2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with benzo(a)pyrene in 38 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.63) | 18.7374 |
1990's | 5 (13.16) | 18.2507 |
2000's | 16 (42.11) | 29.6817 |
2010's | 15 (39.47) | 24.3611 |
2020's | 1 (2.63) | 2.80 |
Authors | Studies |
---|---|
Burgess, WM; Huggett, A; McManus, ME; Quattrochi, LC; Tukey, RH; Veronese, ME | 1 |
Felton, JS; Fuscoe, JC; Healy, SK; Shen, NH; Wu, R | 1 |
Chae, YH; el-Bayoumy, K; Hecht, SS; Kurtzke, C; Reddy, B; Rivenson, A; Upadhyaya, P | 1 |
Arai, H; Degawa, M; Hashimoto, Y; Matsuda, K | 1 |
Leucht, U; Pool-Zobel, BL | 1 |
Catterall, F; Clifford, MN; Copeland, E; Ioannides, C | 1 |
Belloir, C; Guyonnet, D; Le Bon, AM; Siess, MH; Suschetet, M | 1 |
Grover, PL; Hewer, A; Martin, FL; Muir, GH; Phillips, DH; Williams, JA | 1 |
Coxhead, JM; Cupid, BC; Garner, RC; Lightfoot, TJ; Nicholson, S | 1 |
Fujita, K; Kamataki, T; Muto, S; Yamazaki, Y | 1 |
de Boer, JG | 1 |
Ambrosone, CB; Fares, M; Gorlewska-Roberts, K; Green, B; Kadlubar, FF | 1 |
Cavin, C; Constable, A; Holzhaeuser, D; Huber, WW; Scharf, G; Schilter, B | 1 |
Chakraborty, A; Ecker, S; Kassie, F; Knasmüller, S; Lhoste, E; Mohn, G; Uhl, M | 1 |
Bader, A; Stahl, F; Wilkening, S | 1 |
Cooney, GT; de Boer, JG; Holcroft, J | 1 |
He, XY; Hong, JY; Wang, SL | 1 |
Cross, AJ; Hayes, RB; Kulldorff, M; Peters, U; Pinsky, PF; Rothman, N; Sinha, R; Weissfeld, JL | 1 |
Andriole, GL; Cross, AJ; Hayes, RB; Kirsh, VA; Peters, U; Reding, D; Sinha, R | 1 |
Bradley, C; Chandrasekharan, MB; Mernaugh, RL; Parl, FF; Roodi, N; Sun, ZW; van der Meer, R; Yan, H | 1 |
Forero, A; Hewitt, R; Luncsford, PJ; Martin, FL | 1 |
Jones, KC; Llabjani, V; Martin, FL; Shore, RF; Thomas, GO; Walker, LA | 1 |
Chen, G; Douglas, GR; Gingerich, J; Soper, L; White, PA | 1 |
Amin, S; El-Bayoumy, K; Geacintov, NE; Kolbanovskiy, A; Kolbanovskiy, M; Kropachev, K; Krzeminski, J; Reeves, D; Yun, BH | 1 |
Dobnik, D; Filipič, M; Niderl, MH; Zegura, B | 1 |
Chow, WH; Cross, AJ; Daniel, CR; Graubard, BI; Hollenbeck, AR; Park, Y; Rothman, N; Sinha, R; Ward, MH | 1 |
Choudhary, S; Sood, S; Wang, HC | 1 |
Cross, AJ; Harper, G; Hartman, TJ; Laio, J; Lazarus, P; Lesko, SM; Miller, PE; Muscat, JE; Sinha, R; Zhu, J | 1 |
Audebert, M; Cravedi, JP; Debrauwer, L; Douki, T; Jamin, EL; Riu, A; Zalko, D | 1 |
Haza, AI; Morales, P | 1 |
Pluchino, LA; Wang, HC | 1 |
David, R; Ebbels, T; Gooderham, N | 1 |
Ferk, F; Filipič, M; Haas, O; Haslinger, E; Huber, WW; Knasmüller, S; Mai, S; Mikulits, W; Mišík, M; Tomc, J; Waldherr, M; Žegura, B | 1 |
Breznik, B; Filipič, M; Kamenšek, U; Kološa, K; Tomc, J; Turnšek, TL; Žegura, B | 1 |
David, RM; Gooderham, NJ | 1 |
Castaño, PR; Linseisen, J; Martínez Góngora, V; Matthes, KL; Rohrmann, S | 1 |
David, RM; Gooderham, NJ; Malik, DE | 1 |
Chatzi, K; Coke, BA; Coltman, NJ; Hodges, NJ; Lalor, PF; Schulz-Utermoehl, T; Shepherd, EL | 1 |
3 review(s) available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and benzo(a)pyrene
Article | Year |
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Protection by dietary compounds against mutation in a transgenic rodent.
