2,5-dihydroxybenzoic acid has been researched along with hydroxyl radical in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.22) | 18.7374 |
| 1990's | 62 (68.89) | 18.2507 |
| 2000's | 20 (22.22) | 29.6817 |
| 2010's | 6 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashraf, M; Duncan, E; Onodera, T | 1 |
| Ashraf, M; Onodera, T; Takemura, G | 1 |
| Bredl, CR; Foerder, CA; Gmur, DJ; Schimpf, BA; Zager, RA | 1 |
| Cavallo, G; Chessa, MA; Milazzotto, F; Natale, E; Pensa, V; Ricci, R; Tubaro, E; Tubaro, M | 1 |
| Calinon, F; Delbarre, B; Delbarre, G; Floyd, RA | 1 |
| Ariel, I; Chevion, M; Haskel, Y; Kitrossky, N; Udassin, R | 1 |
| Ashraf, M; Onodera, T | 1 |
| Floyd, RA; Henderson, R; Watson, JJ; Wong, PK | 1 |
| Grootveld, M; Halliwell, B | 1 |
| Alonso, O; Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY | 1 |
| Kuo, JS; Lin, NN; Liu, L; Tsai, PJ; Yang, CS | 1 |
| Busto, R; Ginsberg, MD; Globus, MY; Lin, B; Schnippering, H | 1 |
| Coudray, C; Fatôme, M; Favier, A; Martin, S; Talla, M | 1 |
| Ashraf, M; Cai, Q; Takemura, G | 1 |
| Naoi, M; Ohkuwa, T; Sato, Y | 1 |
| Király, I; Patthy, M; Sziráki, I | 1 |
| Ito, T; Kondo, T; Sugita, Y | 1 |
| Calinon, F; Delbarre, B; Delbarre, G | 2 |
| Laxdal, VA; Prasad, K | 2 |
| Hosokawa, H; Karashima, K; Obata, T; Soeda, T; Uchida, Y; Yamanaka, Y | 1 |
| Almagro, UA; Dawson, CA; Effros, RM; Ghio, AJ; Hacker, AD; Morrisey, J; Schapira, RM | 1 |
| Cross, M; Endre, ZH; Kadkhodaee, M; Towner, RA | 1 |
| Giovanni, A; Hastings, TG; Liang, LP; Zigmond, MJ | 1 |
| Hosokawa, H; Obata, T; Yamanaka, Y | 2 |
| Okuyama, T; Tomita, M; Watanabe, H; Watanabe, S | 1 |
| Andrus, PK; Hall, ED; Zhang, JR | 1 |
| Althaus, JS; Andrus, PK; Cazers, AR; Hall, ED; VonVoigtlander, PF; Williams, CM | 1 |
| Andrus, PK; Hall, ED; Yonkers, PA | 1 |
| Althaus, JS; Andrus, PK; Hall, ED; VonVoigtlander, PF | 1 |
| Anderson, MS; Feix, JB; Kalyanaraman, B | 1 |
| Floyd, RA; Grammas, P; Liu, GJ; Wood, K | 1 |
| Gramsbergen, JB; Sloot, WN | 1 |
| Boulu, RG; Callebert, J; Lancelot, E; Plotkine, M; Revaud, ML | 1 |
| Kim, PM; Wells, PG | 1 |
| Laxdal, VA; Prasad, K; Raney, BL; Yu, M | 2 |
| Chevion, M; Drenger, B; Elami, A; Ginosar, Y; Glantz, L; Gozal, Y; Kitrossky, N; Navot, N | 1 |
| Prasad, K | 1 |
| Chevion, M; Grinberg, LN; Kitrossky, N; Rachmilewitz, EA | 1 |
| Acworth, IN; Maher, TJ; McCabe, DR | 1 |
| Balchen, T; Bruhn, T; Christensen, T; Diemer, NH | 1 |
| Obata, T; Tamura, M; Yamanaka, Y | 2 |
| Obata, T; Yamanaka, Y | 1 |
| Obata, T | 1 |
| Huang, NC; Quast, MJ; Wei, J | 1 |
| Ferger, B; Kuschinsky, K; Seyfried, C; van Amsterdam, C | 1 |
