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2-acetylaminofluorene and n-(deoxyguanosin-8-yl)-2-aminofluorene

2-acetylaminofluorene has been researched along with n-(deoxyguanosin-8-yl)-2-aminofluorene in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19907 (29.17)18.7374
1990's12 (50.00)18.2507
2000's3 (12.50)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beland, FA; Meerman, JH; Mulder, GJ; Timmers-Reker, AJ; Wedzinga, R; Wierckx, FC1
Gentles, R; Grollman, AP; Johnson, F; Shibutani, S1
Annan, RS; Giese, RW; Vouros, P1
Beland, FA; Fullerton, NF; Marques, MM; Melchior, WB; Poirier, MC; Smith, BA1
Retèl, J; van Grondelle, R; van Houte, LP; Westra, JG1
Baron, J; Huitfeldt, HS; Poirier, MC; Spangler, EF1
Gupta, PK; Johnson, DL; King, CM; Lee, MS; Reid, TM; Romano, LJ1
Huitfeldt, HS; Hunt, JM; Pitot, HC; Poirier, MC1
Arce, GT; Cline, DT; Mead, JE1
Evans, FE; Levine, RA1
Metzger, G; Ross, J; Werbin, H1
Kriek, E; Westra, JG1
Doisy, R; Tang, MS1
Giese, RW; Vouros, P1
Beland, FA; Culp, SJ; Poirier, MC1
Coin, F; Fuchs, RP; Koffel-Schwartz, N; Veaute, X1
Downey, KM; Fisher, PA; Mozzherin, DJ; Shibutani, S; Tan, CK1
Grollman, AP; Shibutani, S; Suzuki, N1
Cho, BP; Zhou, L1
Grollman, AP; Hayashi, K; Ohashi, E; Ohmori, H; Shibutani, S; Suzuki, N1
Grollman, AP; Shibutani, S; Suzuki, N; Tan, X1
Alzeer, J; Gillet, LC; Schärer, OD1
Broyde, S; Geacintov, NE; Kolbanovskiy, A; Kolbanovskiy, M; Kropachev, K; Mu, H; Wang, L; Zhang, L1
Markiewicz, RP; Romano, LJ; Rueda, D; Vrtis, KB1

Other Studies

24 other study(ies) available for 2-acetylaminofluorene and n-(deoxyguanosin-8-yl)-2-aminofluorene

ArticleYear
DNA adduct formation in liver following the administration of [3H]2-nitrofluorene to rats in vivo.
    Carcinogenesis, 1991, Volume: 12, Issue:11

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Epoxide Hydrolases; Epoxy Compounds; Fluorenes; Injections, Intravenous; Liver; Male; Masoprocol; Rats; Rats, Inbred Strains; RNA; Trichloroepoxypropane; Trifluoroacetic Acid

1991
Isolation and characterization of oligodeoxynucleotides containing dG-N2-AAF and oxidation products of dG-C8-AF.
    Carcinogenesis, 1991, Volume: 12, Issue:5

    Topics: 2-Acetylaminofluorene; Chromatography, High Pressure Liquid; Deoxyguanosine; Electrophoresis, Polyacrylamide Gel; Fluorenes; Hydrogen-Ion Concentration; Mutagens; Oxidation-Reduction; Spectrophotometry, Ultraviolet

1991
Detection and structural characterization of amino polyaromatic hydrocarbon-deoxynucleoside adducts using fast atom bombardment and tandem mass spectrometry.
    Analytical biochemistry, 1990, Nov-15, Volume: 191, Issue:1

    Topics: 2-Acetylaminofluorene; Deoxyguanosine; DNA; Fluorenes; Molecular Structure; Phenanthrenes; Spectrometry, Mass, Fast Atom Bombardment

1990
DNA adduct formation in relation to tumorigenesis in mice continuously administered 4-aminobiphenyl.
    Progress in clinical and biological research, 1990, Volume: 340A

    Topics: 2-Acetylaminofluorene; Aminobiphenyl Compounds; Animals; Carcinogens; Deoxyguanosine; DNA; DNA Damage; DNA Mutational Analysis; DNA, Neoplasm; DNA, Recombinant; Escherichia coli; Female; Fluorenes; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Organ Specificity; Sex Factors; Urinary Bladder Neoplasms

1990
The fluorescence emission properties of dGuo-C8-AAF, dGuo-C8-AF and the imidazole ring-opened products of dGuo-C8-AF indicate a different dynamic structure for the various compounds.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: 2-Acetylaminofluorene; Circular Dichroism; Deoxyguanosine; Fluorenes; Fluorescence; Imidazoles; Molecular Structure

