Page last updated: 2024-08-23

2,6-diaminopurine and guanine

2,6-diaminopurine has been researched along with guanine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19907 (24.14)18.7374
1990's7 (24.14)18.2507
2000's6 (20.69)29.6817
2010's8 (27.59)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Fernández, JR; Firestein, BL; Sweet, ES; Welsh, WJ1
Chaudhary, D; Chauhan, V; Dhaked, RK; Pathak, U; Saxena, N1
Carlson, EE; Goswami, M; Wilke, KE1
Clifford, AJ; Clifford, CK; Ho, YK; Koehn, DJ; Sobieski, RJ1
Garber, BB; Gots, JS1
Bailly, C; Travers, AA; Waring, MJ1
Beigelman, L; Cech, TR; Strobel, SA; Usman, N1
Bailly, C; Waring, MJ2
Day, RS; Xu, YZ1
Dubois, S; Eritja, R; Guschlbauer, W; Thielking, V1
Kozlov, IA; Orgel, LE1
Cairns, MJ; King, A; Sun, LQ1
DUNCAN, RE; SETTERFIELD, G1
GUTHRIE, R; LU, WC1
Doláková, P; Holý, A; Masojídková, M1
MORGAN, HR1
Arent, S; Frieden, M; Jensen, FR; Koch, T; Larsen, S; Pedersen, DS; Rosenbohm, C1
Andrei, G; De Clercq, E; Snoeck, R1
BENDICH, A; BROWN, GB; FURST, SS1
Arar, K; Gamper, HB; Gewirtz, A; Hou, YM1
BONDICH, A; BROWN, GB1
Matsika, S; Mburu, E1
Arico, JW; Calhoun, AK; McLaughlin, LW1
Jeong, LS; Kim, G; Naik, SD; Qu, S; Sahu, PK; Umme, T; Yu, J1
Kamble, NR; Sigurdsson, ST1
Hornum, M; Kumar, P; Nielsen, P; Nielsen, RB; Petersen, M; Sharma, PK; Stendevad, J1
Chen, J; Pang, L; Wang, X; Zhang, JZH; Zhu, T1
Chatterjee, S; Daher, M; Lund, PE; Walter, NG1

Other Studies

29 other study(ies) available for 2,6-diaminopurine and guanine

ArticleYear
Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine.
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Binding Sites; Cognition Disorders; Energy Metabolism; Guanine; Guanine Deaminase; Humans; Kinetics; Ligands; Liver Diseases; Microtubules; Molecular Dynamics Simulation; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship

2010
In Silico Discovery and Validation of Amide Based Small Molecule Targeting the Enzymatic Site of Shiga Toxin.
    Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23

    Topics: Amides; Animals; Cells, Cultured; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Discovery; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Shiga Toxin; Small Molecule Libraries; Structure-Activity Relationship; Vero Cells

2016
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship

2017
Effects of purine amino groups on the development of Drosophila.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:2

    Topics: 2-Aminopurine; Adenine; Animals; Charcoal; Drosophila melanogaster; Guanine; Larva; Purines

1984
Utilization of 2,6-diaminopurine by Salmonella typhimurium.
    Journal of bacteriology, 1980, Volume: 143, Issue:2

    Topics: 2-Aminopurine; Adenine; Adenosine Deaminase; Guanine; Mutation; Purine-Nucleoside Phosphorylase; Purines; Salmonella typhimurium

1980
Effects of base substitutions on the binding of a DNA-bending protein.
    Journal of molecular biology, 1995, Oct-13, Volume: 253, Issue:1

    Topics: 2-Aminopurine; Base Sequence; Carrier Proteins; DNA Footprinting; DNA-Binding Proteins; DNA, Bacterial; Factor For Inversion Stimulation Protein; Guanine; Inosine; Integration Host Factors; Molecular Sequence Data; Nucleic Acid Conformation; Promoter Regions, Genetic; RNA, Transfer, Tyr

1995
The 2,6-diaminopurine riboside.5-methylisocytidine wobble base pair: an isoenergetic substitution for the study of G.U pairs in RNA.
    Biochemistry, 1994, Nov-22, Volume: 33, Issue:46