| Lee, KT; Liu, TZ; Tsai, LY | 1 |
| Hatori, K; Kondo, T; Mizuno, Y; Shimada, H; Sugita, Y | 1 |
| Cann-Moisan, C; Caroff, J; Duine, JM; Floch, F; Mialon, P | 1 |
| McHugh, NA; Merrill, GF; Powell, SR | 1 |
| Hiramatsu, M; Komatsu, M | 1 |
| Acworth, IN; Beal, MF; Bogdanov, MB; McCabe, DR | 1 |
| Natoli, S; Violi, F | 1 |
| Huguet, F; Piriou, A; Pontcharraud, R; Remblier, C; Tallineau, C | 1 |
| Blandini, F; Desideri, S; Godi, L; Mancini, F; Martignoni, E; Nappi, G; Pacchetti, C | 1 |
| Kita, T; Kubo, K; Nakashima, T; Takahashi, M; Wagner, GC | 1 |
| Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK | 1 |
| Jantze, H; Rauca, C; Zerbe, R | 1 |
| Bartsch, H; Owen, RW; Spiegelhalder, B | 1 |
| Amiridze, N; Brown, OR; Dang, Y | 1 |
| Gronow, G; Mályusz, M; Moussavian, M | 1 |
| Camp, DM; LeWitt, PA; Loeffler, DA | 1 |
| Ferger, B; Teismann, P | 2 |
| Hara, A; Kusakari, J; Senarita, M; Serizawa, F; Tabuchi, K | 1 |
| Mohanakumar, KP; Muralikrishnan, D; Thomas, B | 1 |
| Brus, R; Kostrzewa, JP; Kostrzewa, RM | 1 |
| Albers, DW; Andreassen, OA; Beal, MF; Carlson, EJ; Dedeoglu, A; Epstein, CJ; Ferrante, RJ; Klivenyi, P | 1 |
| McConnell, P; Merrill, G; Powell, S; Vandyke, K | 1 |
| Gu, J; Li, XJ; Lu, SD; Sun, FY | 1 |
| Banerjee, R; Mohanakumar, KP; Sairam, K; Saravanan, KS | 1 |
| Horiguchi, T; Inamasu, J; Kawase, T; Ogino, M; Shimizu, K; Suga, S | 1 |
| Adibhatla, RM; Dempsey, RJ; Hatcher, JF | 1 |
| Arai, M; Chen, X; Fujiwara, H; Fujiwara, T; Lu, C; Minatoguchi, S; Takemura, G; Uno, Y; Wang, N | 1 |
| Akao, S; Arai, M; Fujiwara, H; Fukuda, K; Hashimoto, K; Minatoguchi, S; Takemura, G; Uno, Y; Wang, N; Xue-Hai, C | 1 |
| Berenshtein, E; Chevion, M; Drenger, B; Gozal, Y; Raphael, J; Rivo, J | 1 |
| Dahchour, A; De Witte, P; Lallemand, F; Ward, RJ | 1 |
| Jiao, XQ; Li, SM; Liu, B; Liu, M; Mi, R; Qian, MR; Wang, L; Wu, D | 1 |
| Endo, T; Hara, S; Kuriiwa, F; Mizukami, H | 1 |
| Bao, N; Fujiwara, H; Fujiwara, T; Iwasa, M; Kawamura, I; Kobayashi, H; Minatoguchi, S; Nishigaki, K; Sumi, S; Takemura, G; Yamada, Y; Yasuda, S; Zhang, Z | 1 |
| Bosco, GM; Camporesi, EM; Chen, C; Xie, Y; Yang, ZJ | 1 |
| Kodíček, M; Svoboda, M | 1 |
| Cole, RB; Fortier, CA; Guan, B; McAvey, KM; Tarr, MA | 1 |
| Brzonova, I; Guebitz, GM; Nyanhongo, GS; Steiner, W; Zankel, A | 1 |
| Adhikari, S; Gangabhagirathi, R; Joshi, R; Mukherjee, T; Venu, S | 1 |
| Jarkovsky, J; Novakova, M; Paulova, H; Stracina, T; Taborska, E | 1 |
1 trial(s) available for 2,5-dihydroxybenzoic acid and hydroxyl radical
| Article | Year |
|---|---|
Peripheral markers of oxidative stress in Parkinson's disease. The role of L-DOPA.
