2,5-dihydroxybenzoic acid has been researched along with salicylates in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (25.00) | 18.7374 |
| 1990's | 57 (61.96) | 18.2507 |
| 2000's | 7 (7.61) | 29.6817 |
| 2010's | 5 (5.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashraf, M; Duncan, E; Onodera, T | 1 |
| Ashraf, M; Onodera, T; Takemura, G | 1 |
| De Mattia, G; Ferro-Luzzi, A; Ghiselli, A; Laurenti, O; Maiani, G | 1 |
| Klimes, J; Sedlácek, J; Sochor, J; Zahradnícek, M | 1 |
| Denecke, B; Eichenlaub, R; Grund, E | 1 |
| Ariel, I; Chevion, M; Haskel, Y; Kitrossky, N; Udassin, R | 1 |
| Ashraf, M; Onodera, T | 1 |
| Birnbaum, LS; Blair, PC; Clark, AM; McMahon, TF; Stefanski, SA; Wilson, RE | 1 |
| Halliwell, B; Ingelman-Sundberg, M; Kaur, H; Persson, JO; Terelius, Y | 1 |
| Deshmukh, DR; Kauffman, RE; Meert, KL; Sarnaik, AP | 1 |
| Koppenol, WH; Maskos, Z; Rush, JD | 1 |
| Durán-Merás, I; Muñoz de la Peña, A; Salinas, F; Soledad Durán, M | 1 |
| Davis, WB; Husney, RM; Mays, DC; Mohammed, BS; Mohammed, JR; Sagone, AL; She, ZW | 1 |
| Martínez Tabche, L; Posadas del Rio, FA | 1 |
| Floyd, RA; Henderson, R; Watson, JJ; Wong, PK | 1 |
| Grootveld, M; Halliwell, B | 1 |
| Dull, BJ; Goldman, P; Salata, K; Van Langenhove, A | 1 |
| Kocsis, JJ; Kyle, ME | 1 |
| Amezcua, JL; Favari, L; Mourelle, M | 1 |
| Simkin, PA | 1 |
| Bochner, F; Dimitriadis, E; Imhoff, DM; Reece, PA; Ward, AD | 1 |
| Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Radomski, M | 1 |
| Hiraga, K; Takahashi, O | 1 |
| Chalmers, IM; Hunter, T; Sitar, DS | 1 |
| Galt, KA; Rice, GK | 1 |
| Hanfeld, V; Wagner, G | 1 |
| Badcock, NR; Everett, DS; Penna, AC; Sansom, LN | 1 |
| Beach, CA; Bianchine, JR; Gerber, N; Kershaw, RA; Mays, DC; Sharp, DE | 1 |
| Cassell, S; Dromgoole, SH; Furst, DE; Paulus, HE | 1 |
| Azaroual, N; Imbenotte, M; Leclerc, F; Lhermitte, M; Maschke, S; Vermeersch, G | 1 |
| Bttner, T; Gerlach, M; Kuhn, W; Müller, T | 1 |
| Kuo, JS; Lin, NN; Liu, L; Tsai, PJ; Yang, CS | 1 |
| Busto, R; Ginsberg, MD; Globus, MY; Lin, B; Schnippering, H | 1 |
| Coudray, C; Fatôme, M; Favier, A; Martin, S; Talla, M | 1 |
| Ito, T; Kondo, T; Sugita, Y | 1 |
| Laxdal, VA; Prasad, K | 1 |
| Hosokawa, H; Karashima, K; Obata, T; Soeda, T; Uchida, Y; Yamanaka, Y | 1 |
| Almagro, UA; Dawson, CA; Effros, RM; Ghio, AJ; Hacker, AD; Morrisey, J; Schapira, RM | 1 |
| Kurane, R; Nakajima, K; Nakamura, Y; Suemori, A | 1 |
| Cross, M; Endre, ZH; Kadkhodaee, M; Towner, RA | 1 |
| Castañeda-Hernández, G; Castillo-Méndez, MS; Flores-Murrieta, FJ; Granados-Soto, V; López-Muñoz, FJ | 1 |
| Giovanni, A; Hastings, TG; Liang, LP; Zigmond, MJ | 1 |
| Hosokawa, H; Obata, T; Yamanaka, Y | 1 |
| Okuyama, T; Tomita, M; Watanabe, H; Watanabe, S | 1 |
| Calinon, F; Delbarre, B; Delbarre, G | 1 |
