2-acetylaminofluorene has been researched along with acetoxyacetylaminofluorene in 122 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 114 (93.44) | 18.7374 |
| 1990's | 6 (4.92) | 18.2507 |
| 2000's | 2 (1.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jurs, PC; Yuta, K | 1 |
| Kriek, E | 1 |
| Lieberman, MW; Roberts, JD | 1 |
| Dreux, M; Leng, M; Saint-Ruf, G; Spodheim-Maurizot, M | 1 |
| Amacher, DE; Elliott, JA; Lieberman, MW | 1 |
| de Murcia, G; Duane, MP; Freund, AM; Fuchs, RP; Lang, MC; Leng, M; Sage, E | 1 |
| Bhattacharya, PK; Kubinski, H; Kubinski, ZO; Morin, NR; Zeldin, PE | 1 |
| Dubin, MA; Poirier, MC; Yuspa, SH | 1 |
| Custer, RP; Sorof, S; Tonelli, QJ | 1 |
| Austin, GE; Moyer, GH | 1 |
| Kriek, E; Spelt, CE | 1 |
| Daune, MP; de Murcia, G; Freund, AM; Fuchs, RP; Lang, MC | 1 |
| Miller, JA; Yager, JD | 1 |
| Gutmann, HR; Malejka-Giganti, D; Rydell, RE | 1 |
| Leffler, S; Weinstein, IB; Yamasaki, H | 1 |
| MacKinney, AA; Vyas, R | 1 |
| Gupta, PK; King, CM; Lee, MS; Pandrangi, RG | 1 |
| Anderson, MW; Anna, CH; Bryngelsson, C; Doyle, GA; Markowitz, M; Pero, RW; Romagna, F | 1 |
| Bintz, R; Fuchs, RP | 1 |
| Huitfeldt, H; Olivero, OA; Poirier, MC | 1 |
| Carothers, AM; Chasin, LA; Grunberger, D; Steigerwalt, RW; Urlaub, G | 2 |
| Black, KA; Grisham, JW; McFarland, RD; Smith, GJ | 1 |
| King, CM; Mah, MC; Maher, VM; McCormick, JJ; Reid, TM; Thomas, H | 1 |
| Fuchs, RP; Koffel-Schwartz, N | 1 |
| Bohr, VA; Hanawalt, PC; Pierce, J; Tang, MS; Zhang, XS | 1 |
| Harris, C; Juchau, MR; Stark, KL | 1 |
| Lund-Pero, M; Miller, DG; Pero, RW | 2 |
| Armier, J; Fuchs, RP; Leng, M; Mezzina, M; Sarasin, A | 1 |
| Bases, R; Davidson, A; Mendez, F | 1 |
| Gentil, A; Margot, A; Sarasin, A | 1 |
| Beard, P; Brown, TC; Cerutti, PA | 1 |
| Popanda, O; Thielmann, HW | 1 |
| Kohwi, Y; Kohwi-Shigematsu, T; Scribner, N | 1 |
| Beland, FA; Casciano, DA; Djurić, Z; Fullerton, NF; Heflich, RH; Zhuo, Z | 1 |
| Adair, GM; Humphrey, RM; Nairn, RS; Tang, MS; Wang, RM | 1 |
| Gutmann, HR; Smith, BA; Springfield, JR | 2 |
| Daune, MP; Fuchs, RP; Granger-Schnarr, M | 1 |
| Arce, GT; Cline, DT; Mead, JE | 1 |
| Fukui, S; Hirai, K; Hirayama, T; Ogawa, S; Tokuda, M | 1 |
| Ball, SS; Quaranta, V; Shadravan, F; Walford, RL | 1 |
| Gustafsson, JA; Möller, L; Rafter, J | 1 |
| Hebert, E; Leng, M; Marrot, L; Saint-Ruf, G | 1 |
| Faustman-Watts, EM; Juchau, MR; Namkung, MJ | 1 |
| Glatt, H; Oesch, F | 1 |
| Baan, RA; Lohman, PH; Muysken-Schoen, MA | 1 |
| Grantham, PH; Hankins, WD; Roller, PP; Thorgeirsson, SS; Vu, VT; Wirth, PJ | 1 |
| Daune, MP; Fuchs, RP; Koffel-Schwartz, N; Westhof, E | 1 |
| Krugh, TR; Sanford, DG | 1 |
| Grantham, PH; Møller, ME; Thorgeirsson, SS; Vu, VT; Wirth, PJ | 1 |
| Box, HC; Sharma, M | 1 |
| Kourilsky, P; Le Guern, A; Leng, M | 1 |
| Loukakou, PE; Saint-Ruf, G; Spodheim-Maurizot, M | 1 |
| Dixon, K; Maga, JA | 1 |
| Fantel, AG; Faustman-Watts, EM; Greenaway, JC; Juchau, MR; Namkung, MJ; Yang, HY | 1 |
| Baan, RA; Hoeijmakers, JH; Jasen in de Wal, N; Landegent, JE; Van der Ploeg, M | 1 |
| Bases, R; Mendez, F; Mendez, L | 1 |
| Loman, H; Lutgerink, JT; Retèl, J | 1 |
| Beard, P; Cerutti, P; Kaneko, M | 1 |
| Babich, M; Coohill, TP; Snipes, W; Taylor, WD | 1 |
| Lieberman, MW; Tang, M | 1 |
| Jonsson, GG; Pero, RW; Persson, L | 1 |
| Baan, RA; Hoeijmakers, JH; Landegent, JE; Raap, AK; Van der Ploeg, M | 1 |
| Little, JB; Zimmerman, RJ | 3 |
| Daune, MP; Fuchs, RP; Schwartz, N | 2 |
| Rayshell, M; Ross, J; Werbin, H | 1 |
| Daune, M; Freund, AM; Fuchs, RP; Lang, MC; Paoletti, C; Salles, B | 1 |
| Luisi-DeLuca, C; Porter, RD; Taylor, WD | 1 |
| Fuchs, RP; Seeberg, E | 1 |
| Bichara, M; Daune, MP; Freund, AM; Fuchs, RP; Koffel-Schwartz, N; Verdier, JM | 1 |
| Moore, PD; Rabkin, SD; Strauss, BS | 1 |
| Hedner, K; Mitelman, F; Pero, RW | 1 |
| Alderfer, JL; Box, HC; French, J; Lilga, KT | 1 |
| Marshall, MV; Purdy, RH | 1 |
| Hedner, K; Iselius, L; Mitelman, F; Nordén, A; Pero, RW | 1 |
| Bryngelsson, C; Bryngelsson, T; Franzén, J; Janzon, L; Johansson, BW; Lindholm, L; Pero, RW; Scherstén, B; Trell, E | 1 |
| Durand, M; Loukakou, PE; Saint-Ruf, G; Spodheim-Maurizot, M | 1 |
| Boehm, TL; Drahovsky, D; Grunberger, D | 1 |
| Bryngelsson, C; Bryngelsson, T; Nordén, A; Pero, RW | 1 |
| Beland, FA; Melchior, WB | 1 |
| Glowinski, IB; Møller, ME; Thorgeirsson, SS | 1 |
| Chessebeuf, M; Exilie-Frigere, MF; Padieu, P; Wood, G | 1 |
| Fuchs, RP | 1 |
| Hecht, R; Thielmann, HW | 1 |
| Grunberger, D; Pulkrabek, P; Singer, B; Weinstein, IB | 1 |
