2-amino-3,4-dimethylimidazo(4,5-f)quinoline has been researched along with 2-amino-3-methylimidazo(4,5-f)quinoline in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (48.53) | 18.7374 |
| 1990's | 30 (44.12) | 18.2507 |
| 2000's | 4 (5.88) | 29.6817 |
| 2010's | 1 (1.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abu-Shakra, A | 1 |
| Cheng, JT; Lin, JK; Lin-Shiau, SY | 1 |
| Brams, A; de Meester, C | 1 |
| Alexander, J; Holme, JA; Wallin, H | 1 |
| Grover, PL; O'Hare, MJ; Pfau, W; Phillips, DH | 1 |
| Crutzen-Fayt, MC; Duverger-van Bogaert, M; Stecca, C | 1 |
| Esumi, H; Kudo, M; Ogura, T; Sugimura, T | 1 |
| Fukushima, S; Hakoi, K; Hasegawa, R; Ito, N; Iwasaki, S; Nagao, M; Shirai, T; Sugimura, T; Takaba, K; Wakabayashi, K | 1 |
| Knudsen, I; Kristiansen, E; Meyer, O; Olsen, P; Thorup, I | 1 |
| Shin, S; Tachikawa, T; Wada, O; Yanagisawa, H | 1 |
| Burgess, WM; Huggett, A; McManus, ME; Quattrochi, LC; Tukey, RH; Veronese, ME | 1 |
| Fasshauer, I; Hall, M; Hewer, A; Phillips, DH; Shé, MN; Wild, D | 1 |
| Alexander, J; Becher, G; Holme, JA; Wallin, H | 1 |
| Clemmensen, S; Kristiansen, E; Olsen, P | 1 |
| Ayrton, AD; Bass, SL; Flatt, PR; Ioannides, C; Trinick, J; Walker, R | 1 |
| Jones, RC; Weisburger, JH | 1 |
| Felton, JS; Fuscoe, JC; Healy, SK; Shen, NH; Wu, R | 1 |
| Abu-Zeid, M; Kato, R; Yamauchi, K; Yamazoe, Y | 1 |
| Alexander, J; Dybing, E; Holme, JA | 1 |
| Alexander, J; Wallin, H | 1 |
| Alexander, J; Bjørnstad, C; Brunborg, G; Holme, JA; Trygg, B | 1 |
| Alldrick, AJ; Rowland, IR; Wise, A | 1 |
| Abu-Shakra, A; Ioannides, C; Walker, R | 1 |
| Liu, ZC; Nagao, M; Sugimura, T; Wakabayashi, K; Zhang, XM | 1 |
| Alldrick, AJ; Flynn, J; Lake, BG; Rowland, IR | 1 |
| Alexander, J; Brunborg, G; Christensen, T; Dybing, E; Holme, JA; Hongslo, JK; Søderlund, E | 1 |
| Alexander, J; Becher, G; Størmer, FC | 1 |
| Manabe, S; Wada, O; Yanagisawa, H | 1 |
| Beamand, JA; Howes, AJ; Rowland, IR | 1 |
| Nishimura, S | 1 |
| Hasegawa, H; Kato, T; Ohgaki, H; Sato, S; Suenaga, M; Sugimura, T; Takayama, S; Ubukata, M | 1 |
| Edmonds, CG; Kasai, H; McCloskey, JA; Nishimura, S; Sethi, SK; Yamaizumi, Z | 1 |
| O'Connell, JF; Rapoport, H; Thompson, CM; Waterhouse, AL | 1 |
| Fultz, E; Knize, M; Taylor, RT | 1 |
| Hasegawa, H; Kato, T; Ohgaki, H; Sato, S; Suenaga, M; Sugimura, T; Takayama, S | 2 |
| Caderni, G; Dolara, P; Salvadori, M; Santoni, G | 1 |
| Alldrick, AJ; Rowland, IR | 1 |
| Edmonds, CG; Kasai, H; McCloskey, JA; Nishimura, S; Yamaizumi, Z | 1 |
| Aune, KT; Aune, T | 1 |
| Bergman, K | 1 |
| Byard, JL; Loury, DJ | 1 |
| Jägerstad, M; Sjödin, P | 1 |
