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2,5-dimethoxy-4-bromoamphetamine and 2,5-dimethoxyamphetamine

2,5-dimethoxy-4-bromoamphetamine has been researched along with 2,5-dimethoxyamphetamine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's4 (21.05)18.2507
2000's6 (31.58)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glennon, RA; Liebowitz, SM; Mack, EC1
Hall, LH; Kier, LB1
Bartyzel, P; Glennon, RA; Leonhardt, S; Raghupathi, R; Teitler, M1
Huang, XM; Johnson, MP; Nichols, DE; Oberlender, R; Snyder, SE1
Glennon, RA; Lyon, RA; Roth, BL; Seggel, MR; Suba, EA; Titeler, M; Yousif, MY1
Glennon, RA2
Glennon, RA; Lyon, RA; McKenney, JD; Titeler, M1
Benington, F; Glennon, RA; Morin, RD; Young, R1
Anderson, GM; Castagnoli, N; Domelsmith, LN; Eaton, TA; Glennon, RA; Houk, KN; Kollman, PA; Shulgin, AT1
Anderson, GM; Glennon, RA; Liebowitz, SM1
Clare, BW1
Dowd, CS; DuPre, A; Egan, C; Glennon, RA; Herrick-Davis, K; Smith, C; Teitler, M1
Glennon, RA; Peddi, S; Roth, BL; Westkaemper, RB1
Cassels, BK; Castillo, M; Fierro, A; Gallardo-Godoy, A; McLean, TH; Nichols, DE; Reyes-Parada, M1
Kurrasch, DM; Nichols, DE; Parker, MA1
Glennon, RA; Mosier, PD; Roth, BL; Runyon, SP; Westkaemper, RB1
Ewald, AH; Maurer, HH1
Burrai, L; Nieddu, M; Palomba, M; Pirisi, MA1

Reviews

1 review(s) available for 2,5-dimethoxy-4-bromoamphetamine and 2,5-dimethoxyamphetamine

ArticleYear
Central serotonin receptors as targets for drug research.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin

1987

Other Studies

18 other study(ies) available for 2,5-dimethoxy-4-bromoamphetamine and 2,5-dimethoxyamphetamine

ArticleYear
Serotonin receptor binding affinities of several hallucinogenic phenylalkylamine and N,N-dimethyltryptamine analogues.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:8

    Topics: Amines; Animals; Female; Hallucinogens; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; N,N-Dimethyltryptamine; Rats; Receptors, Serotonin; Stomach; Tryptamines

1978
Structure-activity studies on hallucinogenic amphetamines using molecular connectivity.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:12

    Topics: Amphetamines; Chemical Phenomena; Chemistry, Physical; Hallucinogens; Models, Chemical; Structure-Activity Relationship

1977
Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: Animals; Binding Sites; Binding, Competitive; Ergolines; Ketanserin; Male; Molecular Structure; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Structure-Activity Relationship; Tritium

1992
2,3-Dihydrobenzofuran analogues of hallucinogenic phenethylamines.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Animals; Benzofurans; Cerebral Cortex; Discrimination, Psychological; Hallucinogens; Indicators and Reagents; Learning; Lysergic Acid Diethylamide; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Phenethylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Structure-Activity Relationship

1991
A structure-affinity study of the binding of 4-substituted analogues of 1-(2,5-dimethoxyphenyl)-2-aminopropane at 5-HT2 serotonin receptors.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:3

    Topics: Amphetamines; Animals; In Vitro Techniques; Ketanserin; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Solubility; Structure-Activity Relationship

1990
5-HT1 and 5-HT2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogues.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:2

    Topics: Animals; Anisoles; Binding, Competitive; Generalization, Stimulus; In Vitro Techniques; Male; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship

1986
Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:10

    Topics: Amphetamines; Animals; Behavior, Animal; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hallucinogens; In Vitro Techniques; Isomerism; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin

1982
Photoelectron spectra of psychotropic drugs. 6. Relationships between the physical properties and pharmacological actions of amphetamine analogues.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:12

    Topics: Amphetamines; Animals; Chemical Phenomena; Chemistry, Physical; Humans; Psychotropic Drugs; Rabbits; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1981
Serotonin receptor affinities of psychoactive phenalkylamine analogues.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:3

    Topics: Amines; Animals; Female; Hallucinogens; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Serotonin; Stomach; Structure-Activity Relationship

1980
The frontier orbital phase angles: novel QSAR descriptors for benzene derivatives, applied to phenylalkylamine hallucinogens.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Hallucinogens; Humans; Models, Molecular; Molecular Conformation; Phenethylamines; Quantum Theory

1998
1-[4-(3-Phenylalkyl)phenyl]-2-aminopropanes as 5-HT(2A) partial agonists.
    Journal of medicinal chemistry, 2000, Aug-10, Volume: 43, Issue:16

    Topics: 3T3 Cells; Animals; Cell Line; Inositol Phosphates; Ligands; Mice; Propylamines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship

2000
Ring substituted analogues of 5-aminomethyl-10,11-dihydro-dibenzo[a,d]cycloheptene (AMDH): potential modes of binding to the 5-HT(2A) receptor.
    Bioorganic & medicinal chemistry letters, 2003, Aug-04, Volume: 13, Issue:15

    Topics: Cyclopentanes; Indicators and Reagents; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Serotonin Agents; Structure-Activity Relationship

2003
Sulfur-substituted alpha-alkyl phenethylamines as selective and reversible MAO-A inhibitors: biological activities, CoMFA analysis, and active site modeling.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Animals; Binding Sites; Brain; Clorgyline; Crystallography, X-Ray; In Vitro Techniques; Male; Methylation; Mitochondria; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley

2005
The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands.
    Bioorganic & medicinal chemistry, 2008, Apr-15, Volume: 16, Issue:8

    Topics: Anthracenes; Catalysis; Hydrophobic and Hydrophilic Interactions; Ligands; Lipids; Molecular Structure; Phenethylamines; Protein Binding; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Animals; Anthracenes; Cattle; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis; Protein Binding; Receptor, Serotonin, 5-HT2A; Sequence Alignment; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Structure-Activity Relationship

2008
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin

2017
2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.
    Toxicology letters, 2008, Dec-15, Volume: 183, Issue:1-3

    Topics: Algorithms; Amphetamines; Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Designer Drugs; DOM 2,5-Dimethoxy-4-Methylamphetamine; Fluoxetine; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Insecta; Kinetics; Microsomes, Liver; Molecular Structure; Quinidine; Spectrometry, Mass, Electrospray Ionization

2008
Identification and quantitation of 4-bromo-2,5-dimethoxyamphetamine in seized blotters.
    Legal medicine (Tokyo, Japan), 2015, Volume: 17, Issue:1

    Topics: Amphetamines; Chromatography, Liquid; DOM 2,5-Dimethoxy-4-Methylamphetamine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Illicit Drugs; Italy; Reproducibility of Results

2015