| Ahmed, FE; Setlow, RB | 1 |
| Fraenkel-Conrat, H; Grunberger, D; Santella, RM; Singer, B; Takanami, Y | 1 |
| Hemminki, K | 1 |
| Dirheimer, G; Fuchs, RP; Keith, G; Pfohl-Leszkowicz, A | 1 |
| Lund-Pero, M; Pero, RW | 1 |
| Laishes, BA; Poirier, MC; True, B; Yuspa, SH | 1 |
| Kuhnlein, U; Tsang, SS | 1 |
| Leng, M; Sage, E | 2 |
| Barbin, A; Bartsch, H; Brun, G; Camus, AM; Drevon, C; Hautefeuille, A; Kuroki, T; Malaveille, C; Martel-Planche, G; Montesano, R; Piccoli, C; Sabadie, N | 1 |
| Daune, M; de Murcia, G; Fuchs, RP; Lang, MC; Leng, M; Mazen, A | 1 |
| Daune, MP; Fuchs, RP; Schmid, SE | 1 |
| Pero, RW; Sjögren, HO | 1 |
| Miller, EC; Miller, JA; Tarpley, WG | 1 |
| Chou, RH; Cohn, SM; Lieberman, MW; Tang, MS | 1 |
| Malfoy, B; Saint-Ruf, G; Spodheim-Maurizot, M | 1 |
| Daune, M; Fuchs, RP; Hélène, C; Toulmé, F | 1 |
| Bobst, AM; Cerutti, PA; Wang, TV | 1 |
| Austin, GE; Moyer, GH; Van Roy, FP | 1 |
| Scribner, JD | 1 |
| Kuhn, C; Thielmann, HW | 1 |
| Niles, R; Smith, BD | 1 |
| Becker, FF; Chan, JY | 1 |
| D'Ambrosio, SM; Setlow, RB | 1 |
| Remsen, JF | 1 |
| Poirier, MC; Williams, GM; Yuspa, SH | 1 |
| Ostlund, C; Pero, RW | 1 |
| Cerutti, PA; Kaneko, M | 1 |
| Ho, YS; Lin, JK | 1 |
| Hamade, AK; Matsumoto, DC; Ross, MK; Said, B; Shank, RC | 1 |
| Kuo, MT; Lin-Lee, YC; Liu, Z; Mills, GB; Tatebe, S; Unate, H; Wei, Y | 1 |
| Liao, Q; Shen, C; Vouros, P | 1 |
2 review(s) available for 2-acetylaminofluorene and acetoxyacetylaminofluorene
| Article | Year |
|---|---|
Macromolecular complexes produced by chemical carcinogens and ultraviolet radiation.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Albumins; Alkylating Agents; Carcinogens; Centrifugation, Isopycnic; Chemical Phenomena; Chemistry; Chromatography, Gel; DNA; Ethyl Methanesulfonate; Hydroxyacetylaminofluorene; In Vitro Techniques; Mechlorethamine; Methyl Methanesulfonate; Muramidase; Proteins; RNA; Ultraviolet Rays | 1977 |
Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Alkylating Agents; Animals; Benzopyrenes; Biotransformation; Carcinogens; Cell Line; Cricetinae; Cricetulus; Dichloroethylenes; Drug Evaluation, Preclinical; Environmental Pollutants; Female; Fibroblasts; Fluorenes; Humans; Male; Mesocricetus; Microsomes, Liver; Mutagens; Nitrosamines; Rats; Salmonella typhimurium; Species Specificity; Vinyl Chloride | 1980 |
120 other study(ies) available for 2-acetylaminofluorene and acetoxyacetylaminofluorene
| Article | Year |
|---|---|
Computer-assisted structure-activity studies of chemical carcinogens. Aromatic amines.
Topics: Amines; Animals; Binding Sites; Carcinogens; Computers; Pattern Recognition, Automated; Rats; Structure-Activity Relationship | 1981 |
Effect of pH on the ratio of substitution products in DNA after reaction with the carcinogen N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; DNA; Guanine; Hydrogen-Ion Concentration | 1979 |
Deoxyribonucleic acid repair synthesis in permeable human fibroblasts exposed to ultraviolet radiation and N-acetoxy-2-(acetylamino)fluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Cell Line; DNA; DNA Repair; Fibroblasts; Humans; Hydrogen-Ion Concentration; Kinetics; Permeability; Ultraviolet Rays; Xeroderma Pigmentosum | 1979 |
Alkaline stability of guanosine and some of its derivatives modified by the carcinogen N-acetoxyacetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Circular Dichroism; Drug Stability; Guanosine; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation; Structure-Activity Relationship | 1979 |
Differences in removal of acetylaminofluorene and pyrimidine dimers from the DNA of cultured mammalian cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Cell Aggregation; Cell Line; DNA Repair; DNA Replication; Fibroblasts; Fluorenes; Kinetics; Pyrimidine Dimers; Ultraviolet Rays | 1977 |
Electron microscopic visualization of N-acetoxy-N-2-acetylaminofluorene binding sites in ColE1 DNA by means of specific antibodies.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacteriocin Plasmids; Base Sequence; Binding Sites; Deoxyguanine Nucleotides; DNA, Bacterial; Electrophoresis, Agar Gel | 1979 |
Formation and removal of specific acetylaminofluorene-DNA adducts in mouse and human cells measured by radioimmunoassay.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Acetylation; Animals; Cells, Cultured; Deoxyguanosine; DNA; Fluorenes; Humans; Mice; Radioimmunoassay; Skin | 1979 |
Transformation of cultured mouse mammary glands by aromatic amines and amides and their derivatives.