Topics: Aflatoxin B1; Animals; Animals, Genetically Modified; Bacterial Proteins; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; Escherichia coli Proteins; Humans; Imidazoles; Lac Repressors; Mice; Mutagenesis; Mutagens; Mutation; Neoplasms; Rats; Repressor Proteins; Sex Characteristics; Species Specificity | 2001 |
Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Cells, Cultured; Coffee; Colorectal Neoplasms; Disease Models, Animal; Diterpenes; Enzyme Induction; Humans; Imidazoles | 2002 |
Dietary Heterocyclic Amine Intake and Colorectal Adenoma Risk: A Systematic Review and Meta-analysis.
Topics: Adenoma; Adult; Aged; Amines; Benzo(a)pyrene; Colorectal Neoplasms; Diet; Female; Heterocyclic Compounds; Humans; Imidazoles; Male; Meat; Middle Aged; Mutagens; Odds Ratio; Quinoxalines; Red Meat | 2019 |
1 trial(s) available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and benzo(a)pyrene
Article | Year |
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A prospective study of meat and meat mutagens and prostate cancer risk.
Topics: Aged; Benzo(a)pyrene; Cooking; Diet; Humans; Imidazoles; Male; Meat; Middle Aged; Mutagens; Prospective Studies; Prostatic Neoplasms; Quinoxalines; Risk Factors; Surveys and Questionnaires | 2005 |
34 other study(ies) available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and benzo(a)pyrene
Article | Year |
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Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
Topics: 2-Acetylaminofluorene; Adolescent; Adult; Aged; Benzo(a)pyrene; Cell Line; Child; Cytochrome P-450 Enzyme System; Food Contamination; Gene Expression; Humans; Hydroxylation; Imidazoles; Microsomes, Liver; Middle Aged; Quinolines; Quinoxalines | 1990 |
Base-change analysis of revertants of the hisD3052 allele in Salmonella typhimurium.
Topics: Aflatoxin B1; Aflatoxins; Base Composition; Base Sequence; Benzo(a)pyrene; Carcinogens; Cloning, Molecular; DNA, Bacterial; Food; Histidine; Imidazoles; Molecular Sequence Data; Mutagens; Operon; Quinolines; Salmonella typhimurium | 1988 |
Comparative tumorigenicity of benzo[a]pyrene, 1-nitropyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine administered by gavage to female CD rats.
Topics: Animals; Benzo(a)pyrene; Body Weight; Carcinogens; Environmental Pollutants; Female; Imidazoles; Mammary Neoplasms, Experimental; Mutagens; Pyrenes; Rats; Rats, Inbred Strains | 1995 |
Lead nitrate inhibits the induction of CYP1A mRNAs by aromatic amines but not by aryl hydrocarbons in the rat liver.
Topics: Animals; Base Sequence; Benzo(a)pyrene; beta-Naphthoflavone; Carbolines; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Imidazoles; Male; Methylcholanthrene; Microsomes, Liver; Oligonucleotide Probes; p-Aminoazobenzene; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1996 |
Induction of DNA damage by risk factors of colon cancer in human colon cells derived from biopsies.
Topics: Adult; Aged; Animals; Benzo(a)pyrene; Biopsy; Cells, Cultured; Colon; DNA; DNA Damage; Female; Humans; Hydrogen Peroxide; Imidazoles; Intestinal Mucosa; Lithocholic Acid; Male; Methylnitronitrosoguanidine; Middle Aged; Mutagenicity Tests; Mutagens; Quinolines; Rats; Risk Factors | 1997 |
Contribution of theafulvins to the antimutagenicity of black tea: their mechanism of action.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Benzo(a)pyrene; Carcinogens; Catechin; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Imidazoles; Male; Microsomes, Liver; N-Nitrosopyrrolidine; Nitrosamines; Oxazines; Phenols; Polyphenols; Quinolines; Rats; Rats, Wistar; Tea; Vitamin K | 1998 |
Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation.
Topics: Allium; Allyl Compounds; Animals; Benzo(a)pyrene; Cyclophosphamide; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfides; Dose-Response Relationship, Drug; Imidazoles; Liver Extracts; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Nitrosamines; Oxidoreductases; Propane; Rats; Rats, Wistar; Subcellular Fractions; Sulfides | 2000 |
Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; DNA; Gene Expression; Humans; Imidazoles; Male; Organ Culture Techniques; Prostatectomy; Prostatic Hyperplasia; Pyridines; Quinolines; RNA, Messenger | 2000 |
Analysis of DNA adducts by accelerator mass spectrometry in human breast tissue after administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and benzo[a]pyrene.