| Althaus, JS; Andrus, PK; Cazers, AR; Hall, ED; VonVoigtlander, PF; Williams, CM | 1 |
| Goto, S; Matsumoto, Y; Ohsako, M | 1 |
| Althaus, JS; Andrus, PK; Hall, ED; VonVoigtlander, PF | 1 |
| Anderson, MS; Feix, JB; Kalyanaraman, B | 1 |
| Floyd, RA; Grammas, P; Liu, GJ; Wood, K | 1 |
| Busto, R; Ginsberg, MD; Globus, MY; Martinez, E; Morimoto, T | 1 |
| Gramsbergen, JB; Sloot, WN | 1 |
| Kim, PM; Wells, PG | 1 |
| Laxdal, VA; Prasad, K; Raney, BL; Yu, M | 2 |
| Liu, JH; Smith, PC | 1 |
| Beal, MF; Matthews, RT | 2 |
| Bissell, MG; Mohammad, AA; Petersen, JR | 1 |
| Chevion, M; Grinberg, LN; Kitrossky, N; Rachmilewitz, EA | 1 |
| Acworth, IN; Maher, TJ; McCabe, DR | 1 |
| Balchen, T; Bruhn, T; Christensen, T; Diemer, NH | 1 |
| Obata, T; Tamura, M; Yamanaka, Y | 2 |
| Obata, T; Yamanaka, Y | 1 |
| Obata, T | 1 |
| Chevion, M; Kitrossky, N; Nagler, RM | 1 |
| Hatori, K; Kondo, T; Mizuno, Y; Shimada, H; Sugita, Y | 1 |
| Blacklock, C; Campbell, G; Lawrence, JR; Paterson, JR; Wiles, D | 1 |
| Hiramatsu, M; Komatsu, M | 1 |
| Bardou, L; Berthou, F; Bodenez, P; Dreano, Y; Dupont, I; Guirriec, C; Lucas, D; Stephan, N | 1 |
| Kita, T; Kubo, K; Nakashima, T; Takahashi, M; Wagner, GC | 1 |
| Bani, M; Brogin, G; Hengstler, JG; Oesch, F; Strolin-Benedetti, M | 1 |
| Amiridze, N; Brown, OR; Dang, Y | 1 |
| Camp, DM; LeWitt, PA; Loeffler, DA | 1 |
| Hara, A; Kusakari, J; Senarita, M; Serizawa, F; Tabuchi, K | 1 |
| Ferger, B; Teismann, P | 1 |
| Brune, K; Hinz, B; Kraus, V; Pahl, A | 1 |
| Gil, M; Haïdour, A; Ramos, JL | 1 |
| Khan, W; Prithiviraj, B; Smith, DL | 1 |
| BEL, L; DELPHAUT, J | 1 |
| PREZIOSI, P; REDUZZI, F | 1 |
| PREZIOSI, P | 1 |
| HABERLAND, GL; MEDENWALD, H | 1 |
| CHRISTIAN, JE; CRABTREE, RE; DATA, JB | 1 |
| BALOUEFF, S | 1 |
| Calderón Guzmán, D; Hernández García, E; Juárez Olguín, H; Trujillo Jiménez, F | 1 |
| Lares-Asseff, I; Lazalde-Ramos, BP; Sosa-Macías, M; Villanueva-Fierro, I; Yahuaca-Mendoza, P; Zamora-Perez, A | 1 |
| Briganti, F; Bürger, S; Eppinger, E; Ferraroni, M; Peng, G; Steimer, L; Stolz, A | 1 |
| Lee, C; Ni, CK | 1 |
| Alanis-Sánchez, BM; Cruz-Maya, JA; Flores-Ortiz, CM; Guerrero-Barajas, C; Jan-Roblero, J; Macías-Palacios, Z; Mejía-Calvo, I; Pérez-Tapia, SM; Vallejo-Castillo, L; Vázquez-Leyva, S | 1 |
| Dereziński, P; Muszalska-Kolos, I; Plewa, S; Wróblewska, KB | 1 |
92 other study(ies) available for 2,5-dihydroxybenzoic acid and salicylates
| Article | Year |
|---|---|
Production of hydroxyl radicals and their disassociation from myocardial cell injury during calcium paradox.
Topics: Animals; Antioxidants; Calcium; Free Radical Scavengers; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1992 |
Quantification of hydroxyl radical and its lack of relevance to myocardial injury during early reperfusion after graded ischemia in rat hearts.
