2-amino-1,3,4-thiadiazole has been researched along with tiazofurin in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, T; Hatakeyama, K; Kagamiyama, H | 1 |
| Leyland-Jones, B; O'Dwyer, PJ; Stewart, JA; Wagner, BH | 1 |
1 review(s) available for 2-amino-1,3,4-thiadiazole and tiazofurin
| Article | Year |
|---|---|
Aminothiadiazole: an antineoplastic thiadiazole.
Topics: Allopurinol; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Humans; IMP Dehydrogenase; Mice; Neoplasms, Experimental; Purines; Rats; Ribavirin; Thiadiazoles | 1986 |
1 trial(s) available for 2-amino-1,3,4-thiadiazole and tiazofurin
| Article | Year |
|---|---|
Aminothiadiazole: an antineoplastic thiadiazole.
Topics: Allopurinol; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Humans; IMP Dehydrogenase; Mice; Neoplasms, Experimental; Purines; Rats; Ribavirin; Thiadiazoles | 1986 |
1 other study(ies) available for 2-amino-1,3,4-thiadiazole and tiazofurin
| Article | Year |
|---|---|
IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels. Indications of the regulation of GTP cyclohydrolase I activity by restriction of GTP availability in the cells.
Topics: Animals; Antineoplastic Agents; Biopterins; GTP Cyclohydrolase; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Kinetics; Mycophenolic Acid; Neuroblastoma; PC12 Cells; Ribavirin; Thiadiazoles; Tumor Cells, Cultured | 1992 |