens in commercial pet foods.
Topics: Amines; Animals; Animals, Domestic; Carcinogens; Food Analysis; Heterocyclic Compounds; Imidazoles; Mutagenicity Tests; Mutagens; Quinoxalines; Salmonella typhimurium | 2003 |
Phytoalexin resveratrol attenuates the mutagenicity of the heterocyclic amines 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Topics: Animals; Antimutagenic Agents; Cell Line; Cricetinae; Imidazoles; Mutagens; Phytoalexins; Plant Extracts; Quinoxalines; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes | 2004 |
Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cycloox
Topics: Adenocarcinoma; Animals; Anticoagulants; Base Sequence; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Imidazoles; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Restriction Mapping; Trans-Activators | 2005 |
Heterocyclic amines in some Swedish cooked foods industrially prepared or from fast food outlets and restaurants.
Topics: Amines; Animals; Carcinogens; Cooking; Food Analysis; Food Handling; Heterocyclic Compounds; Imidazoles; Meat; Mutagens; Quinolines; Quinoxalines; Restaurants; Sweden | 2004 |
Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Diet; Drug Therapy, Combination; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Quinolines; Quinoxalines | 2005 |
A comparison of genotoxicity between three common heterocyclic amines and acrylamide.
Topics: Acrylamide; Animals; Dose-Response Relationship, Drug; Erythrocytes; Heterocyclic Compounds; Imidazoles; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Mutagens; Quinolines; Quinoxalines; Structure-Activity Relationship | 2005 |
Formation of a mutagenic heterocyclic aromatic amine from creatinine in urine of meat eaters and vegetarians.
Topics: Creatinine; Diet, Vegetarian; Humans; Imidazoles; Male; Meat; Mutagens; Quinoxalines; Spectrometry, Mass, Electrospray Ionization | 2005 |
Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.
Topics: Acetonitriles; Amines; Buffers; Carbolines; Chromatography, Liquid; Formates; Harmine; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Quinolines; Quinoxalines; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Meat, meat cooking methods and preservation, and risk for colorectal adenoma.
Topics: Adenoma; Aged; Benzo(a)pyrene; Carcinogens; Colorectal Neoplasms; Cooking; Diet; Female; Food Preservation; Humans; Imidazoles; Male; Meat; Middle Aged; Mutagens; Quinoxalines | 2005 |
PhIP carcinogenicity in breast cancer: computational and experimental evidence for competitive interactions with human estrogen receptor.
Topics: Binding, Competitive; Carcinogens; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Furans; Hot Temperature; Humans; Imidazoles; Meat; Quinoxalines | 2005 |
Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.
Topics: Acetylation; Arylamine N-Acetyltransferase; Carcinogens; Genotype; Humans; Imidazoles; Phenotype; Polymorphism, Single Nucleotide; Quinoxalines | 2006 |
Heterocyclic amines in griddled beef steak analysed using a single extract clean-up procedure.
Topics: Amines; Animals; Cattle; Cooking; Heterocyclic Compounds; Imidazoles; Meat; Mutagens; Quinoxalines | 2007 |
Inhibitory activities of dietary phenolic compounds on heterocyclic amine formation in both chemical model system and beef patties.
Topics: Animals; Antioxidants; Catechin; Cattle; Chromatography, High Pressure Liquid; Cinnamates; Creatinine; Depsides; Diet; Flavanones; Flavonoids; Glucose; Imidazoles; Meat; Models, Chemical; Phenols; Phenylalanine; Polyphenols; Quinoxalines; Rosmarinic Acid | 2007 |
Tobacco smoking and urinary levels of 2-amino-9H-pyrido[2,3-b]indole in men of Shanghai, China.
Topics: Animals; Carbolines; Carcinogens; Case-Control Studies; Chickens; China; Cohort Studies; Creatinine; Follow-Up Studies; Humans; Imidazoles; Male; Meat; Middle Aged; Population Surveillance; Prospective Studies; Quinoxalines; Smoking; Swine | 2007 |
Inhibitory effect of fruit extracts on the formation of heterocyclic amines.
Topics: Ananas; Animals; Cattle; Fruit; Heterocyclic Compounds; Hot Temperature; Imidazoles; Malus; Meat; Plant Extracts; Proanthocyanidins; Quinoxalines; Sambucus; Seeds; Vitis | 2007 |
Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial.
Topics: Anticarcinogenic Agents; Antimutagenic Agents; Carbolines; Carcinogens; Food Handling; Heterocyclic Compounds; Hot Temperature; Imidazoles; Lactobacillus; Meat; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines | 2008 |
Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Brain; Cell Line; Dantrolene; Dogs; Imidazoles; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Prazosin; Quinoxalines; Swine; Testis; Triamterene; Xenobiotics | 2008 |
Carcinogenic risk of heterocyclic amines in combination - assessment with a liver initiation model.