Topics: Animals; Coronary Disease; Deferoxamine; Free Radicals; Gentisates; Heart; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Time Factors | 1992 |
Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients.
Topics: Adult; Aspirin; Diabetes Mellitus, Type 1; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxylation; Male; Oxidation-Reduction; Reactive Oxygen Species; Salicylates; Thiobarbiturates | 1992 |
Simultaneous high-performance liquid chromatographic determination of salicylates in whole blood, plasma and isolated erythrocytes.
Topics: Animals; Aspirin; Cells, Cultured; Chromatography, High Pressure Liquid; Erythrocytes; Gentisates; Hippurates; Hydroxybenzoates; Rabbits; Reproducibility of Results; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1992 |
Naphthalene degradation via salicylate and gentisate by Rhodococcus sp. strain B4.
Topics: Biodegradation, Environmental; Gentisates; Hydroxybenzoates; Mixed Function Oxygenases; NADP; Naphthalenes; Oxygen Consumption; Rhodococcus; Salicylates; Salicylic Acid; Soil Microbiology; Species Specificity | 1992 |
Salicylate as an in vivo free radical trap: studies on ischemic insult to the rat intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Intestines; Male; Rats; Reperfusion Injury; Salicylates; Salicylic Acid | 1991 |
Detection of hydroxyl radicals in the post-ischemic reperfused heart using salicylate as a trapping agent.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; In Vitro Techniques; Ischemia; Male; Myocardial Reperfusion; Oxygen; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1991 |
Comparative acute nephrotoxicity of salicylic acid, 2,3-dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid in young and middle aged Fischer 344 rats.
Topics: Acetylglucosaminidase; Administration, Oral; Aging; Alanine Transaminase; Alkaline Phosphatase; Animals; Gentisates; Glycosuria; Hydroxybenzoates; Kidney; Male; Rats; Rats, Inbred F344; Salicylates; Salicylic Acid | 1991 |
Hydroxylation of salicylate by microsomal fractions and cytochrome P-450. Lack of production of 2,3-dihydroxybenzoate unless hydroxyl radical formation is permitted.
Topics: Animals; Cytochrome P-450 Enzyme System; Free Radical Scavengers; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxylation; Lipid Bilayers; Microsomes, Liver; Rabbits; Rats; Salicylates; Salicylic Acid; Substrate Specificity | 1991 |
Impaired oxidative metabolism of salicylate in Reye's syndrome.
Topics: Arthritis, Juvenile; Biotransformation; Gentisates; Humans; Hydroxybenzoates; Oxidation-Reduction; Reye Syndrome; Salicylates; Salicylic Acid | 1990 |
The hydroxylation of the salicylate anion by a Fenton reaction and T-radiolysis: a consideration of the respective mechanisms.
Topics: Azides; Chemical Phenomena; Chemistry; Edetic Acid; Free Radicals; Gamma Rays; Gentisates; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybenzoates; Hydroxylation; Iron; Kinetics; Oxidation-Reduction; Salicylates | 1990 |
Determination of salicylic acid and its metabolites in urine by derivative synchronous spectrofluorimetry.
Topics: Gentisates; Hippurates; Humans; Hydrogen-Ion Concentration; Hydroxybenzoates; Salicylates; Salicylic Acid; Spectrometry, Fluorescence | 1990 |
Hydroxylation of salicylate by activated neutrophils.
Topics: Amitrole; Azides; Chromatography, High Pressure Liquid; Cyanides; Gentisates; Glutathione; Humans; Hydroxybenzoates; Hydroxylation; Neutrophils; Peroxidase; Salicylates; Salicylic Acid; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1989 |
Effects of subchronic parathion administration on sodium salicylate excretion kinetics in female rats.
Topics: Animals; Drug Interactions; Female; Gentisates; Hippurates; Hydroxybenzoates; Kinetics; Parathion; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Sodium Salicylate; Time Factors | 1989 |
Use of salicylate with high pressure liquid chromatography and electrochemical detection (LCED) as a sensitive measure of hydroxyl free radicals in adriamycin treated rats.
Topics: Animals; Chromatography, High Pressure Liquid; Doxorubicin; Electrochemistry; Female; Free Radicals; Gentisates; Heart; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Rats; Rats, Inbred F344; Salicylates; Salicylic Acid | 1986 |
Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids.
Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Free Radicals; Gentisates; Hippurates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Salicylates; Salicylic Acid; Synovial Fluid | 1986 |
5-Aminosalicylate: oxidation by activated leukocytes and protection of cultured cells from oxidative damage.
Topics: Aminosalicylic Acids; Animals; Cell Line; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Female; Free Radicals; Gentisates; Humans; Hydrogen Peroxide; Hydroxybenzoates; Leukocytes; Lymphocyte Activation; Mesalamine; Ovary; Oxidation-Reduction; Salicylates; Salicylic Acid; Superoxides | 1987 |
Metabolism of salicylate by isolated kidney and liver mitochondria.
Topics: Animals; Ascorbic Acid; Chromatography, Thin Layer; Ferrous Compounds; Gentisates; Hydroxybenzoates; In Vitro Techniques; Kidney; Male; Mannitol; Mitochondria, Liver; Proadifen; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1986 |
Heterogeneity of changes on the disposition of aspirin in rats with CCl4-induced chronic liver damage.
Topics: Aniline Hydroxylase; Animals; Aspirin; Carbon Tetrachloride; Carboxylic Ester Hydrolases; Colchicine; Gentisates; Glucuronates; Glucuronosyltransferase; Hydroxybenzoates; Kinetics; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1987 |
Salicylate metabolites in synovial fluid.
Topics: Gentisates; Hippurates; Humans; Hydroxybenzoates; Salicylates; Statistics as Topic; Synovial Fluid | 1986 |
Direct measurement of salicylphenolic glucuronide in human urine.
Topics: Adult; Chromatography, High Pressure Liquid; Gentisates; Glucuronates; Hippurates; Humans; Hydrogen-Ion Concentration; Hydroxybenzoates; Kinetics; Magnetic Resonance Spectroscopy; Salicylates; Salicylic Acid | 1986 |
Salicylates and 12-lipoxygenase activity in human washed platelets.
Topics: Adult; Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Gentisates; Humans; Hydroxybenzoates; In Vitro Techniques; Lipoxygenase Inhibitors; Salicylamides; Salicylates; Salicylic Acid | 1986 |
Differences in the haemorrhagic toxicity of aspirin between rats and mice.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gentisates; Hydroxybenzoates; Kaolin; Liver; Male; Mice; Mice, Inbred ICR; Organ Size; Partial Thromboplastin Time; Prothrombin Time; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Species Specificity; Time Factors | 1985 |
Plasma and synovial fluid concentrations of salicylic acid and its metabolites in patients with joint effusions.
Topics: Adult; Aged; Arthritis; Aspirin; Female; Gentisates; Hippurates; Humans; Hydroxybenzoates; Male; Middle Aged; Salicylates; Salicylic Acid; Synovial Fluid | 1985 |
In vitro drug interference with home blood-glucose-measurement systems.
Topics: Acetaminophen; Ascorbic Acid; Blood Glucose; Drug Interactions; Gentisates; Glucose Oxidase; Humans; Hydroxybenzoates; Indicators and Reagents; Monitoring, Physiologic; Reagent Kits, Diagnostic; Salicylates; Salicylic Acid | 1985 |
[Synthesis of phenol-antigen conjugates by reacting N-hydroxysuccinimidic esters of hydroxybenzoic acids with human serum albumin and bovine gamma globulin].
Topics: Acetylation; Animals; Antigens; Cattle; gamma-Globulins; Gentisates; Humans; Hydroxybenzoates; Phenols; Salicylates; Salicylic Acid; Serum Albumin; Succinimides | 1982 |
Aspirin metabolites causing misinterpretation of paracetamol results.
Topics: Acetaminophen; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Gentisates; Humans; Hydroxybenzoates; Infant; Male; Salicylates; Salicylic Acid | 1984 |
Improved method for the determination of aspirin and its metabolites in biological fluids by high-performance liquid chromatography: applications to human and animal studies.
Topics: Animals; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Hydroxybenzoates; Kinetics; Rabbits; Rats; Salicylates; Salicylic Acid; Species Specificity | 1984 |
Availability of salicylate from salsalate and aspirin.
Topics: Arthritis, Rheumatoid; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Evaluation; Female; Gentisates; Humans; Hydroxybenzoates; Male; Salicylates; Salicylic Acid | 1983 |
Salicylate poisoning: two-dimensional J-resolved NMR urinalysis.
