2-acetylaminofluorene has been researched along with benzo(a)pyrene in 81 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (50.62) | 18.7374 |
| 1990's | 29 (35.80) | 18.2507 |
| 2000's | 10 (12.35) | 29.6817 |
| 2010's | 1 (1.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belitsky, GA; Khitrovo, IA; Khovanova, EM; Lytcheva, TA; Safaev, RD; Spiegelman, VS; Ugnivenko, HG | 1 |
| Butterworth, BE; Eldridge, SR; Gould, MN | 1 |
| Gupta, RC; Monteith, DK | 1 |
| Aidoo, A; Gao, N; Heflich, RH | 1 |
| Reddy, MV | 2 |
| Allison, JC; Claxton, LD; Creason, J; Houk, VS | 1 |
| Eriksson, LC; Ritter, E | 1 |
| Majeska, JB; Matheson, DW | 1 |
| Cassand, P; Decoudu, S; Leveque, F; Narbonne, JF | 1 |
| Michalopoulos, G; Monteith, DK; Strom, SC | 1 |
| Burgess, WM; Huggett, A; McManus, ME; Quattrochi, LC; Tukey, RH; Veronese, ME | 1 |
| Hasegawa, R; Imaida, K; Ito, N; Mutai, M; Tsuda, H; Yamaguchi, S | 1 |
| Juchau, MR; Namkung, MJ; Yang, HY | 1 |
| Beales, S; Suter, W | 1 |
| Cameron, RG | 1 |
| Randerath, K; Schurdak, ME | 1 |
| Goldin, BR; Hackford, AW; Mayhew, JW | 1 |
| Hsia, MT; Kreamer, BL; Pitot, HC; Sattler, GL; Sawada, N; Staecker, JL | 1 |
| Ernst, MK; Hillesund, T; Poiley, JA; Raineri, R; Tennant, RW | 1 |
| Dauterman, WC; Langenbach, R; Rudo, KM | 1 |
| Doolittle, DJ; Lee, DA; Rahn, CA | 1 |
| Anderson, TM; Cameron, JW; Hatch, GG; Kouri, RE; Lubet, RA; Nims, RW; Putman, DL; Schechtman, LM; Spalding, JW; Tennant, RW | 1 |
| Baklanova-Elkina, EIu; Bulyzhenkov, VE; Ivanov, VI; Kaurov, BA; Vikulova, VK | 1 |
| Bakke, JP; Green, CE; Mirsalis, JC; Spak, DK; Steinmetz, KL | 1 |
| McQueen, CA; Way, BM; Williams, GM | 1 |
| Hulla, JE; Juchau, MR; Namkung, MJ; Yang, HL | 1 |
| Lee, MS; Nath, ST; Romano, LJ | 1 |
| Birt, DF; Bresnick, E; Tibbels, MG; Walker, B | 1 |
| Geeroms, D; Mainguet, P; Roberfroid, M; Wilpart, M | 1 |
| Fukui, S; Hirai, K; Hirayama, T; Nohara, M; Ogawa, S; Tokuda, M | 1 |
| Green, NR; Ponder, DL | 1 |
| Boyle, JM; Strickland, PT | 1 |
| Miyauchi, M | 1 |
| Bliznakov, EG; Guttenplan, JB | 1 |
| Kligerman, AD; Michalopoulos, G; Strom, S | 1 |
| Ioannides, C; Parke, DV; Parkinson, C | 1 |
| Hicks, RM; Knowles, MA; Moore, BP; Redgrave, S | 1 |
| Malejka-Giganti, D; Ritter, CL | 1 |
| Razzouk, C; Roberfroid, MB | 1 |
| Hagiwara, A; Hasegawa, R; Ito, N; Shirai, T; Tatematsu, M; Tsuda, H | 1 |
| Cayama, E; Enomoto, K; Farber, E; Lee, G; Solt, DB; Tsuda, H | 1 |
| Aström, A; DePierre, JW; Meijer, J | 1 |
| Kreiser, DM; McQueen, CA; Williams, GM | 1 |
| Nomura, S; Oishi, M; Shobu, N | 1 |
| Farber, E; Ghoshal, AK | 1 |
| Decker, RW; Malejka-Giganti, D; Ritter, CL | 1 |
| Ali, B; Kaur, S | 1 |
| Harnasch, D; Stumpf, R | 1 |
| Dumas, L; Harvey, G; Pagé, M | 1 |
| Bagnasco, M; Bennicelli, C; Bojnemirski, A; Camoirano, A; De Flora, S; Kurelec, B | 1 |
| al-Maskati, HA; Dairi, MG; el-Din, AY; Mohamed, AY | 1 |
| Aoki, K; Kuroiwa, Y; Lee, H; Sakagami, H; Yoshida, T | 1 |