Topics: Antiparkinson Agents; Biomarkers; Blood Platelets; Dopamine; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Levodopa; Linear Models; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Sodium Salicylate; Superoxide Dismutase; Tyrosine | 1999 |
89 other study(ies) available for 2,5-dihydroxybenzoic acid and hydroxyl radical
| Article | Year |
|---|---|
Production of hydroxyl radicals and their disassociation from myocardial cell injury during calcium paradox.
Topics: Animals; Antioxidants; Calcium; Free Radical Scavengers; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1992 |
Quantification of hydroxyl radical and its lack of relevance to myocardial injury during early reperfusion after graded ischemia in rat hearts.
Topics: Animals; Coronary Disease; Deferoxamine; Free Radicals; Gentisates; Heart; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Time Factors | 1992 |
Evidence against increased hydroxyl radical production during oxygen deprivation-reoxygenation proximal tubular injury.
Topics: Acute Kidney Injury; Animals; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Rats; Rats, Inbred Strains; Reperfusion Injury | 1992 |
Demonstration of the formation of hydroxyl radicals in acute myocardial infarction in man using salicylate as probe.
Topics: Aspirin; Chromatography, High Pressure Liquid; Female; Free Radicals; Gentisates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Tissue Plasminogen Activator | 1992 |
Glutamate accumulation and increased hydroxyl free radical formation in the abdominal aorta and heart of gerbil after ischemia/reperfusion insult.
Topics: Animals; Aorta, Abdominal; Female; Free Radicals; Gentisates; Gerbillinae; Glutamates; Glutamic Acid; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardium; Reperfusion Injury | 1992 |
Salicylate as an in vivo free radical trap: studies on ischemic insult to the rat intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Intestines; Male; Rats; Reperfusion Injury; Salicylates; Salicylic Acid | 1991 |
Detection of hydroxyl radicals in the post-ischemic reperfused heart using salicylate as a trapping agent.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; In Vitro Techniques; Ischemia; Male; Myocardial Reperfusion; Oxygen; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1991 |
Use of salicylate with high pressure liquid chromatography and electrochemical detection (LCED) as a sensitive measure of hydroxyl free radicals in adriamycin treated rats.
Topics: Animals; Chromatography, High Pressure Liquid; Doxorubicin; Electrochemistry; Female; Free Radicals; Gentisates; Heart; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Rats; Rats, Inbred F344; Salicylates; Salicylic Acid | 1986 |
Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids.
Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Free Radicals; Gentisates; Hippurates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Salicylates; Salicylic Acid; Synovial Fluid | 1986 |
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia.
Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothermia; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1995 |
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat.
Topics: Anesthesia; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kinetics; Male; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation.
Topics: Animals; Body Temperature; Corpus Striatum; Dialysis; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Kinetics; Male; Rats; Rats, Wistar; Reperfusion; Salicylates; Salicylic Acid | 1995 |
High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as an in vivo marker of oxidative stress.
Topics: Adult; Aspirin; Calibration; Chromatography, High Pressure Liquid; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Male; Oxidative Stress; Reproducibility of Results; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Antioxidative properties of histidine and its effect on myocardial injury during ischemia/reperfusion in isolated rat heart.
Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Disease Models, Animal; Free Radical Scavengers; Gentisates; Glutaral; Heart Ventricles; Histidine; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Phosphates; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Tissue Embedding; Ventricular Function, Left | 1995 |
Hydroxyl radical formation in diabetic rats induced by streptozotocin.