Topics: Adolescent; Aspirin; Female; Gentisates; Hippurates; Humans; Hydroxybenzoates; Magnetic Resonance Spectroscopy; Poisoning; Salicylates; Salicylic Acid | 1995 |
Aspirin as a free radical scavenger: consequences for therapy of cerebrovascular ischemia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Cerebrovascular Disorders; Cyclooxygenase Inhibitors; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid | 1995 |
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat.
Topics: Anesthesia; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kinetics; Male; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation.
Topics: Animals; Body Temperature; Corpus Striatum; Dialysis; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Kinetics; Male; Rats; Rats, Wistar; Reperfusion; Salicylates; Salicylic Acid | 1995 |
High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as an in vivo marker of oxidative stress.
Topics: Adult; Aspirin; Calibration; Chromatography, High Pressure Liquid; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Male; Oxidative Stress; Reproducibility of Results; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Bromocriptine scavenges methamphetamine-induced hydroxyl radicals and attenuates dopamine depletion in mouse striatum.
Topics: Animals; Bromocriptine; Corpus Striatum; Dopamine; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Kinetics; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Salicylates; Salicylic Acid | 1994 |
Evaluation of hydroxyl radical-scavenging property of purpurogallin using high pressure liquid chromatography.
Topics: Antioxidants; Benzocycloheptenes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Food Preservatives; Free Radical Scavengers; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Photolysis; Salicylates; Salicylic Acid; Ultraviolet Rays | 1994 |
Myocardial microdialysis of salicylic acid to detect hydroxyl radical generation during ischemia.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microchemistry; Microdialysis; Myocardial Contraction; Myocardial Ischemia; Salicylates; Salicylic Acid | 1995 |
Hydroxyl radical production and lung injury in the rat following silica or titanium dioxide instillation in vivo.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dust; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Lung; Lung Injury; Organ Size; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Silicon Dioxide; Silicosis; Titanium | 1995 |
o-, m- and p-hydroxybenzoate degradative pathways in Rhodococcus erythropolis.
Topics: cis-trans-Isomerases; Gentisates; Glutathione; Hydroxybenzoates; Isomerases; Kinetics; Mixed Function Oxygenases; Oxygen Consumption; Parabens; Rhodococcus; Salicylates; Salicylic Acid | 1995 |
Hydroxyl radical generation following ischaemia-reperfusion in cell-free perfused rat kidney.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion; Salicylates | 1995 |
Potentiation by caffeine of the analgesic effect of aspirin in the pain-induced functional impairment model in the rat.
Topics: Animals; Aspirin; Caffeine; Drug Synergism; Female; Gentisates; Hindlimb; Hydroxybenzoates; Pain; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1994 |
Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine.
Topics: Animals; Biogenic Monoamines; Brain; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Injections, Intraperitoneal; Injections, Intraventricular; Methamphetamine; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
Effect of ferrous iron on the generation of hydroxyl free radicals by liver microdialysis perfusion of salicylate.
Topics: Animals; Extracellular Space; Ferrous Compounds; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxylation; Iron Chelating Agents; Liver; Metals; Microdialysis; Perfusion; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1993 |
Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reaction.
Topics: Chromatography; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron; Micelles; Salicylates; Salicylic Acid | 1994 |
Increase of hydroxyl free radical formation during venous stasis of dogs.
Topics: Animals; Blood Proteins; Body Fluids; Dogs; Edema; Erythrocyte Count; Free Radicals; Gentisates; Hematocrit; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Models, Biological; Posture; Salicylates; Salicylic Acid; Saphenous Vein | 1993 |
The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F).
Topics: Animals; Brain Injuries; Brain Ischemia; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Lipid Peroxides; Male; Mice; Pregnatrienes; Salicylates; Salicylic Acid | 1993 |
Transport of aspirin and its metabolites through human erythrocyte membrane.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aspirin; Chemical Phenomena; Chemistry, Physical; Culture Media; Cytosol; Erythrocyte Membrane; Gentisates; Hippurates; Humans; Hydrolysis; Hydroxybenzoates; In Vitro Techniques; Salicylates; Salicylic Acid | 1993 |
Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brain.
Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Free Radicals; Gentisates; Gerbillinae; Hippocampus; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Ibuprofen; Lipid Peroxides; Male; Proadifen; Reperfusion; Salicylates; Salicylic Acid; Vitamin E | 1993 |
Enhancement of merocyanine 540-mediated phototherapy by salicylate.
