2-acetylaminofluorene has been researched along with aflatoxin b1 in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (44.23) | 18.7374 |
| 1990's | 20 (38.46) | 18.2507 |
| 2000's | 5 (9.62) | 29.6817 |
| 2010's | 4 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Butterworth, BE; Eldridge, SR; Gould, MN | 1 |
| Laver, GW; McMullen, E; Mehta, R; Stapley, R | 1 |
| Chen, ZY; Eaton, DL | 1 |
| Rao, MS; Reddy, JK; Sato, K; Subbarao, V | 1 |
| Cassand, P; Decoudu, S; Leveque, F; Narbonne, JF | 1 |
| Byard, JL; Dougherty, KK | 1 |
| Castelli, D; Krebs, B; Lafaurie, M; Seralini, GE; Stora, C | 1 |
| Aji, T; Arimoto, S; Hayatsu, H; Ishii, A; Matsuoka, H; Wataya, Y | 1 |
| Gebhardt, R; Tanaka, T; Williams, GM | 1 |
| Boobis, AR; Collier, N; Davies, DS; Harries, GC | 1 |
| Hsu, IC; Synder, S; Trump, BF | 1 |
| Fennell, TR; Swenberg, JA | 1 |
| Cole, KE; Hsu, IC; Jones, TW; Lipsky, MM; Trump, BF | 1 |
| Krishnaswamy, K; Rajpurohit, R | 1 |
| Maier, P; Schawalder, HP | 1 |
| Bakke, JP; Green, CE; Mirsalis, JC; Spak, DK; Steinmetz, KL | 1 |
| Clawson, GA; Ferrell, LD; Moody, DE; Smuckler, EA | 1 |
| Ahluwalia, MB; Chan, C; Farber, E; Lee, G; Roberts, E; Sarma, DS | 1 |
| Bartsch, H; Brun, G; Hautefeuille, A; Malaveille, C; Roberfroid, MB; Vo, TK | 1 |
| McNeely, M; Rascati, RJ | 1 |
| Bresil, H; Cooper, DP; Margison, GP; Montesano, R; O'Connor, PJ; Planche-Martel, G; Smith, RA | 1 |
| Hanawalt, PC; Leadon, SA | 1 |
| Carr, BI; Laishes, BA | 1 |
| Bloom, SE; Todd, LA | 1 |
| Birnbaum, LS; Robertson, IG | 1 |
| Imaida, K; Ito, N; Shirai, T; Takano, T; Tatematsu, M | 1 |
| Balwierz, PS; Oshiro, Y | 1 |
| Clawson, GA; Smuckler, EA | 1 |
| Bagnasco, M; Bennicelli, C; Bojnemirski, A; Camoirano, A; De Flora, S; Kurelec, B | 1 |
| Casciano, DA; Chou, MW; Feuers, RJ; Pegram, RA; Shaddock, JG | 1 |
| Casciano, DA; Chou, MW; Feuers, RJ; Shaddock, JG | 1 |
| al-Maskati, HA; Dairi, MG; el-Din, AY; Mohamed, AY | 1 |
| Blanck, A; Gustafsson, JA; Liao, D; Porsch-Hällström, I | 1 |
| Chen, L; Hardwick, JP | 1 |
| Beamand, JA; Lake, BG; Price, RJ; Wield, PT | 1 |
| Galloway, SM; Johnson, TE; Umbenhauer, DR | 1 |
| Berges, R; Chaumontet, C; Heberden, C; Honikman-Leban, E; Krutovskikh, VA; Le Bon, AM; Martel, P; Shahin, MM; Suschetet, M; Yamasaki, H | 1 |
| DeCicco, LA; Panzeter, PL; Ringer, DP | 1 |
| Barton, PT; Beamand, JA; Lake, BG; Price, RJ; Tredger, JM | 1 |
| Barton, PT; Beamand, JA; Lake, BG; Price, RJ | 1 |
| Barton, PT; Beamand, JA; Lake, BG; Price, RJ; Renwick, AB; Tredger, JM | 1 |
| Hamade, AK; Matsumoto, DC; Ross, MK; Said, B; Shank, RC | 1 |
| Nagy, P; Schaff, Z; Schnur, J; Sebestyén, A; Thorgeirsson, SS | 1 |
| Ross, MK; Said, B; Shank, RC | 1 |
| Gelderblom, WC; Joubert, E; Marnewick, JL | 1 |
| Ajith, TA; Joseph, S; Kuttan, R; Raphael, KR | 1 |
| Gelderblom, WC; Joubert, E; Manley, M; Marnewick, JL; Richards, ES; Snijman, PW; van der Merwe, JD | 1 |
| Gasbarrini, A; Pani, G; Petersen, BE; Piscaglia, AC; Shupe, TD; Tesori, V | 1 |
| Braunbeck, T; Broschard, TH; Huebler, N; Strecker, R; Weigt, S | 1 |
| Chaudhary, H; Jena, PK; Seshadri, S | 1 |
| Hoek-van den Hil, EF; Hollman, PCH; Keijer, J; Rietjens, IMCM; van der Stelt, I; van Schothorst, EM | 1 |
2 review(s) available for 2-acetylaminofluorene and aflatoxin b1
| Article | Year |
|---|---|
DNA damage and repair in mouse liver.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Alkylating Agents; Animals; Benzene Derivatives; Carcinogens; DNA; DNA Repair; Liver; Liver Neoplasms, Experimental; Mice; p-Aminoazobenzene; Polycyclic Compounds | 1987 |
Enhanced repair of O6-alkylguanine in mammalian tissues.
