2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with deoxyguanosine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, IS; Kim, SB; Nagao, M; Nagaoka, H; Nukaya, H; Ochiai, M; Sugimura, T; Tada, A; Tanaka, Y; Wakabayashi, K | 1 |
| Andersson, R; Dragsted, L; Frandsen, H; Grivas, S; Larsen, JC | 1 |
| Fukutome, K; Nagao, M; Ochiai, M; Sugimura, T; Wakabayashi, K; Watanabe, S | 1 |
| Boobis, AR; Crosbie, SJ; Gooderham, NJ | 1 |
| Frandsen, H | 1 |
| Feng, Y; Fretland, AJ; Hein, DW | 1 |
| Amin, S; Chae, YH; Desai, D; El-Bayoumy, K; Fiala, E; Rosa, JG; Williams, LK | 1 |
| Boobis, AR; Bowey, EA; Edwards, AJ; Gooderham, NJ; Gray, S; Lake, BG; Murray, S; Springall, C; Williamson, G | 1 |
| Kawanishi, S; Murata, M | 1 |
| Bartlet-Jones, M; Boobis, AR; Edwards, RJ; Fang, M; Murray, S; Taylor, GW | 1 |
| Fukushima, S; Furukawa, F; Hirose, M; Imaida, K; Iwai, S; Kishida, H; Morimura, K; Nakae, D; Shirai, T; Tatematsu, M; Tsuda, H; Tsukamoto, T; Uehara, N; Wanibuchi, H | 1 |
| Bonala, R; Iden, CR; Johnson, F; Torres, MC | 1 |
| Goodenough, AK; Schut, HA; Turesky, RJ | 1 |
| Arquier, D; Canlet, C; Debrauwer, L; Jamin, EL; Rathahao, E; Tulliez, J | 1 |
| Bessette, EE; Goodenough, AK; Kadlubar, FF; Pinto, S; Spivack, SD; Turesky, RJ; Wang, T | 1 |
| Amin, S; El-Bayoumy, K; Geacintov, NE; Kolbanovskiy, A; Kolbanovskiy, M; Kropachev, K; Krzeminski, J; Reeves, D; Yun, BH | 1 |
| Bosland, MC; Chen, JX; Lee, MJ; Li, G; Liu, A; Reuhl, K; Suh, N; Wang, H; Yang, CS | 1 |
17 other study(ies) available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and deoxyguanosine
| Article | Year |
|---|---|
Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine with 2'-deoxyguanosine and its phosphate esters.
Topics: Acetic Anhydrides; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Deoxyguanosine; Guanine; Imidazoles; Isotope Labeling; Magnetic Resonance Spectroscopy; Mutagens; Nucleotides; Phosphates; Phosphorus Radioisotopes; Pyridines; Spectrometry, Mass, Fast Atom Bombardment | 1992 |
Reaction of the N2-acetoxy derivative of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) with 2'-deoxyguanosine and DNA. Synthesis and identification of N2-(2'-deoxyguanosin-8-yl)-PhIP.
Topics: Animals; Deoxyguanosine; DNA; Imidazoles; Male; Mutagens; Rats; Rats, Inbred Strains | 1992 |
Detection of guanine-C8-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine adduct as a single spot on thin-layer chromatography by modification of the 32P-postlabeling method.
Topics: Animals; Autoradiography; Carcinogens; Chromatography, Thin Layer; Deoxyguanosine; DNA; Imidazoles; Lung; Male; Mutagens; Phosphorus Radioisotopes; Rats; Rats, Inbred F344 | 1994 |
Analysis of the N-(deoxyguanosin-8-yl) adduct of the food derived carcinogen PhIP using capillary electrophoresis.
Topics: Carbon Radioisotopes; Deoxyguanosine; Electrophoresis, Capillary; Imidazoles; Spectrophotometry, Ultraviolet | 1997 |
Excretion of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline, PhIP-dG, PhIP-DNA and DiMeIQx-DNA from the rat.