Topics: Animals; Cell Survival; Drug Synergism; Gentisates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Leukemia; Leukemia L1210; Oxygen; Photochemotherapy; Photosensitizing Agents; Pyrimidinones; Salicylates; Salicylic Acid | 1993 |
Anoxia/reoxygenation induces hydroxyl free radical formation in brain microvessels.
Topics: Animals; Brain; Catalase; Chromatography, High Pressure Liquid; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Microcirculation; Oxygen; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Superoxides | 1993 |
Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats.
Topics: Acid-Base Imbalance; Analysis of Variance; Animals; Cerebral Cortex; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxylation; Iron Chelating Agents; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Regression Analysis; Salicylates; Salicylic Acid | 1996 |
Detection of salicylate and its hydroxylated adducts 2,3- and 2,5-dihydroxybenzoic acids as possible indices for in vivo hydroxyl radical formation in combination with catechol- and indoleamines and their metabolites in cerebrospinal fluid and brain tissu
Topics: Animals; Biogenic Amines; Catechols; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indoles; Magnesium; Male; Manganese Poisoning; Neostriatum; Rats; Rats, Wistar; Reference Standards; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1995 |
Phenytoin-initiated hydroxyl radical formation: characterization by enhanced salicylate hydroxylation.
Topics: Animals; Biotransformation; Female; Gentisates; Glucuronidase; Hydrolysis; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Mice; Paraquat; Phenytoin; Salicylates; Salicylic Acid; Teratogens | 1996 |
Antioxidant activity of allicin, an active principle in garlic.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Disulfides; Free Radical Scavengers; Garlic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Plants, Medicinal; Rabbits; Reactive Oxygen Species; Salicylates; Salicylic Acid; Sulfinic Acids; Tablets | 1995 |
Direct analysis of salicylic acid, salicyl acyl glucuronide, salicyluric acid and gentisic acid in human plasma and urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Gentisates; Glucuronates; Hippurates; Humans; Hydroxybenzoates; Reproducibility of Results; Salicylates; Salicylic Acid; Sensitivity and Specificity | 1996 |
Evaluation of hydroxyl radical-scavenging property of garlic.
Topics: Animals; Chromatography, High Pressure Liquid; Free Radical Scavengers; Garlic; Gentisates; Hot Temperature; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Photolysis; Plant Extracts; Plants, Medicinal; Rabbits; Salicylates; Salicylic Acid; Sensitivity and Specificity; Superoxides; Ultraviolet Rays | 1996 |
Increased 3-nitrotyrosine in brains of Apo E-deficient mice.
Topics: Animals; Apolipoproteins E; Biomarkers; Brain Chemistry; Free Radical Scavengers; Free Radicals; Gentisates; Hydroxybenzoates; Mice; Mice, Inbred C57BL; Oxidative Stress; Salicylates; Salicylic Acid; Tyrosine | 1996 |
Laser induced resonance energy transfer--a novel approach towards achieving high sensitivity in capillary electrophoresis. I. Clinical diagnostic application.
Topics: Aminosalicylic Acid; Aspirin; Benzoates; Chemistry, Clinical; Electrophoresis, Capillary; Energy Transfer; Gentisates; Hippurates; Humans; Hydroxybenzoates; Lasers; Linear Models; Salicylates; Sensitivity and Specificity | 1996 |
Hydroxyl radical generation in beta-thalassemic red blood cells.
Topics: beta-Thalassemia; Catechols; Erythrocytes; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Iron; Oxidation-Reduction; Salicylates; Salicylic Acid | 1995 |
Improved method for the estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Animals; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Drug Stability; Excitatory Amino Acid Antagonists; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney; Liver; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Salicylates; Sensitivity and Specificity | 1997 |
Evidence for formation of hydroxyl radicals during reperfusion after global cerebral ischaemia in rats using salicylate trapping and microdialysis.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Monoamine Oxidase; Rats; Rats, Wistar; Reperfusion; Salicylates; Salicylic Acid | 1994 |
Comparative study of .OH generation in brain, heart and liver using microdialysis.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Liver; Male; Microdialysis; Myocardium; Rats; Rats, Wistar; Salicylates | 1997 |
Cardiac microdialysis of salicylic acid .OH generation on nonenzymatic oxidation by norepinephrine in rat heart.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Microdialysis; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Use of microdialysis for in-vivo monitoring of hydroxyl free-radical generation in the rat.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Electric Stimulation; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Iron; Ischemia; Jejunum; Liver; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Reperfusion Injury; Salicylates; Superoxides; Sympathetic Nervous System | 1997 |
Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases.