Topics: 2-Acetylaminofluorene; Adenine; Aflatoxin B1; Aflatoxins; Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Hepatectomy; Liver; Methylnitrosourea; Mice; Rats; Rodentia; Species Specificity | 1984 |
50 other study(ies) available for 2-acetylaminofluorene and aflatoxin b1
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Genotoxicity of environmental agents in human mammary epithelial cells.
Topics: 2-Acetylaminofluorene; Adult; Aflatoxin B1; Benzo(a)pyrene; Breast; DNA Repair; DNA, Neoplasm; Environmental Pollutants; Epithelial Cells; Epithelium; Female; Humans; Mutagenicity Tests; Pyrenes | 1992 |
Liver DNA adducts in methyl-deficient rats administered a single dose of aflatoxin B1.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Biotransformation; Choline Deficiency; Diet; DNA; DNA Repair; Liver; Liver Neoplasms; Liver Regeneration; Male; Methionine; Precancerous Conditions; Rats; Rats, Inbred F344 | 1992 |
Differential regulation of cytochrome(s) P450 2B1/2 by phenobarbital in hepatic hyperplastic nodules induced by aflatoxin B1 or diethylnitrosamine plus 2-acetylaminofluorene in male F344 rats.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Alkylation; Animals; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Hepatectomy; Hyperplasia; Liver; Male; Oxazines; Phenobarbital; Rats; Rats, Inbred F344; Stimulation, Chemical | 1991 |
Alterations of pancreatic hepatocytes in rats exposed to carcinogens.
Topics: 2-Acetylaminofluorene; Administration, Oral; Aflatoxin B1; Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Nucleolus; Glutathione Transferase; Hydrolyzable Tannins; Immunoenzyme Techniques; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Male; Pancreas; Phenotype; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344 | 1991 |
Relationship between vitamin A dietary intake and mutagenic activity of some chemical carcinogens.
Topics: 2-Acetylaminofluorene; Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Dose-Response Relationship, Drug; Drug Interactions; Liver; Male; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium; Vitamin A | 1990 |
Comparative metabolism and toxicity of chemical carcinogens in primary cultures of hepatocytes.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Butylated Hydroxytoluene; Carcinogens; Cells, Cultured; Culture Media; DNA; DNA Repair; Enzyme Induction; Female; Humans; Inactivation, Metabolic; Liver; Male; Mice; Mixed Function Oxygenases; Polychlorinated Dibenzodioxins; Rats; RNA | 1985 |
Ovarian function during aflatoxin B1-induced hepatocarcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Body Weight; Dietary Proteins; Estradiol; Female; Genitalia, Female; Gonads; Liver Neoplasms; Liver Neoplasms, Experimental; Ovary; Progesterone; Rats; Rats, Inbred Strains | 1986 |
Reduced levels of mutagen processing potential in the Schistosoma japonicum-infected mouse liver.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carbolines; Cytochrome P-450 Enzyme System; Female; Liver; Liver Diseases, Parasitic; Mice; Mice, Inbred C3H; Microsomes, Liver; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Schistosomiasis japonica | 1989 |
Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations.
