2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 3 studies
| Studies (2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid) | Trials (2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid) | Recent Studies (post-2010) (2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid) | Studies (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) | Trials (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) | Recent Studies (post-2010) (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 2,899 | 11 | 609 |
| 5 | 0 | 0 | 24 | 0 | 3 |
| Protein | Taxonomy | 2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid (IC50) | alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.157 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.1765 | |
| Glutamate receptor 1 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 2 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.1353 | |
| Glutamate receptor 4 | Mus musculus (house mouse) | 0.04 | |
| Glutamate receptor 3 | Mus musculus (house mouse) | 0.04 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bregnedal, P; Brehm, L; Bøgesø, KP; Ebert, B; Frederiksen, K; Hansen, JJ; Krogsgaard-Larsen, P; Lenz, S | 1 |
| Ebert, B; Krogsgaard-Larsen, P; Lenz, SM; Lund, TM; Madsen, U | 1 |
| Brehm, L; Ebert, B; Falch, E; Johansen, TN; Krogsgaard-Larsen, P; Mikkelsen, I; Nielsen, B; Skjaerbaek, N; Stensbøl, TB | 1 |
3 other study(ies) available for 2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
| Article | Year |
|---|---|
Resolution, absolute stereochemistry, and pharmacology of the S-(+)- and R-(-)-isomers of the apparent partial AMPA receptor agonist (R,S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R,S)-APPA].
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Crystallography, X-Ray; Dizocilpine Maleate; Glycine; In Vitro Techniques; Isoxazoles; Kainic Acid; Rats; Receptors, AMPA; Stereoisomerism | 1994 |
Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Membrane; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Isoxazoles; Male; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Structure-Activity Relationship | 1994 |
Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallography, X-Ray; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Furans; In Vitro Techniques; Isoxazoles; Photoaffinity Labels; Photochemistry; Rats; Receptors, AMPA; Stereoisomerism; Structure-Activity Relationship | 1998 |