Topics: 1-Naphthylamine; 2-Acetylaminofluorene; 2-Naphthylamine; Acetoxyacetylaminofluorene; Animals; Cell Transformation, Neoplastic; Female; Fluorenes; Hydroxyacetylaminofluorene; Mammary Neoplasms, Experimental; Mice; Naphthalenes; Organ Culture Techniques | 1979 |
Inhibition of RNA synthesis by derivatives of the carcinogen 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cell Nucleus; DNA; DNA-Directed RNA Polymerases; Fluorenes; Male; Rats; RNA; RNA Polymerase I; RNA Polymerase II; Transcription, Genetic | 1979 |
Differential excision from DNA of the C-8 deoxyguanosine reaction products of N-hydroxy-2-aminofluorene and N-acetoxy-N-acetyl-2-aminofluorene by endonuclease S1 from Aspergillus oryzae.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Aspergillus oryzae; Deoxyguanosine; DNA; Endonucleases; Fluorenes; Hydroxylamines; Kinetics; Nucleic Acid Conformation; Nucleic Acid Denaturation | 1979 |
Unwinding of supercoiled Col E1-DNA after covalent binding of the ultimate carcinogen N-acetoxy-N-2-acetylaminofluorene and its 7-iodo derivative.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chemical Phenomena; Chemistry; DNA, Superhelical; Electrophoresis, Agar Gel; Microscopy, Electron | 1979 |
DNA repair in primary cultures of rat hepatocytes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cells, Cultured; DNA; DNA Repair; Fluorenes; Hydroxyacetylaminofluorene; Liver; Male; Rats; Thymidine; Ultraviolet Rays | 1978 |
Mammary carcinogenesis in the rat by topical application of fluorenylhydroxamic acids and their acetates.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Acetylation; Administration, Topical; Animals; Cytochrome P-450 Enzyme System; Estradiol; Female; Fluorenes; Hydroxyacetylaminofluorene; Hydroxylation; Mammary Neoplasms, Experimental; Microsomes; Microsomes, Liver; Ovary; Rats | 1977 |
Effect of N-2-acetylaminofluorene modification on the structure and template activity of DNA and reconstituted chromatin.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; Binding Sites; Chromatin; Deoxyribonucleases; DNA; Fluorenes; In Vitro Techniques; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Transcription, Genetic | 1977 |
Effects of 5,5-diphenylhydantoin and related carbamates and hydroxylamines on nucleic acid and protein synthesis of proliferating human lymphocytes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Blood Proteins; Carbamates; DNA; Humans; Hydantoins; Hydroxyacetylaminofluorene; Hydroxylamines; In Vitro Techniques; Leucine; Lymphocytes; Phenytoin; Structure-Activity Relationship; Thymidine | 1975 |
Induction of mutations by N-acetoxy-N-acetyl-2-aminofluorene modified M13 viral DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; Coliphages; Deoxyguanosine; DNA, Viral; Frameshift Mutation; Molecular Sequence Data; Mutation; Plasmids; SOS Response, Genetics; Transfection | 1991 |
Oxidative stress induces DNA damage and inhibits the repair of DNA lesions induced by N-acetoxy-2-acetylaminofluorene in human peripheral mononuclear leukocytes.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Acetoxyacetylaminofluorene; Antigens, Differentiation, T-Lymphocyte; DNA; DNA Damage; DNA Repair; DNA Replication; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Leukocytes; Nitroquinolines; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Tetradecanoylphorbol Acetate | 1990 |
Induction of -2 frameshift mutations within alternating GC sequences by carcinogens that bind to the C8 position of guanine residues: development of a specific mutation assay.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Composition; Base Sequence; Carcinogens; DNA, Bacterial; Escherichia coli; Mutagenicity Tests; Mutation; Nucleic Acid Conformation; Plasmids | 1990 |
Chromosome site-specific immunohistochemical detection of DNA adducts in N-acetoxy-2-acetylaminofluorene--exposed Chinese hamster ovary cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Bromodeoxyuridine; Cell Line; Chromosome Banding; Chromosomes; Cricetinae; DNA; DNA Damage; DNA Replication; Immunohistochemistry; Interphase | 1990 |
DNA base changes and RNA levels in N-acetoxy-2-acetylaminofluorene-induced dihydrofolate reductase mutants of Chinese hamster ovary cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Sequence; Cricetinae; DNA; Female; Molecular Sequence Data; Mutation; Nucleic Acid Heteroduplexes; Ovary; Polymerase Chain Reaction; Restriction Mapping; RNA; Tetrahydrofolate Dehydrogenase | 1989 |
S-phase block and cell death in human lymphoblasts exposed to benzo[a]pyrene diol epoxide or N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetoxyacetylaminofluorene; Cell Survival; Dihydroxydihydrobenzopyrenes; DNA Replication; Dose-Response Relationship, Drug; Humans; Interphase; Lymphocytes | 1989 |
Mutations induced by aminofluorene-DNA adducts during replication in human cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacterial Proteins; Base Sequence; Carcinogens; Cell Line; Chromosome Deletion; DNA, Bacterial; Genes, Bacterial; Humans; Kidney; Molecular Sequence Data; Mutation; Plasmids; Transfection | 1989 |
Genetic control of AAF-induced mutagenesis at alternating GC sequences: an additional role for RecA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; Escherichia coli; Genes, Bacterial; Genotype; Mutation; Phenotype; Plasmids; Rec A Recombinases | 1989 |
Quantification of aminofluorene adduct formation and repair in defined DNA sequences in mammalian cells using the UVRABC nuclease.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Sequence; Cell Line; Cricetinae; Cricetulus; DNA; DNA Adducts; DNA Damage; DNA Repair; Endodeoxyribonucleases; Escherichia coli Proteins; Female; Fluorenes; Formamides; Nucleic Acid Denaturation; Ovary; Tetrahydrofolate Dehydrogenase | 1989 |
Influence of electrophilic character and glutathione depletion on chemical dysmorphogenesis in cultured rat embryos.