Topics: 2-Acetylaminofluorene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Biomarkers, Tumor; Diethylnitrosamine; Glutamate-Ammonia Ligase; Immunoenzyme Techniques; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Reference Values | 1989 |
Interindividual differences in the activation of two hepatic carcinogens to mutagens by human liver.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Alkaline Phosphatase; Aryl Hydrocarbon Hydroxylases; Aspartate Aminotransferases; Bilirubin; Biotransformation; Carcinogens; Humans; In Vitro Techniques; Liver; Liver Neoplasms; Mutagenicity Tests; Subcellular Fractions | 1986 |
Comparison of metabolic activation of carcinogens in human, rat, and hamster hepatocytes.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cells, Cultured; Cricetinae; Fluorenes; Humans; Liver; Pyrenes; Rats | 1987 |
In vitro binding of aflatoxin B1 and 2-acetylaminofluorene to rat, mouse and human hepatocyte DNA: the relationship of DNA binding to carcinogenicity.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Cells, Cultured; DNA; Female; Humans; Liver; Liver Neoplasms; Male; Mice; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity | 1988 |
Differences in response of glucuronide and glutathione conjugating enzymes to aflatoxin B1 and N-acetylaminofluorene in underfed rats.
Topics: 2-Acetylaminofluorene; Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hydroxylases; Body Weight; Cytochrome P-450 Enzyme System; Food Deprivation; Glutathione Transferase; Liver; Male; Organ Size; Rats; Rats, Inbred Strains; UTP-Glucose-1-Phosphate Uridylyltransferase | 1988 |
Hepatocarcinogens induce gene mutations in rats in fibroblast-like cells from a subcutaneous granulation tissue.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Fibroblasts; Granulation Tissue; Liver Neoplasms, Experimental; Male; Mutation; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Vinyl Chloride | 1988 |
Induction of unscheduled DNA synthesis in primary cultures of rat, mouse, hamster, monkey, and human hepatocytes.
Topics: 2-Acetylaminofluorene; Adult; Aflatoxin B1; Aflatoxins; Aminobiphenyl Compounds; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cricetinae; Dimethyl Sulfoxide; DNA; DNA Repair; Female; Haplorhini; Humans; Liver; Male; Mice; Rats; Species Specificity | 1988 |
Increased nucleoside triphosphatase activity of rat liver nuclear envelope is associated with hepatocarcinogen exposure.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biological Transport; Carbon Tetrachloride Poisoning; Carcinogens; Dimethylnitrosamine; Kinetics; Liver; Male; Methyldimethylaminoazobenzene; Nuclear Envelope; Nucleoside-Triphosphatase; Phosphoric Monoester Hydrolases; Phosphorylation; Rats; Rats, Inbred Strains; RNA; Thioacetamide | 1984 |
Resistance to hepatotoxins acquired by hepatocytes during liver regeneration.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Cells, Cultured; Drug Resistance; Hydroxyacetylaminofluorene; Liver; Liver Regeneration; Male; Methotrexate; Methyl Methanesulfonate; Rats; Rats, Inbred F344; Time Factors | 1983 |
Interrelationships in mice of antipyrine half-life, hepatic monooxygenase activities and liver S9-mediated mutagenicity of aflatoxin B1, benzo[alpha]pyrene 7,8-dihydrodiol, 2-acetylaminofluorene and N-nitrosomorpholine.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Antipyrine; Benzopyrenes; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Female; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutagens; Nitrosamines; Oxygenases | 1983 |
Induction of retrovirus gene expression by aflatoxin B1 and 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Line; Cells, Cultured; Clone Cells; Embryo, Mammalian; Fibroblasts; Genes, Viral; Mice; Mice, Inbred AKR; Microsomes, Liver; Mutagens; Mutation; Rats; Retroviridae | 1983 |
Ultraviolet irradiation of monkey cells enhances the repair of DNA adducts in alpha DNA.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Chlorocebus aethiops; DNA; DNA Repair; Protein Biosynthesis; Sulfuric Acid Esters; Ultraviolet Rays | 1984 |
Carcinogen-induced drug resistance in rat hepatocytes.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Cell Cycle; Cell Survival; Cells, Cultured; Cycloheximide; Doxorubicin; Drug Resistance; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methotrexate; Rats | 1981 |
Differential induction of sister chromatid exchanges by indirect-acting mutagen-carcinogens at early and late stages of embryonic development.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Chick Embryo; Crossing Over, Genetic; Ethyl Methanesulfonate; Mitotic Index; Mutagens; Sister Chromatid Exchange | 1980 |
Age-related changes in mutagen activation by rat tissues.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Aging; Animals; Biotransformation; Female; Fluorenes; Kidney; Liver; Lung; Rats | 1982 |
Dose responses of five hepatocarcinogens for the initiation of rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hepatectomy; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; p-Dimethylaminoazobenzene; Rats | 1981 |
Morphological transformation of C3H/10T1/2 CL8 cells by procarcinogens.