Topics: Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Feces; Imidazoles; Male; Quinoxalines; Rats; Rats, Wistar; Time Factors | 1997 |
DNA adduct levels in rapid and slow acetylator inbred rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Topics: Animals; Arylamine N-Acetyltransferase; Carcinogens, Environmental; Deoxyguanosine; DNA Adducts; Imidazoles; Male; Mutagens; Phenotype; Polymorphism, Genetic; Rats; Rats, Inbred F344; Rats, Inbred WKY; Tissue Distribution | 1997 |
The effects of 1-nitropyrene, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene on 8-hydroxy-2'-deoxyguanosine levels in the rat mammary gland and modulation by dietary 1,4-phenylenebis(methylene) selenocyanate.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Deoxyguanosine; Diet; DNA; Female; Imidazoles; Mammary Glands, Animal; Organoselenium Compounds; Pyrenes; Rats; Rats, Inbred Strains | 2000 |
Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man.
Topics: Adult; Biomarkers; Biotransformation; Brassica; Caffeine; Carcinogens; Cytochrome P-450 CYP1A2; Deoxyguanosine; DNA; Humans; Imidazoles; Lymphocytes; Male; Meat; Middle Aged; Quinoxalines | 2001 |
Oxidation of 5'-site guanine at GG and GGG sequences induced by a metabolite of carcinogenic heterocyclic amine PhIP in the presence of Cu(II) and NADH.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cattle; Copper; Deoxyguanosine; DNA; DNA Damage; Guanine; Imidazoles; NAD; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Spectrophotometry, Ultraviolet | 2002 |
Urinary N2-(2'-deoxyguanosin-8-yl)PhIP as a biomarker for PhIP exposure.
Topics: Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; Imidazoles; Male; Rabbits; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2004 |
Existence of a threshold for induction of aberrant crypt foci in the rat colon with low doses of 2-amino-1-methyl-6-phenolimidazo[4,5-b]pyridine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Colon; Colonic Neoplasms; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Imidazoles; Male; Mutagenicity Tests; Mutagens; No-Observed-Adverse-Effect Level; Precancerous Conditions; Rats; Rats, Inbred F344 | 2004 |
Synthesis of the PhIP adduct of 2'-deoxyguanosine and its incorporation into oligomeric DNA.
Topics: Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; Food; Imidazoles; Molecular Structure; Mutagens; Spectrometry, Mass, Electrospray Ionization | 2006 |
Novel LC-ESI/MS/MS(n) method for the characterization and quantification of 2'-deoxyguanosine adducts of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by 2-D linear quadrupole ion trap mass spectrometry.
Topics: Animals; Carcinogens; Chromatography, Liquid; Colon; Deoxyguanosine; Diet; DNA Adducts; Female; Imidazoles; Kinetics; Liver; Molecular Structure; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry; Time Factors | 2007 |
New insights in the formation of deoxynucleoside adducts with the heterocyclic aromatic amines PhIP and IQ by means of ion trap MSn and accurate mass measurement of fragment ions.
Topics: Chromatography, Liquid; Deoxyguanosine; Imidazoles; Mass Spectrometry; Molecular Weight; Quinolines | 2007 |
Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry.
Topics: Adult; Aged; Aged, 80 and over; Aminobiphenyl Compounds; Carcinogens; Deoxyguanosine; DNA Adducts; Female; Humans; Imidazoles; Male; Middle Aged; Saliva; Smoking; Tandem Mass Spectrometry | 2010 |
Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene.
Topics: Animals; Benzo(a)pyrene; Chromatography, High Pressure Liquid; Chrysenes; Deoxyguanosine; DNA Adducts; DNA Repair; HeLa Cells; Humans; Imidazoles; Mass Spectrometry; Oligonucleotides; Rats | 2011 |
Dietary tocopherols inhibit PhIP-induced prostate carcinogenesis in CYP1A-humanized mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Cyclooxygenase 2; Cytochrome P-450 CYP1A2; Deoxyguanosine; Diet; Disease Models, Animal; Humans; Imidazoles; Ki-67 Antigen; Male; Mice, Transgenic; NF-E2-Related Factor 2; Phosphorylation; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Tocopherols; Tyrosine | 2016 |