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Rats; Rats, Wistar; Streptozocin | 1995 |
Separation of dihydroxybenzoates, indicators of in-vivo hydroxyl free radical formation, in the presence of transmitter amines and some metabolites in rodent brain, using high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Biogenic Amines; Chromatography, High Pressure Liquid; Corpus Striatum; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Inbred C57BL | 1995 |
Bromocriptine scavenges methamphetamine-induced hydroxyl radicals and attenuates dopamine depletion in mouse striatum.
Topics: Animals; Bromocriptine; Corpus Striatum; Dopamine; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Kinetics; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Salicylates; Salicylic Acid | 1994 |
Action of trimetazidine on retina of gerbils after ischemia reperfusion insult: determination of .OH, amino acids, and electroretinogram.
Topics: Amino Acids; Animals; Aspartic Acid; Electroretinography; Female; gamma-Aminobutyric Acid; Gentisates; Gerbillinae; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Ischemia; Male; Reperfusion Injury; Retina; Retinal Vessels; Trimetazidine | 1994 |
Evaluation of hydroxyl radical-scavenging property of purpurogallin using high pressure liquid chromatography.
Topics: Antioxidants; Benzocycloheptenes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Food Preservatives; Free Radical Scavengers; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Photolysis; Salicylates; Salicylic Acid; Ultraviolet Rays | 1994 |
Hydroxyl radical-scavenging property of indomethacin.
Topics: Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indomethacin; Photolysis; Sensitivity and Specificity; Ultraviolet Rays | 1994 |
Myocardial microdialysis of salicylic acid to detect hydroxyl radical generation during ischemia.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microchemistry; Microdialysis; Myocardial Contraction; Myocardial Ischemia; Salicylates; Salicylic Acid | 1995 |
Hydroxyl radical production and lung injury in the rat following silica or titanium dioxide instillation in vivo.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dust; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Lung; Lung Injury; Organ Size; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Silicon Dioxide; Silicosis; Titanium | 1995 |
Hydroxyl radical generation following ischaemia-reperfusion in cell-free perfused rat kidney.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypoxia; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion; Salicylates | 1995 |
Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine.
Topics: Animals; Biogenic Monoamines; Brain; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Injections, Intraperitoneal; Injections, Intraventricular; Methamphetamine; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
In vivo monitoring of norepinephrine and hydroxyl free radical generation by ferrous iron in the myocardium with a microdialysis technique.
Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Ferrous Compounds; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Male; Microdialysis; Myocardium; Norepinephrine; Perfusion; Rats; Rats, Wistar | 1993 |
Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reaction.
Topics: Chromatography; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Iron; Micelles; Salicylates; Salicylic Acid | 1994 |
Increase of hydroxyl free radical formation during venous stasis of dogs.
Topics: Animals; Blood Proteins; Body Fluids; Dogs; Edema; Erythrocyte Count; Free Radicals; Gentisates; Hematocrit; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Models, Biological; Posture; Salicylates; Salicylic Acid; Saphenous Vein | 1993 |
In vivo monitoring of norepinephrine and .OH generation on myocardial ischemic injury by dialysis technique.
Topics: Animals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Norepinephrine; Rats; Rats, Wistar | 1994 |
Age-related regional changes in hydroxyl radical stress and antioxidants in gerbil brain.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Body Water; Brain; Cerebral Cortex; Corpus Striatum; Gentisates; Gerbillinae; Glutathione; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Neurons; Organ Specificity; Oxidation-Reduction; Pyramidal Tracts; Vitamin E | 1993 |
The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F).
Topics: Animals; Brain Injuries; Brain Ischemia; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Lipid Peroxides; Male; Mice; Pregnatrienes; Salicylates; Salicylic Acid | 1993 |
Brain hydroxyl radical generation in acute experimental head injury.
Topics: Acute Disease; Animals; Antioxidants; Brain; Craniocerebral Trauma; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Mice; Mice, Inbred Strains; Pregnatrienes; Prosencephalon; Time Factors | 1993 |
Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brain.
Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Free Radicals; Gentisates; Gerbillinae; Hippocampus; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Ibuprofen; Lipid Peroxides; Male; Proadifen; Reperfusion; Salicylates; Salicylic Acid; Vitamin E | 1993 |
Enhancement of merocyanine 540-mediated phototherapy by salicylate.
Topics: Animals; Cell Survival; Drug Synergism; Gentisates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Leukemia; Leukemia L1210; Oxygen; Photochemotherapy; Photosensitizing Agents; Pyrimidinones; Salicylates; Salicylic Acid | 1993 |
Anoxia/reoxygenation induces hydroxyl free radical formation in brain microvessels.
Topics: Animals; Brain; Catalase; Chromatography, High Pressure Liquid; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Microcirculation; Oxygen; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Superoxides | 1993 |
Detection of salicylate and its hydroxylated adducts 2,3- and 2,5-dihydroxybenzoic acids as possible indices for in vivo hydroxyl radical formation in combination with catechol- and indoleamines and their metabolites in cerebrospinal fluid and brain tissu
Topics: Animals; Biogenic Amines; Catechols; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Indoles; Magnesium; Male; Manganese Poisoning; Neostriatum; Rats; Rats, Wistar; Reference Standards; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1995 |
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage.
Topics: Analysis of Variance; Animals; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1995 |
Phenytoin-initiated hydroxyl radical formation: characterization by enhanced salicylate hydroxylation.
Topics: Animals; Biotransformation; Female; Gentisates; Glucuronidase; Hydrolysis; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Mice; Paraquat; Phenytoin; Salicylates; Salicylic Acid; Teratogens | 1996 |
Antioxidant activity of allicin, an active principle in garlic.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Disulfides; Free Radical Scavengers; Garlic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Plants, Medicinal; Rabbits; Reactive Oxygen Species; Salicylates; Salicylic Acid; Sulfinic Acids; Tablets | 1995 |
Evaluation of hydroxyl radical-scavenging property of garlic.
Topics: Animals; Chromatography, High Pressure Liquid; Free Radical Scavengers; Garlic; Gentisates; Hot Temperature; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Liver; Malondialdehyde; Photolysis; Plant Extracts; Plants, Medicinal; Rabbits; Salicylates; Salicylic Acid; Sensitivity and Specificity; Superoxides; Ultraviolet Rays | 1996 |
Halothane prevents postischemic production of hydroxyl radicals in the canine heart.
Topics: Anesthetics, Inhalation; Animals; Dogs; Gentisates; Halothane; Hydroxybenzoates; Hydroxyl Radical; Myocardial Ischemia; Myocardium | 1997 |
Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seed.
Topics: Butylene Glycols; Chromatography, High Pressure Liquid; Free Radical Scavengers; Gentisates; Glucosides; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Seeds; Sensitivity and Specificity; Ultraviolet Rays | 1997 |
Hydroxyl radical generation in beta-thalassemic red blood cells.
Topics: beta-Thalassemia; Catechols; Erythrocytes; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Iron; Oxidation-Reduction; Salicylates; Salicylic Acid | 1995 |
Improved method for the estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Animals; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Drug Stability; Excitatory Amino Acid Antagonists; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney; Liver; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Salicylates; Sensitivity and Specificity | 1997 |
Evidence for formation of hydroxyl radicals during reperfusion after global cerebral ischaemia in rats using salicylate trapping and microdialysis.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Monoamine Oxidase; Rats; Rats, Wistar; Reperfusion; Salicylates; Salicylic Acid | 1994 |
Comparative study of .OH generation in brain, heart and liver using microdialysis.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Liver; Male; Microdialysis; Myocardium; Rats; Rats, Wistar; Salicylates | 1997 |
Cardiac microdialysis of salicylic acid .OH generation on nonenzymatic oxidation by norepinephrine in rat heart.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Microdialysis; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Use of microdialysis for in-vivo monitoring of hydroxyl free-radical generation in the rat.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Electric Stimulation; Gentisates; Hydrogen Peroxide; Hydroxybenzoates; Hydroxyl Radical; Iron; Ischemia; Jejunum; Liver; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Wistar; Reperfusion Injury; Salicylates; Superoxides; Sympathetic Nervous System | 1997 |
Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion.
