Page last updated: 2024-08-17

2,6-diisocyanatotoluene and toluene 2,4-diisocyanate

2,6-diisocyanatotoluene has been researched along with toluene 2,4-diisocyanate in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (35.90)	18.7374
1990's	14 (35.90)	18.2507
2000's	8 (20.51)	29.6817
2010's	3 (7.69)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baj, A; Nano, G; Sesana, G	1
Allegra, L; Calabrò, F; Fasoli, A; Mattoli, S; Mezzetti, M; Miante, S	1
Chitano, P; Fabbri, LM; Geppetti, P; Maggi, CA; Mapp, CE; Patacchini, R; Santicioli, P	1
Casciano, DA; Robinson, BY; Shaddock, JG	1
Brorson, T; Renman, L; Sangö, C; Skarping, G	1
Botham, PA; Hext, PM; Rattray, NJ; Walsh, ST; Woodcock, DR	1
Fabbri, LM	1
Hammad, YY; Rando, RJ	1
Ito, T; Kudo, T; Miki, T; Shima, S; Tachikawa, S; Yoshida, T	1
Ahti, J; Assmuth, T; Haahtela, T; Kurvonen, E; Nieminen, T; Nuorteva, P; Saarainen, T; Seppälä, K; Veide, P; Viholainen, S	1
Abdel-Kader, H; Duvoisin, PF; Hammad, YY; Rando, RJ	1
Abdel-Kader, H; Hammad, YY; Hughes, J; Rando, RJ	1
Dolovich, J; Grammer, LC; Hargreave, FE; Harris, KE; Patterson, R	1
Filieri, M; Gerosa, F; Paggiaro, P; Pezzini, A; Riviera, A; Spiazzi, A; Toma, G; Tridente, G	1
Baschieri, L; Ferrante, B; Loi, AM; Paggiaro, PL; Pardi, F; Roselli, MG; Rossi, O	1
Ebell, GF; Fleming, DE; Genovese, JH; Taylor, GA	1
Loeser, E	1
Huff, JE	1
Okamoto, Y; Sawahata, T; Sugawara, Y; Tanaka, K	1
Aoyama, K; Huang, J; Ueda, A	1
Calcagni, PG; Di Stefano, A; Fabbri, LM; Hosselet, JJ; Maestrelli, P; Mapp, CE; Saetta, M; Santonastaso, A	1
Dalene, M; Lind, P; Skarping, G	1
Benoit, FM	1
Berode, M; Maître, A; Perdrix, A; Romazini, S; Savolainen, H	1
Dalene, M; Hagmar, L; Lind, P; Skarping, G	1
Boukortt, S; Buchet, JP; Carbonnelle, P; Lison, D	1
Basalyga, DM; Day, BW; Jin, R; Karol, MH; Kramarik, JA	1
Dalene, M; Grubb, A; Lind, P; Lindström, V; Skarping, G	1
Halliburton, AT; Shiotsuka, RN; Sturdivant, DW; Warren, DL	1
Hirvonen, A; Kääriä, K; Norppa, H; Piirilä, P; Rosenberg, C; Vainio, H	1
Kim, Y; Morita, Y; Sakai, T; Tao, YX	1
Karol, MH; Lange, RW; Lemus, R; Luster, MI; Matheson, JM	1
Gagné, S; Lesage, J; Ostiguy, C; Van Tra, H	1
Cloutier, Y; Gagne, S; Lesage, J; Ostiguy, C; Van Tra, H	1
Chang, HY; Lin, WC; Shih, TS; Tsai, PJ; Wang, ST; Yeh, HJ	1
Maklakov, LI; Suchkova, GG	1
Axmon, A; Broberg, KE; Jönsson, BA; Littorin, M; Rannug, A; Sennbro, CJ; Tinnerberg, H; Warholm, M	1
Hettick, JM; Siegel, PD	1
Asaoka, Y; Kitsukawa, M; Maeda, A; Miyamoto, Y; Miyoshi, T; Mutsuga, M; Nakajima, M; Oshida, K; Takahashi, K; Tsuchiyama, H	1

Reviews

1 review(s) available for 2,6-diisocyanatotoluene and toluene 2,4-diisocyanate

Article	Year
Airway inflammation and asthma. Importance of arachidonate metabolites for airway hyperresponsiveness. Progress in biochemical pharmacology, 1985, Volume: 20 Topics: Acetylcholine; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Humans; Inflammation; Ozone; Prednisone; Time Factors; Toluene 2,4-Diisocyanate	1985

Trials

1 trial(s) available for 2,6-diisocyanatotoluene and toluene 2,4-diisocyanate

Article	Year
Determination of toluenediamines in urine of workers occupationally exposed to isocyanates by high-performance liquid chromatography. The Analyst, 1996, Volume: 121, Issue:5 Topics: Chromatography, High Pressure Liquid; Humans; Isocyanates; Isomerism; Occupational Exposure; Toluene 2,4-Diisocyanate	1996