| Fort, FL; Fujikawa, K; Sakamoto, Y; Samejima, K | 1 |
| Garriott, ML; Huffman, DM; Oberly, TJ; Scheuring, JC | 1 |
| Grollman, AP; Shibutani, S | 1 |
| Konopacka, M | 1 |
| Ioannides, C; Lewis, DF; Parke, DV | 1 |
| Hewer, A; Phillips, DH | 1 |
| Castegnaro, M; Phillips, DH | 1 |
| Giese, RW; Vouros, P | 1 |
| Burchell, B; Jin, CJ; Mackenzie, PI; Miners, JO | 1 |
| Iyanagi, T; Mackenzie, PI; Rodbourn, L | 1 |
| Balansky, R; D'Agostini, F; De Flora, S; Izzotti, A; Scatolini, L | 1 |
| Galloway, SM; Johnson, TE; Umbenhauer, DR | 1 |
| Harvey, JS; Parry, JM | 1 |
| Bol, SA; de Groot, AJ; de Vries, A; Jansen, JG; Mullenders, LH; Tates, AD; Van Oostrom, C; van Steeg, H; van Zeeland, AA; Vrieling, H | 1 |
| Mullenders, LH; van Steeg, H; Vijg, J | 1 |
| Cano, JP; Sabatier, R; Vian, L; Yusuf, AT | 1 |
| Geacintov, NE; Rechkoblit, O; Taylor, JS; Wang, M; Wang, Z; Wu, X; Yuan, F; Zhang, Y | 1 |
| Fuchs, RP; Janel-Bintz, R; Napolitano, R; Wagner, J | 1 |
| Iype, PT; Kelley, S; Ray-Chaudhuri, R | 1 |
| Daniel, MR; Dehnel, JM | 1 |
| Ajith, TA; Joseph, S; Kuttan, R; Raphael, KR | 1 |
| Inami, K; Mochizuki, M | 1 |
| Cano, JP; Guyomard, C; Vian, L; Yusuf, A | 1 |
| Chagnon, MC; Le Bon, AM; Le Hegarat, L; Lhuguenot, JC; Valentin-Severin, I | 1 |
| HEIDELBERGER, C; RIEKE, HS | 1 |
| Ahr, HJ; Duan, JD; Enzmann, HH; Jeffrey, AM; Perrone, CE; Schmidt, U; Williams, GM | 1 |
| Verdina, A | 1 |
| Borlak, J; Corvi, R; Linge, J; Maaser, K; Rohrbeck, A; Salinas, G; Salovaara, S | 1 |
3 review(s) available for 2-acetylaminofluorene and benzo(a)pyrene
| Article | Year |
|---|---|
Immunoassay of carcinogen-modified DNA.
Topics: 2-Acetylaminofluorene; Aflatoxins; Alkylation; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Base Sequence; Benzo(a)pyrene; Carcinogens; Cisplatin; DNA; Haptens; Immunization Schedule; Immunologic Techniques; Nucleic Acid Conformation; Nucleosides; Nucleotides; Polynucleotides; Radiation, Ionizing; RNA; Ultraviolet Rays | 1984 |
Mutagenic specificity of chemical carcinogens as determined by studies of single DNA adducts.
Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Benzo(a)pyrene; Carcinogens; DNA; DNA Adducts; Humans; Molecular Sequence Data; Mutagenesis; Sensitivity and Specificity | 1994 |
Carcinogen-modified DNA and specific humoral immunity toward carcinogen-DNA adducts. A review.
Topics: 2-Acetylaminofluorene; Animals; Antibody Formation; Benzo(a)pyrene; Carcinogens; DNA Adducts; Male; Mice | 2006 |
78 other study(ies) available for 2-acetylaminofluorene and benzo(a)pyrene
| Article | Year |
|---|---|
A Drosophila simulans mutant strain sensitive to benzo[a]pyrene and 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Drosophila; Drosophila melanogaster; Environmental Monitoring; Female; Heterozygote; Male; Mutagenicity Tests; Mutagens; Polychlorinated Biphenyls; Salmonella typhimurium | 1992 |
Genotoxicity of environmental agents in human mammary epithelial cells.