Topics: Administration, Oral; Animals; Antioxidants; Brain; Coenzymes; Corpus Striatum; Electron Transport; Gentisates; Humans; Hydroxybenzoates; Injections; Liver; Male; Malonates; Neurodegenerative Diseases; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Ubiquinone | 1997 |
Antioxidant activity of rat parotid saliva.
Topics: Ancitabine; Animals; Antimetabolites, Antineoplastic; Antioxidants; Ascorbic Acid; Catechols; Copper; Free Radicals; Gentisates; Hydroxybenzoates; Iron; Iron Chelating Agents; Male; Manganese; Metals; Oxidation-Reduction; Parasympathomimetics; Parotid Gland; Pilocarpine; Protein Binding; Rats; Rats, Wistar; Salicylates; Saliva; Salivary Proteins and Peptides; Wound Healing | 1997 |
Evidence of hydroxyl free radical generation by calcium overload in rat myocardium.
Topics: Animals; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Gentisates; Heart; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Microdialysis; Mixed Function Oxygenases; Myocardium; Ouabain; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse.
Topics: Animals; Azepines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agonists; Enzyme Induction; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Parkinson Disease, Secondary; Receptors, Dopamine D2; Salicylates; Salicylic Acid; Tyrosine 3-Monooxygenase | 1998 |
The identification of salicylates as normal constituents of serum: a link between diet and health?
Topics: Chromatography, High Pressure Liquid; Diet; Gas Chromatography-Mass Spectrometry; Gentisates; Humans; Hydroxybenzoates; Salicylates; Salicylic Acid | 1998 |
Measurement of hydroxyl radical by salicylate in striatum of intact brain.
Topics: Animals; Chromatography, High Pressure Liquid; Convulsants; Corpus Striatum; Gentisates; Glutarates; Hydroxybenzoates; Hydroxyl Radical; Male; Methylguanidine; Microdialysis; Rats; Rats, Wistar; Salicylates | 1999 |
Involvement of cytochromes P-450 2E1 and 3A4 in the 5-hydroxylation of salicylate in humans.
Topics: Alcoholism; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Gentisates; Humans; Hydroxybenzoates; Hydroxylation; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Salicylates | 1999 |
Hydroxyl radical formation following methamphetamine administration to rats.
Topics: Animals; Body Temperature; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Injections, Intraventricular; Male; Methamphetamine; Rats; Rats, Wistar; Salicylates; Serotonin | 1999 |
Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxylation; Male; Oxidative Stress; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Salicylates | 1999 |
Hydroxyl radicals detected via brain microdialysis in rats breathing air and during hyperbaric oxygen convulsions.
Topics: Air; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Electron Spin Resonance Spectroscopy; Epilepsy, Tonic-Clonic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Salicylates | 1999 |
L-DOPA does not enhance hydroxyl radical formation in the nigrostriatal dopamine system of rats with a unilateral 6-hydroxydopamine lesion.
Topics: Animals; Cerebellum; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Injections; Levodopa; Male; Mesencephalon; Methamphetamine; Microdialysis; Osmolar Concentration; Oxidopamine; Rats; Rats, Sprague-Dawley; Salicylates; Substantia Nigra | 2000 |
Hydroxyl radical formation in the perilymph of asphyxic guinea pig.
Topics: Animals; Asphyxia; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Guinea Pigs; Hydroxybenzoates; Hydroxyl Radical; Perilymph; Salicylates | 2000 |
The salicylate hydroxylation assay to measure hydroxyl free radicals induced by local application of glutamate in vivo or induced by the Fenton reaction in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Methods; Microdialysis; Rats; Rats, Wistar; Salicylates | 2000 |
Salicylate metabolites inhibit cyclooxygenase-2-dependent prostaglandin E(2) synthesis in murine macrophages.
Topics: Acyl Coenzyme A; Animals; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gentisates; Hydroxybenzoates; Inflammation; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Sodium Salicylate | 2000 |
Degradation of o-methoxybenzoate by a two-member consortium made up of a gram-positive Arthrobacter strain and a gram-negative Pantotea strain.
Topics: Anisoles; Arthrobacter; Biodegradation, Environmental; Gentisates; Gram-Negative Bacteria; Hydroxybenzoate Ethers; Hydroxybenzoates; Organometallic Compounds; Salicylates | 2000 |
Photosynthetic responses of corn and soybean to foliar application of salicylates.
