2-amino-1-8-naphthyridine and titanium-isopropoxide

2-amino-1-8-naphthyridine has been researched along with titanium-isopropoxide* in 1 studies

Other Studies

1 other study(ies) available for 2-amino-1-8-naphthyridine and titanium-isopropoxide

Article	Year
Design and Synthesis of Cyclic Mismatch-Binding Ligands (CMBLs) with Variable Linkers by Ring-Closing Metathesis and their Photophysical and DNA Repeat Binding Properties. Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Aug-22, Volume: 23, Issue:47 Cyclophane-containing bis(2-amino-1,8-naphthyridine) moieties attached to variable linkers at the C2-position (linker B) were synthesized as cyclic mismatch-binding ligands (CMBLs). Ring-closing metathesis (RCM) is used as a key step for the introduction of double bonds at the linker B. Decreasing the size of the linker of the substrate, formation of the RCM products with an increasing trans/cis (E/Z) ratio was observed with moderate to high overall yields. Concentration-dependent fluorescence spectra were observed for CMBLs with longer linkers (n=3), whereas concentration-independent spectra were observed for CMBLs with shorter linkers (n=2 and/or 1) with a marked exception of the E-alkene 6 a. Concomitant changes in the absorption as well as in the fluorescence spectra were also observed for the CMBLs with an increasing hydrophobicity of the solvent. Absorption and fluorescence spectra of the CMBLs in solutions containing 99-100 % methanol resembled to that of the monomer. The binding behavior of these CMBLs with repeat DNA structures was investigated by using a surface plasmon resonance (SPR) assay and circular dichroism (CD) spectra. The cyclic E-alkenes 1 a (n=3) and 3 a (n=2) show an orthogonal binding relationship with d(CCTG) Topics: Alkenes; Catalysis; Circular Dichroism; DNA; Heterocyclic Compounds; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Naphthyridines; Organometallic Compounds; Solvents; Spectrometry, Fluorescence; Stereoisomerism; Structure-Activity Relationship; Surface Plasmon Resonance	2017

Article

Year

Design and Synthesis of Cyclic Mismatch-Binding Ligands (CMBLs) with Variable Linkers by Ring-Closing Metathesis and their Photophysical and DNA Repeat Binding Properties.

Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Aug-22, Volume: 23, Issue:47

Cyclophane-containing bis(2-amino-1,8-naphthyridine) moieties attached to variable linkers at the C2-position (linker B) were synthesized as cyclic mismatch-binding ligands (CMBLs). Ring-closing metathesis (RCM) is used as a key step for the introduction of double bonds at the linker B. Decreasing the size of the linker of the substrate, formation of the RCM products with an increasing trans/cis (E/Z) ratio was observed with moderate to high overall yields. Concentration-dependent fluorescence spectra were observed for CMBLs with longer linkers (n=3), whereas concentration-independent spectra were observed for CMBLs with shorter linkers (n=2 and/or 1) with a marked exception of the E-alkene 6 a. Concomitant changes in the absorption as well as in the fluorescence spectra were also observed for the CMBLs with an increasing hydrophobicity of the solvent. Absorption and fluorescence spectra of the CMBLs in solutions containing 99-100 % methanol resembled to that of the monomer. The binding behavior of these CMBLs with repeat DNA structures was investigated by using a surface plasmon resonance (SPR) assay and circular dichroism (CD) spectra. The cyclic E-alkenes 1 a (n=3) and 3 a (n=2) show an orthogonal binding relationship with d(CCTG)

Topics: Alkenes; Catalysis; Circular Dichroism; DNA; Heterocyclic Compounds; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Naphthyridines; Organometallic Compounds; Solvents; Spectrometry, Fluorescence; Stereoisomerism; Structure-Activity Relationship; Surface Plasmon Resonance

2017