Topics: 2-Acetylaminofluorene; Acetaminophen; Acetoxyacetylaminofluorene; Animals; Biotransformation; Embryo, Mammalian; Fetal Proteins; Glutathione; Morphogenesis; Rats; Rats, Inbred Strains | 1989 |
The nonspecific esterases of human mononuclear leukocytes metabolize arylamine carcinogens and steroids esters.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Beclomethasone; DNA; DNA Damage; Esterases; Humans; Kinetics; Leukocytes, Mononuclear; Substrate Specificity | 1989 |
N-acetoxy-N-2-acetylaminofluorene-induced damage on SV40 DNA: inhibition of DNA replication and visualization of DNA lesions.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; DNA Damage; DNA Replication; DNA, Viral; Guanine; Immunoglobulin Fab Fragments; Microscopy, Electron; Simian virus 40 | 1988 |
IgG binding enhances DNAase I sensitivity of N-acetoxy-N-2-acetylaminofluorene-modified phi X-174 RF DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Antigen-Antibody Complex; Bacteriophage phi X 174; Deoxyribonuclease I; DNA Restriction Enzymes; DNA, Viral; Humans; Immunoglobulin G; Kinetics; Phosphorus Radioisotopes; Primates; Staphylococcal Protein A | 1985 |
Characterization of mutations induced by 2-(N-acetoxy-N-acetyl)aminofluorene in the dihydrofolate reductase gene of cultured hamster cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Sequence; Cell Line; Chemical Phenomena; Chemistry; Chromosome Deletion; Cricetinae; DNA; DNA Restriction Enzymes; Guanine; Mutation; Tetrahydrofolate Dehydrogenase | 1986 |
2-(N-acetoxy-N-acetylamino)fluorene mutagenesis in mammalian cells: sequence-specific hot spot.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Sequence; Cell Line; Chlorocebus aethiops; DNA Damage; DNA Replication; DNA, Viral; Mutation; Simian virus 40 | 1986 |
Preferential repair of N-acetoxy-acetylaminofluorene lesions in the nuclease-hypersensitive region of simian virus 40.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cell Line; Chlorocebus aethiops; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; DNA Repair; DNA Restriction Enzymes; DNA, Viral; Simian virus 40 | 1987 |
Comparison of DNA-incising capacities in fibroblast strains from the Mannheim XP collection after treatment with N-acetoxy-2-acetylaminofluorene and UV light.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Cells, Cultured; DNA; DNA Damage; Fibroblasts; Humans; Ultraviolet Rays; Xeroderma Pigmentosum | 1988 |
An ultimate chemical carcinogen, N-acetoxy-2-acetylaminofluorene, detects non-B DNA structures that are reactive with chloroacetaldehyde in supercoiled plasmid DNA.
Topics: 2-Acetylaminofluorene; Acetaldehyde; Acetoxyacetylaminofluorene; Base Sequence; DNA, Superhelical; Magnesium; Nucleic Acid Conformation; Plasmids | 1988 |
Metabolism of 2-acetylaminofluorene in the Chinese hamster ovary cell mutation assay.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Acetyl Coenzyme A; Acetylation; Animals; Biotransformation; Cell Line; Cricetinae; Cricetulus; Cytosol; DNA Damage; Female; Fibroblasts; Fluorenes; Hydroxyacetylaminofluorene; Mutagenicity Tests; Ovary; Oxidation-Reduction; Paraoxon | 1988 |
Relationship between the covalent binding of N-acetoxy-2-acetylaminofluorene to DNA and a steroidal esterase activity in human mononuclear leukocytes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Beclomethasone; Carboxylic Ester Hydrolases; DNA; Female; Hot Temperature; Humans; Kinetics; Leukocytes, Mononuclear; Menstrual Cycle; Paraoxon; Sterol Esterase | 1988 |
Processing of 2-aminofluorene and 2-acetylaminofluorene DNA adducts in Chinese hamster ovary cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cells, Cultured; Cricetinae; DNA; DNA Damage; DNA Repair; Fluorenes; Hypoxanthine Phosphoribosyltransferase; Transfection | 1988 |
Interaction of the synthetic ultimate carcinogens, N-sulfonoxy- and N-acetoxy-2-acetylaminofluorene, and of enzymatically activated N-hydroxy-2-acetylaminofluorene with nucleophiles.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Biotransformation; Chemical Phenomena; Chemistry; Guanosine; Hydroxyacetylaminofluorene; Male; Methionine; Mutagenicity Tests; Mutation; Poly G; Rats; RNA, Transfer; Salmonella typhimurium | 1986 |
Specificity of N-acetoxy-N-2-acetylaminofluorene-induced frameshift mutation spectrum in mismatch repair deficient Escherichia coli strains mutH, L, S and U.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; DNA, Bacterial; Escherichia coli; Mutation; Ultraviolet Rays | 1986 |
The 32P-post-labeling method in quantitative DNA adduct dosimetry of 2-acetylaminofluorene-induced mutagenicity in Chinese hamster ovary cells and Salmonella typhimurium TA1538.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cells, Cultured; Cricetinae; Deoxyguanosine; DNA; Dose-Response Relationship, Drug; Fluorenes; Mutagenicity Tests; Phosphorus Radioisotopes; Salmonella typhimurium | 1987 |
Mutagenicity-enhancing effect of quercetin on the active metabolites of 2-acetylaminofluorene with mammalian metabolic activation systems.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Acetylation; Animals; Biotransformation; Cytosol; Drug Synergism; Flavonoids; Fluorenes; Hydroxyacetylaminofluorene; Hydroxylation; Inactivation, Metabolic; Male; Microsomes, Liver; Mutagenicity Tests; Quercetin; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1987 |
An ELISA for detection of DNA-bound carcinogen using a monoclonal antibody to N-acetoxy-2-acetylaminofluorene-modified DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Binding, Competitive; Carcinogens; DNA; Enzyme-Linked Immunosorbent Assay; Hydrolysis; Mice; Trifluoroacetic Acid | 1987 |
Metabolism of the carcinogenic air pollutant 2-nitrofluorene in the rat.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Air Pollutants; Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens, Environmental; Drug Stability; Fluorenes; Male; Mass Spectrometry; Mutagens; Rats; Rats, Inbred Strains | 1987 |