Topics: Aspirin; Chlorophyll; Gases; Gentisates; Glycine max; Hydroxybenzoates; Molecular Structure; Phenols; Photosynthesis; Plant Leaves; Salicylates; Zea mays | 2003 |
[Action of the sodium salts of salicylic acid, gentisic acid, p-aminosalicylic acid benzoly-p-aminosalicylic acid on choleresis diuresis in the dog under chloralose anesthesia].
Topics: Aminosalicylic Acid; Anesthesia; Anesthesiology; Animals; Bile; Chloralose; Cholagogues and Choleretics; Diuresis; Diuretics; Dogs; Gentisates; Salicylates; Salicylic Acid; Salts; Sodium | 1952 |
[Pharmacological research on new salicylic and gentisic acid derivatives. III. Blood pressure and respiratory changes].
Topics: Blood Pressure; Blood Pressure Determination; Gentisates; Pressure; Respiration; Salicylates | 1955 |
[Pharmacological research on new salicylic and gentisic acid derivatives. IV. Effect on the autonomic nervous system].
Topics: Anthelmintics; Autonomic Nervous System; Gentisates; Research; Salicylates | 1955 |
[Metabolic studies on drugs. I. Synthesis of radiocarbon labelled salicylic acid (carboxy-C14), acetetylsalicylic acid (carboxy-C14 & acetyl-1-C14), salicyluric acid (carbamyl-C14), and gentisic acid (carboxy-C14)].
Topics: Aspirin; Gentisates; Hippurates; Salicylates; Uric Acid | 1957 |
A study of the oxidative metabolism of acetylsalicylic, salicylic, and gentisic acid in fevered animals.
Topics: Animals; Aspirin; Fever; Gentisates; Salicylates; Salicylic Acid | 1958 |
[Comparison of the antipyretic effect of N. acetylsalicylamide, amidofebrine, acetylsalicylic acid, gentisic acid and antipyrine].
Topics: Antipyretics; Antipyrine; Aspirin; Gentisates; Salicylates | 1950 |
Assessment of antioxidant effect of 2,5-dihydroxybenzoic acid and vitamin a in brains of rats with induced hyperoxia.
Topics: Animals; Antioxidants; Brain Chemistry; Female; Free Radicals; Gentisates; Glutathione; Hyperoxia; Oxidative Stress; Rats; Rats, Sprague-Dawley; Salicylates; Sodium-Potassium-Exchanging ATPase; Vitamin A | 2007 |
HPLC method for quantification of oxidative stress by salicilate hydroxylation in human plasma.
Topics: Biomarkers; Catechols; Chromatography, High Pressure Liquid; Drug Stability; Gentisates; Humans; Hydroxybenzoates; Hydroxylation; Linear Models; Oxidative Stress; Reproducibility of Results; Salicylates; Sensitivity and Specificity | 2010 |
Function of different amino acid residues in the reaction mechanism of gentisate 1,2-dioxygenases deduced from the analysis of mutants of the salicylate 1,2-dioxygenase from Pseudaminobacter salicylatoxidans.
Topics: Alphaproteobacteria; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Dioxygenases; Escherichia coli; Gene Expression; Gentisates; Kinetics; Molecular Sequence Data; Mutation; Naphthols; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; Salicylates; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity | 2015 |
Soft Matrix-Assisted Laser Desorption/Ionization for Labile Glycoconjugates.
Topics: Gangliosides; Gentisates; Glucans; Glycoconjugates; Heparin; Hydroxybenzoate Ethers; Ionic Liquids; Nanostructures; Salicylates; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2019 |
Utilization of naproxen by Amycolatopsis sp. Poz 14 and detection of the enzymes involved in the degradation metabolic pathway.
Topics: Actinomycetales; Biodegradation, Environmental; Biotransformation; Carbamazepine; Carbon; Catechol 1,2-Dioxygenase; Catechols; Dioxygenases; Environmental Pollution; Gentisates; Hydroxybenzoate Ethers; Kinetics; Metabolic Networks and Pathways; Mixed Function Oxygenases; Naphthalenes; Naproxen; Salicylates | 2019 |
Choline Salicylate Analysis: Chemical Stability and Degradation Product Identification.
Topics: Choline; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Gentisates; Hydrolysis; Hydroxybenzoates; Molecular Structure; Photolysis; Salicylates; Tandem Mass Spectrometry | 2019 |