Topics: 2-Acetylaminofluorene; Adult; Aflatoxin B1; Benzo(a)pyrene; Breast; DNA Repair; DNA, Neoplasm; Environmental Pollutants; Epithelial Cells; Epithelium; Female; Humans; Mutagenicity Tests; Pyrenes | 1992 |
Carcinogen-DNA adducts in cultures of rat and human hepatocytes.
Topics: 2-Acetylaminofluorene; Aminobiphenyl Compounds; Benzo(a)pyrene; Carcinogens; Cells, Cultured; DNA; DNA Damage; In Vitro Techniques; Liver | 1992 |
Analysis of rat lymphocyte activation of benzo[a]pyrene, 2-acetylaminofluorene, and several of their metabolites to mutagenic and DNA-damaging species in vitro.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Biotransformation; Cells, Cultured; CHO Cells; Cricetinae; DNA Damage; DNA, Superhelical; Lymphocytes; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred F344; Salmonella typhimurium | 1991 |
Nuclease S1-mediated enhancement of the 32P-postlabeling assay for aromatic carcinogen-DNA adducts.
Topics: 2-Acetylaminofluorene; Autoradiography; Benzo(a)pyrene; Benzoquinones; Carcinogens; Chromatography, Thin Layer; DNA; DNA Damage; Phosphorus Radioisotopes; Single-Strand Specific DNA and RNA Endonucleases | 1991 |
Evaluating the relationship of metabolic activation system concentrations and chemical dose concentrations for the Salmonella spiral and plate assays.
Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Benzo(a)pyrene; Biotransformation; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Factor Analysis, Statistical; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1991 |
Kinetics of induction of cytosolic benzaldehyde: NADP and propionaldehyde: NAD aldehyde dehydrogenase activities in rat livers from male Wistar rats.
Topics: 2-Acetylaminofluorene; Aldehyde Dehydrogenase; Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Enzyme Induction; Glutathione Transferase; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Inbred Strains | 1991 |
Development of an optimal S9 activation mixture for the L5178Y TK+/- mouse lymphoma mutation assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Cyclophosphamide; Dimethylnitrosamine; Lymphoma; Methylcholanthrene; Mice; Microsomes, Liver; Mutagenicity Tests; NADP; Thymidine Kinase; Time Factors; Tumor Cells, Cultured | 1990 |
Relationship between vitamin A dietary intake and mutagenic activity of some chemical carcinogens.
Topics: 2-Acetylaminofluorene; Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Dose-Response Relationship, Drug; Drug Interactions; Liver; Male; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium; Vitamin A | 1990 |
Conjugation of chemical carcinogens by primary cultures of human hepatocytes.
Topics: 2-Acetylaminofluorene; Benzo(a)pyrene; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Glucuronates; Humans; Hydroxylation; Inactivation, Metabolic; Liver; Sulfates | 1990 |
Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
Topics: 2-Acetylaminofluorene; Adolescent; Adult; Aged; Benzo(a)pyrene; Cell Line; Child; Cytochrome P-450 Enzyme System; Food Contamination; Gene Expression; Humans; Hydroxylation; Imidazoles; Microsomes, Liver; Middle Aged; Quinolines; Quinoxalines | 1990 |
Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Diethylnitrosamine; Drug Synergism; Glutathione Transferase; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred F344; Thioacetamide | 1989 |
Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis.