Comparison of the reactivity of B-DNA and Z-DNA with two isosteric chemical carcinogens: 2-N,N-acetoxyacetylaminofluorene and 3-N,N-acetoxyacetylamino-4,6-dimethyldipyrido-[1,2-a:3',2' -d] imidazole.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Carcinogens; DNA; Imidazoles; Kinetics; Nucleic Acid Conformation; Polydeoxyribonucleotides; Structure-Activity Relationship | 1987 |
Modulation of the embryotoxicity in vitro of reactive metabolites of 2-acetylaminofluorene by reduced glutathione and ascorbate and via sulfation.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Ascorbic Acid; Drug Interactions; Embryo, Mammalian; Female; Glutathione; In Vitro Techniques; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1986 |
Activation of N-acetoxy- and N-hydroxy-2-acetylaminofluorene to mutagenic and cytotoxic metabolites by V79 Chinese hamster cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Biotransformation; Cell Line; Cricetinae; Cricetulus; Hydroxyacetylaminofluorene; Mutagenicity Tests; Mutagens; Paraoxon; Salmonella typhimurium | 1985 |
Detection of DNA adducts in N-acetoxy-2-acetylaminofluorene-treated human fibroblasts by means of immunofluorescence microscopy and quantitative immunoautoradiography.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Autoradiography; Cell Survival; DNA; Fibroblasts; Fluorescent Antibody Technique; Humans; Immune Sera; Iodine Radioisotopes; Kinetics; Staphylococcal Protein A | 1985 |
Formation of DNA adducts from N-acetoxy-2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene in rat hemopoietic tissues in vivo.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Bone Marrow; DNA; Fluorouracil; Hematopoietic Stem Cells; Hydroxyacetylaminofluorene; Kidney; Liver; Male; Rats; Rats, Inbred F344; Spleen | 1986 |
Interaction of nucleophiles with the enzymatically-activated carcinogen, N-hydroxy-2-acetylaminofluorene, and with the model ester, N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Biotransformation; Chromatography, High Pressure Liquid; Hydroxyacetylaminofluorene; Male; Methionine; Oxidation-Reduction; Poly G; Rats; Rats, Inbred Strains; RNA, Transfer | 1985 |
Covalent binding of a carcinogen as a probe for the dynamics of deoxyribonucleic acid.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cattle; Deoxyguanosine; DNA; Hydroxyacetylaminofluorene; Kinetics; Mathematics; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Spectrophotometry; Stereoisomerism; Temperature | 1985 |
N-acetoxy-2-acetylaminofluorene modification of a deoxyoligonucleotide duplex.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chemical Phenomena; Chemistry; Circular Dichroism; Ethidium; Guanine; Hot Temperature; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligonucleotides | 1985 |
Association between DNA strand breaks and specific DNA adducts in murine hepatocytes following in vivo and in vitro exposure to N-hydroxy-2-acetylaminofluorene and N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; DNA; Dose-Response Relationship, Drug; Hydrolysis; Hydroxyacetylaminofluorene; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Paraoxon; Rats; Rats, Inbred F344 | 1985 |
Synthesis, modification with N-acetoxy-2-acetylaminofluorene and physicochemical studies of DNA model compound d(TACGTA).
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Circular Dichroism; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectrophotometry, Ultraviolet; Temperature | 1985 |
Monoclonal antibodies to DNA modified by the carcinogen N-acetoxy-N-2 acetyl aminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Antibodies, Monoclonal; Antibody Specificity; Carcinogens; DNA; Epitopes; Mice | 1984 |
C-alkylation of N-acetoxy-N-2-acetylaminofluorene: effects on its reaction with DNA in vitro.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Alkylation; DNA; Guanosine Monophosphate; Structure-Activity Relationship | 1984 |
Enhanced replication of damaged SV40 DNA in carcinogen-treated monkey cells.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cell Line; Chlorocebus aethiops; DNA Replication; Kidney; Simian virus 40; Ultraviolet Rays | 1984 |
Mutagenic, cytotoxic, and teratogenic effects of 2-acetylaminofluorene and reactive metabolites in vitro.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Acetoxyacetylaminofluorene; Animals; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Female; In Vitro Techniques; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Nitroso Compounds; Oxygenases; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1984 |
2-Acetylaminofluorene-modified probes for the indirect hybridocytochemical detection of specific nucleic acid sequences.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Sequence; Chromosomes; Crithidia; Cytomegalovirus; DNA; DNA, Satellite; DNA, Single-Stranded; Humans; Lung; Mice; Nucleic Acid Hybridization; RNA; RNA, Viral | 1984 |
Site specific cleavage of phi X-174 replicative form DNA after modification by N-acetoxy-N-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacteriophage phi X 174; Base Sequence; DNA Replication; DNA, Viral; Escherichia coli; Nucleic Acid Conformation | 1983 |
Effects of adduct formation on the biological activity of single- and double-stranded øX174 DNA, modified by N-acetoxy-N-acetyl-2-aminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Apurinic Acid; Bacteriophage phi X 174; Chemical Phenomena; Chemistry; DNA, Single-Stranded; DNA, Viral; Virus Replication | 1984 |
N-Acetoxy-acetylaminofluorene reacts preferentially with a control region of intracellular SV40 chromosome.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chromatin; Chromosome Mapping; DNA Replication; DNA, Viral; Genes, Viral; Simian virus 40; Virus Replication | 1981 |
A comparison of herpes simplex virus plaque development after viral treatment with anti-DNA or antilipid agents.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Acridines; Butylated Hydroxytoluene; DNA Replication; Dose-Response Relationship, Radiation; Ether; Simplexvirus; Ultraviolet Rays; Viral Plaque Assay; Virus Replication | 1980 |