Other Studies

37 other study(ies) available for 2,6-diisocyanatotoluene and toluene 2,4-diisocyanate

Article	Year
A new tool for sampling airborne isocyanates. American Industrial Hygiene Association journal, 1991, Volume: 52, Issue:5 Topics: Air Pollutants; Aniline Compounds; Chemistry Techniques, Analytical; Cyanates; Isocyanates; Toluene 2,4-Diisocyanate	1991
Bronchial epithelial cells exposed to isocyanates potentiate activation and proliferation of T-cells. The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 1 Topics: Alkaline Phosphatase; Bronchi; Cell Adhesion; Cell Survival; Cells, Cultured; Epithelial Cells; Epithelium; HLA-DR Antigens; Humans; Immunohistochemistry; Isomerism; Keratins; Lymphocyte Activation; Mucous Membrane; Receptors, Interleukin-2; T-Lymphocytes; Toluene 2,4-Diisocyanate	1990
Evidence that toluene diisocyanate activates the efferent function of capsaicin-sensitive primary afferents. European journal of pharmacology, 1990, May-03, Volume: 180, Issue:1 Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyanates; Electric Stimulation; Ganglia, Autonomic; In Vitro Techniques; Male; Muscle Denervation; Neurons, Efferent; Rats; Rats, Inbred Strains; Toluene 2,4-Diisocyanate; Urinary Bladder	1990
Effect of pretreatment with hepatic mixed-function oxidase inducers on the genotoxicity of four rat carcinogens in the hepatocyte/DNA repair assay. Mutagenesis, 1990, Volume: 5, Issue:4 Topics: Acrylates; Animals; Aroclors; Carcinogens; Cells, Cultured; DNA Repair; Dose-Response Relationship, Drug; Isomerism; Liver; Male; Methylcholanthrene; Mutagenicity Tests; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphites; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Toluene 2,4-Diisocyanate; Ziram	1990
Test atmospheres of diisocyanates with special reference to controlled exposure of humans. International archives of occupational and environmental health, 1989, Volume: 61, Issue:8 Topics: Air Pollutants; Atmosphere Exposure Chambers; Cyanates; Environmental Monitoring; Equipment Design; Humans; Isocyanates; Male; Toluene 2,4-Diisocyanate	1989
Sensitisation of guinea pigs by inhalation exposure to low molecular weight chemicals. Toxicology letters, 1988, Volume: 41, Issue:2 Topics: Allergens; Animals; Cyanates; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; Lung; Passive Cutaneous Anaphylaxis; Phthalic Acids; Phthalic Anhydrides; Respiration; Toluene 2,4-Diisocyanate; Triazines	1988
Modified Marcali method for the determination of total toluenediisocyanate in air. American Industrial Hygiene Association journal, 1985, Volume: 46, Issue:4 Topics: Air Pollutants, Occupational; Chemical Phenomena; Chemistry; Cyanates; Isomerism; Spectrophotometry; Toluene 2,4-Diisocyanate	1985
[Health hazards in workers of small scale polyurethane production factory]. Sangyo igaku. Japanese journal of industrial health, 1986, Volume: 28, Issue:2 Topics: Adolescent; Adult; Aged; Asthma; Chemical Industry; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Morbidity; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate	1986
The prevalence of asthma among inhabitants in the vicinity of a polyurethane factory in Finland. Environmental research, 1987, Volume: 43, Issue:2 Topics: Adolescent; Adult; Air Pollutants, Occupational; Asthma; Child; Environmental Exposure; Finland; Humans; Isomerism; Middle Aged; Polyurethanes; Sulfur Dioxide; Toluene 2,4-Diisocyanate	1987
A sequential tape monitor for toluene diisocyanate. American Industrial Hygiene Association journal, 1987, Volume: 48, Issue:6 Topics: Air Pollutants, Occupational; Cyanates; Industry; Polyurethanes; Toluene 2,4-Diisocyanate	1987
Toluene diisocyanate exposures in the flexible polyurethane foam industry. American Industrial Hygiene Association journal, 1987, Volume: 48, Issue:6 Topics: Air Pollutants, Occupational; Chemical Industry; Chromatography, High Pressure Liquid; Cyanates; Humans; Maximum Allowable Concentration; Polyurethanes; Toluene 2,4-Diisocyanate	1987
Toluene diisocyanate respiratory reactions. I. Reassessment of the problem. International archives of allergy and applied immunology, 1987, Volume: 84, Issue:1 Topics: Adult; Asthma; Cyanates; Humans; Immunoglobulins; Isomerism; Middle Aged; Occupational Diseases; Respiration; Toluene 2,4-Diisocyanate	1987
Specific IgE antibodies in twenty-eight workers with diisocyanate-induced bronchial asthma. Clinical allergy, 1984, Volume: 14, Issue:5 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Toluene 2,4-Diisocyanate	1984
