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2,6-diaminopurine 2',3'-dideoxyriboside and dideoxyadenosine

2,6-diaminopurine 2',3'-dideoxyriboside has been researched along with dideoxyadenosine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, BD; Broder, S; Huryn, DM; Mitsuya, H; Sim, I; Sluboski, BC; Tam, SY; Weigele, M1
Balzarini, J; Dalley, NK; De Clercq, E; Herdewijn, P; Robins, MJ; Wood, SG1
Agrawal, B; Johar, M; Kumar, R; Kunimoto, DY; Manning, T; Rai, D; Srivastav, NC1
Balzarini, J; De Clercq, E; Naesens, L; Robins, MJ1
Balzarini, J; De Clercq, E1
Baba, M; Balzarini, J; de Clercq, E; Herdewijn, P; Pauwels, R; Robins, MJ; Wood, SG1
Baba, M; Balzarini, J; De Clercq, E; Desmyter, J; Herdewijn, P; Madej, D; Pauwels, R; Robins, MJ; Zou, RM1
Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R; Robins, MJ; Zou, RM1
Balzarini, J; De Clercq, E; Herdewijn, P; Robins, MJ; Zou, RM1
Kitos, TE; Tyrrell, DL1
Howe, AY; Robins, MJ; Tyrrell, DL; Wilson, JS1

Other Studies

11 other study(ies) available for 2,6-diaminopurine 2',3'-dideoxyriboside and dideoxyadenosine

ArticleYear
Synthesis and anti-HIV activity of isonucleosides.
    Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13

    Topics: Antiviral Agents; Cells, Cultured; Chromatography, Liquid; Dideoxynucleosides; Drug Stability; Gene Products, gag; HIV-1; Humans; Isomerism; Monocytes; Spectrum Analysis; Virus Replication

1992
Nucleic acid related compounds. 57. Synthesis, x-ray crystal structure, lipophilic partition properties, and antiretroviral activities of anomeric 3'-azido-2',3'-dideoxy-2,6-diaminopurine ribosides.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Animals; Antiviral Agents; Cell Transformation, Viral; Chemical Phenomena; Chemistry; Dideoxyadenosine; Dideoxynucleosides; Mice; Microbial Sensitivity Tests; Models, Molecular; Retroviridae; Solubility; X-Ray Diffraction

1989
Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Adenosine; Alkynes; Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Dideoxynucleosides; Drug Resistance, Bacterial; Guanosine; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium bovis; Mycobacterium tuberculosis; Purine Nucleosides; Structure-Activity Relationship; Uridine

2007
Potentiating effect of ribavirin on the in vitro and in vivo antiretrovirus activities of 2',3'-dideoxyinosine and 2',3'-dideoxy-2,6-diaminopurine riboside.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3, Issue:12

    Topics: Animals; Antiviral Agents; Cell Line; Cell Transformation, Viral; Cytopathogenic Effect, Viral; Didanosine; Dideoxyadenosine; Drug Synergism; Fibroblasts; HIV; Humans; Mice; Mice, Inbred Strains; Moloney murine sarcoma virus; Ribavirin; Sarcoma, Experimental; Virus Replication

1990
The antiviral activity of 9-beta-D-arabinofuranosyladenine is enhanced by the 2',3'-dideoxyriboside, the 2',3'-didehydro-2',3'-dideoxyriboside and the 3'-azido-2',3'-dideoxyriboside of 2,6-diaminopurine.
    Biochemical and biophysical research communications, 1989, Feb-28, Volume: 159, Issue:1

    Topics: Dideoxyadenosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Synergism; Simplexvirus; Vaccinia virus; Vidarabine; Viral Plaque Assay

1989
Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus.
    Molecular pharmacology, 1988, Volume: 33, Issue:3

    Topics: Adenosine Deaminase; Antimetabolites; Antiviral Agents; Coformycin; Deoxyadenosines; Deoxyguanosine; Dideoxyadenosine; Dideoxynucleosides; HIV; Pentostatin; Prodrugs; Solubility; Virus Replication

1988
Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyriboside.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: Adenosine Deaminase; Animals; Antiviral Agents; Cell Line; Deamination; Deoxyadenosines; Dideoxyadenosine; HIV; Humans; Mice; Moloney murine sarcoma virus; Structure-Activity Relationship; Tumor Cells, Cultured

1988
The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro.
    Biochemical and biophysical research communications, 1987, May-29, Volume: 145, Issue:1

    Topics: Adenosine Deaminase Inhibitors; Animals; Antigens, Viral; Antiviral Agents; Cell Line; Cell Transformation, Viral; Deoxyadenosines; Dideoxyadenosine; DNA Replication; HIV; HIV Antigens; Humans; Virus Replication

1987
The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replication.
    Biochemical and biophysical research communications, 1987, May-29, Volume: 145, Issue:1

    Topics: Adenosine Deaminase; Animals; Cattle; Deoxyadenosines; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; HIV; Intestines; Kinetics; Nucleoside Deaminases; Substrate Specificity; Virus Replication

1987
Intracellular metabolism of 2',3'-dideoxynucleosides in duck hepatocyte primary cultures.
    Biochemical pharmacology, 1995, May-11, Volume: 49, Issue:9

    Topics: Animals; Animals, Newborn; Antiviral Agents; Cells, Cultured; Deoxycytidine; Dideoxyadenosine; Dideoxynucleosides; Ducks; Hepatitis B Virus, Duck; Liver; Phosphorylation; Zalcitabine

1995
Selective inhibition of the reverse transcription of duck hepatitis B virus by binding of 2',3'-dideoxyguanosine 5'-triphosphate to the viral polymerase.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:1

    Topics: Animals; Antiviral Agents; Blotting, Northern; Blotting, Southern; Deoxyguanine Nucleotides; Depression, Chemical; Dideoxyadenosine; Dideoxynucleotides; DNA-Directed DNA Polymerase; Ducks; Hepatitis B Virus, Duck; RNA-Directed DNA Polymerase; Transcription, Genetic; Virus Replication; Zalcitabine

1996