    Topics: 2-Aminopurine; Amides; Base Composition; Base Sequence; Cytidine; Guanine; Molecular Sequence Data; Phosphoric Acids; RNA; Thermodynamics; Uridine

1994
The purine 2-amino group as a critical recognition element for binding of small molecules to DNA.
    Gene, 1994, Nov-04, Volume: 149, Issue:1

    Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Autoradiography; Base Sequence; Dactinomycin; Deoxyribonuclease I; DNA; Echinomycin; Guanine; Inosine; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; RNA, Transfer, Tyr

1994
Transferring the purine 2-amino group from guanines to adenines in DNA changes the sequence-specific binding of antibiotics.
    Nucleic acids research, 1995, Mar-25, Volume: 23, Issue:6

    Topics: 2-Aminopurine; Adenine; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Dinucleoside Phosphates; DNA; Guanine; Inosine; Intercalating Agents; Ligands; Molecular Sequence Data; Peptides; RNA, Transfer, Tyr

1995
Incision at diaminopurine: thymine base pairs but not at guanine:O4-methylthymine base pairs in DNA by extracts of human cells.
    Biochemistry, 1995, Jun-06, Volume: 34, Issue:22

    Topics: 2-Aminopurine; Base Composition; Base Sequence; Cell Line; Cell-Free System; DNA; Glioma; Guanine; Humans; Hydrogen Bonding; Molecular Sequence Data; Oligodeoxyribonucleotides; Thymine; Tumor Cells, Cultured

1995
Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers: nonmethylated substrates.
    Biological chemistry, 1997, Volume: 378, Issue:5

    Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Methylation; DNA Probes; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Guanine; Hypoxanthine; Kinetics; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligonucleotide Probes; Site-Specific DNA-Methyltransferase (Adenine-Specific); Software; Substrate Specificity; Temperature; Thermodynamics; Thymine; Uracil

1997
Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues.
    Helvetica chimica acta, 1999, Volume: 82, Issue:11

    Topics: 2-Aminopurine; Adenine; Adenosine; Adenosine Monophosphate; Base Pairing; Cytidine Monophosphate; Cytosine; DNA Primers; Evolution, Chemical; Evolution, Molecular; Exobiology; Guanine; Inosine Monophosphate; RNA; Templates, Genetic; Uracil; Uridine Monophosphate

1999
Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites.
    Nucleic acids research, 2003, Jun-01, Volume: 31, Issue:11

    Topics: 2-Aminopurine; Adenine; Base Pairing; Base Sequence; Catalysis; Cytosine; DNA, Catalytic; DNA, Single-Stranded; Guanine; Hydrogen Bonding; Kinetics; Nucleic Acid Conformation; RNA; RNA, Catalytic; Substrate Specificity

2003
Cytological studies on the antimetabolite action of 2, 6-diaminopurine in Vicia faba roots.
    The Journal of biophysical and biochemical cytology, 1955, Sep-25, Volume: 1, Issue:5

    Topics: 2-Aminopurine; Adenine; Adenosine; Antimetabolites; Cell Division; Deoxyadenosines; DNA; Growth; Guanine; Hypoxanthine; Purines; Vicia faba

1955
ANTAGONISM BETWEEN PURINES IN PURINE-REQUIRING BACILLUS SUBTILIS MUTANTS.
    Archives of biochemistry and biophysics, 1964, Volume: 108

    Topics: 2-Aminopurine; Adenine; Adenine Nucleotides; Azaguanine; Bacillus subtilis; Guanine; Guanine Nucleotides; Hypoxanthines; Mercaptopurine; Metabolism; Mutation; Nucleosides; Nucleotides; Pharmacology; Purines; Research; Xanthines

1964
Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids.
    Nucleosides, nucleotides & nucleic acids, 2003, Volume: 22, Issue:12

    Topics: 2-Aminopurine; Adenine; Antineoplastic Agents; Antiviral Agents; Butyrates; Guanine; Hypoxanthines; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Purines

2003
Factors related to the growth of psittacosis virus (strain 6BC) II. Purines, pyrimidines, and other components related to nucleic acid.
    The Journal of experimental medicine, 1952, Volume: 95, Issue:3

