Compounds > 2-acetylaminofluorene
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2-acetylaminofluorene and acetylcysteine

2-acetylaminofluorene has been researched along with acetylcysteine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Cesarone, CF; D'Agostini, F; Perrone, MC; Serra, D1
Cesarone, CF; Orunesu, M; Scarabelli, L1
Geeroms, D; Mainguet, P; Roberfroid, M; Wilpart, M1
Bagnasco, M; Balansky, RM; Cesarone, CF; D'Agostini, F; De Flora, S; Izzotti, A; Rovida, A; Scatolini, L1
Balansky, R; D'Agostini, F; De Flora, S; Izzotti, A; Scatolini, L1
Claret, FX; Deng, L; Kuo, MT; Lin-Lee, YC1
Fardel, O; Guillouzo, A; Huc, L; Lagadic-Gossmann, D; Loewert, M; Payen, L; Sparfel, L1
Balansky, RM; De Flora, S1
Satoh, K1

Reviews

1 review(s) available for 2-acetylaminofluorene and acetylcysteine

ArticleYear
Chemoprevention of carcinogen-DNA adducts and chronic degenerative diseases.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Anticarcinogenic Agents; Aorta, Abdominal; Arteriosclerosis; Carcinogens; Cricetinae; Diet; DNA; Humans; Male; Mice; Rats; Rats, Sprague-Dawley; Rats, Wistar; Smoke; Smoking

1994

Other Studies

9 other study(ies) available for 2-acetylaminofluorene and acetylcysteine

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
[Evaluation of blood chemistry parameters of rats treated with 2-acetylaminofluorene and N-acetylcysteine].
    Bollettino della Societa italiana di biologia sperimentale, 1991, Volume: 67, Issue:9

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Blood Proteins; Chemical and Drug Induced Liver Injury; Lipids; Liver Function Tests; Male; Rats; Rats, Inbred Strains

1991
Effect of glutathione and N-acetylcysteine on hepatocellular modifications induced by 2-acetylaminofluorene.
    Toxicologic pathology, 1986, Volume: 14, Issue:4

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; DNA; Drug Interactions; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; Salivary Gland Neoplasms

1986
Desmutagenic effects of N-acetylcysteine on direct and indirect mutagens.
    Mutation research, 1985, Volume: 142, Issue:4

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Anthracenes; Azides; Benzo(a)pyrene; Biotransformation; Dose-Response Relationship, Drug; Fluorenes; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Sodium Azide

1985
Induction by carcinogens and chemoprevention by N-acetylcysteine of adducts to mitochondrial DNA in rat organs.
    Cancer research, 1996, Apr-01, Volume: 56, Issue:7

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; DNA Adducts; DNA Damage; DNA, Mitochondrial; Male; Nicotiana; Plants, Toxic; Rats; Rats, Sprague-Dawley; Smoke

1996
2-acetylaminofluorene up-regulates rat mdr1b expression through generating reactive oxygen species that activate NF-kappa B pathway.
    The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Carcinogens; DNA; DNA-Binding Proteins; Enzyme Activation; Flow Cytometry; Gene Expression Regulation; Genes, Reporter; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; NF-kappa B; Oxidative Stress; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Rats; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Transfection; Tumor Cells, Cultured; Up-Regulation

2001
Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells.
    Toxicology letters, 2002, Mar-28, Volume: 129, Issue:3

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Apoptosis; Benzoflavones; Blotting, Northern; Carcinogens; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Hepatocytes; Rats; RNA, Messenger

2002
Interactions between N-acetylcysteine and sodium selenite in modulating the clastogenicity of urethane and 2-acetylaminofluorene in mice.
    International journal of cancer, 2004, Jan-01, Volume: 108, Issue:1

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Antimutagenic Agents; Drug Interactions; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred BALB C; Micronucleus Tests; Sodium Selenite; Urethane

2004
Strong carcinogenic stress response induction of preneoplastic cells positive for GST-P in the rat liver: Physiological mechanism for initiation.
    Life sciences, 2018, May-01, Volume: 200

    Topics: 2-Acetylaminofluorene; Acetylcysteine; Animals; Bile Ducts; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Hepatectomy; Hepatocytes; Liver Neoplasms; Male; Neoplasm Proteins; Precancerous Conditions; Rats; Rats, Sprague-Dawley

2018