Compounds > 2-acetylaminofluorene
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2-acetylaminofluorene and phenacetin

2-acetylaminofluorene has been researched along with phenacetin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Frankel, HH; Weisburger, EK; Yamamoto, RS1
Glowinski, IB; King, CM; Vaught, JB1
Hanna, PE; Smith, TJ1
Kitamura, S; Tatsumi, K1
Glowinski, IB; Hayashi, S; Sanderson, ND; Thorgeirsson, SS1
Bartsch, H1
Alewood, P; Calder, I; Thorgeirsson, SS; Wirth, PJ1
Gillette, JR; Hinson, JA; Pohl, LR1
Kitamura, S; Ohta, S; Sugihara, K; Tatsumi, K1

Reviews

1 review(s) available for 2-acetylaminofluorene and phenacetin

ArticleYear
Metabolic activation of aromatic amines and azo dyes.
    IARC scientific publications, 1981, Issue:40

    Topics: 1-Naphthylamine; 2-Acetylaminofluorene; 2-Naphthylamine; 4-Nitroquinoline-1-oxide; Amines; Aminobiphenyl Compounds; Animals; Azo Compounds; Biotransformation; Carcinogens; Coloring Agents; Heterocyclic Compounds; Humans; Nitrofurans; p-Aminoazobenzene; Phenacetin

1981

Other Studies

9 other study(ies) available for 2-acetylaminofluorene and phenacetin

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Effect of phenacetin and N-alkylacetanilides on N-2-fluorenylacetamide hepatocarcinogenesis.
    Cancer letters, 1979, Volume: 8, Issue:2

    Topics: 2-Acetylaminofluorene; Acetanilides; Animals; Liver Neoplasms; Male; Neoplasms, Experimental; Phenacetin; Rats

1979
Metabolism of N-hydroxy-2-acetylaminofluorene and N-hydroxy-phenacetin by guinea pig liver microsomal enzymes.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: 2-Acetylaminofluorene; Acetyl-CoA Hydrolase; Animals; Binding, Competitive; Chromatography, Gel; Chromatography, High Pressure Liquid; Colorimetry; Female; Guinea Pigs; Hydroxyacetylaminofluorene; In Vitro Techniques; Microsomes, Liver; Phenacetin; RNA, Transfer; Thiolester Hydrolases

1985
N-acetyltransferase multiplicity and the bioactivation of N-arylhydroxamic acids by hamster hepatic and intestinal enzymes.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: 2-Acetylaminofluorene; 4-Aminobenzoic Acid; Acetylation; Acetyltransferases; Acyltransferases; Aminobenzoates; Animals; Biotransformation; Carcinogens; Chromatography, Affinity; Cricetinae; Hydroxyacetylaminofluorene; Intestines; Liver; Male; Mesocricetus; p-Aminoazobenzene; Phenacetin; RNA, Transfer

1986
N-hydroxy-2-acetylaminofluorene as effective inhibitor of aldehyde oxidase.
    Biochemical and biophysical research communications, 1986, Jul-16, Volume: 138, Issue:1

    Topics: 2-Acetylaminofluorene; Aldehyde Oxidase; Aldehyde Oxidoreductases; Aminobiphenyl Compounds; Animals; Cysteine; Dithiothreitol; Fluorenes; Glutathione; Hydroxamic Acids; Hydroxyacetylaminofluorene; Kinetics; Male; Phenacetin; Rabbits; Serum Albumin, Bovine

1986
Metabolic activation and genotoxicity of N-hydroxy-2-acetylaminofluorene and N-hydroxyphenacetin derivatives in Reuber (H4-II-E) hepatoma cells.
    Cancer research, 1984, Volume: 44, Issue:3

    Topics: 2-Acetylaminofluorene; Acyltransferases; Animals; Biotransformation; Cell Line; DNA Replication; Dose-Response Relationship, Drug; Guinea Pigs; Hydroxyacetylaminofluorene; Kinetics; Liver Neoplasms, Experimental; Microsomes, Liver; Phenacetin; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1984
Mutagenicity of N-hydroxy-2-acetylaminofluorene and N-hydroxy-phenacetin and their respective deacetylated metabolites in nitroreductase deficient Salmonella TA98FR and TA100FR.
    Carcinogenesis, 1982, Volume: 3, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Ascorbic Acid; Cricetinae; Hydroxyacetylaminofluorene; Male; Mesocricetus; Microsomes, Liver; Mutagenicity Tests; Mutation; Nitro Compounds; Nitroreductases; Oxidoreductases; Phenacetin; Rats; Rats, Inbred Strains; Salmonella

1982
A simple high-pressure liquid chromatographic assay for the N-hydroxy derivatives of phenacetin, acetaminophen, 2-acetylaminofluorene, and other hydroxamic acids.
    Analytical biochemistry, 1980, Jan-15, Volume: 101, Issue:2

    Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cricetinae; Hydroxamic Acids; Hydroxyacetylaminofluorene; Male; Mesocricetus; Microsomes, Liver; Phenacetin; Spectrophotometry; Structure-Activity Relationship

1980
Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood.
    Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Blood; Carbon Monoxide; Catalase; Erythrocytes; Flavin-Adenine Dinucleotide; Hemoglobins; Hydroxamic Acids; Kinetics; Male; Models, Biological; NADP; Niacinamide; Oxygen; Phenacetin; Rabbits; Rats; Salicylamides; Time Factors

2000