2-acetylaminofluorene has been researched along with acetaminophen in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Nebert, DW; Thorgeirsson, SS | 1 |
| Grantham, PH; Idoine, JB; Mohan, LC; Weisburger, EK; Weisburger, JH | 1 |
| Felton, JS; Nebert, DW; Thorgeirsson, SS | 1 |
| Hasegawa, R; Imaida, K; Ito, N; Shirai, T; Takahashi, S; Yamaguchi, S | 1 |
| Holmes, EH | 1 |
| Harris, C; Juchau, MR; Luchtel, DL; Stark, KL | 1 |
| Harris, C; Juchau, MR; Stark, KL | 2 |
| Inoue, K; Ito, N; Masui, T; Ogiso, T; Tsuda, H | 1 |
| Cassady, JM; DeFrees, SA; Elliott, WL; Heinstein, PF; Morré, DJ; Sawick, DP | 1 |
| Gillette, JR; Hinson, JA; Pohl, LR | 1 |
| Lin, JK; Lin-Shiau, SY; Wang, JM | 1 |
| Duan, JD; Iatropoulos, MJ; Jeffrey, AM; Perrone, CE; Williams, GM | 1 |
| Ando, Y; Kiyosawa, N; Manabe, S; Niino, N; Watanabe, K; Yamoto, T | 1 |
1 review(s) available for 2-acetylaminofluorene and acetaminophen
| Article | Year |
|---|---|
The Ah locus and the metabolism of chemical carcinogens and other foreign compounds.
Topics: 2-Acetylaminofluorene; Acetaminophen; Alleles; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Carcinogens; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; Genes; Humans; Liver; Lymphocytes; Mice; Mice, Inbred Strains; Mutagens; NADPH-Ferrihemoprotein Reductase; Neoplasms, Experimental; Oxygenases; Polycyclic Compounds; Salmonella; Species Specificity | 1977 |
14 other study(ies) available for 2-acetylaminofluorene and acetaminophen
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Mechanisms of the inhibitory action of p-hydroxyacetanilide on carcinogenesis by N-2-fluorenylacetamide or N-hydroxy-N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Acetaminophen; Amidohydrolases; Animals; Body Weight; Eating; Feces; Fluorenes; Glucuronates; Glucuronosyltransferase; Hydroxyacetylaminofluorene; Liver; Male; Protein Binding; Rats; Rats, Inbred F344; Sulfuric Acids | 1976 |
Genetic differences in the aromatic hydrocarbon-inducible n-hydroxylation of 2-acetylaminofluorene and acetaminophen-produced hepatotoxicity in mice.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Enzyme Induction; Fluorenes; Hydrocarbons; In Vitro Techniques; Kinetics; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Molecular Biology | 1975 |
Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rats initially treated with diethylnitrosamine.
Topics: 2-Acetylaminofluorene; Acetaminophen; Aging; Animals; Biomarkers, Tumor; Body Weight; Carcinogens; Diethylnitrosamine; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344 | 1991 |
GDP-fucose:GM1 alpha 1----2fucosyltransferase is activated in parenchymal cells of rat liver during early stages of N-2-acetylaminofluorene induced hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Biomarkers, Tumor; Carbohydrate Sequence; Enzyme Activation; Fucosyltransferases; Hexosyltransferases; Liver; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Rats; Rats, Inbred F344; Reference Values | 1990 |
Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Acetaminophen; Animals; Biological Availability; Catechols; DNA; Embryo, Mammalian; Enzyme Induction; Hydroxyacetylaminofluorene; Inactivation, Metabolic; Liver; Methylcholanthrene; Neural Tube Defects; Organ Culture Techniques; Proteins; Rats | 1989 |
Modulation of the embryotoxicity and cytotoxicity elicited by 7-hydroxy-2-acetylaminofluorene and acetaminophen via deacetylation.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Acetaminophen; Acetylation; Animals; Cell Survival; Embryo, Mammalian; Embryonal Carcinoma Stem Cells; Female; Hydroxyacetylaminofluorene; Neoplastic Stem Cells; Neural Tube Defects; Pregnancy; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1989 |
Influence of electrophilic character and glutathione depletion on chemical dysmorphogenesis in cultured rat embryos.
Topics: 2-Acetylaminofluorene; Acetaminophen; Acetoxyacetylaminofluorene; Animals; Biotransformation; Embryo, Mammalian; Fetal Proteins; Glutathione; Morphogenesis; Rats; Rats, Inbred Strains | 1989 |
Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Acetaminophen; Aniline Compounds; Animals; Body Weight; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Diethylnitrosamine; Eating; Ethoxyquin; Glutathione; Liver Neoplasms, Experimental; Male; Quinolines; Rats; Rats, Inbred F344; Vitamin E | 1986 |
Cyclic modulation of enzymes of pyrimidine nucleotide biosynthesis precedes sialoglycoconjugate changes during 2-acetylaminofluorene-induced hepatocarcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Carbon-Nitrogen Ligases; Dihydroorotate Oxidase; Ligases; Liver Neoplasms, Experimental; Liver Regeneration; Male; Nucleoside-Diphosphate Kinase; Pyrimidine Nucleotides; Rats; Rats, Inbred F344; Starvation | 1984 |
A simple high-pressure liquid chromatographic assay for the N-hydroxy derivatives of phenacetin, acetaminophen, 2-acetylaminofluorene, and other hydroxamic acids.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cricetinae; Hydroxamic Acids; Hydroxyacetylaminofluorene; Male; Mesocricetus; Microsomes, Liver; Phenacetin; Spectrophotometry; Structure-Activity Relationship | 1980 |
Relaxation of rat thoracic aorta by N-nitroso compounds and nitroprusside and their modifications of nucleic acid bases through release of nitric oxide.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Aorta, Thoracic; Deamination; Dose-Response Relationship, Drug; Female; Hemoglobins; Hydroxylation; Male; Methylene Blue; Methylnitronitrosoguanidine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Nitroso Compounds; Nucleic Acids; Rats; Rats, Wistar | 1993 |
Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Antineoplastic Agents; Body Weight; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 2007 |
Scoring multiple toxicological endpoints using a toxicogenomic database.
Topics: 2-Acetylaminofluorene; Acetaminophen; Algorithms; Animals; Biomarkers; Clofibrate; Data Interpretation, Statistical; Databases, Genetic; Endpoint Determination; Gene Expression; Liver; Male; Oligonucleotide Array Sequence Analysis; Phenobarbital; Rats; Rats, Sprague-Dawley; Toxicity Tests; Toxicogenetics | 2009 |