Topics: 2-Acetylaminofluorene; Amnion; Animals; Benzo(a)pyrene; Benzoflavones; Chorion; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Enzyme Induction; Female; Gestational Age; Immunologic Techniques; Isoenzymes; Methylcholanthrene; Metyrapone; Morphogenesis; Oxazines; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Yolk Sac | 1989 |
DNA repair induction by UV irradiation and various mutagens requiring metabolic activation in rat hepatocytes maintained in culture for several days.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Biotransformation; Cells, Cultured; Cytochrome P-450 Enzyme System; DNA Repair; Dose-Response Relationship, Radiation; Enzyme Stability; Hydrogen Peroxide; Liver; Male; Mutagens; Rats; Rats, Inbred Strains; Ultraviolet Rays | 1989 |
Identification of the putative first cellular step of chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Biomarkers, Tumor; Bromodeoxyuridine; Cell Division; Diethylnitrosamine; Dose-Response Relationship, Drug; Drug Resistance; Glutathione Transferase; Hepatectomy; Immunoenzyme Techniques; Liver Neoplasms, Experimental; Liver Regeneration; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1989 |
Effects of route of administration on tissue distribution of DNA adducts in mice: comparison of 7H-dibenzo(c,g)carbazole, benzo(a)pyrene, and 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Administration, Oral; Administration, Topical; Animals; Benzo(a)pyrene; Biotransformation; Carbazoles; DNA; Injections, Subcutaneous; Male; Mice; Mice, Inbred BALB C; Tissue Distribution | 1989 |
An isolated perfused model for the study of colonic metabolism and transport.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Biological Transport; Cholecalciferol; Colon; Estradiol; In Vitro Techniques; Male; Models, Biological; Perfusion; Rats | 1988 |
Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Cell Membrane; Cell Separation; Cell Survival; Centrifugation, Density Gradient; Cytochrome P-450 Enzyme System; Dexamethasone; DNA; DNA Repair; Enzyme Induction; Glucagon; Liver; Male; Rats; Rats, Inbred Strains; Tyrosine Transaminase | 1986 |
Increased carcinogen metabolism and survival of retrovirus-infected Fischer rat embryo cells following repetitive carcinogen treatment.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Diethylnitrosamine; Embryo, Mammalian; Female; Kinetics; Pregnancy; Rats; Rats, Inbred F344 | 1985 |
Human and rat kidney cell metabolism of 2-acetylaminofluorene and benzo(a)pyrene.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Biotransformation; Humans; Kidney; Liver; Male; Mutagens; Rats; Rats, Inbred F344; Species Specificity | 1989 |
The use of rat urine extracted on XAD-2 resin and assayed in a microsuspension-modified Ames test as an in vivo indicator of genotoxic exposure.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Chromatography, Ion Exchange; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Urine | 1988 |
Analysis of the interlaboratory and intralaboratory reproducibility of the enhancement of simian adenovirus SA7 transformation of Syrian hamster embryo cells by model carcinogenic and noncarcinogenic compounds.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Adenoviruses, Simian; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chromates; Cocarcinogenesis; Cricetinae; Diethylnitrosamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Lead; Mesocricetus; Methylnitronitrosoguanidine | 1986 |
[The lack of ability of carcinogens and non-carcinogenic analogs to induce sex-linked recessive lethals in Drosophila melanogaster].
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Carcinogens; Drosophila melanogaster; Genes, Lethal; Genes, Recessive; Genetic Linkage; Mutagenicity Tests; Pyrenes; Structure-Activity Relationship; X Chromosome | 1987 |
Induction of unscheduled DNA synthesis in primary cultures of rat, mouse, hamster, monkey, and human hepatocytes.
Topics: 2-Acetylaminofluorene; Adult; Aflatoxin B1; Aflatoxins; Aminobiphenyl Compounds; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cricetinae; Dimethyl Sulfoxide; DNA; DNA Repair; Female; Haplorhini; Humans; Liver; Male; Mice; Rats; Species Specificity | 1988 |
Genotoxicity of carcinogens in human hepatocytes: application in hazard assessment.
Topics: 2-Acetylaminofluorene; Adult; Autoradiography; Benzo(a)pyrene; Carcinogens; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Female; Fluorenes; Humans; Liver; Male; Middle Aged | 1988 |
On the substrate specificity of cytochrome P450IIIA1.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Dealkylation; Dexamethasone; Enzyme Induction; Female; Hydroxylation; Isoenzymes; Pregnenolone; Rats; Rats, Inbred Strains; Substrate Specificity; Testosterone; Troleandomycin; Warfarin | 1988 |
Effect of carcinogenic adducts on transcription by T7 RNA polymerase.