Topics: Animals; Arterial Occlusive Diseases; Cerebral Arteries; Cerebral Infarction; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; In Vitro Techniques; Magnetic Resonance Imaging; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1997 |
Evidence of hydroxyl free radical generation by calcium overload in rat myocardium.
Topics: Animals; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Gentisates; Heart; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Microdialysis; Mixed Function Oxygenases; Myocardium; Ouabain; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1997 |
Effects of alpha-phenyl-tert-butylnitrone and selegiline on hydroxyl free radicals in rat striatum produced by local application of glutamate.
Topics: Administration, Topical; Animals; Corpus Striatum; Cyclic N-Oxides; Free Radical Scavengers; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nitrogen Oxides; Rats; Rats, Wistar; Selegiline | 1998 |
Evidence for accelerated generation of hydroxyl radicals in experimental obstructive jaundice of rats.
Topics: Animals; Cholestasis, Intrahepatic; Common Bile Duct Diseases; Constriction; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Leukocyte Count; Male; Rats; Rats, Wistar | 1998 |
Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse.
Topics: Animals; Azepines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agonists; Enzyme Induction; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Parkinson Disease, Secondary; Receptors, Dopamine D2; Salicylates; Salicylic Acid; Tyrosine 3-Monooxygenase | 1998 |
Simultaneous measurement of monoamines, their metabolites and 2,3- and 2,5-dihydroxybenzoates by high-performance liquid chromatography with electrochemical detection. Application to rat brain dialysates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Corpus Striatum; Dopamine; Gentisates; Homovanillic Acid; Hydroxybenzoates; Hydroxyindoleacetic Acid; Hydroxyl Radical; Methoxyhydroxyphenylglycol; Norepinephrine; Oxygen; Rats; Restraint, Physical; Serotonin | 1998 |
Estrogen diminishes postischemic hydroxyl radical production.
Topics: Animals; Dogs; Estrogens, Conjugated (USP); Female; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Sex Factors | 1998 |
Measurement of hydroxyl radical by salicylate in striatum of intact brain.
Topics: Animals; Chromatography, High Pressure Liquid; Convulsants; Corpus Striatum; Gentisates; Glutarates; Hydroxybenzoates; Hydroxyl Radical; Male; Methylguanidine; Microdialysis; Rats; Rats, Wistar; Salicylates | 1999 |
Estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Chromatography, Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Models, Chemical; Oxidative Stress; Parabens; Salicylic Acid; Tyrosine | 1999 |
[Oxidative stress and hypercholesterolemia: increase of radical hydroxyl in patients with hypercholesterolemia].
Topics: Adult; Aged; Cholesterol; Chromatography, High Pressure Liquid; Chromatography, Liquid; Data Interpretation, Statistical; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Hypercholesterolemia; Leukocytes; Male; Middle Aged; Oxidative Stress | 1999 |
Lactic acid-induced increase of extracellular dopamine measured by microdialysis in rat striatum: evidence for glutamatergic and oxidative mechanisms.
Topics: Acidosis, Lactic; Animals; Antioxidants; Chromans; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electrochemistry; Gentisates; Glutamic Acid; Hydrogen-Ion Concentration; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Lactic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1999 |
Hydroxyl radical formation following methamphetamine administration to rats.
Topics: Animals; Body Temperature; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Injections, Intraventricular; Male; Methamphetamine; Rats; Rats, Wistar; Salicylates; Serotonin | 1999 |
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Salicylic Acid; Tissue Distribution | 1999 |
Formation of free hydroxyl radicals after pentylenetetrazol-induced seizure and kindling.