Quantification of adducts formed in DNA treated with N-acetoxy-2-acetylaminofluorene or N-hydroxy-2-aminofluorene: comparison of trifluoroacetic acid and enzymatic degradation.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacteriophage phi X 174; Chromatography, High Pressure Liquid; DNA, Viral; Fluorenes; Mutagens; Phosphoric Monoester Hydrolases; Tritium | 1983 |
Unscheduled DNA synthesis induced by N-acetoxy-2-acetylaminofluorene is not sensitive to regulation by ADP-ribosyl transferase.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; DNA; DNA Repair; Ethylene Oxide; Gamma Rays; Humans; Hydroxyurea; In Vitro Techniques; Kinetics; Monocytes; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases | 1983 |
Hybridocytochemistry with 2-acetylaminofluorene-modified probes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; Cytomegalovirus; Fluorescent Dyes; Histocytochemistry; RNA, Viral | 1984 |
Characterization of a quantitative assay for the in vitro transformation of normal human diploid fibroblasts to anchorage independence by chemical carcinogens.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Cell Adhesion; Cell Count; Cell Division; Cells, Cultured; Culture Media; Cytological Techniques; Diploidy; Dose-Response Relationship, Drug; Fibroblasts; Humans; Infant, Newborn; Male; Phenotype; Skin | 1983 |
Analysis at the sequence level of mutations induced by the ultimate carcinogen N-acetoxy-N-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Ampicillin; Base Sequence; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Mutagenicity Tests; Mutagens; Penicillin Resistance; Tetracyclines | 1983 |
Evidence that N-acetoxy-N-acetyl-2-aminofluorene crosslinks DNA to protein by a free radical mechanism.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Ammonium Sulfate; Biphenyl Compounds; Chromatography, Ion Exchange; Cross-Linking Reagents; DNA; DNA, Bacterial; Escherichia coli; Free Radicals; Hydrazines; Muramidase; Nitrobenzenes; Picrates; Plasmids | 1983 |
Different levels of induction of RecA protein in E. coli (PQ 10) after treatment with two related carcinogens.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacterial Proteins; Carcinogens; DNA, Bacterial; Escherichia coli; Fluorenes; Kinetics; Rec A Recombinases; Ultraviolet Rays | 1983 |
Stimulation of recombination between homologous sequences on plasmid DNA and chromosomal DNA in Escherichia coli by N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; DNA Repair; DNA, Bacterial; Escherichia coli; Mutation; Plasmids; Rec A Recombinases; Recombination, Genetic | 1984 |
pBR322 plasmid DNA modified with 2-acetylaminofluorene derivatives: transforming activity and in vitro strand cleavage by the Escherichia coli uvrABC endonuclease.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; DNA Repair; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Fluorenes; Mutation; Plasmids; Substrate Specificity; Transformation, Bacterial | 1984 |
Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli. Strain specificity and mutation-prone sequences.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; DNA Repair; DNA, Bacterial; Escherichia coli; Mutation; Plasmids; Repetitive Sequences, Nucleic Acid; Species Specificity; Ultraviolet Rays | 1984 |
Termination of vitro DNA synthesis at AAF adducts in the DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacteriophage phi X 174; DNA Polymerase I; DNA Polymerase III; DNA Replication; DNA, Viral; Escherichia coli; Kinetics; Nucleic Acid Synthesis Inhibitors; Templates, Genetic | 1980 |
Sister-chromatid exchanges in human lymphocytes after a non-S-phase incubation period to allow excision DNA repair-in vitro exposure to N-acetoxy-2-acetylaminofluorene and ethylene oxide.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; DNA Repair; DNA Replication; Ethylene Oxide; Female; Humans; Interphase; Lymphocytes; Male; Sister Chromatid Exchange | 1984 |
13C- and 31P-NMR studies of the conformation of carcinogen-modified nucleic acid dimers.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Structure-Activity Relationship | 1984 |
Enhancement of the mutagenicity of carcinogenic arylamines by ethinyl estradiol.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Biotransformation; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Drug Synergism; Ethinyl Estradiol; Fluorenes; Hydroxyacetylaminofluorene; Male; Mammary Neoplasms, Experimental; Mestranol; Mutagens; Rats; Rats, Inbred Strains | 1984 |
A twin study of sister chromatid exchanges in human lymphocytes following carcinogen exposure and DNA repair incubation.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Adult; Cells, Cultured; DNA Repair; Female; Humans; Lymphocytes; Male; Pregnancy; Sister Chromatid Exchange; Time Factors; Twins; Twins, Dizygotic; Twins, Monozygotic | 1984 |
The effects of smoking, hypertension and cardiovascular disease on the estimation of unscheduled DNA synthesis and covalent binding to DNA induced by N-acetoxy-2-acetylaminofluorene in resting human mononuclear leukocytes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Aged; Cell Cycle; DNA; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Monocytes; Mutagenicity Tests; Myocardial Infarction; Risk; Smoking | 1983 |
Spectroscopic study of the effects of C-alkylation of N-acetoxy-N-acetyl-2-aminofluorene on some properties of the carcinogen-modified DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Circular Dichroism; DNA; Hot Temperature; Nucleic Acid Denaturation; Structure-Activity Relationship | 1983 |
Aberrant de novo methylation of DNA after treatment of murine cells with N-acetoxy-N-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Composition; Cell Line; Clone Cells; DNA Replication; DNA, Neoplasm; Kinetics; Methylation; Mice; Mice, Inbred Strains; Molecular Weight; Plasmacytoma | 1983 |
A genetic component of the variance of N-acetoxy-2-acetylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Adult; Blood Pressure; DNA; DNA Replication; Female; Genetic Variation; Humans; Leukocytes; Male; Pregnancy; Smoking; Twins; Twins, Dizygotic; Twins, Monozygotic | 1983 |