| Bjeldanes, LF; Felton, JS; Hatch, FT; Healy, SK; Kimble, BJ; Knize, MG; Stuermer, DH; Wood, C; Wuebbles, BJ | 1 |
| Hayashi, K; Kasai, H; Miyazawa, T; Nishimura, S; Watanabe, T; Yokoyama, S | 1 |
| Diachenko, GW; Hargraves, WA; Jackson, LS; Stroup, WH | 1 |
| Itahashi, K; Kamataki, T; Kato, T; Kitada, M; Nakasa, H; Ohmori, S; Rikihisa, T; Shimada, T | 1 |
| Gustafsson, JA; Nord, CE; Orrhage, K; Rafter, J; Sillerström, E | 1 |
| Edenharder, R; Kries, M; Leopold, C | 1 |
| Deguchi, T; Hashimoto, H; Itoh, S; Kamataki, T; Sawada, M; Yanagawa, Y | 1 |
| Hao, NJ; Lee, H; Lin, MY | 1 |
| Sasaki, YF; Shirasu, Y | 1 |
| Gross, GA; Skipper, PL; Stillwell, WG; Tannenbaum, SR; Turesky, RJ | 1 |
| Davis, CD; Ghoshal, A; Schut, HA; Snyderwine, EG | 1 |
| Burgard, S; Edenharder, R; John, K; Kurz, P; Seeger, K | 1 |
| Grover, PL; Hughes, NC; Lecoq, S; Pfau, W; Phillips, DH; Platt, KL; Seidel, A | 1 |
| Anari, MR; Henry, T; Josephy, PD; O'Brien, PJ | 1 |
| Darroudi, F; Knasmüller, S; Nagao, M; Parzefall, W; Sanyal, R | 1 |
| Akasaka, M; Matsusaka, N; Nishidate, E; Ohta, T; Saga, A; Sasaki, YF; Tsuda, S; Watanabe-Akanuma, M | 1 |
| Grover, PL; Gusterson, BA; Phillips, DH; Stone, EM; Williams, JA | 1 |
| Hosono, A; Sreekumar, O | 1 |
| Darroudi, F; Knasmüller, S; Kundi, M; Land, SJ; Parzefall, W; Sanyal, R; Schwab, CE; Wang, CY | 1 |
| Hori, Y; Kodama, K; Nakamura, K; Ogoshi, K; Ohta, T; Shibuya, N; Yamamoto, M | 1 |
| Antoine, JM; Cassand, P; Cayuela, C; Tavan, E | 1 |
| Guengerich, FP; Josephy, PD; Kim, D; Zhou, H | 1 |
| Bianchi, F; Careri, M; Corradini, C; Elviri, L; Mangia, A; Zagnoni, I | 1 |
| Agim, ZS; Cannon, JR; Cruz-Hernandez, A; McCabe, GP; Montenegro, PC; Rochet, JC | 1 |
1 review(s) available for 2-amino-3,4-dimethylimidazo(4,5-f)quinoline and 2-amino-3-methylimidazo(4,5-f)quinoline
| Article | Year |
|---|---|
Carcinogenesis of foods.
Topics: Animals; Carcinogens; Cooking; Dietary Fiber; Ethanol; Female; Food Contamination; Gastrointestinal Neoplasms; Lung Neoplasms; Mutagens; Quinolines; Urethane | 1990 |
67 other study(ies) available for 2-amino-3,4-dimethylimidazo(4,5-f)quinoline and 2-amino-3-methylimidazo(4,5-f)quinoline
| Article | Year |
|---|---|
The modulatory effects of tryptamine and tyramine on the S9-mediated mutagenesis of IQ and MeIQ in Salmonella strain TA98.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Microsomes, Liver; Mutagenicity Tests; Oxazines; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Salmonella typhimurium; Species Specificity; Tryptamines; Tyramine | 1992 |
Enhancement of the mutagenicity of IQ and MeIQ by nitrite in the Salmonella system.