1990
Microfluorometric determination of DNA adducts in immunofluorescent-stained liver tissue from rats fed 2-acetylaminofluorene.
    Cancer research, 1987, Apr-15, Volume: 47, Issue:8

    Topics: 2-Acetylaminofluorene; Animals; Bile Ducts; Deoxyguanosine; Epithelium; Fluorenes; Fluorescent Antibody Technique; Fluorometry; Liver; Male; Radioimmunoassay; Rats; Rats, Inbred F344; Staining and Labeling

1987
Mutagenesis by single site-specific arylamine-DNA adducts. Induction of mutations at multiple sites.
    The Journal of biological chemistry, 1989, Nov-25, Volume: 264, Issue:33

    Topics: 2-Acetylaminofluorene; Base Sequence; Coliphages; Deoxyguanosine; DNA, Viral; Escherichia coli; Fluorenes; Molecular Sequence Data; Mutagens; Mutation; Phenotype; Restriction Mapping; SOS Response, Genetics; Transfection

1989
Lack of acetylaminofluorene--DNA adduct formation in enzyme-altered foci of rat liver.
    Carcinogenesis, 1988, Volume: 9, Issue:4

    Topics: 2-Acetylaminofluorene; Adenosine Triphosphatases; Animals; Carcinogens; Deoxyguanosine; Fluorenes; Fluorescent Antibody Technique; gamma-Glutamyltransferase; Glucose-6-Phosphatase; Histocytochemistry; Liver; Male; Rats; Rats, Inbred F344

1988
The 32P-post-labeling method in quantitative DNA adduct dosimetry of 2-acetylaminofluorene-induced mutagenicity in Chinese hamster ovary cells and Salmonella typhimurium TA1538.
    Carcinogenesis, 1987, Volume: 8, Issue:4

    Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cells, Cultured; Cricetinae; Deoxyguanosine; DNA; Dose-Response Relationship, Drug; Fluorenes; Mutagenicity Tests; Phosphorus Radioisotopes; Salmonella typhimurium

1987
Conformational analysis of the 2'-deoxyribofuranose ring from proton-proton coupling constants: analysis of a nucleoside-carcinogen adduct formed from 2-acetylaminofluorene utilizing a three-state model.
    Biopolymers, 1987, Volume: 26, Issue:7

    Topics: 2-Acetylaminofluorene; Computer Simulation; Deoxyguanosine; Deoxyribose; Fluorenes; Models, Genetic; Models, Molecular; Molecular Conformation

1987
Conformation of 2-[(deoxyguanosin-8-ylacetyl)amino]fluorene differs in protein-free deoxyribonucleic acid and chromatin.
    Biochemistry, 1982, Mar-16, Volume: 21, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Cattle; Chromatin; Deoxyguanosine; DNA; Endonucleases; Fluorenes; In Vitro Techniques; Liver; Molecular Conformation; Nucleic Acid Conformation; Nucleosomes; Rats; Rats, Inbred Strains; Thymus Gland

1982
Structural identification of the pyrimidine derivatives formed from N-(deoxyguanosin-8-yl)-2-aminofluorene in aqueous solution at alkaline pH.
    Carcinogenesis, 1980, Volume: 1, Issue:6

    Topics: 2-Acetylaminofluorene; Chemical Phenomena; Chemistry; Deoxyguanosine; DNA; Fluorenes; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pyrimidines

1980
Effect of aminofluorene and (acetylamino)fluorene adducts on the DNA replication mediated by Escherichia coli polymerases I (Klenow fragment) and III.
    Biochemistry, 1995, Apr-04, Volume: 34, Issue:13

    Topics: 2-Acetylaminofluorene; Base Sequence; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; DNA Polymerase I; DNA Polymerase III; DNA Replication; DNA, Single-Stranded; Escherichia coli; Fluorenes; Molecular Sequence Data

1995
Methods development toward the measurement of polyaromatic hydrocarbon-DNA adducts by mass spectrometry.
    Research report (Health Effects Institute), 1993, Issue:61

    Topics: 2-Acetylaminofluorene; Animals; Benzene; Benzo(a)pyrene; Carcinogens, Environmental; Chromatography, Gas; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Electrophoresis; Fluorenes; Humans; Hydrazines; Hydrogenation; Mass Spectrometry; Oxidation-Reduction; Polycyclic Compounds; Pyrenes; Spectrometry, Mass, Fast Atom Bombardment; Superoxides