Preferential reaction of the carcinogen N-acetoxy-2-acetylaminofluorene with satellite DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Composition; Carcinogens; Cattle; Dactinomycin; DNA, Satellite; Fluorenes; Hot Temperature; Nucleic Acid Denaturation | 1984 |
The genotoxicity of aromatic amines in primary hepatocytes isolated from C57BL/6 and DBA/2 mice.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Biotransformation; Carcinogens; DNA; Fluorenes; Hydroxyacetylaminofluorene; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Structure-Activity Relationship | 1984 |
Interactions of caffeine and phenobarbital on sister chromatid exchanges in rat liver epithelial cell lines treated with 2-acetyl-aminofluorene and N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Caffeine; Cell Line; Cells, Cultured; Crossing Over, Genetic; Epithelial Cells; Epithelium; Liver; Metaphase; Phenobarbital; Rats; Sister Chromatid Exchange | 1984 |
DNA binding spectrum of the carcinogen N-acetoxy-N-2-acetylaminofluorene significantly differs from the mutation spectrum.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Autoradiography; DNA; DNA-Directed DNA Polymerase; Mutation; Plasmids; T-Phages | 1984 |
Electrophoretic mobility of PM2 DNA treated with ultimate chemical carcinogens or with ultraviolet light.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Acetoxyacetylaminofluorene; Bacteriophages; Benz(a)Anthracenes; Carcinogens; DNA, Superhelical; DNA, Viral; Electrophoresis, Agar Gel; Epoxy Compounds; Pseudomonas; Ultraviolet Rays | 1980 |
Infectivity and reconstitution of TMV RNA modified with N-acetoxy-2-acetylaminofluorene or benzol [a] pyrene 7,8-dihydrodiol 9,10 oxide.
Topics: 2-Acetylaminofluorene; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetoxyacetylaminofluorene; Benzopyrenes; Nucleic Acid Conformation; RNA, Viral; Tobacco Mosaic Virus; Viral Proteins | 1980 |
DNA repair in human fibroblasts treated with a combination of chemicals.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Acetoxyacetylaminofluorene; DNA Repair; Dose-Response Relationship, Drug; Fibroblasts; Humans; Nitroquinolines; Photolysis | 1981 |
Reconstitution of rods from tobacco mosaic virus protein and RNA modified with bulky carcinogens.
Topics: 2-Acetylaminofluorene; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetoxyacetylaminofluorene; Benzopyrenes; Carcinogens; Kinetics; RNA, Viral; Tobacco Mosaic Virus; Viral Proteins | 1982 |
Reactions of methylnitrosourea, epichlorohydrin, styrene oxide and acetoxyacetylaminofluorene with polyamino acids.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chemical Phenomena; Chemistry; Chlorohydrins; DNA; Epichlorohydrin; Epoxy Compounds; Ethers, Cyclic; Hydrogen-Ion Concentration; Kinetics; Methylation; Methylnitrosourea; Nitrosourea Compounds; Peptides; Time Factors | 1983 |
Characteristics of human diploid fibroblasts transformed in vitro by chemical carcinogens.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Calcium; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Diploidy; Fibroblasts; Humans; Infant, Newborn; Karyotyping; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Phenotype; Prostatic Neoplasms; Skin | 1983 |
Enzymatic methylation of chicken erythrocyte DNA modified by two carcinogens, 2-(N-acetoxyacetylamino) fluorene and methylnitrosourea.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Alkylation; Animals; Brain; Chickens; DNA; DNA (Cytosine-5-)-Methyltransferases; Erythrocytes; Kinetics; Methylation; Methylnitrosourea; Methyltransferases; Nitrosourea Compounds; Rats | 1983 |
The reproducibility of individual estimations in the covalent binding of N-acetoxy-2-acetylaminofluorene to DNA and in the induction of unscheduled DNA synthesis.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Adult; DNA; Female; Humans; Male; Menstruation; Middle Aged; Monocytes; Mutagenicity Tests; Smoking | 1983 |
DNA adduct formation and removal in N-acetoxy-2-acetylaminofluorene-exposed cultured cells and in organs from rats fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Biotransformation; Cells, Cultured; DNA; Fibroblasts; Humans; Kidney; Kinetics; Liver; Male; Mice; Mice, Inbred BALB C; Organ Specificity; Radioimmunoassay; Rats; Rats, Inbred Strains; Skin; Species Specificity | 1983 |
DNA-binding protein from HeLa cells that binds preferentially to supercoiled DNA damaged by ultraviolet light or N-acetoxy-N-acetyl-2-aminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Carrier Proteins; DNA-Binding Proteins; DNA, Superhelical; HeLa Cells; Humans; Kinetics; Structure-Activity Relationship; Ultraviolet Rays | 1982 |
Conformation of poly(dG-dC) . poly(dG-dC) modified by the carcinogens N-acetoxy-N-acetyl-2-aminofluorene and N-hydroxy-N-2-aminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Carcinogens; Circular Dichroism; Fluorenes; Hydroxylamines; Nucleic Acid Conformation; Polydeoxyribonucleotides; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1980 |
Hot spots of frameshift mutations induced by the ultimate carcinogen N-acetoxy-N-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; Chromosome Deletion; DNA Replication; DNA, Bacterial; Escherichia coli; Guanine; Mutation | 1981 |
Non-random binding of N-acetoxy-N-2-acetylamino-fluorene to chromatin subunits as visualized by immunoelectron microscopy.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Binding Sites; Chickens; Chromatin; Erythrocytes; Immunologic Techniques; Macromolecular Substances; Microscopy, Electron | 1982 |
Repair and mutagenesis of plasmid DNA modified by ultraviolet irradiation or N-acetoxy-N-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; DNA Repair; Escherichia coli; Kinetics; Mutation; Plasmids; Transformation, Bacterial; Ultraviolet Rays | 1982 |
The influence of monocyte (adherent cell) content in human mononuclear blood cell populations on the estimation of individual levels of N-acetoxy-2-acetylaminofluorene induced unscheduled DNA synthesis.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Cell Fractionation; DNA; DNA Repair; Humans; Individuality; Monocytes | 1982 |