Topics: 2-Acetylaminofluorene; Benzo(a)pyrene; Carcinogens; DNA Damage; DNA-Directed RNA Polymerases; Fluorenes; Genes, Synthetic; Substrate Specificity; T-Phages; Templates, Genetic; Transcription, Genetic; Viral Proteins | 1987 |
Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Chamomile; Female; Flavonoids; Indoles; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mice, Inbred Strains; Mutagens; Mutation; Neoplasms, Experimental; Oils, Volatile; Ornithine Decarboxylase; Plant Extracts; Plants, Medicinal; Skin; Tetradecanoylphorbol Acetate | 1986 |
Desmutagenic effects of N-acetylcysteine on direct and indirect mutagens.
Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Anthracenes; Azides; Benzo(a)pyrene; Biotransformation; Dose-Response Relationship, Drug; Fluorenes; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Sodium Azide | 1985 |
The effect of quercetin on the mutagenicity of 2-acetylaminofluorene and benzo[alpha]pyrene in Salmonella typhimurium strains.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Drug Synergism; Flavonoids; Mutation; Nitroquinolines; Quercetin; Salmonella typhimurium | 1985 |
Effects of dietary fats and butylated hydroxytoluene on mutagen activation in rats.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Butylated Hydroxytoluene; Dietary Fats; Drug Interactions; Fatty Acids; Fluorenes; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains | 1985 |
Conversion of procarcinogens to mutagens by the S-9 fraction from the liver of rainbow trout (Salmo gairdneri): inducibility with PCB, 3-methylcholanthrene and phenobarbital and inhibition by metyrapone and alpha-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Benzo(a)pyrene; Benzoflavones; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mutagenicity Tests; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonidae; Subcellular Fractions; Temperature; Trout | 1984 |
Activation of promutagens by liver homogenates isolated from female mice at different ages; lack of significant differences.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Dimethylnitrosamine; Female; Liver; Mice; Mutagenicity Tests; Mutagens; Salmonella typhimurium | 1981 |
Comparisons of the effects of chemical carcinogens in mixed cultures of rat hepatocytes and human fibroblasts.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Bromodeoxyuridine; Carcinogens; Cells, Cultured; Diethylnitrosamine; DNA; Fibroblasts; Humans; Liver; Male; Rats; Rats, Inbred Strains | 1981 |
Activation of benzo(a)pyrene and 2-acetamidofluorene to mutagens by microsomal preparations from different animal species: role of cytochrome P-450 and P-448.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Female; Guinea Pigs; Male; Mesocricetus; Methylcholanthrene; Mice; Microsomes, Liver; Mutagens; Phenobarbital; Rats; Rats, Inbred Strains | 1981 |
Metabolism and binding of benzo(a)pyrene and 2-acetylaminofluorene by short-term organ cultures of human and rat bladder.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Dihydroxydihydrobenzopyrenes; DNA; Epithelium; Female; Glucuronidase; Humans; Hydroxyacetylaminofluorene; Male; Organ Culture Techniques; Rats; Urinary Bladder | 1982 |
Mixed function oxidase in the mammary gland and liver microsomes of lactating rats. Effects of 3-methylcholanthrene and beta-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Female; Flavonoids; Lactation; Mammary Glands, Animal; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Species differences in the biochemical properties of liver microsomal arylamine and arylamide n-hydroxylases.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Cricetinae; Fluorenes; Isomerism; Male; Methylcholanthrene; Metyrapone; Mice; Miconazole; Microsomes, Liver; Mixed Function Oxygenases; Paraoxon; Rats; Species Specificity; Substrate Specificity | 1982 |
Induction of hyperplastic liver nodules in hepatectomized rats treated with 3'-methyl-4-dimethylaminoazobenzene, benzo[a]pyrene or phenobarbital before or after exposure to N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Carbon Tetrachloride; Hepatectomy; Hyperplasia; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred F344 | 1982 |
Promotion of liver cancer development by brief exposure to dietary 2-acetylaminofluorene plus partial hepatectomy or carbon tetrachloride.
Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Carbon Tetrachloride Poisoning; Cocarcinogenesis; Diet; Diethylnitrosamine; Dimethylhydrazines; Hepatectomy; Liver Neoplasms; Male; Methylnitrosourea; Rats; Rats, Inbred F344 | 1983 |
Characterization of the microsomal cytochrome P-450 species induced in rat liver by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Substrate Specificity | 1983 |
The hepatocyte primary culture/DNA repair assay using mouse or hamster hepatocytes.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cells, Cultured; Cricetinae; DNA Repair; Liver; Methyl Methanesulfonate; Mice; Nitrosamines; p-Dimethylaminoazobenzene | 1983 |
Tumor promoter 12-O-tetradecanoylphorbol 13-acetate stimulates simian virus 40 induction by DNA-damaging agents and tumor initiators.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Cells, Cultured; Cricetinae; Mesocricetus; Mitomycin; Mitomycins; Phorbols; Simian virus 40; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Virus Activation | 1983 |
The induction of resistant hepatocytes during initiation of liver carcinogenesis with chemicals in rats fed a choline deficient methionine low diet.
Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Choline Deficiency; Dimethylhydrazines; Hepatectomy; Liver Neoplasms, Experimental; Male; Methionine; Rats; Rats, Inbred F344 | 1983 |
Modifications of carcinogen metabolism in hepatic microsomes of suckling young by 3-methylcholanthrene or beta-naphthoflavone administered to lactating rats.
Topics: 2-Acetylaminofluorene; Animal Population Groups; Animals; Animals, Suckling; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Female; Flavonoids; Hydroxylation; Lactation; Methylcholanthrene; Microsomes, Liver; Pregnancy; Rats | 1983 |
The effects of phenobarbital, 3-methylcholanthrene and benzo(a)pyrene on the hydrolysis of xenobiotics in the rat.
Topics: 2-Acetylaminofluorene; Acetanilides; Amidohydrolases; Animals; Aspirin; Benzo(a)pyrene; Benzopyrenes; Carboxylic Ester Hydrolases; Female; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Procaine; Rats; Tissue Distribution | 1983 |
Studies on the induction of histocompatibility gene mutations in germ cells of mice by chemical mutagens and/or virus-inducing compounds.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Dimethyl Sulfoxide; Ethylnitrosourea; Major Histocompatibility Complex; Male; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Mutation; Nitrofurantoin; Statistics as Topic | 1984 |
Binding of environmental carcinogens to asbestos and mineral fibres.
Topics: 2-Acetylaminofluorene; Adsorption; Animals; Asbestos; Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Cell Line; Cell Survival; Cocarcinogenesis; Hemolysis; Hydrogen-Ion Concentration; Minerals; Nitrosamines; Sheep | 1984 |
Biotransformation of genotoxic agents in marine sponges. Mechanisms and modulation.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Carbolines; Glutathione; Glutathione Disulfide; Glutathione Transferase; Inactivation, Metabolic; Microsomes, Liver; Mutagens; Porifera; Quinolines; Rats; Salmonella typhimurium; Species Specificity; Vincristine | 1995 |
Acrylamide as an inducer of metabolic activation system (S9) in rats.
Topics: 2-Acetylaminofluorene; Acrylamide; Acrylamides; Aflatoxin B1; Animals; Azides; Benzo(a)pyrene; Biotransformation; Dose-Response Relationship, Drug; Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Sodium Azide | 1993 |
Interaction of pine cone extract fraction VI with mutagens.
Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Antimutagenic Agents; Benzo(a)pyrene; In Vitro Techniques; Lignin; Male; Methylnitronitrosoguanidine; Microsomes, Liver; Molecular Weight; Mutagenicity Tests; Plant Extracts; Rats; Rats, Sprague-Dawley | 1993 |
Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Amines; Animals; Anthracenes; Benz(a)Anthracenes; Benzo(a)pyrene; DNA Repair; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Fluorenes; Genes, Insect; Larva; Male; Methylcholanthrene; Mutagens; Polycyclic Compounds; Pyrenes; Sex Ratio | 1993 |
An evaluation of 6 chromosomal mutagens in the AS52/XPRT mutation assay utilizing suspension culture and soft agar cloning.
Topics: 2-Acetylaminofluorene; Acrylates; Aminophenols; Animals; Benzo(a)pyrene; Benzoin; Cell Line; Cloning, Molecular; Hypoxanthine Phosphoribosyltransferase; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Mutagens; Mutation; Sensitivity and Specificity | 1993 |
Evaluation of frequency of micronuclei in exfoliated cells from bladder of mice treated with benzo(a) pyrene, 2-acetylaminofluorene and cyclophosphamide.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Cell Count; Cyclophosphamide; Epithelium; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Micronucleus Tests; Urinary Bladder | 1994 |
Molecular modelling of cytochrome CYP1A1: a putative access channel explains differences in induction potency between the isomers benzo(a)pyrene and benzo(e)pyrene, and 2- and 4-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cytochrome P-450 CYP1A2; Cytochromes; Enzyme Induction; Models, Molecular | 1994 |
Effect of tissue fixation on recovery of DNA adducts in the 32P-postlabelling assay.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; DNA; DNA Adducts; DNA Damage; Evaluation Studies as Topic; Fixatives; Histological Techniques; Male; Phosphorus Radioisotopes; Rats; Rats, Wistar | 1993 |
Results of an interlaboratory trial of 32P-postlabelling.
