2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman has been researched along with d-alpha tocopherol in 29 studies
| Studies (2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman) | Trials (2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman) | Recent Studies (post-2010) (2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman) | Studies (d-alpha tocopherol) | Trials (d-alpha tocopherol) | Recent Studies (post-2010) (d-alpha tocopherol) |
|---|---|---|---|---|---|
| 45 | 4 | 7 | 32,198 | 2,903 | 7,258 |
| Protein | Taxonomy | 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman (IC50) | d-alpha tocopherol (IC50) |
|---|---|---|---|
| Glutathione S-transferase P | Homo sapiens (human) | 0.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 20 (68.97) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Bamonti, L; Böhmdorfer, S; Galli, F; Gille, L; Kelly, FJ; Mazzini, F; Netscher, T; Piroddi, M; Rosenau, T | 1 |
| Borchardt, D; Dewind, SA; Kantoci, D; Khan, SI; Murray, ED; Wechter, WJ | 1 |
| Anner, BM; Gibson, KM; Kantoci, D; Leipold, D; Murray, ED; Pham, T; Quiggle, DD; Wang, WH; Wechter, WJ | 1 |
| Ben, RN; Burton, GW; Parker, RS; Swanson, JE | 1 |
| Brigelius-Flohé, R; Graf, P; Sies, H; Stahl, W; Wechter, W | 1 |
| Abe, K; Fukushima, T; Hattori, A; Imai, K; Yoshimura, H | 1 |
| Hamamura, K; Igarashi, O; Kaneko, K; Kiyose, C; Saito, H; Tomioka, M; Ueda, T | 1 |
| Appenroth, D; Fleck, C; Karge, E; Kiessling, G; Wechter, WJ; Winnefeld, K | 1 |
| Ames, BN; Christen, S; Jiang, Q; Shigenaga, MK | 1 |
| Graf, P; Polidori, MC; Radosavac, D; Sies, H; Stahl, W | 1 |
| Hamamura, K; Morinobu, T; Tamai, H; Yoshikawa, S | 1 |
| Ames, BN; Jiang, Q | 1 |
| Igarashi, O; Kiyose, C; Kondo, K; Saito, H; Ueda, T; Yoshimura, H | 1 |
| Atkinson, J; Floridi, A; Galli, F; Kelly, FJ; Lee, R | 1 |
| Azzi, A; Betti, M; Conte, C; Floridi, A; Galli, F; Pistilli, A; Rende, M; Stabile, AM | 1 |
| Elmadfa, I; Kamal-Eldin, A; Wagner, KH | 1 |
| Hall, WL; Jeanes, YM; Lodge, JK; Proteggente, AR | 1 |
| Cross, CE; Gohil, K; Krueger, SK; Leonard, SW; Schock, B; Siddens, LK; Traber, MG; Williams, DE | 1 |
| Brigelius-Flohé, R; Ribalta, J; Rock, E; Roob, JM; Tiran, B; Winklhofer-Roob, BM; Wuga, S | 1 |
| Hamamura, K; Hirahara, F; Iwamoto, T; Morinobu, T; Tamai, H; Yoshikawa, S | 1 |
| Akaho, N; Fujioka, T; Fukui, K; Fukushima, T; Hattori, A; Hidaka, R; Imai, K; Karube, Y; Matsunaga, K; Takata, J; Yoshida, M | 1 |
| Abe, C; Ichikawa, T; Ikeda, S; Uchida, T; Yamashita, K | 1 |
| Ahn, SH; Cho, JY; Gonzalez, FJ; Idle, JR; Kang, DW; Krausz, KW; Luecke, H; Ma, X | 1 |
| Burnett, JR; Clarke, MW; Croft, KD; Hodgson, JM; Ledowski, T; Puddey, IB; Wu, JH | 1 |
| Leonard, SW; Traber, MG | 1 |
| Abe, C; Ichikawa, T; Ikeda, S; Nomura, S; Uchida, T | 1 |
| Frank, J; Graeve, L; Grebenstein, N; Schumacher, M | 1 |
| Ikeda, S; Nomura, S; Oda, H; Uchida, T | 1 |
| Boerwinkle, E; Cai, J; Chen, H; Dai, Y; Daviglus, M; Feofanova, EV; Grove, ML; Jia, P; Kaplan, RC; Laurie, CC; Morrison, AC; North, KE; Qi, Q; Yu, B | 1 |
2 review(s) available for 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman and d-alpha tocopherol
| Article | Year |
|---|---|
gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention.
Topics: Aging; alpha-Tocopherol; Animals; Antioxidants; Biological Availability; Cardiovascular Diseases; Chromans; gamma-Tocopherol; Humans; Intestinal Absorption; Neoplasms; Nutritive Value; Propionates; Prostaglandin-Endoperoxide Synthases; Vitamin E Deficiency | 2001 |
Gamma-tocopherol--an underestimated vitamin?