Follow-up study of patients with respiratory disease due to toluene diisocyanate (TDI). Clinical allergy, 1984, Volume: 14, Issue:5 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate	1984
Simultaneous determination of 2,4- and 2,6-diisocyanatotoluene (TDI) and 3,3'-dichloro-4,4'-diaminodiphenylmethane (MOCA) in air. The Annals of occupational hygiene, 1980, Volume: 23, Issue:2 Topics: Air; Benzhydryl Compounds; Cyanates; Methylenebis(chloroaniline); Toluene 2,4-Diisocyanate	1980
Long-term toxicity and carcinogenicity studies with 2,4/2,6-toluene-diisocyanate (80/20) in rats and mice. Toxicology letters, 1983, Volume: 15, Issue:1 Topics: Animals; Carcinogens; Cell Nucleus; Cyanates; Female; Gases; Isomerism; Male; Mice; Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity; Toluene 2,4-Diisocyanate	1983
Carcinogenesis results on seven amines, two phenols, and one diisocyanate used in plastics and synthetic elastomers. Progress in clinical and biological research, 1984, Volume: 141 Topics: Amines; Animals; Carcinogens; Chemical Industry; Cyanates; Female; Male; Mice; Mice, Inbred Strains; Phenols; Plastics; Rats; Rats, Inbred F344; Rubber; Toluene 2,4-Diisocyanate	1984
An asthma model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate. International archives of allergy and immunology, 1993, Volume: 101, Issue:1 Topics: Administration, Intranasal; Animals; Asthma; Disease Models, Animal; Guinea Pigs; Histamine Release; Immunoglobulin E; Immunoglobulin G; Lung; Male; Passive Cutaneous Anaphylaxis; Respiration; Toluene 2,4-Diisocyanate	1993
Experimental study on respiratory sensitivity to inhaled toluene diisocyanate. Archives of toxicology, 1993, Volume: 67, Issue:6 Topics: Administration, Inhalation; Animals; Antibody Specificity; Disease Models, Animal; Female; Guinea Pigs; Histamine Release; Immunoglobulin G; Lung; Mast Cells; Prostaglandins E; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate	1993
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1994, Volume: 24, Issue:1 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Eosinophilia; Female; Humans; Isocyanates; Leukocyte Count; Male; Occupational Diseases; Sputum; Toluene 2,4-Diisocyanate	1994
Determination of toluenediamine isomers by capillary gas chromatography and chemical ionization mass spectrometry with special reference to the biological monitoring of 2,4- and 2,6-toluene diisocyanate. Journal of chromatography. A, 1994, Mar-11, Volume: 663, Issue:2 Topics: Chromatography, Gas; Fluorocarbons; Humans; Hydrolysis; Indicators and Reagents; Isomerism; Mass Spectrometry; Phenylenediamines; Reference Standards; Toluene 2,4-Diisocyanate; Trifluoroacetic Acid	1994
Degradation of polyurethane foams used in the Même breast implant. Journal of biomedical materials research, 1993, Volume: 27, Issue:10 Topics: Biocompatible Materials; Drug Contamination; Female; Humans; Mammaplasty; Phenylenediamines; Polyurethanes; Prostheses and Implants; Toluene 2,4-Diisocyanate	1993
Biological monitoring of occupational exposure to toluene diisocyanate. International archives of occupational and environmental health, 1993, Volume: 65, Issue:2 Topics: Air Pollutants, Occupational; Environmental Monitoring; Humans; Maximum Allowable Concentration; Occupational Exposure; Phenylenediamines; Skin Absorption; Toluene 2,4-Diisocyanate	1993
Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate. Occupational and environmental medicine, 1996, Volume: 53, Issue:2 Topics: Air Pollution; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hydrolysis; Isomerism; Occupational Exposure; Phenylenediamines; Toluene 2,4-Diisocyanate	1996
Formation, solvolysis, and transcarbamoylation reactions of bis(S-glutathionyl) adducts of 2,4- and 2,6-diisocyanatotoluene. Chemical research in toxicology, 1997, Volume: 10, Issue:4 Topics: Amino Acid Sequence; Carbamates; Chromatography, High Pressure Liquid; Glutathione; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Solvents; Toluene 2,4-Diisocyanate	1997
Albumin adducts in plasma from workers exposed to toluene diisocyanate. The Analyst, 1997, Volume: 122, Issue:2 Topics: Albumins; Chromatography, Gel; Chromatography, Ion Exchange; Humans; Occupational Exposure; Toluene 2,4-Diisocyanate	1997