Topics: 2-Acetylaminofluorene; Animals; Autoradiography; Benzo(a)pyrene; Butanols; Carcinogens; Chromatography, Thin Layer; DNA; DNA Adducts; Evaluation Studies as Topic; Humans; Hydrolysis; Laboratories; Lung; Male; Methods; Mice; Phosphorus Radioisotopes; Reference Standards; Reproducibility of Results; Single-Strand Specific DNA and RNA Endonucleases; Smoking | 1993 |
Methods development toward the measurement of polyaromatic hydrocarbon-DNA adducts by mass spectrometry.
Topics: 2-Acetylaminofluorene; Animals; Benzene; Benzo(a)pyrene; Carcinogens, Environmental; Chromatography, Gas; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Electrophoresis; Fluorenes; Humans; Hydrazines; Hydrogenation; Mass Spectrometry; Oxidation-Reduction; Polycyclic Compounds; Pyrenes; Spectrometry, Mass, Fast Atom Bombardment; Superoxides | 1993 |
The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases.
Topics: 2-Acetylaminofluorene; Benzo(a)pyrene; Cell Line; DNA, Complementary; Glucuronates; Glucuronosyltransferase; Humans; Hydroxylation; Microsomes, Liver | 1993 |
C18 thin-layer chromatographic enhancement of the 32P-postlabeling assay for aromatic or bulky carcinogen-DNA adducts: evaluation of adduct recoveries in comparison with nuclease P1 and butanol methods.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoquinones; Butanols; Carcinogens; Chromatography, Thin Layer; DNA; Female; Isotope Labeling; Liver; Lung; Mice; Mitomycin; Phosphorus Radioisotopes; Rats; Safrole; Single-Strand Specific DNA and RNA Endonucleases | 1993 |
Glucuronidation of carcinogen metabolites by complementary DNA-expressed uridine 5'-diphosphate glucuronosyltransferases.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Cells, Cultured; Glucuronosyltransferase; Microsomes, Liver; Rats; Substrate Specificity | 1993 |
Induction by carcinogens and chemoprevention by N-acetylcysteine of adducts to mitochondrial DNA in rat organs.
Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; DNA Adducts; DNA Damage; DNA, Mitochondrial; Male; Nicotiana; Plants, Toxic; Rats; Rats, Sprague-Dawley; Smoke | 1996 |
Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or aroclor 1254 induced rat S-9.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Humans; Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Rats | 1996 |
The detection of genotoxin-induced DNA adducts in the common mussel Mytilus edulis.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Animals; Benzo(a)pyrene; Bivalvia; DNA Adducts; Fluorenes; Liver; Models, Biological; Mutagens; Pancreas | 1997 |
Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Carcinogens; Cell Survival; DNA Adducts; DNA Damage; DNA Repair; DNA-Binding Proteins; Fibroblasts; Hypoxanthine Phosphoribosyltransferase; Male; Mice; Mice, Inbred C57BL; Mutagenesis; T-Lymphocytes; Xeroderma Pigmentosum Group A Protein | 1998 |
Mutagenesis and carcinogenesis in nucleotide excision repair-deficient XPA knock out mice.
Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Benzo(a)pyrene; Cocarcinogenesis; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Humans; Hypoxanthine Phosphoribosyltransferase; Lac Operon; Mice; Mice, Knockout; Mice, Transgenic; Models, Genetic; Mutagenesis; Neoplasms, Radiation-Induced; RNA-Binding Proteins; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein | 2000 |
In vitro detection of indirect-acting genotoxins in the comet assay using Hep G2 cells.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Biotransformation; Carcinogens; Carcinoma, Hepatocellular; Comet Assay; Cyclophosphamide; DNA Damage; DNA, Neoplasm; Humans; Image Processing, Computer-Assisted; Liver Neoplasms; Mutagens; Prodrugs; Sensitivity and Specificity; Tumor Cells, Cultured | 2000 |
Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro.
