Page last updated: 2024-09-03

2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid and kainic acid

2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid has been researched along with kainic acid in 2 studies

Compound Research Comparison

Studies
(2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid)
Trials
(2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid)
Recent Studies (post-2010)
(2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid)
Studies
(kainic acid)
Trials
(kainic acid)
Recent Studies (post-2010) (kainic acid)
5009,54031,775

Protein Interaction Comparison

ProteinTaxonomy2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid (IC50)kainic acid (IC50)
Glutamate receptor 1Rattus norvegicus (Norway rat)4.2857
Glutamate receptor 2Rattus norvegicus (Norway rat)4.2857
Glutamate receptor 3Rattus norvegicus (Norway rat)4.2857
Glutamate receptor 4Rattus norvegicus (Norway rat)4.2857
Glutamate receptor ionotropic, kainate 1Rattus norvegicus (Norway rat)0.0126
Glutamate receptor ionotropic, kainate 1Homo sapiens (human)0.077
Glutamate receptor ionotropic, kainate 2Rattus norvegicus (Norway rat)0.0126
Glutamate receptor ionotropic, kainate 3Rattus norvegicus (Norway rat)0.0126
Glutamate receptor ionotropic, kainate 4Rattus norvegicus (Norway rat)0.0126
Glutamate receptor ionotropic, kainate 2Homo sapiens (human)0.077
Glutamate receptor ionotropic, kainate 3Homo sapiens (human)0.077
Glutamate receptor ionotropic, kainate 4Homo sapiens (human)0.077
Glutamate receptor ionotropic, kainate 5Homo sapiens (human)0.077
Glutamate receptor ionotropic, kainate 5Rattus norvegicus (Norway rat)0.0126

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bregnedal, P; Brehm, L; Bøgesø, KP; Ebert, B; Frederiksen, K; Hansen, JJ; Krogsgaard-Larsen, P; Lenz, S1
Brehm, L; Ebert, B; Falch, E; Johansen, TN; Krogsgaard-Larsen, P; Mikkelsen, I; Nielsen, B; Skjaerbaek, N; Stensbøl, TB1

Other Studies

2 other study(ies) available for 2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid and kainic acid

ArticleYear
Resolution, absolute stereochemistry, and pharmacology of the S-(+)- and R-(-)-isomers of the apparent partial AMPA receptor agonist (R,S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R,S)-APPA].
    Journal of medicinal chemistry, 1994, Apr-01, Volume: 37, Issue:7

    Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Crystallography, X-Ray; Dizocilpine Maleate; Glycine; In Vitro Techniques; Isoxazoles; Kainic Acid; Rats; Receptors, AMPA; Stereoisomerism

1994
Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships.
    Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallography, X-Ray; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Furans; In Vitro Techniques; Isoxazoles; Photoaffinity Labels; Photochemistry; Rats; Receptors, AMPA; Stereoisomerism; Structure-Activity Relationship

1998