Compounds > 2,6-di-tert-butylphenol
Page last updated: 2024-08-23

2,6-di-tert-butylphenol and propofol

2,6-di-tert-butylphenol has been researched along with propofol in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's8 (88.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glen, JB; James, R1
Harrison, NL; Hong, X; Hopfinger, AJ; Krasowski, MD1
Kapur, S; Rosario, M; Selassie, CD; Verma, RP1
Daştan, A; Gülçin, I; Küfrevioğlu, OI; Sentürk, M; Supuran, CT1
Akabas, MH; Williams, DB1
Haeseler, G; Leuwer, M1
Ahrens, J; Bufler, J; Dengler, R; Haeseler, G; Krampfl, K; Leuwer, M; Mohammadi, B1
Endo, T; Ogata, M; Shin-Ya, K; Urano, S1
Ahrens, J; de la Roche, J; Foadi, N; Haeseler, G; Krampfl, K; Leuwer, M1

Other Studies

9 other study(ies) available for 2,6-di-tert-butylphenol and propofol

ArticleYear
Synthesis, biological evaluation, and preliminary structure-activity considerations of a series of alkylphenols as intravenous anesthetic agents.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:12

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Chemical Phenomena; Chemistry; Hypnotics and Sedatives; Lethal Dose 50; Male; Mice; Phenols; Structure-Activity Relationship

1980
4D-QSAR analysis of a set of propofol analogues: mapping binding sites for an anesthetic phenol on the GABA(A) receptor.
    Journal of medicinal chemistry, 2002, Jul-18, Volume: 45, Issue:15

    Topics: Algorithms; Anesthetics, General; Animals; Binding Sites; Excitatory Amino Acid Agonists; Humans; Hydrophobic and Hydrophilic Interactions; Larva; Ligands; Models, Molecular; Propofol; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis

2002
Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.
    Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Activation; Mice; Molecular Conformation; Phenols; Quantitative Structure-Activity Relationship; Vinblastine

2005
Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.
    Bioorganic & medicinal chemistry, 2009, Apr-15, Volume: 17, Issue:8

    Topics: Antioxidants; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Erythrocytes; Humans; Phenols

2009
Structural evidence that propofol stabilizes different GABA(A) receptor states at potentiating and activating concentrations.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-01, Volume: 22, Issue:17

    Topics: 4-Chloromercuribenzenesulfonate; Amino Acid Substitution; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Microinjections; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Phenols; Propofol; Protein Binding; Protein Conformation; Rats; Receptors, GABA-A; Structure-Activity Relationship; Sulfhydryl Reagents; Xenopus

2002
High-affinity block of voltage-operated rat IIA neuronal sodium channels by 2,6 di-tert-butylphenol, a propofol analogue.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Electrophysiology; GABA-A Receptor Antagonists; In Vitro Techniques; Ion Channel Gating; Neurons; Patch-Clamp Techniques; Phenols; Propofol; Rats; Sodium Channel Blockers; Sodium Channels

2003
2,6 di-tert-butylphenol, a nonanesthetic propofol analog, modulates alpha1beta glycine receptor function in a manner distinct from propofol.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:1

    Topics: Algorithms; Anesthetics, Intravenous; Animals; Cell Line; Dose-Response Relationship, Drug; Glycine; Patch-Clamp Techniques; Phenols; Propofol; Rats; Receptors, Glycine; RNA, Messenger; Structure-Activity Relationship; Synapses

2004
Antioxidant activity of propofol and related monomeric and dimeric compounds.
    Chemical & pharmaceutical bulletin, 2005, Volume: 53, Issue:3

    Topics: Antioxidants; Free Radical Scavengers; Lipid Peroxidation; Phenols; Propofol; Xylenes

2005
The non-anaesthetic propofol analogue 2,6-di-tert-butylphenol fails to modulate GABA(A) receptor function.
    Pharmacology, 2009, Volume: 83, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Cell Line; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; Phenols; Propofol; Rats; Receptors, GABA-A; Transfection

2009