Topics: Aged; Benzo(a)pyrene; Biological Availability; Biotransformation; Breast; Breast Neoplasms; Carbon Radioisotopes; Carcinogens; DNA; DNA Adducts; Female; Humans; Imidazoles; Lymph Nodes; Mass Spectrometry; Middle Aged; Particle Accelerators | 2000 |
Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450.
Topics: Aflatoxin B1; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Beverages; Carcinogens; Catechin; Cell Membrane; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Kinetics; Mixed Function Oxygenases; Mutagenesis; NADPH-Ferrihemoprotein Reductase; Protein Binding; Salmonella typhimurium | 2001 |
Carcinogen-DNA adducts in human breast epithelial cells.
Topics: Adult; Aminobiphenyl Compounds; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; DNA Adducts; DNA Damage; Epithelial Cells; Female; Humans; Imidazoles; Milk, Human | 2002 |
Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells.
Topics: Animals; Antimutagenic Agents; Benzo(a)pyrene; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Flavonoids; Humans; Imidazoles; Mutagenicity Tests; Mutagens | 2003 |
Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties.
Topics: 7-Alkoxycoumarin O-Dealkylase; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; Cytochrome P-450 CYP1A1; Cytoskeleton; Dimethylnitrosamine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression; Hepatocytes; Humans; Imidazoles; Inactivation, Metabolic; Liver Neoplasms; Male; Middle Aged; Mutagens; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
The effect of dietary restriction on PhIP-induced mutation in the distal colon and B[a]P- and ENU-induced mutation in the liver of the rat.
Topics: Animals; Benzo(a)pyrene; Colon; Diet, Reducing; DNA; Ethylnitrosourea; Female; Imidazoles; Liver; Liver Neoplasms, Experimental; Male; Mutagens; Rats; Rats, Inbred F344; Rats, Mutant Strains; Sex Factors | 2004 |
Human cytochrome p450 2s1: lack of activity in the metabolic activation of several cigarette smoke carcinogens and in the metabolism of nicotine.
Topics: Animals; Baculoviridae; Benzo(a)pyrene; Biotransformation; Carcinogens; Cell Line; Cell Survival; CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Humans; Imidazoles; Insecta; Nicotiana; Nicotine; Nitrosamines; Oxygenases; Smoke | 2005 |
Meat, meat cooking methods and preservation, and risk for colorectal adenoma.
Topics: Adenoma; Aged; Benzo(a)pyrene; Carcinogens; Colorectal Neoplasms; Cooking; Diet; Female; Food Preservation; Humans; Imidazoles; Male; Meat; Middle Aged; Mutagens; Quinoxalines | 2005 |
Carcinogen-induced histone alteration in normal human mammary epithelial cells.
Topics: Aminobiphenyl Compounds; Benzo(a)pyrene; Biotinylation; Breast; Carcinogens; Cells, Cultured; Epithelial Cells; Female; Histones; Humans; Imidazoles; Immunoglobulin Variable Region; Peptide Library; Polychlorinated Dibenzodioxins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Enhanced micronucleus formation and modulation of BCL-2:BAX in MCF-7 cells after exposure to binary mixtures.
Topics: bcl-2-Associated X Protein; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P-450 Enzyme System; Drug Interactions; Estradiol; Gene Expression Regulation; Hexachlorocyclohexane; Humans; Imidazoles; Micronuclei, Chromosome-Defective; Micronucleus Tests; Proto-Oncogene Proteins c-bcl-2; Xenobiotics | 2007 |
Polybrominated diphenyl ether-associated alterations in cell biochemistry as determined by attenuated total reflection Fourier-transform infrared spectroscopy: a comparison with DNA-reactive and/or endocrine-disrupting agents.
Topics: Benzo(a)pyrene; Biochemical Phenomena; Cell Line, Tumor; DNA; Endocrine Disruptors; Halogenated Diphenyl Ethers; Humans; Imidazoles; Principal Component Analysis; Spectroscopy, Fourier Transform Infrared | 2009 |
Induction of lacZ mutations in MutaMouse primary hepatocytes.
Topics: Aminopyridines; Animals; Benzo(a)pyrene; Cells, Cultured; Cytochrome P-450 Enzyme System; Hepatocytes; Imidazoles; Lac Operon; Mice; Mice, Mutant Strains; Mutagenicity Tests; Mutagens; Mutation | 2010 |
Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene.
Topics: Animals; Benzo(a)pyrene; Chromatography, High Pressure Liquid; Chrysenes; Deoxyguanosine; DNA Adducts; DNA Repair; HeLa Cells; Humans; Imidazoles; Mass Spectrometry; Oligonucleotides; Rats | 2011 |
Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antioxidants; Benzo(a)pyrene; Cytoprotection; DNA Damage; Free Radical Scavengers; Hep G2 Cells; Humans; Imidazoles; Microbial Sensitivity Tests; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Quinolines; Rosmarinus; Salmonella typhimurium; tert-Butylhydroperoxide | 2011 |
Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinoma.