Topics: Amines; Animals; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; DNA, Complementary; Glutathione Transferase; Hepatocytes; Heterocyclic Compounds; Imidazoles; Liver; Liver Neoplasms; Male; Oligonucleotide Array Sequence Analysis; Quinoxalines; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Risk | 2008 |
Quantification of heterocyclic aromatic amines in fried meat by HPTLC/UV-FLD and HPLC/UV-FLD: a comparison of two methods.
Topics: Amines; Animals; Carbolines; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Harmine; Heterocyclic Compounds; Hot Temperature; Imidazoles; Meat; Mutagens; Quinoxalines | 2008 |
Effect of beer/red wine marinades on the formation of heterocyclic aromatic amines in pan-fried beef.
Topics: Animals; Beer; Carcinogens; Cattle; Food Handling; Heterocyclic Compounds; Hot Temperature; Humans; Imidazoles; Meat; Quinolines; Quinoxalines; Sensation; Wine | 2008 |
Intakes of red meat, processed meat, and meat mutagens increase lung cancer risk.
Topics: Aged; Animals; Case-Control Studies; Cattle; Chickens; Female; Humans; Imidazoles; Italy; Lung Neoplasms; Male; Meat; Meat Products; Middle Aged; Mutagens; Quinoxalines | 2009 |
Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitro.
Topics: Amines; Aminopyridines; Analysis of Variance; Cells, Cultured; Chromatography, High Pressure Liquid; Colony Count, Microbial; Comet Assay; DNA Damage; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Inactivation, Metabolic; Lacticaseibacillus casei; Mutagens; Probiotics; Quinolines; Quinoxalines; Spectrophotometry, Ultraviolet; Time Factors | 2009 |
Hollow fibre-supported liquid membrane extraction and LC-MS/MS detection for the analysis of heterocyclic amines in urine samples.
Topics: Analytic Sample Preparation Methods; Carbolines; Carcinogens; Chromatography, High Pressure Liquid; Harmine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Imidazoles; Limit of Detection; Microchemistry; Mutagens; Pyridines; Quinoxalines; Reproducibility of Results; Tandem Mass Spectrometry | 2009 |
A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
Topics: Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Humans; Imidazoles; Meat; Metabolome; Quinoxalines; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization | 2010 |
A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association.
Topics: Cohort Studies; Colorectal Neoplasms; Cooking; Diet; Female; Humans; Imidazoles; Male; Meat; Middle Aged; Prospective Studies; Quinoxalines; Surveys and Questionnaires; United States | 2010 |
Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme System; DNA Damage; Dose-Response Relationship, Drug; Humans; Imidazoles; Oxidative Stress; Polymerase Chain Reaction; Quinoxalines | 2010 |
Meat mutagens and breast cancer in postmenopausal women--a cohort analysis.
Topics: Adult; Breast Neoplasms; Cohort Studies; Female; Humans; Imidazoles; Meat; Middle Aged; Mutagens; Nurses; Postmenopause; Quinoxalines; Risk Factors; Surveys and Questionnaires | 2010 |
Inhibition of heterocyclic amine formation in beef patties by ethanolic extracts of rosemary.
Topics: Animals; Antioxidants; Cattle; Cooking; Ethanol; Food Analysis; Food Handling; Gas Chromatography-Mass Spectrometry; Heterocyclic Compounds, 2-Ring; Imidazoles; Meat Products; Plant Extracts; Quinoxalines; Rosmarinus; Solid Phase Microextraction; Time Factors; Water | 2010 |
Effects of (+)-catechin and (-)-epicatechin on heterocyclic amines-induced oxidative DNA damage.
Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Imidazoles; Oxidation-Reduction; Quinoxalines | 2011 |
Preferential induction of the AhR gene battery in HepaRG cells after a single or repeated exposure to heterocyclic aromatic amines.
Topics: Amines; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Quinoxalines; Receptors, Aryl Hydrocarbon | 2010 |
Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia.
Topics: Aged; Amines; Aryl Hydrocarbon Receptor Nuclear Translocator; Arylamine N-Acetyltransferase; Biotransformation; Carcinogens; Case-Control Studies; Colorectal Neoplasms; Female; Genetic Variation; Genotype; Humans; Imidazoles; Male; Middle Aged; Polycyclic Aromatic Hydrocarbons; Polymorphism, Single Nucleotide; Quinoxalines; Risk Factors | 2011 |
Selected heterocyclic amines.