1993
Biphasic removal of DNA adducts in a repetitive DNA sequence after dietary administration of 2-acetylaminofluorene.
    Environmental health perspectives, 1993, Volume: 99

    Topics: 2-Acetylaminofluorene; Animals; Biomarkers; Deoxyguanosine; Diet; DNA; DNA Damage; DNA Repair; Fluorenes; Kinetics; Liver; Male; Rats; Rats, Inbred F344; Repetitive Sequences, Nucleic Acid

1993
Cellular strategies for accommodating replication-hindering adducts in DNA: control by the SOS response in Escherichia coli.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-23, Volume: 93, Issue:15

    Topics: 2-Acetylaminofluorene; Base Sequence; Carcinogens; Deoxyguanosine; DNA Adducts; DNA Damage; DNA Replication; Escherichia coli; Fluorenes; Guanine; Molecular Sequence Data; Mutagenesis; Oligonucleotide Probes; Restriction Mapping; SOS Response, Genetics; Ultraviolet Rays

1996
Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Jun-10, Volume: 94, Issue:12

    Topics: 2-Acetylaminofluorene; 8-Hydroxy-2'-Deoxyguanosine; Animals; Base Sequence; Binding Sites; Cattle; Deoxyguanosine; DNA Damage; DNA Polymerase III; DNA Primers; DNA Replication; DNA-Directed DNA Polymerase; Fluorenes; Humans; Mammals; Mutagenesis; Proliferating Cell Nuclear Antigen; Recombinant Proteins; Templates, Genetic; Thymus Gland

1997
Mutagenic specificity of (acetylamino)fluorene-derived DNA adducts in mammalian cells.
    Biochemistry, 1998, Sep-01, Volume: 37, Issue:35

    Topics: 2-Acetylaminofluorene; Animals; Catalysis; COS Cells; Deoxyguanosine; DNA Adducts; DNA Polymerase I; DNA Primers; Fluorenes; Genetic Vectors; Mutagenesis, Insertional; Mutagens; Sequence Deletion; Transfection

1998
Probing the conformational heterogeneity of the acetylaminofluorene-modified 2'-deoxyguanosine and DNA by 19F NMR spectroscopy.
    Biochemistry, 1999, Jun-08, Volume: 38, Issue:23

    Topics: 2-Acetylaminofluorene; Carcinogens; Deoxyguanosine; DNA Adducts; DNA, Single-Stranded; Fluorenes; Fluorine; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Solvents; Thermodynamics

1999
Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV.
    Biochemistry, 2001, Dec-18, Volume: 40, Issue:50

    Topics: 2-Acetylaminofluorene; Animals; Base Sequence; COS Cells; Deoxyguanosine; DNA Adducts; DNA Polymerase beta; DNA-Directed DNA Polymerase; Escherichia coli; Fluorenes; Humans; In Vitro Techniques; Kinetics; Mutagenesis, Site-Directed; Proteins; Recombinant Proteins; Sequence Deletion

2001
Mutagenic events in Escherichia coli and mammalian cells generated in response to acetylaminofluorene-derived DNA adducts positioned in the Nar I restriction enzyme site.
    Biochemistry, 2002, Dec-03, Volume: 41, Issue:48

    Topics: 2-Acetylaminofluorene; Animals; Chlorocebus aethiops; COS Cells; Deoxyguanosine; Deoxyribonucleases, Type II Site-Specific; DNA Adducts; DNA Mutational Analysis; DNA, Single-Stranded; Escherichia coli; Fluorenes; Frameshift Mutation; Mutagens; Oligodeoxyribonucleotides; Plasmids; Point Mutation

2002
Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis.
    Nucleic acids research, 2005, Volume: 33, Issue:6

    Topics: 2-Acetylaminofluorene; Biochemistry; Deoxyguanosine; DNA Adducts; DNA Repair; Fluorenes; HeLa Cells; Humans; Oligodeoxyribonucleotides

2005
Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies.
    Nucleic acids research, 2012, Volume: 40, Issue:19

    Topics: 2-Acetylaminofluorene; Base Sequence; Deoxyguanosine; DNA Adducts; DNA Repair; Fluorenes; HeLa Cells; Humans; Molecular Dynamics Simulation; Nucleic Acid Conformation

2012
Carcinogenic adducts induce distinct DNA polymerase binding orientations.
    Nucleic acids research, 2013, Volume: 41, Issue:16

    Topics: 2-Acetylaminofluorene; Carcinogens; Deoxyguanosine; DNA; DNA Adducts; DNA Polymerase I; Fluorenes; Fluorometry; Protein Binding

2013