    Topics: 2-Aminopurine; Adenine; Benzimidazoles; Guanine; Nucleic Acids; Psittacosis; Pterins; Purines; Pyrimidines

1952
LNA guanine and 2,6-diaminopurine. Synthesis, characterization and hybridization properties of LNA 2,6-diaminopurine containing oligonucleotides.
    Bioorganic & medicinal chemistry, 2004, May-01, Volume: 12, Issue:9

    Topics: 2-Aminopurine; Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Hybridization; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization

2004
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
    Antiviral research, 2004, Volume: 61, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins

2004
On the role of 2,6-diaminopurine in the biosynthesis of nucleic acid guanine.
    The Journal of biological chemistry, 1950, Volume: 185, Issue:1

    Topics: 2-Aminopurine; Guanine; Nucleic Acids; Purines

1950
Unrestricted accessibility of short oligonucleotides to RNA.
    RNA (New York, N.Y.), 2005, Volume: 11, Issue:9

    Topics: 2-Aminopurine; Base Pairing; Guanine; Hypoxanthine; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; RNA; RNA Probes; Temperature; Thiouracil

2005
2,6-Diaminopurine, a precursor of nucleic acid guanine.
    The Journal of biological chemistry, 1948, Volume: 176, Issue:3

    Topics: 2-Aminopurine; Guanine; Nucleic Acids

1948
An ab initio study of substituent effects on the excited states of purine derivatives.
    The journal of physical chemistry. A, 2008, Dec-04, Volume: 112, Issue:48

    Topics: 2-Aminopurine; Adenine; Electrons; Gases; Guanine; Hypoxanthine; Isomerism; Purines; Quantum Theory; Xanthine

2008
Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation.
    The Journal of organic chemistry, 2010, Mar-05, Volume: 75, Issue:5

    Topics: 2-Aminopurine; Adenosine; Glycosylation; Guanine; Guanosine; Molecular Structure; Nucleosides; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship

2010
Structure-Activity Relationships of Acyclic Selenopurine Nucleosides as Antiviral Agents.
    Molecules (Basel, Switzerland), 2017, Jul-12, Volume: 22, Issue:7

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cytomegalovirus; Guanine; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Nucleosides; Organoselenium Compounds; Prodrugs; Purines; Simplexvirus; Structure-Activity Relationship

2017
Purine-Derived Nitroxides for Noncovalent Spin-Labeling of Abasic Sites in Duplex Nucleic Acids.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2018, Mar-15, Volume: 24, Issue:16

    Topics: 2-Aminopurine; Adenine; Cyclic N-Oxides; Cytosine; DNA; Guanine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acids; Purines; RNA; Spin Labels; Thymine

2018
Base-Pairing Properties of Double-Headed Nucleotides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2019, May-28, Volume: 25, Issue:30

    Topics: 2-Aminopurine; Adenine; Base Pair Mismatch; Base Pairing; Cytosine; DNA; Guanine; Hypoxanthine; Models, Molecular; Nucleic Acid Conformation; Nucleotides; Thymine

2019
Effect of mutations on binding of ligands to guanine riboswitch probed by free energy perturbation and molecular dynamics simulations.
    Nucleic acids research, 2019, 07-26, Volume: 47, Issue:13

    Topics: 2-Aminopurine; Bacillus subtilis; Bacterial Proteins; Gene Expression Regulation, Bacterial; Guanine; Hypoxanthine; Ligands; Membrane Transport Proteins; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Point Mutation; Riboswitch; Structure-Activity Relationship; Thermodynamics

2019
Protein unties the pseudoknot: S1-mediated unfolding of RNA higher order structure.
    Nucleic acids research, 2020, 02-28, Volume: 48, Issue:4

    Topics: 2-Aminopurine; Binding Sites; Escherichia coli; Guanine; Ligands; Nucleic Acid Conformation; Pyrimidinones; Pyrroles; Ribosomal Proteins; Ribosomes; Riboswitch; RNA; RNA Folding; Single Molecule Imaging

2020