Topics: alpha-Tocopherol; Antioxidants; Biological Availability; Chromans; gamma-Tocopherol; Humans; Intestinal Absorption; Neoplasms; Nutritive Value; Propionates | 2004 |
2 trial(s) available for 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman and d-alpha tocopherol
| Article | Year |
|---|---|
gamma-Tocopherol biokinetics and transformation in humans.
Topics: Adult; alpha-Tocopherol; Chromans; Chromatography, High Pressure Liquid; Female; gamma-Tocopherol; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Male; Middle Aged; Propionates; Tocopherols; Vitamin E | 2003 |
Vitamin E supplementation and hepatic drug metabolism in humans.
Topics: Adult; alpha-Tocopherol; Area Under Curve; Biotransformation; Chromans; Cytochrome P-450 CYP3A; Dietary Supplements; Double-Blind Method; Drug Interactions; Female; gamma-Tocopherol; Humans; Liver; Male; Midazolam; Middle Aged; Pharmaceutical Preparations; Propionates; Vitamin E | 2009 |
25 other study(ies) available for 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman and d-alpha tocopherol
| Article | Year |
|---|---|
Tocotrienamines and tocopheramines: reactions with radicals and metal ions.
Topics: Amines; Biphenyl Compounds; Chromans; Electron Spin Resonance Spectroscopy; Ferric Compounds; Free Radical Scavengers; Kinetics; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Picrates; Vitamin E | 2011 |
Endogenous natriuretic factors 6: the stereochemistry of a natriuretic gamma-tocopherol metabolite LLU-alpha.
Topics: Chromans; Humans; Hydrolysis; Natriuresis; Propionates; Spectrum Analysis; Stereoisomerism; Vitamin E | 1997 |
Endogenous natriuretic factors 7: biospecificity of a natriuretic gamma-tocopherol metabolite LLU-alpha.
Topics: Animals; Binding Sites; Chromans; Natriuresis; Potassium Channel Blockers; Propionates; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Vitamin E | 1997 |
Urinary excretion of 2,7, 8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman is a major route of elimination of gamma-tocopherol in humans.
Topics: Adult; Chromans; Deuterium; Diet; Female; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Magnetic Resonance Spectroscopy; Male; Propionates; Vitamin E | 1999 |
Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman and 2,7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman in human serum.
Topics: Adult; Chromans; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Middle Aged; Propionates; Reproducibility of Results; Vitamin E | 1999 |
Production of LLU-alpha following an oral administration of gamma-tocotrienol or gamma-tocopherol to rats.
Topics: Animals; Antioxidants; Chromans; Chromatography, High Pressure Liquid; gamma-Tocopherol; Male; Natriuresis; Propionates; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vitamin E | 2000 |
Alpha-tocopherol affects the urinary and biliary excretion of 2,7,8-trimethyl-2 (2'-carboxyethyl)-6-hydroxychroman, gamma-tocopherol metabolite, in rats.
Topics: alpha-Tocopherol; Animals; Bile; Calibration; Chromans; Chromatography, High Pressure Liquid; Humans; Hydrolysis; Male; Mass Spectrometry; Methylation; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Vitamin E Deficiency | 2001 |
LLU-alpha, an endogenous metabolite of gamma-tocopherol, is more effective against metal nephrotoxicity in rats than gamma-tocopherol.
Topics: Animals; Antioxidants; Chromans; Chromates; Female; Kidney; Luminescent Measurements; Metals; Potassium Channels; Propionates; Rats; Rats, Wistar; Thallium; Vitamin E | 2001 |
Tocopherol metabolites 2, 5, 7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman (alpha-CEHC) and 2, 7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman (gamma-CEHC) in human serum after a single dose of natural vitamin E.
Topics: Adult; alpha-Tocopherol; Biological Availability; Chromans; Chromatography, High Pressure Liquid; Female; gamma-Tocopherol; Humans; Isomerism; Male; Propionates; Tocopherols; Vitamin E | 2002 |
Measurement of vitamin E metabolites by high-performance liquid chromatography during high-dose administration of alpha-tocopherol.
Topics: Adult; alpha-Tocopherol; Antioxidants; Area Under Curve; Chromans; Chromatography, High Pressure Liquid; Humans; Male; Propionates; Vitamin E | 2003 |
Gamma-tocopherol, but not alpha-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Carrageenan; Chromans; Dinoprostone; Dose-Response Relationship, Drug; Eating; Eicosanoids; Exudates and Transudates; gamma-Tocopherol; Inflammation; Leukotriene B4; Lipid Peroxidation; Male; Neutrophil Infiltration; Nitrates; Nitrites; Propionates; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2003 |
Gamma-tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor.
Topics: Animals; Chromans; Male; Molecular Structure; Potassium; Propionates; Rats; Rats, Sprague-Dawley; Sodium; Vitamin E; Vitamin E Deficiency | 2003 |
The effect of alpha- and gamma-tocopherol and their carboxyethyl hydroxychroman metabolites on prostate cancer cell proliferation.