Topics: Amines; Carbolines; Chromatography, Thin Layer; Drug Interactions; Imidazoles; Mutagenicity Tests; Mutagens; Nitrites; Nitrosation; Quinolines | 1992 |
Mutagenic potency of heterocyclic amines towards Salmonella typhimurium; possible causes of variability in the results observed.
Topics: Dose-Response Relationship, Drug; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Reproducibility of Results; Salmonella typhimurium | 1992 |
Covalent binding of food carcinogens MeIQx, MeIQ and IQ to DNA and protein in microsomal incubations and isolated rat hepatocytes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; DNA; Male; Microsomes, Liver; Mutagens; Protein Binding; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains | 1992 |
Metabolic activation of the food mutagens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) to DNA binding species in human mammary epithelial cells.
Topics: Biotransformation; Breast; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA; Female; Humans; Mutagens; Quinolines | 1992 |
Mutagenicity of some heterocyclic amines in Salmonella typhimurium with metabolic activation by human red blood cell cytosol.
Topics: Biotransformation; Carbolines; Carcinogenicity Tests; Cytosol; Dose-Response Relationship, Drug; Erythrocytes; Humans; Kinetics; Mutagenicity Tests; Mutagens; Quinolines; Salmonella typhimurium | 1991 |
Mutational activation of c-Ha-ras gene in squamous cell carcinomas of rat Zymbal gland induced by carcinogenic heterocyclic amines.
Topics: Animals; Carcinoma, Squamous Cell; Codon; Ear Neoplasms; Ear, External; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mutagens; Mutation; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Sebaceous Gland Neoplasms | 1991 |
Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses.
Topics: Animals; Body Weight; Carbolines; Carcinogens; Drug Synergism; Enzyme Induction; Glutathione Transferase; Imidazoles; Immunohistochemistry; Liver; Liver Neoplasms; Male; Organ Size; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1991 |
Monoclonal antibody to 2-amino-3-methylimidazo(4,5-f)quinoline, a dietary carcinogen.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens; Ascitic Fluid; Carbolines; Carcinogens; Chromatography, Affinity; Diet; Hybridomas; Immunoglobulin G; Mice; Mice, Inbred BALB C; Molecular Weight; Quinolines; Radioimmunoassay | 1990 |
Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
Topics: 2-Acetylaminofluorene; Adolescent; Adult; Aged; Benzo(a)pyrene; Cell Line; Child; Cytochrome P-450 Enzyme System; Food Contamination; Gene Expression; Humans; Hydroxylation; Imidazoles; Microsomes, Liver; Middle Aged; Quinolines; Quinoxalines | 1990 |
Tissue distribution of DNA adducts in CDF1 mice fed 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ).
Topics: Animals; Autoradiography; Carcinogens; Chromatography, Thin Layer; DNA; Female; Male; Mice; Mice, Inbred Strains; Phosphorus Radioisotopes; Quinolines; Tissue Distribution | 1990 |
Characterisation of metabolites of the food mutagens 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline formed after incubation with isolated rat liver cells.
Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; Glucuronates; Glucuronidase; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Mutagens; Polychlorinated Biphenyls; Quinolines; Rats; Rats, Inbred Strains | 1989 |
Carcinogenic potential of cooked food mutagens (IQ and MeIQ) in Wistar rats after short-term exposure.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Cell Division; Food Analysis; Liver; Male; Mutagens; Organ Size; Phenobarbital; Quinolines; Rats; Rats, Inbred Strains | 1989 |
Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens.
Topics: Animals; Biotransformation; Carbolines; Carcinogens; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Insulin; Isoenzymes; Male; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Mutagenicity Tests; Mutagens; Niacinamide; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains | 1988 |
Inhibition of aminoimidazoquinoxaline-type and aminoimidazol-4-one-type mutagen formation in liquid reflux models by L-tryptophan and other selected indoles.
Topics: Indoles; Mutagens; Quinolines; Quinoxalines; Structure-Activity Relationship; Tryptophan | 1988 |
Base-change analysis of revertants of the hisD3052 allele in Salmonella typhimurium.