Topics: Animals; Brain; Convulsants; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1999 |
Generation of reactive oxygen species by the faecal matrix.
Topics: Ascorbic Acid; Bacteria; Catechols; Chromatography, High Pressure Liquid; Edetic Acid; Feces; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Phytic Acid; Reactive Oxygen Species; Salicylic Acid; Xanthine Oxidase | 2000 |
Hydroxyl radicals detected via brain microdialysis in rats breathing air and during hyperbaric oxygen convulsions.
Topics: Air; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Electron Spin Resonance Spectroscopy; Epilepsy, Tonic-Clonic; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Salicylates | 1999 |
Effect of hydroxyl radical scavengers in renal cortical cells.
Topics: Animals; Benzoates; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney Cortex; Rats; Rats, Wistar | 1999 |
L-DOPA does not enhance hydroxyl radical formation in the nigrostriatal dopamine system of rats with a unilateral 6-hydroxydopamine lesion.
Topics: Animals; Cerebellum; Corpus Striatum; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Injections; Levodopa; Male; Mesencephalon; Methamphetamine; Microdialysis; Osmolar Concentration; Oxidopamine; Rats; Rats, Sprague-Dawley; Salicylates; Substantia Nigra | 2000 |
Comparison of the novel drug Ensaculin with MK-801 on the reduction of hydroxyl radical production in rat striatum after local application of glutamate.
Topics: Animals; Benzopyrans; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Microdialysis; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
Hydroxyl radical formation in the perilymph of asphyxic guinea pig.
Topics: Animals; Asphyxia; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Guinea Pigs; Hydroxybenzoates; Hydroxyl Radical; Perilymph; Salicylates | 2000 |
The salicylate hydroxylation assay to measure hydroxyl free radicals induced by local application of glutamate in vivo or induced by the Fenton reaction in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Methods; Microdialysis; Rats; Rats, Wistar; Salicylates | 2000 |
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catalepsy; Cyclooxygenase Inhibitors; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Free Radical Scavengers; Gentisates; Glutathione; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Mice; Mice, Inbred BALB C; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neuroprotective Agents; Sodium Salicylate; Substantia Nigra | 2000 |
Dopaminergic denervation enhances susceptibility to hydroxyl radicals in rat neostriatum.
Topics: Animals; Carbidopa; Chromatography, High Pressure Liquid; Denervation; Dihydroxyphenylalanine; Dopamine; Female; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Neostriatum; Pregnancy; Rats; Salicylic Acid; Serotonin | 2000 |
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Genetic Predisposition to Disease; Gentisates; Heterozygote; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mitochondria; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurotoxins; Nitro Compounds; Propionates; Salicylic Acid; Superoxide Dismutase | 2001 |
Coronary and myocardial effects of acetaminophen: protection during ischemia-reperfusion.
Topics: Acetaminophen; Animals; Coronary Circulation; Coronary Vessels; Cytoprotection; Dose-Response Relationship, Drug; Female; Gentisates; Guinea Pigs; Heart; Heart Rate; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Luminescent Measurements; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Myofibrils; Nitrates; Perfusion; Vasoconstriction; Ventricular Function, Left | 2001 |
Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical.
Topics: Animals; Brain; Dopamine; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Melatonin; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Tyrosine 3-Monooxygenase | 2002 |
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Corpus Striatum; Diclofenac; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gentisates; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Mortality; Neurodegenerative Diseases; Neuroprotective Agents; Pyrazoles; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Sodium Salicylate; Sulfonamides | 2003 |
Postischemic hypothermia inhibits the generation of hydroxyl radical following transient forebrain ischemia in rats.
Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Corpus Striatum; Extracellular Space; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hypothermia, Induced; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Xanthine | 2003 |
Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia.
Topics: Animals; Arachidonic Acid; Calcium; Cardiolipins; Cell Membrane; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Gentisates; Gerbillinae; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Intracellular Membranes; Ischemic Attack, Transient; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Salicylic Acid | 2003 |
Antidiabetic drug miglitol inhibits myocardial apoptosis involving decreased hydroxyl radical production and Bax expression in an ischaemia/reperfusion rabbit heart.