Topics: alpha-Tocopherol; Antioxidants; Cell Division; Chromans; Cyclin D1; Dose-Response Relationship, Drug; gamma-Tocopherol; Humans; Male; Propionates; Prostatic Neoplasms | 2004 |
Cigarette smokers have decreased lymphocyte and platelet alpha-tocopherol levels and increased excretion of the gamma-tocopherol metabolite gamma-carboxyethyl-hydroxychroman (gamma-CEHC).
Topics: Adult; alpha-Tocopherol; Antioxidants; Ascorbic Acid; Blood Platelets; Chromans; Dinoprost; Female; Humans; Lymphocytes; Male; Middle Aged; Propionates; Smoking; Uric Acid | 2004 |
Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.
Topics: alpha-Tocopherol; Animal Feed; Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Brain; Carrier Proteins; Chromans; Cytochrome P-450 CYP3A; gamma-Tocopherol; Genotype; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidoreductases, N-Demethylating; Oxygen; Propionates; Time Factors; Vitamin E; Xenobiotics | 2005 |
The effect of age on vitamin E status, metabolism, and function: metabolism as assessed by labeled tocopherols.
Topics: Absorption; Adult; Aged; Aging; alpha-Tocopherol; Austria; Chromans; Deuterium; gamma-Tocopherol; Humans; Male; Middle Aged; Nutritional Status; Propionates; Tocopherols; Vitamin E | 2004 |
The effect of gamma-tocopherol administration on alpha-tocopherol levels and metabolism in humans.
Topics: Adult; alpha-Tocopherol; Antioxidants; Biological Availability; Chromans; Chromatography, High Pressure Liquid; gamma-Tocopherol; Humans; Male; Propionates; Sodium; Vitamin E | 2005 |
Preparation and in vivo evaluation of a water-soluble prodrug for 2R-gamma-tocotrienol and as a two-step prodrug for 2,7,8-trimethyl-2S-(beta-carboxyethyl)-6-hydroxychroman (S-gamma-CEHC) in rat.
Topics: Animals; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Chromans; Chromatography, High Pressure Liquid; Esters; Excipients; Humans; Hydrolysis; In Vitro Techniques; Microsomes, Liver; Palm Oil; Pharmaceutical Solutions; Physostigmine; Plant Oils; Prodrugs; Propionates; Rats; Solubility; Spectrophotometry, Ultraviolet; Surface-Active Agents; Tissue Distribution; Vitamin E | 2007 |
Dietary sesame seed decreases urinary excretion of alpha- and gamma-tocopherol metabolites in rats.
Topics: alpha-Tocopherol; Animals; Chromans; gamma-Tocopherol; Kidney; Liver; Lung; Male; Propionates; Rats; Rats, Wistar; Seeds; Sesamum | 2007 |
Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.
Topics: Animals; Chromans; Gene Expression; Humans; Liver; Male; Mass Spectrometry; Metabolomics; Mice; Mice, Knockout; Molecular Structure; Oxidation-Reduction; Pregnane X Receptor; Pregnenolone Carbonitrile; Propionates; Receptors, Steroid; Urine; Vitamin E; Vitamins | 2009 |
Measurement of the vitamin E metabolites, carboxyethyl hydroxychromans (CEHCs), in biological samples.
Topics: Animals; Chromans; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Propionates; Vitamin E | 2006 |
Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol.
Topics: 14-alpha Demethylase Inhibitors; Administration, Oral; alpha-Tocopherol; Animals; Biological Transport; Chromans; gamma-Tocopherol; Intestine, Small; Kidney; Liver; Male; Organ Specificity; Propionates; Rats; Rats, Wistar; Tocotrienols; Vitamin E | 2011 |
α-Tocopherol transfer protein is not required for the discrimination against γ-tocopherol in vivo but protects it from side-chain degradation in vitro.
Topics: alpha-Tocopherol; Animals; Carrier Proteins; Chromans; Dioxoles; Female; gamma-Tocopherol; Hep G2 Cells; Humans; Lignans; Liver; Mice; Mice, Knockout; Mixed Function Oxygenases; Oxidation-Reduction; Propionates | 2014 |
γ-Tocopherol Is Metabolized Faster than α-Tocopherol in Young Japanese Women.
Topics: Adult; alpha-Tocopherol; Chromans; Chromatography, High Pressure Liquid; Diet; Eating; Female; gamma-Tocopherol; Humans; Japan; Nutritional Status; Propionates; Young Adult | 2018 |
A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos.
Topics: Adult; Chromans; Cohort Studies; Coronary Disease; Cytochrome P450 Family 4; Diabetes Mellitus, Type 2; Female; Gene Expression; Genetic Predisposition to Disease; Genome-Wide Association Study; Genome, Human; Hispanic or Latino; Humans; Male; Membrane Transport Proteins; Metabolome; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Propionates; Public Health; Quantitative Trait Loci; Quantitative Trait, Heritable; Vitamin E | 2020 |