Topics: Aflatoxin B1; Aflatoxins; Base Composition; Base Sequence; Benzo(a)pyrene; Carcinogens; Cloning, Molecular; DNA, Bacterial; Food; Histidine; Imidazoles; Molecular Sequence Data; Mutagens; Operon; Quinolines; Salmonella typhimurium | 1988 |
Metabolic activation of pyrolysate arylamines by human liver microsomes; possible involvement of a P-488-H type cytochrome P-450.
Topics: Adolescent; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Female; Humans; Imidazoles; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Mutagens; Quinolines | 1988 |
Mutagenic activation of 2-amino-3-methylimidazo[4,5-f]-quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]-quinoline (MeIQ) by subcellular fractions and cells isolated from small intestine, kidney and liver of the rat.
Topics: Animals; Biotransformation; Intestine, Small; Kidney; Liver; Male; Mutagenicity Tests; Mutagens; Polychlorinated Biphenyls; Quinolines; Rats; Rats, Inbred Strains; Salmonella typhimurium; Subcellular Fractions | 1987 |
A model system for studying covalent binding of food carcinogens MeIQx, MeIQ and IQ to DNA and protein.
Topics: Animals; Biotransformation; Carcinogens; DNA; Food Analysis; In Vitro Techniques; Microsomes, Liver; Mutagens; Protein Binding; Quinolines; Quinoxalines; Rats | 1988 |
Modulation of the mutagenic effects of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) in bacteria with rat-liver 9000 x g supernatant or monolayers of rat hepatocytes as an activation system.
Topics: Animals; Biotransformation; Cells, Cultured; Liver; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Quinolines; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1988 |
The hepatic conversion of some heterocyclic amines to bacterial mutagens is modified by dietary fat and cholesterol.
Topics: Animals; Biotransformation; Cattle; Cholesterol, Dietary; Dietary Fats; Hot Temperature; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1987 |
Effect of tryptamine on the mutagenic activity of 2-amino-3-methylimidazo(4,5-f) quinoline (IQ) and related azaarenes in the Ames test.
Topics: Animals; Aroclors; Biotransformation; Chlorodiphenyl (54% Chlorine); Cytosol; Enzyme Induction; In Vitro Techniques; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Species Specificity; Tryptamines | 1987 |
Mutagenic and carcinogenic heterocyclic amines in Chinese cooked foods.
Topics: China; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cooking; Diet; Food Analysis; Heterocyclic Compounds; Imidazoles; Mutagenicity Tests; Mutagens; Mutation; Neoplasms; Quinolines; Quinoxalines | 1988 |
Metabolic conversion of IQ and MeIQ to bacterial mutagens.
Topics: Acetyl Coenzyme A; Animals; Biotransformation; Ellipticines; Indazoles; Male; Methimazole; Microsomes, Liver; Mutagens; Quinolines; Rats; Rats, Inbred Strains; Salmonella typhimurium; Tryptamines; Tyramine | 1986 |
Comparative genotoxic effects of IQ and MeIQ in Salmonella typhimurium and cultured mammalian cells.
Topics: Animals; Aroclors; Biotransformation; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cricetinae; Cricetulus; DNA Damage; DNA Repair; Fibroblasts; Liver; Lung; Male; Mutagenicity Tests; Quinolines; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sister Chromatid Exchange | 1987 |
Fluorometric detection of 2-amino-3-methylimidazo[4,5-f]quinoline, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline and their N-acetylated metabolites excreted by the rat.
Topics: Acetylation; Animals; Cytosol; Fluorometry; Liver; Male; Mutagens; Quinolines; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1987 |
Detection of IQ-type heterocyclic amines in dialysis fluid of uremic patients treated by peritoneal dialysis.
Topics: Adult; Female; Humans; Male; Middle Aged; Mutagens; Peritoneal Dialysis, Continuous Ambulatory; Quinolines; Quinoxalines; Uremia | 1987 |
Induction of unscheduled DNA synthesis in rat and hamster hepatocytes by cooked food mutagens.
Topics: Animals; Biotransformation; Carbolines; Cricetinae; DNA; DNA Repair; Liver; Male; Mesocricetus; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Chemistry of mutagens and carcinogens in broiled food.