Topics: 2-Acetylaminofluorene; 2-Naphthylamine; 4-Nitroquinoline-1-oxide; Aflatoxin B1; Aflatoxins; Animals; Benz(a)Anthracenes; Biotransformation; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Embryo, Mammalian; Mice; Time Factors | 1982 |
Increased amounts of double-stranded RNA in the cytoplasm of rat liver following treatment with carcinogens.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cytoplasm; Dimethylnitrosamine; Liver; Male; Rats; Rats, Inbred Strains; RNA, Double-Stranded | 1982 |
Biotransformation of genotoxic agents in marine sponges. Mechanisms and modulation.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Benzo(a)pyrene; Biotransformation; Carbolines; Glutathione; Glutathione Disulfide; Glutathione Transferase; Inactivation, Metabolic; Microsomes, Liver; Mutagens; Porifera; Quinolines; Rats; Salmonella typhimurium; Species Specificity; Vincristine | 1995 |
Effects of aging and caloric restriction on the genotoxicity of four carcinogens in the in vitro rat hepatocyte/DNA repair assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aging; Animals; Dimethylnitrosamine; DNA Repair; Energy Intake; Food Deprivation; Liver; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred F344 | 1993 |
Evidence that DNA repair may not be modified by age or chronic caloric restriction.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aging; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Diet; Dimethylnitrosamine; DNA; DNA Repair; Energy Intake; Enzyme Induction; Food Deprivation; Liver; Male; Mixed Function Oxygenases; Mutagens; Rats; Rats, Inbred F344 | 1993 |
Acrylamide as an inducer of metabolic activation system (S9) in rats.
Topics: 2-Acetylaminofluorene; Acrylamide; Acrylamides; Aflatoxin B1; Animals; Azides; Benzo(a)pyrene; Biotransformation; Dose-Response Relationship, Drug; Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Sodium Azide | 1993 |
Sex differences at the initiation stage of rat liver carcinogenesis--influence of growth hormone.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Female; Growth Hormone; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Rats; RNA, Messenger; Sex Characteristics; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1993 |
Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Amino Acid Sequence; Animals; Antisense Elements (Genetics); Base Sequence; Blotting, Northern; Blotting, Western; Clofibrate; Cytochrome P-450 Enzyme System; Humans; Liver Neoplasms; Male; Microsomes; Molecular Sequence Data; Multigene Family; Rats; Sequence Homology, Amino Acid | 1993 |
Use of precision-cut liver slices to evaluate species differences in 2-acetylaminofluorene-induced unscheduled DNA synthesis.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Antineoplastic Agents; Blotting, Western; Chrysenes; Cytochrome P-450 Enzyme System; DNA Damage; DNA Replication; Guinea Pigs; Humans; In Vitro Techniques; Liver; Macaca fascicularis; Male; Rats; Rats, Sprague-Dawley; Species Specificity | 1996 |
Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or aroclor 1254 induced rat S-9.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Humans; Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Rats | 1996 |
Lack of tumor-promoting effects of flavonoids: studies on rat liver preneoplastic foci and on in vivo and in vitro gap junctional intercellular communication.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinogens; Cell Line; Cricetinae; Flavanones; Flavones; Flavonoids; Gap Junctions; Glutathione Transferase; Hepatectomy; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Quercetin; Rats; Rats, Wistar | 1996 |
Alterations in epidermal growth factor binding to hepatic membranes following dietary exposure of rats to known hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aniline Compounds; Animals; Benzidines; Binding Sites; Carcinogens; Epidermal Growth Factor; Ethionine; Fluorenes; Food Deprivation; Male; Methylcholanthrene; Methyldimethylaminoazobenzene; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thioacetamide | 1997 |
Effect of some cooked food mutagens on unscheduled DNA synthesis in cultured precision-cut rat, mouse and human liver slices.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Autoradiography; Carbolines; Cooking; Culture Techniques; DNA; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Liver; Male; Mice; Mutagens; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1998 |
Lack of effect of coumarin on unscheduled DNA synthesis in precision-cut human liver slices.