A comparative respiratory sensitization study of 2,4- and 2,6-toluene diisocyanate using guinea pigs. Inhalation toxicology, 2000, Volume: 12, Issue:7 Topics: Administration, Inhalation; Aerosols; Air Pollutants, Occupational; Anaphylaxis; Animals; Body Weight; Drug Hypersensitivity; Guinea Pigs; Haptens; Inhalation Exposure; Male; Plethysmography, Whole Body; Respiration; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate	2000
Exposure to 2,4- and 2,6-toluene diisocyanate (TDI) during production of flexible foam: determination of airborne TDI and urinary 2,4- and 2,6-toluenediamine (TDA). The Analyst, 2001, Volume: 126, Issue:7 Topics: Adult; Air Pollutants, Occupational; Chemical Industry; Chromatography, High Pressure Liquid; Environmental Monitoring; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Occupational Exposure; Phenylenediamines; Toluene 2,4-Diisocyanate	2001
LC-MS determination of urinary toluenediamine in workers exposed to toluenediisocyanate. Toxicology letters, 2002, Aug-05, Volume: 134, Issue:1-3 Topics: Chromatography, Liquid; Environmental Monitoring; Humans; Inhalation Exposure; Mass Spectrometry; Occupational Exposure; Phenylenediamines; Toluene 2,4-Diisocyanate	2002
Role of tumor necrosis factor in toluene diisocyanate asthma. American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:4 Topics: Allergens; Animals; Antigens, CD; Asthma; B7-2 Antigen; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunoglobulin E; Immunoglobulin G; Interferon-gamma; Interleukin-4; Lymph Nodes; Membrane Glycoproteins; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Occupational Exposure; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; Time Factors; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2002
Determination of unreacted 2,4-toluene diisocyanate (2,4TDI) and 2,6-toluene diisocyanate (2,6TDI) in foams at ultratrace level by using HPLC-CIS-MS-MS. The Analyst, 2003, Volume: 128, Issue:12 Topics: Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Mass Spectrometry; Microchemistry; Sensitivity and Specificity; Toluene 2,4-Diisocyanate	2003
Quantitative determination of hexamethylene diisocyanate (HDI), 2,4-toluene diisocyanate (2,4-TDI) and 2,6-toluene diisocyanate (2,6-TDI) monomers at ppt levels in air by alkaline adduct coordination ionspray tandem mass spectrometry. Journal of environmental monitoring : JEM, 2005, Volume: 7, Issue:2 Topics: Air Pollutants, Occupational; Cyanates; Environmental Monitoring; Humans; Isocyanates; Isomerism; Mass Spectrometry; Sensitivity and Specificity; Specimen Handling; Toluene 2,4-Diisocyanate	2005
Urinary excretion of toluene diisocyanates in rats following dermal exposure. Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:2 Topics: Administration, Cutaneous; Animals; Area Under Curve; Dose-Response Relationship, Drug; Environmental Pollutants; Half-Life; Male; Models, Animal; Models, Biological; Rats; Rats, Sprague-Dawley; Skin Absorption; Toluene 2,4-Diisocyanate	2008
Quantum chemistry studies of far-infrared spectra of aromatic urethanes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2008, Nov-01, Volume: 71, Issue:1 Topics: Carbon; Models, Chemical; Molecular Conformation; Nitrogen; Oxygen; Quantum Theory; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Temperature; Toluene 2,4-Diisocyanate; Urethane	2008
The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate. Pharmacogenetics and genomics, 2010, Volume: 20, Issue:2 Topics: Adult; Amino Acid Substitution; Biomarkers; Female; Genotype; Glutathione S-Transferase pi; Humans; Isoleucine; Male; Middle Aged; Phenylenediamines; Polymorphism, Single Nucleotide; Toluene 2,4-Diisocyanate; Valine; Young Adult	2010
Determination of the toluene diisocyanate binding sites on human serum albumin by tandem mass spectrometry. Analytical biochemistry, 2011, Jul-15, Volume: 414, Issue:2 Topics: Amino Acid Sequence; Binding Sites; Humans; Isomerism; Molecular Sequence Data; Protein Binding; Serum Albumin; Tandem Mass Spectrometry; Toluene 2,4-Diisocyanate	2011
Gene expression profiles in auricle skin as a possible additional endpoint for determination of sensitizers: A multi-endpoint evaluation of the local lymph node assay. Toxicology letters, 2017, Oct-05, Volume: 280 Topics: Animals; Cytokines; Dinitrochlorobenzene; Ear Auricle; Female; Gene Expression Regulation; Local Lymph Node Assay; Mice; Mice, Inbred CBA; Oxazolone; Salicylates; Skin; Sodium Dodecyl Sulfate; Toluene 2,4-Diisocyanate; Transcriptome	2017