Topics: Carcinogens; Food Contamination; Hot Temperature; Humans; Mutagens; Quinolines | 1986 |
Carcinogenicity in mice and rats of heterocyclic amines in cooked foods.
Topics: Animals; Carbolines; Carcinogens; Female; Food Contamination; Heterocyclic Compounds; Hot Temperature; Imidazoles; Male; Mice; Neoplasms, Experimental; Quinolines; Rats | 1986 |
Analysis of mutagens from cooked foods by directly combined liquid chromatography-mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Fishes; Food Analysis; Food Contamination; Hot Temperature; Mass Spectrometry; Meat; Mutagens; Quinolines | 1986 |
Synthesis and radiolabeling of heterocyclic food mutagens.
Topics: Animals; Cattle; Food Analysis; Food Contamination; Meat; Mutagens; Quinolines; Tritium | 1986 |
Mutagen formation in a model beef supernatant fraction. IV. Properties of the system.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Hot Temperature; Meat; Models, Chemical; Mutagenicity Tests; Mutagens; Phosphocreatine; Quinolines | 1986 |
Induction of hepatocellular carcinoma and highly metastatic squamous cell carcinomas in the forestomach of mice by feeding 2-amino-3,4-dimethylimidazo[4,5-f]quinoline.
Topics: Animals; Carcinoma, Squamous Cell; Female; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Mutagens; Neoplasm Metastasis; Quinolines; Sex Factors; Stomach Neoplasms | 1986 |
Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Carcinoma, Squamous Cell; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Stomach Neoplasms | 1985 |
Mammalian cell DNA damage by some heterocyclic food mutagens is correlated with their potency in the Ames test.
Topics: 2-Acetylaminofluorene; Animals; DNA; Food Analysis; Food Handling; Mice; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella typhimurium | 1985 |
Activation of the food mutagens IQ and MeIQ by hepatic S9 fractions derived from various species.
Topics: Animals; Aroclors; Biotransformation; Chlorodiphenyl (54% Chlorine); Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mutagenicity Tests; Mutagens; Quinolines; Rats; Rats, Inbred Strains; Salmonella typhimurium; Species Specificity | 1985 |
Stable isotope dilution quantification of mutagens in cooked foods by combined liquid chromatography-thermospray mass spectrometry.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cooking; Fishes; Food Analysis; Hot Temperature; Mass Spectrometry; Meat; Mutagens; Quinolines; Salmon | 1986 |
Mutagenic activation of IQ and Me-IQ by liver and lung microsomes from rabbit and mouse, and with isolated lung cells from the rabbit.
Topics: Animals; Biotransformation; Carbolines; Cytochrome P-450 CYP1A2; Cytochromes; In Vitro Techniques; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes; Microsomes, Liver; Mutagens; Quinolines; Rabbits | 1986 |
Autoradiographic distribution of 14C-labeled 3H-imidazo[4,5-f]quinoline-2-amines in mice.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Endocrine Glands; Female; Fetus; Lymphoid Tissue; Male; Melanins; Mice; Mice, Inbred Strains; Mutagens; Pregnancy; Quinolines; Tissue Distribution | 1985 |
Genotoxicity of the cooked-food mutagens IQ and MeIQ in primary cultures of rat, hamster, and guinea pig hepatocytes.
Topics: Animals; Cricetinae; DNA; DNA Repair; Guinea Pigs; Liver; Male; Mesocricetus; Mutagens; Quinolines; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
A balance study of 14C-labelled 3H-imidazo[4,5-f]quinolin-2-amines (IQ and MeIQ) in rats.
Topics: Animals; Bile; Breath Tests; Carbon Radioisotopes; Feces; Female; Isotope Labeling; Male; Mutagenicity Tests; Quinolines; Rats; Rats, Inbred Strains | 1984 |
Isolation and characterization of new mutagens from fried ground beef.