Rapid release of carcinogen-guanine adducts from DNA after reaction with N-acetoxy-2-acetylaminofluorene or N-benzoyloxy-N-methyl-4-aminoazobenzene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Azo Compounds; Carbon Radioisotopes; Carcinogens; DNA; p-Aminoazobenzene | 1982 |
Reevaluation of a DNA binding activity with specificity for chemically modified DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Binding, Competitive; Carrier Proteins; DNA; Tritium | 1982 |
Reactivity of B and Z-DNA towards N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chemical Phenomena; Chemistry; Kinetics; Nucleic Acid Conformation; Polydeoxyribonucleotides; Structure-Activity Relationship | 1982 |
Binding of a tryptophan-containing peptide (lysyltryptophyllysine) to deoxyribonucleic acid modified by 2-(N-acetoxyacetylamino)fluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cattle; DNA; Kinetics; Mathematics; Oligopeptides; Protein Binding; Spectrometry, Fluorescence; Thymus Gland; Tryptophan | 1980 |
Conformational changes of poly(dG-dC) . poly(dG-dC) modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chemical Phenomena; Chemistry; Circular Dichroism; Molecular Conformation; Osmolar Concentration; Polydeoxyribonucleotides | 1981 |
Mechanism of reaction of carcinogen N-acetoxy-2-acetylaminofluorene with DNA.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chemical Phenomena; Chemistry; DNA; Free Radicals; Kinetics; Spin Labels; Structure-Activity Relationship; Tritium | 1981 |
A novel method for the small scale synthesis of N-acetoxy-2-acetylaminofluorene and its adducts.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Nucleosides; Nucleotides | 1981 |
Starvation for arginine and glutamine sensitizes human diploid cells to the transforming effects of N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Arginine; Cell Transformation, Neoplastic; Cells, Cultured; DNA Repair; DNA Replication; Fibroblasts; Glutamine; Humans; Kinetics; Male; Skin; Skin Physiological Phenomena | 1981 |
Determinants of nucleic acid adduct formation.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Biotransformation; Calorimetry; Carcinogens; DNA; Molecular Conformation; Stilbenes; Structure-Activity Relationship; Xanthines | 1981 |
Modification of PM2 DNA with N-acetoxy-2-acetylaminofluorene: changes in buoyant density, electrophoretic mobility and electron microscopic structure.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacteriophages; Centrifugation; DNA, Superhelical; DNA, Viral; Electrophoresis, Agar Gel; Microscopy, Electron; Pseudomonas | 1980 |
Characterization of collagen synthesized by normal and chemically transformed rat liver epithelial cell lines.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cell Line; Cell Transformation, Neoplastic; Collagen; Epithelium; Liver; Peptide Fragments; Rats | 1980 |
Decreased fidelity in one subspecies of DNA polymerase-alpha that appears during N-2-acetylaminofluorene hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; DNA Polymerase II; DNA-Directed DNA Polymerase; Isoenzymes; Liver; Male; Poly dA-dT; Rats | 1980 |
Modulation by caffeine of enhanced postreplication repair in mammalian cells treated with N-acetoxy-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Caffeine; Cell Line; Cricetinae; DNA Repair; DNA Replication; Humans | 1980 |
Repair of damage by N-acetoxy-2-acetylaminofluorene in Bloom's syndrome.
Topics: 2-Acetylaminofluorene; Abnormalities, Multiple; Acetoxyacetylaminofluorene; Cells, Cultured; DNA; DNA Repair; Fibroblasts; Hydrolysis; Molecular Weight | 1980 |
Effect of culture conditions, cell type, and species of origin on the distribution of acetylated and deacetylated deoxyguanosine C-8 adducts of N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Acetylation; Animals; Cells, Cultured; Dealkylation; Deoxyguanosine; DNA; Epidermis; Liver; Mice; Paraoxon; Rats; Species Specificity | 1980 |
Direct comparison, in humans resting lymphocytes, of the inter-individual variations in unscheduled DNA synthesis induced by N-acetoxy-2-acetylaminofluorene and ultraviolet irradiation.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Chromosomes; DNA; DNA Repair; DNA Replication; Humans; Leukocytes; Mutation; Ultraviolet Rays | 1980 |
Excision of N-acetoxy-2-acetylaminofluorene-induced DNA adducts from chromatin fractions of human fibroblasts.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Cells, Cultured; Chromatin; DNA; DNA Repair; Fibroblasts; Humans; Nucleosomes; Xeroderma Pigmentosum | 1980 |
Preferential promutagenic lesions at exons 7-8 of human p53 genomic DNA induced by the direct-acting hepatocarcinogens N-nitroso-2-acetylaminofluorene and N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; DNA Adducts; DNA Primers; Dose-Response Relationship, Drug; Exons; Genes, p53; Humans; In Vitro Techniques; Molecular Sequence Data; Mutation; Nitroso Compounds; Plasmids | 1995 |
DNA-damaging effects of genotoxins in mixture: nonadditive effects of aflatoxin B1 and N-acetylaminofluorene on their mutagenicity in Salmonella typhimurium.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Aflatoxin B1; Alleles; DNA Damage; Frameshift Mutation; Mutagenicity Tests; Mutagens; Salmonella typhimurium | 1999 |
Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line; Drug Resistance, Multiple; Electrophoretic Mobility Shift Assay; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Kinase; NADPH Oxidases; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rac GTP-Binding Proteins; RNA, Messenger; Signal Transduction; Superoxides; Tumor Cells, Cultured; Up-Regulation | 2002 |
GenoMass--a computer software for automated identification of oligonucleotide DNA adducts from LC-MS analysis of DNA digests.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Alkaline Phosphatase; Base Sequence; Chromatography, High Pressure Liquid; DNA; Endodeoxyribonucleases; Endoribonucleases; Mass Spectrometry; Molecular Sequence Data; Oligonucleotides; Software | 2009 |