Topics: Amines; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Environmental Exposure; Female; Government Regulation; Guidelines as Topic; Heterocyclic Compounds; Humans; Imidazoles; Macaca fascicularis; Male; Mice; Models, Biological; Quinolines; Quinoxalines; Rats; United States | 2004 |
Ultraperformance liquid chromatography-tandem mass spectrometry method for biomonitoring cooked meat carcinogens and their metabolites in human urine.
Topics: Carcinogens; Chromatography, Liquid; Cooking; Humans; Imidazoles; Meat; Molecular Structure; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Urinalysis | 2011 |
Anti-genotoxic activity of Vitis coignetiae Pulliat towards heterocyclic amines and isolation and identification of caftaric acid as an antimutagenic component from the juice.
Topics: Animals; Antimutagenic Agents; DNA Adducts; Fruit; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mutagens; Phenols; Quinoxalines; Vitis | 2011 |
Inhibitory activity of Asian spices on heterocyclic amines formation in cooked beef patties.
Topics: Amines; Animals; Antioxidants; Cattle; Cooking; Curcuma; Hot Temperature; Imidazoles; Meat Products; Oils, Volatile; Phenols; Plant Extracts; Quinoxalines; Rosmarinus; Spices | 2011 |
[Simultaneous determination of 9 heterocyclic aromatic amine in poultry products by solid-phase extraction-high performance liquid chromatography].
Topics: Amines; Animals; Carcinogens; Chromatography, High Pressure Liquid; Food Analysis; Food Contamination; Heterocyclic Compounds; Imidazoles; Poultry Products; Quinoxalines; Solid Phase Extraction | 2011 |
Occurrence of heterocyclic amines in cooked meat products.
Topics: Amines; Animals; Cattle; Chickens; Chromatography, High Pressure Liquid; Consumer Product Safety; Cooking; Fishes; Heterocyclic Compounds; Hot Temperature; Imidazoles; Meat Products; Mutagens; Quinoxalines; Risk Factors; Swine | 2012 |
Protective effects of xanthohumol against the genotoxicity of heterocyclic aromatic amines MeIQx and PhIP in bacteria and in human hepatoma (HepG2) cells.
Topics: Cell Line, Tumor; Comet Assay; Flavonoids; Genomic Instability; Humans; Imidazoles; Mutagens; Propiophenones; Quinoxalines; Real-Time Polymerase Chain Reaction; Salmonella typhimurium | 2012 |
Plant extracts, spices, and essential oils inactivate Escherichia coli O157:H7 and reduce formation of potentially carcinogenic heterocyclic amines in cooked beef patties.
Topics: Animals; Anti-Bacterial Agents; Anticarcinogenic Agents; Carcinogens; Cattle; Clove Oil; Escherichia coli O157; Fruit; Hot Temperature; Imidazoles; Malus; Meat; Oils, Volatile; Olea; Onions; Plant Extracts; Quinoxalines; Spices | 2012 |
Formation of heterocyclic amines during cooking of duck meat.
Topics: Amines; Animals; Carbolines; China; Chromatography, High Pressure Liquid; Cooking; Ducks; Food Contamination; Harmine; Heterocyclic Compounds; Hot Temperature; Imidazoles; Maillard Reaction; Meat; Microwaves; Mutagens; Quinolines; Quinoxalines; Solid Phase Extraction; Time Factors | 2012 |
[Determination of 14 heterocyclic aromatic amines in wine by liquid chromatography-ion trap-time of flight tandem mass spectrometry].
Topics: Amines; Chromatography, Liquid; Food Contamination; Heterocyclic Compounds; Imidazoles; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Wine | 2012 |
Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Female; Food; Genomic Instability; Humans; Imidazoles; Long Interspersed Nucleotide Elements; Mice; Quinoxalines; Receptors, Aryl Hydrocarbon | 2013 |
Meat-related compounds and colorectal cancer risk by anatomical subsite.
Topics: Aged; Animals; Benzo(a)pyrene; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Cooking; Feeding Behavior; Female; Humans; Imidazoles; Logistic Models; Male; Meat; Meat Products; Middle Aged; Nitrates; Nitrites; Pennsylvania; Poultry; Quinoxalines; Rectal Neoplasms; Risk Factors; Surveys and Questionnaires | 2013 |
Formation of heterocyclic amines in salami and ham pizza toppings during baking of frozen pizza.
Topics: Amines; Animals; Carbolines; Chromatography, High Pressure Liquid; Color; Consumer Behavior; Cooking; Freezing; Harmine; Hot Temperature; Humans; Imidazoles; Maillard Reaction; Meat Products; Quinoxalines; Swine; Taste | 2013 |
Helicobacter pylori infection and antioxidants can modulate the genotoxic effects of heterocyclic amines in gastric mucosa cells.
