2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and phosphorus radioisotopes

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with phosphorus radioisotopes in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, IS; Kim, SB; Nagao, M; Nagaoka, H; Nukaya, H; Ochiai, M; Sugimura, T; Tada, A; Tanaka, Y; Wakabayashi, K1
Herzog, CR; Schut, HA1
Buonarati, MH; Davis, JC; Felton, JS; Gledhill, BL; Turteltaub, KW; Vogel, JS1
Bartsch, H; Castegnaro, M; Friesen, M; Garren, L; Hautefeuille, A; Kadlubar, F; Malaveille, C; Peluso, M; Vineis, P1
Fukutome, K; Nagao, M; Ochiai, M; Sugimura, T; Wakabayashi, K; Watanabe, S1
Blum, M; Fasshauer, I; Kerdar, RS; Meyer, UA; Probst, M; Wild, D1
Davis, CD; Nouso, K; Roller, PP; Schut, HA; Snyderwine, EG1
Felton, JS; Frantz, C; McManus, M; Turteltaub, KW; Vogel, JS1
Gustafsson, JA; Möller, L; Wohlin, P; Zeisig, M1
Marsch, GA; Mauthe, RJ; Turteltaub, KW1
Brockstedt, U; Ito, N; Marquardt, H; Pfau, W; Shirai, T1

Reviews

1 review(s) available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and phosphorus radioisotopes

ArticleYear
Assessment of the DNA adduction and pharmacokinetics of PhIP and MeIOx in rodents at doses approximating human exposure using the technique of accelerator mass spectrometry (AMS) and 32P-postlabeling.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Animals; Carcinogens; DNA Adducts; Humans; Imidazoles; Mass Spectrometry; Mutagens; Neoplasms; Phosphorus Radioisotopes; Quinoxalines; Radioisotope Dilution Technique; Rodentia

1995

Other Studies

10 other study(ies) available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and phosphorus radioisotopes

ArticleYear
Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine with 2'-deoxyguanosine and its phosphate esters.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:10

    Topics: Acetic Anhydrides; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Deoxyguanosine; Guanine; Imidazoles; Isotope Labeling; Magnetic Resonance Spectroscopy; Mutagens; Nucleotides; Phosphates; Phosphorus Radioisotopes; Pyridines; Spectrometry, Mass, Fast Atom Bombardment

1992
Formation of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in male Fischer-344 rats.
    Cancer letters, 1992, Dec-24, Volume: 67, Issue:2-3

    Topics: Animals; Colonic Neoplasms; DNA; Imidazoles; Male; Mutagens; Phosphorus Radioisotopes; Rats; Rats, Inbred F344

1992
DNA dosimetry following carcinogen exposure using accelerator mass spectrometry and 32P-postlabeling.
    Progress in clinical and biological research, 1991, Volume: 372

    Topics: Animals; Binding Sites; Carcinogens; DNA; DNA Damage; Humans; Imidazoles; Mass Spectrometry; Mice; Phosphorus Radioisotopes; Quinoxalines

1991
32P Postlabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) as a major DNA-damaging agent.
    Carcinogenesis, 1991, Volume: 12, Issue:4

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA; DNA Damage; Humans; Imidazoles; Mutagens; Nicotiana; Nucleotides; Phosphorus Radioisotopes; Plants, Toxic; Smoking

1991
Detection of guanine-C8-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine adduct as a single spot on thin-layer chromatography by modification of the 32P-postlabeling method.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:2

    Topics: Animals; Autoradiography; Carcinogens; Chromatography, Thin Layer; Deoxyguanosine; DNA; Imidazoles; Lung; Male; Mutagens; Phosphorus Radioisotopes; Rats; Rats, Inbred F344

1994
32P-postlabelling studies on the DNA adducts of the food mutagens/carcinogens IQ and PhIP--adduct formation in a chemical system, and by rat and human metabolism.
    IARC scientific publications, 1993, Issue:124

    Topics: Animals; Arylamine N-Acetyltransferase; Biotransformation; Carcinogens; Cell Line; DNA; DNA Damage; Humans; Imidazoles; In Vitro Techniques; Male; Mutagens; Phosphorus Radioisotopes; Quinolines; Rats; Rats, Inbred F344; Ultraviolet Rays

1993
32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
    Carcinogenesis, 1993, Volume: 14, Issue:7

    Topics: Animals; Autoradiography; Chromatography, High Pressure Liquid; DNA; DNA Damage; Haplorhini; Imidazoles; Liver; Mutagens; Phosphorus Radioisotopes; Polynucleotides; Quinolines; Quinoxalines

1993
32-P-HPLC analysis of DNA adducts formed in vitro and in vivo by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline, utilizing an improved adduct enrichment procedure.
    Chemical research in toxicology, 1996, Volume: 9, Issue:6

    Topics: Animals; Butanols; Carcinogens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA Adducts; Imidazoles; Isotope Labeling; Male; Mutagens; Phosphorus Radioisotopes; Quinoxalines; Rats; Rats, Wistar

1996
Improved high-performance liquid chromatography analysis of 32P-postlabeled 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adducts using in-line precolumn purification.
    Journal of chromatography. B, Biomedical applications, 1996, Apr-26, Volume: 679, Issue:1-2

    Topics: Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA; DNA Adducts; Imidazoles; Mice; Micrococcal Nuclease; Mutagens; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Reproducibility of Results; Sensitivity and Specificity; Thymus Gland

1996
Pancreatic DNA adducts formed in vitro and in vivo by the food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA alphaC).
    Mutation research, 1997, Aug-01, Volume: 378, Issue:1-2

    Topics: Animals; Carbolines; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diet; DNA Adducts; Imidazoles; Liver; Male; Mutagens; Organ Culture Techniques; Pancreas; Phosphorus Radioisotopes; Rats; Rats, Inbred F344; Rats, Wistar

1997