Topics: 2-Acetylaminofluorene; Adolescent; Aflatoxin B1; Antineoplastic Agents; Carcinogens; Child; Child, Preschool; Coumarins; Cytochrome P-450 Enzyme System; DNA; DNA Replication; Female; Humans; Imidazoles; In Vitro Techniques; Liver; Male; Protein Biosynthesis | 1998 |
Inhibition of xenobiotic-induced genotoxicity in cultured precision-cut human and rat liver slices.
Topics: 2-Acetylaminofluorene; Adult; Aflatoxin B1; Animals; Carcinogens; Child; Child, Preschool; DNA; DNA Repair; Female; Flavanones; Flavones; Flavonoids; Humans; Imidazoles; In Vitro Techniques; Liver; Male; Microsomes, Liver; Middle Aged; Mutagenicity Tests; Rats; Rats, Sprague-Dawley; Xenobiotics | 1999 |
DNA-damaging effects of genotoxins in mixture: nonadditive effects of aflatoxin B1 and N-acetylaminofluorene on their mutagenicity in Salmonella typhimurium.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Aflatoxin B1; Alleles; DNA Damage; Frameshift Mutation; Mutagenicity Tests; Mutagens; Salmonella typhimurium | 1999 |
Chemical hepatocarcinogenesis in transgenic mice overexpressing mature TGF beta-1 in liver.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinogens; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Transforming Growth Factor beta | 1999 |
DNA-damaging effects of genotoxins in mixture: modulation of covalent binding to DNA.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Binding, Competitive; Cattle; DNA; DNA Adducts; DNA Damage; Guanine; Mutagens; Sulfuric Acid Esters | 2000 |
An investigation on the antimutagenic properties of South African herbal teas.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Antimutagenic Agents; Beverages; Microsomes, Liver; Mutagenesis; Mutagenicity Tests; Mutagens; Phytotherapy; Salmonella typhimurium | 2000 |
Anti-mutagenic activity of Phyllanthus amarus Schum & Thonn in vitro as well as in vivo.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Antimutagenic Agents; Benzo(a)pyrene; Biotransformation; Drug Evaluation, Preclinical; In Vitro Techniques; Male; Methanol; Methylnitronitrosoguanidine; Phenylenediamines; Phyllanthus; Plant Extracts; Plant Leaves; Plant Stems; Rats; Rats, Wistar; Salmonella typhimurium; Sodium Azide; Solvents; Urine | 2002 |
A comparative study on the antimutagenic properties of aqueous extracts of Aspalathus linearis (rooibos), different Cyclopia spp. (honeybush) and Camellia sinensis teas.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Antimutagenic Agents; Aspalathus; Camellia sinensis; Fabaceae; Flavonoids; Mutagenesis; Mutagenicity Tests; Mutagens; Phenols; Plant Extracts; Polyphenols; Salmonella typhimurium | 2006 |
Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cholangiocarcinoma; Granulocyte Colony-Stimulating Factor; Hepatectomy; Hepatocyte Growth Factor; Liver Neoplasms; Male; Neoplasm Metastasis; Proto-Oncogene Proteins c-met; Rats; Rats, Inbred F344; Receptors, Granulocyte Colony-Stimulating Factor | 2009 |
Zebrafish (Danio rerio) embryos as a model for testing proteratogens.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carbamazepine; Cinnarizine; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Combinations; Ifosfamide; Mutagenicity Tests; Ovum; Piracetam; Tegafur; Teratogens; Thiotepa; Trimethadione; Zebrafish | 2011 |
Evaluation of hydro-alcoholic extract of Eclipta alba for its multidrug resistance reversal potential: an in vitro study.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Proliferation; Chromatography, High Pressure Liquid; Doxorubicin; Drug Resistance, Neoplasm; Eclipta; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liquid-Liquid Extraction; Liver Neoplasms; Neoplasms; Plant Extracts; Transfection; Xenobiotics | 2013 |
Quercetin tests negative for genotoxicity in transcriptome analyses of liver and small intestine of mice.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Diet, High-Fat; Dietary Supplements; DNA Damage; Gene Expression Profiling; Intestine, Small; Liver; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Quercetin; Up-Regulation | 2015 |