Topics: Adult; Ascorbic Acid; Breath Tests; Carbon Isotopes; Comet Assay; DNA Damage; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Imidazoles; Male; Melatonin; Middle Aged; Poland; Quinoxalines; Statistics, Nonparametric | 2013 |
Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells.
Topics: Biotransformation; Carcinogens; Cell Cycle; Cell Survival; DNA Breaks; DNA Damage; Food Contamination; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Hot Temperature; Humans; Imidazoles; Mutagens; Quinolines; Quinoxalines | 2013 |
Formation and mitigation of heterocyclic aromatic amines in fried pork.
Topics: Animals; Antioxidants; Carcinogens; China; Cooking; Fast Foods; Food Contamination; Food Preservatives; Heterocyclic Compounds; Imidazoles; Meat; Meat Products; Mutagens; Plant Extracts; Plant Leaves; Polycyclic Aromatic Hydrocarbons; Quinoxalines; Sasa; Sus scrofa | 2013 |
Chemical state of heterocyclic aromatic amines in grilled beef: evaluation by in vitro digestion model and comparison of alkaline hydrolysis and organic solvent for extraction.
Topics: Amines; Animals; Carbolines; Cattle; Cooking; Digestion; Humans; Hydrolysis; Imidazoles; Male; Meat; Mutagens; Quinolines; Quinoxalines; Solvents | 2013 |
Dietary vitamin E effects on the formation of heterocyclic amines in grilled lean beef.
Topics: Amines; Animals; Antioxidants; Cattle; Chromatography, High Pressure Liquid; Cooking; Diet; Harmine; Imidazoles; Meat; Muscle, Skeletal; Mutagens; Quinoxalines; Salmonella; Vitamin E | 2014 |
Effect of enhancement on the formation of heterocyclic amines in cooked pork loins: preliminary studies.
Topics: Amines; Animals; Cooking; Creatine; Heterocyclic Compounds; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Meat; Phosphates; Quinoxalines; Salts; Swine; Water | 2014 |
Optimised extraction of heterocyclic aromatic amines from blood using hollow fibre membrane liquid-phase microextraction and triple quadrupole mass spectrometry.
Topics: Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Cooking; Humans; Hydrogen-Ion Concentration; Imidazoles; Liquid Phase Microextraction; Meat; Mutagens; Polypropylenes; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Impact of different pan-frying conditions on the formation of heterocyclic aromatic amines and sensory quality in fried bacon.
Topics: Animals; Cooking; Food Handling; Imidazoles; Meat Products; Quinoxalines; Temperature | 2015 |
Impact of Precursors Creatine, Creatinine, and Glucose on the Formation of Heterocyclic Aromatic Amines in Grilled Patties of Various Animal Species.
Topics: Acids, Heterocyclic; Amines; Amino Acids; Animals; Cattle; Chromatography, High Pressure Liquid; Cooking; Creatine; Creatinine; Glucose; Horses; Hot Temperature; Humans; Imidazoles; Meat; Mutagens; Poultry; Pyridines; Quinoxalines; Sheep; Swine | 2015 |
Gene-environment interaction of genome-wide association study-identified susceptibility loci and meat-cooking mutagens in the etiology of renal cell carcinoma.
Topics: Carcinoma, Renal Cell; Case-Control Studies; Disease Susceptibility; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Imidazoles; Kidney Neoplasms; Male; Meat; Middle Aged; Mutagens; Quinoxalines; Risk Factors; United States | 2016 |
Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts.
Topics: Activation, Metabolic; Carbolines; Cell Culture Techniques; Cells, Cultured; Chromatography, Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; Flow Cytometry; Humans; Imidazoles; Quinoxalines; Real-Time Polymerase Chain Reaction; Spectrometry, Mass, Electrospray Ionization; T-Lymphocytes | 2016 |
Biomonitoring DNA Adducts of Cooked Meat Carcinogens in Human Prostate by Nano Liquid Chromatography-High Resolution Tandem Mass Spectrometry: Identification of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine DNA Adduct.
Topics: Aged; Animals; Carcinogens; Cattle; Chromatography, Liquid; Cooking; DNA Adducts; Humans; Imidazoles; Limit of Detection; Male; Meat; Middle Aged; Nicotiana; Prostate; Quinoxalines; Smoke; Tandem Mass Spectrometry | 2016 |
Effects of ten vegetable oils on heterocyclic amine profiles in roasted beef patties using UPLC-MS/MS combined with principal component analysis.
Topics: Amines; Animals; Cattle; Chromatography, High Pressure Liquid; Cooking; Heterocyclic Compounds; Imidazoles; Limit of Detection; Meat; Plant Oils; Principal Component Analysis; Quinoxalines; Tandem Mass Spectrometry | 2021 |