Topics: 1-Deoxynojirimycin; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blood Pressure; Blotting, Western; DNA Fragmentation; Electrophoresis, Agar Gel; Gentisates; Glucosamine; Heart Rate; Hemodynamics; Hydroxyl Radical; Hypoglycemic Agents; Imino Pyranoses; Immunohistochemistry; In Situ Nick-End Labeling; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rabbits; Time Factors | 2004 |
Lindera strychnifolia is protective against post-ischemic myocardial dysfunction through scavenging hydroxyl radicals and opening the mitochondrial KATP channels in isolated rat hearts.
Topics: Animals; Chromatography, High Pressure Liquid; Gentisates; Heart; Hydroxyl Radical; In Vitro Techniques; L-Lactate Dehydrogenase; Lindera; Male; Membrane Proteins; Myocardial Ischemia; Plant Preparations; Potassium Channels; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2004 |
Isoflurane does not mimic ischaemic preconditioning in decreasing hydroxyl radical production in the rabbit.
Topics: Anesthetics, Inhalation; Animals; Gentisates; Hemodynamics; Hydroxybenzoates; Hydroxyl Radical; Ischemic Preconditioning, Myocardial; Isoflurane; Myocardial Infarction; Rabbits | 2005 |
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Wistar; Salicylic Acid; Substance Withdrawal Syndrome; Taurine; Time Factors | 2005 |
[Impact on electrochemical degradation of phenol with different coated electrodes and inhibitors].
Topics: Electrochemistry; Electrodes; Gentisates; Hydroxyl Radical; Lead; Oxides; Phenol; Waste Disposal, Fluid; Water Pollutants, Chemical | 2007 |
Hydroxyl radical generation dependent on extracellular ascorbate in rat striatum, as determined by microdialysis.
Topics: Animals; Ascorbic Acid; Behavior, Animal; Corpus Striatum; Dehydroascorbic Acid; Extracellular Space; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 2009 |
Acarbose reduces myocardial infarct size by preventing postprandial hyperglycemia and hydroxyl radical production and opening mitochondrial KATP channels in rabbits.
Topics: Acarbose; Animals; Blood Glucose; Catechols; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; Male; Myocardial Infarction; Potassium Channels; Rabbits | 2009 |
Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Gentisates; Glutamates; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2010 |
Azo-group reduction during the matrix-assisted laser desorption/ionization process in the presence of 2,5-dihydroxybenzoic acid.
Topics: Azo Compounds; Gentisates; Hydroxyl Radical; Isomerism; Oxidation-Reduction; Peptides, Cyclic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Laser-induced oxidation of cholesterol observed during MALDI-TOF mass spectrometry.
Topics: Acetonitriles; Benzene Derivatives; Cholesterol; Gentisates; Hydroxyl Radical; Methanol; Oxidation-Reduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Enzymatic synthesis of catechol and hydroxyl-carboxic acid functionalized chitosan microspheres for iron overload therapy.
Topics: Caffeic Acids; Catechols; Chitosan; Gentisates; Glucosamine; Hydroxyl Radical; Iron; Iron Chelating Agents; Iron Overload; Laccase; Microspheres; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2011 |
Antioxidant activity and free radical scavenging reactions of gentisic acid: in-vitro and pulse radiolysis studies.
Topics: Animals; Antioxidants; Erythrocytes; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxyl Radical; Kinetics; Mitochondria, Liver; Oxidation-Reduction; Phenols; Pulse Radiolysis; Rats; Rats, Wistar | 2012 |
Hydroxyl radicals' production and ECG parameters during ischemia and reperfusion in rat, guinea pig and rabbit isolated heart.
Topics: Animals; Arrhythmias, Cardiac; Electrocardiography; Female; Gentisates; Guinea Pigs; Heart Rate; Humans; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Rabbits; Rats; Rats, Wistar | 2013 |