Topics: Hot Temperature; Mass Spectrometry; Meat; Mutagens; Nitrites; Quinolines | 1984 |
DNA-binding of IQ, Me-IQ and Me-IQx, strong mutagens found in broiled foods.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cooking; DNA; Hot Temperature; Mutagens; Quinolines; Quinoxalines; Spectrophotometry; Thymus Gland | 1982 |
Heterocyclic aromatic amine content of selected beef flavors.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Creatine; Creatinine; Dose-Response Relationship, Drug; Flavoring Agents; Imidazoles; Linear Models; Meat Products; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Salmonella typhimurium | 1994 |
Possible occurrence of P450 related to P450 HFLb in extrahepatic tissues of human fetuses and its contribution to metabolic activation of promutagens.
Topics: Adrenal Glands; Aflatoxin B1; Benzo(a)pyrene; Biotransformation; Cytochrome P-450 Enzyme System; Fetus; Humans; Kidney; Liver; Lung; Mutagens; Quinolines | 1994 |
Binding of mutagenic heterocyclic amines by intestinal and lactic acid bacteria.
Topics: Amines; Bifidobacterium; Biotransformation; Carbolines; Chromatography, High Pressure Liquid; Cooking; Food Contamination; Heterocyclic Compounds; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Intestines; Lactobacillus; Meat; Mutagenicity Tests; Mutagens; Quinolines; Regression Analysis | 1994 |
Modifying actions of solvent extracts from fruit and vegetable residues on 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoxaline (MeIQx) induced mutagenesis in Salmonella typhimurium TA 98.
Topics: Antimutagenic Agents; Chlorophyll; Dose-Response Relationship, Drug; Fruit; Mutagenicity Tests; Mutagens; Plant Extracts; Polysaccharides; Quinolines; Salmonella typhimurium; Solvents; Species Specificity; Vegetables | 1995 |
Simultaneous expression of human CYP3A7 and N-acetyltransferase in Chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines.
Topics: Amines; Animals; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Carcinogens; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Gene Expression; Gene Transfer Techniques; Humans; Quinolines; Quinoxalines | 1995 |
Effects of Maillard reaction products on mutagen formation in boiled pork juice.
Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Maillard Reaction; Meat; Mutagens; Picolines; Pyrazines; Quinolines; Quinoxalines; Swine; Thiophenes | 1995 |
Suppressing effects of S phase post-treatment with carbolines on sister-chromatid exchanges induced by mitomycin C in Chinese hamster cells.
Topics: Animals; Antimutagenic Agents; Carbolines; CHO Cells; Cricetinae; Mitomycin; Mutagens; Quinolines; Quinoxalines; S Phase; Sister Chromatid Exchange | 1993 |
Species differences in metabolism of heterocyclic aromatic amines, human exposure, and biomonitoring.
Topics: Animals; Carcinogens, Environmental; Environmental Exposure; Food Contamination; Male; Molecular Structure; Monitoring, Physiologic; Mutagens; Quinolines; Rats; Rats, Sprague-Dawley; Species Specificity | 1994 |
Metabolic activation of heterocyclic amine food mutagens in the mammary gland of lactating Fischer 344 rats.
Topics: Acetyl-CoA C-Acetyltransferase; Amines; Amino Acyl-tRNA Synthetases; Animals; Autoradiography; Biotransformation; DNA; Female; Food; Heterocyclic Compounds; Imidazoles; Lactation; Liver; Mammary Glands, Animal; Microsomes; Mutagenicity Tests; Mutagens; Quinolines; Rats; Rats, Inbred F344 | 1994 |
In vitro effect of vegetable and fruit juices on the mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Topics: Animals; Antimutagenic Agents; Beverages; Biotransformation; Fruit; In Vitro Techniques; Male; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Vegetables | 1994 |
Separation of 32P-labelled nucleoside 3',5'-bisphosphate adducts by HPLC.
Topics: Animals; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Coal Tar; DNA; DNA Damage; Evaluation Studies as Topic; Female; Fluorenes; Humans; In Vitro Techniques; Male; Mice; Phosphorus Radioisotopes; Quinolines; Rats | 1993 |
Hydrogen peroxide supports human and rat cytochrome P450 1A2-catalyzed 2-amino-3-methylimidazo[4,5-f]quinoline bioactivation to mutagenic metabolites: significance of cytochrome P450 peroxygenase.