Topics: Benzo(a)pyrene; Carcinoma, Renal Cell; Cooking; Diet; Female; Humans; Imidazoles; Incidence; Male; Meat; Middle Aged; Mutagens; Polycyclic Compounds; Prospective Studies; Risk Factors | 2012 |
Dipyridamole intervention of breast cell carcinogenesis.
Topics: Apoptosis; Benzo(a)pyrene; Blotting, Western; Breast; Breast Neoplasms; Carcinogens; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Dipyridamole; DNA Damage; Female; Humans; Imidazoles; MAP Kinase Signaling System; Nitrosamines; Reactive Oxygen Species; Vasodilator Agents | 2014 |
Meat-related compounds and colorectal cancer risk by anatomical subsite.
Topics: Aged; Animals; Benzo(a)pyrene; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Cooking; Feeding Behavior; Female; Humans; Imidazoles; Logistic Models; Male; Meat; Meat Products; Middle Aged; Nitrates; Nitrites; Pennsylvania; Poultry; Quinoxalines; Rectal Neoplasms; Risk Factors; Surveys and Questionnaires | 2013 |
Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis.
Topics: Animals; Benzo(a)pyrene; Cell Line; Chromatography, High Pressure Liquid; Colorectal Neoplasms; DNA Adducts; Histones; Humans; Imidazoles; Intestinal Mucosa; Meat; Mice; Mutagenicity Tests; Phosphorylation; Tandem Mass Spectrometry | 2013 |
Spanish honeys protect against food mutagen-induced DNA damage.
Topics: Anticarcinogenic Agents; Benzo(a)pyrene; Cell Survival; Comet Assay; DNA Breaks; DNA Damage; Ericaceae; Food Contamination; Functional Food; Hep G2 Cells; Honey; Humans; Imidazoles; Liver Neoplasms; Models, Biological; Mutagens; N-Nitrosopyrrolidine; Phenols; Rosmarinus; Spain | 2013 |
Chronic exposure to combined carcinogens enhances breast cell carcinogenesis with mesenchymal and stem-like cell properties.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogenesis; Carcinogens; DNA Damage; Drug Synergism; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; MCF-7 Cells; NADPH Oxidases; Nitrosamines; ras Proteins; Reactive Oxygen Species; Signal Transduction | 2014 |
Synergistic and Antagonistic Mutation Responses of Human MCL-5 Cells to Mixtures of Benzo[a]pyrene and 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine: Dose-Related Variation in the Joint Effects of Common Dietary Carcinogens.
Topics: Benzo(a)pyrene; Carcinogens; Cell Line; Cell Line, Tumor; Cytochrome P-450 CYP1A1; DNA Damage; Humans; Imidazoles; Mutation; RNA, Messenger | 2016 |
Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?
Topics: Aflatoxin B1; Benzo(a)pyrene; Cell Line, Tumor; Dimethylnitrosamine; Humans; Hydrogen Peroxide; Imidazoles; Inactivation, Metabolic; Liver; Mutagenicity Tests; Mutagens; Quinolines; Reactive Oxygen Species; Tumor Suppressor Protein p53 | 2018 |
Adipose tissue stem cell-derived hepatic progenies as an in vitro model for genotoxicity testing.
Topics: Adipose Tissue; Aflatoxin B1; Benzo(a)pyrene; Cell Differentiation; Cell Line; Comet Assay; Enzymes; Female; Hep G2 Cells; Humans; Imidazoles; Liver; Mesenchymal Stem Cells; Mutagenicity Tests | 2018 |
Dose-dependent synergistic and antagonistic mutation responses of binary mixtures of the environmental carcinogen benzo[a]pyrene with food-derived carcinogens.
Topics: Acrylamide; Benzo(a)pyrene; Carcinogens; Carcinogens, Environmental; Cell Line; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Epoxy Compounds; Food; Humans; Imidazoles; Mutagenesis; Mutagenicity Tests; Mutagens; Mutation | 2018 |
Interleukin-6 selectively induces drug metabolism to potentiate the genotoxicity of dietary carcinogens in mammary cells.
Topics: Benzo(a)pyrene; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cytochrome P-450 CYP1B1; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Inflammation; Interleukin-6; MCF-7 Cells; MicroRNAs | 2019 |
Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies.
Topics: 4-Nitroquinoline-1-oxide; Activation, Metabolic; Animal Testing Alternatives; Anthracenes; Benzo(a)pyrene; Comet Assay; DNA Damage; Gene Expression Regulation, Enzymologic; Hep G2 Cells; Hepatocytes; Histones; Humans; Imidazoles; Liver; Phosphorylation; Spheroids, Cellular; Time Factors | 2021 |