Topics: 2-Acetylaminofluorene; Base Pair Mismatch; Base Sequence; Benzo(a)pyrene; Catalysis; DNA Adducts; DNA Damage; DNA-Directed DNA Polymerase; Guanine; Humans; Mutagenesis; Mutagens; Nucleotides; Proteins; Pyrimidine Dimers; Recombinant Fusion Proteins; Substrate Specificity; Templates, Genetic | 2000 |
All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis.
Topics: 2-Acetylaminofluorene; Base Sequence; Benzo(a)pyrene; DNA Damage; DNA Polymerase beta; DNA Polymerase II; DNA Replication; DNA-Directed DNA Polymerase; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Frameshift Mutation; Mutagenesis; SOS Response, Genetics | 2000 |
Induction of sister chromatid exchanges by carcinogens mediated through cultured rat liver epithelial cells.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimetabolites; Benzo(a)pyrene; Bromodeoxyuridine; Carcinogenicity Tests; Carcinogens; Cell Line; CHO Cells; Coculture Techniques; Cricetinae; Epithelial Cells; Liver; Male; Mycotoxins; Rats; Rats, Inbred Lew; Sister Chromatid Exchange | 1980 |
Factors affecting the performance of the styles cell transformation test.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Agar; Animals; Benzo(a)pyrene; Biotransformation; Blood Physiological Phenomena; Carcinogens; Cell Count; Cell Line, Transformed; Cell Transformation, Neoplastic; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Mesocricetus; Methylnitronitrosoguanidine; Microsomes, Liver; Rats | 1980 |
Anti-mutagenic activity of Phyllanthus amarus Schum & Thonn in vitro as well as in vivo.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Antimutagenic Agents; Benzo(a)pyrene; Biotransformation; Drug Evaluation, Preclinical; In Vitro Techniques; Male; Methanol; Methylnitronitrosoguanidine; Phenylenediamines; Phyllanthus; Plant Extracts; Plant Leaves; Plant Stems; Rats; Rats, Wistar; Salmonella typhimurium; Sodium Azide; Solvents; Urine | 2002 |
Chemical models for cytochrome P450 as a biomimetic metabolic activation system in mutation assays.
Topics: 2-Acetylaminofluorene; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Activation; Ferric Compounds; Metalloporphyrins; Models, Chemical; Mutagenicity Tests; Mutagens; Mutation; Nitrosamines; Oxidants; Peroxides; Salmonella typhimurium; Solvents | 2002 |
The Liverbeads as a tool for the comet assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aged; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Comet Assay; Cyclophosphamide; DNA Damage; DNA, Neoplasm; Female; HeLa Cells; Hepatocytes; Humans; Liver; Male; Microspheres; Middle Aged; Mutagens; Prodrugs; Rats; Sensitivity and Specificity | 2002 |
Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Carcinoma, Hepatocellular; Comet Assay; Dimethylnitrosamine; Humans; Inhibitory Concentration 50; Liver Neoplasms; Methyl Methanesulfonate; Micronucleus Tests; Mutagens; Nitrosamines; Quinolones; Sensitivity and Specificity; Tumor Cells, Cultured | 2003 |
The synthesis of 3,4-benzpyrene-5-C14 and of 2-acetylaminofluorene-9-C14.
Topics: 2-Acetylaminofluorene; Benzo(a)pyrene; Benzopyrenes; Carcinogens | 1951 |
Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens.
Topics: 2-Acetylaminofluorene; Animal Testing Alternatives; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Enzymes; Female; Liver; Methylcholanthrene; Methylenebis(chloroaniline); Phenobarbital; Phosphorus Radioisotopes; Quinoxalines; Rats; Rats, Inbred F344; Rats, Wistar; Turkey | 2004 |
Toxicogenomics applied to in vitro carcinogenicity testing with Balb/c 3T3 cells revealed a gene signature predictive of chemical carcinogens.
Topics: 2-Acetylaminofluorene; Animals; BALB 3T3 Cells; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Computational Biology; Gene Expression Regulation, Neoplastic; Methylcholanthrene; Mice; Phenylenediamines; Principal Component Analysis; RNA, Messenger; Toxicogenetics | 2010 |