Topics: Animals; Biotransformation; Catalysis; Cytochrome P-450 CYP1A2; Enzyme Activation; Humans; Hydrogen Peroxide; Male; Microsomes, Liver; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens; Quinolines; Rats; Rats, Sprague-Dawley; Salmonella typhimurium | 1997 |
Inhibition of the genotoxic effects of heterocyclic amines in human derived hepatoma cells by dietary bioantimutagens.
Topics: Acrolein; Amines; Antimutagenic Agents; Benzaldehydes; Caffeine; Carbolines; Carcinoma, Hepatocellular; Coumarins; DNA Repair; Heterocyclic Compounds; Humans; Hydrolyzable Tannins; Imidazoles; Micronucleus Tests; Mutagens; Quinolines; Tumor Cells, Cultured | 1997 |
In vivo genotoxicity of heterocyclic amines detected by a modified alkaline single cell gel electrophoresis assay in a multiple organ study in the mouse.
Topics: Amines; Animals; Brain; Carbolines; DNA Damage; Electrophoresis; Imidazoles; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Mutagens; Quinolines; Quinoxalines; Stomach | 1997 |
Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.
Topics: Arylamine N-Acetyltransferase; Biotransformation; Breast; Carcinogens; Cells, Cultured; DNA Adducts; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Imidazoles; Polymorphism, Restriction Fragment Length; Quinolines | 1998 |
Antimutagenicity and the influence of physical factors in binding Lactobacillus gasseri and Bifidobacterium longum cells to amino acid pyrolysates.
Topics: Amino Acids; Antimutagenic Agents; Bifidobacterium; Binding Sites; Carbolines; Cell Wall; Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Imidazoles; Lactobacillus; Mutagens; Periodic Acid; Quinolines; Time Factors; Trichloroacetic Acid | 1998 |
Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells.
Topics: Amines; Animals; Arylamine N-Acetyltransferase; Carbolines; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Survival; CHO Cells; Cricetinae; Heterocyclic Compounds; Humans; Imidazoles; Liver Neoplasms; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella; Tumor Cells, Cultured | 1999 |
Modification of mutagenic activities of pro-mutagens by glyco-ursodeoxycholic acid in the Ames assay.
Topics: Anthracenes; Antimutagenic Agents; Benzo(a)pyrene; Bile; Carbolines; Humans; Mutagenicity Tests; Mutagens; Quinolines; Salmonella typhimurium; Ursodeoxycholic Acid | 1999 |
Antimutagenic activities of various lactic acid bacteria against food mutagens: heterocyclic amines.
Topics: Amines; Animals; Bifidobacterium; Colony Count, Microbial; Fermentation; Food Contamination; Heterocyclic Compounds; Imidazoles; Lactobacillus; Milk; Mutagenicity Tests; Mutagens; Quinolines; Streptococcus | 2002 |
Functional characterization of four allelic variants of human cytochrome P450 1A2.
Topics: Alleles; Amino Acid Sequence; Animals; Cytochrome P-450 CYP1A2; Escherichia coli; Genetic Variation; Humans; Hydroxylation; Kinetics; Lac Operon; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagenicity Tests; Protein Structure, Secondary; Quinolines; Rats; Recombinant Proteins | 2004 |
Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.
Topics: Acetonitriles; Amines; Buffers; Carbolines; Chromatography, Liquid; Formates; Harmine; Heterocyclic Compounds; Hydrogen-Ion Concentration; Imidazoles; Quinolines; Quinoxalines; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Selected heterocyclic amines.
Topics: Amines; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Environmental Exposure; Female; Government Regulation; Guidelines as Topic; Heterocyclic Compounds; Humans; Imidazoles; Macaca fascicularis; Male; Mice; Models, Biological; Quinolines; Quinoxalines; Rats; United States | 2004 |
Selective dopaminergic neurotoxicity of three heterocyclic amine subclasses in primary rat midbrain neurons.
Topics: Amines; Animals; Carbolines; Dopaminergic Neurons; Dose-Response Relationship, Drug; Harmine; Heterocyclic Compounds, 3-Ring; Mesencephalon; Molecular Structure; Nerve Degeneration; Neurites; Neurons; Primary Cell Culture; Quinolines; Quinoxalines; Rats | 2018 |