Page last updated: 2024-09-04

2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman and simvastatin

2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman has been researched along with simvastatin in 1 studies

Compound Research Comparison

Studies
(2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman)
Trials
(2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman)
Recent Studies (post-2010)
(2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman)
Studies
(simvastatin)
Trials
(simvastatin)
Recent Studies (post-2010) (simvastatin)
45478,4421,7303,630

Protein Interaction Comparison

ProteinTaxonomy2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman (IC50)simvastatin (IC50)
photoreceptor-specific nuclear receptorHomo sapiens (human)1.164
transactivating tegument protein VP16 [Human herpesvirus 1]Human alphaherpesvirus 1 (Herpes simplex virus type 1)4.426
Bile salt export pumpHomo sapiens (human)10
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.7843
ATP-dependent translocase ABCB1Homo sapiens (human)9.5
Insulin receptor Rattus norvegicus (Norway rat)0.0034
Prostaglandin G/H synthase 2Homo sapiens (human)0.0034
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0111
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.049
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)6.7

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cavalca, V; De Franceschi, M; Massironi, P; Tremoli, E; Veglia, F; Werba, JP; Zingaro, L1

Trials

1 trial(s) available for 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman and simvastatin

ArticleYear
A new compound-specific pleiotropic effect of statins: modification of plasma gamma-tocopherol levels.
    Atherosclerosis, 2007, Volume: 193, Issue:1

    Topics: Adult; Aged; Cholesterol, LDL; Chromans; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Female; gamma-Tocopherol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Pravastatin; Propionates; Prospective Studies; Simvastatin

2007